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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

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Accession:CHEBI:92181 term browser browse the term
Definition:A polyether antibiotic used for prevention and treatment of coccidiosis in poultry.
Synonyms:exact_synonym: (1S,9S)-1,5:6,9-dianhydro-9-[(3R,5S,6S,7R)-9-(2-carboxy-3-hydroxy-4-methylphenyl)-6-hydroxy-5,7-dimethyl-4-oxononan-3-yl]-3,4,7,8-tetradeoxy-6-ethyl-2-C-ethyl-1,8-dimethyl-D-galacto-nonitol
 related_synonym: 6-[(3R,4S,5S,7R)-7-{(2S,3S,5S)-5-ethyl-5-[(2R,5R,6S)-5-ethyl-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]-3-methyltetrahydrofuran-2-yl}-4-hydroxy-3,5-dimethyl-6-oxononyl]-2-hydroxy-3-methylbenzoic acid;   Formula=C34H54O8;   InChI=1S/C34H54O8/c1-9-25(31-21(6)18-34(11-3,42-31)26-16-17-33(40,10-2)23(8)41-26)30(37)22(7)28(35)19(4)12-14-24-15-13-20(5)29(36)27(24)32(38)39/h13,15,19,21-23,25-26,28,31,35-36,40H,9-12,14,16-18H2,1-8H3,(H,38,39)/t19-,21+,22+,23+,25+,26-,28+,31+,33-,34+/m1/s1;   InChIKey=BBMULGJBVDDDNI-OWKLGTHSSA-N;   Ro 2-2985;   SMILES=[H][C@@]1(O[C@@](CC)(C[C@@H]1C)[C@@]1([H])CC[C@](O)(CC)[C@H](C)O1)[C@@H](CC)C(=O)[C@@H](C)[C@@H](O)[C@H](C)CCC1=C(C(O)=O)C(O)=C(C)C=C1;   X 537A;   antibiotic X 537A;   ionophore X 537A;   lasalocid A;   lasalocide;   lasalocido;   lasalocidum
 xref: CAS:25999-31-9;   DrugBank:DB11423;   KEGG:D04671;   LINCS:LSM-2214;   LIPID_MAPS_instance:LMPK09000002
 xref_mesh: MESH:D007832
 xref: PDBeChem:LSD;   PMCID:PMC6663702;   PMID:1705820;   PMID:25364932;   PMID:25535803;   PMID:25556006;   PMID:26054429;   PMID:26812337;   PMID:27580396;   PMID:28178613;   PMID:28470877;   PMID:28956164;   PMID:30191481;   PMID:30973080;   PMID:31864181;   PMID:31906353;   PMID:32069059;   PMID:32228806;   PMID:32625606;   PMID:32738374;   PMID:32774509;   Wikipedia:Lasalocid
 cyclic_relationship: is_conjugate_acid_of CHEBI:156364

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lasalocid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mapt microtubule-associated protein tau decreases expression ISO Lasalocid results in decreased expression of MAPT protein CTD PMID:16930453 NCBI chr10:92,289,002...92,386,517
Ensembl chr10:92,288,910...92,386,517
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Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19792
    role 19738
      biological role 19737
        biophysical role 12300
          membrane transport modulator 12081
            ionophore 1183
              lasalocid 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19792
    subatomic particle 19788
      composite particle 19788
        hadron 19788
          baryon 19788
            nucleon 19788
              atomic nucleus 19788
                atom 19788
                  main group element atom 19675
                    p-block element atom 19675
                      carbon group element atom 19571
                        carbon atom 19560
                          organic molecular entity 19560
                            organic group 18508
                              organic divalent group 18501
                                organodiyl group 18501
                                  carbonyl group 18404
                                    carbonyl compound 18404
                                      carboxylic acid 18079
                                        aromatic carboxylic acid 10896
                                          benzoic acids 10866
                                            benzoic acid 3820
                                              hydroxybenzoic acid 3208
                                                monohydroxybenzoic acid 1265
                                                  lasalocid 1
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