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Gene: Pcmt1 (protein-L-isoaspartate (D-aspartate) O-methyltransferase 1) Rattus norvegicus
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Symbol: Pcmt1
Name: protein-L-isoaspartate (D-aspartate) O-methyltransferase 1
Description: Exhibits protein-L-isoaspartate (D-aspartate) O-methyltransferase activity. Involved in several processes, including S-adenosylhomocysteine metabolic process; aging; and negative regulation of cardiac muscle cell apoptotic process. Localizes to several cellular components, including the brush border membrane; cytosol; and extracellular space. Biomarker of malignant glioma. Orthologous to human PCMT1 (protein-L-isoaspartate (D-aspartate) O-methyltransferase); PARTICIPATES IN homocysteine metabolic pathway; methionine cycle/metabolic pathway; INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: L-isoaspartyl protein carboxyl methyltransferase; MGC95039; PCM; PIMT; protein L-isoaspartyl/D-aspartyl methyltransferase; protein-beta-aspartate methyltransferase; Protein-L-isoaspartate (D-aspartate) O-methyltransferase; protein-L-isoaspartate(D-aspartate) O-methyltransferase
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.011,734,863 - 1,767,759 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.013,432,543 - 3,464,945 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.412,287,981 - 2,304,638 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.112,287,981 - 2,304,638 (-)NCBI
Celera1659,884 - 692,976 (-)NCBICelera
Cytogenetic Map1p13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Pcmt1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 3268
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.