Gene: Pcmt1 (protein-L-isoaspartate (D-aspartate) O-methyltransferase 1) Rattus norvegicus
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Symbol: Pcmt1
Name: protein-L-isoaspartate (D-aspartate) O-methyltransferase 1
Description: ENCODES a protein that exhibits protein-L-isoaspartate (D-aspartate) O-methyltransferase activity; S-adenosylmethionine-dependent methyltransferase activity; INVOLVED IN aging; cellular response to hypoxia; negative regulation of cardiac muscle cell apoptotic process; PARTICIPATES IN homocysteine metabolic pathway; methionine cycle/metabolic pathway; ASSOCIATED WITH Aortic Injuries; malignant glioma; Alzheimer's disease (ortholog); FOUND IN basolateral plasma membrane; brush border membrane; cytoplasm; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; 3H-1,2-dithiole-3-thione
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: L-isoaspartyl protein carboxyl methyltransferase; MGC95039; PCM; PIMT; protein L-isoaspartyl/D-aspartyl methyltransferase; protein-beta-aspartate methyltransferase; Protein-L-isoaspartate (D-aspartate) O-methyltransferase; protein-L-isoaspartate(D-aspartate) O-methyltransferase
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.011,734,863 - 1,767,759 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.013,432,543 - 3,464,945 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.412,287,981 - 2,304,638 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.112,287,981 - 2,304,638 (-)NCBI
Celera1659,884 - 692,976 (-)NCBICelera
Cytogenetic Map1p13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Pcmt1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 3268
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-01-30
Status: ACTIVE