Bpgm (bisphosphoglycerate mutase) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Bpgm (bisphosphoglycerate mutase) Rattus norvegicus
Analyze
Symbol: Bpgm
Name: bisphosphoglycerate mutase
RGD ID: 735018
Description: Predicted to enable bisphosphoglycerate mutase activity. Involved in erythrocyte development. Human ortholog(s) of this gene implicated in familial erythrocytosis 8. Orthologous to human BPGM (bisphosphoglycerate mutase); PARTICIPATES IN Fanconi syndrome pathway; fructose-1,6-bisphosphatase deficiency pathway; gluconeogenesis pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; acrylamide.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: 2,3-bisphosphoglycerate mutase; Ab2-098; LOC296973
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8464,106,809 - 64,135,749 (+)NCBIGRCr8
mRatBN7.2463,139,730 - 63,168,581 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl463,140,018 - 63,168,581 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx468,098,223 - 68,126,740 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0464,013,920 - 64,042,437 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0462,416,337 - 62,444,854 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0461,912,210 - 61,940,697 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl461,912,210 - 61,940,696 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0461,650,881 - 61,679,069 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4461,858,884 - 61,888,007 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1462,135,013 - 62,164,136 (+)NCBI
Celera458,192,196 - 58,220,785 (+)NCBICelera
Cytogenetic Map4q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3-methylcholanthrene  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
acrylamide  (EXP)
alpha-naphthoflavone  (ISO)
antirheumatic drug  (ISO)
arsenite(3-)  (ISO)
benzo[a]pyrene  (ISO)
beta-naphthoflavone  (ISO)
bis(2-ethylhexyl) phthalate  (EXP,ISO)
bisphenol A  (EXP,ISO)
buspirone  (EXP)
Butylbenzyl phthalate  (EXP)
C60 fullerene  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
captan  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chlordecone  (ISO)
chromium(6+)  (ISO)
copper(II) sulfate  (ISO)
daidzein  (ISO)
daidzein 7-O-beta-D-glucoside  (ISO)
decabromodiphenyl ether  (ISO)
dibutyl phthalate  (EXP,ISO)
dicrotophos  (ISO)
diethyl phthalate  (EXP)
diisobutyl phthalate  (EXP)
diisononyl phthalate  (EXP)
dinophysistoxin 1  (ISO)
dioxygen  (ISO)
doxorubicin  (ISO)
fenvalerate  (EXP)
flutamide  (EXP)
folic acid  (ISO)
formaldehyde  (ISO)
genistein  (ISO)
genistein 7-O-beta-D-glucoside  (ISO)
glycidyl methacrylate  (ISO)
glycitein  (ISO)
glycitin  (ISO)
hydralazine  (ISO)
indometacin  (EXP)
leflunomide  (ISO)
Licochalcone B  (ISO)
metformin  (EXP)
methotrexate  (EXP)
methyl methanesulfonate  (ISO)
methylisothiazolinone  (ISO)
N-acetyl-L-cysteine  (ISO)
okadaic acid  (ISO)
ozone  (ISO)
paracetamol  (EXP,ISO)
pirinixic acid  (ISO)
progesterone  (ISO)
rotenone  (EXP)
senecionine  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (ISO)
sunitinib  (ISO)
thioacetamide  (EXP)
thiram  (ISO)
titanium dioxide  (ISO)
tolcapone  (EXP)
triphenyl phosphate  (ISO)
tungsten  (ISO)
urethane  (ISO)
valdecoxib  (EXP)
valproic acid  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Compound heterozygosity in a complete erythrocyte bisphosphoglycerate mutase deficiency. Lemarchandel V, etal., Blood. 1992 Nov 15;80(10):2643-9.
2. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
3. Changes in enzyme activities involved in the degradation of 1,3-bisphosphoglycerate during erythropoiesis in rat bone marrow. Pineda M, etal., Cell Biochem Funct. 1984 Oct;2(4):254-6.
4. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
5. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
6. GOA pipeline RGD automated data pipeline
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Comprehensive gene review and curation RGD comprehensive gene curation
10. Isolation, characterization, and structure of a mutant 89 Arg----Cys bisphosphoglycerate mutase. Implication of the active site in the mutation. Rosa R, etal., J Biol Chem 1989 May 15;264(14):7837-43.
11. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:23533145  


Genomics

Comparative Map Data
Bpgm
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8464,106,809 - 64,135,749 (+)NCBIGRCr8
mRatBN7.2463,139,730 - 63,168,581 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl463,140,018 - 63,168,581 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx468,098,223 - 68,126,740 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0464,013,920 - 64,042,437 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0462,416,337 - 62,444,854 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0461,912,210 - 61,940,697 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl461,912,210 - 61,940,696 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0461,650,881 - 61,679,069 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4461,858,884 - 61,888,007 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1462,135,013 - 62,164,136 (+)NCBI
Celera458,192,196 - 58,220,785 (+)NCBICelera
Cytogenetic Map4q22NCBI
BPGM
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387134,646,853 - 134,679,816 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl7134,646,811 - 134,679,816 (+)EnsemblGRCh38hg38GRCh38
GRCh377134,331,605 - 134,364,568 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 367133,982,095 - 134,015,108 (+)NCBINCBI36Build 36hg18NCBI36
Celera7129,068,953 - 129,101,988 (+)NCBICelera
Cytogenetic Map7q33NCBI
HuRef7128,633,382 - 128,666,417 (+)NCBIHuRef
CHM1_17134,265,830 - 134,298,456 (+)NCBICHM1_1
T2T-CHM13v2.07135,954,938 - 135,987,472 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v27133,675,849 - 133,708,886 (+)NCBI
Bpgm
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39634,453,291 - 34,482,071 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl634,453,142 - 34,482,548 (+)EnsemblGRCm39 Ensembl
GRCm38634,476,356 - 34,505,136 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl634,476,207 - 34,505,613 (+)EnsemblGRCm38mm10GRCm38
MGSCv37634,426,356 - 34,455,610 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36634,406,514 - 34,435,768 (+)NCBIMGSCv36mm8
Celera634,470,380 - 34,505,653 (+)NCBICelera
Cytogenetic Map6B1NCBI
cM Map615.01NCBI
Bpgm
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554947,866,693 - 7,883,641 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554947,867,295 - 7,889,440 (-)NCBIChiLan1.0ChiLan1.0
BPGM
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26171,460,435 - 171,495,458 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1723,470,693 - 23,505,705 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v07126,605,151 - 126,637,934 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.17139,111,512 - 139,144,487 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7139,123,318 - 139,144,487 (+)Ensemblpanpan1.1panPan2
BPGM
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11613,386,021 - 13,418,248 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1613,365,566 - 13,418,432 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1614,392,842 - 14,427,411 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01613,358,754 - 13,393,331 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1613,339,774 - 13,393,124 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11613,803,119 - 13,837,627 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01612,899,358 - 12,933,930 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01613,038,580 - 13,073,172 (-)NCBIUU_Cfam_GSD_1.0
Bpgm
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511821,009,042 - 21,032,454 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365791,141,598 - 1,164,630 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365791,141,637 - 1,164,554 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
BPGM
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1814,556,832 - 14,593,252 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11814,555,919 - 14,593,321 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21815,416,592 - 15,418,684 (+)NCBISscrofa10.2Sscrofa10.2susScr3
BPGM
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.121103,336,777 - 103,369,396 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl21103,336,809 - 103,372,186 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666072236,243 - 268,628 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Bpgm
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476515,145,011 - 15,163,978 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476515,139,919 - 15,162,721 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Bpgm
245 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:97
Count of miRNA genes:80
Interacting mature miRNAs:88
Transcripts:ENSRNOT00000013569
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1358352Srcrt3Stress Responsive Cort QTL 32.29blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)438465774146803430Rat
1549843Bw53Body weight QTL 530.0001body mass (VT:0001259)body weight gain (CMO:0000420)461697658103194791Rat
61445Strs3Sensitivity to stroke QTL 33cerebrum integrity trait (VT:0010549)post-insult time to onset of cerebrovascular lesion (CMO:0002343)44043338885433388Rat
6893678Bw108Body weight QTL 1082.60.006body mass (VT:0001259)body weight (CMO:0000012)44345797688457976Rat
10755501Bp390Blood pressure QTL 3902.5arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)426775591168368347Rat
1358363Sradr3Stress Responsive Adrenal Weight QTL 36.19adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)457486946102486946Rat
61336Bp21Blood pressure QTL 214.6arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)45711470578881294Rat
1549839Bw52Body weight QTL 520.0001body mass (VT:0001259)body weight gain (CMO:0000420)461697658115089733Rat
6909128Pancm4Pancreatic morphology QTL 411.35pancreas mass (VT:0010144)pancreas wet weight (CMO:0000626)42690728575585128Rat
61475Aia2Adjuvant induced arthritis QTL 25.8joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)43950527573892441Rat
8694439Bw168Body weight QTL 1689.570.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)44043341485433414Rat
8655906Rf60Renal function QTL 603.8blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)42949419581006281Rat
6909122Insul22Insulin level QTL 224.63blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)42690728575585128Rat
1354660Salc1Saline consumption QTL 111.26drinking behavior trait (VT:0001422)saline drink intake rate (CMO:0001627)444463908148090542Rat
2300179Bmd50Bone mineral density QTL 505.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)460928534105928534Rat
1298082Stresp4Stress response QTL 4blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)450119848146803430Rat
70192BpQTLcluster5Blood pressure QTL cluster 54.183arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)462933508114921294Rat
1300139Hrtrt6Heart rate QTL 62.85heart pumping trait (VT:2000009)heart rate (CMO:0000002)439524264116179656Rat
70200Alc18Alcohol consumption QTL 189.2drinking behavior trait (VT:0001422)ethanol intake volume to total fluid intake volume ratio (CMO:0001591)456647873149491524Rat
1578657Bss12Bone structure and strength QTL 128.9femur morphology trait (VT:0000559)femoral neck cross-sectional area (CMO:0001697)460220938105220938Rat
1578658Bss13Bone structure and strength QTL 138femur strength trait (VT:0010010)femoral neck polar moment of inertia (CMO:0001670)460220938105220938Rat
4889969Bss96Bone structure and strength QTL 964.9tibia size trait (VT:0100001)tibia cortical bone volume (CMO:0001725)45664777678882945Rat
2316958Gluco58Glucose level QTL 5810blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)411320076180699135Rat
4889972Bss97Bone structure and strength QTL 975.6tibia size trait (VT:0100001)tibia total bone volume (CMO:0001724)45664777678882945Rat
6478684Anxrr30Anxiety related response QTL 300.00087defecation behavior trait (VT:0010462)defecation rate (CMO:0000998)462753847107753847Rat
5685012Bmd87Bone mineral density QTL 875.1tibia mineral mass (VT:1000283)bone mineral content (CMO:0001554)45664777678882945Rat
5685009Bmd86Bone mineral density QTL 863.7tibia mineral mass (VT:1000283)bone mineral density (CMO:0001226)45664777678882945Rat
1331807Rf31Renal function QTL 312.988urine potassium amount (VT:0010539)urine potassium level (CMO:0000128)43952426474726312Rat
8552782Vie1Viral induced encephalitis QTL 126.4brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)43443048482490359Rat
634311Sach7Saccharin preference QTL 7taste sensitivity trait (VT:0001986)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)45711443281266970Rat
738009Sach4Saccharine consumption QTL 44.90.000016consumption behavior trait (VT:0002069)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)459948935154902892Rat
631261Tcas3Tongue tumor susceptibility QTL 36.88tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)41081417091360527Rat
2312567Glom19Glomerulus QTL 191.90.006kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)445456990146803430Rat
6478772Anxrr49Anxiety related response QTL 490.15488defecation behavior trait (VT:0010462)defecation rate (CMO:0000998)462753847107753847Rat
8655961Kidm43Kidney mass QTL 4318kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)436303261103194984Rat
1354612Foco1Food consumption QTL 18.87eating behavior trait (VT:0001431)food intake rate (CMO:0000427)444463908148090542Rat
2303168Bp330Blood pressure QTL 3304.250.017arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)45214602146446691Rat
8552801Bw143Body weight QTL 1437.3body mass (VT:0001259)change in body weight to body weight ratio (CMO:0002216)43443048482490359Rat
738031Alc14Alcohol consumption QTL 147.60.00003consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)459948935154902892Rat
8552807Vie4Viral induced encephalitis QTL 47.3brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)46293350882490359Rat
619616Bp79Blood pressure QTL 790.0292arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)4521460278882945Rat
1576305Emca6Estrogen-induced mammary cancer QTL 65.8mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)444463720155883716Rat
61418Pia5Pristane induced arthritis QTL 54.5joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)462277855128289560Rat
631651Bp124Blood pressure QTL 1243arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)462879517107879517Rat
8552809Vie5Viral induced encephalitis QTL 525.3brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)43443048482490359Rat
738016Alc16Alcohol consumption QTL 163.60.00015consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)459948935154902892Rat
1558651Swd3Spike wave discharge measurement QTL 34.620.000024brain electrophysiology trait (VT:0010557)brain spike-and-wave discharge frequency (CMO:0001742)45843213392991462Rat
1358203Stl19Serum triglyceride level QTL 192.80.002blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)4521829465958103Rat
1641833Alc21Alcohol consumption QTL 218.60.0001drinking behavior trait (VT:0001422)ethanol drink intake rate (CMO:0001407)456698790126192555Rat
631546Bp86Blood pressure QTL 863.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)45711443291360801Rat
6478743Anxrr40Anxiety related response QTL 400.83076defecation behavior trait (VT:0010462)defecation rate (CMO:0000998)462753847107753847Rat
7394826Bw126Body weight QTL 1260.002body mass (VT:0001259)body weight gain (CMO:0000420)46293326987483707Rat
12798520Anxrr55Anxiety related response QTL 554.450.01locomotor behavior trait (VT:0001392)number of rearing movements with lid-pushing in an experimental apparatus (CMO:0002715)432583980114627242Rat
631671Iddm11Insulin dependent diabetes mellitus QTL 113.60.0012blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)45863587778886137Rat

Markers in Region
BF393409  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2463,162,184 - 63,162,281 (+)MAPPERmRatBN7.2
Rnor_6.0461,934,290 - 61,934,386NCBIRnor6.0
Rnor_5.0461,672,961 - 61,673,057UniSTSRnor5.0
RGSC_v3.4461,880,960 - 61,881,056UniSTSRGSC3.4
Celera458,214,270 - 58,214,366UniSTS
RH 3.4 Map4376.6UniSTS
Cytogenetic Map4q22UniSTS
RH138377  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2463,167,775 - 63,167,895 (+)MAPPERmRatBN7.2
Rnor_6.0461,939,892 - 61,940,011NCBIRnor6.0
Rnor_5.0461,678,264 - 61,678,383UniSTSRnor5.0
RGSC_v3.4461,887,202 - 61,887,321UniSTSRGSC3.4
Celera458,219,980 - 58,220,099UniSTS
RH 3.4 Map4376.0UniSTS
Cytogenetic Map4q22UniSTS
RH132040  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2463,168,301 - 63,168,499 (+)MAPPERmRatBN7.2
Rnor_6.0461,940,418 - 61,940,615NCBIRnor6.0
Rnor_5.0461,678,790 - 61,678,987UniSTSRnor5.0
RGSC_v3.4461,887,728 - 61,887,925UniSTSRGSC3.4
Celera458,220,506 - 58,220,703UniSTS
RH 3.4 Map4376.0UniSTS
Cytogenetic Map4q22UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000013569   ⟹   ENSRNOP00000013566
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl463,140,018 - 63,168,581 (+)Ensembl
Rnor_6.0 Ensembl461,912,210 - 61,940,696 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000090717   ⟹   ENSRNOP00000070911
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl463,151,908 - 63,168,459 (+)Ensembl
Rnor_6.0 Ensembl461,924,013 - 61,940,573 (+)Ensembl
RefSeq Acc Id: NM_199382   ⟹   NP_955414
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8464,107,277 - 64,135,749 (+)NCBI
mRatBN7.2463,140,109 - 63,168,581 (+)NCBI
Rnor_6.0461,912,210 - 61,940,697 (+)NCBI
Rnor_5.0461,650,881 - 61,679,069 (+)NCBI
RGSC_v3.4461,858,884 - 61,888,007 (+)RGD
Celera458,192,196 - 58,220,785 (+)RGD
Sequence:
RefSeq Acc Id: XM_006236259   ⟹   XP_006236321
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8464,117,638 - 64,135,749 (+)NCBI
mRatBN7.2463,150,852 - 63,168,581 (+)NCBI
Rnor_6.0461,922,941 - 61,940,697 (+)NCBI
Rnor_5.0461,650,881 - 61,679,069 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039107293   ⟹   XP_038963221
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8464,106,809 - 64,135,749 (+)NCBI
mRatBN7.2463,139,730 - 63,168,581 (+)NCBI
RefSeq Acc Id: XM_063285747   ⟹   XP_063141817
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8464,107,231 - 64,135,749 (+)NCBI
RefSeq Acc Id: NP_955414   ⟸   NM_199382
- UniProtKB: Q6P6G4 (UniProtKB/TrEMBL),   F7F6N0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006236321   ⟸   XM_006236259
- Peptide Label: isoform X1
- UniProtKB: Q6P6G4 (UniProtKB/TrEMBL),   F7F6N0 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000070911   ⟸   ENSRNOT00000090717
Ensembl Acc Id: ENSRNOP00000013566   ⟸   ENSRNOT00000013569
RefSeq Acc Id: XP_038963221   ⟸   XM_039107293
- Peptide Label: isoform X1
- UniProtKB: Q6P6G4 (UniProtKB/TrEMBL),   F7F6N0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063141817   ⟸   XM_063285747
- Peptide Label: isoform X1
- UniProtKB: F7F6N0 (UniProtKB/TrEMBL),   Q6P6G4 (UniProtKB/TrEMBL)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q7TP58-F1-model_v2 AlphaFold Q7TP58 1-395 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13692954
Promoter ID:EPDNEW_R3478
Type:initiation region
Name:Bpgm_1
Description:bisphosphoglycerate mutase
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0461,912,210 - 61,912,270EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:735018 AgrOrtholog
BioCyc Gene G2FUF-45274 BioCyc
BioCyc Pathway PWY-6405 [Rapoport-Luebering glycolytic shunt] BioCyc
BioCyc Pathway Image PWY-6405 BioCyc
Ensembl Genes ENSRNOG00000010133 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000013569.5 UniProtKB/TrEMBL
  ENSRNOT00000090717.2 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.1240 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:6887677 IMAGE-MGC_LOAD
InterPro His_Pase_superF_clade-1 UniProtKB/TrEMBL
  His_PPase_superfam UniProtKB/TrEMBL
  PG/BPGM_mutase_AS UniProtKB/TrEMBL
  Phosphogly_mut1 UniProtKB/TrEMBL
KEGG Report rno:296973 UniProtKB/TrEMBL
MGC_CLONE MGC:72978 IMAGE-MGC_LOAD
NCBI Gene 296973 ENTREZGENE
PANTHER BISPHOSPHOGLYCERATE MUTASE UniProtKB/TrEMBL
  Phosphogly_mut1 UniProtKB/TrEMBL
Pfam PGAM UniProtKB/TrEMBL
PhenoGen Bpgm PhenoGen
PIRSF 6PFK_2-Ptase UniProtKB/TrEMBL
PROSITE PG_MUTASE UniProtKB/TrEMBL
RatGTEx ENSRNOG00000010133 RatGTEx
SMART PGAM UniProtKB/TrEMBL
Superfamily-SCOP SSF53254 UniProtKB/TrEMBL
UniProt F7F6N0 ENTREZGENE, UniProtKB/TrEMBL
  Q6P6G4 ENTREZGENE, UniProtKB/TrEMBL
  Q7TP58_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-12-02 Bpgm  bisphosphoglycerate mutase  Bpgm  2,3-bisphosphoglycerate mutase  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-09-10 Bpgm  2,3-bisphosphoglycerate mutase  LOC296973    Symbol updated 1299863 APPROVED