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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:ionophore
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Accession:CHEBI:24869 term browser browse the term
Definition:A compound which can carry specific ions through membranes of cells or organelles.
Synonyms:related_synonym: ionophores
 xref: Wikipedia:Ionophore


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alborixin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2 associated X, apoptosis regulator increases expression ISO alborixin results in increased expression of BAX protein CTD PMID:27378626 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO alborixin results in decreased expression of BCL2 protein CTD PMID:27378626 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Casp3 caspase 3 increases cleavage ISO alborixin results in increased cleavage of CASP3 protein CTD PMID:27378626 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp8 caspase 8 increases activity ISO alborixin results in increased activity of CASP8 protein CTD PMID:27378626 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Casp9 caspase 9 increases activity ISO alborixin results in increased activity of CASP9 protein CTD PMID:27378626 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage ISO alborixin results in increased cleavage of PARP1 protein CTD PMID:27378626 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
bafilomycin A1 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agt angiotensinogen multiple interactions EXP bafilomycin A1 inhibits the reaction [AGT protein affects the localization of Calcium] CTD PMID:21613610 NCBI chr19:57,321,594...57,333,460
Ensembl chr19:57,321,640...57,333,433
JBrowse link
G Aim2 absent in melanoma 2 multiple interactions ISO [bafilomycin A1 co-treated with [sodium arsenite results in increased abundance of Arsenic]] results in increased expression of AIM2 protein CTD PMID:32645460 NCBI chr13:91,919,834...91,963,080
Ensembl chr13:91,954,138...91,962,588
JBrowse link
G Akt1s1 AKT1 substrate 1 multiple interactions EXP bafilomycin A1 inhibits the reaction [EGF protein results in increased phosphorylation of AKT1S1 protein] CTD PMID:22689575 NCBI chr 1:100,845,443...100,851,961
Ensembl chr 1:100,845,563...100,851,960
JBrowse link
G Alb albumin decreases uptake ISO bafilomycin A1 results in decreased uptake of ALB protein CTD PMID:16313995 NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863
JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 increases expression ISO bafilomycin A1 results in increased expression of APAF1 protein CTD PMID:28483490 NCBI chr 7:31,699,309...31,784,192
Ensembl chr 7:31,699,885...31,784,192
JBrowse link
G Appl1 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 multiple interactions ISO bafilomycin A1 promotes the reaction [Lipopolysaccharides results in increased degradation of APPL1 protein]; bafilomycin A1 promotes the reaction [Poly I-C results in increased degradation of APPL1 protein] CTD PMID:25780039 NCBI chr16:2,560,103...2,602,035
Ensembl chr16:2,563,520...2,602,103
JBrowse link
G Asic1 acid sensing ion channel subunit 1 multiple interactions ISO bafilomycin A1 inhibits the reaction [Freund's Adjuvant results in increased expression of ASIC1 mRNA] CTD PMID:16769263 NCBI chr 7:141,324,714...141,354,937
Ensembl chr 7:141,326,321...141,354,937
JBrowse link
G Atg5 autophagy related 5 multiple interactions ISO ATG5 protein affects the reaction [bafilomycin A1 promotes the reaction [gossypol acetic acid results in increased expression of MAP1LC3B protein modified form]] CTD PMID:29938581 NCBI chr20:49,301,783...49,393,147
Ensembl chr20:49,318,308...49,393,140
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO bafilomycin A1 inhibits the reaction [Hydroxychloroquine results in increased activity of BAX protein] CTD PMID:12813466 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO bafilomycin A1 results in decreased expression of BCL2 mRNA CTD PMID:31310755 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Becn1 beclin 1 multiple interactions ISO bafilomycin A1 inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of BECN1 protein] CTD PMID:32645460 NCBI chr10:89,209,944...89,225,297
Ensembl chr10:89,209,940...89,225,297
JBrowse link
G Bglap bone gamma-carboxyglutamate protein multiple interactions ISO bafilomycin A1 inhibits the reaction [[Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid] results in increased expression of BGLAP mRNA] CTD PMID:23111315 NCBI chr 2:187,741,770...187,748,445
Ensembl chr 2:187,741,770...187,742,747
JBrowse link
G Bid BH3 interacting domain death agonist multiple interactions
increases cleavage
increases expression
EXP
ISO
bafilomycin A1 inhibits the reaction [manganese chloride results in increased expression of BID protein modified form]; bafilomycin A1 inhibits the reaction [manganese chloride results in increased expression of BID protein]
vistusertib affects the reaction [bafilomycin A1 results in increased cleavage of BID protein]
bafilomycin A1 results in increased expression of BID protein modified form
CTD PMID:26853465, PMID:28378122 NCBI chr 4:153,439,812...153,465,247
Ensembl chr 4:153,442,218...153,465,203
JBrowse link
G Bnip3 BCL2 interacting protein 3 increases expression
multiple interactions
ISO bafilomycin A1 results in increased expression of BNIP3 mRNA; bafilomycin A1 results in increased expression of BNIP3 protein
BNIP3 mutant form promotes the reaction [bafilomycin A1 results in increased cleavage of PARP1 protein]; capivasertib affects the reaction [bafilomycin A1 results in increased expression of BNIP3 protein]; Erlotinib Hydrochloride inhibits the reaction [bafilomycin A1 results in increased expression of BNIP3 protein]; Gefitinib inhibits the reaction [bafilomycin A1 results in increased expression of BNIP3 protein]; HIF1A mutant form inhibits the reaction [bafilomycin A1 results in increased expression of BNIP3 mRNA]; Lapatinib inhibits the reaction [bafilomycin A1 results in increased expression of BNIP3 mRNA]; vistusertib inhibits the reaction [bafilomycin A1 results in increased expression of BNIP3 protein]
CTD PMID:25981168, PMID:26853465 NCBI chr 1:211,248,098...211,265,282
Ensembl chr 1:211,248,098...211,265,282
JBrowse link
G C1qtnf9 C1q and TNF related 9 multiple interactions EXP bafilomycin A1 promotes the reaction [C1QTNF9 protein results in increased expression of MAP1LC3B protein modified form] CTD PMID:32278738 NCBI chr15:41,069,579...41,080,961
Ensembl chr15:41,069,507...41,081,159
JBrowse link
G Casp3 caspase 3 decreases activity
increases cleavage
multiple interactions
increases activity
ISO
EXP
bafilomycin A1 results in decreased activity of CASP3 protein
bafilomycin A1 results in increased cleavage of CASP3 protein
bafilomycin A1 inhibits the reaction [Cadmium results in increased cleavage of CASP3 protein]
bafilomycin A1 results in increased activity of CASP3 protein
bafilomycin A1 inhibits the reaction [manganese chloride results in increased cleavage of CASP3 protein]; bafilomycin A1 promotes the reaction [Hydrogen Peroxide results in increased expression of CASP3 protein modified form]
[bafilomycin A1 co-treated with cobaltous chloride co-treated with TP53 gene mutant form] results in increased activity of CASP3 protein; bafilomycin A1 inhibits the reaction [Soot analog results in increased expression of CASP3 protein]; bafilomycin A1 inhibits the reaction [tetrandrine results in increased cleavage of CASP3 protein]; bafilomycin A1 promotes the reaction [Atorvastatin results in increased cleavage of CASP3 protein]; bafilomycin A1 promotes the reaction [brazilin results in increased activity of CASP3 protein]; bafilomycin A1 promotes the reaction [fosbretabulin results in increased cleavage of CASP3 protein]; vistusertib affects the reaction [bafilomycin A1 results in increased cleavage of CASP3 protein]
CTD PMID:20876807, PMID:23380477, PMID:24321340, PMID:24889822, PMID:25266202, PMID:25981168, PMID:26853465, PMID:28063998, PMID:28378122, PMID:29111403, PMID:30240709 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp4 caspase 4 increases activity ISO bafilomycin A1 results in increased activity of CASP4 protein CTD PMID:20371669 NCBI chr 8:2,616,391...2,651,682
Ensembl chr 8:2,635,851...2,651,652
JBrowse link
G Casp7 caspase 7 increases activity
decreases activity
ISO bafilomycin A1 results in increased activity of CASP7 protein
bafilomycin A1 results in decreased activity of CASP7 protein
CTD PMID:20371669, PMID:25981168 NCBI chr 1:277,190,557...277,242,779
Ensembl chr 1:277,190,964...277,242,774
JBrowse link
G Casp8 caspase 8 multiple interactions EXP
ISO
bafilomycin A1 inhibits the reaction [manganese chloride results in increased cleavage of CASP8 protein]
bafilomycin A1 inhibits the reaction [Cadmium results in increased cleavage of CASP8 protein]
CTD PMID:28378122, PMID:29111403 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Casp9 caspase 9 multiple interactions EXP
ISO
bafilomycin A1 inhibits the reaction [manganese chloride results in increased cleavage of CASP9 protein]
bafilomycin A1 inhibits the reaction [Soot analog results in increased expression of CASP9 protein]
CTD PMID:28378122, PMID:30240709 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Cdc25c cell division cycle 25C multiple interactions ISO bafilomycin A1 inhibits the reaction [xanthatin results in decreased stability of CDC25C protein] CTD PMID:29074359 NCBI chr18:27,528,768...27,550,316
Ensembl chr18:27,528,354...27,550,224
JBrowse link
G Ctsb cathepsin B multiple interactions ISO bafilomycin A1 inhibits the reaction [[cobaltous chloride co-treated with TP53 gene mutant form] results in increased activity of CTSB protein]; bafilomycin A1 inhibits the reaction [Hydroxychloroquine affects the localization of CTSB protein] CTD PMID:12813466, PMID:23380477 NCBI chr15:46,316,741...46,337,613
Ensembl chr15:46,316,741...46,337,612
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 multiple interactions ISO bafilomycin A1 inhibits the reaction [CpG ODN 2216 results in increased expression of CXCL10 protein]; bafilomycin A1 inhibits the reaction [gardiquimod results in increased expression of CXCL10 protein]; bafilomycin A1 inhibits the reaction [Poly I-C results in increased expression of CXCL10 protein] CTD PMID:26682054 NCBI chr14:17,210,733...17,212,930
Ensembl chr14:17,210,733...17,212,930
JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 increases expression
multiple interactions
EXP bafilomycin A1 results in increased expression of DDIT4 protein
[EGF protein co-treated with bafilomycin A1] results in increased expression of DDIT4 protein
CTD PMID:22689575 NCBI chr20:29,509,283...29,511,382
Ensembl chr20:29,509,289...29,511,382
JBrowse link
G Egf epidermal growth factor multiple interactions EXP [bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Arginine; [bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Asparagine; [bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Isoleucine; [bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Leucine; [bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Lysine; [bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Methionine; [bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Ornithine; [bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Phenylalanine; [bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Tyrosine; [bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Valine; [bafilomycin A1 co-treated with EGF protein] results in increased abundance of Aspartic Acid; [bafilomycin A1 co-treated with EGF protein] results in increased abundance of Taurine; [EGF protein co-treated with bafilomycin A1] results in increased expression of DDIT4 protein; bafilomycin A1 inhibits the reaction [EGF protein results in increased activity of and results in increased phosphorylation of RPS6KB1 protein]; bafilomycin A1 inhibits the reaction [EGF protein results in increased phosphorylation of AKT1S1 protein]; bafilomycin A1 inhibits the reaction [EGF protein results in increased phosphorylation of EIF4EBP1 protein]; Cycloheximide inhibits the reaction [[bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Arginine]; Cycloheximide inhibits the reaction [[bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Asparagine]; Cycloheximide inhibits the reaction [[bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Isoleucine]; Cycloheximide inhibits the reaction [[bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Leucine]; Cycloheximide inhibits the reaction [[bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Lysine]; Cycloheximide inhibits the reaction [[bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Methionine]; Cycloheximide inhibits the reaction [[bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Ornithine]; Cycloheximide inhibits the reaction [[bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Phenylalanine]; Cycloheximide inhibits the reaction [[bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Tyrosine]; Cycloheximide inhibits the reaction [[bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Valine] CTD PMID:22689575 NCBI chr 2:68,820,616...68,895,537 JBrowse link
G Egfr epidermal growth factor receptor multiple interactions ISO bafilomycin A1 inhibits the reaction [Arsenic Trioxide results in decreased expression of EGFR protein] CTD PMID:30237564 NCBI chr14:99,919,485...100,104,136
Ensembl chr14:99,919,485...100,098,796
JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 multiple interactions EXP bafilomycin A1 inhibits the reaction [EGF protein results in increased phosphorylation of EIF4EBP1 protein]; bafilomycin A1 inhibits the reaction [INS protein results in increased phosphorylation of EIF4EBP1 protein] CTD PMID:22689575 NCBI chr16:68,954,860...68,968,248
Ensembl chr16:68,954,875...68,968,248
JBrowse link
G Epor erythropoietin receptor multiple interactions ISO bafilomycin A1 inhibits the reaction [Aristolochic Acids results in increased degradation of and results in decreased expression of EPOR protein] CTD PMID:26136230 NCBI chr 8:22,969,737...22,974,468
Ensembl chr 8:22,969,745...22,974,321
JBrowse link
G Faslg Fas ligand multiple interactions ISO
EXP
bafilomycin A1 inhibits the reaction [FASL protein affects the localization of Calcium]
bafilomycin A1 inhibits the reaction [manganese chloride results in increased expression of FASLG protein]
CTD PMID:20200208, PMID:28378122 NCBI chr13:79,696,811...79,717,581
Ensembl chr13:79,698,445...79,705,705
JBrowse link
G Fmc1 formation of mitochondrial complex V assembly factor 1 multiple interactions ISO bafilomycin A1 inhibits the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone results in decreased expression of FMC1 protein] CTD PMID:29371327 NCBI chr 4:66,276,835...66,284,868
Ensembl chr 4:66,276,835...66,284,868
JBrowse link
G Foxo1 forkhead box O1 multiple interactions EXP bafilomycin A1 inhibits the reaction [resveratrol inhibits the reaction [Hydrogen Peroxide results in increased acetylation of FOXO1 protein]] CTD PMID:24889822 NCBI chr 2:141,451,234...141,527,016
Ensembl chr 2:141,451,234...141,527,016
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha increases expression
multiple interactions
ISO bafilomycin A1 results in increased expression of HIF1A protein
HIF1A mutant form inhibits the reaction [bafilomycin A1 results in increased expression of BNIP3 mRNA]; HIF1A mutant form promotes the reaction [bafilomycin A1 results in increased cleavage of PARP1 protein]; lapatinib inhibits the reaction [bafilomycin A1 results in increased expression of HIF1A protein]
CTD PMID:25981168 NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052
JBrowse link
G Hmox1 heme oxygenase 1 decreases expression
multiple interactions
ISO bafilomycin A1 results in decreased expression of HMOX1 protein
bafilomycin A1 inhibits the reaction [4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole results in increased expression of HMOX1 protein]
CTD PMID:29796178 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Ifng interferon gamma decreases expression ISO bafilomycin A1 results in decreased expression of IFNG mRNA CTD PMID:16932910 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Il1b interleukin 1 beta decreases expression
multiple interactions
ISO bafilomycin A1 results in decreased expression of IL1B mRNA
[bafilomycin A1 co-treated with [sodium arsenite results in increased abundance of Arsenic]] results in increased expression of IL1B protein; bafilomycin A1 inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with aluminum sulfate] results in increased secretion of IL1B protein]
CTD PMID:16932910, PMID:24158569, PMID:32645460 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il6 interleukin 6 increases expression ISO bafilomycin A1 results in increased expression of IL6 mRNA CTD PMID:16932910 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Ins2 insulin 2 multiple interactions EXP
ISO
bafilomycin A1 inhibits the reaction [INS protein results in increased phosphorylation of EIF4EBP1 protein]; bafilomycin A1 inhibits the reaction [INS protein results in increased phosphorylation of RPS6KB1 protein]
bafilomycin A1 promotes the reaction [Palmitic Acid inhibits the reaction [INS1 protein results in increased uptake of 2-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose]]
CTD PMID:22689575, PMID:32283200 NCBI chr 1:215,856,967...215,858,034
Ensembl chr 1:215,856,971...215,858,034
JBrowse link
G Lrrk2 leucine-rich repeat kinase 2 increases response to substance ISO LRRK2 gene mutant form results in increased susceptibility to bafilomycin A1 CTD PMID:25017139 NCBI chr 7:132,857,311...133,018,549
Ensembl chr 7:132,857,628...133,018,584
JBrowse link
G Map1lc3a microtubule-associated protein 1 light chain 3 alpha multiple interactions
increases expression
ISO bafilomycin A1 promotes the reaction [Uranium results in increased expression of MAP1LC3A protein]
bafilomycin A1 results in increased expression of MAP1LC3A protein modified form
CTD PMID:30871063, PMID:31120128 NCBI chr 3:150,801,289...150,802,935
Ensembl chr 3:150,801,289...150,802,935
JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta multiple interactions
increases lipidation
increases expression
increases cleavage
decreases degradation
ISO
EXP
[di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone co-treated with bafilomycin A1] results in increased expression of MAP1LC3B mRNA; [TNF protein co-treated with bafilomycin A1] results in increased expression of MAP1LC3B protein alternative form; Acetylcysteine inhibits the reaction [di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone promotes the reaction [bafilomycin A1 results in increased expression of MAP1LC3B protein]]; ATG5 protein affects the reaction [bafilomycin A1 promotes the reaction [gossypol acetic acid results in increased expression of MAP1LC3B protein modified form]]; bafilomycin A1 affects the reaction [Ammonium Chloride results in increased metabolism of MAP1LC3B protein]; bafilomycin A1 affects the reaction [AZD4547 affects the expression of MAP1LC3B protein modified form]; bafilomycin A1 affects the reaction [AZD8186 affects the expression of MAP1LC3B protein modified form]; bafilomycin A1 inhibits the reaction [Chloroquine results in increased lipidation of MAP1LC3B protein]; bafilomycin A1 promotes the reaction [capivasertib results in increased expression of MAP1LC3B protein modified form]; bafilomycin A1 promotes the reaction [gossypol acetic acid results in increased expression of MAP1LC3B protein modified form]; bafilomycin A1 promotes the reaction [Resveratrol results in increased expression of MAP1LC3B protein alternative form]; bafilomycin A1 promotes the reaction [vistusertib results in increased expression of MAP1LC3B protein modified form]; di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone promotes the reaction [bafilomycin A1 results in increased expression of MAP1LC3B protein]; Resveratrol promotes the reaction [[TNF protein co-treated with bafilomycin A1] results in increased expression of MAP1LC3B protein alternative form]
bafilomycin A1 results in increased lipidation of MAP1LC3B protein
[Doxorubicin co-treated with bafilomycin A1] results in increased expression of MAP1LC3B protein; [Glycyrrhizic Acid co-treated with bafilomycin A1] results in increased lipidation of MAP1LC3B protein; bafilomycin A1 promotes the reaction [C1QTNF9 protein results in increased expression of MAP1LC3B protein modified form]
bafilomycin A1 results in increased expression of MAP1LC3B protein modified form
bafilomycin A1 promotes the reaction [Triiodothyronine results in increased lipidation of MAP1LC3B protein]; Triiodothyronine promotes the reaction [bafilomycin A1 results in increased lipidation of MAP1LC3B protein]
bafilomycin A1 results in increased cleavage of MAP1LC3B protein
bafilomycin A1 results in decreased degradation of MAP1LC3B protein modified form
bafilomycin A1 results in increased expression of MAP1LC3B protein; bafilomycin A1 results in increased expression of MAP1LC3B protein alternative form; bafilomycin A1 results in increased expression of MAP1LC3B protein modified form
CTD PMID:23880069, PMID:24145604, PMID:25301941, PMID:26459185, PMID:26853465, PMID:29248574, PMID:29524503, PMID:29908302, PMID:29938581, PMID:30209975, PMID:31310755, PMID:32278738, PMID:32525084 NCBI chr19:53,635,449...53,643,970
Ensembl chr19:53,629,779...53,646,058
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
increases expression
ISO bafilomycin A1 inhibits the reaction [Capsaicin results in increased activity of MAPK1 protein]; bafilomycin A1 inhibits the reaction [Iron Compounds results in increased expression of MAPK1 protein modified form]; bafilomycin A1 promotes the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased phosphorylation of MAPK1 protein]
bafilomycin A1 results in increased expression of MAPK1 protein modified form
CTD PMID:20371669, PMID:28483490, PMID:32645460 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
increases expression
ISO bafilomycin A1 inhibits the reaction [Capsaicin results in increased activity of MAPK3 protein]; bafilomycin A1 inhibits the reaction [Iron Compounds results in increased expression of MAPK3 protein modified form]; bafilomycin A1 promotes the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased phosphorylation of MAPK3 protein]
bafilomycin A1 results in increased expression of MAPK3 protein modified form
CTD PMID:20371669, PMID:28483490, PMID:32645460 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 increases phosphorylation ISO bafilomycin A1 results in increased phosphorylation of MAPK8 protein CTD PMID:31310755 NCBI chr16:9,620,854...9,709,342
Ensembl chr16:9,625,177...9,709,347
JBrowse link
G Mtor mechanistic target of rapamycin kinase decreases phosphorylation ISO bafilomycin A1 results in decreased phosphorylation of MTOR protein CTD PMID:31310755 NCBI chr 5:165,263,813...165,373,967
Ensembl chr 5:165,263,800...165,373,967
JBrowse link
G Ndrg1 N-myc downstream regulated 1 multiple interactions ISO NDRG1 protein results in decreased susceptibility to [di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone co-treated with bafilomycin A1] CTD PMID:24532803 NCBI chr 7:107,734,326...107,775,701
Ensembl chr 7:107,734,323...107,775,714
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 multiple interactions
increases expression
ISO bafilomycin A1 promotes the reaction [[Particulate Matter co-treated with Vitamin D] results in increased expression of NFE2L2 protein]; bafilomycin A1 promotes the reaction [[Silicon Dioxide co-treated with Vitamin D] results in increased expression of NFE2L2 protein]; bafilomycin A1 promotes the reaction [Particulate Matter results in increased expression of NFE2L2 protein]; bafilomycin A1 promotes the reaction [Silicon Dioxide results in increased expression of NFE2L2 protein]
bafilomycin A1 results in increased expression of NFE2L2 protein
CTD PMID:30698894 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 multiple interactions
increases expression
ISO bafilomycin A1 inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of NLRP3 protein]
bafilomycin A1 results in increased expression of NLRP3 protein
CTD PMID:32645460 NCBI chr10:45,884,324...45,918,290
Ensembl chr10:45,893,018...45,918,254
JBrowse link
G Nr5a1 nuclear receptor subfamily 5, group A, member 1 decreases expression ISO bafilomycin A1 results in decreased expression of NR5A1 protein CTD PMID:29524503 NCBI chr 3:22,998,900...23,020,441
Ensembl chr 3:22,999,616...23,020,441
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions
increases cleavage
increases expression
ISO bafilomycin A1 promotes the reaction [Atorvastatin results in increased cleavage of PARP1 protein]; bafilomycin A1 promotes the reaction [brazilin results in increased expression of PARP1 protein modified form]; bafilomycin A1 promotes the reaction [Flavanones results in increased cleavage of PARP1 protein]; bafilomycin A1 promotes the reaction [fosbretabulin results in increased cleavage of PARP1 protein]; BNIP3 mutant form promotes the reaction [bafilomycin A1 results in increased cleavage of PARP1 protein]; HIF1A mutant form promotes the reaction [bafilomycin A1 results in increased cleavage of PARP1 protein]
bafilomycin A1 inhibits the reaction [Cadmium results in increased cleavage of PARP1 protein]
bafilomycin A1 results in increased expression of PARP1 protein modified form
CTD PMID:20876807, PMID:21616090, PMID:24321340, PMID:25981168, PMID:28063998, PMID:29111403, PMID:31310755 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO bafilomycin A1 affects the localization of and results in increased activity of RELA protein CTD PMID:10339586 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Rps6kb1 ribosomal protein S6 kinase B1 decreases phosphorylation
multiple interactions
ISO
EXP
bafilomycin A1 results in decreased phosphorylation of RPS6KB1 protein
bafilomycin A1 inhibits the reaction [EGF protein results in increased activity of and results in increased phosphorylation of RPS6KB1 protein]; bafilomycin A1 inhibits the reaction [INS protein results in increased phosphorylation of RPS6KB1 protein]
CTD PMID:22689575, PMID:31310755 NCBI chr10:73,824,200...73,865,503
Ensembl chr10:73,824,202...73,865,364
JBrowse link
G Runx2 RUNX family transcription factor 2 multiple interactions ISO bafilomycin A1 inhibits the reaction [[Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid] results in increased expression of RUNX2 mRNA] CTD PMID:23111315 NCBI chr 9:18,564,743...18,773,092
Ensembl chr 9:18,564,927...18,773,092
JBrowse link
G Sirt1 sirtuin 1 multiple interactions EXP bafilomycin A1 inhibits the reaction [resveratrol inhibits the reaction [Hydrogen Peroxide results in decreased expression of SIRT1 protein]] CTD PMID:24889822 NCBI chr20:26,831,971...26,851,587
Ensembl chr20:26,833,357...26,852,199
JBrowse link
G Slc17a7 solute carrier family 17 member 7 multiple interactions EXP bafilomycin A1 inhibits the reaction [SLC17A7 protein results in increased uptake of Excitatory Amino Acid Agents]; bafilomycin A1 inhibits the reaction [SLC17A7 protein results in increased uptake of Zinc]; bafilomycin A1 inhibits the reaction [SLC30A3 protein promotes the reaction [SLC17A7 protein results in increased uptake of Zinc]] CTD PMID:15860731 NCBI chr 1:101,161,265...101,172,292
Ensembl chr 1:101,161,252...101,173,174
JBrowse link
G Slc30a3 solute carrier family 30 member 3 multiple interactions EXP bafilomycin A1 inhibits the reaction [SLC30A3 protein promotes the reaction [SLC17A7 protein results in increased uptake of Zinc]] CTD PMID:15860731 NCBI chr 6:26,629,752...26,650,106
Ensembl chr 6:26,642,783...26,650,105
JBrowse link
G Snai1 snail family transcriptional repressor 1 multiple interactions
increases expression
ISO bafilomycin A1 promotes the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of SNAI1 protein]
bafilomycin A1 results in increased expression of SNAI1 protein
CTD PMID:32645460 NCBI chr 3:164,274,710...164,279,199
Ensembl chr 3:164,274,710...164,279,378
JBrowse link
G Snca synuclein alpha multiple interactions
increases expression
ISO [bafilomycin A1 co-treated with Rotenone] results in increased expression of SNCA protein
bafilomycin A1 results in increased expression of SNCA protein
CTD PMID:26031332 NCBI chr 4:90,782,412...90,883,236
Ensembl chr 4:90,782,374...90,882,285
JBrowse link
G Sort1 sortilin 1 decreases expression ISO bafilomycin A1 results in decreased expression of SORT1 protein CTD PMID:25805502 NCBI chr 2:211,078,092...211,156,312
Ensembl chr 2:211,078,334...211,156,312
JBrowse link
G Sqstm1 sequestosome 1 increases expression
multiple interactions
ISO
EXP
bafilomycin A1 results in increased expression of SQSTM1 protein
bafilomycin A1 promotes the reaction [Hydrogen Peroxide results in increased expression of SQSTM1 protein]
[Resveratrol co-treated with bafilomycin A1] results in increased expression of SQSTM1 protein; [Silicon Dioxide co-treated with bafilomycin A1] results in increased expression of SQSTM1 protein; [Silicon Dioxide co-treated with Vitamin D co-treated with bafilomycin A1] results in increased expression of SQSTM1 protein; [TNF protein co-treated with bafilomycin A1] results in increased expression of SQSTM1 protein; [Vitamin D co-treated with bafilomycin A1] results in increased expression of SQSTM1 protein; bafilomycin A1 inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of SQSTM1 protein]; bafilomycin A1 inhibits the reaction [dactolisib results in decreased expression of SQSTM1 protein]; bafilomycin A1 inhibits the reaction [Resveratrol results in increased degradation of SQSTM1 protein]; bafilomycin A1 inhibits the reaction [Sorafenib results in decreased expression of SQSTM1 protein]; bafilomycin A1 promotes the reaction [N-Methyl-3,4-methylenedioxyamphetamine results in increased expression of SQSTM1 protein]; Fingolimod Hydrochloride affects the reaction [bafilomycin A1 results in increased expression of SQSTM1 protein]; sodium arsenite promotes the reaction [bafilomycin A1 results in increased expression of SQSTM1 protein]
[bafilomycin A1 co-treated with Rotenone] results in increased expression of SQSTM1 protein; bafilomycin A1 inhibits the reaction [Resveratrol inhibits the reaction [Streptozocin results in increased expression of SQSTM1 protein]]; bafilomycin A1 inhibits the reaction [Sirolimus results in decreased expression of SQSTM1 protein]; Streptozocin promotes the reaction [bafilomycin A1 results in increased expression of SQSTM1 protein]
CTD PMID:21778691, PMID:21858812, PMID:23151917, PMID:24145604, PMID:24238063, PMID:24889822, PMID:25939952, PMID:25943029, PMID:26031332, PMID:28125038, PMID:29248574, PMID:29524503, PMID:30698894, PMID:32186374, PMID:32645460 NCBI chr10:35,704,728...35,716,316
Ensembl chr10:35,704,730...35,716,294
JBrowse link
G Tbk1 TANK-binding kinase 1 multiple interactions ISO bafilomycin A1 promotes the reaction [Lipopolysaccharides results in increased phosphorylation of TBK1 protein]; bafilomycin A1 promotes the reaction [Poly I-C results in increased phosphorylation of TBK1 protein] CTD PMID:25780039 NCBI chr 7:63,655,247...63,687,978
Ensembl chr 7:63,655,247...63,687,978
JBrowse link
G Tlr8 toll-like receptor 8 multiple interactions ISO bafilomycin A1 inhibits the reaction [resiquimod results in increased activity of TLR8 protein] CTD PMID:21398612 NCBI chr  X:28,539,158...28,562,803
Ensembl chr  X:28,539,158...28,562,803
JBrowse link
G Tnf tumor necrosis factor increases expression
multiple interactions
ISO bafilomycin A1 results in increased expression of TNF mRNA
[TNF protein co-treated with bafilomycin A1] results in increased expression of MAP1LC3B protein alternative form; [TNF protein co-treated with bafilomycin A1] results in increased expression of SQSTM1 protein; resveratrol promotes the reaction [[TNF protein co-treated with bafilomycin A1] results in increased expression of MAP1LC3B protein alternative form]
CTD PMID:16932910, PMID:24145604 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tomm20 translocase of outer mitochondrial membrane 20 increases expression
multiple interactions
ISO bafilomycin A1 results in increased expression of TOMM20 protein
Triiodothyronine promotes the reaction [bafilomycin A1 results in increased expression of TOMM20 protein]
CTD PMID:30209975 NCBI chr19:59,863,421...59,873,411
Ensembl chr19:59,863,421...59,873,411
JBrowse link
G Tp53 tumor protein p53 multiple interactions ISO [bafilomycin A1 co-treated with cobaltous chloride co-treated with TP53 gene mutant form] results in increased activity of CASP3 protein; bafilomycin A1 inhibits the reaction [[cobaltous chloride co-treated with TP53 gene mutant form] results in increased activity of CTSB protein] CTD PMID:23380477 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Ulk1 unc-51 like autophagy activating kinase 1 multiple interactions EXP bafilomycin A1 affects the reaction [N-(1,3-benzodioxol-5-ylmethyl)-2,6-dichlorobenzamide affects the reaction [Glucose affects the phosphorylation of ULK1 protein]] CTD PMID:29128638 NCBI chr12:51,908,105...51,934,704
Ensembl chr12:51,908,448...51,934,702
JBrowse link
G Vdac1 voltage-dependent anion channel 1 multiple interactions
increases expression
ISO Triiodothyronine promotes the reaction [bafilomycin A1 results in increased expression of VDAC1 protein] CTD PMID:30209975 NCBI chr10:37,724,915...37,752,827
Ensembl chr10:37,724,915...37,752,826
JBrowse link
G Vdr vitamin D receptor multiple interactions ISO [bafilomycin A1 co-treated with Vitamin D] results in increased expression of VDR protein; [Silicon Dioxide co-treated with Vitamin D co-treated with bafilomycin A1] results in increased expression of VDR protein CTD PMID:30698894 NCBI chr 7:139,344,452...139,394,138
Ensembl chr 7:139,342,063...139,394,166
JBrowse link
G Vim vimentin multiple interactions
increases expression
ISO bafilomycin A1 promotes the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of VIM protein]
bafilomycin A1 results in increased expression of VIM protein
CTD PMID:32645460 NCBI chr17:80,882,715...80,891,200
Ensembl chr17:80,882,666...80,891,212
JBrowse link
beauvericin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aatf apoptosis antagonizing transcription factor decreases expression ISO beauvericin results in decreased expression of AATF mRNA CTD PMID:29203277 NCBI chr10:71,744,648...71,837,851
Ensembl chr10:71,744,659...71,837,851
JBrowse link
G Abca1 ATP binding cassette subfamily A member 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of ABCA1 mRNA CTD PMID:31100301 NCBI chr 5:69,857,717...69,983,042
Ensembl chr 5:69,857,771...69,983,015
JBrowse link
G Abcg1 ATP binding cassette subfamily G member 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of ABCG1 mRNA CTD PMID:31100301 NCBI chr20:9,743,269...9,842,735
Ensembl chr20:9,743,269...9,840,489
JBrowse link
G Acat2 acetyl-CoA acetyltransferase 2 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of ACAT2 protein CTD PMID:32407736 NCBI chr 1:47,972,399...47,992,654
Ensembl chr 1:47,972,399...47,992,653
JBrowse link
G Acin1 apoptotic chromatin condensation inducer 1 decreases expression ISO beauvericin results in decreased expression of ACIN1 mRNA CTD PMID:29203277 NCBI chr15:33,288,369...33,333,256
Ensembl chr15:33,288,374...33,333,417
JBrowse link
G Acsl4 acyl-CoA synthetase long-chain family member 4 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of ACSL4 protein CTD PMID:32407736 NCBI chr  X:113,596,247...113,660,024
Ensembl chr  X:113,596,239...113,659,944
JBrowse link
G Actb actin, beta decreases expression ISO beauvericin results in decreased expression of ACTB mRNA CTD PMID:29203277 NCBI chr12:13,715,843...13,718,813
Ensembl chr12:13,715,843...13,718,841
JBrowse link
G Aen apoptosis enhancing nuclease decreases expression ISO beauvericin results in decreased expression of AEN mRNA CTD PMID:29203277 NCBI chr 1:140,584,328...140,593,749
Ensembl chr 1:140,584,380...140,593,745
JBrowse link
G Aifm1 apoptosis inducing factor, mitochondria associated 1 decreases expression ISO beauvericin results in decreased expression of AIFM1 mRNA CTD PMID:29203277 NCBI chr  X:135,304,063...135,343,062
Ensembl chr  X:135,304,066...135,343,087
JBrowse link
G Ak4 adenylate kinase 4 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of AK4 mRNA CTD PMID:31100301 NCBI chr 5:120,250,318...120,309,153
Ensembl chr 5:120,250,616...120,305,897
JBrowse link
G Aldh5a1 aldehyde dehydrogenase 5 family, member A1 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of ALDH5A1 protein CTD PMID:32407736 NCBI chr17:42,133,076...42,159,413
Ensembl chr17:42,133,076...42,159,413
JBrowse link
G Aldoa aldolase, fructose-bisphosphate A decreases expression ISO beauvericin results in decreased expression of ALDOA mRNA CTD PMID:29203277 NCBI chr 1:198,228,387...198,233,988
Ensembl chr 1:198,228,387...198,233,588
JBrowse link
G Anapc13 anaphase promoting complex subunit 13 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of ANAPC13 protein CTD PMID:32407736 NCBI chr 8:111,107,358...111,115,774
Ensembl chr 8:111,107,358...111,115,774
JBrowse link
G Aprt adenine phosphoribosyl transferase decreases expression ISO beauvericin results in decreased expression of APRT mRNA CTD PMID:29203277 NCBI chr19:55,387,288...55,389,256
Ensembl chr19:55,387,288...55,389,256
JBrowse link
G Ar androgen receptor multiple interactions ISO beauvericin inhibits the reaction [Dihydrotestosterone results in increased expression of AR mRNA] CTD PMID:30716354 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
JBrowse link
G Arhgdia Rho GDP dissociation inhibitor alpha decreases expression ISO beauvericin results in decreased expression of ARHGDIA mRNA CTD PMID:29203277 NCBI chr10:109,754,012...109,757,506
Ensembl chr10:109,754,004...109,757,550
JBrowse link
G Arpp21 cAMP regulated phosphoprotein 21 increases expression ISO beauvericin results in increased expression of ARPP21 mRNA CTD PMID:29203277 NCBI chr 8:120,323,895...120,492,790
Ensembl chr 8:120,323,897...120,446,507
JBrowse link
G Atp1a1 ATPase Na+/K+ transporting subunit alpha 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of ATP1A1 protein CTD PMID:32407736 NCBI chr 2:204,003,742...204,032,023
Ensembl chr 2:204,003,742...204,032,023
JBrowse link
G Atp1a3 ATPase Na+/K+ transporting subunit alpha 3 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of ATP1A3 protein CTD PMID:32407736 NCBI chr 1:81,852,423...81,881,565
Ensembl chr 1:81,852,429...81,881,549
JBrowse link
G Atp5pb ATP synthase peripheral stalk-membrane subunit b multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of ATP5PB protein CTD PMID:32407736 NCBI chr 2:208,566,385...208,577,147
Ensembl chr 2:208,566,385...208,577,146
JBrowse link
G Atp5pf ATP synthase peripheral stalk subunit F6 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of ATP5PF protein CTD PMID:32407736 NCBI chr11:24,286,806...24,294,419
Ensembl chr11:24,286,787...24,294,179
JBrowse link
G Bax BCL2 associated X, apoptosis regulator decreases expression ISO beauvericin results in decreased expression of BAX mRNA CTD PMID:29203277 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcl2 BCL2, apoptosis regulator increases expression ISO beauvericin results in increased expression of BCL2 mRNA CTD PMID:29203277 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Birc2 baculoviral IAP repeat-containing 2 increases expression ISO beauvericin results in increased expression of BIRC2 mRNA CTD PMID:29203277 NCBI chr 8:6,014,014...6,036,668
Ensembl chr 8:6,013,207...6,034,142
JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 increases expression ISO beauvericin results in increased expression of BIRC3 mRNA CTD PMID:29203277 NCBI chr 8:6,048,590...6,076,828
Ensembl chr 8:6,048,969...6,076,598
JBrowse link
G Btf3l4 basic transcription factor 3-like 4 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of BTF3L4 protein CTD PMID:32407736 NCBI chr 5:128,432,049...128,450,530
Ensembl chr 5:128,432,433...128,446,725
JBrowse link
G C1qtnf3 C1q and TNF related 3 decreases expression ISO beauvericin results in decreased expression of C1QTNF3 mRNA CTD PMID:29203277 NCBI chr 2:60,920,160...60,942,586
Ensembl chr 2:60,920,257...60,942,500
JBrowse link
G C1qtnf6 C1q and TNF related 6 increases expression ISO beauvericin results in increased expression of C1QTNF6 mRNA CTD PMID:29203277 NCBI chr 7:119,746,150...119,752,727
Ensembl chr 7:119,746,118...119,753,290
JBrowse link
G Caap1 caspase activity and apoptosis inhibitor 1 decreases expression ISO beauvericin results in decreased expression of CAAP1 mRNA CTD PMID:29203277 NCBI chr 5:113,479,416...113,532,961
Ensembl chr 5:113,480,547...113,532,878
JBrowse link
G Card11 caspase recruitment domain family, member 11 decreases expression ISO beauvericin results in decreased expression of CARD11 mRNA CTD PMID:29203277 NCBI chr12:15,700,600...15,844,512
Ensembl chr12:15,700,825...15,844,512
JBrowse link
G Casp3 caspase 3 increases activity EXP beauvericin results in increased activity of CASP3 protein CTD PMID:25178661 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp7 caspase 7 increases activity EXP beauvericin results in increased activity of CASP7 protein CTD PMID:25178661 NCBI chr 1:277,190,557...277,242,779
Ensembl chr 1:277,190,964...277,242,774
JBrowse link
G Casp8 caspase 8 increases expression ISO beauvericin results in increased expression of CASP8 mRNA CTD PMID:29203277 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Casp9 caspase 9 increases expression ISO beauvericin results in increased expression of CASP9 mRNA CTD PMID:29203277 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Ccar2 cell cycle and apoptosis regulator 2 decreases expression ISO beauvericin results in decreased expression of CCAR2 mRNA CTD PMID:29203277 NCBI chr15:51,818,887...51,834,443
Ensembl chr15:51,818,897...51,834,030
JBrowse link
G Ccdc124 coiled-coil domain containing 124 decreases expression ISO beauvericin results in decreased expression of CCDC124 mRNA CTD PMID:29203277 NCBI chr16:20,317,446...20,323,265
Ensembl chr16:20,317,446...20,323,265
JBrowse link
G Ccdc180 coiled-coil domain containing 180 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of CCDC180 protein CTD PMID:32407736 NCBI chr 5:61,467,799...61,542,675
Ensembl chr 5:61,474,000...61,542,653
JBrowse link
G Ccdc86 coiled-coil domain containing 86 decreases expression ISO beauvericin results in decreased expression of CCDC86 mRNA CTD PMID:29203277 NCBI chr 1:226,996,435...227,002,016
Ensembl chr 1:226,996,237...227,002,139
JBrowse link
G Ccng2 cyclin G2 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of CCNG2 mRNA CTD PMID:31100301 NCBI chr14:16,267,572...16,276,068
Ensembl chr14:16,267,573...16,276,068
JBrowse link
G Cct5 chaperonin containing TCP1 subunit 5 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of CCT5 protein CTD PMID:32407736 NCBI chr 2:84,667,578...84,678,730
Ensembl chr 2:84,667,633...84,678,790
JBrowse link
G Cd47 Cd47 molecule multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of CD47 protein CTD PMID:32407736 NCBI chr11:53,511,485...53,575,754
Ensembl chr11:53,514,595...53,575,175
JBrowse link
G Cd81 Cd81 molecule multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of CD81 protein CTD PMID:32407736 NCBI chr 1:216,237,663...216,253,460
Ensembl chr 1:216,237,697...216,253,311
JBrowse link
G Cdk2ap2 cyclin-dependent kinase 2 associated protein 2 decreases expression ISO beauvericin results in decreased expression of CDK2AP2 mRNA CTD PMID:29203277 NCBI chr 1:219,345,638...219,347,709
Ensembl chr 1:219,345,918...219,347,728
JBrowse link
G Cebpb CCAAT/enhancer binding protein beta multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of CEBPB mRNA CTD PMID:31100301 NCBI chr 3:164,424,502...164,425,933
Ensembl chr 3:164,424,515...164,425,910
JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator increases expression ISO beauvericin results in increased expression of CFLAR mRNA CTD PMID:29203277 NCBI chr 9:65,534,608...65,586,395
Ensembl chr 9:65,534,704...65,587,251
JBrowse link
G Chchd2 coiled-coil-helix-coiled-coil-helix domain containing 2 decreases expression ISO beauvericin results in decreased expression of CHCHD2 mRNA CTD PMID:29203277 NCBI chr 9:101,388,148...101,388,819
Ensembl chr 9:101,388,151...101,388,833
JBrowse link
G Ciapin1 cytokine induced apoptosis inhibitor 1 decreases expression ISO beauvericin results in decreased expression of CIAPIN1 mRNA CTD PMID:29203277 NCBI chr19:10,596,923...10,612,414
Ensembl chr19:10,596,960...10,610,049
JBrowse link
G Cnp 2',3'-cyclic nucleotide 3' phosphodiesterase multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of CNP protein CTD PMID:32407736 NCBI chr10:88,490,798...88,497,357
Ensembl chr10:88,490,798...88,497,356
JBrowse link
G Coa6 cytochrome c oxidase assembly factor 6 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of COA6 protein CTD PMID:32407736 NCBI chr19:59,327,328...59,333,706
Ensembl chr19:59,328,960...59,331,192
JBrowse link
G Coro1c coronin 1C multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of CORO1C protein CTD PMID:32407736 NCBI chr12:48,481,741...48,554,054
Ensembl chr12:48,481,750...48,554,052
JBrowse link
G Cotl1 coactosin-like F-actin binding protein 1 decreases expression ISO beauvericin results in decreased expression of COTL1 mRNA CTD PMID:29203277 NCBI chr19:52,465,074...52,499,433
Ensembl chr19:52,465,087...52,499,433
JBrowse link
G Cplane2 ciliogenesis and planar polarity effector 2 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of CPLANE2 protein CTD PMID:32407736 NCBI chr 5:159,735,008...159,735,956
Ensembl chr 5:159,734,838...159,742,774
JBrowse link
G Cpne1 copine 1 decreases expression ISO beauvericin results in decreased expression of CPNE1 mRNA CTD PMID:29203277 NCBI chr 3:151,617,733...151,625,448
NCBI chr 3:152,150,143...152,192,936
Ensembl chr 3:151,616,037...151,625,644
Ensembl chr 3:151,616,037...151,625,644
JBrowse link
G Crim1 cysteine rich transmembrane BMP regulator 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of CRIM1 mRNA CTD PMID:31100301 NCBI chr 6:788,490...962,663
Ensembl chr 6:788,548...960,703
JBrowse link
G Csdc2 cold shock domain containing C2 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of CSDC2 protein CTD PMID:32407736 NCBI chr 7:123,168,811...123,183,336
Ensembl chr 7:123,168,811...123,183,335
JBrowse link
G Csk C-terminal Src kinase decreases expression ISO beauvericin results in decreased expression of CSK mRNA CTD PMID:29203277 NCBI chr 8:62,405,714...62,424,707
Ensembl chr 8:62,405,715...62,424,303
JBrowse link
G Ctps1 CTP synthase 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of CTPS1 protein CTD PMID:32407736 NCBI chr 5:139,475,934...139,505,065
Ensembl chr 5:139,475,934...139,505,065
JBrowse link
G Ctsd cathepsin D multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of CTSD protein CTD PMID:32407736 NCBI chr 1:215,541,570...215,553,446
Ensembl chr 1:215,541,542...215,553,451
JBrowse link
G Cyp4f39 cytochrome P450, family 4, subfamily f, polypeptide 39 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of CYP4F22 protein CTD PMID:32407736 NCBI chr 7:14,435,024...14,514,960
Ensembl chr 7:14,441,476...14,515,212
JBrowse link
G Dcxr dicarbonyl and L-xylulose reductase multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of DCXR protein CTD PMID:32407736 NCBI chr10:109,906,119...109,909,696
Ensembl chr10:109,906,815...109,909,715
JBrowse link
G Ddias DNA damage-induced apoptosis suppressor decreases expression ISO beauvericin results in decreased expression of DDIAS mRNA CTD PMID:29203277 NCBI chr 1:157,675,754...157,700,064
Ensembl chr 1:157,675,765...157,700,064
JBrowse link
G Ddx47 DEAD-box helicase 47 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of DDX47 protein CTD PMID:32407736 NCBI chr 4:168,775,134...168,787,594
Ensembl chr 4:168,775,111...168,787,730
JBrowse link
G Dhrs7 dehydrogenase/reductase 7 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of DHRS7 protein CTD PMID:32407736 NCBI chr 6:95,522,577...95,541,393
Ensembl chr 6:95,522,577...95,541,393
JBrowse link
G Edem1 ER degradation enhancing alpha-mannosidase like protein 1 increases expression ISO beauvericin results in increased expression of EDEM1 mRNA CTD PMID:29203277 NCBI chr 4:140,886,644...140,918,654
Ensembl chr 4:140,886,545...140,915,779
JBrowse link
G Eif5a eukaryotic translation initiation factor 5A decreases expression ISO beauvericin results in decreased expression of EIF5A mRNA CTD PMID:29203277 NCBI chr10:56,527,075...56,531,615
Ensembl chr10:56,527,085...56,531,483
JBrowse link
G Faim2 Fas apoptotic inhibitory molecule 2 increases expression ISO beauvericin results in increased expression of FAIM2 mRNA CTD PMID:29203277 NCBI chr 7:141,158,769...141,185,781
Ensembl chr 7:141,157,963...141,185,710
JBrowse link
G Fmc1 formation of mitochondrial complex V assembly factor 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of FMC1 protein CTD PMID:32407736 NCBI chr 4:66,276,835...66,284,868
Ensembl chr 4:66,276,835...66,284,868
JBrowse link
G Gaa glucosidase, alpha, acid multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of GAA protein CTD PMID:32407736 NCBI chr10:108,395,873...108,412,999
Ensembl chr10:108,395,860...108,413,059
JBrowse link
G Gna14 G protein subunit alpha 14 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of GNA14 protein CTD PMID:32407736 NCBI chr 1:235,165,775...235,347,986
Ensembl chr 1:235,166,718...235,347,937
JBrowse link
G Gnai3 G protein subunit alpha i3 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of GNAI3 protein CTD PMID:32407736 NCBI chr 2:210,896,779...210,934,733
Ensembl chr 2:210,896,656...210,934,749
JBrowse link
G Gnb1 G protein subunit beta 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of GNB1 protein CTD PMID:32407736 NCBI chr 5:172,914,025...172,981,403
Ensembl chr 5:172,934,990...172,979,986
JBrowse link
G Golga1 golgin A1 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of GOLGA1 protein CTD PMID:32407736 NCBI chr 3:23,309,318...23,353,439
Ensembl chr 3:23,309,318...23,353,425
JBrowse link
G Gpnmb glycoprotein nmb multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of GPNMB protein CTD PMID:32407736 NCBI chr 4:78,694,447...78,715,685
Ensembl chr 4:78,694,447...78,715,683
JBrowse link
G Gpr18 G protein-coupled receptor 18 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of GPR18 mRNA CTD PMID:31100301 NCBI chr15:108,323,157...108,326,907
Ensembl chr15:108,323,179...108,326,907
JBrowse link
G Hexb hexosaminidase subunit beta multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of HEXB protein CTD PMID:32407736 NCBI chr 2:27,983,925...28,003,260
Ensembl chr 2:27,984,117...28,003,186
JBrowse link
G Hist2h2be histone cluster 2 H2B family member E multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of HIST2H2BE protein CTD PMID:32407736 NCBI chr 2:198,360,837...198,363,399
Ensembl chr 2:198,360,998...198,361,378
JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of HMGCS1 mRNA CTD PMID:31100301 NCBI chr 2:52,427,351...52,445,082
Ensembl chr 2:52,431,601...52,445,055
JBrowse link
G Hnrnpm heterogeneous nuclear ribonucleoprotein M multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of HNRNPM protein CTD PMID:32407736 NCBI chr 7:18,516,253...18,554,536
Ensembl chr 7:18,516,512...18,554,227
JBrowse link
G Hnrnpu heterogeneous nuclear ribonucleoprotein U multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of HNRNPU protein CTD PMID:32407736 NCBI chr13:96,222,093...96,238,845
Ensembl chr13:96,225,912...96,238,572
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of HSPA5 mRNA CTD PMID:31100301 NCBI chr 3:13,838,304...13,842,763
Ensembl chr 3:13,838,304...13,842,762
JBrowse link
G Immt inner membrane mitochondrial protein multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of IMMT protein CTD PMID:32407736 NCBI chr 4:99,753,446...99,789,921
Ensembl chr 4:99,753,500...99,792,484
JBrowse link
G Insig1 insulin induced gene 1 increases expression ISO beauvericin results in increased expression of INSIG1 mRNA CTD PMID:29203277 NCBI chr 4:342,302...350,515
Ensembl chr 4:342,302...350,515
JBrowse link
G Islr2 immunoglobulin superfamily containing leucine-rich repeat 2 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of ISLR2 protein CTD PMID:32407736 NCBI chr 8:62,983,333...62,991,401
Ensembl chr 8:62,984,552...62,987,182
JBrowse link
G Itgb1 integrin subunit beta 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of ITGB1 protein CTD PMID:32407736 NCBI chr19:61,677,512...61,725,537
Ensembl chr19:61,677,542...61,725,535
JBrowse link
G Klf12 Kruppel-like factor 12 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of KLF12 protein CTD PMID:32407736 NCBI chr15:84,316,986...84,748,549
Ensembl chr15:84,324,470...84,748,525
JBrowse link
G Kpnb1 karyopherin subunit beta 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of KPNB1 protein CTD PMID:32407736 NCBI chr10:85,096,517...85,124,641
Ensembl chr10:85,093,841...85,124,644
JBrowse link
G Krt16 keratin 16 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of KRT16 protein CTD PMID:32407736 NCBI chr10:88,149,210...88,152,167
Ensembl chr10:88,149,345...88,152,064
JBrowse link
G Krt27 keratin 27 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of KRT27 protein CTD PMID:32407736 NCBI chr10:87,256,434...87,261,717
Ensembl chr10:87,256,434...87,261,717
JBrowse link
G Krt5 keratin 5 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of KRT5 protein CTD PMID:32407736 NCBI chr 7:143,320,142...143,324,536
Ensembl chr 7:143,316,920...143,453,546
JBrowse link
G Krt76 keratin 76 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of KRT76 protein CTD PMID:32407736 NCBI chr 7:143,488,668...143,497,108
Ensembl chr 7:143,488,684...143,497,108
JBrowse link
G Lamp2 lysosomal-associated membrane protein 2 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of LAMP2 protein CTD PMID:32407736 NCBI chr  X:124,722,628...124,766,079
Ensembl chr  X:124,722,628...124,766,044
JBrowse link
G Lat linker for activation of T cells decreases expression ISO beauvericin results in decreased expression of LAT mRNA CTD PMID:29203277 NCBI chr 1:197,765,644...197,770,669
Ensembl chr 1:197,765,644...197,770,669
JBrowse link
G LOC100909664 centrosomal protein of 170 kDa-like multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of CEP170P1 protein CTD PMID:32407736 NCBI chr13:43,806,605...43,845,197
Ensembl chr13:43,818,010...43,845,101
JBrowse link
G Mapk1 mitogen activated protein kinase 1 decreases phosphorylation EXP beauvericin results in decreased phosphorylation of MAPK1 protein CTD PMID:25178661 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 decreases phosphorylation EXP beauvericin results in decreased phosphorylation of MAPK3 protein CTD PMID:25178661 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Matn4 matrilin 4 decreases expression ISO beauvericin results in decreased expression of MATN4 mRNA CTD PMID:29203277 NCBI chr 3:160,838,632...160,853,650
Ensembl chr 3:160,838,632...160,853,650
JBrowse link
G Mavs mitochondrial antiviral signaling protein increases expression ISO beauvericin results in increased expression of MAVS mRNA CTD PMID:29203277 NCBI chr 3:123,776,147...123,790,572
Ensembl chr 3:123,776,181...123,790,567
JBrowse link
G Med6 mediator complex subunit 6 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of MED6 protein CTD PMID:32407736 NCBI chr 6:105,302,558...105,316,024
Ensembl chr 6:105,302,558...105,316,024
JBrowse link
G Moap1 modulator of apoptosis 1 increases expression ISO beauvericin results in increased expression of MOAP1 mRNA CTD PMID:29203277 NCBI chr 6:126,620,597...126,622,532
Ensembl chr 6:126,620,602...126,622,532
JBrowse link
G Mrpl12 mitochondrial ribosomal protein L12 decreases expression
multiple interactions
ISO beauvericin results in decreased expression of MRPL12 mRNA
[beauvericin co-treated with enniatins] results in decreased expression of MRPL12 mRNA
CTD PMID:29203277, PMID:31100301 NCBI chr10:109,658,032...109,662,535
Ensembl chr10:109,658,032...109,662,535
JBrowse link
G Mrpl4 mitochondrial ribosomal protein L4 decreases expression ISO beauvericin results in decreased expression of MRPL4 mRNA CTD PMID:29203277 NCBI chr 8:22,021,213...22,027,228
Ensembl chr 8:22,021,213...22,027,228
JBrowse link
G Mt-atp6 mitochondrially encoded ATP synthase membrane subunit 6 decreases expression
multiple interactions
ISO beauvericin results in decreased expression of ATP6 mRNA
[beauvericin co-treated with enniatins] results in increased expression of ATP6 mRNA
CTD PMID:29203277, PMID:31100301 NCBI chr MT:7,919...8,599
Ensembl chr MT:7,919...8,599
JBrowse link
G Mt-atp8 mitochondrially encoded ATP synthase membrane subunit 8 decreases expression
multiple interactions
ISO beauvericin results in decreased expression of ATP8 mRNA
[beauvericin co-treated with enniatins] affects the expression of ATP8 mRNA
CTD PMID:29203277, PMID:31100301 NCBI chr MT:7,758...7,961
Ensembl chr MT:7,758...7,961
JBrowse link
G Mt-co1 mitochondrially encoded cytochrome c oxidase I multiple interactions
decreases expression
ISO [beauvericin co-treated with enniatins] affects the expression of COX1 mRNA
beauvericin results in decreased expression of COX1 mRNA
CTD PMID:31100301 NCBI chr MT:5,323...6,867
Ensembl chr MT:5,323...6,867
JBrowse link
G Mt-co3 mitochondrially encoded cytochrome c oxidase III decreases expression ISO beauvericin results in decreased expression of COX3 mRNA CTD PMID:29203277, PMID:31100301 NCBI chr MT:8,599...9,382
Ensembl chr MT:8,599...9,382
JBrowse link
G Mt-cyb mitochondrially encoded cytochrome b decreases expression ISO beauvericin results in decreased expression of CYTB mRNA CTD PMID:29203277 NCBI chr MT:14,136...15,278
Ensembl chr MT:14,136...15,278
JBrowse link
G Mt-nd2 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 2 decreases expression
multiple interactions
ISO beauvericin results in decreased expression of ND2 mRNA
[beauvericin co-treated with enniatins] results in decreased expression of ND2 mRNA
CTD PMID:29203277, PMID:31100301 NCBI chr MT:3,904...4,942
Ensembl chr MT:3,904...4,942
JBrowse link
G Mt-nd3 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 3 decreases expression
multiple interactions
ISO beauvericin results in decreased expression of ND3 mRNA
[beauvericin co-treated with enniatins] results in increased expression of ND3 mRNA
CTD PMID:29203277, PMID:31100301 NCBI chr MT:9,451...9,798
Ensembl chr MT:9,451...9,798
JBrowse link
G Mt-nd4 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 4 decreases expression
multiple interactions
ISO beauvericin results in decreased expression of ND4 mRNA
[beauvericin co-treated with enniatins] results in increased expression of ND4 mRNA
CTD PMID:29203277, PMID:31100301 NCBI chr MT:10,160...11,537
Ensembl chr MT:10,160...11,537
JBrowse link
G Mt-nd4l mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 4L decreases expression ISO beauvericin results in decreased expression of ND4L mRNA CTD PMID:29203277, PMID:31100301 NCBI chr MT:9,870...10,166
Ensembl chr MT:9,870...10,166
JBrowse link
G Mt-nd5 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 5 decreases expression
multiple interactions
ISO beauvericin results in decreased expression of ND5 mRNA
[beauvericin co-treated with enniatins] results in decreased expression of ND5 mRNA
CTD PMID:29203277, PMID:31100301 NCBI chr MT:11,736...13,565
Ensembl chr MT:11,736...13,565
JBrowse link
G Mtrf1l mitochondrial translational release factor 1-like multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of MTRF1L protein CTD PMID:32407736 NCBI chr 1:42,475,791...42,485,999
Ensembl chr 1:42,475,792...42,486,035
JBrowse link
G Nars1 asparaginyl-tRNA synthetase 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of NARS1 protein CTD PMID:32407736 NCBI chr18:59,986,350...60,002,644
Ensembl chr18:59,986,360...60,002,569
JBrowse link
G Nars2 asparaginyl-tRNA synthetase 2, mitochondrial multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of NARS2 protein CTD PMID:32407736 NCBI chr 1:161,922,132...162,035,817
Ensembl chr 1:161,922,141...162,034,700
JBrowse link
G Ndrg1 N-myc downstream regulated 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of NDRG1 protein CTD PMID:32407736 NCBI chr 7:107,734,326...107,775,701
Ensembl chr 7:107,734,323...107,775,714
JBrowse link
G Nlrp1a NLR family, pyrin domain containing 1A increases expression ISO beauvericin results in increased expression of NLRP1 mRNA CTD PMID:29203277 NCBI chr10:57,692,474...57,747,608
Ensembl chr10:57,692,474...57,822,498
JBrowse link
G Nod1 nucleotide-binding oligomerization domain containing 1 increases expression ISO beauvericin results in increased expression of NOD1 mRNA CTD PMID:29203277 NCBI chr 4:85,123,965...85,175,206
Ensembl chr 4:85,123,960...85,174,951
JBrowse link
G Nol3 nucleolar protein 3 increases expression ISO beauvericin results in increased expression of NOL3 mRNA CTD PMID:29203277 NCBI chr19:37,232,567...37,236,668
Ensembl chr19:37,235,001...37,236,649
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of NQO1 mRNA CTD PMID:31100301 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Nudt1 nudix hydrolase 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of NUDT1 protein CTD PMID:32407736 NCBI chr12:16,391,578...16,398,771
Ensembl chr12:16,391,578...16,395,029
JBrowse link
G Oga O-GlcNAcase increases expression ISO beauvericin results in increased expression of OGA mRNA CTD PMID:29203277 NCBI chr 1:265,506,752...265,542,452
Ensembl chr 1:265,507,451...265,542,276
JBrowse link
G Ogt O-linked N-acetylglucosamine (GlcNAc) transferase increases expression ISO beauvericin results in increased expression of OGT mRNA CTD PMID:29203277 NCBI chr  X:71,540,870...71,585,906
Ensembl chr  X:71,528,988...71,585,908
JBrowse link
G Osgin1 oxidative stress induced growth inhibitor 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of OSGIN1 mRNA CTD PMID:31100301 NCBI chr19:52,056,808...52,085,491
Ensembl chr19:52,077,109...52,085,496
JBrowse link
G Ostc oligosaccharyltransferase complex non-catalytic subunit multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of OSTC protein CTD PMID:32407736 NCBI chr 2:235,816,328...235,831,651
Ensembl chr 2:235,816,336...235,831,670
JBrowse link
G Parvg parvin, gamma multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of PARVG protein CTD PMID:32407736 NCBI chr 7:125,288,081...125,307,587
Ensembl chr 7:125,288,081...125,306,976
JBrowse link
G Pawr pro-apoptotic WT1 regulator decreases expression ISO beauvericin results in decreased expression of PAWR mRNA CTD PMID:29203277 NCBI chr 7:51,273,764...51,353,700
Ensembl chr 7:51,273,771...51,353,068
JBrowse link
G Pdcd11 programmed cell death 11 decreases expression ISO beauvericin results in decreased expression of PDCD11 mRNA CTD PMID:29203277 NCBI chr 1:266,866,931...266,908,042
Ensembl chr 1:266,866,931...266,908,042
JBrowse link
G Pdcd2 programmed cell death 2 decreases expression ISO beauvericin results in decreased expression of PDCD2 mRNA CTD PMID:29203277 NCBI chr 1:57,512,968...57,518,458
Ensembl chr 1:57,512,968...57,518,458
JBrowse link
G Pdcd2l programmed cell death 2-like increases expression ISO beauvericin results in increased expression of PDCD2L mRNA CTD PMID:29203277 NCBI chr 1:90,045,468...90,057,756
Ensembl chr 1:90,045,509...90,057,923
JBrowse link
G Pdcd4 programmed cell death 4 decreases expression ISO beauvericin results in decreased expression of PDCD4 mRNA CTD PMID:29203277 NCBI chr 1:274,616,625...274,648,204
Ensembl chr 1:274,625,224...274,648,204
JBrowse link
G Pdcd5 programmed cell death 5 increases expression ISO beauvericin results in increased expression of PDCD5 mRNA CTD PMID:29203277 NCBI chr 1:91,173,473...91,178,801
Ensembl chr 1:91,173,473...91,178,801
Ensembl chr 1:91,173,473...91,178,801
JBrowse link
G Pdcd6ip programmed cell death 6 interacting protein increases expression ISO beauvericin results in increased expression of PDCD6IP mRNA CTD PMID:29203277 NCBI chr 8:121,916,233...121,973,145
Ensembl chr 8:121,916,185...121,973,125
JBrowse link
G Pdia4 protein disulfide isomerase family A, member 4 decreases expression ISO beauvericin results in decreased expression of PDIA4 mRNA CTD PMID:29203277 NCBI chr 4:77,470,636...77,489,535
Ensembl chr 4:77,470,636...77,489,535
JBrowse link
G Pfn1 profilin 1 decreases expression
multiple interactions
ISO beauvericin results in decreased expression of PFN1 mRNA
[beauvericin co-treated with enniatins] results in increased expression of PFN1 protein
CTD PMID:29203277, PMID:32407736 NCBI chr10:57,273,003...57,275,708
Ensembl chr10:57,273,005...57,275,708
JBrowse link
G Pgam1 phosphoglycerate mutase 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of PGAM1 protein CTD PMID:32407736 NCBI chr 1:261,158,204...261,165,814
Ensembl chr 1:261,158,261...261,165,808
JBrowse link
G Pgk1 phosphoglycerate kinase 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of PGK1 protein CTD PMID:32407736 NCBI chr  X:77,263,399...77,279,373
Ensembl chr  X:77,263,359...77,279,367
JBrowse link
G Phgdh phosphoglycerate dehydrogenase multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of PHGDH protein CTD PMID:32407736 NCBI chr 2:200,484,245...200,513,564
Ensembl chr 2:200,484,246...200,513,564
JBrowse link
G Phka2 phosphorylase kinase regulatory subunit alpha 2 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of PHKA2 protein CTD PMID:32407736 NCBI chr  X:35,970,650...36,926,616 JBrowse link
G Pidd1 p53-induced death domain protein 1 decreases expression ISO beauvericin results in decreased expression of PIDD1 mRNA CTD PMID:29203277 NCBI chr 1:214,418,751...214,423,959
Ensembl chr 1:214,419,240...214,423,881
JBrowse link
G Plk1 polo-like kinase 1 decreases expression ISO beauvericin results in decreased expression of PLK1 mRNA CTD PMID:29203277 NCBI chr 1:192,115,990...192,125,969
Ensembl chr 1:192,115,966...192,125,989
JBrowse link
G Pls3 plastin 3 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of PLS3 protein CTD PMID:32407736 NCBI chr  X:119,030,311...119,124,268
Ensembl chr  X:119,030,419...119,124,250
JBrowse link
G Ppa1 inorganic pyrophosphatase 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of PPA1 protein CTD PMID:32407736 NCBI chr20:31,265,519...31,292,451
Ensembl chr20:31,265,483...31,310,674
JBrowse link
G Ppan peter pan homolog decreases expression ISO beauvericin results in decreased expression of PPAN mRNA CTD PMID:29203277 NCBI chr 8:21,905,865...21,909,845
Ensembl chr 8:21,905,865...21,909,842
JBrowse link
G Ppib peptidylprolyl isomerase B decreases expression ISO beauvericin results in decreased expression of PPIB mRNA CTD PMID:29203277 NCBI chr 8:71,719,681...71,725,538
Ensembl chr 8:71,719,563...71,725,562
JBrowse link
G Ppp1r14b protein phosphatase 1, regulatory (inhibitor) subunit 14B decreases expression ISO beauvericin results in decreased expression of PPP1R14B mRNA CTD PMID:29203277 NCBI chr 1:222,229,835...222,231,945
Ensembl chr 1:222,229,835...222,231,944
JBrowse link
G Ppt1 palmitoyl-protein thioesterase 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of PPT1 protein CTD PMID:32407736 NCBI chr 5:140,538,260...140,558,163
Ensembl chr 5:140,538,260...140,558,162
JBrowse link
G Prkca protein kinase C, alpha multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of PRKCA protein CTD PMID:32407736 NCBI chr10:96,186,509...96,585,168
Ensembl chr10:96,191,133...96,584,947
JBrowse link
G Psma5 proteasome 20S subunit alpha 5 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of PSMA5 protein CTD PMID:32407736 NCBI chr 2:211,050,344...211,073,706
Ensembl chr 2:211,050,360...211,073,714
JBrowse link
G Psme4 proteasome activator subunit 4 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of PSME4 protein CTD PMID:32407736 NCBI chr14:115,166,165...115,269,041
Ensembl chr14:115,166,416...115,269,056
JBrowse link
G Ptges3 prostaglandin E synthase 3 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of PTGES3 protein CTD PMID:32407736 NCBI chr 7:2,479,267...2,497,024
Ensembl chr 7:2,479,311...2,497,013
JBrowse link
G Ptprc protein tyrosine phosphatase, receptor type, C multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of PTPRC protein CTD PMID:32407736 NCBI chr13:55,061,561...55,174,150
Ensembl chr13:55,061,562...55,173,692
JBrowse link
G Rab11fip5 RAB11 family interacting protein 5 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of RAB11FIP5 protein CTD PMID:32407736 NCBI chr 4:117,113,067...117,154,495
Ensembl chr 4:117,115,076...117,153,907
JBrowse link
G Rab5a RAB5A, member RAS oncogene family multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of RAB5A protein CTD PMID:32407736 NCBI chr 9:5,910...6,065 JBrowse link
G Rac3 Rac family small GTPase 3 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of RAC3 protein CTD PMID:32407736 NCBI chr10:109,903,920...109,906,596
Ensembl chr10:109,904,259...109,906,232
JBrowse link
G Rap1a RAP1A, member of RAS oncogene family multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of RAP1A protein CTD PMID:32407736 NCBI chr 2:208,193,950...208,215,186
Ensembl chr 2:208,193,954...208,215,187
JBrowse link
G Relt RELT, TNF receptor decreases expression ISO beauvericin results in decreased expression of RELT mRNA CTD PMID:29203277 NCBI chr 1:165,884,407...165,902,022
Ensembl chr 1:165,884,407...165,901,923
JBrowse link
G Rp2 RP2 activator of ARL3 GTPase multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of RP2 protein CTD PMID:32407736 NCBI chr  X:2,066,298...2,116,661
Ensembl chr  X:2,064,486...2,116,656
JBrowse link
G Rpl37a ribosomal protein L37a multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of RPL37A protein CTD PMID:32407736 NCBI chr 9:80,002,892...80,004,995 JBrowse link
G Rpl5 ribosomal protein L5 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of RPL5 protein CTD PMID:32407736 NCBI chr14:2,860,963...2,867,397
Ensembl chr14:2,860,965...2,867,397
JBrowse link
G Rpl8 ribosomal protein L8 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of RPL8 protein CTD PMID:32407736 NCBI chr 7:117,967,608...117,969,886
Ensembl chr 7:118,507,224...118,509,256
JBrowse link
G Rxra retinoid X receptor alpha multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of RXRA protein CTD PMID:32407736 NCBI chr 3:6,272,560...6,295,354
Ensembl chr 3:6,211,789...6,295,908
JBrowse link
G Scml2 Scm polycomb group protein like 2 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of SCML2 protein CTD PMID:32407736 NCBI chr  X:35,305,235...35,431,271
Ensembl chr  X:35,305,236...35,431,164
JBrowse link
G Sdf2l1 stromal cell-derived factor 2-like 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of SDF2L1 protein CTD PMID:32407736 NCBI chr11:88,122,271...88,124,513
Ensembl chr11:88,122,271...88,124,513
JBrowse link
G Sdr42e2 short chain dehydrogenase/reductase family 42E, member 2 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of SDR42E2 protein CTD PMID:32407736 NCBI chr 1:190,756,747...190,769,213 JBrowse link
G Sec13 SEC13 homolog, nuclear pore and COPII coat complex component decreases expression ISO beauvericin results in decreased expression of SEC13 mRNA CTD PMID:29203277 NCBI chr 4:145,686,186...145,699,577
Ensembl chr 4:145,686,193...145,699,577
JBrowse link
G Siva1 SIVA1, apoptosis-inducing factor decreases expression ISO beauvericin results in decreased expression of SIVA1 mRNA CTD PMID:29203277 NCBI chr 6:137,209,999...137,214,379
Ensembl chr 6:137,210,052...137,214,388
JBrowse link
G Slc1a5 solute carrier family 1 member 5 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of SLC1A5 protein CTD PMID:32407736 NCBI chr 1:78,710,686...78,724,789
Ensembl chr 1:78,710,539...78,724,794
JBrowse link
G Slc2a1 solute carrier family 2 member 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of SLC2A1 protein CTD PMID:32407736 NCBI chr 5:138,154,677...138,182,897
Ensembl chr 5:138,154,673...138,182,897
JBrowse link
G Slc3a2 solute carrier family 3 member 2 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of SLC3A2 protein CTD PMID:32407736 NCBI chr 1:224,906,566...224,921,029
Ensembl chr 1:224,906,554...224,921,092
JBrowse link
G Snrpd2 small nuclear ribonucleoprotein D2 polypeptide multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of SNRPD2 protein CTD PMID:32407736 NCBI chr 1:80,057,140...80,059,990
Ensembl chr 1:80,056,755...80,059,996
JBrowse link
G Snrpd3 small nuclear ribonucleoprotein D3 polypeptide multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of SNRPD3 protein CTD PMID:32407736 NCBI chr20:14,080,562...14,095,644
Ensembl chr20:14,080,565...14,095,181
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase decreases activity EXP beauvericin results in decreased activity of SRC protein CTD PMID:25178661 NCBI chr 3:153,547,807...153,595,643
Ensembl chr 3:153,580,861...153,595,642
JBrowse link
G Srm spermidine synthase decreases expression ISO beauvericin results in decreased expression of SRM mRNA CTD PMID:29203277 NCBI chr 5:165,405,168...165,408,325
Ensembl chr 5:165,405,168...165,408,320
JBrowse link
G Srsf7 serine and arginine rich splicing factor 7 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of SRSF7 protein CTD PMID:32407736 NCBI chr 6:2,879,312...2,886,505
Ensembl chr 6:2,880,518...2,886,465
JBrowse link
G Srxn1 sulfiredoxin 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of SRXN1 mRNA CTD PMID:31100301 NCBI chr 3:147,608,850...147,614,410
Ensembl chr 3:147,609,095...147,632,801
JBrowse link
G Ssbp1 single stranded DNA binding protein 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of SSBP1 protein CTD PMID:32407736 NCBI chr 4:68,634,844...68,645,112
Ensembl chr 4:68,634,929...68,645,172
JBrowse link
G Tbc1d2b TBC1 domain family, member 2B multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of TBC1D2B protein CTD PMID:32407736 NCBI chr 8:97,577,551...97,647,072
Ensembl chr 8:97,577,565...97,647,072
JBrowse link
G Tcn2 transcobalamin 2 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of TCN2 protein CTD PMID:32407736 NCBI chr14:84,173,992...84,189,299
Ensembl chr14:84,174,138...84,189,266
JBrowse link
G Tcp11l1 t-complex 11 like 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of TCP11L1 protein CTD PMID:32407736 NCBI chr 3:94,621,433...94,657,467
Ensembl chr 3:94,624,071...94,657,377
JBrowse link
G Tcp11l2 t-complex 11 like 2 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of TCP11L2 protein CTD PMID:32407736 NCBI chr 7:24,859,048...24,893,907
Ensembl chr 7:24,859,050...24,885,775
JBrowse link
G Thyn1 thymocyte nuclear protein 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of THYN1 protein CTD PMID:32407736 NCBI chr 8:28,045,093...28,053,974
Ensembl chr 8:28,045,093...28,054,040
JBrowse link
G Timm9 translocase of inner mitochondrial membrane 9 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of TIMM9 protein CTD PMID:32407736 NCBI chr 6:93,549,484...93,562,314
Ensembl chr 6:93,549,484...93,562,314
JBrowse link
G Tk1 thymidine kinase 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of TK1 protein CTD PMID:32407736 NCBI chr10:106,817,556...106,828,888
Ensembl chr10:106,817,601...106,828,884
JBrowse link
G Tmem263 transmembrane protein 263 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of TMEM263 protein CTD PMID:32407736 NCBI chr 7:24,647,083...24,668,381
Ensembl chr 7:24,647,083...24,668,250
JBrowse link
G Tnfsf10 TNF superfamily member 10 decreases expression ISO beauvericin results in decreased expression of TNFSF10 mRNA CTD PMID:29203277 NCBI chr 2:113,008,008...113,026,899
Ensembl chr 2:113,007,549...113,026,899
JBrowse link
G Tomm22 translocase of outer mitochondrial membrane 22 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of TOMM22 protein CTD PMID:32407736 NCBI chr 7:120,901,934...120,903,684
Ensembl chr 7:120,901,934...120,903,684
JBrowse link
G Tomm7 translocase of outer mitochondrial membrane 7 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of TOMM7 protein CTD PMID:32407736 NCBI chr 4:7,835,949...7,842,790
Ensembl chr 4:7,835,949...7,842,789
JBrowse link
G Tuba1b tubulin, alpha 1B multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of TUBA1B protein CTD PMID:32407736 NCBI chr 7:140,614,746...140,617,721
Ensembl chr 7:140,614,752...140,617,721
JBrowse link
G Tubb3 tubulin, beta 3 class III multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of TUBB3 protein CTD PMID:32407736 NCBI chr19:56,220,759...56,229,813
Ensembl chr19:56,220,755...56,229,813
JBrowse link
G Tubb4a tubulin, beta 4A class IVa multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of TUBB4A protein CTD PMID:32407736 NCBI chr 9:9,961,020...9,968,420
Ensembl chr 9:9,961,021...9,968,486
JBrowse link
G Tubb4b tubulin, beta 4B class IVb multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of TUBB4B protein CTD PMID:32407736 NCBI chr 3:2,441,585...2,444,369
Ensembl chr 3:2,441,733...2,444,281
JBrowse link
G Tubb5 tubulin, beta 5 class I multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of TUBB protein CTD PMID:32407736 NCBI chr20:3,422,448...3,426,420
Ensembl chr20:3,422,461...3,426,371
JBrowse link
G Txnip thioredoxin interacting protein increases expression ISO beauvericin results in increased expression of TXNIP mRNA CTD PMID:29203277 NCBI chr 2:198,683,168...198,686,971
Ensembl chr 2:198,683,159...198,686,974
JBrowse link
G Ucp2 uncoupling protein 2 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of UCP2 mRNA CTD PMID:31100301 NCBI chr 1:165,506,375...165,512,744
Ensembl chr 1:165,506,361...165,512,744
JBrowse link
G Ucp3 uncoupling protein 3 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of UCP3 mRNA CTD PMID:31100301 NCBI chr 1:165,482,912...165,495,895
Ensembl chr 1:165,482,155...165,496,206
JBrowse link
G Ybx1 Y box binding protein 1 decreases expression ISO beauvericin results in decreased expression of YBX1 mRNA CTD PMID:29203277 NCBI chr 5:138,319,754...138,336,721
Ensembl chr 5:138,319,762...138,336,475
JBrowse link
G Ybx3 Y box binding protein 3 decreases expression ISO beauvericin results in decreased expression of YBX3 mRNA CTD PMID:29203277 NCBI chr 4:165,606,819...165,630,041
Ensembl chr 4:165,606,819...165,630,118
JBrowse link
G Ykt6 YKT6 v-SNARE homolog multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of YKT6 protein CTD PMID:32407736 NCBI chr14:86,196,018...86,207,057
Ensembl chr14:86,195,892...86,205,712
JBrowse link
carbonyl cyanide p-trifluoromethoxyphenylhydrazone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agt angiotensinogen multiple interactions EXP [Egtazic Acid co-treated with Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone] inhibits the reaction [AGT protein results in increased abundance of Reactive Oxygen Species] CTD PMID:18854758 NCBI chr19:57,321,594...57,333,460
Ensembl chr19:57,321,640...57,333,433
JBrowse link
G Akt1 AKT serine/threonine kinase 1 increases phosphorylation ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in increased phosphorylation of AKT1 protein CTD PMID:19901985 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Aqp9 aquaporin 9 multiple interactions ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone inhibits the reaction [AQP9 protein results in increased uptake of Lactic Acid]; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone inhibits the reaction [AQP9 protein results in increased uptake of Selenious Acid] CTD PMID:28798983 NCBI chr 8:77,559,621...77,599,781
Ensembl chr 8:77,559,624...77,599,781
JBrowse link
G Bax BCL2 associated X, apoptosis regulator decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of BAX mRNA CTD PMID:16039398 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcl2l1 Bcl2-like 1 decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of BCL2L1 mRNA CTD PMID:16039398 NCBI chr 3:148,259,594...148,314,191
Ensembl chr 3:148,259,596...148,313,810
JBrowse link
G Casp3 caspase 3 increases activity ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in increased activity of CASP3 protein CTD PMID:20683024 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp8 caspase 8 decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of CASP8 mRNA CTD PMID:16039398 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Cat catalase decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of CAT mRNA CTD PMID:16039398 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Ccnc cyclin C decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of CCNC mRNA CTD PMID:16039398 NCBI chr 5:35,865,598...35,883,732
Ensembl chr 5:35,865,605...35,883,706
JBrowse link
G Ccnd1 cyclin D1 decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of CCND1 mRNA CTD PMID:16039398 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Ccng1 cyclin G1 decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of CCNG1 mRNA CTD PMID:16039398 NCBI chr10:25,903,925...25,910,298
Ensembl chr10:25,903,911...25,910,325
JBrowse link
G Cdk4 cyclin-dependent kinase 4 multiple interactions ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone promotes the reaction [CDKN1B protein binds to CDK4 protein] CTD PMID:19819288 NCBI chr 7:70,345,971...70,352,689
Ensembl chr 7:70,349,863...70,352,418
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B multiple interactions
increases expression
ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone promotes the reaction [CDKN1B protein binds to CDK4 protein]
Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in increased expression of CDKN1B protein
CTD PMID:19819288 NCBI chr 4:168,689,043...168,694,159
Ensembl chr 4:168,689,163...168,693,964
JBrowse link
G Comt catechol-O-methyltransferase decreases activity
multiple interactions
ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased activity of COMT protein
[Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased activity of COMT protein] which results in decreased abundance of Adenosine Triphosphate
CTD PMID:14975680 NCBI chr11:86,715,981...86,735,630
Ensembl chr11:86,715,981...86,735,622
JBrowse link
G Coq10a coenzyme Q10A decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of COQ10A protein CTD PMID:21308897 NCBI chr 7:2,780,930...2,788,189
Ensembl chr 7:2,780,930...2,786,949
JBrowse link
G Coq2 coenzyme Q2, polyprenyltransferase increases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in increased expression of COQ2 mRNA CTD PMID:21308897 NCBI chr14:10,581,102...10,601,093
Ensembl chr14:10,581,136...10,600,566
JBrowse link
G Coq3 coenzyme Q3 methyltransferase decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of COQ3 mRNA CTD PMID:21308897 NCBI chr 5:36,024,673...36,056,664
Ensembl chr 5:36,024,649...36,056,669
JBrowse link
G Coq4 coenzyme Q4 increases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in increased expression of COQ4 mRNA CTD PMID:21308897 NCBI chr 3:8,349,386...8,357,719
Ensembl chr 3:8,349,185...8,357,871
JBrowse link
G Coq5 coenzyme Q5, methyltransferase increases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in increased expression of COQ5 mRNA CTD PMID:21308897 NCBI chr12:47,078,753...47,095,438
Ensembl chr12:47,078,753...47,095,438
JBrowse link
G Coq6 coenzyme Q6 monooxygenase increases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in increased expression of COQ6 mRNA CTD PMID:21308897 NCBI chr 6:108,076,393...108,087,782
Ensembl chr 6:108,076,306...108,087,696
JBrowse link
G Coq7 coenzyme Q7, hydroxylase increases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in increased expression of COQ7 mRNA CTD PMID:21308897 NCBI chr 1:188,176,060...188,190,874
Ensembl chr 1:188,174,874...188,190,860
JBrowse link
G Coq8a coenzyme Q8A increases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in increased expression of COQ8A mRNA CTD PMID:21308897 NCBI chr13:98,451,629...98,480,438
Ensembl chr13:98,451,637...98,480,419
JBrowse link
G Coq9 coenzyme Q9 increases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in increased expression of COQ9 mRNA CTD PMID:21308897 NCBI chr19:10,583,855...10,596,848
Ensembl chr19:10,583,857...10,596,851
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in increased expression of CYP1A1 mRNA CTD PMID:16039398 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Ddb1 damage-specific DNA binding protein 1 decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of DDB1 mRNA CTD PMID:16039398 NCBI chr 1:226,657,561...226,683,356
Ensembl chr 1:226,657,561...226,683,347
JBrowse link
G Dnaja1 DnaJ heat shock protein family (Hsp40) member A1 decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of DNAJA1 mRNA CTD PMID:16039398 NCBI chr 5:57,028,467...57,039,378
Ensembl chr 5:57,028,467...57,039,378
JBrowse link
G Egr1 early growth response 1 decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of EGR1 mRNA CTD PMID:16039398 NCBI chr18:27,657,903...27,660,101
Ensembl chr18:27,657,628...27,661,429
JBrowse link
G Ephx2 epoxide hydrolase 2 decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of EPHX2 mRNA CTD PMID:16039398 NCBI chr15:42,757,241...42,794,211
Ensembl chr15:42,757,235...42,794,279
JBrowse link
G Fmr1 FMRP translational regulator 1 multiple interactions ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone inhibits the reaction [FMR1 5' UTR mutant form results in increased abundance of Hydroxyl Radical]; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone inhibits the reaction [FMR1 5' UTR mutant form results in increased abundance of Superoxides] CTD PMID:27385396 NCBI chr  X:154,684,924...154,722,369
Ensembl chr  X:154,684,935...154,722,314
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of GADD45A mRNA CTD PMID:16039398 NCBI chr 4:97,782,512...97,784,814
Ensembl chr 4:97,782,512...97,784,842
JBrowse link
G Gdf15 growth differentiation factor 15 increases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in increased expression of GDF15 mRNA CTD PMID:16039398 NCBI chr16:20,555,395...20,557,978
Ensembl chr16:20,555,395...20,557,978
JBrowse link
G Gsr glutathione-disulfide reductase decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of GSR mRNA CTD PMID:16039398 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
JBrowse link
G Gstm3 glutathione S-transferase mu 3 decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of GSTM3 mRNA CTD PMID:16039398 NCBI chr 2:210,685,204...210,688,273
Ensembl chr 2:210,685,197...210,688,272
JBrowse link
G Gstm5 glutathione S-transferase, mu 5 decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of GSTM3 mRNA CTD PMID:16039398 NCBI chr 2:210,685,338...210,688,133
Ensembl chr 2:210,685,197...210,688,272
JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in increased expression of HMOX1 mRNA CTD PMID:16039398 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hmox2 heme oxygenase 2 decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of HMOX2 mRNA CTD PMID:16039398 NCBI chr10:10,990,034...11,035,493
Ensembl chr10:10,990,034...11,035,484
JBrowse link
G Hsf1 heat shock transcription factor 1 decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of HSF1 mRNA CTD PMID:16039398 NCBI chr 7:117,538,523...117,565,478
Ensembl chr 7:117,538,523...117,565,478
JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of HSP90AA1 mRNA CTD PMID:16039398 NCBI chr 6:135,107,262...135,112,793
Ensembl chr 6:135,107,271...135,112,775
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of HSPA1A mRNA CTD PMID:16039398 NCBI chr20:4,875,834...4,881,751
Ensembl chr20:4,877,324...4,879,779
JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of HSPA1B mRNA CTD PMID:16039398 NCBI chr20:4,877,638...4,880,112
Ensembl chr20:2,699,712...2,701,815
JBrowse link
G Hspa1l heat shock protein family A (Hsp70) member 1 like decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of HSPA1L mRNA CTD PMID:16039398 NCBI chr20:4,879,998...4,965,191
Ensembl chr20:4,959,294...4,964,963
JBrowse link
G Hspa2 heat shock protein family A (Hsp70) member 2 decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of HSPA2 mRNA CTD PMID:16039398 NCBI chr 6:99,433,575...99,436,288
Ensembl chr 6:99,433,550...99,436,289
JBrowse link
G Hspa4 heat shock protein family A (Hsp70) member 4 decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of HSPA4 mRNA CTD PMID:16039398 NCBI chr10:38,601,624...38,642,397
Ensembl chr10:38,601,624...38,642,397
JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of HSPA8 mRNA CTD PMID:16039398 NCBI chr 8:44,989,401...44,993,261
Ensembl chr 8:44,990,014...44,993,179
JBrowse link
G Hspe1 heat shock protein family E (Hsp10) member 1 increases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in increased expression of HSPE1 mRNA CTD PMID:16039398 NCBI chr 9:61,691,246...61,724,948
Ensembl chr 9:61,692,154...61,694,599
JBrowse link
G Icam1 intercellular adhesion molecule 1 decreases expression EXP Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of ICAM1 mRNA CTD PMID:17416599 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
JBrowse link
G Il18 interleukin 18 decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of IL18 mRNA CTD PMID:16039398 NCBI chr 8:55,009,666...55,016,286
Ensembl chr 8:54,993,859...55,016,299
JBrowse link
G Il1a interleukin 1 alpha decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of IL1A mRNA CTD PMID:16039398 NCBI chr 3:121,824,712...121,836,122
Ensembl chr 3:121,825,412...121,836,086
JBrowse link
G Kcnj12 potassium inwardly-rectifying channel, subfamily J, member 12 multiple interactions ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone inhibits the reaction [KCNJ12 protein results in increased transport of Potassium] CTD PMID:12118013 NCBI chr10:47,282,208...47,343,501
Ensembl chr10:47,281,786...47,341,411
JBrowse link
G Kcnj4 potassium inwardly-rectifying channel, subfamily J, member 4 multiple interactions ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone inhibits the reaction [KCNJ4 protein results in increased transport of Potassium] CTD PMID:12118013 NCBI chr 7:120,717,378...120,744,602
Ensembl chr 7:120,717,375...120,744,602
JBrowse link
G Mdm2 MDM2 proto-oncogene decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of MDM2 mRNA CTD PMID:16039398 NCBI chr 7:60,719,060...60,743,618
Ensembl chr 7:60,719,066...60,743,328
JBrowse link
G Mt1 metallothionein 1 decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of MT1A mRNA CTD PMID:16039398 NCBI chr19:11,301,991...11,303,007
Ensembl chr17:78,793,336...78,793,724
JBrowse link
G Mt2A metallothionein 2A decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of MT2A mRNA CTD PMID:16039398 NCBI chr19:11,307,966...11,308,740
Ensembl chr19:11,307,967...11,308,740
JBrowse link
G Nfkbia NFKB inhibitor alpha decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of NFKBIA mRNA CTD PMID:16039398 NCBI chr 6:76,267,227...76,270,457
Ensembl chr 6:76,267,228...76,270,457
JBrowse link
G Nipa1 NIPA magnesium transporter 1 decreases expression EXP Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of NIPA1 mRNA CTD PMID:27157538 NCBI chr 1:114,385,484...114,422,741
Ensembl chr 1:114,386,757...114,422,733
JBrowse link
G Pdss1 decaprenyl diphosphate synthase subunit 1 decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of PDSS1 mRNA CTD PMID:21308897 NCBI chr17:90,033,432...90,072,506
Ensembl chr17:90,033,539...90,071,408
JBrowse link
G Pdss2 decaprenyl diphosphate synthase subunit 2 increases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in increased expression of PDSS2 mRNA CTD PMID:21308897 NCBI chr20:47,966,513...48,192,747
Ensembl chr20:47,966,583...48,192,743
JBrowse link
G Pink1 PTEN induced kinase 1 multiple interactions ISO PINK1 protein affects the reaction [Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone affects the localization of PRKN protein] CTD PMID:24879156 NCBI chr 5:156,677,146...156,689,258
Ensembl chr 5:156,677,146...156,689,415
JBrowse link
G Plcg1 phospholipase C, gamma 1 increases phosphorylation ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in increased phosphorylation of PLCG1 protein CTD PMID:19901985 NCBI chr 3:156,727,642...156,758,307
Ensembl chr 3:156,727,642...156,758,307
JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A multiple interactions ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone promotes the reaction [TARDBP protein binds to PPP1R15A protein] CTD PMID:29109149 NCBI chr 1:101,511,899...101,515,043
Ensembl chr 1:101,511,901...101,514,974
JBrowse link
G Prkaa1 protein kinase AMP-activated catalytic subunit alpha 1 increases phosphorylation ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in increased phosphorylation of PRKAA1 protein CTD PMID:19901985 NCBI chr 2:54,857,688...54,893,404
Ensembl chr 2:54,857,688...54,893,404
JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase multiple interactions
affects localization
ISO PINK1 protein affects the reaction [Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone affects the localization of PRKN protein] CTD PMID:24879156 NCBI chr 1:48,880,015...50,069,998 JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in increased expression of PTGS2 mRNA CTD PMID:16039398 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Rad23a RAD23 homolog A, nucleotide excision repair protein decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of RAD23A mRNA CTD PMID:16039398 NCBI chr19:25,949,488...25,956,677
Ensembl chr19:25,949,490...25,955,391
JBrowse link
G Rpl13a ribosomal protein L13A decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of RPL13A mRNA CTD PMID:16039398 NCBI chr 1:101,120,325...101,123,401
Ensembl chr 1:101,120,325...101,123,402
JBrowse link
G Serpine1 serpin family E member 1 decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of SERPINE1 mRNA CTD PMID:16039398 NCBI chr12:22,641,104...22,651,482
Ensembl chr12:22,641,104...22,651,482
JBrowse link
G Slc18a2 solute carrier family 18 member A2 multiple interactions EXP Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone inhibits the reaction [SLC18A2 protein results in increased uptake of Serotonin] CTD PMID:1438304 NCBI chr 1:280,397,831...280,457,968
Ensembl chr 1:280,423,079...280,457,148
JBrowse link
G Slc41a2 solute carrier family 41 member 2 increases expression EXP Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in increased expression of SLC41A2 mRNA CTD PMID:27157538 NCBI chr 7:26,522,314...26,607,861
Ensembl chr 7:26,522,314...26,607,861
JBrowse link
G Sod2 superoxide dismutase 2 increases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in increased expression of SOD2 mRNA CTD PMID:16039398 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
JBrowse link
G Stat3 signal transducer and activator of transcription 3 affects response to substance ISO STAT3 protein affects the susceptibility to Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone CTD PMID:20224768 NCBI chr10:88,790,401...88,842,263
Ensembl chr10:88,790,408...88,842,233
JBrowse link
G Tardbp TAR DNA binding protein multiple interactions ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone promotes the reaction [TARDBP protein binds to PPP1R15A protein] CTD PMID:29109149 NCBI chr 5:165,432,089...165,442,232
Ensembl chr 5:165,432,095...165,442,048
JBrowse link
G Xrcc5 X-ray repair cross complementing 5 decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of XRCC5 mRNA CTD PMID:16039398 NCBI chr 9:79,659,275...79,748,050
Ensembl chr 9:79,659,251...79,748,078
JBrowse link
chlortetracycline term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cat catalase decreases activity ISO Chlortetracycline results in decreased activity of CAT protein CTD PMID:30768968 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Gstp1 glutathione S-transferase pi 1 multiple interactions ISO Chlortetracycline inhibits the reaction [GSTP1 protein results in increased metabolism of 1-chloro-2,4-dinitrobenzene-glutathione conjugate] CTD PMID:23769903 NCBI chr 1:219,291,679...219,294,147
Ensembl chr 1:219,291,679...219,294,147
JBrowse link
desferrioxamine B term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aco1 aconitase 1 increases activity
increases expression
multiple interactions
EXP
ISO
Deferoxamine results in increased activity of ACO1 protein
Deferoxamine results in increased expression of ACO1 protein
[Deferoxamine results in decreased abundance of Iron] which results in increased activity of ACO1 protein
CTD PMID:10397746, PMID:11054110, PMID:15893546, PMID:16568477, PMID:18073202, PMID:25106854 NCBI chr 5:56,425,076...56,481,218
Ensembl chr 5:56,425,024...56,481,218
JBrowse link
G Aco2 aconitase 2 decreases expression EXP Deferoxamine results in decreased expression of ACO2 protein CTD PMID:16568477, PMID:17469137 NCBI chr 7:123,102,493...123,145,608
Ensembl chr 7:123,102,468...123,145,635
JBrowse link
G Acp5 acid phosphatase 5, tartrate resistant decreases activity
multiple interactions
ISO Deferoxamine results in decreased activity of ACP5 protein
Deferoxamine inhibits the reaction [TF protein results in increased activity of ACP5 protein]; TF protein inhibits the reaction [Deferoxamine results in decreased activity of ACP5 protein]
CTD PMID:31238089 NCBI chr 8:23,142,733...23,149,067
Ensembl chr 8:23,142,734...23,148,396
JBrowse link
G Acta2 actin alpha 2, smooth muscle decreases expression
increases expression
multiple interactions
EXP
ISO
Deferoxamine results in decreased expression of ACTA2 protein
Deferoxamine results in increased expression of ACTA2 mRNA
Deferoxamine inhibits the reaction [Artesunate results in decreased expression of ACTA2 mRNA]
CTD PMID:18032466, PMID:30551460 NCBI chr 1:252,537,614...252,550,394
Ensembl chr 1:252,537,615...252,550,394
JBrowse link
G Adm adrenomedullin increases expression ISO Deferoxamine results in increased expression of ADM mRNA CTD PMID:11754965 NCBI chr 1:175,443,189...175,447,260
Ensembl chr 1:175,445,088...175,447,259
JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions EXP Deferoxamine inhibits the reaction [PDGFB protein results in increased phosphorylation of AKT1 protein] CTD PMID:18032466 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Aldh3a1 aldehyde dehydrogenase 3 family, member A1 decreases expression
multiple interactions
ISO Deferoxamine results in decreased expression of ALDH3A1 mRNA
Deferoxamine inhibits the reaction [Benzo(a)pyrene results in increased expression of ALDH3A1 mRNA]
CTD PMID:14645679 NCBI chr10:47,490,168...47,499,855
Ensembl chr10:47,490,153...47,499,876
JBrowse link
G Alpl alkaline phosphatase, biomineralization associated decreases expression
multiple interactions
ISO Deferoxamine results in decreased expression of ALPL mRNA
Indomethacin promotes the reaction [Deferoxamine results in decreased expression of ALPL protein]; Sulindac promotes the reaction [Deferoxamine results in decreased expression of ALPL protein]
CTD PMID:16772336, PMID:21882223 NCBI chr 5:156,086,496...156,141,513
Ensembl chr 5:156,086,497...156,141,537
JBrowse link
G Anxa3 annexin A3 multiple interactions
decreases expression
ISO ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of ANXA3 protein]
Deferoxamine results in decreased expression of ANXA3 protein
CTD PMID:19515424 NCBI chr14:14,371,921...14,426,503
Ensembl chr14:14,364,008...14,426,437
JBrowse link
G App amyloid beta precursor protein affects binding
multiple interactions
ISO Deferoxamine binds to APP 5' UTR
[Deferoxamine binds to APP 5' UTR] which results in decreased expression of APP protein; [Deferoxamine binds to APP 5' UTR] which results in decreased secretion of APP protein modified form; Deferoxamine inhibits the reaction [[[[APP protein modified form binds to Copper] which co-treated with Ascorbic Acid] results in increased oxidation of phosphatidylcholine hydroperoxide] which results in increased chemical synthesis of 4-hydroxy-2-nonenal]
CTD PMID:15681799, PMID:17964426 NCBI chr11:24,425,013...24,641,872
Ensembl chr11:24,425,005...24,641,858
JBrowse link
G Aqp4 aquaporin 4 multiple interactions EXP Deferoxamine inhibits the reaction [manganese(III) acetate dihydrate results in increased expression of AQP4 protein] CTD PMID:20648640 NCBI chr18:6,766,009...6,782,757
Ensembl chr18:6,765,945...6,782,996
JBrowse link
G Arhgdia Rho GDP dissociation inhibitor alpha decreases expression
multiple interactions
ISO Deferoxamine results in decreased expression of ARHGDIA protein
ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of ARHGDIA protein]
CTD PMID:19515424 NCBI chr10:109,754,012...109,757,506
Ensembl chr10:109,754,004...109,757,550
JBrowse link
G Arnt aryl hydrocarbon receptor nuclear translocator increases activity EXP Deferoxamine results in increased activity of ARNT protein CTD PMID:10559391 NCBI chr 2:196,594,178...196,651,486
Ensembl chr 2:196,594,303...196,651,179
JBrowse link
G Ash2l ASH2 like histone lysine methyltransferase complex subunit increases expression
affects expression
ISO Deferoxamine results in increased expression of ASH2L mRNA
Deferoxamine affects the expression of ASH2L mRNA
CTD PMID:23483119 NCBI chr16:71,011,315...71,033,171
Ensembl chr16:71,011,332...71,032,790
JBrowse link
G Atf1 activating transcription factor 1 increases activity EXP Deferoxamine results in increased activity of ATF1 protein CTD PMID:10559391 NCBI chr 7:141,882,261...141,924,790
Ensembl chr 7:141,882,251...141,924,788
JBrowse link
G Atm ATM serine/threonine kinase multiple interactions ISO Deferoxamine results in increased phosphorylation of and results in increased activity of ATM protein CTD PMID:16959548 NCBI chr 8:58,015,938...58,119,973
Ensembl chr 8:58,015,940...58,120,045
JBrowse link
G Atp6v0d2 ATPase H+ transporting V0 subunit D2 multiple interactions
affects expression
ISO Deferoxamine affects the reaction [TF protein affects the expression of ATP6V0D2 mRNA]; TF protein affects the reaction [Deferoxamine affects the expression of ATP6V0D2 mRNA] CTD PMID:31238089 NCBI chr 5:33,843,591...33,892,446
Ensembl chr 5:33,843,519...33,892,462
JBrowse link
G Atp7a ATPase copper transporting alpha increases expression
multiple interactions
EXP Deferoxamine results in increased expression of ATP7A mRNA
cupric chloride promotes the reaction [Deferoxamine results in increased expression of ATP7A mRNA]; Deferoxamine promotes the reaction [cupric chloride results in increased expression of ATP7A protein]
CTD PMID:23174565 NCBI chr  X:77,076,085...77,193,644
Ensembl chr  X:77,076,106...77,193,644
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression
multiple interactions
ISO Deferoxamine results in increased expression of BAX mRNA
Deferoxamine inhibits the reaction [Hydrogen Peroxide affects the localization of BAX protein]
CTD PMID:16800926, PMID:21742779 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions EXP Deferoxamine inhibits the reaction [Copper Sulfate results in decreased expression of BCL2 mRNA] CTD PMID:30431687 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Becn1 beclin 1 multiple interactions ISO Deferoxamine inhibits the reaction [di-n-propyldithiocarbamate results in increased expression of BECN1 protein]; Deferoxamine inhibits the reaction [Hydrogen Peroxide affects the localization of BECN1 protein] CTD PMID:21742779, PMID:32687844 NCBI chr10:89,209,944...89,225,297
Ensembl chr10:89,209,940...89,225,297
JBrowse link
G Bmp6 bone morphogenetic protein 6 multiple interactions ISO Deferoxamine inhibits the reaction [BMP6 protein results in increased expression of HAMP mRNA]; ferric ammonium citrate affects the reaction [Deferoxamine inhibits the reaction [BMP6 protein results in increased expression of HAMP mRNA]] CTD PMID:25633564 NCBI chr17:26,955,142...27,112,820
Ensembl chr17:26,955,142...27,112,820
JBrowse link
G Bnip3l BCL2 interacting protein 3 like increases expression ISO Deferoxamine results in increased expression of BNIP3L mRNA CTD PMID:11832486 NCBI chr15:43,643,897...43,667,123
Ensembl chr15:43,643,897...43,667,029
JBrowse link
G C5 complement C5 multiple interactions ISO Deferoxamine inhibits the reaction [Asbestos, Crocidolite results in increased cleavage of C5 protein]; Deferoxamine inhibits the reaction [Asbestos, Serpentine results in increased cleavage of C5 protein] CTD PMID:10777245 NCBI chr 3:14,049,993...14,113,931
NCBI chr 3:14,206,466...14,229,141
Ensembl chr 3:14,049,995...14,229,080
JBrowse link
G Ca9 carbonic anhydrase 9 increases expression ISO Deferoxamine results in increased expression of CA9 mRNA CTD PMID:25351418 NCBI chr 5:59,008,277...59,015,535
Ensembl chr 5:59,008,933...59,015,528
JBrowse link
G Cacna1h calcium voltage-gated channel subunit alpha1 H increases expression EXP Deferoxamine results in increased expression of CACNA1H mRNA CTD PMID:12679337 NCBI chr10:14,730,932...14,789,201
Ensembl chr10:14,730,941...14,788,617
JBrowse link
G Car2 carbonic anhydrase 2 decreases expression ISO Deferoxamine results in decreased expression of CAR2 mRNA CTD PMID:31238089 NCBI chr 2:88,097,740...88,112,868
Ensembl chr 2:88,097,720...88,113,029
JBrowse link
G Casp12 caspase 12 multiple interactions ISO Deferoxamine promotes the reaction [manganese chloride results in increased cleavage of and results in increased activity of CASP12 protein] CTD PMID:23764342 NCBI chr 8:2,658,892...2,686,160
Ensembl chr 8:2,659,865...2,686,160
JBrowse link
G Casp3 caspase 3 increases expression
multiple interactions
increases activity
ISO
EXP
Deferoxamine results in increased expression of CASP3 protein
Deferoxamine inhibits the reaction [ferric ammonium citrate results in increased cleavage of CASP3 protein]
Deferoxamine results in increased activity of CASP3 protein
Deferoxamine promotes the reaction [manganese chloride results in increased activity of CASP3 protein]; Nitroprusside inhibits the reaction [Deferoxamine results in increased activity of CASP3 protein]; Vanadates inhibits the reaction [Deferoxamine results in increased activity of CASP3 protein]
Deferoxamine inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased activity of CASP3 protein]; Deferoxamine inhibits the reaction [Copper Sulfate results in increased secretion of CASP3 protein]; Deferoxamine inhibits the reaction [Manganese results in increased activity of CASP3 protein]
CTD PMID:11933051, PMID:12523938, PMID:16374551, PMID:16800926, PMID:23764342, PMID:26318285, PMID:30431687 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp8 caspase 8 increases activity
multiple interactions
ISO Deferoxamine results in increased activity of CASP8 protein
Nitroprusside inhibits the reaction [Deferoxamine results in increased activity of CASP8 protein]; Vanadates inhibits the reaction [Deferoxamine results in increased activity of CASP8 protein]
CTD PMID:16374551 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Casp9 caspase 9 multiple interactions ISO Deferoxamine inhibits the reaction [Asbestos, Amosite results in increased activity of CASP9 protein] CTD PMID:12540492, PMID:14766669 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Cat catalase multiple interactions EXP Deferoxamine inhibits the reaction [Potassium Dichromate results in decreased activity of CAT protein] CTD PMID:22115772 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Cav1 caveolin 1 increases expression ISO Deferoxamine results in increased expression of CAV1 protein CTD PMID:16927372 NCBI chr 4:44,597,123...44,630,206
Ensembl chr 4:44,597,123...44,630,200
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions EXP Deferoxamine inhibits the reaction [[Lipopolysaccharides co-treated with Fructose co-treated with Copper deficiency] results in increased expression of CCL2 protein] CTD PMID:25813056 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ccna2 cyclin A2 decreases expression ISO Deferoxamine results in decreased expression of CCNA2 protein CTD PMID:11468187 NCBI chr 2:123,274,727...123,282,266
Ensembl chr 2:123,275,881...123,282,214
JBrowse link
G Ccnb1 cyclin B1 decreases expression ISO Deferoxamine results in decreased expression of CCNB1 protein CTD PMID:11468187 NCBI chr 2:30,782,133...30,791,106
Ensembl chr 2:30,783,915...30,791,221
JBrowse link
G Ccnd1 cyclin D1 decreases expression ISO Deferoxamine results in decreased expression of CCND1 protein CTD PMID:11468187 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Ccnd2 cyclin D2 decreases expression ISO Deferoxamine results in decreased expression of CCND2 protein CTD PMID:11468187 NCBI chr 4:159,674,885...159,697,207
Ensembl chr 4:159,674,885...159,697,207
JBrowse link
G Ccnd3 cyclin D3 decreases expression ISO Deferoxamine results in decreased expression of CCND3 protein CTD PMID:11468187 NCBI chr 9:15,404,816...15,410,905
Ensembl chr 9:15,404,822...15,410,943
JBrowse link
G Ccne1 cyclin E1 increases expression ISO Deferoxamine results in increased expression of CCNE1 protein CTD PMID:11468187 NCBI chr 1:94,485,830...94,495,112
Ensembl chr 1:94,485,832...94,494,980
JBrowse link
G Cd36 CD36 molecule decreases expression ISO Deferoxamine results in decreased expression of CD36 protein CTD PMID:24170104 NCBI chr 4:14,150,309...14,191,498
Ensembl chr 4:14,001,761...14,249,749
JBrowse link
G Cdc14a cell division cycle 14A increases expression ISO Deferoxamine results in increased expression of CDC14A mRNA alternative form CTD PMID:16760464 NCBI chr 2:219,302,577...219,458,345
Ensembl chr 2:219,302,577...219,458,271
JBrowse link
G Cdk2 cyclin dependent kinase 2 decreases activity
decreases expression
ISO Deferoxamine results in decreased activity of CDK2 protein
Deferoxamine results in decreased expression of CDK2 protein
CTD PMID:11468187, PMID:17631934 NCBI chr 7:3,124,953...3,132,533
Ensembl chr 7:3,124,954...3,132,457
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression
decreases expression
ISO
EXP
Deferoxamine results in increased expression of CDKN1A mRNA; Deferoxamine results in increased expression of CDKN1A protein
Deferoxamine results in decreased expression of CDKN1A protein
CTD PMID:10397746, PMID:10559391, PMID:11468187, PMID:12807743, PMID:16227210, PMID:23483119 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Ckb creatine kinase B multiple interactions EXP [Deferoxamine co-treated with Acetylcysteine] inhibits the reaction [Acetaminophen results in decreased activity of CKB protein]; [Deferoxamine co-treated with Acetylcysteine] inhibits the reaction [Carbon Tetrachloride results in decreased activity of CKB protein] CTD PMID:19688255 NCBI chr 6:136,142,956...136,145,838
Ensembl chr 6:136,142,956...136,145,837
JBrowse link
G Col1a1 collagen type I alpha 1 chain multiple interactions EXP Deferoxamine inhibits the reaction [Asbestos, Amosite results in increased expression of COL1A1 mRNA] CTD PMID:11306436 NCBI chr10:82,745,801...82,762,790
Ensembl chr10:82,745,801...82,762,789
JBrowse link
G Cox4i1 cytochrome c oxidase subunit 4i1 multiple interactions ISO Deferoxamine inhibits the reaction [EPAS1 protein results in increased degradation of COX4I1 protein] CTD PMID:18515279 NCBI chr19:54,245,958...54,252,198
Ensembl chr19:54,245,950...54,252,225
JBrowse link
G Cp ceruloplasmin multiple interactions ISO Deferoxamine inhibits the reaction [CP protein results in increased oxidation of 3-carboxy-2,2,5,5-tetramethylpyrrolidin-1-yloxyl] CTD PMID:22824865 NCBI chr 2:104,744,249...104,803,034
Ensembl chr 2:104,744,461...104,799,853
JBrowse link
G Creb1 cAMP responsive element binding protein 1 increases activity EXP Deferoxamine results in increased activity of CREB1 protein CTD PMID:10559391 NCBI chr 9:71,229,753...71,298,994
Ensembl chr 9:71,230,108...71,293,435
JBrowse link
G Crp C-reactive protein multiple interactions EXP Deferoxamine inhibits the reaction [Copper Sulfate results in increased secretion of CRP protein] CTD PMID:30431687 NCBI chr13:91,080,448...91,081,358
Ensembl chr13:91,054,974...91,093,713
JBrowse link
G Csf2 colony stimulating factor 2 multiple interactions ISO Deferoxamine inhibits the reaction [Particulate Matter results in increased expression of CSF2 mRNA] CTD PMID:20801209, PMID:21703343 NCBI chr10:39,602,089...39,604,070
Ensembl chr10:39,602,089...39,604,070
JBrowse link
G Ctnnb1 catenin beta 1 multiple interactions ISO Deferoxamine inhibits the reaction [ferumoxides results in increased activity of CTNNB1 protein] CTD PMID:20338187 NCBI chr 8:129,601,511...129,628,378
Ensembl chr 8:129,617,812...129,627,372
JBrowse link
G Ctsk cathepsin K multiple interactions
decreases expression
ISO Deferoxamine inhibits the reaction [TF protein results in increased expression of CTSK mRNA]; TF protein affects the reaction [Deferoxamine results in decreased expression of CTSK mRNA] CTD PMID:31238089 NCBI chr 2:196,655,469...196,666,447
Ensembl chr 2:196,655,469...196,666,446
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 multiple interactions EXP Deferoxamine promotes the reaction [Asbestos, Amphibole results in increased expression of CXCL2] CTD PMID:21605006 NCBI chr14:18,731,346...18,733,391
Ensembl chr14:18,731,378...18,733,391
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions ISO Deferoxamine inhibits the reaction [Particulate Matter results in increased expression of CYP1A1 mRNA]
Deferoxamine inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]; ferrous sulfate inhibits the reaction [Deferoxamine inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]]
CTD PMID:10799651, PMID:10823667, PMID:20801209, PMID:21703343 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions EXP Deferoxamine inhibits the reaction [CYP2E1 protein results in increased reduction of tirapazamine] CTD PMID:7710944 NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 multiple interactions ISO Deferoxamine promotes the reaction [manganese chloride results in increased expression of DDIT3 protein] CTD PMID:23764342 NCBI chr 7:70,578,564...70,585,074
Ensembl chr 7:70,580,198...70,585,084
JBrowse link
G Des desmin multiple interactions
increases expression
ISO Deferoxamine inhibits the reaction [Artesunate results in decreased expression of DES mRNA]
Deferoxamine results in increased expression of DES mRNA
CTD PMID:30551460 NCBI chr 9:82,556,574...82,564,288
Ensembl chr 9:82,556,573...82,564,294
JBrowse link
G Dicer1 dicer 1 ribonuclease III decreases expression ISO Deferoxamine results in decreased expression of DICER1 mRNA; Deferoxamine results in decreased expression of DICER1 protein CTD PMID:25351418 NCBI chr 6:128,388,084...128,453,234
Ensembl chr 6:128,388,053...128,434,183
JBrowse link
G Dio2 iodothyronine deiodinase 2 increases activity EXP Deferoxamine results in increased activity of DIO2 protein CTD PMID:17615150 NCBI chr 6:114,475,156...114,489,443
Ensembl chr 6:114,476,142...114,476,723
JBrowse link
G Dnm1l dynamin 1-like multiple interactions ISO Deferoxamine inhibits the reaction [ferric ammonium citrate results in decreased phosphorylation of DNM1L protein] CTD PMID:26318285 NCBI chr11:88,830,968...88,882,271
Ensembl chr11:88,830,957...88,880,198
JBrowse link
G Dnmt1 DNA methyltransferase 1 increases expression
decreases expression
ISO Deferoxamine results in increased expression of DNMT1 mRNA
Deferoxamine results in decreased expression of DNMT1 mRNA
CTD PMID:23483119 NCBI chr 8:21,922,515...21,968,495
Ensembl chr 8:21,922,515...21,968,495
JBrowse link
G Dnmt3a DNA methyltransferase 3 alpha decreases expression
increases expression
ISO Deferoxamine results in decreased expression of DNMT3A mRNA
Deferoxamine results in increased expression of DNMT3A mRNA
CTD PMID:23483119 NCBI chr 6:28,205,375...28,346,052
Ensembl chr 6:28,235,695...28,340,577
JBrowse link
G Dnmt3b DNA methyltransferase 3 beta decreases expression
increases expression
ISO Deferoxamine results in decreased expression of DNMT3B mRNA
Deferoxamine results in increased expression of DNMT3B mRNA
CTD PMID:23483119 NCBI chr 3:149,131,541...149,170,061
Ensembl chr 3:149,131,785...149,208,786
JBrowse link
G Duox1 dual oxidase 1 multiple interactions ISO Deferoxamine inhibits the reaction [Particulate Matter results in increased expression of DUOX1 mRNA] CTD PMID:21703343 NCBI chr 3:114,251,794...114,286,827
Ensembl chr 3:114,253,637...114,286,802
JBrowse link
G Duox2 dual oxidase 2 multiple interactions ISO Deferoxamine inhibits the reaction [Particulate Matter results in increased expression of DUOX2 mRNA] CTD PMID:21703343 NCBI chr 3:114,218,187...114,237,808
Ensembl chr 3:114,218,193...114,235,933
JBrowse link
G Dusp1 dual specificity phosphatase 1 increases expression EXP Deferoxamine results in increased expression of DUSP1 mRNA CTD PMID:11577072 NCBI chr10:16,970,642...16,973,425
Ensembl chr10:16,970,626...16,973,418
JBrowse link
G Edn1 endothelin 1 increases expression EXP Deferoxamine results in increased expression of EDN1 protein CTD PMID:9357851 NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324
JBrowse link
G Egfr epidermal growth factor receptor multiple interactions ISO Deferoxamine inhibits the reaction [Asbestos, Crocidolite results in decreased activity of and results in decreased phosphorylation of EGFR protein] CTD PMID:15626777 NCBI chr14:99,919,485...100,104,136
Ensembl chr14:99,919,485...100,098,796
JBrowse link
G Egln1 egl-9 family hypoxia-inducible factor 1 decreases expression ISO Deferoxamine results in decreased expression of EGLN1 protein CTD PMID:22245592 NCBI chr19:57,660,194...57,701,158
Ensembl chr19:57,662,278...57,699,113
JBrowse link
G Ehmt2 euchromatic histone lysine methyltransferase 2 decreases expression ISO Deferoxamine results in decreased expression of EHMT2 mRNA CTD PMID:23483119 NCBI chr20:4,576,033...4,592,980
Ensembl chr20:4,576,057...4,592,980
JBrowse link
G Elane elastase, neutrophil expressed multiple interactions ISO Deferoxamine inhibits the reaction [ELANE protein results in increased expression of MUC5AC mRNA] CTD PMID:11919081 NCBI chr 7:12,638,320...12,640,168
Ensembl chr 7:12,638,322...12,640,232
JBrowse link
G Eno1 enolase 1 increases expression ISO Deferoxamine results in increased expression of ENO1 mRNA CTD PMID:16227210 NCBI chr 5:167,288,223...167,299,610
Ensembl chr 5:167,288,223...167,299,609
JBrowse link
G Epas1 endothelial PAS domain protein 1 multiple interactions
increases expression
increases stability
ISO
EXP
Deferoxamine inhibits the reaction [EPAS1 protein results in increased degradation of COX4I1 protein]
Deferoxamine results in increased expression of EPAS1 protein
Deferoxamine results in increased stability of EPAS1 protein
CTD PMID:18353899, PMID:18515279, PMID:21558026, PMID:27287256 NCBI chr 6:10,306,508...10,385,239
Ensembl chr 6:10,306,405...10,387,265
JBrowse link
G Epo erythropoietin increases expression
increases stability
multiple interactions
ISO
EXP
Deferoxamine results in increased expression of EPO mRNA
Deferoxamine deficiency results in increased expression of EPO mRNA; Deferoxamine results in increased expression of EPO mRNA
Deferoxamine deficiency results in increased stability of EPO mRNA
Deferoxamine results in increased expression of EPO mRNA; Deferoxamine results in increased expression of EPO protein
Deferoxamine inhibits the reaction [Reactive Oxygen Species results in decreased expression of EPO protein]
CTD PMID:9927288, PMID:10559391, PMID:10699462, PMID:10756076, PMID:21558026 NCBI chr12:22,274,828...22,278,268
Ensembl chr12:22,274,828...22,278,266
JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 multiple interactions ISO Deferoxamine promotes the reaction [Palmitic Acid results in increased phosphorylation of ERN1 protein] CTD PMID:32283200 NCBI chr10:94,588,555...94,682,072
Ensembl chr10:94,588,555...94,681,914
JBrowse link
G Ero1a endoplasmic reticulum oxidoreductase 1 alpha increases expression ISO
EXP
Deferoxamine results in increased expression of ERO1A mRNA CTD PMID:12752442 NCBI chr15:19,619,947...19,655,381
Ensembl chr15:19,619,973...19,655,381
JBrowse link
G Erp29 endoplasmic reticulum protein 29 decreases expression
multiple interactions
ISO Deferoxamine results in decreased expression of ERP29 protein
ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of ERP29 protein]
CTD PMID:19515424 NCBI chr12:40,619,377...40,625,884
Ensembl chr12:40,619,377...40,625,883
JBrowse link
G F3 coagulation factor III, tissue factor multiple interactions ISO Deferoxamine inhibits the reaction [ferric ammonium citrate results in increased expression of F3 mRNA] CTD PMID:25858758 NCBI chr 2:225,310,686...225,322,281
Ensembl chr 2:225,310,624...225,322,272
JBrowse link
G Fabp4 fatty acid binding protein 4 decreases expression ISO Deferoxamine results in decreased expression of FABP4 mRNA CTD PMID:12032628 NCBI chr 2:93,792,666...93,797,267
Ensembl chr 2:93,792,601...93,797,305
JBrowse link
G Fech ferrochelatase decreases expression
multiple interactions
ISO Deferoxamine results in decreased expression of FECH protein
ferric chloride inhibits the reaction [Deferoxamine results in decreased expression of FECH protein]
CTD PMID:30517741 NCBI chr18:59,941,992...59,975,192
Ensembl chr18:59,941,992...59,975,192
JBrowse link
G Fn1 fibronectin 1 multiple interactions ISO Deferoxamine inhibits the reaction [Artesunate results in decreased expression of FN1 mRNA] CTD PMID:30551460 NCBI chr 9:78,900,111...78,969,018
Ensembl chr 9:78,900,103...78,969,078
JBrowse link
G Fth1 ferritin heavy chain 1 decreases expression
multiple interactions
ISO
EXP
Deferoxamine results in decreased expression of FTH1 protein
Deferoxamine inhibits the reaction [di-n-propyldithiocarbamate results in decreased expression of FTH1 protein]
[Deferoxamine results in decreased abundance of Iron] which results in decreased expression of FTH1 mRNA
CTD PMID:15893546, PMID:16568477, PMID:16777245, PMID:17469137, PMID:32687844 NCBI chr 1:226,030,940...226,033,228
Ensembl chr 1:226,030,938...226,033,228
JBrowse link
G Ftl1 ferritin light chain 1 multiple interactions
decreases expression
ISO
EXP
[Deferoxamine results in decreased abundance of Iron] which results in decreased expression of FTL mRNA; Deferoxamine inhibits the reaction [Doxorubicin promotes the reaction [Iron binds to [FTL protein binds to FTMT protein]]]; Deferoxamine inhibits the reaction [Iron binds to [FTL protein binds to FTMT protein]]
Deferoxamine results in decreased expression of FTL1 protein
CTD PMID:12393473, PMID:12644586, PMID:15893546, PMID:16568477 NCBI chr 1:101,448,190...101,450,034
Ensembl chr 1:101,448,346...101,449,829
JBrowse link
G Ftmt ferritin mitochondrial multiple interactions ISO Deferoxamine inhibits the reaction [Doxorubicin promotes the reaction [Iron binds to [FTL protein binds to FTMT protein]]]; Deferoxamine inhibits the reaction [Iron binds to [FTL protein binds to FTMT protein]] CTD PMID:12644586 NCBI chr18:47,294,292...47,295,541
Ensembl chr18:47,294,292...47,295,541
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha increases expression ISO Deferoxamine results in increased expression of GADD45A mRNA CTD PMID:10397746, PMID:11468187 NCBI chr 4:97,782,512...97,784,814
Ensembl chr 4:97,782,512...97,784,842
JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase decreases expression
multiple interactions
ISO Deferoxamine results in decreased expression of GAPDH protein
ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of GAPDH protein]
CTD PMID:19515424 NCBI chr 4:157,676,336...157,680,322
Ensembl chr 4:157,676,595...157,679,962
JBrowse link
G Gas1 growth arrest-specific 1 multiple interactions ISO [Deferoxamine results in decreased abundance of Iron] which results in decreased expression of GAS1 mRNA CTD PMID:12393473 NCBI chr17:4,846,116...4,849,350
Ensembl chr17:4,846,789...4,847,940
JBrowse link
G Gbe1 1,4-alpha-glucan branching enzyme 1 increases expression ISO Deferoxamine results in increased expression of GBE1 mRNA CTD PMID:15094311 NCBI chr11:7,210,169...7,485,895
Ensembl chr11:7,210,209...7,485,890
JBrowse link
G Gck glucokinase affects expression EXP Deferoxamine affects the expression of GCK mRNA CTD PMID:9761743 NCBI chr14:86,149,146...86,191,589
Ensembl chr14:86,148,928...86,190,659
JBrowse link
G Glo1 glyoxalase 1 increases expression
multiple interactions
ISO Deferoxamine results in increased expression of GLO1 protein
ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of GLO1 protein]
CTD PMID:19515424 NCBI chr20:9,273,589...9,291,608
Ensembl chr20:9,273,594...9,291,610
JBrowse link
G Gosr1 golgi SNAP receptor complex member 1 multiple interactions ISO GOSR1 protein affects the reaction [Deferoxamine inhibits the reaction [Nitroprusside results in decreased phosphorylation of MAPK1 protein]]; GOSR1 protein affects the reaction [Deferoxamine inhibits the reaction [Nitroprusside results in decreased phosphorylation of MAPK3 protein]] CTD PMID:31066958 NCBI chr10:63,405,526...63,442,257
Ensembl chr10:63,405,586...63,442,250
JBrowse link
G Gpx4 glutathione peroxidase 4 multiple interactions ISO Deferoxamine inhibits the reaction [Busulfan results in decreased expression of GPX4 protein] CTD PMID:32416107 NCBI chr 7:12,516,357...12,519,154
Ensembl chr 7:12,516,352...12,519,154
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions
decreases phosphorylation
ISO Deferoxamine inhibits the reaction [Fenretinide results in increased phosphorylation of GSK3B protein]
Deferoxamine results in decreased phosphorylation of GSK3B protein
CTD PMID:25246272 NCBI chr11:65,060,884...65,208,842
Ensembl chr11:65,066,235...65,209,268
JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions EXP Deferoxamine inhibits the reaction [Potassium Dichromate results in decreased activity of GSR protein] CTD PMID:22115772 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
JBrowse link
G Hamp hepcidin antimicrobial peptide multiple interactions
decreases expression
affects expression
ISO
EXP
Deferoxamine inhibits the reaction [BMP6 protein results in increased expression of HAMP mRNA]; Deferoxamine promotes the reaction [ferric ammonium citrate results in decreased expression of HAMP mRNA]; ferric ammonium citrate affects the reaction [Deferoxamine inhibits the reaction [BMP6 protein results in increased expression of HAMP mRNA]]
Deferoxamine results in decreased expression of HAMP protein
Deferoxamine affects the expression of HAMP mRNA
CTD PMID:21558026, PMID:25633564 NCBI chr 1:89,368,021...89,369,960
Ensembl chr 1:89,368,021...89,369,960
JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 multiple interactions EXP Deferoxamine inhibits the reaction [Copper Sulfate results in increased expression of HAVCR1 protein] CTD PMID:30431687 NCBI chr10:31,813,819...31,860,934
Ensembl chr10:31,813,814...31,848,379
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha multiple interactions
increases expression
increases stability
increases activity
decreases degradation
affects localization
ISO
EXP
15,16-dihydrotanshinone I inhibits the reaction [Deferoxamine results in increased expression of HIF1A protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Deferoxamine results in increased expression of HIF1A protein]; 3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole inhibits the reaction [Deferoxamine results in increased expression of HIF1A protein]; [Deferoxamine results in decreased abundance of Iron] which results in increased expression of HIF1A mRNA; Arsenic Trioxide promotes the reaction [Deferoxamine results in increased expression of HIF1A protein]; Cadmium inhibits the reaction [Deferoxamine results in increased expression of HIF1A protein]; Deferoxamine promotes the reaction [[HIF1A protein binds to VEGFA promoter] which results in increased expression of VEGFA mRNA]; Deferoxamine results in increased expression of and results in increased stability of HIF1A protein; Deferoxamine results in increased stability of and results in increased expression of HIF1A protein; ferric citrate inhibits the reaction [Deferoxamine results in increased expression of HIF1A protein]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [Deferoxamine results in increased expression of HIF1A protein]; ST6GAL1 protein promotes the reaction [Deferoxamine results in increased expression of HIF1A protein]; TP53 gene mutant form promotes the reaction [Deferoxamine results in increased expression of HIF1A protein]
Deferoxamine results in increased stability of HIF1A protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Deferoxamine results in increased expression of HIF1A protein]; ferric citrate inhibits the reaction [Deferoxamine results in increased expression of HIF1A protein]
Deferoxamine results in increased activity of HIF1A protein
[Deferoxamine results in increased activity of HIF1A protein] which results in decreased susceptibility to Carmustine
Deferoxamine results in decreased degradation of HIF1A protein
Deferoxamine affects the localization of HIF1A protein
CTD PMID:10559391, PMID:10866824, PMID:11286986, PMID:12393473, PMID:14604972, PMID:14980978, PMID:15840558, PMID:15902299, PMID:16227210, PMID:16330433, PMID:16374551, PMID:16527254, PMID:16772336, PMID:16775626, PMID:17015263, PMID:17364964, PMID:18655187, PMID:19695866, PMID:20546814, PMID:21558026, PMID:22245592, PMID:23483119, PMID:24403227, PMID:26282490, PMID:27287256, PMID:29475939 NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052
JBrowse link
G Hif3a hypoxia inducible factor 3 subunit alpha increases expression ISO Deferoxamine results in increased expression of HIF3A protein CTD PMID:16775626 NCBI chr 1:78,976,318...78,997,869
Ensembl chr 1:78,976,318...78,997,869
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
decreases degradation
decreases expression
ISO
EXP
Deferoxamine inhibits the reaction [HMOX1 protein results in increased abundance of Superoxides]
Deferoxamine results in decreased degradation of HMOX1 protein
Deferoxamine results in decreased expression of HMOX1 mRNA
[Deferoxamine results in decreased abundance of Iron] which results in decreased expression of HMOX1 mRNA; Deferoxamine inhibits the reaction [Cadmium Chloride results in increased activity of HMOX1 protein]; Deferoxamine inhibits the reaction [Cadmium Chloride results in increased expression of HMOX1 mRNA]; Deferoxamine inhibits the reaction [Cadmium Chloride results in increased expression of HMOX1 protein]; Deferoxamine inhibits the reaction [Ethacrynic Acid affects the localization of HMOX1 protein]; Deferoxamine inhibits the reaction [Ethacrynic Acid results in increased expression of HMOX1 mRNA]; Deferoxamine inhibits the reaction [Fenretinide results in increased expression of HMOX1 protein]; Deferoxamine inhibits the reaction [Oxygen results in increased expression of HMOX1 mRNA]; Deferoxamine inhibits the reaction [phenethyl isothiocyanate results in increased expression of HMOX1 mRNA]; Deferoxamine inhibits the reaction [phenethyl isothiocyanate results in increased expression of HMOX1 protein]; Deferoxamine inhibits the reaction [sulforafan results in increased expression of HMOX1 mRNA]; Deferoxamine inhibits the reaction [Zinc results in increased expression of HMOX1 mRNA]; Deferoxamine inhibits the reaction [Zinc results in increased expression of HMOX1 protein]; ferrous sulfate inhibits the reaction [Deferoxamine inhibits the reaction [Cadmium Chloride results in increased activity of HMOX1 protein]]; ferrous sulfate inhibits the reaction [Deferoxamine inhibits the reaction [Cadmium Chloride results in increased expression of HMOX1 mRNA]]; ferrous sulfate inhibits the reaction [Deferoxamine inhibits the reaction [phenethyl isothiocyanate results in increased expression of HMOX1 mRNA]]; ferrous sulfate inhibits the reaction [Deferoxamine inhibits the reaction [phenethyl isothiocyanate results in increased expression of HMOX1 protein]]; ferrous sulfate inhibits the reaction [Deferoxamine inhibits the reaction [sulforafan results in increased expression of HMOX1 mRNA]]
Deferoxamine inhibits the reaction [HMOX1 protein results in increased abundance of Superoxides]; Deferoxamine inhibits the reaction [Nitroprusside results in increased expression of HMOX1 protein]
CTD PMID:9747510, PMID:10814519, PMID:12393473, PMID:16439612, PMID:18073186, PMID:19384570, PMID:20934533, PMID:22564156, PMID:25246272, PMID:26945724 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A multiple interactions
decreases expression
ISO ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of HSPA1A protein]
Deferoxamine results in decreased expression of HSPA1A protein
CTD PMID:19515424 NCBI chr20:4,875,834...4,881,751
Ensembl chr20:4,877,324...4,879,779
JBrowse link
G Hspa1l heat shock protein family A (Hsp70) member 1 like multiple interactions ISO [Deferoxamine results in decreased abundance of Iron] which results in decreased expression of HSPA1L mRNA CTD PMID:12393473 NCBI chr20:4,879,998...4,965,191
Ensembl chr20:4,959,294...4,964,963
JBrowse link
G Hspa9 heat shock protein family A (Hsp70) member 9 multiple interactions ISO [Deferoxamine results in decreased abundance of Iron] which results in decreased expression of HSPA9 mRNA CTD PMID:12393473 NCBI chr18:27,731,072...27,749,235
Ensembl chr18:27,731,072...27,749,235
JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 multiple interactions
decreases expression
ISO ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of HSPD1 protein]
Deferoxamine results in decreased expression of HSPD1 protein
CTD PMID:19515424, PMID:24170104 NCBI chr 9:61,680,529...61,691,202
Ensembl chr 9:61,680,530...61,690,956
JBrowse link
G Hsph1 heat shock protein family H (Hsp110) member 1 multiple interactions ISO [Deferoxamine results in decreased abundance of Iron] which results in decreased expression of HSPH1 mRNA CTD PMID:12393473 NCBI chr12:6,322,685...6,341,898
Ensembl chr12:6,322,668...6,341,902
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO [Deferoxamine affects the abundance of Iron] inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]; [Deferoxamine affects the abundance of Iron] inhibits the reaction [TNF protein results in increased expression of ICAM1 protein] CTD PMID:12633744 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
JBrowse link
G Il10 interleukin 10 multiple interactions EXP Deferoxamine inhibits the reaction [Copper Sulfate results in decreased secretion of IL10 protein] CTD PMID:30431687 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G Il1a interleukin 1 alpha multiple interactions ISO Deferoxamine inhibits the reaction [Particulate Matter results in increased expression of IL1A mRNA] CTD PMID:21703343 NCBI chr 3:121,824,712...121,836,122
Ensembl chr 3:121,825,412...121,836,086
JBrowse link
G Il1b interleukin 1 beta multiple interactions
decreases expression
ISO Deferoxamine inhibits the reaction [Particulate Matter results in increased expression of IL1B mRNA]; Deferoxamine promotes the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]; ferric chloride inhibits the reaction [Deferoxamine promotes the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]]
Deferoxamine inhibits the reaction [Asbestos, Crocidolite results in increased secretion of IL1B protein]
Deferoxamine results in decreased expression of IL1B mRNA
CTD PMID:9851740, PMID:18403674, PMID:20801209 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il4 interleukin 4 multiple interactions EXP Deferoxamine inhibits the reaction [Mercuric Chloride results in increased expression of IL4 mRNA] CTD PMID:11222498 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531
JBrowse link
G Il6 interleukin 6 multiple interactions ISO
EXP
Deferoxamine inhibits the reaction [2,2',4,4'-tetrabromodiphenyl ether results in increased expression of and results in increased secretion of IL6 protein]; Deferoxamine inhibits the reaction [Coal Ash results in increased expression of IL6 protein]
Deferoxamine inhibits the reaction [Asbestos, Amphibole results in increased expression of IL6 mRNA]
CTD PMID:9344885, PMID:22168577, PMID:24296301 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Ireb2 iron responsive element binding protein 2 increases expression
increases activity
multiple interactions
EXP
ISO
Deferoxamine results in increased expression of IREB2 protein
Deferoxamine results in increased activity of IREB2 protein
Deferoxamine inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased activity of IREB2 protein]; Deferoxamine results in increased expression of and results in increased activity of IREB2 protein
CTD PMID:10397746, PMID:11054110, PMID:16135072, PMID:16568477, PMID:17469137, PMID:18073202 NCBI chr 8:59,450,974...59,503,634
Ensembl chr 8:59,420,123...59,501,118
JBrowse link
G Itgb3 integrin subunit beta 3 decreases expression
multiple interactions
ISO Deferoxamine results in decreased expression of ITGB3 mRNA
Deferoxamine inhibits the reaction [TF protein results in increased expression of ITGB3 mRNA]
CTD PMID:31238089 NCBI chr10:92,667,869...92,783,413
Ensembl chr10:92,667,869...92,783,410
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO [Deferoxamine results in decreased abundance of Iron] which results in increased expression of JUN mRNA CTD PMID:12393473 NCBI chr 5:114,011,184...114,014,277
Ensembl chr 5:114,011,189...114,014,277
JBrowse link
G Kdm1a lysine demethylase 1A multiple interactions ISO Deferoxamine results in decreased expression of and results in decreased activity of KDM1A protein CTD PMID:23483119 NCBI chr 5:154,909,003...154,965,171
Ensembl chr 5:154,909,003...154,965,171
JBrowse link
G Kdm3a lysine demethylase 3A increases expression ISO Deferoxamine results in increased expression of KDM3A protein CTD PMID:23546878 NCBI chr 4:99,503,160...99,547,315
Ensembl chr 4:99,503,176...99,546,905
JBrowse link
G Kdm4a lysine demethylase 4A multiple interactions ISO Deferoxamine results in decreased expression of and results in decreased activity of KDM4A protein CTD PMID:23483119 NCBI chr 5:136,967,650...137,014,402
Ensembl chr 5:136,967,650...137,014,430
JBrowse link
G Lcn2 lipocalin 2 multiple interactions
increases expression
ISO Deferoxamine affects the reaction [Magnetite Nanoparticles results in increased expression of LCN2 mRNA]; Deferoxamine inhibits the reaction [LCN2 protein results in decreased secretion of VEGFA protein]
Deferoxamine results in increased expression of LCN2 mRNA
CTD PMID:17114340, PMID:23086747 NCBI chr 3:11,414,189...11,417,534
Ensembl chr 3:11,414,186...11,417,546
JBrowse link
G Lep leptin increases expression
increases secretion
ISO
EXP
Deferoxamine results in increased expression of LEP mRNA
Deferoxamine results in increased secretion of LEP protein
CTD PMID:12032628 NCBI chr 4:56,337,695...56,351,818
Ensembl chr 4:56,337,695...56,351,818
JBrowse link
G Lipe lipase E, hormone sensitive type decreases expression ISO Deferoxamine results in decreased expression of LIPE mRNA CTD PMID:12032628 NCBI chr 1:82,248,031...82,266,727
Ensembl chr 1:82,248,046...82,266,727
JBrowse link
G Lox lysyl oxidase multiple interactions ISO [Deferoxamine results in decreased abundance of Iron] which results in increased expression of LOX mRNA CTD PMID:12393473 NCBI chr18:47,500,320...47,577,819
Ensembl chr18:47,500,330...47,577,819
JBrowse link
G Map1lc3a microtubule-associated protein 1 light chain 3 alpha multiple interactions ISO Deferoxamine inhibits the reaction [Hydrogen Peroxide affects the localization of MAP1LC3A protein] CTD PMID:21742779 NCBI chr 3:150,801,289...150,802,935
Ensembl chr 3:150,801,289...150,802,935
JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta increases expression
multiple interactions
ISO Deferoxamine results in increased expression of MAP1LC3B protein
Deferoxamine inhibits the reaction [di-n-propyldithiocarbamate results in increased expression of and results in increased lipidation of MAP1LC3B protein]; Iron affects the reaction [Deferoxamine results in increased expression of MAP1LC3B protein]
CTD PMID:25301941, PMID:32687844 NCBI chr19:53,635,449...53,643,970
Ensembl chr19:53,629,779...53,646,058
JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 multiple interactions ISO Deferoxamine inhibits the reaction [Plant Extracts results in increased phosphorylation of MAP3K5 protein] CTD PMID:20206247 NCBI chr 1:15,412,603...15,613,752
Ensembl chr 1:15,412,603...15,613,746
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
increases phosphorylation
EXP
ISO
Deferoxamine inhibits the reaction [PDGFB protein results in increased phosphorylation of MAPK1 protein]; Deferoxamine promotes the reaction [Manganese results in increased phosphorylation of MAPK1 protein]
Deferoxamine inhibits the reaction [Nitroprusside results in decreased phosphorylation of MAPK1 protein]; GOSR1 protein affects the reaction [Deferoxamine inhibits the reaction [Nitroprusside results in decreased phosphorylation of MAPK1 protein]]
[Deferoxamine co-treated with TNFSF11 protein] results in decreased phosphorylation of MAPK1 protein; Deferoxamine inhibits the reaction [[Hydrogen Peroxide co-treated with TNFSF11 protein] results in increased phosphorylation of MAPK1 protein]
Deferoxamine results in increased phosphorylation of MAPK1 protein
CTD PMID:11933051, PMID:16527254, PMID:18032466, PMID:20368581, PMID:31066958, PMID:31238089 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
increases phosphorylation
EXP
ISO
Deferoxamine inhibits the reaction [PDGFB protein results in increased phosphorylation of MAPK3 protein]; Deferoxamine promotes the reaction [Manganese results in increased phosphorylation of MAPK3 protein]
Deferoxamine inhibits the reaction [Nitroprusside results in decreased phosphorylation of MAPK3 protein]; GOSR1 protein affects the reaction [Deferoxamine inhibits the reaction [Nitroprusside results in decreased phosphorylation of MAPK3 protein]]
[Deferoxamine co-treated with TNFSF11 protein] results in decreased phosphorylation of MAPK3 protein; Deferoxamine inhibits the reaction [[Hydrogen Peroxide co-treated with TNFSF11 protein] results in increased phosphorylation of MAPK3 protein]
Deferoxamine results in increased phosphorylation of MAPK3 protein
CTD PMID:11933051, PMID:16527254, PMID:18032466, PMID:20368581, PMID:31066958, PMID:31238089 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 increases phosphorylation
multiple interactions
ISO Deferoxamine results in increased phosphorylation of MAPK8 protein
Deferoxamine inhibits the reaction [Plant Extracts results in increased phosphorylation of MAPK8 protein]
CTD PMID:20206247, PMID:20368581 NCBI chr16:9,620,854...9,709,342
Ensembl chr16:9,625,177...9,709,347
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 increases phosphorylation
multiple interactions
ISO Deferoxamine results in increased phosphorylation of MAPK9 protein
Deferoxamine inhibits the reaction [Plant Extracts results in increased phosphorylation of MAPK9 protein]
CTD PMID:20206247, PMID:20368581 NCBI chr10:35,333,859...35,374,364
Ensembl chr10:35,333,859...35,374,355
JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member multiple interactions
increases cleavage
ISO Nitroprusside inhibits the reaction [Deferoxamine results in increased cleavage of MCL1 protein]; Vanadates inhibits the reaction [Deferoxamine results in increased cleavage of MCL1 protein] CTD PMID:16374551 NCBI chr 2:197,786,212...197,788,992 JBrowse link
G Mir210 microRNA 210 increases expression ISO Deferoxamine results in increased expression of MIR210 mRNA CTD PMID:24577088 NCBI chr 1:214,208,355...214,208,464 JBrowse link
G Mmp1 matrix metallopeptidase 1 multiple interactions ISO [Deferoxamine co-treated with SOD2 protein] results in increased expression of MMP1 mRNA; Deferoxamine inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of MMP1 mRNA]; Deferoxamine inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of MMP1 protein]; Deferoxamine inhibits the reaction [[Amitrole co-treated with SOD2 protein] results in increased expression of MMP1 mRNA]; Deferoxamine inhibits the reaction [[Buthionine Sulfoximine co-treated with SOD2 protein] results in increased expression of MMP1 mRNA] CTD PMID:10464329, PMID:19136476 NCBI chr 8:5,703,206...5,723,593
Ensembl chr 8:5,703,206...5,723,591
JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions
decreases activity
ISO Calcium Chloride inhibits the reaction [Deferoxamine results in decreased activity of MMP2 protein]; Deferoxamine inhibits the reaction [ferumoxides results in increased activity of MMP2 protein]; ferric chloride inhibits the reaction [Deferoxamine results in decreased activity of MMP2 protein] CTD PMID:10086886, PMID:20338187 NCBI chr19:15,542,771...15,570,589
Ensembl chr19:15,542,765...15,570,611
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions
decreases expression
ISO Deferoxamine inhibits the reaction [TF protein results in increased expression of MMP9 mRNA]; TF protein affects the reaction [Deferoxamine results in increased expression of MMP9 mRNA]
Deferoxamine results in decreased expression of MMP9 mRNA
CTD PMID:31238089 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Mrps9 mitochondrial ribosomal protein S9 multiple interactions
increases expression
ISO ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of MRPS9 protein] CTD PMID:19515424 NCBI chr 9:49,647,257...49,704,828
Ensembl chr 9:49,647,257...49,704,828
JBrowse link
G Msr1 macrophage scavenger receptor 1 multiple interactions ISO Deferoxamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MSR1 mRNA] CTD PMID:9614211 NCBI chr16:56,817,714...56,900,025
Ensembl chr16:56,813,791...56,900,052
JBrowse link
G Mt-atp6 mitochondrially encoded ATP synthase membrane subunit 6 decreases expression ISO Deferoxamine results in decreased expression of ATP6 mRNA CTD PMID:31238089 NCBI chr MT:7,919...8,599
Ensembl chr MT:7,919...8,599
JBrowse link
G Mt-atp8 mitochondrially encoded ATP synthase membrane subunit 8 decreases expression ISO Deferoxamine results in decreased expression of ATP8 mRNA CTD PMID:31238089 NCBI chr MT:7,758...7,961
Ensembl chr MT:7,758...7,961
JBrowse link
G Mt-co1 mitochondrially encoded cytochrome c oxidase I decreases expression ISO Deferoxamine results in decreased expression of COX1 mRNA CTD PMID:31238089 NCBI chr MT:5,323...6,867
Ensembl chr MT:5,323...6,867
JBrowse link
G Mt-co2 mitochondrially encoded cytochrome c oxidase II decreases expression ISO Deferoxamine results in decreased expression of COX2 mRNA CTD PMID:31238089 NCBI chr MT:7,006...7,689
Ensembl chr MT:7,006...7,689
JBrowse link
G Mt-co3 mitochondrially encoded cytochrome c oxidase III decreases expression ISO Deferoxamine results in decreased expression of COX3 mRNA CTD PMID:31238089 NCBI chr MT:8,599...9,382
Ensembl chr MT:8,599...9,382
JBrowse link
G Mt-cyb mitochondrially encoded cytochrome b decreases expression ISO Deferoxamine results in decreased expression of CYTB mRNA CTD PMID:31238089 NCBI chr MT:14,136...15,278
Ensembl chr MT:14,136...15,278
JBrowse link
G Mt-nd1 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 1 decreases expression ISO Deferoxamine results in decreased expression of ND1 mRNA CTD PMID:31238089 NCBI chr MT:2,740...3,694
Ensembl chr MT:2,740...3,694
JBrowse link
G Mt-nd2 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 2 decreases expression ISO Deferoxamine results in decreased expression of ND2 mRNA CTD PMID:31238089 NCBI chr MT:3,904...4,942
Ensembl chr MT:3,904...4,942
JBrowse link
G Mt-nd3 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 3 decreases expression ISO Deferoxamine results in decreased expression of ND3 mRNA CTD PMID:31238089 NCBI chr MT:9,451...9,798
Ensembl chr MT:9,451...9,798
JBrowse link
G Mt-nd4 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 4 decreases expression ISO Deferoxamine results in decreased expression of ND4 mRNA CTD PMID:31238089 NCBI chr MT:10,160...11,537
Ensembl chr MT:10,160...11,537
JBrowse link
G Mt-nd4l mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 4L decreases expression ISO Deferoxamine results in decreased expression of ND4L mRNA CTD PMID:31238089 NCBI chr MT:9,870...10,166
Ensembl chr MT:9,870...10,166
JBrowse link
G Mt-nd5 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 5 decreases expression ISO Deferoxamine results in decreased expression of ND5 mRNA CTD PMID:31238089 NCBI chr MT:11,736...13,565
Ensembl chr MT:11,736...13,565
JBrowse link
G Mt-nd6 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 6 decreases expression ISO Deferoxamine results in decreased expression of ND6 mRNA CTD PMID:31238089 NCBI chr MT:13,543...14,061
Ensembl chr MT:13,543...14,061
JBrowse link
G Mt2A metallothionein 2A multiple interactions ISO [Deferoxamine results in decreased abundance of Iron] which results in increased expression of MT2A mRNA CTD PMID:12393473 NCBI chr19:11,307,966...11,308,740
Ensembl chr19:11,307,967...11,308,740
JBrowse link
G Muc5ac mucin 5AC, oligomeric mucus/gel-forming multiple interactions ISO Deferoxamine inhibits the reaction [ELANE protein results in increased expression of MUC5AC mRNA] CTD PMID:11919081 NCBI chr 1:214,725,482...214,756,653 JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor increases degradation
decreases expression
multiple interactions
ISO Deferoxamine results in increased degradation of MYC protein
Deferoxamine results in decreased expression of MYC protein
[Deferoxamine results in decreased abundance of Iron] which results in decreased expression of MYC mRNA
CTD PMID:12393473, PMID:20046830, PMID:22245592 NCBI chr 7:102,586,313...102,591,240
Ensembl chr 7:102,586,313...102,591,240
JBrowse link
G Ncoa4 nuclear receptor coactivator 4 multiple interactions ISO Deferoxamine inhibits the reaction [di-n-propyldithiocarbamate results in increased expression of NCOA4 protein]; Deferoxamine promotes the reaction [Palmitic Acid results in increased expression of NCOA4 protein] CTD PMID:32283200, PMID:32687844 NCBI chr16:8,302,950...8,323,294
Ensembl chr16:8,302,950...8,323,293
JBrowse link
G Ndrg1 N-myc downstream regulated 1 increases expression
decreases response to substance
ISO Deferoxamine results in increased expression of NDRG1 mRNA; Deferoxamine results in increased expression of NDRG1 protein
NDRG1 protein results in decreased susceptibility to Deferoxamine
CTD PMID:11006124, PMID:24532803 NCBI chr 7:107,734,326...107,775,701
Ensembl chr 7:107,734,323...107,775,714
JBrowse link
G Ndufb8 NADH:ubiquinone oxidoreductase subunit B8 decreases expression ISO Deferoxamine results in decreased expression of NDUFB8 protein CTD PMID:31238089 NCBI chr 1:264,298,671...264,303,712
Ensembl chr 1:264,298,669...264,303,762
JBrowse link
G Nes nestin decreases expression ISO Deferoxamine results in decreased expression of NES mRNA CTD PMID:16772336 NCBI chr 2:187,343,109...187,352,972
Ensembl chr 2:187,344,056...187,352,969
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 multiple interactions ISO Deferoxamine inhibits the reaction [Nitroprusside results in decreased expression of NFE2L2 protein]; Deferoxamine inhibits the reaction [phenethyl isothiocyanate results in increased expression of and affects the localization of NFE2L2 protein]; ferrous sulfate inhibits the reaction [Deferoxamine inhibits the reaction [Ethacrynic Acid affects the localization of NFE2L2 protein]]; ferrous sulfate inhibits the reaction [Deferoxamine inhibits the reaction [phenethyl isothiocyanate results in increased expression of and affects the localization of NFE2L2 protein]]
Deferoxamine inhibits the reaction [Busulfan results in decreased expression of NFE2L2 protein]
CTD PMID:26945724, PMID:31066958, PMID:32416107 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions EXP Deferoxamine inhibits the reaction [Copper Sulfate results in increased expression of NFKBIA mRNA] CTD PMID:30431687 NCBI chr 6:76,267,227...76,270,457
Ensembl chr 6:76,267,228...76,270,457
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions
increases expression
EXP
ISO
Nitrites inhibits the reaction [[TNF protein results in increased activity of NOS2 protein] which results in increased chemical synthesis of Deferoxamine]
[Deferoxamine results in increased expression of NOS2 mRNA] which results in increased abundance of Nitric Oxide
CTD PMID:7532384, PMID:18073202 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 decreases expression
multiple interactions
ISO Deferoxamine results in decreased expression of NQO1 mRNA
Deferoxamine inhibits the reaction [Benzo(a)pyrene results in increased expression of NQO1 mRNA]
CTD PMID:14645679 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Olr1 oxidized low density lipoprotein receptor 1 decreases expression ISO Deferoxamine results in decreased expression of OLR1 protein CTD PMID:24170104 NCBI chr 4:163,239,853...163,261,937
Ensembl chr 4:163,239,849...163,261,958
JBrowse link
G P4ha1 prolyl 4-hydroxylase subunit alpha 1 decreases expression
multiple interactions
ISO Deferoxamine results in decreased expression of P4HA1 protein
ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of P4HA1 protein]
CTD PMID:19515424 NCBI chr20:28,920,616...28,972,576
Ensembl chr20:28,920,616...28,971,966
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage
multiple interactions
ISO Deferoxamine results in increased cleavage of PARP1 protein
Indomethacin promotes the reaction [Deferoxamine results in increased cleavage of PARP1 protein]; Sulindac promotes the reaction [Deferoxamine results in increased cleavage of PARP1 protein]
CTD PMID:21882223 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Pdgfa platelet derived growth factor subunit A multiple interactions EXP Deferoxamine inhibits the reaction [Asbestos, Amosite results in increased expression of PDGFA mRNA] CTD PMID:11306436 NCBI chr12:17,734,141...17,756,186
Ensembl chr12:17,734,133...17,755,285
JBrowse link
G Pdgfb platelet derived growth factor subunit B multiple interactions EXP Deferoxamine inhibits the reaction [PDGFB protein results in increased phosphorylation of AKT1 protein]; Deferoxamine inhibits the reaction [PDGFB protein results in increased phosphorylation of MAPK1 protein]; Deferoxamine inhibits the reaction [PDGFB protein results in increased phosphorylation of MAPK3 protein] CTD PMID:18032466 NCBI chr 7:121,215,458...121,233,092
Ensembl chr 7:121,214,628...121,232,741
JBrowse link
G Pdgfrb platelet derived growth factor receptor beta decreases expression EXP Deferoxamine results in decreased expression of PDGFRB protein CTD PMID:18032466 NCBI chr18:56,364,586...56,406,381
Ensembl chr18:56,364,620...56,406,381
JBrowse link
G Pdhb pyruvate dehydrogenase E1 subunit beta increases expression
multiple interactions
ISO Deferoxamine results in increased expression of PDHB protein
ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of PDHB protein]
CTD PMID:19515424 NCBI chr15:18,540,826...18,546,855
Ensembl chr15:18,539,210...18,546,854
JBrowse link
G Pdk1 pyruvate dehydrogenase kinase 1 increases expression ISO Deferoxamine results in increased expression of PDK1 mRNA CTD PMID:21558026 NCBI chr 3:58,530,870...58,561,494
Ensembl chr 3:58,530,870...58,558,027
JBrowse link
G Pfkfb4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 multiple interactions ISO [Deferoxamine results in decreased abundance of Iron] which results in increased expression of PFKFB4 mRNA CTD PMID:16025159 NCBI chr 8:117,733,347...117,776,525
Ensembl chr 8:117,737,117...117,775,386
JBrowse link
G Pgk1 phosphoglycerate kinase 1 multiple interactions
decreases expression
ISO ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of PGK1 protein]
Deferoxamine results in decreased expression of PGK1 protein
CTD PMID:19515424 NCBI chr  X:77,263,399...77,279,373
Ensembl chr  X:77,263,359...77,279,367
JBrowse link
G Plagl2 PLAG1 like zinc finger 2 multiple interactions ISO Deferoxamine results in increased expression of and affects the localization of PLAGL2 protein CTD PMID:11832486 NCBI chr 3:148,709,564...148,722,777
Ensembl chr 3:148,709,531...148,722,742
JBrowse link
G Plau plasminogen activator, urokinase multiple interactions ISO Deferoxamine inhibits the reaction [ferric nitrilotriacetate results in increased activity of PLAU mRNA]; Deferoxamine inhibits the reaction [ferric nitrilotriacetate results in increased expression of PLAU mRNA] CTD PMID:17571974 NCBI chr15:3,644,296...3,650,765
Ensembl chr15:3,644,769...3,650,819
JBrowse link
G Pmp22 peripheral myelin protein 22 multiple interactions ISO [Deferoxamine results in decreased abundance of Iron] which results in decreased expression of PMP22 mRNA CTD PMID:12393473 NCBI chr10:49,538,588...49,568,583
Ensembl chr10:49,538,588...49,568,583
JBrowse link
G Ppia peptidylprolyl isomerase A multiple interactions
decreases expression
ISO ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of PPIA protein]
Deferoxamine results in decreased expression of PPIA protein
CTD PMID:19515424 NCBI chr14:86,673,775...86,677,443
Ensembl chr14:86,673,775...86,677,443
JBrowse link
G Prkcd protein kinase C, delta increases phosphorylation ISO Deferoxamine results in increased phosphorylation of PRKCD protein CTD PMID:17097691 NCBI chr16:6,655,131...6,675,746
Ensembl chr16:6,655,120...6,675,746
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases stability
increases expression
multiple interactions
ISO Deferoxamine results in increased stability of PTGS2 protein
Deferoxamine results in increased expression of PTGS2 mRNA; Deferoxamine results in increased expression of PTGS2 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Deferoxamine results in increased expression of PTGS2 protein]; [Sulindac co-treated with Deferoxamine] results in increased expression of PTGS2 protein; ferric citrate inhibits the reaction [Deferoxamine results in increased expression of PTGS2 protein]; Indomethacin promotes the reaction [Deferoxamine results in increased expression of PTGS2 protein]; TP53 gene mutant form promotes the reaction [Deferoxamine results in increased expression of PTGS2 protein]
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Deferoxamine results in increased expression of PTGS2 protein]; ferric citrate inhibits the reaction [Deferoxamine results in increased expression of PTGS2 protein]
CTD PMID:16527254, PMID:21882223 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Rack1 receptor for activated C kinase 1 decreases expression
multiple interactions
ISO Deferoxamine results in decreased expression of RACK1 protein
ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of RACK1 protein]
CTD PMID:19515424 NCBI chr10:34,149,717...34,155,198
Ensembl chr10:34,149,717...34,155,198
Ensembl chr12:34,149,717...34,155,198
JBrowse link
G Ramp2 receptor activity modifying protein 2 decreases expression ISO Deferoxamine results in decreased expression of RAMP2 mRNA CTD PMID:11754965 NCBI chr10:89,166,170...89,168,962
Ensembl chr10:89,166,890...89,168,965
JBrowse link
G Rb1 RB transcriptional corepressor 1 decreases phosphorylation ISO Deferoxamine results in decreased phosphorylation of RB1 protein CTD PMID:11468187 NCBI chr15:55,081,582...55,209,060
Ensembl chr15:55,083,140...55,209,342
JBrowse link
G Runx2 RUNX family transcription factor 2 decreases expression ISO Deferoxamine results in decreased expression of RUNX2 mRNA CTD PMID:16772336 NCBI chr 9:18,564,743...18,773,092
Ensembl chr 9:18,564,927...18,773,092
JBrowse link
G Sag S-antigen visual arrestin multiple interactions EXP Deferoxamine inhibits the reaction [SAG results in increased abundance of Free Radicals] CTD PMID:8407215 NCBI chr 9:94,926,901...94,972,162
Ensembl chr 9:94,928,489...94,972,027
JBrowse link
G Sdhb succinate dehydrogenase complex iron sulfur subunit B decreases expression ISO Deferoxamine results in decreased expression of SDHB protein CTD PMID:31238089 NCBI chr 5:159,484,378...159,505,063
Ensembl chr 5:159,484,370...159,505,064
JBrowse link
G Sele selectin E multiple interactions ISO [Deferoxamine affects the abundance of Iron] inhibits the reaction [TNF protein results in increased expression of SELE mRNA]; [Deferoxamine affects the abundance of Iron] inhibits the reaction [TNF protein results in increased expression of SELE protein] CTD PMID:12633744 NCBI chr13:82,355,234...82,365,323
Ensembl chr13:82,355,471...82,365,341
JBrowse link
G Sesn2 sestrin 2 multiple interactions ISO Deferoxamine inhibits the reaction [erastin results in increased expression of SESN2 protein] CTD PMID:31323261 NCBI chr 5:150,684,891...150,703,846
Ensembl chr 5:150,684,133...150,704,117
JBrowse link
G Setd1a SET domain containing 1A, histone lysine methyltransferase increases expression ISO Deferoxamine results in increased expression of SETD1A mRNA CTD PMID:23483119 NCBI chr 1:199,222,584...199,247,993
Ensembl chr 1:199,225,100...199,247,988
JBrowse link
G Setd2 SET domain containing 2, histone lysine methyltransferase increases expression
affects expression
ISO Deferoxamine results in increased expression of SETD2 mRNA
Deferoxamine affects the expression of SETD2 mRNA
CTD PMID:23483119 NCBI chr 8:118,802,478...118,888,224
Ensembl chr 8:118,803,075...118,888,224
JBrowse link
G Sirt1 sirtuin 1 increases expression ISO Deferoxamine results in increased expression of SIRT1 protein CTD PMID:22245592 NCBI chr20:26,831,971...26,851,587
Ensembl chr20:26,833,357...26,852,199
JBrowse link
G Slc11a2 solute carrier family 11 member 2 multiple interactions
decreases expression
increases expression
EXP
ISO
[Deferoxamine co-treated with Manganese] results in increased expression of SLC11A2; [Deferoxamine promotes the reaction [Doxorubicin results in increased expression of SLC11A2 protein]] which results in increased uptake of Copper; Deferoxamine promotes the reaction [Doxorubicin results in increased expression of SLC11A2 mRNA]; Deferoxamine promotes the reaction [Doxorubicin results in increased expression of SLC11A2 protein]
Deferoxamine results in decreased expression of SLC11A2 mRNA
Deferoxamine results in increased expression of SLC11A2 protein
[Deferoxamine results in decreased abundance of Iron] which results in increased expression of SLC11A2 mRNA; [Deferoxamine results in increased expression of SLC11A2 protein] which results in increased uptake of Manganese; Deferoxamine promotes the reaction [Deferoxamine results in increased expression of SLC11A2 protein]
CTD PMID:11933051, PMID:12393473, PMID:23764342, PMID:24089420 NCBI chr 7:142,025,812...142,062,892
Ensembl chr 7:142,025,815...142,063,212
JBrowse link
G Slc2a1 solute carrier family 2 member 1 multiple interactions
increases expression
ISO [Deferoxamine results in decreased abundance of Oxygen] which results in increased expression of SLC2A1 protein
Deferoxamine results in increased expression of SLC2A1 mRNA
CTD PMID:12032628, PMID:17442736, PMID:21558026 NCBI chr 5:138,154,677...138,182,897
Ensembl chr 5:138,154,673...138,182,897
JBrowse link
G Slc2a4 solute carrier family 2 member 4 decreases expression ISO Deferoxamine results in decreased expression of SLC2A4 mRNA CTD PMID:12032628 NCBI chr10:56,552,921...56,558,562
Ensembl chr10:56,552,983...56,558,487
JBrowse link
G Slc40a1 solute carrier family 40 member 1 increases expression
multiple interactions
ISO Deferoxamine results in increased expression of SLC40A1 protein
Deferoxamine inhibits the reaction [Busulfan results in decreased expression of SLC40A1 protein]
CTD PMID:31238089, PMID:32416107 NCBI chr 9:52,819,451...52,830,461
Ensembl chr 9:52,894,365...52,912,293
JBrowse link
G Slc6a2 solute carrier family 6 member 2 decreases expression EXP Deferoxamine results in decreased expression of SLC6A2 protein CTD PMID:16650837 NCBI chr19:15,391,682...15,431,274
Ensembl chr19:15,391,581...15,431,274
JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions
increases expression
ISO [Deferoxamine co-treated with SOD2 protein] results in increased expression of MMP1 mRNA; Deferoxamine inhibits the reaction [[Amitrole co-treated with SOD2 protein] results in increased expression of MMP1 mRNA]; Deferoxamine inhibits the reaction [[Buthionine Sulfoximine co-treated with SOD2 protein] results in increased expression of MMP1 mRNA]; TRAP1 protein inhibits the reaction [Deferoxamine results in increased expression of SOD2 protein]
Deferoxamine inhibits the reaction [SOD2 protein affects the reaction [Ethanol results in increased abundance of Iron]]
CTD PMID:10464329, PMID:16927372, PMID:19063909 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
JBrowse link
G Sp1 Sp1 transcription factor multiple interactions ISO [Deferoxamine affects the abundance of Iron] inhibits the reaction [TNF protein results in increased activity of SP1 protein] CTD PMID:12633744 NCBI chr 7:144,014,173...144,044,635
Ensembl chr 7:144,014,173...144,044,629
JBrowse link
G Sp7 Sp7 transcription factor multiple interactions ISO Deferoxamine inhibits the reaction [Ascorbic Acid results in increased expression of SP7 mRNA] CTD PMID:21467157 NCBI chr 7:143,957,316...143,967,488
Ensembl chr 7:143,958,858...143,967,484
JBrowse link
G Sqstm1 sequestosome 1 increases expression
multiple interactions
ISO Deferoxamine results in increased expression of SQSTM1 protein
[Copper co-treated with Deferoxamine] results in increased expression of SQSTM1 protein; [Iron co-treated with Deferoxamine] results in increased expression of SQSTM1 protein; Deferoxamine promotes the reaction [Palmitic Acid results in increased expression of SQSTM1 protein]
CTD PMID:25301941, PMID:32283200 NCBI chr10:35,704,728...35,716,316
Ensembl chr10:35,704,730...35,716,294
JBrowse link
G St6gal1 ST6 beta-galactoside alpha-2,6-sialyltransferase 1 multiple interactions ISO ST6GAL1 protein promotes the reaction [Deferoxamine results in increased expression of HIF1A protein] CTD PMID:29475939 NCBI chr11:80,927,601...80,981,424
Ensembl chr11:80,927,601...80,981,422
JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions EXP Deferoxamine inhibits the reaction [Copper Sulfate results in increased expression of STAT3 protein] CTD PMID:30431687 NCBI chr10:88,790,401...88,842,263
Ensembl chr10:88,790,408...88,842,233
JBrowse link
G Suv39h1 suppressor of variegation 3-9 homolog 1 decreases expression
increases expression
ISO Deferoxamine results in decreased expression of SUV39H1 mRNA
Deferoxamine results in increased expression of SUV39H1 mRNA
CTD PMID:23483119 NCBI chr  X:146,532,002...146,533,538 JBrowse link
G Tet2 tet methylcytosine dioxygenase 2 decreases expression ISO Deferoxamine results in decreased expression of TET2 protein CTD PMID:23483119 NCBI chr 2:238,719,389...238,802,975
Ensembl chr 2:238,720,835...238,803,024
JBrowse link
G Tf transferrin multiple interactions ISO Deferoxamine affects the reaction [TF protein affects the expression of ATP6V0D2 mRNA]; Deferoxamine inhibits the reaction [TF protein results in increased activity of ACP5 protein]; Deferoxamine inhibits the reaction [TF protein results in increased expression of CTSK mRNA]; Deferoxamine inhibits the reaction [TF protein results in increased expression of ITGB3 mRNA]; Deferoxamine inhibits the reaction [TF protein results in increased expression of MMP9 mRNA]; TF protein affects the reaction [Deferoxamine affects the expression of ATP6V0D2 mRNA]; TF protein affects the reaction [Deferoxamine results in decreased expression of CTSK mRNA]; TF protein affects the reaction [Deferoxamine results in increased expression of MMP9 mRNA]; TF protein inhibits the reaction [Deferoxamine results in decreased activity of ACP5 protein] CTD PMID:31238089 NCBI chr 8:111,694,570...111,721,275
Ensembl chr 8:111,673,547...111,721,333
JBrowse link
G Tfr2 transferrin receptor 2 decreases expression ISO Deferoxamine results in decreased expression of TFR2 protein CTD PMID:25633564 NCBI chr12:22,177,382...22,194,330
Ensembl chr12:22,177,382...22,194,299
JBrowse link
G Tfrc transferrin receptor increases expression
multiple interactions
ISO
EXP
Deferoxamine results in increased expression of TFRC mRNA; Deferoxamine results in increased expression of TFRC protein
Deferoxamine inhibits the reaction [Doxorubicin results in decreased expression of TFRC mRNA]
Deferoxamine affects the reaction [Magnetite Nanoparticles results in decreased expression of TFRC mRNA]; Deferoxamine promotes the reaction [Busulfan results in decreased expression of TFRC protein]
[Deferoxamine results in decreased abundance of Iron] which results in increased expression of TFRC mRNA; [Deferoxamine results in decreased abundance of Oxygen] which results in increased expression of TFRC protein
CTD PMID:11054110, PMID:12393473, PMID:12807743, PMID:15993339, PMID:16039939, PMID:16568477, PMID:16760464, PMID:17442736, PMID:17469137, PMID:18073202, PMID:23086747, PMID:24089420, PMID:31238089, PMID:32416107 NCBI chr11:71,397,423...71,419,263
Ensembl chr11:71,397,383...71,419,223
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions EXP Deferoxamine inhibits the reaction [Asbestos, Amosite results in increased expression of TGFB1 mRNA] CTD PMID:11306436 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Th tyrosine hydroxylase increases expression EXP Deferoxamine results in increased expression of TH mRNA CTD PMID:9458725 NCBI chr 1:216,073,034...216,080,287
Ensembl chr 1:216,073,031...216,080,287
JBrowse link
G Tlr4 toll-like receptor 4 decreases expression ISO Deferoxamine results in decreased expression of TLR4 protein CTD PMID:24170104 NCBI chr 5:82,587,424...82,601,056
Ensembl chr 5:82,587,420...82,601,052
JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases response to substance
decreases expression
decreases activity
ISO
EXP
[Deferoxamine affects the abundance of Iron] inhibits the reaction [TNF protein results in increased activity of SP1 protein]; [Deferoxamine affects the abundance of Iron] inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]; [Deferoxamine affects the abundance of Iron] inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]; [Deferoxamine affects the abundance of Iron] inhibits the reaction [TNF protein results in increased expression of SELE mRNA]; [Deferoxamine affects the abundance of Iron] inhibits the reaction [TNF protein results in increased expression of SELE protein]; [Deferoxamine affects the abundance of Iron] inhibits the reaction [TNF protein results in increased expression of VCAM1 mRNA]; [Deferoxamine affects the abundance of Iron] inhibits the reaction [TNF protein results in increased expression of VCAM1 protein]; Deferoxamine inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; Deferoxamine inhibits the reaction [Particulate Matter results in increased expression of TNF mRNA]; ferrous sulfate inhibits the reaction [Deferoxamine results in decreased activity of TNF protein]
Deferoxamine inhibits the reaction [Asbestos, Crocidolite results in increased secretion of TNF protein]
Deferoxamine results in increased susceptibility to TNF protein
Deferoxamine inhibits the reaction [Asbestos, Crocidolite results in increased secretion of TNF protein]; Nitrites inhibits the reaction [[TNF protein results in increased activity of NOS2 protein] which results in increased chemical synthesis of Deferoxamine]
Deferoxamine results in decreased expression of TNF mRNA
CTD PMID:7532384, PMID:7539275, PMID:9851740, PMID:10486238, PMID:12633744, PMID:15550384, PMID:16910777, PMID:20801209 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tnfrsf11a TNF receptor superfamily member 11A decreases expression ISO Deferoxamine results in decreased expression of TNFRSF11A mRNA CTD PMID:31238089 NCBI chr13:25,778,306...25,835,802
Ensembl chr13:25,778,317...25,835,957
JBrowse link
G Tnfsf11 TNF superfamily member 11 multiple interactions ISO [Deferoxamine co-treated with TNFSF11 protein] results in decreased phosphorylation of MAPK1 protein; [Deferoxamine co-treated with TNFSF11 protein] results in decreased phosphorylation of MAPK3 protein; Deferoxamine inhibits the reaction [[Hydrogen Peroxide co-treated with TNFSF11 protein] results in increased phosphorylation of MAPK1 protein]; Deferoxamine inhibits the reaction [[Hydrogen Peroxide co-treated with TNFSF11 protein] results in increased phosphorylation of MAPK3 protein] CTD PMID:31238089 NCBI chr15:60,482,527...60,512,704
Ensembl chr15:60,482,527...60,512,704
JBrowse link
G Tp53 tumor protein p53 multiple interactions
increases expression
decreases response to substance
ISO Deferoxamine inhibits the reaction [Asbestos, Amosite results in increased expression of TP53 mRNA]; Deferoxamine inhibits the reaction [sodium bichromate results in increased expression of TP53 protein]; TP53 gene mutant form promotes the reaction [Deferoxamine results in increased expression of HIF1A protein]; TP53 gene mutant form promotes the reaction [Deferoxamine results in increased expression of PTGS2 protein]
Deferoxamine results in increased expression of TP53 protein
TP53 protein results in decreased susceptibility to Deferoxamine
CTD PMID:10942736, PMID:16357363, PMID:16527254, PMID:23483119 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Tpd52l1 TPD52 like 1 decreases expression
multiple interactions
ISO Deferoxamine results in decreased expression of TPD52L1 protein
ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of TPD52L1 protein]
CTD PMID:19515424 NCBI chr 1:28,454,949...28,578,736
Ensembl chr 1:28,454,966...28,576,553
JBrowse link
G Tpi1 triosephosphate isomerase 1 increases expression EXP Deferoxamine results in increased expression of TPI1 mRNA CTD PMID:14762718 NCBI chr 4:157,328,375...157,331,905
Ensembl chr 4:157,328,379...157,331,905
JBrowse link
G Trap1 TNF receptor-associated protein 1 decreases expression
multiple interactions
ISO Deferoxamine results in decreased expression of TRAP1 mRNA; Deferoxamine results in decreased expression of TRAP1 protein
TRAP1 protein inhibits the reaction [Deferoxamine results in increased expression of SOD2 protein]
CTD PMID:16927372 NCBI chr10:11,724,032...11,757,682
Ensembl chr10:11,724,032...11,757,681
JBrowse link
G Tubb3 tubulin, beta 3 class III increases expression ISO Deferoxamine results in increased expression of TUBB3 mRNA CTD PMID:16772336 NCBI chr19:56,220,759...56,229,813
Ensembl chr19:56,220,755...56,229,813
JBrowse link
G Ucp2 uncoupling protein 2 decreases expression ISO Deferoxamine results in decreased expression of UCP2 mRNA CTD PMID:12032628 NCBI chr 1:165,506,375...165,512,744
Ensembl chr 1:165,506,361...165,512,744
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 multiple interactions ISO
EXP
[Deferoxamine affects the abundance of Iron] inhibits the reaction [TNF protein results in increased expression of VCAM1 mRNA]; [Deferoxamine affects the abundance of Iron] inhibits the reaction [TNF protein results in increased expression of VCAM1 protein]
Deferoxamine inhibits the reaction [Copper Sulfate results in increased expression of VCAM1 protein]
CTD PMID:12633744, PMID:30431687 NCBI chr 2:219,071,193...219,090,931
Ensembl chr 2:219,071,193...219,097,619
JBrowse link
G Vdac2 voltage-dependent anion channel 2 multiple interactions
decreases expression
ISO ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of VDAC2 protein]
Deferoxamine results in decreased expression of VDAC2 protein
CTD PMID:19515424 NCBI chr15:2,634,622...2,648,548
Ensembl chr15:2,634,624...2,648,551
JBrowse link
G Vdr vitamin D receptor increases expression ISO Deferoxamine results in increased expression of VDR mRNA CTD PMID:20368581 NCBI chr 7:139,344,452...139,394,138
Ensembl chr 7:139,342,063...139,394,166
JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions
increases expression
increases secretion
ISO
EXP
Deferoxamine inhibits the reaction [LCN2 protein results in decreased secretion of VEGFA protein]
Deferoxamine results in increased expression of VEGFA mRNA
Deferoxamine results in increased expression of VEGFA mRNA; Deferoxamine results in increased expression of VEGFA protein
Deferoxamine promotes the reaction [[HIF1A protein binds to VEGFA promoter] which results in increased expression of VEGFA mRNA]; Deferoxamine promotes the reaction [Potassium Dichromate results in increased expression of VEGFA protein]
Deferoxamine results in increased secretion of VEGFA protein
CTD PMID:10613739, PMID:12213806, PMID:15075239, PMID:16227210, PMID:17114340, PMID:19695866, PMID:21558026 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681
JBrowse link
G Vhl von Hippel-Lindau tumor suppressor multiple interactions ISO VHL protein mutant form affects the reaction [Deferoxamine results in decreased susceptibility to Hydrogen Peroxide] CTD PMID:18515279 NCBI chr 4:145,580,869...145,587,835
Ensembl chr 4:145,580,799...145,587,845
JBrowse link
G Wt1 WT1 transcription factor multiple interactions ISO [cobaltous chloride co-treated with Deferoxamine] results in increased expression of WT1 mRNA CTD PMID:12738801 NCBI chr 3:95,133,221...95,180,574
Ensembl chr 3:95,133,713...95,180,564
JBrowse link
G Xbp1 X-box binding protein 1 multiple interactions ISO Deferoxamine promotes the reaction [Palmitic Acid results in increased expression of XBP1 protein] CTD PMID:32283200 NCBI chr14:85,753,736...85,758,820
Ensembl chr14:85,753,760...85,758,145
JBrowse link
dinophysistoxin 1 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abtb2 ankyrin repeat and BTB domain containing 2 increases expression ISO dinophysistoxin 1 results in increased expression of ABTB2 mRNA CTD PMID:28939011 NCBI chr 3:93,494,706...93,648,750
Ensembl chr 3:93,495,106...93,647,721
JBrowse link
G Aldoc aldolase, fructose-bisphosphate C increases expression ISO dinophysistoxin 1 results in increased expression of ALDOC mRNA CTD PMID:28939011 NCBI chr10:65,586,504...65,590,093
Ensembl chr10:65,586,504...65,590,126
JBrowse link
G Atf3 activating transcription factor 3 increases expression ISO dinophysistoxin 1 results in increased expression of ATF3 mRNA CTD PMID:28939011 NCBI chr13:109,817,892...109,849,632
Ensembl chr13:109,817,728...109,849,632
JBrowse link
G Atxn3 ataxin 3 increases expression ISO dinophysistoxin 1 results in increased expression of ATXN3 mRNA CTD PMID:28939011 NCBI chr 6:125,817,420...125,853,461
Ensembl chr 6:125,819,640...125,853,461
JBrowse link
G Bace1 beta-secretase 1 decreases expression ISO dinophysistoxin 1 results in decreased expression of BACE1 mRNA CTD PMID:28939011 NCBI chr 8:50,140,092...50,162,388
Ensembl chr 8:50,139,997...50,162,361
JBrowse link
G Bcl2l11 BCL2 like 11 increases expression ISO dinophysistoxin 1 results in increased expression of BCL2L11 mRNA CTD PMID:28939011 NCBI chr 3:120,726,906...120,764,192
Ensembl chr 3:120,726,906...120,764,192
JBrowse link
G Bfsp1 beaded filament structural protein 1 decreases expression ISO dinophysistoxin 1 results in decreased expression of BFSP1 mRNA CTD PMID:28939011 NCBI chr 3:137,935,345...137,992,652
Ensembl chr 3:137,935,345...137,969,658
JBrowse link
G Bik BCL2-interacting killer increases expression ISO dinophysistoxin 1 results in increased expression of BIK mRNA CTD PMID:28939011 NCBI chr 7:124,390,924...124,410,449
Ensembl chr 7:124,391,432...124,410,447
JBrowse link
G Bpgm bisphosphoglycerate mutase increases expression ISO dinophysistoxin 1 results in increased expression of BPGM mRNA CTD PMID:28939011 NCBI chr 4:61,912,210...61,940,697
Ensembl chr 4:61,912,210...61,940,696
JBrowse link
G Calr calreticulin increases expression ISO dinophysistoxin 1 results in increased expression of CALR mRNA CTD PMID:28939011 NCBI chr19:25,956,771...25,961,666
Ensembl chr19:25,956,771...25,961,666
JBrowse link
G Canx calnexin increases expression ISO dinophysistoxin 1 results in increased expression of CANX mRNA CTD PMID:28939011 NCBI chr10:35,800,942...35,833,939
Ensembl chr10:35,800,942...35,833,861
JBrowse link
G Cck cholecystokinin increases expression ISO dinophysistoxin 1 results in increased expression of CCK mRNA CTD PMID:28939011 NCBI chr 8:130,120,525...130,127,515
Ensembl chr 8:130,120,523...130,127,392
JBrowse link
G Cct4 chaperonin containing TCP1 subunit 4 increases expression ISO dinophysistoxin 1 results in increased expression of CCT4 mRNA CTD PMID:28939011 NCBI chr14:107,767,392...107,780,270
Ensembl chr14:107,767,392...107,780,270
JBrowse link
G Cct7 chaperonin containing TCP1 subunit 7 increases expression ISO dinophysistoxin 1 results in increased expression of CCT7 mRNA CTD PMID:28939011 NCBI chr 4:117,235,023...117,252,265
Ensembl chr 4:117,235,023...117,252,265
JBrowse link
G Cd44 CD44 molecule (Indian blood group) increases expression ISO dinophysistoxin 1 results in increased expression of CD44 mRNA CTD PMID:28939011 NCBI chr 3:92,695,083...92,783,820
Ensembl chr 3:92,696,313...92,783,658
JBrowse link
G Cdkn1c cyclin-dependent kinase inhibitor 1C increases expression ISO dinophysistoxin 1 results in increased expression of CDKN1C mRNA CTD PMID:21853993, PMID:28939011 NCBI chr 1:216,661,067...216,663,791
Ensembl chr 1:216,661,080...216,663,721
JBrowse link
G Ceacam1 CEA cell adhesion molecule 1 increases expression ISO dinophysistoxin 1 results in increased expression of CEACAM1 mRNA CTD PMID:21853993, PMID:28939011 NCBI chr 1:82,327,955...82,344,345
Ensembl chr 1:82,327,955...82,344,345
JBrowse link
G Cebpb CCAAT/enhancer binding protein beta increases expression ISO dinophysistoxin 1 results in increased expression of CEBPB mRNA CTD PMID:28939011 NCBI chr 3:164,424,502...164,425,933
Ensembl chr 3:164,424,515...164,425,910
JBrowse link
G Chrna7 cholinergic receptor nicotinic alpha 7 subunit increases expression ISO dinophysistoxin 1 results in increased expression of CHRNA7 mRNA CTD PMID:28939011 NCBI chr 1:123,897,341...124,039,263
Ensembl chr 1:123,899,657...124,039,196
JBrowse link
G Chst9 carbohydrate sulfotransferase 9 decreases expression ISO dinophysistoxin 1 results in decreased expression of CHST9 mRNA CTD PMID:28939011 NCBI chr18:6,833,408...7,115,815
Ensembl chr18:6,834,365...7,081,356
JBrowse link
G Crebbp CREB binding protein increases expression ISO dinophysistoxin 1 results in increased expression of CREBBP mRNA CTD PMID:28939011 NCBI chr10:11,590,994...11,721,039
Ensembl chr10:11,595,044...11,721,039
JBrowse link
G Creg2 cellular repressor of E1A-stimulated genes 2 decreases expression ISO dinophysistoxin 1 results in decreased expression of CREG2 mRNA CTD PMID:28939011 NCBI chr 9:46,328,088...46,402,237
Ensembl chr 9:46,360,061...46,401,911
JBrowse link
G Cryl1 crystallin, lambda 1 decreases expression ISO dinophysistoxin 1 results in decreased expression of CRYL1 mRNA CTD PMID:28939011 NCBI chr15:37,543,727...37,663,586
Ensembl chr15:37,543,727...37,663,584
JBrowse link
G Cul2 cullin 2 increases expression ISO dinophysistoxin 1 results in increased expression of CUL2 mRNA CTD PMID:28939011 NCBI chr17:56,952,480...56,992,716
Ensembl chr17:56,952,480...56,992,694
JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 increases expression ISO dinophysistoxin 1 results in increased expression of CXCR4 mRNA CTD PMID:28939011 NCBI chr13:45,314,952...45,318,856
Ensembl chr13:45,314,933...45,318,878
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression ISO dinophysistoxin 1 results in increased expression of DDIT3 mRNA CTD PMID:28939011 NCBI chr 7:70,578,564...70,585,074
Ensembl chr 7:70,580,198...70,585,084
JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 increases expression ISO dinophysistoxin 1 results in increased expression of DDIT4 mRNA CTD PMID:21853993 NCBI chr20:29,509,283...29,511,382
Ensembl chr20:29,509,289...29,511,382
JBrowse link
G Depp1 DEPP1, autophagy regulator increases expression ISO dinophysistoxin 1 results in increased expression of DEPP1 mRNA CTD PMID:28939011 NCBI chr 4:148,780,330...148,784,566
Ensembl chr 4:148,782,479...148,784,562
JBrowse link
G Dhcr24 24-dehydrocholesterol reductase decreases expression ISO dinophysistoxin 1 results in decreased expression of DHCR24 mRNA CTD PMID:28939011 NCBI chr 5:126,164,708...126,188,926
Ensembl chr 5:126,164,674...126,191,206
JBrowse link
G Dhtkd1 dehydrogenase E1 and transketolase domain containing 1 decreases expression ISO dinophysistoxin 1 results in decreased expression of DHTKD1 mRNA CTD PMID:28939011 NCBI chr17:76,306,585...76,358,058
Ensembl chr17:76,306,585...76,358,058
JBrowse link
G Dlat dihydrolipoamide S-acetyltransferase increases expression ISO dinophysistoxin 1 results in increased expression of DLAT mRNA CTD PMID:28939011 NCBI chr 8:55,062,549...55,087,832
Ensembl chr 8:55,062,551...55,087,832
JBrowse link
G Dmd dystrophin decreases expression ISO dinophysistoxin 1 results in decreased expression of DMD mRNA CTD PMID:28939011 NCBI chr  X:51,149,358...53,519,271
Ensembl chr  X:51,286,737...53,519,259
JBrowse link
G Dnajb2 DnaJ heat shock protein family (Hsp40) member B2 increases expression ISO dinophysistoxin 1 results in increased expression of DNAJB2 mRNA CTD PMID:28939011 NCBI chr 9:82,436,453...82,444,669
Ensembl chr 9:82,436,458...82,444,668
JBrowse link
G Dnajb9 DnaJ heat shock protein family (Hsp40) member B9 increases expression ISO dinophysistoxin 1 results in increased expression of DNAJB9 mRNA CTD PMID:28939011 NCBI chr 6:64,165,913...64,170,122
Ensembl chr 6:64,165,913...64,170,151
JBrowse link
G Dnajc10 DnaJ heat shock protein family (Hsp40) member C10 increases expression ISO dinophysistoxin 1 results in increased expression of DNAJC10 mRNA CTD PMID:28939011 NCBI chr 3:67,538,289...67,578,308
Ensembl chr 3:67,538,289...67,578,306
JBrowse link
G Dnajc4 DnaJ heat shock protein family (Hsp40) member C4 decreases expression ISO dinophysistoxin 1 results in decreased expression of DNAJC4 mRNA CTD PMID:28939011 NCBI chr 1:222,242,889...222,247,115
Ensembl chr 1:222,242,858...222,246,768
JBrowse link
G Dusp4 dual specificity phosphatase 4 increases expression ISO dinophysistoxin 1 results in increased expression of DUSP4 mRNA CTD PMID:28939011 NCBI chr16:61,080,767...61,090,973
Ensembl chr16:61,078,175...61,091,169
JBrowse link
G Dusp5 dual specificity phosphatase 5 increases expression ISO dinophysistoxin 1 results in increased expression of DUSP5 mRNA CTD PMID:28939011 NCBI chr 1:274,245,184...274,258,595
Ensembl chr 1:274,245,184...274,258,595
JBrowse link
G Egln1 egl-9 family hypoxia-inducible factor 1 increases expression ISO dinophysistoxin 1 results in increased expression of EGLN1 mRNA CTD PMID:28939011 NCBI chr19:57,660,194...57,701,158
Ensembl chr19:57,662,278...57,699,113
JBrowse link
G Egln2 egl-9 family hypoxia-inducible factor 2 increases expression ISO dinophysistoxin 1 results in increased expression of EGLN2 mRNA CTD PMID:28939011 NCBI chr 1:83,969,456...83,977,665
Ensembl chr 1:83,969,457...83,977,236
JBrowse link
G Egln3 egl-9 family hypoxia-inducible factor 3 increases expression ISO dinophysistoxin 1 results in increased expression of EGLN3 mRNA CTD PMID:28939011 NCBI chr 6:75,050,329...75,075,795
Ensembl chr 6:75,050,329...75,075,795
JBrowse link
G Egr1 early growth response 1 increases expression ISO dinophysistoxin 1 results in increased expression of EGR1 mRNA CTD PMID:28939011 NCBI chr18:27,657,903...27,660,101
Ensembl chr18:27,657,628...27,661,429
JBrowse link
G Elob elongin B increases expression ISO dinophysistoxin 1 results in increased expression of ELOB mRNA CTD PMID:28939011 NCBI chr10:13,163,032...13,168,217
Ensembl chr10:13,163,036...13,168,217
JBrowse link
G Eloc elongin C increases expression ISO dinophysistoxin 1 results in increased expression of ELOC mRNA CTD PMID:28939011 NCBI chr 5:2,042,991...2,059,357
Ensembl chr 5:2,042,991...2,059,351
JBrowse link
G Emp1 epithelial membrane protein 1 increases expression ISO dinophysistoxin 1 results in increased expression of EMP1 mRNA CTD PMID:28939011 NCBI chr 4:169,161,076...169,181,967
Ensembl chr 4:169,147,243...169,181,966
JBrowse link
G Eno2 enolase 2 decreases expression ISO dinophysistoxin 1 results in decreased expression of ENO2 mRNA CTD PMID:28939011 NCBI chr 4:157,285,192...157,294,090
Ensembl chr 4:157,285,179...157,294,047
JBrowse link
G Eno3 enolase 3 increases expression ISO dinophysistoxin 1 results in increased expression of ENO3 mRNA CTD PMID:28939011 NCBI chr10:57,278,271...57,283,661
Ensembl chr10:57,278,307...57,283,653
JBrowse link
G Ep300 E1A binding protein p300 affects expression ISO dinophysistoxin 1 affects the expression of EP300 mRNA CTD PMID:28939011 NCBI chr 7:122,818,194...122,889,055
Ensembl chr 7:122,818,975...122,861,296
JBrowse link
G Epas1 endothelial PAS domain protein 1 increases expression ISO dinophysistoxin 1 results in increased expression of EPAS1 mRNA CTD PMID:28939011 NCBI chr 6:10,306,508...10,385,239
Ensembl chr 6:10,306,405...10,387,265
JBrowse link
G Ephx2 epoxide hydrolase 2 decreases expression ISO dinophysistoxin 1 results in decreased expression of EPHX2 mRNA CTD PMID:28939011 NCBI chr15:42,757,241...42,794,211
Ensembl chr15:42,757,235...42,794,279
JBrowse link
G Epsti1 epithelial stromal interaction 1 decreases expression ISO dinophysistoxin 1 results in decreased expression of EPSTI1 mRNA CTD PMID:28939011 NCBI chr15:60,084,966...60,190,360
Ensembl chr15:60,084,918...60,190,363
JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 increases expression ISO dinophysistoxin 1 results in increased expression of ERN1 mRNA CTD PMID:28939011 NCBI chr10:94,588,555...94,682,072
Ensembl chr10:94,588,555...94,681,914
JBrowse link
G Ero1b endoplasmic reticulum oxidoreductase 1 beta increases expression ISO dinophysistoxin 1 results in increased expression of ERO1B mRNA CTD PMID:28939011 NCBI chr17:90,709,394...90,783,110
Ensembl chr17:90,710,555...90,756,048
JBrowse link
G F2rl1 F2R like trypsin receptor 1 increases expression ISO dinophysistoxin 1 results in increased expression of F2RL1 mRNA CTD PMID:28939011 NCBI chr 2:25,222,324...25,235,275
Ensembl chr 2:25,222,328...25,235,275
JBrowse link
G FAM120C family with sequence similarity 120C decreases expression ISO dinophysistoxin 1 results in decreased expression of FAM120C mRNA CTD PMID:28939011 NCBI chr  X:20,481,800...21,016,980
Ensembl chr  X:20,484,517...21,015,836
JBrowse link
G Fdft1 farnesyl diphosphate farnesyl transferase 1 decreases expression ISO dinophysistoxin 1 results in decreased expression of FDFT1 mRNA CTD PMID:28939011 NCBI chr15:46,339,248...46,367,302
Ensembl chr15:46,339,249...46,367,302
JBrowse link
G Fdps farnesyl diphosphate synthase decreases expression ISO dinophysistoxin 1 results in decreased expression of FDPS mRNA CTD PMID:28939011 NCBI chr 2:188,403,595...188,413,219
Ensembl chr 2:188,392,858...188,413,219
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression ISO dinophysistoxin 1 results in increased expression of FOS mRNA CTD PMID:28939011 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Gpc5 glypican 5 decreases expression ISO dinophysistoxin 1 results in decreased expression of GPC5 mRNA CTD PMID:28939011 NCBI chr15:100,283,131...101,776,838 JBrowse link
G Gpi glucose-6-phosphate isomerase affects expression ISO dinophysistoxin 1 affects the expression of GPI mRNA CTD PMID:28939011 NCBI chr 1:90,063,411...90,091,287
Ensembl chr 1:90,063,411...90,091,287
JBrowse link
G Gsta1 glutathione S-transferase alpha 1 decreases expression ISO dinophysistoxin 1 results in decreased expression of GSTA1 mRNA CTD PMID:28939011 NCBI chr 9:27,366,404...27,381,004
Ensembl chr 9:27,368,272...27,452,902
JBrowse link
G Gsta4 glutathione S-transferase alpha 4 decreases expression ISO dinophysistoxin 1 results in decreased expression of GSTA4 mRNA CTD PMID:28939011 NCBI chr 8:85,497,557...85,514,732
Ensembl chr 8:85,497,557...85,518,879
JBrowse link
G Gstk1 glutathione S-transferase kappa 1 decreases expression ISO dinophysistoxin 1 results in decreased expression of GSTK1 mRNA CTD PMID:28939011 NCBI chr 4:71,621,777...71,626,096
Ensembl chr 4:71,621,729...71,626,107
JBrowse link
G Gstm1 glutathione S-transferase mu 1 increases expression ISO dinophysistoxin 1 results in increased expression of GSTM1 mRNA CTD PMID:28939011 NCBI chr 2:210,803,869...210,809,461
Ensembl chr 2:210,803,869...210,809,306
JBrowse link
G Gstm3 glutathione S-transferase mu 3 increases expression ISO dinophysistoxin 1 results in increased expression of GSTM3 mRNA CTD PMID:28939011 NCBI chr 2:210,685,204...210,688,273
Ensembl chr 2:210,685,197...210,688,272
JBrowse link
G Gstm5 glutathione S-transferase, mu 5 increases expression ISO dinophysistoxin 1 results in increased expression of GSTM3 mRNA CTD PMID:28939011 NCBI chr 2:210,685,338...210,688,133
Ensembl chr 2:210,685,197...210,688,272
JBrowse link
G Gstp1 glutathione S-transferase pi 1 increases expression ISO dinophysistoxin 1 results in increased expression of GSTP1 mRNA CTD PMID:28939011 NCBI chr 1:219,291,679...219,294,147
Ensembl chr 1:219,291,679...219,294,147
JBrowse link
G Gstz1 glutathione S-transferase zeta 1 decreases expression ISO dinophysistoxin 1 results in decreased expression of GSTZ1 mRNA CTD PMID:28939011 NCBI chr 6:111,176,798...111,187,246
Ensembl chr 6:111,176,798...111,187,244
JBrowse link
G H1f4 H1.4 linker histone, cluster member decreases expression ISO dinophysistoxin 1 results in decreased expression of H1-4 mRNA CTD PMID:28939011 NCBI chr17:43,734,461...43,735,120
Ensembl chr17:43,734,461...43,735,120
JBrowse link
G Hebp1 heme binding protein 1 decreases expression ISO dinophysistoxin 1 results in decreased expression of HEBP1 mRNA CTD PMID:28939011 NCBI chr 4:168,903,586...168,933,102
Ensembl chr 4:168,903,565...168,933,079
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha affects expression ISO dinophysistoxin 1 affects the expression of HIF1A mRNA CTD PMID:28939011 NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052
JBrowse link
G Hif1an hypoxia inducible factor 1 subunit alpha inhibitor increases expression ISO dinophysistoxin 1 results in increased expression of HIF1AN mRNA CTD PMID:28939011 NCBI chr 1:264,309,214...264,319,269
Ensembl chr 1:264,309,214...264,319,267
JBrowse link
G Hif3a hypoxia inducible factor 3 subunit alpha affects expression ISO dinophysistoxin 1 affects the expression of HIF3A mRNA CTD PMID:28939011 NCBI chr 1:78,976,318...78,997,869
Ensembl chr 1:78,976,318...78,997,869
JBrowse link
G Hk1 hexokinase 1 decreases expression ISO dinophysistoxin 1 results in decreased expression of HK1 mRNA CTD PMID:28939011 NCBI chr20:31,911,460...31,979,780
Ensembl chr20:31,912,262...31,956,649
JBrowse link
G Hk2 hexokinase 2 increases expression ISO dinophysistoxin 1 results in increased expression of HK2 mRNA CTD PMID:28939011 NCBI chr 4:113,559,396...113,609,897
Ensembl chr 4:113,559,427...113,610,243
JBrowse link
G Hmgcl 3-hydroxy-3-methylglutaryl-CoA lyase decreases expression ISO dinophysistoxin 1 results in decreased expression of HMGCL mRNA CTD PMID:28939011 NCBI chr 5:154,294,841...154,308,582
Ensembl chr 5:154,294,806...154,308,640
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase decreases expression ISO dinophysistoxin 1 results in decreased expression of HMGCR mRNA CTD PMID:28939011 NCBI chr 2:27,480,224...27,500,654
Ensembl chr 2:27,480,226...27,500,654
JBrowse link
G Hspa2 heat shock protein family A (Hsp70) member 2 increases expression ISO dinophysistoxin 1 results in increased expression of HSPA2 mRNA CTD PMID:28939011 NCBI chr 6:99,433,575...99,436,288
Ensembl chr 6:99,433,550...99,436,289
JBrowse link
G Htra2 HtrA serine peptidase 2 increases expression ISO dinophysistoxin 1 results in increased expression of HTRA2 mRNA CTD PMID:28939011 NCBI chr 4:113,883,671...113,886,833
Ensembl chr 4:113,883,670...113,886,994
JBrowse link
G Ier3 immediate early response 3 increases expression ISO dinophysistoxin 1 results in increased expression of IER3 mRNA CTD PMID:28939011 NCBI chr20:3,438,798...3,440,002
Ensembl chr20:3,438,798...3,440,769
JBrowse link
G Iqcd IQ motif containing D increases expression ISO dinophysistoxin 1 results in increased expression of IQCD mRNA CTD PMID:28939011 NCBI chr12:41,490,451...41,507,416
Ensembl chr12:41,490,801...41,497,610
JBrowse link
G Irs2 insulin receptor substrate 2 increases expression ISO dinophysistoxin 1 results in increased expression of IRS2 mRNA CTD PMID:28939011 NCBI chr16:83,824,515...83,848,569
Ensembl chr16:83,824,430...83,848,684
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit increases expression ISO dinophysistoxin 1 results in increased expression of JUN mRNA CTD PMID:28939011 NCBI chr 5:114,011,184...114,014,277
Ensembl chr 5:114,011,189...114,014,277
JBrowse link
G Kcnj16 potassium inwardly-rectifying channel, subfamily J, member 16 decreases expression ISO dinophysistoxin 1 results in decreased expression of KCNJ16 mRNA CTD PMID:28939011 NCBI chr10:99,330,894...99,391,551
Ensembl chr10:99,388,130...99,389,898
JBrowse link
G Klf4 Kruppel like factor 4 increases expression ISO dinophysistoxin 1 results in increased expression of KLF4 mRNA CTD PMID:28939011 NCBI chr 5:72,283,311...72,287,669
Ensembl chr 5:72,283,313...72,287,669
JBrowse link
G Lama1 laminin subunit alpha 1 decreases expression ISO dinophysistoxin 1 results in decreased expression of LAMA1 mRNA CTD PMID:28939011 NCBI chr 9:115,916,907...116,042,123
Ensembl chr 9:115,916,907...116,042,123
JBrowse link
G Ldlr low density lipoprotein receptor increases expression ISO dinophysistoxin 1 results in increased expression of LDLR mRNA CTD PMID:28939011 NCBI chr 8:22,750,425...22,773,305
Ensembl chr 8:22,750,336...22,774,903
JBrowse link
G Lfng LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase increases expression ISO dinophysistoxin 1 results in increased expression of LFNG mRNA CTD PMID:28939011 NCBI chr12:16,117,767...16,126,211
Ensembl chr12:16,118,634...16,126,953
JBrowse link
G Lgsn lengsin, lens protein with glutamine synthetase domain decreases expression ISO dinophysistoxin 1 results in decreased expression of LGSN mRNA CTD PMID:28939011 NCBI chr 9:37,458,603...37,490,117
Ensembl chr 9:37,462,693...37,490,108
JBrowse link
G LOC103690190 histone H2A type 1-E decreases expression ISO dinophysistoxin 1 results in decreased expression of H2AC6 mRNA CTD PMID:28939011 NCBI chr17:44,747,686...44,748,229
Ensembl chr17:44,747,796...44,748,188
Ensembl chr17:44,747,796...44,748,188
JBrowse link
G Lyrm9 LYR motif containing 9 decreases expression ISO dinophysistoxin 1 results in decreased expression of LYRM9 mRNA CTD PMID:28939011 NCBI chr10:66,099,478...66,113,559
Ensembl chr10:66,099,531...66,113,559
JBrowse link
G Mab21l4 mab-21 like 4 decreases expression ISO dinophysistoxin 1 results in decreased expression of MAB21L4 mRNA CTD PMID:28939011 NCBI chr 9:100,296,780...100,307,415
Ensembl chr 9:100,296,781...100,306,829
JBrowse link
G Mafb MAF bZIP transcription factor B increases expression ISO dinophysistoxin 1 results in increased expression of MAFB mRNA CTD PMID:21853993, PMID:28939011 NCBI chr 3:156,338,993...156,340,913
Ensembl chr 3:156,339,004...156,340,913
JBrowse link
G Manf mesencephalic astrocyte-derived neurotrophic factor increases expression ISO dinophysistoxin 1 results in increased expression of MANF mRNA CTD PMID:28939011 NCBI chr 8:115,623,175...115,626,408
Ensembl chr 8:115,623,178...1