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G |
Ace |
angiotensin I converting enzyme |
decreases activity |
ISO |
nicotianamine results in decreased activity of ACE protein |
CTD |
PMID:26106051 |
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NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131
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G |
Ace2 |
angiotensin I converting enzyme 2 |
decreases activity |
ISO |
nicotianamine results in decreased activity of ACE2 protein |
CTD |
PMID:26106051 |
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NCBI chr X:30,293,597...30,340,961
Ensembl chr X:30,293,589...30,340,977
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G |
Bax |
BCL2 associated X, apoptosis regulator |
increases expression |
ISO |
alborixin results in increased expression of BAX protein |
CTD |
PMID:27378626 |
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NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
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G |
Bcl2 |
BCL2, apoptosis regulator |
decreases expression |
ISO |
alborixin results in decreased expression of BCL2 protein |
CTD |
PMID:27378626 |
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NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
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G |
Casp3 |
caspase 3 |
increases cleavage |
ISO |
alborixin results in increased cleavage of CASP3 protein |
CTD |
PMID:27378626 |
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NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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G |
Casp8 |
caspase 8 |
increases activity |
ISO |
alborixin results in increased activity of CASP8 protein |
CTD |
PMID:27378626 |
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NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
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G |
Casp9 |
caspase 9 |
increases activity |
ISO |
alborixin results in increased activity of CASP9 protein |
CTD |
PMID:27378626 |
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NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
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G |
Parp1 |
poly (ADP-ribose) polymerase 1 |
increases cleavage |
ISO |
alborixin results in increased cleavage of PARP1 protein |
CTD |
PMID:27378626 |
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NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
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G |
Agt |
angiotensinogen |
multiple interactions |
EXP |
bafilomycin A1 inhibits the reaction [AGT protein affects the localization of Calcium] |
CTD |
PMID:21613610 |
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NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977
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G |
Aim2 |
absent in melanoma 2 |
multiple interactions |
ISO |
[bafilomycin A1 co-treated with [sodium arsenite results in increased abundance of Arsenic]] results in increased expression of AIM2 protein |
CTD |
PMID:32645460 |
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NCBI chr13:85,865,206...85,906,996
Ensembl chr13:85,866,284...85,906,975
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G |
Akt1s1 |
AKT1 substrate 1 |
multiple interactions |
EXP |
bafilomycin A1 inhibits the reaction [EGF protein results in increased phosphorylation of AKT1S1 protein] |
CTD |
PMID:22689575 |
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NCBI chr 1:95,333,186...95,339,678
Ensembl chr 1:95,332,898...95,339,677
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G |
Alb |
albumin |
decreases uptake |
ISO |
bafilomycin A1 results in decreased uptake of ALB protein |
CTD |
PMID:16313995 |
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NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
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G |
Apaf1 |
apoptotic peptidase activating factor 1 |
increases expression |
ISO |
bafilomycin A1 results in increased expression of APAF1 protein |
CTD |
PMID:28483490 |
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NCBI chr 7:25,494,143...25,579,540
Ensembl chr 7:25,494,609...25,579,540
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G |
Appl1 |
adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 |
multiple interactions |
ISO |
bafilomycin A1 promotes the reaction [Lipopolysaccharides results in increased degradation of APPL1 protein]; bafilomycin A1 promotes the reaction [Poly I-C results in increased degradation of APPL1 protein] |
CTD |
PMID:25780039 |
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NCBI chr16:2,118,503...2,166,741
Ensembl chr16:2,121,255...2,166,692
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G |
Asic1 |
acid sensing ion channel subunit 1 |
multiple interactions |
ISO |
bafilomycin A1 inhibits the reaction [Freund's Adjuvant results in increased expression of ASIC1 mRNA] |
CTD |
PMID:16769263 |
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NCBI chr 7:130,798,317...130,828,535
Ensembl chr 7:130,799,917...130,828,541
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G |
Atg5 |
autophagy related 5 |
multiple interactions |
ISO |
ATG5 protein affects the reaction [bafilomycin A1 promotes the reaction [gossypol acetic acid results in increased expression of MAP1LC3B protein modified form]] [bafilomycin A1 co-treated with Swainsonine] results in increased expression of ATG5 mRNA; [bafilomycin A1 co-treated with Swainsonine] results in increased lipidation of ATG5 protein |
CTD |
PMID:29938581 PMID:36402259 |
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NCBI chr20:47,798,222...47,889,216
Ensembl chr20:47,798,290...47,889,209
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G |
Bax |
BCL2 associated X, apoptosis regulator |
multiple interactions |
ISO |
bafilomycin A1 inhibits the reaction [Hydroxychloroquine results in increased activity of BAX protein] |
CTD |
PMID:12813466 |
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NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
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G |
Bcl2 |
BCL2, apoptosis regulator |
decreases expression multiple interactions |
ISO EXP |
bafilomycin A1 results in decreased expression of BCL2 mRNA bafilomycin A1 promotes the reaction [Methamphetamine results in decreased expression of BCL2 protein] |
CTD |
PMID:31310755 PMID:34374793 |
|
NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
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G |
Becn1 |
beclin 1 |
multiple interactions increases expression |
ISO EXP |
bafilomycin A1 inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of BECN1 protein] [Swainsonine co-treated with bafilomycin A1] results in increased expression of BECN1 protein; bafilomycin A1 promotes the reaction [[lead acetate results in increased abundance of Lead] which results in increased expression of BECN1 protein] bafilomycin A1 results in increased expression of BECN1 protein |
CTD |
PMID:32645460 PMID:33186601 PMID:33242459 |
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NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742
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G |
Bglap |
bone gamma-carboxyglutamate protein |
multiple interactions |
ISO |
bafilomycin A1 inhibits the reaction [[Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid] results in increased expression of BGLAP mRNA] |
CTD |
PMID:23111315 |
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NCBI chr 2:173,838,518...173,839,495
Ensembl chr 2:173,838,518...173,839,495
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G |
Bid |
BH3 interacting domain death agonist |
multiple interactions increases cleavage increases expression |
EXP ISO |
bafilomycin A1 inhibits the reaction [manganese chloride results in increased expression of BID protein modified form]; bafilomycin A1 inhibits the reaction [manganese chloride results in increased expression of BID protein] vistusertib affects the reaction [bafilomycin A1 results in increased cleavage of BID protein] bafilomycin A1 results in increased expression of BID protein modified form |
CTD |
PMID:26853465 PMID:28378122 |
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NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720
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G |
Bnip3 |
BCL2 interacting protein 3 |
increases expression multiple interactions |
ISO |
bafilomycin A1 results in increased expression of BNIP3 mRNA; bafilomycin A1 results in increased expression of BNIP3 protein BNIP3 mutant form promotes the reaction [bafilomycin A1 results in increased cleavage of PARP1 protein]; capivasertib affects the reaction [bafilomycin A1 results in increased expression of BNIP3 protein]; Erlotinib Hydrochloride inhibits the reaction [bafilomycin A1 results in increased expression of BNIP3 protein]; Gefitinib inhibits the reaction [bafilomycin A1 results in increased expression of BNIP3 protein]; HIF1A mutant form inhibits the reaction [bafilomycin A1 results in increased expression of BNIP3 mRNA]; Lapatinib inhibits the reaction [bafilomycin A1 results in increased expression of BNIP3 mRNA]; vistusertib inhibits the reaction [bafilomycin A1 results in increased expression of BNIP3 protein] |
CTD |
PMID:25981168 PMID:26853465 |
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NCBI chr 1:193,708,164...193,725,348
Ensembl chr 1:193,708,167...193,725,359
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G |
C1qtnf9 |
C1q and TNF related 9 |
multiple interactions |
EXP |
bafilomycin A1 promotes the reaction [C1QTNF9 protein results in increased expression of MAP1LC3B protein modified form] |
CTD |
PMID:32278738 |
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NCBI chr15:34,907,791...34,922,985
Ensembl chr15:34,911,286...34,922,980
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G |
Casp3 |
caspase 3 |
decreases activity increases cleavage multiple interactions increases activity |
ISO EXP |
bafilomycin A1 results in decreased activity of CASP3 protein bafilomycin A1 results in increased cleavage of CASP3 protein bafilomycin A1 inhibits the reaction [Cadmium results in increased cleavage of CASP3 protein] bafilomycin A1 results in increased activity of CASP3 protein [Swainsonine co-treated with bafilomycin A1] results in increased cleavage of CASP3 protein; bafilomycin A1 inhibits the reaction [manganese chloride results in increased cleavage of CASP3 protein]; bafilomycin A1 promotes the reaction [Hydrogen Peroxide results in increased expression of CASP3 protein modified form]; bafilomycin A1 promotes the reaction [Methamphetamine results in increased cleavage of CASP3 protein] [bafilomycin A1 co-treated with Cannabidiol] results in increased cleavage of CASP3 protein; [bafilomycin A1 co-treated with cobaltous chloride co-treated with TP53 gene mutant form] results in increased activity of CASP3 protein; [bafilomycin A1 co-treated with methanandamide] results in increased cleavage of CASP3 protein; [Cannabidiol co-treated with bafilomycin A1] results in increased cleavage of CASP3 protein; bafilomycin A1 inhibits the reaction [Soot analog results in increased expression of CASP3 protein]; bafilomycin A1 inhibits the reaction [tetrandrine results in increased cleavage of CASP3 protein]; bafilomycin A1 promotes the reaction [Atorvastatin results in increased cleavage of CASP3 protein]; bafilomycin A1 promotes the reaction [brazilin results in increased activity of CASP3 protein]; bafilomycin A1 promotes the reaction [fosbretabulin results in increased cleavage of CASP3 protein]; tin protoporphyrin IX inhibits the reaction [[bafilomycin A1 co-treated with Cannabidiol] results in increased cleavage of CASP3 protein]; tin protoporphyrin IX inhibits the reaction [[bafilomycin A1 co-treated with methanandamide] results in increased cleavage of CASP3 protein]; vistusertib affects the reaction [bafilomycin A1 results in increased cleavage of CASP3 protein] |
CTD |
PMID:20876807 PMID:23380477 PMID:24321340 PMID:24889822 PMID:25266202 PMID:25981168 PMID:26853465 PMID:28063998 PMID:28378122 PMID:29111403 PMID:30240709 PMID:32708634 PMID:33076330 PMID:33186601 PMID:34374793 More...
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NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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G |
Casp4 |
caspase 4 |
increases activity |
ISO |
bafilomycin A1 results in increased activity of CASP4 protein |
CTD |
PMID:20371669 |
|
NCBI chr 8:2,599,017...2,635,097
Ensembl chr 8:2,598,876...2,635,092
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G |
Casp7 |
caspase 7 |
increases activity decreases activity |
ISO |
bafilomycin A1 results in increased activity of CASP7 protein bafilomycin A1 results in decreased activity of CASP7 protein |
CTD |
PMID:20371669 PMID:25981168 |
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NCBI chr 1:255,437,195...255,476,737
Ensembl chr 1:255,437,172...255,476,729
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G |
Casp8 |
caspase 8 |
multiple interactions |
EXP ISO |
bafilomycin A1 inhibits the reaction [manganese chloride results in increased cleavage of CASP8 protein] bafilomycin A1 inhibits the reaction [Cadmium results in increased cleavage of CASP8 protein] |
CTD |
PMID:28378122 PMID:29111403 |
|
NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
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G |
Casp9 |
caspase 9 |
multiple interactions |
EXP ISO |
bafilomycin A1 inhibits the reaction [manganese chloride results in increased cleavage of CASP9 protein] bafilomycin A1 inhibits the reaction [Soot analog results in increased expression of CASP9 protein] |
CTD |
PMID:28378122 PMID:30240709 |
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NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
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G |
Ccnd1 |
cyclin D1 |
multiple interactions |
ISO |
bafilomycin A1 inhibits the reaction [Dexamethasone results in decreased expression of CCND1 protein] |
CTD |
PMID:33359579 |
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NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
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G |
Cdc25c |
cell division cycle 25C |
multiple interactions |
ISO |
bafilomycin A1 inhibits the reaction [xanthatin results in decreased stability of CDC25C protein] |
CTD |
PMID:29074359 |
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NCBI chr18:26,335,156...26,356,199
Ensembl chr18:26,335,834...26,356,185
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G |
Cdh1 |
cadherin 1 |
multiple interactions |
ISO |
bafilomycin A1 inhibits the reaction [Capsaicin results in increased expression of CDH1 protein] |
CTD |
PMID:36044967 |
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NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775
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G |
Cdh2 |
cadherin 2 |
multiple interactions |
ISO |
bafilomycin A1 inhibits the reaction [Capsaicin results in decreased expression of CDH2 protein] |
CTD |
PMID:36044967 |
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NCBI chr18:7,776,704...7,990,934
Ensembl chr18:7,776,704...7,990,167
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G |
Ctsb |
cathepsin B |
multiple interactions |
ISO |
bafilomycin A1 inhibits the reaction [[cobaltous chloride co-treated with TP53 gene mutant form] results in increased activity of CTSB protein]; bafilomycin A1 inhibits the reaction [Hydroxychloroquine affects the localization of CTSB protein] |
CTD |
PMID:12813466 PMID:23380477 |
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NCBI chr15:37,389,636...37,410,508
Ensembl chr15:37,389,629...37,410,500
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G |
Ctsd |
cathepsin D |
decreases cleavage |
ISO |
bafilomycin A1 results in decreased cleavage of CTSD protein |
CTD |
PMID:36070022 |
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NCBI chr 1:197,527,467...197,539,343
Ensembl chr 1:197,527,467...197,539,488
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G |
Ctsl |
cathepsin L |
decreases cleavage |
ISO |
bafilomycin A1 results in decreased cleavage of CTSL protein |
CTD |
PMID:36070022 |
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NCBI chr17:764,370...770,533
Ensembl chr17:764,309...770,548
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G |
Cxcl10 |
C-X-C motif chemokine ligand 10 |
multiple interactions |
ISO |
bafilomycin A1 inhibits the reaction [CpG ODN 2216 results in increased expression of CXCL10 protein]; bafilomycin A1 inhibits the reaction [gardiquimod results in increased expression of CXCL10 protein]; bafilomycin A1 inhibits the reaction [Poly I-C results in increased expression of CXCL10 protein] |
CTD |
PMID:26682054 |
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NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975
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G |
Ddit4 |
DNA-damage-inducible transcript 4 |
increases expression multiple interactions |
EXP |
bafilomycin A1 results in increased expression of DDIT4 protein [EGF protein co-treated with bafilomycin A1] results in increased expression of DDIT4 protein |
CTD |
PMID:22689575 |
|
NCBI chr20:27,891,989...27,894,088
Ensembl chr20:27,891,998...27,894,105
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G |
Egf |
epidermal growth factor |
multiple interactions |
EXP |
[bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Arginine; [bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Asparagine; [bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Isoleucine; [bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Leucine; [bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Lysine; [bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Methionine; [bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Ornithine; [bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Phenylalanine; [bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Tyrosine; [bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Valine; [bafilomycin A1 co-treated with EGF protein] results in increased abundance of Aspartic Acid; [bafilomycin A1 co-treated with EGF protein] results in increased abundance of Taurine; [EGF protein co-treated with bafilomycin A1] results in increased expression of DDIT4 protein; bafilomycin A1 inhibits the reaction [EGF protein results in increased activity of and results in increased phosphorylation of RPS6KB1 protein]; bafilomycin A1 inhibits the reaction [EGF protein results in increased phosphorylation of AKT1S1 protein]; bafilomycin A1 inhibits the reaction [EGF protein results in increased phosphorylation of EIF4EBP1 protein]; Cycloheximide inhibits the reaction [[bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Arginine]; Cycloheximide inhibits the reaction [[bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Asparagine]; Cycloheximide inhibits the reaction [[bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Isoleucine]; Cycloheximide inhibits the reaction [[bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Leucine]; Cycloheximide inhibits the reaction [[bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Lysine]; Cycloheximide inhibits the reaction [[bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Methionine]; Cycloheximide inhibits the reaction [[bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Ornithine]; Cycloheximide inhibits the reaction [[bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Phenylalanine]; Cycloheximide inhibits the reaction [[bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Tyrosine]; Cycloheximide inhibits the reaction [[bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Valine] |
CTD |
PMID:22689575 |
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NCBI chr 2:218,219,408...218,302,370
Ensembl chr 2:218,219,415...218,302,064
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G |
Egfr |
epidermal growth factor receptor |
multiple interactions |
ISO |
bafilomycin A1 inhibits the reaction [Arsenic Trioxide results in decreased expression of EGFR protein] |
CTD |
PMID:30237564 |
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NCBI chr14:91,176,931...91,349,722
Ensembl chr14:91,177,067...91,344,382
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G |
Eif4ebp1 |
eukaryotic translation initiation factor 4E binding protein 1 |
multiple interactions |
EXP |
bafilomycin A1 inhibits the reaction [EGF protein results in increased phosphorylation of EIF4EBP1 protein]; bafilomycin A1 inhibits the reaction [INS protein results in increased phosphorylation of EIF4EBP1 protein] |
CTD |
PMID:22689575 |
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NCBI chr16:64,792,595...64,805,984
Ensembl chr16:64,790,226...64,805,984
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G |
Epor |
erythropoietin receptor |
multiple interactions |
ISO |
bafilomycin A1 inhibits the reaction [Aristolochic Acids results in increased degradation of and results in decreased expression of EPOR protein] |
CTD |
PMID:26136230 |
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NCBI chr 8:20,489,678...20,494,257
Ensembl chr 8:20,489,678...20,494,257
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G |
Faslg |
Fas ligand |
multiple interactions |
ISO EXP |
bafilomycin A1 inhibits the reaction [FASL protein affects the localization of Calcium] bafilomycin A1 inhibits the reaction [manganese chloride results in increased expression of FASLG protein] |
CTD |
PMID:20200208 PMID:28378122 |
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NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215
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G |
Fmc1 |
formation of mitochondrial complex V assembly factor 1 |
multiple interactions |
ISO |
bafilomycin A1 inhibits the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone results in decreased expression of FMC1 protein] |
CTD |
PMID:29371327 |
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NCBI chr 4:67,274,104...67,282,140
Ensembl chr 4:67,274,104...67,282,140
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G |
Foxo1 |
forkhead box O1 |
multiple interactions |
EXP |
bafilomycin A1 inhibits the reaction [resveratrol inhibits the reaction [Hydrogen Peroxide results in increased acetylation of FOXO1 protein]] |
CTD |
PMID:24889822 |
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NCBI chr 2:136,312,168...136,390,603
Ensembl chr 2:136,312,168...136,387,790
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G |
Gja1 |
gap junction protein, alpha 1 |
increases expression |
ISO |
bafilomycin A1 results in increased expression of GJA1 protein |
CTD |
PMID:35750204 |
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NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582
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G |
Hif1a |
hypoxia inducible factor 1 subunit alpha |
increases expression multiple interactions |
ISO |
bafilomycin A1 results in increased expression of HIF1A protein HIF1A mutant form inhibits the reaction [bafilomycin A1 results in increased expression of BNIP3 mRNA]; HIF1A mutant form promotes the reaction [bafilomycin A1 results in increased cleavage of PARP1 protein]; lapatinib inhibits the reaction [bafilomycin A1 results in increased expression of HIF1A protein] |
CTD |
PMID:25981168 |
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NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
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G |
Hmox1 |
heme oxygenase 1 |
decreases expression multiple interactions |
ISO |
bafilomycin A1 results in decreased expression of HMOX1 protein [bafilomycin A1 co-treated with methanandamide] results in increased expression of HMOX1 protein; [bafilomycin A1 co-treated with tin protoporphyrin IX] promotes the reaction [Cannabidiol results in increased expression of HMOX1 protein]; bafilomycin A1 inhibits the reaction [4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole results in increased expression of HMOX1 protein] |
CTD |
PMID:29796178 PMID:33076330 |
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NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
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G |
Ifng |
interferon gamma |
decreases expression |
ISO |
bafilomycin A1 results in decreased expression of IFNG mRNA |
CTD |
PMID:16932910 |
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NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
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G |
Il1b |
interleukin 1 beta |
decreases expression multiple interactions |
ISO |
bafilomycin A1 results in decreased expression of IL1B mRNA [bafilomycin A1 co-treated with [sodium arsenite results in increased abundance of Arsenic]] results in increased expression of IL1B protein; bafilomycin A1 inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with aluminum sulfate] results in increased secretion of IL1B protein] |
CTD |
PMID:16932910 PMID:24158569 PMID:32645460 |
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NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
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G |
Il6 |
interleukin 6 |
increases expression |
ISO |
bafilomycin A1 results in increased expression of IL6 mRNA |
CTD |
PMID:16932910 |
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NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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G |
Ins1 |
insulin 1 |
multiple interactions |
ISO |
bafilomycin A1 promotes the reaction [Palmitic Acid inhibits the reaction [INS1 protein results in increased uptake of 2-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose]] |
CTD |
PMID:32283200 |
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NCBI chr 1:251,244,973...251,245,540
Ensembl chr 1:251,244,973...251,245,536
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G |
Ins2 |
insulin 2 |
multiple interactions |
EXP |
bafilomycin A1 inhibits the reaction [INS protein results in increased phosphorylation of EIF4EBP1 protein]; bafilomycin A1 inhibits the reaction [INS protein results in increased phosphorylation of RPS6KB1 protein] |
CTD |
PMID:22689575 |
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NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775
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G |
Keap1 |
Kelch-like ECH-associated protein 1 |
multiple interactions |
ISO |
bafilomycin A1 promotes the reaction [pachastrissamine analog promotes the reaction [KEAP1 protein binds to SQSTM1 protein]] |
CTD |
PMID:35123989 |
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NCBI chr 8:19,768,375...19,777,862
Ensembl chr 8:19,768,375...19,777,862
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G |
Lamp1 |
lysosomal-associated membrane protein 1 |
multiple interactions increases expression |
ISO |
[bafilomycin A1 co-treated with Swainsonine] results in increased expression of LAMP1 mRNA; [bafilomycin A1 co-treated with Swainsonine] results in increased expression of LAMP1 protein bafilomycin A1 results in increased expression of LAMP1 protein |
CTD |
PMID:36402259 |
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NCBI chr16:76,355,982...76,380,700
Ensembl chr16:76,355,984...76,381,883
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G |
Lrrk2 |
leucine-rich repeat kinase 2 |
increases response to substance |
ISO |
LRRK2 gene mutant form results in increased susceptibility to bafilomycin A1 |
CTD |
PMID:25017139 |
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NCBI chr 7:122,826,712...122,987,711
Ensembl chr 7:122,826,696...122,987,703
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G |
Man2a1 |
mannosidase, alpha, class 2A, member 1 |
multiple interactions |
ISO |
bafilomycin A1 inhibits the reaction [Swainsonine results in decreased expression of MAN2A1 mRNA] |
CTD |
PMID:36402259 |
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NCBI chr 9:104,252,001...104,408,349
Ensembl chr 9:104,252,001...104,408,349
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G |
Man2b1 |
mannosidase, alpha, class 2B, member 1 |
multiple interactions |
ISO |
bafilomycin A1 inhibits the reaction [Swainsonine results in decreased expression of MAN2B1 mRNA] |
CTD |
PMID:36402259 |
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NCBI chr19:23,055,092...23,074,398
Ensembl chr19:23,055,097...23,074,389
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G |
Map1lc3a |
microtubule-associated protein 1 light chain 3 alpha |
multiple interactions increases expression |
ISO |
bafilomycin A1 promotes the reaction [Uranium results in increased expression of MAP1LC3A protein] bafilomycin A1 results in increased expression of MAP1LC3A protein modified form |
CTD |
PMID:30871063 PMID:31120128 |
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NCBI chr 3:143,783,024...143,784,670
Ensembl chr 3:143,783,024...143,784,670
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G |
Map1lc3b |
microtubule-associated protein 1 light chain 3 beta |
multiple interactions increases lipidation increases expression increases cleavage decreases degradation |
ISO EXP |
[bafilomycin A1 co-treated with Miconazole] results in increased expression of MAP1LC3B protein; [di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone co-treated with bafilomycin A1] results in increased expression of MAP1LC3B mRNA; [TNF protein co-treated with bafilomycin A1] results in increased expression of MAP1LC3B protein alternative form; Acetylcysteine inhibits the reaction [di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone promotes the reaction [bafilomycin A1 results in increased expression of MAP1LC3B protein]]; ATG5 protein affects the reaction [bafilomycin A1 promotes the reaction [gossypol acetic acid results in increased expression of MAP1LC3B protein modified form]]; bafilomycin A1 affects the reaction [Ammonium Chloride results in increased metabolism of MAP1LC3B protein]; bafilomycin A1 affects the reaction [AZD4547 affects the expression of MAP1LC3B protein modified form]; bafilomycin A1 affects the reaction [AZD8186 affects the expression of MAP1LC3B protein modified form]; bafilomycin A1 inhibits the reaction [Chloroquine results in increased lipidation of MAP1LC3B protein]; bafilomycin A1 promotes the reaction [[alpha-Chlorohydrin co-treated with Diosgenin] results in increased lipidation of MAP1LC3B protein]; bafilomycin A1 promotes the reaction [capivasertib results in increased expression of MAP1LC3B protein modified form]; bafilomycin A1 promotes the reaction [Curcumin results in increased lipidation of MAP1LC3B protein]; bafilomycin A1 promotes the reaction [ginsenoside Rg2 results in increased expression of MAP1LC3B protein modified form]; bafilomycin A1 promotes the reaction [gossypol acetic acid results in increased expression of MAP1LC3B protein modified form]; bafilomycin A1 promotes the reaction [metarrestin results in increased expression of MAP1LC3B protein modified form]; bafilomycin A1 promotes the reaction [Miconazole results in increased lipidation of MAP1LC3B protein]; bafilomycin A1 promotes the reaction [Particulate Matter results in increased expression of MAP1LC3B protein]; bafilomycin A1 promotes the reaction [Resveratrol results in increased expression of MAP1LC3B protein alternative form]; bafilomycin A1 promotes the reaction [Sevoflurane results in increased lipidation of MAP1LC3B protein]; bafilomycin A1 promotes the reaction [vistusertib results in increased expression of MAP1LC3B protein modified form]; bafilomycin A1 results in increased expression of and results in increased lipidation of MAP1LC3B protein; di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone promotes the reaction [bafilomycin A1 results in increased expression of MAP1LC3B protein]; Resveratrol promotes the reaction [[TNF protein co-treated with bafilomycin A1] results in increased expression of MAP1LC3B protein alternative form] bafilomycin A1 results in increased lipidation of MAP1LC3B protein [Doxorubicin co-treated with bafilomycin A1] results in increased expression of MAP1LC3B protein; [Glycyrrhizic Acid co-treated with bafilomycin A1] results in increased lipidation of MAP1LC3B protein; bafilomycin A1 promotes the reaction [C1QTNF9 protein results in increased expression of MAP1LC3B protein modified form] bafilomycin A1 results in increased expression of MAP1LC3B protein modified form [bafilomycin A1 co-treated with Swainsonine] results in increased expression of MAP1LC3B mRNA; [bafilomycin A1 co-treated with Swainsonine] results in increased lipidation of MAP1LC3B protein; bafilomycin A1 promotes the reaction [Triiodothyronine results in increased lipidation of MAP1LC3B protein]; Triiodothyronine promotes the reaction [bafilomycin A1 results in increased lipidation of MAP1LC3B protein] bafilomycin A1 results in increased cleavage of MAP1LC3B protein bafilomycin A1 results in decreased degradation of MAP1LC3B protein modified form bafilomycin A1 results in increased expression of MAP1LC3B protein; bafilomycin A1 results in increased expression of MAP1LC3B protein alternative form; bafilomycin A1 results in increased expression of MAP1LC3B protein modified form |
CTD |
PMID:23880069 PMID:24145604 PMID:25301941 PMID:26459185 PMID:26853465 PMID:27305347 PMID:29248574 PMID:29524503 PMID:29908302 PMID:29938581 PMID:30209975 PMID:31310755 PMID:32278738 PMID:32525084 PMID:32981224 PMID:34580807 PMID:34634291 PMID:35149085 PMID:35472370 PMID:35872226 PMID:36070022 PMID:36402259 More...
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NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690
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G |
Mapk1 |
mitogen activated protein kinase 1 |
multiple interactions increases expression |
ISO |
bafilomycin A1 inhibits the reaction [Capsaicin results in increased activity of MAPK1 protein]; bafilomycin A1 inhibits the reaction [Iron Compounds results in increased expression of MAPK1 protein modified form]; bafilomycin A1 promotes the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased phosphorylation of MAPK1 protein] bafilomycin A1 results in increased expression of MAPK1 protein modified form |
CTD |
PMID:20371669 PMID:28483490 PMID:32645460 |
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NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
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G |
Mapk3 |
mitogen activated protein kinase 3 |
multiple interactions increases expression |
ISO |
bafilomycin A1 inhibits the reaction [Capsaicin results in increased activity of MAPK3 protein]; bafilomycin A1 inhibits the reaction [Iron Compounds results in increased expression of MAPK3 protein modified form]; bafilomycin A1 promotes the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased phosphorylation of MAPK3 protein] bafilomycin A1 results in increased expression of MAPK3 protein modified form |
CTD |
PMID:20371669 PMID:28483490 PMID:32645460 |
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NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
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G |
Mapk8 |
mitogen-activated protein kinase 8 |
increases phosphorylation |
ISO |
bafilomycin A1 results in increased phosphorylation of MAPK8 protein |
CTD |
PMID:31310755 |
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NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
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G |
Mtor |
mechanistic target of rapamycin kinase |
decreases phosphorylation |
ISO |
bafilomycin A1 results in decreased phosphorylation of MTOR protein |
CTD |
PMID:31310755 |
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NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
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G |
Mttp |
microsomal triglyceride transfer protein |
increases expression |
ISO |
bafilomycin A1 results in increased expression of MTTP protein |
CTD |
PMID:34516972 |
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NCBI chr 2:226,613,090...226,654,239
Ensembl chr 2:226,613,090...226,654,239
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G |
Ndrg1 |
N-myc downstream regulated 1 |
multiple interactions |
ISO |
NDRG1 protein results in decreased susceptibility to [di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone co-treated with bafilomycin A1] |
CTD |
PMID:24532803 |
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NCBI chr 7:98,684,487...98,725,869
Ensembl chr 7:98,684,487...98,725,880
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G |
Nfe2l2 |
NFE2 like bZIP transcription factor 2 |
multiple interactions increases expression |
ISO |
bafilomycin A1 promotes the reaction [[Particulate Matter co-treated with Vitamin D] results in increased expression of NFE2L2 protein]; bafilomycin A1 promotes the reaction [[Silicon Dioxide co-treated with Vitamin D] results in increased expression of NFE2L2 protein]; bafilomycin A1 promotes the reaction [Particulate Matter results in increased expression of NFE2L2 protein]; bafilomycin A1 promotes the reaction [Silicon Dioxide results in increased expression of NFE2L2 protein] bafilomycin A1 results in increased expression of NFE2L2 protein |
CTD |
PMID:30698894 |
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NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737
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G |
Nlrp3 |
NLR family, pyrin domain containing 3 |
multiple interactions increases expression |
ISO |
bafilomycin A1 inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of NLRP3 protein] bafilomycin A1 results in increased expression of NLRP3 protein |
CTD |
PMID:32645460 |
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NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811
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G |
Nr5a1 |
nuclear receptor subfamily 5, group A, member 1 |
decreases expression |
ISO |
bafilomycin A1 results in decreased expression of NR5A1 protein |
CTD |
PMID:29524503 |
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NCBI chr 3:22,464,786...22,486,328
Ensembl chr 3:22,465,502...22,486,328
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G |
Parp1 |
poly (ADP-ribose) polymerase 1 |
multiple interactions increases cleavage increases expression |
ISO EXP |
[Cysteine Proteinase Inhibitors results in decreased activity of USP8 protein] promotes the reaction [bafilomycin A1 results in increased cleavage of PARP1 protein]; bafilomycin A1 promotes the reaction [[Cysteine Proteinase Inhibitors results in decreased activity of USP8 protein] which results in increased cleavage of PARP1 protein]; bafilomycin A1 promotes the reaction [Atorvastatin results in increased cleavage of PARP1 protein]; bafilomycin A1 promotes the reaction [brazilin results in increased expression of PARP1 protein modified form]; bafilomycin A1 promotes the reaction [Flavanones results in increased cleavage of PARP1 protein]; bafilomycin A1 promotes the reaction [fosbretabulin results in increased cleavage of PARP1 protein]; BNIP3 mutant form promotes the reaction [bafilomycin A1 results in increased cleavage of PARP1 protein]; HIF1A mutant form promotes the reaction [bafilomycin A1 results in increased cleavage of PARP1 protein] bafilomycin A1 promotes the reaction [Methamphetamine results in increased cleavage of PARP1 protein] bafilomycin A1 inhibits the reaction [Cadmium results in increased cleavage of PARP1 protein] bafilomycin A1 results in increased expression of PARP1 protein modified form |
CTD |
PMID:20876807 PMID:21616090 PMID:24321340 PMID:25981168 PMID:28063998 PMID:29111403 PMID:31310755 PMID:34374793 PMID:35022897 More...
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NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
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G |
Pcna |
proliferating cell nuclear antigen |
multiple interactions |
ISO |
bafilomycin A1 inhibits the reaction [Dexamethasone results in decreased expression of PCNA mRNA] |
CTD |
PMID:33359579 |
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NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995
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G |
Rela |
RELA proto-oncogene, NF-kB subunit |
multiple interactions |
ISO |
bafilomycin A1 affects the localization of and results in increased activity of RELA protein |
CTD |
PMID:10339586 |
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NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
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G |
Rps6kb1 |
ribosomal protein S6 kinase B1 |
decreases phosphorylation multiple interactions |
ISO EXP |
bafilomycin A1 results in decreased phosphorylation of RPS6KB1 protein bafilomycin A1 inhibits the reaction [EGF protein results in increased activity of and results in increased phosphorylation of RPS6KB1 protein]; bafilomycin A1 inhibits the reaction [INS protein results in increased phosphorylation of RPS6KB1 protein] |
CTD |
PMID:22689575 PMID:31310755 |
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NCBI chr10:71,323,777...71,367,908
Ensembl chr10:71,323,777...71,367,908
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G |
Runx2 |
RUNX family transcription factor 2 |
multiple interactions |
ISO |
bafilomycin A1 inhibits the reaction [[Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid] results in increased expression of RUNX2 mRNA] |
CTD |
PMID:23111315 |
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NCBI chr 9:16,167,504...16,492,826
Ensembl chr 9:16,167,482...16,492,167
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G |
Sirt1 |
sirtuin 1 |
multiple interactions |
EXP |
bafilomycin A1 inhibits the reaction [resveratrol inhibits the reaction [Hydrogen Peroxide results in decreased expression of SIRT1 protein]] |
CTD |
PMID:24889822 |
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NCBI chr20:25,307,143...25,329,260
Ensembl chr20:25,306,917...25,329,260
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G |
Slc17a7 |
solute carrier family 17 member 7 |
multiple interactions |
EXP |
bafilomycin A1 inhibits the reaction [SLC17A7 protein results in increased uptake of Excitatory Amino Acid Agents]; bafilomycin A1 inhibits the reaction [SLC17A7 protein results in increased uptake of Zinc]; bafilomycin A1 inhibits the reaction [SLC30A3 protein promotes the reaction [SLC17A7 protein results in increased uptake of Zinc]] |
CTD |
PMID:15860731 |
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NCBI chr 1:95,649,709...95,661,591
Ensembl chr 1:95,649,745...95,661,588
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G |
Slc30a3 |
solute carrier family 30 member 3 |
multiple interactions |
EXP |
bafilomycin A1 inhibits the reaction [SLC30A3 protein promotes the reaction [SLC17A7 protein results in increased uptake of Zinc]] |
CTD |
PMID:15860731 |
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NCBI chr 6:25,264,310...25,284,720
Ensembl chr 6:25,275,528...25,284,720
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G |
Snai1 |
snail family transcriptional repressor 1 |
multiple interactions increases expression |
ISO |
bafilomycin A1 promotes the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of SNAI1 protein] bafilomycin A1 results in increased expression of SNAI1 protein |
CTD |
PMID:32645460 |
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NCBI chr 3:156,248,479...156,252,969
Ensembl chr 3:156,248,485...156,252,969
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G |
Snca |
synuclein alpha |
multiple interactions increases expression |
ISO |
[bafilomycin A1 co-treated with Rotenone] results in increased expression of SNCA protein bafilomycin A1 results in increased expression of SNCA protein |
CTD |
PMID:26031332 |
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NCBI chr 4:89,696,420...89,797,240
Ensembl chr 4:89,696,420...89,796,262
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G |
Sort1 |
sortilin 1 |
decreases expression |
ISO |
bafilomycin A1 results in decreased expression of SORT1 protein |
CTD |
PMID:25805502 |
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NCBI chr 2:195,924,033...196,002,354
Ensembl chr 2:195,924,099...196,002,354
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G |
Sqstm1 |
sequestosome 1 |
increases expression multiple interactions |
ISO EXP |
bafilomycin A1 results in increased expression of SQSTM1 protein bafilomycin A1 promotes the reaction [Hydrogen Peroxide results in increased expression of SQSTM1 protein] [Resveratrol co-treated with bafilomycin A1] results in increased expression of SQSTM1 protein; [Silicon Dioxide co-treated with bafilomycin A1] results in increased expression of SQSTM1 protein; [Silicon Dioxide co-treated with Vitamin D co-treated with bafilomycin A1] results in increased expression of SQSTM1 protein; [TNF protein co-treated with bafilomycin A1] results in increased expression of SQSTM1 protein; [Vitamin D co-treated with bafilomycin A1] results in increased expression of SQSTM1 protein; bafilomycin A1 inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of SQSTM1 protein]; bafilomycin A1 inhibits the reaction [dactolisib results in decreased expression of SQSTM1 protein]; bafilomycin A1 inhibits the reaction [Dexamethasone results in decreased expression of SQSTM1 protein]; bafilomycin A1 inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of SQSTM1 protein]]; bafilomycin A1 inhibits the reaction [Resveratrol results in increased degradation of SQSTM1 protein]; bafilomycin A1 inhibits the reaction [Sorafenib results in decreased expression of SQSTM1 protein]; bafilomycin A1 promotes the reaction [ginsenoside Rg2 results in decreased expression of SQSTM1 protein]; bafilomycin A1 promotes the reaction [metarrestin results in decreased expression of SQSTM1 protein]; bafilomycin A1 promotes the reaction [Miconazole results in increased expression of SQSTM1 protein]; bafilomycin A1 promotes the reaction [N-Methyl-3,4-methylenedioxyamphetamine results in increased expression of SQSTM1 protein]; bafilomycin A1 promotes the reaction [pachastrissamine analog promotes the reaction [KEAP1 protein binds to SQSTM1 protein]]; Fingolimod Hydrochloride affects the reaction [bafilomycin A1 results in increased expression of SQSTM1 protein]; sodium arsenite promotes the reaction [bafilomycin A1 results in increased expression of SQSTM1 protein] [bafilomycin A1 co-treated with Rotenone] results in increased expression of SQSTM1 protein; [bafilomycin A1 co-treated with Swainsonine] results in increased expression of SQSTM1 mRNA; [bafilomycin A1 co-treated with Swainsonine] results in increased lipidation of SQSTM1 protein; bafilomycin A1 inhibits the reaction [Resveratrol inhibits the reaction [Streptozocin results in increased expression of SQSTM1 protein]]; bafilomycin A1 inhibits the reaction [Sirolimus results in decreased expression of SQSTM1 protein]; decamethrin promotes the reaction [bafilomycin A1 results in increased expression of SQSTM1 protein]; Streptozocin promotes the reaction [bafilomycin A1 results in increased expression of SQSTM1 protein] |
CTD |
PMID:21778691 PMID:21858812 PMID:23151917 PMID:24145604 PMID:24238063 PMID:24889822 PMID:25939952 PMID:25943029 PMID:26031332 PMID:27305347 PMID:28125038 PMID:29248574 PMID:29524503 PMID:30698894 PMID:32186374 PMID:32645460 PMID:32981224 PMID:33359579 PMID:34405320 PMID:34520793 PMID:34580807 PMID:35123989 PMID:36070022 PMID:36402259 More...
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NCBI chr10:34,525,517...34,536,685
Ensembl chr10:34,525,519...34,536,673
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G |
Tbk1 |
TANK-binding kinase 1 |
multiple interactions |
ISO |
bafilomycin A1 promotes the reaction [Lipopolysaccharides results in increased phosphorylation of TBK1 protein]; bafilomycin A1 promotes the reaction [Poly I-C results in increased phosphorylation of TBK1 protein] |
CTD |
PMID:25780039 |
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NCBI chr 7:57,077,830...57,110,868
Ensembl chr 7:57,077,830...57,110,892
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G |
Tlr8 |
toll-like receptor 8 |
multiple interactions |
ISO |
bafilomycin A1 inhibits the reaction [resiquimod results in increased activity of TLR8 protein] |
CTD |
PMID:21398612 |
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NCBI chr X:27,091,780...27,116,092
Ensembl chr X:27,091,778...27,116,549
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G |
Tnf |
tumor necrosis factor |
increases expression multiple interactions |
ISO |
bafilomycin A1 results in increased expression of TNF mRNA [TNF protein co-treated with bafilomycin A1] results in increased expression of MAP1LC3B protein alternative form; [TNF protein co-treated with bafilomycin A1] results in increased expression of SQSTM1 protein; resveratrol promotes the reaction [[TNF protein co-treated with bafilomycin A1] results in increased expression of MAP1LC3B protein alternative form] |
CTD |
PMID:16932910 PMID:24145604 |
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NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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G |
Tomm20 |
translocase of outer mitochondrial membrane 20 |
increases expression multiple interactions |
ISO |
bafilomycin A1 results in increased expression of TOMM20 protein Triiodothyronine promotes the reaction [bafilomycin A1 results in increased expression of TOMM20 protein] |
CTD |
PMID:30209975 |
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NCBI chr19:54,925,197...54,935,188
Ensembl chr19:54,923,402...54,935,198
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G |
Tp53 |
tumor protein p53 |
multiple interactions |
ISO |
[bafilomycin A1 co-treated with cobaltous chloride co-treated with TP53 gene mutant form] results in increased activity of CASP3 protein; bafilomycin A1 inhibits the reaction [[cobaltous chloride co-treated with TP53 gene mutant form] results in increased activity of CTSB protein] |
CTD |
PMID:23380477 |
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NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
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G |
Ulk1 |
unc-51 like autophagy activating kinase 1 |
multiple interactions |
EXP |
bafilomycin A1 affects the reaction [N-(1,3-benzodioxol-5-ylmethyl)-2,6-dichlorobenzamide affects the reaction [Glucose affects the phosphorylation of ULK1 protein]] |
CTD |
PMID:29128638 |
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NCBI chr12:45,851,710...45,877,966
Ensembl chr12:45,851,710...45,877,966
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G |
Usp8 |
ubiquitin specific peptidase 8 |
multiple interactions |
ISO |
[Cysteine Proteinase Inhibitors results in decreased activity of USP8 protein] promotes the reaction [bafilomycin A1 results in increased cleavage of PARP1 protein]; bafilomycin A1 promotes the reaction [[Cysteine Proteinase Inhibitors results in decreased activity of USP8 protein] which results in increased cleavage of PARP1 protein] |
CTD |
PMID:35022897 |
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NCBI chr 3:113,962,136...114,009,683
Ensembl chr 3:113,962,164...114,009,666
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G |
Vdac1 |
voltage-dependent anion channel 1 |
multiple interactions increases expression |
ISO |
Triiodothyronine promotes the reaction [bafilomycin A1 results in increased expression of VDAC1 protein] |
CTD |
PMID:30209975 |
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NCBI chr10:36,532,306...36,559,642
Ensembl chr10:36,532,244...36,559,640
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G |
Vdr |
vitamin D receptor |
multiple interactions |
ISO |
[bafilomycin A1 co-treated with Vitamin D] results in increased expression of VDR protein; [Silicon Dioxide co-treated with Vitamin D co-treated with bafilomycin A1] results in increased expression of VDR protein |
CTD |
PMID:30698894 |
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NCBI chr 7:128,987,981...129,037,677
Ensembl chr 7:128,987,981...129,037,677
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G |
Vim |
vimentin |
multiple interactions increases expression |
ISO |
bafilomycin A1 promotes the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of VIM protein] bafilomycin A1 results in increased expression of VIM protein |
CTD |
PMID:32645460 |
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NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187
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G |
Aatf |
apoptosis antagonizing transcription factor |
decreases expression |
ISO |
beauvericin results in decreased expression of AATF mRNA |
CTD |
PMID:29203277 |
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NCBI chr10:69,299,029...69,392,207
Ensembl chr10:69,299,037...69,392,201
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G |
Abca1 |
ATP binding cassette subfamily A member 1 |
multiple interactions |
ISO |
[beauvericin co-treated with enniatins] results in decreased expression of ABCA1 mRNA |
CTD |
PMID:31100301 |
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NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170
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G |
Abcg1 |
ATP binding cassette subfamily G member 1 |
multiple interactions |
ISO |
[beauvericin co-treated with enniatins] results in decreased expression of ABCG1 mRNA |
CTD |
PMID:31100301 |
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NCBI chr20:9,126,687...9,182,948
Ensembl chr20:9,126,687...9,182,948
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G |
Acat2 |
acetyl-CoA acetyltransferase 2 |
multiple interactions |
ISO |
[beauvericin co-treated with enniatins] results in decreased expression of ACAT2 protein |
CTD |
PMID:32407736 |
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NCBI chr 1:47,695,833...47,713,879
Ensembl chr 1:47,695,788...47,752,821
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G |
Acin1 |
apoptotic chromatin condensation inducer 1 |
decreases expression |
ISO |
beauvericin results in decreased expression of ACIN1 mRNA |
CTD |
PMID:29203277 |
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NCBI chr15:28,102,112...28,147,001
Ensembl chr15:28,102,112...28,147,001
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G |
Acsl4 |
acyl-CoA synthetase long-chain family member 4 |
multiple interactions |
ISO |
[beauvericin co-treated with enniatins] results in decreased expression of ACSL4 protein |
CTD |
PMID:32407736 |
|
NCBI chr X:105,942,794...106,006,573
Ensembl chr X:105,942,799...106,006,427
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G |
Actb |
actin, beta |
decreases expression |
ISO |
beauvericin results in decreased expression of ACTB mRNA |
CTD |
PMID:29203277 |
|
NCBI chr12:11,663,112...11,666,697
Ensembl chr12:11,663,109...11,672,877
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G |
Aen |
apoptosis enhancing nuclease |
decreases expression |
ISO |
beauvericin results in decreased expression of AEN mRNA |
CTD |
PMID:29203277 |
|
NCBI chr 1:132,815,094...132,824,522
Ensembl chr 1:132,815,142...132,824,523
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G |
Aifm1 |
apoptosis inducing factor, mitochondria associated 1 |
decreases expression |
ISO |
beauvericin results in decreased expression of AIFM1 mRNA |
CTD |
PMID:29203277 |
|
NCBI chr X:127,650,223...127,689,356
Ensembl chr X:127,650,226...127,689,256
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G |
Ak4 |
adenylate kinase 4 |
multiple interactions |
ISO |
[beauvericin co-treated with enniatins] results in decreased expression of AK4 mRNA |
CTD |
PMID:31100301 |
|
NCBI chr 5:116,039,222...116,099,064
Ensembl chr 5:116,039,616...116,098,618
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G |
Aldh5a1 |
aldehyde dehydrogenase 5 family, member A1 |
multiple interactions |
ISO |
[beauvericin co-treated with enniatins] results in decreased expression of ALDH5A1 protein |
CTD |
PMID:32407736 |
|
NCBI chr17:40,132,339...40,158,677
Ensembl chr17:40,130,883...40,158,677
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G |
Aldoa |
aldolase, fructose-bisphosphate A |
decreases expression |
ISO |
beauvericin results in decreased expression of ALDOA mRNA |
CTD |
PMID:29203277 |
|
NCBI chr 1:181,402,275...181,407,476
Ensembl chr 1:181,402,275...181,406,182
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G |
Anapc13 |
anaphase promoting complex subunit 13 |
multiple interactions |
ISO |
[beauvericin co-treated with enniatins] results in decreased expression of ANAPC13 protein |
CTD |
PMID:32407736 |
|
NCBI chr 8:103,205,520...103,213,936
Ensembl chr 8:103,205,520...103,213,936
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G |
Aprt |
adenine phosphoribosyl transferase |
decreases expression |
ISO |
beauvericin results in decreased expression of APRT mRNA |
CTD |
PMID:29203277 |
|
NCBI chr19:50,626,436...50,628,404
Ensembl chr19:50,626,202...50,628,431
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G |
Ar |
androgen receptor |
multiple interactions |
ISO |
beauvericin inhibits the reaction [Dihydrotestosterone results in increased expression of AR mRNA] |
CTD |
PMID:30716354 |
|
NCBI chr X:63,104,771...63,273,934
Ensembl chr X:63,104,771...63,273,925
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G |
Arhgdia |
Rho GDP dissociation inhibitor alpha |
decreases expression |
ISO |
beauvericin results in decreased expression of ARHGDIA mRNA |
CTD |
PMID:29203277 |
|
NCBI chr10:105,854,526...105,858,020
Ensembl chr10:105,854,533...105,858,023
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G |
Arpp21 |
cAMP regulated phosphoprotein 21 |
increases expression |
ISO |
beauvericin results in increased expression of ARPP21 mRNA |
CTD |
PMID:29203277 |
|
NCBI chr 8:112,034,636...112,199,273
Ensembl chr 8:112,034,642...112,194,297
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G |
Atp1a1 |
ATPase Na+/K+ transporting subunit alpha 1 |
multiple interactions |
ISO |
[beauvericin co-treated with enniatins] results in increased expression of ATP1A1 protein |
CTD |
PMID:32407736 |
|
NCBI chr 2:189,020,722...189,048,826
Ensembl chr 2:189,020,722...189,048,837
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G |
Atp1a3 |
ATPase Na+/K+ transporting subunit alpha 3 |
multiple interactions |
ISO |
[beauvericin co-treated with enniatins] results in decreased expression of ATP1A3 protein |
CTD |
PMID:32407736 |
|
NCBI chr 1:80,572,790...80,601,936
Ensembl chr 1:80,572,796...80,601,918
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G |
Atp5pb |
ATP synthase peripheral stalk-membrane subunit b |
multiple interactions |
ISO |
[beauvericin co-treated with enniatins] results in decreased expression of ATP5PB protein |
CTD |
PMID:32407736 |
|
NCBI chr 2:193,424,138...193,435,418
Ensembl chr 2:193,424,047...193,435,418
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G |
Atp5pf |
ATP synthase peripheral stalk subunit F6 |
multiple interactions |
ISO |
[beauvericin co-treated with enniatins] results in decreased expression of ATP5PF protein |
CTD |
PMID:32407736 |
|
NCBI chr11:23,881,594...23,889,581
Ensembl chr11:23,881,592...23,889,119
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G |
Bax |
BCL2 associated X, apoptosis regulator |
decreases expression multiple interactions |
ISO |
beauvericin results in decreased expression of BAX mRNA [zearalenol co-treated with beauvericin] results in increased expression of BAX mRNA |
CTD |
PMID:29203277 PMID:32956828 |
|
NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
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G |
Bcl2 |
BCL2, apoptosis regulator |
increases expression multiple interactions |
ISO |
beauvericin results in increased expression of BCL2 mRNA [zearalenol co-treated with beauvericin] results in increased expression of BCL2 mRNA |
CTD |
PMID:29203277 PMID:32956828 |
|
NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
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|
G |
Birc2 |
baculoviral IAP repeat-containing 2 |
increases expression |
ISO |
beauvericin results in increased expression of BIRC2 mRNA |
CTD |
PMID:29203277 |
|
NCBI chr 8:4,968,856...4,989,325
Ensembl chr 8:4,968,842...4,988,732
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|
G |
Birc3 |
baculoviral IAP repeat-containing 3 |
increases expression |
ISO |
beauvericin results in increased expression of BIRC3 mRNA |
CTD |
PMID:29203277 |
|
NCBI chr 8:5,000,844...5,028,470
Ensembl chr 8:5,000,845...5,015,802
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|
G |
Btf3l4 |
basic transcription factor 3-like 4 |
multiple interactions |
ISO |
[beauvericin co-treated with enniatins] results in decreased expression of BTF3L4 protein |
CTD |
PMID:32407736 |
|
NCBI chr 5:123,569,059...123,587,593
Ensembl chr 5:123,567,907...123,586,866
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|
G |
C1qtnf3 |
C1q and TNF related 3 |
decreases expression |
ISO |
beauvericin results in decreased expression of C1QTNF3 mRNA |
CTD |
PMID:29203277 |
|
NCBI chr 2:59,917,099...59,939,519
Ensembl chr 2:59,917,188...59,939,433
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G |
C1qtnf6 |
C1q and TNF related 6 |
increases expression |
ISO |
beauvericin results in increased expression of C1QTNF6 mRNA |
CTD |
PMID:29203277 |
|
NCBI chr 7:110,077,867...110,084,584
Ensembl chr 7:110,077,878...110,084,412
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|
G |
Caap1 |
caspase activity and apoptosis inhibitor 1 |
decreases expression |
ISO |
beauvericin results in decreased expression of CAAP1 mRNA |
CTD |
PMID:29203277 |
|
NCBI chr 5:109,313,253...109,414,323
Ensembl chr 5:109,361,912...109,414,314
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G |
Card11 |
caspase recruitment domain family, member 11 |
decreases expression |
ISO |
beauvericin results in decreased expression of CARD11 mRNA |
CTD |
PMID:29203277 |
|
NCBI chr12:13,620,979...13,758,115
Ensembl chr12:13,621,087...13,758,112
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G |
Casp3 |
caspase 3 |
increases activity multiple interactions |
EXP ISO |
beauvericin results in increased activity of CASP3 protein [zearalenol co-treated with beauvericin] results in increased expression of CASP3 mRNA |
CTD |
PMID:25178661 PMID:32956828 |
|
NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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|
G |
Casp7 |
caspase 7 |
increases activity |
EXP |
beauvericin results in increased activity of CASP7 protein |
CTD |
PMID:25178661 |
|
NCBI chr 1:255,437,195...255,476,737
Ensembl chr 1:255,437,172...255,476,729
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|
G |
Casp8 |
caspase 8 |
increases expression |
ISO |
beauvericin results in increased expression of CASP8 mRNA |
CTD |
PMID:29203277 |
|
NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
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G |
Casp9 |
caspase 9 |
increases expression |
ISO |
beauvericin results in increased expression of CASP9 mRNA |
CTD |
PMID:29203277 |
|
NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
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G |
Ccar2 |
cell cycle and apoptosis regulator 2 |
decreases expression |
ISO |
beauvericin results in decreased expression of CCAR2 mRNA |
CTD |
PMID:29203277 |
|
NCBI chr15:45,212,797...45,228,001
Ensembl chr15:45,212,803...45,227,636
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G |
Ccdc124 |
coiled-coil domain containing 124 |
decreases expression |
ISO |
beauvericin results in decreased expression of CCDC124 mRNA |
CTD |
PMID:29203277 |
|
NCBI chr16:18,566,745...18,572,564
Ensembl chr16:18,566,745...18,572,564
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G |
Ccdc180 |
coiled-coil domain containing 180 |
multiple interactions |
ISO |
[beauvericin co-treated with enniatins] results in decreased expression of CCDC180 protein |
CTD |
PMID:32407736 |
|
NCBI chr 5:60,154,883...60,223,508
Ensembl chr 5:60,154,910...60,223,522
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G |
Ccdc86 |
coiled-coil domain containing 86 |
decreases expression |
ISO |
beauvericin results in decreased expression of CCDC86 mRNA |
CTD |
PMID:29203277 |
|
NCBI chr 1:207,590,946...207,596,527
Ensembl chr 1:207,590,168...207,596,544
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G |
Ccng2 |
cyclin G2 |
multiple interactions |
ISO |
[beauvericin co-treated with enniatins] results in decreased expression of CCNG2 mRNA |
CTD |
PMID:31100301 |
|
NCBI chr14:14,804,321...14,812,819
Ensembl chr14:14,804,322...14,812,830
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|
G |
Cct5 |
chaperonin containing TCP1 subunit 5 |
multiple interactions |
ISO |
[beauvericin co-treated with enniatins] results in increased expression of CCT5 protein |
CTD |
PMID:32407736 |
|
NCBI chr 2:82,591,750...82,602,903
Ensembl chr 2:82,590,630...82,602,930
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|
G |
Cd47 |
Cd47 molecule |
multiple interactions |
ISO |
[beauvericin co-treated with enniatins] results in increased expression of CD47 protein |
CTD |
PMID:32407736 |
|
NCBI chr11:50,906,052...50,970,000
Ensembl chr11:50,906,177...50,969,425
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|
G |
Cd81 |
Cd81 molecule |
multiple interactions |
ISO |
[beauvericin co-treated with enniatins] results in increased expression of CD81 protein |
CTD |
PMID:32407736 |
|
NCBI chr 1:198,235,861...198,251,660
Ensembl chr 1:198,241,484...198,251,660
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|
G |
Cdk2ap2 |
cyclin-dependent kinase 2 associated protein 2 |
decreases expression |
ISO |
beauvericin results in decreased expression of CDK2AP2 mRNA |
CTD |
PMID:29203277 |
|
NCBI chr 1:201,391,056...201,393,137
Ensembl chr 1:201,391,466...201,393,137
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|
G |
Cebpb |
CCAAT/enhancer binding protein beta |
multiple interactions |
ISO |
[beauvericin co-treated with enniatins] results in decreased expression of CEBPB mRNA |
CTD |
PMID:31100301 |
|
NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473
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G |
Cflar |
CASP8 and FADD-like apoptosis regulator |
increases expression |
ISO |
beauvericin results in increased expression of CFLAR mRNA |
CTD |
PMID:29203277 |
|
NCBI chr 9:60,185,338...60,236,173
Ensembl chr 9:60,185,452...60,237,034
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G |
Chchd2 |
coiled-coil-helix-coiled-coil-helix domain containing 2 |
decreases expression |
ISO |
beauvericin results in decreased expression of CHCHD2 mRNA |
CTD |
PMID:29203277 |
|
NCBI chr12:26,828,738...26,834,762
Ensembl chr12:26,828,736...26,834,755
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G |
Ciapin1 |
cytokine induced apoptosis inhibitor 1 |
decreases expression |
ISO |
beauvericin results in decreased expression of CIAPIN1 mRNA |
CTD |
PMID:29203277 |
|
NCBI chr19:10,179,963...10,195,511
Ensembl chr19:10,180,100...10,195,503
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G |
Cnp |
2',3'-cyclic nucleotide 3' phosphodiesterase |
multiple interactions |
ISO |
[beauvericin co-treated with enniatins] results in increased expression of CNP protein |
CTD |
PMID:32407736 |
|
NCBI chr10:85,511,164...85,517,723
Ensembl chr10:85,511,160...85,517,720
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|
G |
Coa6 |
cytochrome c oxidase assembly factor 6 |
multiple interactions |
ISO |
[beauvericin co-treated with enniatins] results in decreased expression of COA6 protein |
CTD |
PMID:32407736 |
|
NCBI chr19:54,395,682...54,398,918
Ensembl chr19:54,395,742...54,399,407
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G |
Coro1c |
coronin 1C |
multiple interactions |
ISO |
[beauvericin co-treated with enniatins] results in increased expression of CORO1C protein |
CTD |
PMID:32407736 |
|
NCBI chr12:42,712,960...42,785,179
Ensembl chr12:42,712,991...42,785,179
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G |
Cotl1 |
coactosin-like F-actin binding protein 1 |
decreases expression |
ISO |
beauvericin results in decreased expression of COTL1 mRNA |
CTD |
PMID:29203277 |
|
NCBI chr19:47,871,689...47,906,010
Ensembl chr19:47,871,694...47,911,689
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G |
Cplane2 |
ciliogenesis and planar polarity effector complex subunit 2 |
multiple interactions |
ISO |
[beauvericin co-treated with enniatins] results in increased expression of CPLANE2 protein |
CTD |
PMID:32407736 |
|
NCBI chr 5:153,515,507...153,516,455
Ensembl chr 5:153,515,376...153,522,508
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G |
Cpne1 |
copine 1 |
decreases expression |
ISO |
beauvericin results in decreased expression of CPNE1 mRNA |
CTD |
PMID:29203277 |
|
NCBI chr 3:144,587,548...144,629,603
Ensembl chr 3:144,588,995...144,598,636
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|
G |
Crim1 |
cysteine rich transmembrane BMP regulator 1 |
multiple interactions |
ISO |
[beauvericin co-treated with enniatins] results in decreased expression of CRIM1 mRNA |
CTD |
PMID:31100301 |
|
NCBI chr 6:16,695,864...16,870,264
Ensembl chr 6:16,697,829...16,870,259
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G |
Csdc2 |
cold shock domain containing C2 |
multiple interactions |
ISO |
[beauvericin co-treated with enniatins] results in decreased expression of CSDC2 protein |
CTD |
PMID:32407736 |
|
NCBI chr 7:113,451,998...113,466,464
Ensembl chr 7:113,451,998...113,466,463
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|
G |
Csk |
C-terminal Src kinase |
decreases expression |
ISO |
beauvericin results in decreased expression of CSK mRNA |
CTD |
PMID:29203277 |
|
NCBI chr 8:58,029,748...58,048,742
Ensembl chr 8:58,029,749...58,048,292
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|
G |
Ctps1 |
CTP synthase 1 |
multiple interactions |
ISO |
[beauvericin co-treated with enniatins] results in decreased expression of CTPS1 protein |
CTD |
PMID:32407736 |
|
NCBI chr 5:134,125,022...134,154,155
Ensembl chr 5:134,125,025...134,154,180
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|
G |
Ctsd |
cathepsin D |
multiple interactions |
ISO |
[beauvericin co-treated with enniatins] results in decreased expression of CTSD protein |
CTD |
PMID:32407736 |
|
NCBI chr 1:197,527,467...197,539,343
Ensembl chr 1:197,527,467...197,539,488
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|
G |
Cyp4f39 |
cytochrome P450, family 4, subfamily f, polypeptide 39 |
multiple interactions |
ISO |
[beauvericin co-treated with enniatins] results in decreased expression of CYP4F22 protein |
CTD |
PMID:32407736 |
|
NCBI chr 7:11,426,806...11,505,553
Ensembl chr 7:11,433,371...11,536,181
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|
G |
Dcxr |
dicarbonyl and L-xylulose reductase |
multiple interactions |
ISO |
[beauvericin co-treated with enniatins] results in decreased expression of DCXR protein |
CTD |
PMID:32407736 |
|
NCBI chr10:106,006,404...106,008,294
|
|
G |
Ddias |
DNA damage-induced apoptosis suppressor |
decreases expression |
ISO |
beauvericin results in decreased expression of DDIAS mRNA |
CTD |
PMID:29203277 |
|
NCBI chr 1:146,906,150...146,930,462
Ensembl chr 1:146,906,154...146,930,462
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|
G |
Ddx47 |
DEAD-box helicase 47 |
multiple interactions |
ISO |
[beauvericin co-treated with enniatins] results in increased expression of DDX47 protein |
CTD |
PMID:32407736 |
|
NCBI chr 4:167,845,652...167,858,115
Ensembl chr 4:167,845,640...167,859,115
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|
G |
Dhrs7 |
dehydrogenase/reductase 7 |
multiple interactions |
ISO |
[beauvericin co-treated with enniatins] results in increased expression of DHRS7 protein |
CTD |
PMID:32407736 |
|
NCBI chr 6:91,332,259...91,347,856
Ensembl chr 6:91,251,323...91,347,892
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|
G |
Edem1 |
ER degradation enhancing alpha-mannosidase like protein 1 |
increases expression |
ISO |
beauvericin results in increased expression of EDEM1 mRNA |
CTD |
PMID:29203277 |
|
NCBI chr 4:141,797,631...141,829,717
Ensembl chr 4:141,797,701...141,829,717
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|
G |
Eif5a |
eukaryotic translation initiation factor 5A |
decreases expression |
ISO |
beauvericin results in decreased expression of EIF5A mRNA |
CTD |
PMID:29203277 |
|
NCBI chr10:54,640,104...54,644,845
Ensembl chr10:54,640,024...54,644,656
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G |
Faim2 |
Fas apoptotic inhibitory molecule 2 |
increases expression |
ISO |
beauvericin results in increased expression of FAIM2 mRNA |
CTD |
PMID:29203277 |
|
NCBI chr 7:130,632,368...130,659,353
Ensembl chr 7:130,633,348...130,659,168
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|
G |
Fmc1 |
formation of mitochondrial complex V assembly factor 1 |
multiple interactions |
ISO |
[beauvericin co-treated with enniatins] results in increased expression of FMC1 protein |
CTD |
PMID:32407736 |
|
NCBI chr 4:67,274,104...67,282,140
Ensembl chr 4:67,274,104...67,282,140
|
|
G |
Gaa |
alpha glucosidase |
multiple interactions |
ISO |
[beauvericin co-treated with enniatins] results in decreased expression of GAA protein |
CTD |
PMID:32407736 |
|
NCBI chr10:104,529,673...104,546,836
Ensembl chr10:104,529,747...104,546,836
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|
G |
Gna14 |
G protein subunit alpha 14 |
multiple interactions |
ISO |
[beauvericin co-treated with enniatins] results in decreased expression of GNA14 protein |
CTD |
PMID:32407736 |
|
NCBI chr 1:213,714,993...213,900,083
Ensembl chr 1:213,716,020...213,897,423
|
|
G |
Gnai3 |
G protein subunit alpha i3 |
multiple interactions |
ISO |
[beauvericin co-treated with enniatins] results in increased expression of GNAI3 protein |
CTD |
PMID:32407736 |
|
NCBI chr 2:195,742,765...195,780,720
Ensembl chr 2:195,742,642...195,780,742
|
|
G |
Gnb1 |
G protein subunit beta 1 |
multiple interactions |
ISO |
[beauvericin co-treated with enniatins] results in increased expression of GNB1 protein |
CTD |
PMID:32407736 |
|
NCBI chr 5:166,075,508...166,142,223
Ensembl chr 5:166,075,629...166,142,124
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|
G |
Golga1 |
golgin A1 |
multiple interactions |
ISO |
[beauvericin co-treated with enniatins] results in decreased expression of GOLGA1 protein |
CTD |
PMID:32407736 |
|
NCBI chr 3:22,765,690...22,812,637
Ensembl chr 3:22,767,761...22,812,585
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|
G |
Gpnmb |
glycoprotein nmb |
multiple interactions |
ISO |
[beauvericin co-treated with enniatins] results in increased expression of GPNMB protein |
CTD |
PMID:32407736 |
|
NCBI chr 4:78,010,247...78,031,491
Ensembl chr 4:78,010,197...78,049,367
|
|
G |
Gpr18 |
G protein-coupled receptor 18 |
multiple interactions |
ISO |
[beauvericin co-treated with enniatins] results in decreased expression of GPR18 mRNA |
CTD |
PMID:31100301 |
|
NCBI chr15:98,997,427...99,001,177
Ensembl chr15:98,997,259...99,001,470
|
|
G |
Hexb |
hexosaminidase subunit beta |
multiple interactions |
ISO |
[beauvericin co-treated with enniatins] results in decreased expression of HEXB protein |
CTD |
PMID:32407736 |
|
NCBI chr 2:28,483,997...28,504,165
Ensembl chr 2:28,484,012...28,504,223
|
|
G |
Hist2h2be |
histone cluster 2 H2B family member E |
multiple interactions |
ISO |
[beauvericin co-treated with enniatins] results in increased expression of HIST2H2BE protein |
CTD |
PMID:32407736 |
|
NCBI chr 2:183,780,449...183,783,030
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G |
Hmgcs1 |
3-hydroxy-3-methylglutaryl-CoA synthase 1 |
multiple interactions |
ISO |
[beauvericin co-treated with enniatins] results in decreased expression of HMGCS1 mRNA |
CTD |
PMID:31100301 |
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NCBI chr 2:51,649,368...51,667,100
Ensembl chr 2:51,649,497...51,667,100
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G |
Hnrnpm |
heterogeneous nuclear ribonucleoprotein M |
multiple interactions |
ISO |
[beauvericin co-treated with enniatins] results in increased expression of HNRNPM protein |
CTD |
PMID:32407736 |
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NCBI chr 7:14,438,703...14,476,781
Ensembl chr 7:14,438,688...14,476,762
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G |
Hnrnpu |
heterogeneous nuclear ribonucleoprotein U |
multiple interactions |
ISO |
[beauvericin co-treated with enniatins] results in increased expression of HNRNPU protein |
CTD |
PMID:32407736 |
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NCBI chr13:90,069,058...90,086,905
Ensembl chr13:90,074,181...90,086,588
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G |
Hspa5 |
heat shock protein family A (Hsp70) member 5 |
multiple interactions |
ISO |
[beauvericin co-treated with enniatins] results in decreased expression of HSPA5 mRNA |
CTD |
PMID:31100301 |
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NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
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G |
Immt |
inner membrane mitochondrial protein |
multiple interactions |
ISO |
[beauvericin co-treated with enniatins] results in decreased expression of IMMT protein |
CTD |
PMID:32407736 |
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NCBI chr 4:103,880,482...103,919,116
Ensembl chr 4:103,880,459...103,919,109
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G |
Insig1 |
insulin induced gene 1 |
increases expression |
ISO |
beauvericin results in increased expression of INSIG1 mRNA |
CTD |
PMID:29203277 |
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NCBI chr 4:7,315,494...7,323,972
Ensembl chr 4:7,315,495...7,323,952
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G |
Islr2 |
immunoglobulin superfamily containing leucine-rich repeat 2 |
multiple interactions |
ISO |
[beauvericin co-treated with enniatins] results in decreased expression of ISLR2 protein |
CTD |
PMID:32407736 |
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NCBI chr 8:58,608,165...58,616,246
Ensembl chr 8:58,608,709...58,614,650
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G |
Itgb1 |
integrin subunit beta 1 |
multiple interactions |
ISO |
[beauvericin co-treated with enniatins] results in increased expression of ITGB1 protein |
CTD |
PMID:32407736 |
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NCBI chr19:56,705,123...56,753,199
Ensembl chr19:56,705,171...56,753,195
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G |
Klf12 |
KLF transcription factor 12 |
multiple interactions |
ISO |
[beauvericin co-treated with enniatins] results in decreased expression of KLF12 protein |
CTD |
PMID:32407736 |
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NCBI chr15:76,628,778...77,062,000
Ensembl chr15:76,637,654...77,062,056
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G |
Kpnb1 |
karyopherin subunit beta 1 |
multiple interactions |
ISO |
[beauvericin co-treated with enniatins] results in decreased expression of KPNB1 protein |
CTD |
PMID:32407736 |
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NCBI chr10:82,145,662...82,174,437
Ensembl chr10:82,145,420...82,174,605
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G |
Krt16 |
keratin 16 |
multiple interactions |
ISO |
[beauvericin co-treated with enniatins] results in decreased expression of KRT16 protein |
CTD |
PMID:32407736 |
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NCBI chr10:85,168,357...85,171,744
Ensembl chr10:85,066,802...85,171,799
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G |
Krt27 |
keratin 27 |
multiple interactions |
ISO |
[beauvericin co-treated with enniatins] results in increased expression of KRT27 protein |
CTD |
PMID:32407736 |
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NCBI chr10:84,298,684...84,303,967
Ensembl chr10:84,298,508...84,303,967
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G |
Krt5 |
keratin 5 |
multiple interactions |
ISO |
[beauvericin co-treated with enniatins] results in increased expression of KRT5 protein |
CTD |
PMID:32407736 |
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NCBI chr 7:132,846,355...132,851,986
Ensembl chr 7:132,846,136...132,851,850
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G |
Krt76 |
keratin 76 |
multiple interactions |
ISO |
[beauvericin co-treated with enniatins] results in decreased expression of KRT76 protein |
CTD |
PMID:32407736 |
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NCBI chr 7:133,016,990...133,025,414
Ensembl chr 7:133,016,992...133,025,496
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G |
Lamp2 |
lysosomal-associated membrane protein 2 |
multiple interactions |
ISO |
[beauvericin co-treated with enniatins] results in decreased expression of LAMP2 protein |
CTD |
PMID:32407736 |
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NCBI chr X:117,173,097...117,222,090
Ensembl chr X:117,057,606...117,260,522
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G |
Lat |
linker for activation of T cells |
decreases expression |
ISO |
beauvericin results in decreased expression of LAT mRNA |
CTD |
PMID:29203277 |
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NCBI chr 1:180,936,536...180,941,561
Ensembl chr 1:180,936,534...180,941,578
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G |
Mapk1 |
mitogen activated protein kinase 1 |
decreases phosphorylation |
EXP |
beauvericin results in decreased phosphorylation of MAPK1 protein |
CTD |
PMID:25178661 |
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NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
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G |
Mapk3 |
mitogen activated protein kinase 3 |
decreases phosphorylation |
EXP |
beauvericin results in decreased phosphorylation of MAPK3 protein |
CTD |
PMID:25178661 |
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NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
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G |
Matn4 |
matrilin 4 |
decreases expression |
ISO |
beauvericin results in decreased expression of MATN4 mRNA |
CTD |
PMID:29203277 |
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NCBI chr 3:153,120,605...153,135,628
Ensembl chr 3:153,120,632...153,135,865
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G |
Mavs |
mitochondrial antiviral signaling protein |
increases expression |
ISO |
beauvericin results in increased expression of MAVS mRNA |
CTD |
PMID:29203277 |
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NCBI chr 3:118,451,650...118,466,094
Ensembl chr 3:118,451,743...118,466,094
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G |
Med6 |
mediator complex subunit 6 |
multiple interactions |
ISO |
[beauvericin co-treated with enniatins] results in decreased expression of MED6 protein |
CTD |
PMID:32407736 |
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NCBI chr 6:101,270,410...101,283,929
Ensembl chr 6:101,270,410...101,283,876
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G |
Moap1 |
modulator of apoptosis 1 |
increases expression |
ISO |
beauvericin results in increased expression of MOAP1 mRNA |
CTD |
PMID:29203277 |
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NCBI chr 6:121,882,565...121,884,500
Ensembl chr 6:121,882,366...121,898,643
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G |
Mrpl12 |
mitochondrial ribosomal protein L12 |
decreases expression multiple interactions |
ISO |
beauvericin results in decreased expression of MRPL12 mRNA [beauvericin co-treated with enniatins] results in decreased expression of MRPL12 mRNA |
CTD |
PMID:29203277 PMID:31100301 |
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NCBI chr10:105,758,410...105,762,913
Ensembl chr10:105,758,410...105,762,913
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G |
Mrpl4 |
mitochondrial ribosomal protein L4 |
decreases expression |
ISO |
beauvericin results in decreased expression of MRPL4 mRNA |
CTD |
PMID:29203277 |
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NCBI chr 8:19,539,593...19,545,608
Ensembl chr 8:19,539,593...19,545,608
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G |
Mt-atp6 |
mitochondrially encoded ATP synthase membrane subunit 6 |
decreases expression multiple interactions |
ISO |
beauvericin results in decreased expression of ATP6 mRNA [beauvericin co-treated with enniatins co-treated with ochratoxin A] results in increased expression of ATP6 mRNA; [beauvericin co-treated with enniatins] results in decreased expression of ATP6 mRNA; [beauvericin co-treated with enniatins] results in increased expression of ATP6 mRNA; [Plant Extracts co-treated with beauvericin co-treated with enniatins] results in decreased expression of ATP6 mRNA; [Plant Extracts co-treated with beauvericin] results in decreased expression of ATP6 mRNA; [Plant Extracts co-treated with ochratoxin A co-treated with Zearalenone co-treated with beauvericin] results in decreased expression of ATP6 mRNA |
CTD |
PMID:29203277 PMID:31100301 PMID:34015425 |
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NCBI chr MT:7,919...8,599
Ensembl chr MT:7,919...8,599
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G |
Mt-atp8 |
mitochondrially encoded ATP synthase membrane subunit 8 |
decreases expression multiple interactions |
ISO |
beauvericin results in decreased expression of ATP8 mRNA [beauvericin co-treated with enniatins co-treated with ochratoxin A] results in decreased expression of ATP8 mRNA; [beauvericin co-treated with enniatins] affects the expression of ATP8 mRNA; [beauvericin co-treated with enniatins] results in decreased expression of ATP8 mRNA; [Plant Extracts co-treated with beauvericin co-treated with enniatins] results in decreased expression of ATP8 mRNA; [Plant Extracts co-treated with beauvericin] results in decreased expression of ATP8 mRNA; [Plant Extracts co-treated with ochratoxin A co-treated with Zearalenone co-treated with beauvericin] results in decreased expression of ATP8 mRNA |
CTD |
PMID:29203277 PMID:31100301 PMID:34015425 |
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NCBI chr MT:7,758...7,961
Ensembl chr MT:7,758...7,961
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G |
Mt-co1 |
mitochondrially encoded cytochrome c oxidase I |
multiple interactions decreases expression |
ISO |
[beauvericin co-treated with enniatins co-treated with ochratoxin A] results in decreased expression of COX1 mRNA; [beauvericin co-treated with enniatins] affects the expression of COX1 mRNA; [beauvericin co-treated with enniatins] results in decreased expression of COX1 mRNA; [Plant Extracts co-treated with beauvericin co-treated with enniatins] results in decreased expression of COX1 mRNA; [Plant Extracts co-treated with beauvericin] results in decreased expression of COX1 mRNA; [Plant Extracts co-treated with ochratoxin A co-treated with Zearalenone co-treated with beauvericin] results in decreased expression of COX1 mRNA beauvericin results in decreased expression of COX1 mRNA |
CTD |
PMID:31100301 PMID:34015425 |
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NCBI chr MT:5,323...6,867
Ensembl chr MT:5,323...6,867
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G |
Mt-co3 |
mitochondrially encoded cytochrome c oxidase III |
decreases expression multiple interactions |
ISO |
beauvericin results in decreased expression of COX3 mRNA [beauvericin co-treated with enniatins co-treated with ochratoxin A] results in decreased expression of COX3 mRNA; [beauvericin co-treated with enniatins] results in decreased expression of COX3 mRNA; [Plant Extracts co-treated with beauvericin co-treated with enniatins] results in decreased expression of COX3 mRNA; [Plant Extracts co-treated with beauvericin] results in decreased expression of COX3 mRNA; [Plant Extracts co-treated with ochratoxin A co-treated with Zearalenone co-treated with beauvericin] results in decreased expression of COX3 mRNA |
CTD |
PMID:29203277 PMID:31100301 PMID:34015425 |
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NCBI chr MT:8,599...9,382
Ensembl chr MT:8,599...9,382
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G |
Mt-cyb |
mitochondrially encoded cytochrome b |
decreases expression |
ISO |
beauvericin results in decreased expression of CYTB mRNA |
CTD |
PMID:29203277 |
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NCBI chr MT:14,136...15,278
Ensembl chr MT:14,136...15,278
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G |
Mt-nd2 |
mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 2 |
decreases expression increases expression multiple interactions |
ISO |
beauvericin results in decreased expression of ND2 mRNA beauvericin results in increased expression of ND2 mRNA [beauvericin co-treated with enniatins co-treated with ochratoxin A] results in increased expression of ND2 mRNA; [beauvericin co-treated with enniatins] results in decreased expression of ND2 mRNA; [beauvericin co-treated with enniatins] results in increased expression of ND2 mRNA; [Plant Extracts co-treated with beauvericin co-treated with enniatins] results in increased expression of ND2 mRNA; [Plant Extracts co-treated with beauvericin] results in increased expression of ND2 mRNA; [Plant Extracts co-treated with ochratoxin A co-treated with Zearalenone co-treated with beauvericin] results in increased expression of ND2 mRNA |
CTD |
PMID:29203277 PMID:31100301 PMID:34015425 |
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NCBI chr MT:3,904...4,942
Ensembl chr MT:3,904...4,942
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G |
Mt-nd3 |
mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 3 |
decreases expression increases expression multiple interactions |
ISO |
beauvericin results in decreased expression of ND3 mRNA beauvericin results in increased expression of ND3 mRNA [beauvericin co-treated with enniatins co-treated with ochratoxin A] results in increased expression of ND3 mRNA; [beauvericin co-treated with enniatins] results in decreased expression of ND3 mRNA; [beauvericin co-treated with enniatins] results in increased expression of ND3 mRNA; [Plant Extracts co-treated with beauvericin co-treated with enniatins] results in increased expression of ND3 mRNA; [Plant Extracts co-treated with beauvericin] results in increased expression of ND3 mRNA; [Plant Extracts co-treated with ochratoxin A co-treated with Zearalenone co-treated with beauvericin] results in increased expression of ND3 mRNA |
CTD |
PMID:29203277 PMID:31100301 PMID:34015425 |
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NCBI chr MT:9,451...9,798
Ensembl chr MT:9,451...9,798
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G |
Mt-nd4 |
mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 4 |
decreases expression multiple interactions |
ISO |
beauvericin results in decreased expression of ND4 mRNA [beauvericin co-treated with enniatins co-treated with ochratoxin A] results in decreased expression of ND4 mRNA; [beauvericin co-treated with enniatins] results in decreased expression of ND4 mRNA; [beauvericin co-treated with enniatins] results in increased expression of ND4 mRNA; [Plant Extracts co-treated with beauvericin co-treated with enniatins] results in increased expression of ND4 mRNA; [Plant Extracts co-treated with beauvericin] results in increased expression of ND4 mRNA; [Plant Extracts co-treated with ochratoxin A co-treated with Zearalenone co-treated with beauvericin] results in decreased expression of ND4 mRNA |
CTD |
PMID:29203277 PMID:31100301 PMID:34015425 |
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NCBI chr MT:10,160...11,537
Ensembl chr MT:10,160...11,537
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G |
Mt-nd4l |
mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 4L |
decreases expression increases expression multiple interactions |
ISO |
beauvericin results in decreased expression of ND4L mRNA beauvericin results in increased expression of ND4L mRNA [beauvericin co-treated with enniatins co-treated with ochratoxin A] results in increased expression of ND4L mRNA; [beauvericin co-treated with enniatins] results in decreased expression of ND4L mRNA; [Plant Extracts co-treated with beauvericin co-treated with enniatins] results in increased expression of ND4L mRNA; [Plant Extracts co-treated with beauvericin] results in increased expression of ND4L mRNA |
CTD |
PMID:29203277 PMID:31100301 PMID:34015425 |
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NCBI chr MT:9,870...10,166
Ensembl chr MT:9,870...10,166
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G |
Mt-nd5 |
mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 5 |
decreases expression increases expression multiple interactions |
ISO |
beauvericin results in decreased expression of ND5 mRNA beauvericin results in increased expression of ND5 mRNA [beauvericin co-treated with enniatins co-treated with ochratoxin A] results in increased expression of ND5 mRNA; [beauvericin co-treated with enniatins] results in decreased expression of ND5 mRNA; [Plant Extracts co-treated with beauvericin co-treated with enniatins] results in increased expression of ND5 mRNA; [Plant Extracts co-treated with beauvericin] results in increased expression of ND5 mRNA |
CTD |
PMID:29203277 PMID:31100301 PMID:34015425 |
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NCBI chr MT:11,736...13,565
Ensembl chr MT:11,736...13,565
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G |
Mt-nd6 |
mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 6 |
decreases expression multiple interactions |
ISO |
beauvericin results in decreased expression of ND6 mRNA [beauvericin co-treated with enniatins co-treated with ochratoxin A] results in decreased expression of ND6 mRNA; [beauvericin co-treated with enniatins] results in decreased expression of ND6 mRNA; [Plant Extracts co-treated with beauvericin co-treated with enniatins] results in increased expression of ND6 mRNA; [Plant Extracts co-treated with beauvericin] results in increased expression of ND6 mRNA |
CTD |
PMID:34015425 |
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NCBI chr MT:13,543...14,061
Ensembl chr MT:13,543...14,061
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G |
Mtrf1l |
mitochondrial translation release factor 1 like |
multiple interactions |
ISO |
[beauvericin co-treated with enniatins] results in decreased expression of MTRF1L protein |
CTD |
PMID:32407736 |
|
NCBI chr 1:42,208,553...42,221,020
Ensembl chr 1:42,210,583...42,220,836
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G |
Myo18a |
myosin XVIIIa |
increases expression |
ISO |
beauvericin results in increased expression of MYO18A mRNA |
CTD |
PMID:29203277 |
|
NCBI chr10:62,654,218...62,755,464
Ensembl chr10:62,654,281...62,755,468
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G |
Nars1 |
asparaginyl-tRNA synthetase 1 |
multiple interactions |
ISO |
[beauvericin co-treated with enniatins] results in increased expression of NARS1 protein |
CTD |
PMID:32407736 |
|
NCBI chr18:57,989,308...58,005,639
Ensembl chr18:57,989,308...58,005,622
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G |
Nars2 |
asparaginyl-tRNA synthetase 2, mitochondrial |
multiple interactions |
ISO |
[beauvericin co-treated with enniatins] results in increased expression of NARS2 protein |
CTD |
PMID:32407736 |
|
NCBI chr 1:151,300,446...151,412,069
Ensembl chr 1:151,300,467...151,413,521
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G |
Ndrg1 |
N-myc downstream regulated 1 |
multiple interactions |
ISO |
[beauvericin co-treated with enniatins] results in increased expression of NDRG1 protein |
CTD |
PMID:32407736 |
|
NCBI chr 7:98,684,487...98,725,869
Ensembl chr 7:98,684,487...98,725,880
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G |
Nlrp1a |
NLR family, pyrin domain containing 1A |
increases expression |
ISO |
beauvericin results in increased expression of NLRP1 mRNA |
CTD |
PMID:29203277 |
|
NCBI chr10:55,778,560...55,833,639
Ensembl chr10:55,778,560...55,825,180
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G |
Nod1 |
nucleotide-binding oligomerization domain containing 1 |
increases expression |
ISO |
beauvericin results in increased expression of NOD1 mRNA |
CTD |
PMID:29203277 |
|
NCBI chr 4:84,060,871...84,111,668
Ensembl chr 4:84,060,880...84,111,404
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G |
Nol3 |
nucleolar protein 3 |
increases expression |
ISO |
beauvericin results in increased expression of NOL3 mRNA |
CTD |
PMID:29203277 |
|
NCBI chr19:33,154,061...33,158,250
Ensembl chr19:33,154,062...33,158,250
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G |
Nqo1 |
NAD(P)H quinone dehydrogenase 1 |
multiple interactions |
ISO |
[beauvericin co-treated with enniatins] results in decreased expression of NQO1 mRNA |
CTD |
PMID:31100301 |
|
NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
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G |
Nudt1 |
nudix hydrolase 1 |
multiple interactions |
ISO |
[beauvericin co-treated with enniatins] results in increased expression of NUDT1 protein |
CTD |
PMID:32407736 |
|
NCBI chr12:14,302,514...14,309,559
Ensembl chr12:14,302,694...14,305,826
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G |
Oga |
O-GlcNAcase |
increases expression |
ISO |
beauvericin results in increased expression of OGA mRNA |
CTD |
PMID:29203277 |
|
NCBI chr 1:244,598,285...244,633,835
Ensembl chr 1:244,598,292...244,634,359
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G |
Ogt |
O-linked N-acetylglucosamine (GlcNAc) transferase |
increases expression |
ISO |
beauvericin results in increased expression of OGT mRNA |
CTD |
PMID:29203277 |
|
NCBI chr X:66,771,278...66,816,148
Ensembl chr X:66,771,349...66,816,146
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G |
Osgin1 |
oxidative stress induced growth inhibitor 1 |
multiple interactions increases expression |
ISO |
[beauvericin co-treated with enniatins co-treated with ochratoxin A] results in decreased expression of OSGIN1 mRNA; [beauvericin co-treated with enniatins] results in decreased expression of OSGIN1 mRNA; [Plant Extracts co-treated with beauvericin] results in increased expression of OSGIN1 mRNA beauvericin results in increased expression of OSGIN1 mRNA |
CTD |
PMID:31100301 PMID:34015425 |
|
NCBI chr19:47,471,750...47,500,517
Ensembl chr19:47,492,171...47,500,516
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G |
Ostc |
oligosaccharyltransferase complex non-catalytic subunit |
multiple interactions |
ISO |
[beauvericin co-treated with enniatins] results in increased expression of OSTC protein |
CTD |
PMID:32407736 |
|
NCBI chr 2:219,250,549...219,266,076
Ensembl chr 2:219,236,952...219,266,107
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G |
Parvg |
parvin, gamma |
multiple interactions |
ISO |
[beauvericin co-treated with enniatins] results in increased expression of PARVG protein |
CTD |
PMID:32407736 |
|
NCBI chr 7:115,456,183...115,475,707
Ensembl chr 7:115,456,209...115,475,104
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G |
Pawr |
pro-apoptotic WT1 regulator |
decreases expression |
ISO |
beauvericin results in decreased expression of PAWR mRNA |
CTD |
PMID:29203277 |
|
NCBI chr 7:43,645,028...43,725,033
Ensembl chr 7:43,645,084...43,725,028
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G |
Pdcd11 |
programmed cell death 11 |
decreases expression |
ISO |
beauvericin results in decreased expression of PDCD11 mRNA |
CTD |
PMID:29203277 |
|
NCBI chr 1:245,980,840...246,021,999
Ensembl chr 1:245,980,880...246,021,999
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G |
Pdcd2 |
programmed cell death 2 |
decreases expression |
ISO |
beauvericin results in decreased expression of PDCD2 mRNA |
CTD |
PMID:29203277 |
|
NCBI chr 1:56,484,947...56,490,437
Ensembl chr 1:56,463,931...56,490,437
|
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G |
Pdcd2l |
programmed cell death 2-like |
increases expression |
ISO |
beauvericin results in increased expression of PDCD2L mRNA |
CTD |
PMID:29203277 |
|
NCBI chr 1:86,810,292...86,822,554
Ensembl chr 1:86,810,292...86,822,554
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G |
Pdcd4 |
programmed cell death 4 |
decreases expression |
ISO |
beauvericin results in decreased expression of PDCD4 mRNA |
CTD |
PMID:29203277 |
|
NCBI chr 1:252,921,342...252,944,278
Ensembl chr 1:252,921,392...252,944,275
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G |
Pdcd5 |
programmed cell death 5 |
increases expression |
ISO |
beauvericin results in increased expression of PDCD5 mRNA |
CTD |
PMID:29203277 |
|
NCBI chr 1:88,305,869...88,311,200
Ensembl chr 1:88,305,869...88,311,200
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G |
Pdcd6ip |
programmed cell death 6 interacting protein |
increases expression |
ISO |
beauvericin results in increased expression of PDCD6IP mRNA |
CTD |
PMID:29203277 |
|
NCBI chr 8:113,590,998...113,646,795
Ensembl chr 8:113,590,998...113,646,773
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G |
Pdia4 |
protein disulfide isomerase family A, member 4 |
decreases expression |
ISO |
beauvericin results in decreased expression of PDIA4 mRNA |
CTD |
PMID:29203277 |
|
NCBI chr 4:76,803,198...76,822,245
Ensembl chr 4:76,803,198...76,822,107
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G |
Pfn1 |
profilin 1 |
decreases expression multiple interactions |
ISO |
beauvericin results in decreased expression of PFN1 mRNA [beauvericin co-treated with enniatins] results in increased expression of PFN1 protein |
CTD |
PMID:29203277 PMID:32407736 |
|
NCBI chr10:55,365,263...55,367,968
Ensembl chr10:55,365,262...55,527,631
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G |
Pgam1 |
phosphoglycerate mutase 1 |
multiple interactions |
ISO |
[beauvericin co-treated with enniatins] results in increased expression of PGAM1 protein |
CTD |
PMID:32407736 |
|
NCBI chr 1:240,723,832...240,731,443
Ensembl chr 1:240,723,920...240,738,452
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G |
Pgk1 |
phosphoglycerate kinase 1 |
multiple interactions |
ISO |
[beauvericin co-treated with enniatins] results in increased expression of PGK1 protein |
CTD |
PMID:32407736 |
|
NCBI chr X:71,271,454...71,287,429
Ensembl chr X:71,271,440...71,287,418
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G |
Phgdh |
phosphoglycerate dehydrogenase |
multiple interactions |
ISO |
[beauvericin co-treated with enniatins] results in increased expression of PHGDH protein |
CTD |
PMID:32407736 |
|
NCBI chr 2:185,906,964...185,936,160
Ensembl chr 2:185,906,966...185,935,944
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|
G |
Phka2 |
phosphorylase kinase regulatory subunit alpha 2 |
multiple interactions |
ISO |
[beauvericin co-treated with enniatins] results in decreased expression of PHKA2 protein |
CTD |
PMID:32407736 |
|
NCBI chr X:34,170,959...34,293,498
Ensembl chr X:34,171,323...34,293,466
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G |
Pidd1 |
p53-induced death domain protein 1 |
decreases expression |
ISO |
beauvericin results in decreased expression of PIDD1 mRNA |
CTD |
PMID:29203277 |
|
NCBI chr 1:196,536,815...196,542,808
Ensembl chr 1:196,536,834...196,542,699
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G |
Plk1 |
polo-like kinase 1 |
decreases expression |
ISO |
beauvericin results in decreased expression of PLK1 mRNA |
CTD |
PMID:29203277 |
|
NCBI chr 1:176,716,420...176,726,400
Ensembl chr 1:176,716,420...176,726,400
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G |
Pls3 |
plastin 3 |
multiple interactions |
ISO |
[beauvericin co-treated with enniatins] results in decreased expression of PLS3 protein |
CTD |
PMID:32407736 |
|
NCBI chr X:111,589,193...111,683,908
Ensembl chr X:111,589,254...111,683,891
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|
G |
Ppa1 |
inorganic pyrophosphatase 1 |
multiple interactions |
ISO |
[beauvericin co-treated with enniatins] results in increased expression of PPA1 protein |
CTD |
PMID:32407736 |
|
NCBI chr20:29,590,733...29,617,711
Ensembl chr20:29,590,707...29,619,215
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G |
Ppan |
peter pan homolog |
decreases expression |
ISO |
beauvericin results in decreased expression of PPAN mRNA |
CTD |
PMID:29203277 |
|
NCBI chr 8:19,423,908...19,427,941
Ensembl chr 8:19,423,961...19,427,938
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G |
Ppib |
peptidylprolyl isomerase B |
decreases expression |
ISO |
beauvericin results in decreased expression of PPIB mRNA |
CTD |
PMID:29203277 |
|
NCBI chr 8:66,603,877...66,609,734
Ensembl chr 8:66,603,861...66,630,428
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|
G |
Ppp1r14b |
protein phosphatase 1, regulatory (inhibitor) subunit 14B |
decreases expression |
ISO |
beauvericin results in decreased expression of PPP1R14B mRNA |
CTD |
PMID:29203277 |
|
NCBI chr 1:204,165,210...204,167,320
Ensembl chr 1:204,163,299...204,167,319
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G |
Ppt1 |
palmitoyl-protein thioesterase 1 |
multiple interactions |
ISO |
[beauvericin co-treated with enniatins] results in decreased expression of PPT1 protein |
CTD |
PMID:32407736 |
|
NCBI chr 5:135,121,176...135,141,076
Ensembl chr 5:135,121,163...135,142,048
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G |
Prkca |
protein kinase C, alpha |
multiple interactions |
ISO |
[beauvericin co-treated with enniatins] results in increased expression of PRKCA protein |
CTD |
PMID:32407736 |
|
NCBI chr10:92,889,390...93,288,013
Ensembl chr10:92,894,012...93,288,012
|
|
G |
Psma5 |
proteasome 20S subunit alpha 5 |
multiple interactions |
ISO |
[beauvericin co-treated with enniatins] results in increased expression of PSMA5 protein |
CTD |
PMID:32407736 |
|
NCBI chr 2:195,896,369...195,919,733
Ensembl chr 2:195,896,365...195,919,731
|
|
G |
Psme4 |
proteasome activator subunit 4 |
multiple interactions |
ISO |
[beauvericin co-treated with enniatins] results in decreased expression of PSME4 protein |
CTD |
PMID:32407736 |
|
NCBI chr14:104,505,716...104,609,410
Ensembl chr14:104,505,716...104,609,408
|
|
G |
Ptges3 |
prostaglandin E synthase 3 |
multiple interactions |
ISO |
[beauvericin co-treated with enniatins] results in increased expression of PTGES3 protein |
CTD |
PMID:32407736 |
|
NCBI chr 7:490,698...507,759
Ensembl chr 7:490,656...508,084
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|
G |
Ptprc |
protein tyrosine phosphatase, receptor type, C |
multiple interactions |
ISO |
[beauvericin co-treated with enniatins] results in increased expression of PTPRC protein |
CTD |
PMID:32407736 |
|
NCBI chr13:49,596,193...49,708,283
Ensembl chr13:49,596,193...49,708,692
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|
G |
Rab11fip5 |
RAB11 family interacting protein 5 |
multiple interactions |
ISO |
[beauvericin co-treated with enniatins] results in decreased expression of RAB11FIP5 protein |
CTD |
PMID:32407736 |
|
NCBI chr 4:117,871,301...117,908,819
Ensembl chr 4:117,871,308...117,908,741
|
|
G |
Rab5a |
RAB5A, member RAS oncogene family |
multiple interactions |
ISO |
[beauvericin co-treated with enniatins] results in increased expression of RAB5A protein |
CTD |
PMID:32407736 |
|
NCBI chr 9:6,483,906...6,512,877
Ensembl chr 9:6,484,469...6,512,873
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G |
Rac3 |
Rac family small GTPase 3 |
multiple interactions |
ISO |
[beauvericin co-treated with enniatins] results in increased expression of RAC3 protein |
CTD |
PMID:32407736 |
|
NCBI chr10:106,002,808...106,005,244
Ensembl chr10:105,993,087...106,005,260
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|
G |
Rap1a |
RAP1A, member of RAS oncogene family |
multiple interactions |
ISO |
[beauvericin co-treated with enniatins] results in increased expression of RAP1A protein |
CTD |
PMID:32407736 |
|
NCBI chr 2:193,208,631...193,286,513
Ensembl chr 2:193,208,635...193,286,501
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G |
Relt |
RELT, TNF receptor |
decreases expression |
ISO |
beauvericin results in decreased expression of RELT mRNA |
CTD |
PMID:29203277 |
|
NCBI chr 1:155,206,976...155,224,609
Ensembl chr 1:155,206,976...155,214,196
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G |
Rp2 |
RP2 activator of ARL3 GTPase |
multiple interactions |
ISO |
[beauvericin co-treated with enniatins] results in increased expression of RP2 protein |
CTD |
PMID:32407736 |
|
NCBI chr X:1,872,581...1,916,704
Ensembl chr X:1,873,306...1,916,688
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G |
Rpl37a |
ribosomal protein L37A |
multiple interactions |
ISO |
[beauvericin co-treated with enniatins] results in increased expression of RPL37A protein |
CTD |
PMID:32407736 |
|
NCBI chr 9:74,298,861...74,300,926
|
|
G |
Rpl5 |
ribosomal protein L5 |
multiple interactions |
ISO |
[beauvericin co-treated with enniatins] results in increased expression of RPL5 protein |
CTD |
PMID:32407736 |
|
NCBI chr14:1,843,856...1,850,301
Ensembl chr14:1,843,770...1,850,290
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G |
Rpl8 |
ribosomal protein L8 |
multiple interactions |
ISO |
[beauvericin co-treated with enniatins] results in decreased expression of RPL8 protein |
CTD |
PMID:32407736 |
|
NCBI chr 7:108,626,194...108,628,485
Ensembl chr 7:108,622,324...108,628,482
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|
G |
Rxra |
retinoid X receptor alpha |
multiple interactions |
ISO |
[beauvericin co-treated with enniatins] results in increased expression of RXRA protein |
CTD |
PMID:32407736 |
|
NCBI chr 3:10,989,832...11,076,366
Ensembl chr 3:10,989,832...11,073,712
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|
G |
Scml2 |
Scm polycomb group protein like 2 |
multiple interactions |
ISO |
[beauvericin co-treated with enniatins] results in decreased expression of SCML2 protein |
CTD |
PMID:32407736 |
|
NCBI chr X:33,523,179...33,677,672
Ensembl chr X:33,524,530...33,652,742
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|
G |
Sdf2l1 |
stromal cell-derived factor 2-like 1 |
multiple interactions |
ISO |
[beauvericin co-treated with enniatins] results in decreased expression of SDF2L1 protein |
CTD |
PMID:32407736 |
|
NCBI chr11:83,872,659...83,874,902
Ensembl chr11:83,872,659...83,874,902
|
|
G |
Sdr42e2 |
short chain dehydrogenase/reductase family 42E, member 2 |
multiple interactions |
ISO |
[beauvericin co-treated with enniatins] results in increased expression of SDR42E2 protein |
CTD |
PMID:32407736 |
|
NCBI chr 1:175,361,630...175,382,769
Ensembl chr 1:175,362,150...175,382,050
|
|
G |
Sec13 |
SEC13 homolog, nuclear pore and COPII coat complex component |
decreases expression |
ISO |
beauvericin results in decreased expression of SEC13 mRNA |
CTD |
PMID:29203277 |
|
NCBI chr 4:146,877,739...146,891,130
Ensembl chr 4:146,875,524...146,891,173
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G |
Siva1 |
SIVA1, apoptosis-inducing factor |
decreases expression |
ISO |
beauvericin results in decreased expression of SIVA1 mRNA |
CTD |
PMID:29203277 |
|
NCBI chr 6:131,705,312...131,709,697
Ensembl chr 6:131,705,323...131,709,690
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G |
Slc1a5 |
solute carrier family 1 member 5 |
multiple interactions |
ISO |
[beauvericin co-treated with enniatins] results in increased expression of SLC1A5 protein |
CTD |
PMID:32407736 |
|
NCBI chr 1:77,456,849...77,470,952
Ensembl chr 1:77,456,694...77,470,952
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|
G |
Slc2a1 |
solute carrier family 2 member 1 |
multiple interactions |
ISO |
[beauvericin co-treated with enniatins] results in increased expression of SLC2A1 protein |
CTD |
PMID:32407736 |
|
NCBI chr 5:132,717,196...132,745,416
Ensembl chr 5:132,717,196...132,745,416
|
|
G |
Slc3a2 |
solute carrier family 3 member 2 |
multiple interactions |
ISO |
[beauvericin co-treated with enniatins] results in increased expression of SLC3A2 protein |
CTD |
PMID:32407736 |
|
NCBI chr 1:205,604,468...205,618,931
Ensembl chr 1:205,604,468...205,618,931
|
|
G |
Snrpd2 |
small nuclear ribonucleoprotein D2 polypeptide |
multiple interactions |
ISO |
[beauvericin co-treated with enniatins] results in increased expression of SNRPD2 protein |
CTD |
PMID:32407736 |
|
NCBI chr 1:78,798,377...78,801,227
Ensembl chr 1:78,798,377...78,803,351
|
|
G |
Snrpd3 |
small nuclear ribonucleoprotein D3 polypeptide |
multiple interactions |
ISO |
[beauvericin co-treated with enniatins] results in decreased expression of SNRPD3 protein |
CTD |
PMID:32407736 |
|
NCBI chr20:13,130,112...13,145,947
Ensembl chr20:13,130,119...13,145,978
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G |
Src |
SRC proto-oncogene, non-receptor tyrosine kinase |
decreases activity |
EXP |
beauvericin results in decreased activity of SRC protein |
CTD |
PMID:25178661 |
|
NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476
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G |
Srm |
spermidine synthase |
decreases expression |
ISO |
beauvericin results in decreased expression of SRM mRNA |
CTD |
PMID:29203277 |
|
NCBI chr 5:159,025,919...159,029,076
Ensembl chr 5:159,025,873...159,029,405
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G |
Srsf7 |
serine and arginine rich splicing factor 7 |
multiple interactions |
ISO |
[beauvericin co-treated with enniatins] results in increased expression of SRSF7 protein |
CTD |
PMID:32407736 |
|
NCBI chr 6:14,811,775...14,818,968
Ensembl chr 6:14,811,808...14,818,965
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G |
Srxn1 |
sulfiredoxin 1 |
multiple interactions decreases expression |
ISO |
[beauvericin co-treated with enniatins co-treated with ochratoxin A] results in decreased expression of SRXN1 mRNA; [beauvericin co-treated with enniatins] results in decreased expression of SRXN1 mRNA; [Plant Extracts co-treated with beauvericin co-treated with enniatins] results in decreased expression of SRXN1 mRNA; [Plant Extracts co-treated with beauvericin] results in decreased expression of SRXN1 mRNA beauvericin results in decreased expression of SRXN1 mRNA |
CTD |
PMID:31100301 PMID:34015425 |
|
NCBI chr 3:140,604,490...140,610,050
Ensembl chr 3:140,599,608...140,628,448
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|
G |
Ssbp1 |
single stranded DNA binding protein 1 |
multiple interactions |
ISO |
[beauvericin co-treated with enniatins] results in decreased expression of SSBP1 protein |
CTD |
PMID:32407736 |
|
NCBI chr 4:69,266,024...69,276,135
Ensembl chr 4:69,266,102...69,276,135
|
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G |
Tbc1d2b |
TBC1 domain family, member 2B |
multiple interactions |
ISO |
[beauvericin co-treated with enniatins] results in decreased expression of TBC1D2B protein |
CTD |
PMID:32407736 |
|
NCBI chr 8:90,746,220...90,814,867
Ensembl chr 8:90,746,233...90,814,832
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G |
Tcn2 |
transcobalamin 2 |
multiple interactions |
ISO |
[beauvericin co-treated with enniatins] results in decreased expression of TCN2 protein |
CTD |
PMID:32407736 |
|
NCBI chr14:78,813,343...78,828,549
Ensembl chr14:78,813,343...78,828,489
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G |
Tcp11l1 |
t-complex 11 like 1 |
multiple interactions |
ISO |
[beauvericin co-treated with enniatins] results in decreased expression of TCP11L1 protein |
CTD |
PMID:32407736 |
|
NCBI chr 3:91,047,006...91,092,687
Ensembl chr 3:90,998,270...91,092,006
|
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G |
Tcp11l2 |
t-complex 11 like 2 |
multiple interactions |
ISO |
[beauvericin co-treated with enniatins] results in decreased expression of TCP11L2 protein |
CTD |
PMID:32407736 |
|
NCBI chr 7:19,150,241...19,185,135
Ensembl chr 7:19,150,252...19,185,095
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G |
Thyn1 |
thymocyte nuclear protein 1 |
multiple interactions |
ISO |
[beauvericin co-treated with enniatins] results in increased expression of THYN1 protein |
CTD |
PMID:32407736 |
|
NCBI chr 8:25,406,563...25,415,444
Ensembl chr 8:25,406,500...25,415,445
|
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G |
Timm9 |
translocase of inner mitochondrial membrane 9 |
multiple interactions |
ISO |
[beauvericin co-treated with enniatins] results in decreased expression of TIMM9 protein |
CTD |
PMID:32407736 |
|
NCBI chr 6:89,610,094...89,622,924
Ensembl chr 6:89,610,094...89,622,924
|
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G |
Tk1 |
thymidine kinase 1 |
multiple interactions |
ISO |
[beauvericin co-treated with enniatins] results in decreased expression of TK1 protein |
CTD |
PMID:32407736 |
|
NCBI chr10:103,034,755...103,046,125
Ensembl chr10:103,031,521...103,046,920
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|
G |
Tmem263 |
transmembrane protein 263 |
multiple interactions |
ISO |
[beauvericin co-treated with enniatins] results in increased expression of TMEM263 protein |
CTD |
PMID:32407736 |
|
NCBI chr 7:18,607,077...18,628,436
Ensembl chr 7:18,610,149...18,628,534
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G |
Tnfsf10 |
TNF superfamily member 10 |
decreases expression |
ISO |
beauvericin results in decreased expression of TNFSF10 mRNA |
CTD |
PMID:29203277 |
|
NCBI chr 2:110,199,835...110,227,239
Ensembl chr 2:110,207,916...110,225,135
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G |
Tomm22 |
translocase of outer mitochondrial membrane 22 |
multiple interactions |
ISO |
[beauvericin co-treated with enniatins] results in decreased expression of TOMM22 protein |
CTD |
PMID:32407736 |
|
NCBI chr 7:111,223,508...111,228,671
Ensembl chr 7:111,216,571...111,246,799
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G |
Tomm7 |
translocase of outer mitochondrial membrane 7 |
multiple interactions |
ISO |
[beauvericin co-treated with enniatins] results in decreased expression of TOMM7 protein |
CTD |
PMID:32407736 |
|
NCBI chr 4:11,305,122...11,311,963
Ensembl chr 4:11,305,110...11,311,962
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G |
Tuba1b |
tubulin, alpha 1B |
multiple interactions |
ISO |
[beauvericin co-treated with enniatins] results in increased expression of TUBA1B protein |
CTD |
PMID:32407736 |
|
NCBI chr 7:130,090,669...130,093,644
Ensembl chr 7:130,081,032...130,196,186
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G |
Tubb3 |
tubulin, beta 3 class III |
multiple interactions |
ISO |
[beauvericin co-treated with enniatins] results in increased expression of TUBB3 protein |
CTD |
PMID:32407736 |
|
NCBI chr19:51,457,187...51,466,243
Ensembl chr19:51,457,184...51,466,243
|
|
G |
Tubb4a |
tubulin, beta 4A class IVa |
multiple interactions |
ISO |
[beauvericin co-treated with enniatins] results in increased expression of TUBB4A protein |
CTD |
PMID:32407736 |
|
NCBI chr 9:1,917,841...1,925,286
Ensembl chr 9:1,917,845...1,925,291
|
|
G |
Tubb4b |
tubulin, beta 4B class IVb |
multiple interactions |
ISO |
[beauvericin co-treated with enniatins] results in increased expression of TUBB4B protein |
CTD |
PMID:32407736 |
|
NCBI chr 3:8,037,844...8,040,294
Ensembl chr 3:8,037,799...8,040,296
|
|
G |
Tubb5 |
tubulin, beta 5 class I |
multiple interactions |
ISO |
[beauvericin co-treated with enniatins] results in increased expression of TUBB protein |
CTD |
PMID:32407736 |
|
NCBI chr20:2,912,779...2,916,928
Ensembl chr20:2,912,778...2,916,940
|
|
G |
Txnip |
thioredoxin interacting protein |
increases expression multiple interactions decreases expression |
ISO |
beauvericin results in increased expression of TXNIP mRNA [beauvericin co-treated with enniatins co-treated with ochratoxin A] results in increased expression of TXNIP mRNA; [Plant Extracts co-treated with beauvericin co-treated with enniatins] results in increased expression of TXNIP mRNA; [Plant Extracts co-treated with beauvericin] results in increased expression of TXNIP mRNA beauvericin results in decreased expression of TXNIP mRNA |
CTD |
PMID:29203277 PMID:34015425 |
|
NCBI chr 2:184,093,079...184,096,882
Ensembl chr 2:184,092,991...184,096,886
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|
G |
Ucp2 |
uncoupling protein 2 |
multiple interactions decreases expression |
ISO |
[beauvericin co-treated with enniatins co-treated with ochratoxin A] results in increased expression of UCP2 mRNA; [beauvericin co-treated with enniatins] results in decreased expression of UCP2 mRNA; [Plant Extracts co-treated with beauvericin co-treated with enniatins] results in increased expression of UCP2 mRNA; [Plant Extracts co-treated with beauvericin] results in increased expression of UCP2 mRNA; [Plant Extracts co-treated with ochratoxin A co-treated with Zearalenone co-treated with beauvericin] results in decreased expression of UCP2 mRNA beauvericin results in decreased expression of UCP2 mRNA |
CTD |
PMID:31100301 PMID:34015425 |
|
NCBI chr 1:154,839,242...154,845,612
Ensembl chr 1:154,839,209...154,845,611
|
|
G |
Ucp3 |
uncoupling protein 3 |
multiple interactions |
ISO |
[beauvericin co-treated with enniatins] results in decreased expression of UCP3 mRNA |
CTD |
PMID:31100301 |
|
NCBI chr 1:154,815,777...154,828,764
Ensembl chr 1:154,815,777...154,828,762
|
|
G |
Ybx1 |
Y box binding protein 1 |
decreases expression |
ISO |
beauvericin results in decreased expression of YBX1 mRNA |
CTD |
PMID:29203277 |
|
NCBI chr 5:132,882,137...132,899,108
Ensembl chr 5:132,882,145...132,898,862
|
|
G |
Ybx3 |
Y box binding protein 3 |
decreases expression |
ISO |
beauvericin results in decreased expression of YBX3 mRNA |
CTD |
PMID:29203277 |
|
NCBI chr 4:165,129,747...165,153,101
Ensembl chr 4:165,129,758...165,153,161
|
|
G |
Ykt6 |
YKT6 v-SNARE homolog |
multiple interactions |
ISO |
[beauvericin co-treated with enniatins] results in increased expression of YKT6 protein |
CTD |
PMID:32407736 |
|
NCBI chr14:80,832,187...80,843,394
Ensembl chr14:80,832,187...80,843,385
|
|
|
G |
Agt |
angiotensinogen |
multiple interactions |
EXP |
[Egtazic Acid co-treated with Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone] inhibits the reaction [AGT protein results in increased abundance of Reactive Oxygen Species] |
CTD |
PMID:18854758 |
|
NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977
|
|
G |
Akt1 |
AKT serine/threonine kinase 1 |
increases phosphorylation |
ISO |
Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in increased phosphorylation of AKT1 protein |
CTD |
PMID:19901985 |
|
NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
|
|
G |
Aqp9 |
aquaporin 9 |
multiple interactions |
ISO |
Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone inhibits the reaction [AQP9 protein results in increased uptake of Lactic Acid]; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone inhibits the reaction [AQP9 protein results in increased uptake of Selenious Acid] |
CTD |
PMID:28798983 |
|
NCBI chr 8:71,797,231...71,837,485
Ensembl chr 8:71,797,234...71,837,395
|
|
G |
Bax |
BCL2 associated X, apoptosis regulator |
decreases expression |
ISO |
Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of BAX mRNA |
CTD |
PMID:16039398 |
|
NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
|
|
G |
Bcl2l1 |
Bcl2-like 1 |
decreases expression |
ISO |
Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of BCL2L1 mRNA |
CTD |
PMID:16039398 |
|
NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
|
|
G |
Casp3 |
caspase 3 |
increases activity |
ISO |
Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in increased activity of CASP3 protein |
CTD |
PMID:20683024 |
|
NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
|
|
G |
Casp8 |
caspase 8 |
decreases expression |
ISO |
Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of CASP8 mRNA |
CTD |
PMID:16039398 |
|
NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
|
|
G |
Cat |
catalase |
decreases expression |
ISO |
Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of CAT mRNA |
CTD |
PMID:16039398 |
|
NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
|
|
G |
Ccnc |
cyclin C |
decreases expression |
ISO |
Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of CCNC mRNA |
CTD |
PMID:16039398 |
|
NCBI chr 5:35,266,828...35,284,943
Ensembl chr 5:35,266,823...35,296,584
|
|
G |
Ccnd1 |
cyclin D1 |
decreases expression |
ISO |
Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of CCND1 mRNA |
CTD |
PMID:16039398 |
|
NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
|
|
G |
Ccng1 |
cyclin G1 |
decreases expression |
ISO |
Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of CCNG1 mRNA |
CTD |
PMID:16039398 |
|
NCBI chr10:25,176,231...25,182,604
Ensembl chr10:25,176,234...25,181,641
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|
G |
Cdk4 |
cyclin-dependent kinase 4 |
multiple interactions |
ISO |
Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone promotes the reaction [CDKN1B protein binds to CDK4 protein] |
CTD |
PMID:19819288 |
|
NCBI chr 7:62,885,647...62,889,562
Ensembl chr 7:62,883,105...62,942,403
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|
G |
Cdkn1b |
cyclin-dependent kinase inhibitor 1B |
multiple interactions increases expression |
ISO |
Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone promotes the reaction [CDKN1B protein binds to CDK4 protein] Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in increased expression of CDKN1B protein |
CTD |
PMID:19819288 |
|
NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982
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G |
Comt |
catechol-O-methyltransferase |
decreases activity multiple interactions |
ISO |
Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased activity of COMT protein [Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased activity of COMT protein] which results in decreased abundance of Adenosine Triphosphate |
CTD |
PMID:14975680 |
|
NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642
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G |
Coq10a |
coenzyme Q10A |
decreases expression |
ISO |
Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of COQ10A protein |
CTD |
PMID:21308897 |
|
NCBI chr 7:792,089...798,392
Ensembl chr 7:792,089...800,161
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G |
Coq2 |
coenzyme Q2, polyprenyltransferase |
increases expression |
ISO |
Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in increased expression of COQ2 mRNA |
CTD |
PMID:21308897 |
|
NCBI chr14:8,941,429...8,961,418
Ensembl chr14:8,941,461...8,960,891
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G |
Coq3 |
coenzyme Q3 methyltransferase |
decreases expression |
ISO |
Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of COQ3 mRNA |
CTD |
PMID:21308897 |
|
NCBI chr 5:35,429,567...35,460,613
Ensembl chr 5:35,429,574...35,460,607
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G |
Coq4 |
coenzyme Q4 |
increases expression |
ISO |
Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in increased expression of COQ4 mRNA |
CTD |
PMID:21308897 |
|
NCBI chr 3:13,060,054...13,070,502
Ensembl chr 3:13,060,455...13,068,799
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G |
Coq5 |
coenzyme Q5, methyltransferase |
increases expression |
ISO |
Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in increased expression of COQ5 mRNA |
CTD |
PMID:21308897 |
|
NCBI chr12:41,316,922...41,333,855
Ensembl chr12:41,316,748...41,333,848
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G |
Coq6 |
coenzyme Q6 monooxygenase |
increases expression |
ISO |
Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in increased expression of COQ6 mRNA |
CTD |
PMID:21308897 |
|
NCBI chr 6:104,007,814...104,019,888
Ensembl chr 6:104,007,872...104,024,657
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G |
Coq7 |
coenzyme Q7, hydroxylase |
increases expression |
ISO |
Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in increased expression of COQ7 mRNA |
CTD |
PMID:21308897 |
|
NCBI chr 1:172,836,359...172,851,173
Ensembl chr 1:172,835,188...172,851,158
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G |
Coq8a |
coenzyme Q8A |
increases expression |
ISO |
Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in increased expression of COQ8A mRNA |
CTD |
PMID:21308897 |
|
NCBI chr13:91,904,731...91,933,588
Ensembl chr13:91,904,739...91,931,431
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G |
Coq9 |
coenzyme Q9 |
increases expression |
ISO |
Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in increased expression of COQ9 mRNA |
CTD |
PMID:21308897 |
|
NCBI chr19:10,166,948...10,179,976
Ensembl chr19:10,166,951...10,179,949
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G |
Cyp1a1 |
cytochrome P450, family 1, subfamily a, polypeptide 1 |
increases expression |
ISO |
Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in increased expression of CYP1A1 mRNA |
CTD |
PMID:16039398 |
|
NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
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G |
Ddb1 |
damage-specific DNA binding protein 1 |
decreases expression |
ISO |
Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of DDB1 mRNA |
CTD |
PMID:16039398 |
|
NCBI chr 1:207,252,890...207,278,685
Ensembl chr 1:207,252,890...207,278,676
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G |
Dnaja1 |
DnaJ heat shock protein family (Hsp40) member A1 |
decreases expression |
ISO |
Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of DNAJA1 mRNA |
CTD |
PMID:16039398 |
|
NCBI chr 5:55,842,414...55,853,326
Ensembl chr 5:55,842,426...55,853,967
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G |
Egr1 |
early growth response 1 |
decreases expression |
ISO |
Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of EGR1 mRNA |
CTD |
PMID:16039398 |
|
NCBI chr18:26,463,333...26,465,531
Ensembl chr18:26,462,981...26,466,766
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G |
Ephx2 |
epoxide hydrolase 2 |
decreases expression |
ISO |
Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of EPHX2 mRNA |
CTD |
PMID:16039398 |
|
NCBI chr15:40,289,901...40,327,632
Ensembl chr15:40,289,902...40,327,615
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|
G |
Fmr1 |
fragile X messenger ribonucleoprotein 1 |
multiple interactions |
ISO |
Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone inhibits the reaction [FMR1 5' UTR mutant form results in increased abundance of Hydroxyl Radical]; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone inhibits the reaction [FMR1 5' UTR mutant form results in increased abundance of Superoxides] |
CTD |
PMID:27385396 |
|
NCBI chr X:147,240,239...147,278,057
Ensembl chr X:147,240,301...147,278,050
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|
G |
Gadd45a |
growth arrest and DNA-damage-inducible, alpha |
decreases expression |
ISO |
Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of GADD45A mRNA |
CTD |
PMID:16039398 |
|
NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115
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|
G |
Gdf15 |
growth differentiation factor 15 |
increases expression |
ISO |
Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in increased expression of GDF15 mRNA |
CTD |
PMID:16039398 |
|
NCBI chr16:18,805,312...18,807,893
Ensembl chr16:18,805,239...18,808,055
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G |
Gsr |
glutathione-disulfide reductase |
decreases expression |
ISO |
Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of GSR mRNA |
CTD |
PMID:16039398 |
|
NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
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G |
Gstm5 |
glutathione S-transferase, mu 5 |
decreases expression |
ISO |
Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of GSTM3 mRNA |
CTD |
PMID:16039398 |
|
NCBI chr 2:195,531,627...195,534,562
Ensembl chr 2:195,531,495...195,534,553
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G |
Hmox1 |
heme oxygenase 1 |
increases expression |
ISO |
Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in increased expression of HMOX1 mRNA |
CTD |
PMID:16039398 |
|
NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
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G |
Hmox2 |
heme oxygenase 2 |
decreases expression |
ISO |
Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of HMOX2 mRNA |
CTD |
PMID:16039398 |
|
NCBI chr10:10,797,076...10,831,178
Ensembl chr10:10,797,055...10,831,148
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G |
Hsf1 |
heat shock transcription factor 1 |
decreases expression |
ISO |
Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of HSF1 mRNA |
CTD |
PMID:16039398 |
|
NCBI chr 7:108,196,040...108,223,011
Ensembl chr 7:108,196,056...108,223,011
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G |
Hsp90aa1 |
heat shock protein 90 alpha family class A member 1 |
decreases expression |
ISO |
Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of HSP90AA1 mRNA |
CTD |
PMID:16039398 |
|
NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268
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G |
Hspa1a |
heat shock protein family A (Hsp70) member 1A |
decreases expression |
ISO |
Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of HSPA1B mRNA |
CTD |
PMID:16039398 |
|
NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240
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G |
Hspa1b |
heat shock protein family A (Hsp70) member 1B |
decreases expression |
ISO |
Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of HSPA1A mRNA |
CTD |
PMID:16039398 |
|
NCBI chr20:3,870,765...3,873,221
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G |
Hspa1l |
heat shock protein family A (Hsp70) member 1 like |
decreases expression |
ISO |
Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of HSPA1L mRNA |
CTD |
PMID:16039398 |
|
NCBI chr20:3,848,843...3,855,571
Ensembl chr20:3,848,843...3,855,571
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G |
Hspa2 |
heat shock protein family A (Hsp70) member 2 |
decreases expression |
ISO |
Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of HSPA2 mRNA |
CTD |
PMID:16039398 |
|
NCBI chr 6:95,128,504...95,131,281
Ensembl chr 6:95,128,350...95,131,287
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G |
Hspa4 |
heat shock protein family A (Hsp70) member 4 |
decreases expression |
ISO |
Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of HSPA4 mRNA |
CTD |
PMID:16039398 |
|
NCBI chr10:37,408,025...37,449,080
Ensembl chr10:37,408,025...37,449,001
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G |
Hspa8 |
heat shock protein family A (Hsp70) member 8 |
decreases expression |
ISO |
Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of HSPA8 mRNA |
CTD |
PMID:16039398 |
|
NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259
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G |
Hspe1 |
heat shock protein family E (Hsp10) member 1 |
increases expression |
ISO |
Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in increased expression of HSPE1 mRNA |
CTD |
PMID:16039398 |
|
NCBI chr 9:56,589,912...56,593,000
Ensembl chr 9:56,589,789...56,593,089
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G |
Icam1 |
intercellular adhesion molecule 1 |
decreases expression |
EXP |
Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of ICAM1 mRNA |
CTD |
PMID:17416599 |
|
NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
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G |
Il18 |
interleukin 18 |
decreases expression |
ISO |
Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of IL18 mRNA |
CTD |
PMID:16039398 |
|
NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887
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G |
Il1a |
interleukin 1 alpha |
decreases expression |
ISO |
Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of IL1A mRNA |
CTD |
PMID:16039398 |
|
NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
|
|
G |
Kcnj12 |
potassium inwardly-rectifying channel, subfamily J, member 12 |
multiple interactions |
ISO |
Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone inhibits the reaction [KCNJ12 protein results in increased transport of Potassium] |
CTD |
PMID:12118013 |
|
NCBI chr10:45,696,621...45,745,528
Ensembl chr10:45,696,849...45,745,492
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G |
Kcnj4 |
potassium inwardly-rectifying channel, subfamily J, member 4 |
multiple interactions |
ISO |
Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone inhibits the reaction [KCNJ4 protein results in increased transport of Potassium] |
CTD |
PMID:12118013 |
|
NCBI chr 7:111,047,097...111,074,151
Ensembl chr 7:111,047,094...111,074,151
|
|
G |
Mdm2 |
MDM2 proto-oncogene |
decreases expression |
ISO |
Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of MDM2 mRNA |
CTD |
PMID:16039398 |
|
NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915
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G |
Mt1 |
metallothionein 1 |
decreases expression |
ISO |
Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of MT1A mRNA |
CTD |
PMID:16039398 |
|
NCBI chr19:10,826,032...10,827,048
Ensembl chr19:10,826,032...10,827,049
|
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G |
Mt2A |
metallothionein 2A |
decreases expression |
ISO |
Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of MT2A mRNA |
CTD |
PMID:16039398 |
|
NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784
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G |
Nfkbia |
NFKB inhibitor alpha |
decreases expression |
ISO |
Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of NFKBIA mRNA |
CTD |
PMID:16039398 |
|
NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
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|
G |
Nipa1 |
NIPA magnesium transporter 1 |
decreases expression |
EXP |
Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of NIPA1 mRNA |
CTD |
PMID:27157538 |
|
NCBI chr 1:106,834,000...106,875,148
Ensembl chr 1:106,834,000...106,874,790
|
|
G |
Pdss1 |
decaprenyl diphosphate synthase subunit 1 |
decreases expression |
ISO |
Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of PDSS1 mRNA |
CTD |
PMID:21308897 |
|
NCBI chr17:85,059,953...85,098,739
Ensembl chr17:85,060,106...85,098,730
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|
G |
Pdss2 |
decaprenyl diphosphate synthase subunit 2 |
increases expression |
ISO |
Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in increased expression of PDSS2 mRNA |
CTD |
PMID:21308897 |
|
NCBI chr20:46,709,631...46,938,704
Ensembl chr20:46,709,649...46,938,708
|
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G |
Pink1 |
PTEN induced kinase 1 |
multiple interactions |
ISO |
PINK1 protein affects the reaction [Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone affects the localization of PRKN protein] |
CTD |
PMID:24879156 |
|
NCBI chr 5:150,530,523...150,542,635
Ensembl chr 5:150,530,523...150,542,635
|
|
G |
Plcg1 |
phospholipase C, gamma 1 |
increases phosphorylation |
ISO |
Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in increased phosphorylation of PLCG1 protein |
CTD |
PMID:19901985 |
|
NCBI chr 3:149,385,587...149,416,330
Ensembl chr 3:149,385,587...149,416,330
|
|
G |
Ppp1r15a |
protein phosphatase 1, regulatory subunit 15A |
multiple interactions |
ISO |
Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone promotes the reaction [TARDBP protein binds to PPP1R15A protein] |
CTD |
PMID:29109149 |
|
NCBI chr 1:96,000,053...96,003,128
Ensembl chr 1:96,000,058...96,003,171
|
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G |
Prkaa1 |
protein kinase AMP-activated catalytic subunit alpha 1 |
increases phosphorylation |
ISO |
Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in increased phosphorylation of PRKAA1 protein |
CTD |
PMID:19901985 |
|
NCBI chr 2:54,240,298...54,275,978
Ensembl chr 2:54,240,137...54,275,978
|
|
G |
Prkn |
parkin RBR E3 ubiquitin protein ligase |
multiple interactions affects localization |
ISO |
PINK1 protein affects the reaction [Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone affects the localization of PRKN protein] |
CTD |
PMID:24879156 |
|
NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555
|
|
G |
Ptgs2 |
prostaglandin-endoperoxide synthase 2 |
increases expression |
ISO |
Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in increased expression of PTGS2 mRNA |
CTD |
PMID:16039398 |
|
NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
|
|
G |
Rad23a |
RAD23 homolog A, nucleotide excision repair protein |
decreases expression |
ISO |
Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of RAD23A mRNA |
CTD |
PMID:16039398 |
|
NCBI chr19:23,313,563...23,320,702
Ensembl chr19:23,314,797...23,320,695
|
|
G |
Rpl13a |
ribosomal protein L13A |
decreases expression |
ISO |
Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of RPL13A mRNA |
CTD |
PMID:16039398 |
|
NCBI chr 1:95,609,374...95,612,557
Ensembl chr 1:95,609,370...95,620,463
|
|
G |
Serpine1 |
serpin family E member 1 |
decreases expression |
ISO |
Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of SERPINE1 mRNA |
CTD |
PMID:16039398 |
|
NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
|
|
G |
Slc18a2 |
solute carrier family 18 member A2 |
multiple interactions |
EXP |
Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone inhibits the reaction [SLC18A2 protein results in increased uptake of Serotonin] |
CTD |
PMID:1438304 |
|
NCBI chr 1:258,413,748...258,449,143
Ensembl chr 1:258,413,959...258,448,325
|
|
G |
Slc41a2 |
solute carrier family 41 member 2 |
increases expression |
EXP |
Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in increased expression of SLC41A2 mRNA |
CTD |
PMID:27157538 |
|
NCBI chr 7:20,383,714...20,491,178
Ensembl chr 7:20,383,757...20,491,166
|
|
G |
Sod2 |
superoxide dismutase 2 |
increases expression |
ISO |
Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in increased expression of SOD2 mRNA |
CTD |
PMID:16039398 |
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NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
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G |
Stat3 |
signal transducer and activator of transcription 3 |
affects response to substance |
ISO |
STAT3 protein affects the susceptibility to Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone |
CTD |
PMID:20224768 |
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NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
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G |
Tardbp |
TAR DNA binding protein |
multiple interactions |
ISO |
Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone promotes the reaction [TARDBP protein binds to PPP1R15A protein] |
CTD |
PMID:29109149 |
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NCBI chr 5:159,050,518...159,062,218
Ensembl chr 5:159,051,799...159,062,055
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G |
Xrcc5 |
X-ray repair cross complementing 5 |
decreases expression |
ISO |
Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of XRCC5 mRNA |
CTD |
PMID:16039398 |
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NCBI chr 9:73,955,220...74,044,020
Ensembl chr 9:73,955,216...74,044,018
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G |
Agt |
angiotensinogen |
multiple interactions |
EXP |
Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [Glucose results in increased expression of AGT mRNA]; Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [Glucose results in increased expression of AGT protein] |
CTD |
PMID:12130563 |
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NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977
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G |
Ambra1 |
autophagy and beclin 1 regulator 1 |
multiple interactions |
ISO |
Carbonyl Cyanide m-Chlorophenyl Hydrazone promotes the reaction [AMBRA1 protein binds to PRKN protein] |
CTD |
PMID:24879156 |
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NCBI chr 3:77,700,936...77,890,221
Ensembl chr 3:77,700,936...77,890,221
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G |
Atm |
ATM serine/threonine kinase |
multiple interactions increases phosphorylation |
ISO |
ATM protein affects the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone results in decreased expression of COX4 protein]; Carbonyl Cyanide m-Chlorophenyl Hydrazone promotes the reaction [PINK1 protein binds to ATM protein] Carbonyl Cyanide m-Chlorophenyl Hydrazone results in increased phosphorylation of ATM protein |
CTD |
PMID:29660402 |
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NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437
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G |
Becn1 |
beclin 1 |
multiple interactions |
ISO EXP |
Carbonyl Cyanide m-Chlorophenyl Hydrazone promotes the reaction [BECN1 protein binds to PRKN protein] BECN1 protein inhibits the reaction [BECN1 protein affects the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone affects the localization of PRKN protein]]; Carbonyl Cyanide m-Chlorophenyl Hydrazone promotes the reaction [BECN1 protein binds to PRKN protein] BECN1 protein affects the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone affects the localization of PINK1 protein]; BECN1 protein affects the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone affects the localization of PRKN protein]; BECN1 protein affects the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone results in decreased expression of and results in increased ubiquitination of MFN2 protein]; BECN1 protein affects the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone results in increased phosphorylation of PRKN protein]; Carbonyl Cyanide m-Chlorophenyl Hydrazone promotes the reaction [BECN1 protein binds to PRKN protein] |
CTD |
PMID:24879156 |
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NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742
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G |
Bnip3l |
BCL2 interacting protein 3 like |
increases phosphorylation multiple interactions |
ISO |
Carbonyl Cyanide m-Chlorophenyl Hydrazone results in increased phosphorylation of BNIP3L protein BNIP3L protein affects the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone results in decreased expression of COX4 protein]; BNIP3L protein affects the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone results in decreased expression of HSPD1 protein] |
CTD |
PMID:32142837 |
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NCBI chr15:41,174,594...41,197,730
Ensembl chr15:41,174,594...41,197,803
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G |
Canx |
calnexin |
affects localization |
ISO |
Carbonyl Cyanide m-Chlorophenyl Hydrazone affects the localization of CANX protein |
CTD |
PMID:28940366 |
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NCBI chr10:34,623,865...34,656,866
Ensembl chr10:34,625,191...34,656,821
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G |
Casp1 |
caspase 1 |
multiple interactions |
ISO |
Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide, E coli O55-B5] results in increased cleavage of CASP1 protein] |
CTD |
PMID:33524445 |
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NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383
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G |
Casp3 |
caspase 3 |
multiple interactions increases expression |
EXP ISO |
Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [Testosterone results in increased cleavage of CASP3 protein] DNM1L protein promotes the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone results in increased expression of CASP3 protein modified form]; PGAM5 protein promotes the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone results in increased expression of CASP3 protein modified form] |
CTD |
PMID:24658017 PMID:29241732 |
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NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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G |
Casp9 |
caspase 9 |
increases expression multiple interactions |
ISO |
Carbonyl Cyanide m-Chlorophenyl Hydrazone results in increased expression of CASP9 protein modified form DNM1L protein promotes the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone results in increased expression of CASP9 protein modified form] |
CTD |
PMID:29241732 |
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NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
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G |
Cirbp |
cold inducible RNA binding protein |
decreases expression |
ISO |
Carbonyl Cyanide m-Chlorophenyl Hydrazone results in decreased expression of CIRBP mRNA |
CTD |
PMID:15075239 |
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NCBI chr 7:9,533,857...9,538,899
Ensembl chr 7:9,424,178...9,538,818
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G |
Cox4i1 |
cytochrome c oxidase subunit 4i1 |
decreases expression |
ISO |
Carbonyl Cyanide m-Chlorophenyl Hydrazone results in decreased expression of COX4I1 protein |
CTD |
PMID:27318970 |
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NCBI chr19:48,721,680...48,727,920
Ensembl chr19:48,721,199...48,727,921
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G |
Ctsl |
cathepsin L |
increases expression |
ISO |
Carbonyl Cyanide m-Chlorophenyl Hydrazone results in increased expression of CTSL mRNA |
CTD |
PMID:15978749 |
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NCBI chr17:764,370...770,533
Ensembl chr17:764,309...770,548
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G |
Dnm1l |
dynamin 1-like |
multiple interactions decreases expression |
ISO |
DNM1L protein promotes the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone results in increased expression of CASP3 protein modified form]; DNM1L protein promotes the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone results in increased expression of CASP9 protein modified form] Carbonyl Cyanide m-Chlorophenyl Hydrazone results in decreased expression of DNM1L protein modified form |
CTD |
PMID:28940366 PMID:29241732 |
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NCBI chr11:84,581,216...84,632,382
Ensembl chr11:84,581,216...84,631,482
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G |
Faslg |
Fas ligand |
multiple interactions |
EXP |
Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [Testosterone results in increased expression of FASLG mRNA] |
CTD |
PMID:24658017 |
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NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215
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G |
Fkbp5 |
FKBP prolyl isomerase 5 |
multiple interactions |
ISO |
[Carbonyl Cyanide m-Chlorophenyl Hydrazone results in increased expression of and affects the localization of PINK1 protein] promotes the reaction [FKBP5 protein binds to PINK1 protein] |
CTD |
PMID:30734931 |
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NCBI chr20:6,457,207...6,575,404
Ensembl chr20:6,457,216...6,541,674
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G |
Fmc1 |
formation of mitochondrial complex V assembly factor 1 |
decreases expression multiple interactions |
ISO |
Carbonyl Cyanide m-Chlorophenyl Hydrazone results in decreased expression of FMC1 protein bafilomycin A1 inhibits the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone results in decreased expression of FMC1 protein] |
CTD |
PMID:29371327 |
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NCBI chr 4:67,274,104...67,282,140
Ensembl chr 4:67,274,104...67,282,140
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G |
Hk2 |
hexokinase 2 |
multiple interactions |
ISO |
Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of HK2 protein] |
CTD |
PMID:34481905 |
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NCBI chr 4:115,234,509...115,283,530
Ensembl chr 4:115,234,509...115,283,530
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G |
Hspd1 |
heat shock protein family D (Hsp60) member 1 |
decreases expression multiple interactions |
ISO |
Carbonyl Cyanide m-Chlorophenyl Hydrazone results in decreased expression of HSPD1 protein BNIP3L protein affects the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone results in decreased expression of HSPD1 protein] |
CTD |
PMID:32142837 |
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NCBI chr 9:56,579,195...56,590,011
Ensembl chr 9:56,579,201...56,589,662
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G |
Il1b |
interleukin 1 beta |
multiple interactions |
ISO |
Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of IL1B mRNA] |
CTD |
PMID:33524445 |
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NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
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G |
Keap1 |
Kelch-like ECH-associated protein 1 |
multiple interactions |
ISO |
[[Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [SQSTM1 protein binds to KEAP1 protein]] promotes the reaction [KEAP1 protein binds to NFE2L2 protein]] which results in decreased activity of NFE2L2 protein; [Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [SQSTM1 protein binds to KEAP1 protein]] promotes the reaction [KEAP1 protein binds to NFE2L2 protein]; Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [SQSTM1 protein binds to KEAP1 protein] |
CTD |
PMID:30715550 |
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NCBI chr 8:19,768,375...19,777,862
Ensembl chr 8:19,768,375...19,777,862
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G |
Ldha |
lactate dehydrogenase A |
multiple interactions |
ISO |
Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of LDHA protein] |
CTD |
PMID:34481905 |
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NCBI chr 1:97,371,823...97,381,247
Ensembl chr 1:97,366,021...97,433,472
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G |
Lep |
leptin |
multiple interactions decreases response to substance |
ISO |
Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [LEP protein results in increased chemical synthesis of Reactive Oxygen Species] Carbonyl Cyanide m-Chlorophenyl Hydrazone results in decreased susceptibility to LEP protein |
CTD |
PMID:11342529 |
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NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
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G |
Lonp1 |
lon peptidase 1, mitochondrial |
increases expression |
ISO |
Carbonyl Cyanide m-Chlorophenyl Hydrazone results in increased expression of LONP1 mRNA |
CTD |
PMID:28940366 |
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NCBI chr 9:1,447,444...1,459,771
Ensembl chr 9:1,447,447...1,459,771
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G |
Mapt |
microtubule-associated protein tau |
affects localization |
EXP |
Carbonyl Cyanide m-Chlorophenyl Hydrazone affects the localization of MAPT protein |
CTD |
PMID:17634376 |
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NCBI chr10:89,138,644...89,236,137
Ensembl chr10:89,138,627...89,236,129
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G |
Mfn2 |
mitofusin 2 |
multiple interactions |
EXP ISO |
BECN1 protein affects the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone results in decreased expression of and results in increased ubiquitination of MFN2 protein]; Carbonyl Cyanide m-Chlorophenyl Hydrazone results in decreased expression of and results in increased ubiquitination of MFN2 protein Carbonyl Cyanide m-Chlorophenyl Hydrazone results in decreased expression of and affects the localization of MFN2 protein |
CTD |
PMID:24879156 PMID:28940366 |
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NCBI chr 5:158,304,285...158,335,502
Ensembl chr 5:158,304,287...158,335,342
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G |
Mt-nd1 |
mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 1 |
decreases expression multiple interactions |
ISO |
Carbonyl Cyanide m-Chlorophenyl Hydrazone results in decreased expression of ND1 protein Deoxyglucose inhibits the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone results in decreased expression of ND1 protein] |
CTD |
PMID:34481905 |
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NCBI chr MT:2,740...3,694
Ensembl chr MT:2,740...3,694
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G |
Nfe2l2 |
NFE2 like bZIP transcription factor 2 |
multiple interactions |
ISO |
[[Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [SQSTM1 protein binds to KEAP1 protein]] promotes the reaction [KEAP1 protein binds to NFE2L2 protein]] which results in decreased activity of NFE2L2 protein; [Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [SQSTM1 protein binds to KEAP1 protein]] promotes the reaction [KEAP1 protein binds to NFE2L2 protein] |
CTD |
PMID:30715550 |
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NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737
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G |
Nfkb1 |
nuclear factor kappa B subunit 1 |
increases expression |
ISO |
Carbonyl Cyanide m-Chlorophenyl Hydrazone results in increased expression of NFKB1 protein |
CTD |
PMID:15978749 |
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NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
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G |
Nfkbib |
NFKB inhibitor beta |
decreases expression |
ISO |
Carbonyl Cyanide m-Chlorophenyl Hydrazone results in decreased expression of NFKBIB protein |
CTD |
PMID:15978749 |
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NCBI chr 1:84,046,292...84,053,862
Ensembl chr 1:84,046,295...84,053,862
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G |
Nlrp3 |
NLR family, pyrin domain containing 3 |
multiple interactions |
ISO |
Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of NLRP3 protein] |
CTD |
PMID:33524445 |
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NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811
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G |
Opa1 |
OPA1, mitochondrial dynamin like GTPase |
decreases expression |
ISO |
Carbonyl Cyanide m-Chlorophenyl Hydrazone results in decreased expression of OPA1 protein alternative form |
CTD |
PMID:28940366 |
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NCBI chr11:71,108,100...71,185,170
Ensembl chr11:71,109,873...71,185,109
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G |
Park7 |
Parkinsonism associated deglycase |
multiple interactions |
ISO |
PARK7 gene mutant form promotes the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone affects the localization of PRKN protein] |
CTD |
PMID:22872702 |
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NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970
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G |
Pgam5 |
PGAM family member 5, mitochondrial serine/threonine protein phosphatase |
multiple interactions |
ISO |
PGAM5 protein promotes the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone results in increased expression of CASP3 protein modified form] |
CTD |
PMID:29241732 |
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NCBI chr12:46,409,324...46,416,410
Ensembl chr12:46,409,369...46,416,420
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G |
Pik3c3 |
phosphatidylinositol 3-kinase, catalytic subunit type 3 |
multiple interactions |
ISO |
Carbonyl Cyanide m-Chlorophenyl Hydrazone promotes the reaction [PIK3C3 protein binds to PRKN protein] |
CTD |
PMID:24879156 |
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NCBI chr18:21,845,282...21,934,387
Ensembl chr18:21,845,295...21,929,048
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G |
Pink1 |
PTEN induced kinase 1 |
multiple interactions affects localization increases expression increases stability |
ISO EXP |
PINK1 gene mutant form inhibits the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone affects the localization of PRKN protein] BECN1 protein affects the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone affects the localization of PINK1 protein]; PINK1 protein affects the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone affects the localization of PRKN protein] [Carbonyl Cyanide m-Chlorophenyl Hydrazone co-treated with PRKN protein] results in increased expression of PINK1 protein; [Carbonyl Cyanide m-Chlorophenyl Hydrazone results in increased expression of and affects the localization of PINK1 protein] promotes the reaction [FKBP5 protein binds to PINK1 protein]; Carbonyl Cyanide m-Chlorophenyl Hydrazone promotes the reaction [PINK1 protein binds to ATM protein]; Carbonyl Cyanide m-Chlorophenyl Hydrazone results in increased expression of and affects the localization of PINK1 protein; Carbonyl Cyanide m-Chlorophenyl Hydrazone results in increased expression of and results in increased phosphorylation of PINK1 protein Carbonyl Cyanide m-Chlorophenyl Hydrazone results in increased expression of PINK1 protein Carbonyl Cyanide m-Chlorophenyl Hydrazone results in increased stability of PINK1 protein |
CTD |
PMID:22872702 PMID:24879156 PMID:26070385 PMID:27318970 PMID:28673964 PMID:29371327 PMID:29660402 PMID:30734931 More...
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NCBI chr 5:150,530,523...150,542,635
Ensembl chr 5:150,530,523...150,542,635
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G |
Pkm |
pyruvate kinase M1/2 |
multiple interactions |
ISO |
Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of PKM protein] |
CTD |
PMID:34481905 |
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NCBI chr 8:60,057,629...60,079,600
Ensembl chr 8:60,057,402...60,079,599
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G |
Prkn |
parkin RBR E3 ubiquitin protein ligase |
affects localization increases response to substance decreases response to substance affects expression decreases expression increases phosphorylation multiple interactions |
ISO EXP |
Carbonyl Cyanide m-Chlorophenyl Hydrazone affects the localization of PRKN protein PRKN gene mutant form results in increased susceptibility to Carbonyl Cyanide m-Chlorophenyl Hydrazone PRKN protein results in decreased susceptibility to Carbonyl Cyanide m-Chlorophenyl Hydrazone Carbonyl Cyanide m-Chlorophenyl Hydrazone affects the expression of PRKN protein alternative form Carbonyl Cyanide m-Chlorophenyl Hydrazone results in decreased expression of PRKN protein Carbonyl Cyanide m-Chlorophenyl Hydrazone results in increased phosphorylation of PRKN protein 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt inhibits the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone affects the localization of PRKN protein]; Acetylcysteine inhibits the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone affects the localization of PRKN protein]; Carbonyl Cyanide m-Chlorophenyl Hydrazone promotes the reaction [BECN1 protein binds to PRKN protein]; PARK7 gene mutant form promotes the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone affects the localization of PRKN protein]; PINK1 gene mutant form inhibits the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone affects the localization of PRKN protein] BECN1 protein affects the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone affects the localization of PRKN protein]; BECN1 protein affects the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone results in increased phosphorylation of PRKN protein]; Carbonyl Cyanide m-Chlorophenyl Hydrazone promotes the reaction [BECN1 protein binds to PRKN protein]; PINK1 protein affects the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone affects the localization of PRKN protein] [Carbonyl Cyanide m-Chlorophenyl Hydrazone co-treated with PRKN protein] results in increased expression of PINK1 protein; BECN1 protein inhibits the reaction [BECN1 protein affects the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone affects the localization of PRKN protein]]; Carbonyl Cyanide m-Chlorophenyl Hydrazone promotes the reaction [AMBRA1 protein binds to PRKN protein]; Carbonyl Cyanide m-Chlorophenyl Hydrazone promotes the reaction [BECN1 protein binds to PRKN protein]; Carbonyl Cyanide m-Chlorophenyl Hydrazone promotes the reaction [PIK3C3 protein binds to PRKN protein]; Tretinoin affects the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone affects the expression of PRKN protein alternative form] |
CTD |
PMID:16517603 PMID:22872702 PMID:24879156 PMID:26070385 PMID:28673964 PMID:28688199 PMID:29660402 More...
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NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555
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G |
Ptgs2 |
prostaglandin-endoperoxide synthase 2 |
multiple interactions |
ISO |
Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [Sodium Chloride results in increased expression of PTGS2 protein] Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [Glucose results in increased expression of PTGS2 mRNA]; Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [Glucose results in increased expression of PTGS2 protein] |
CTD |
PMID:14514642 PMID:16024921 |
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NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
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G |
Rbm3 |
RNA binding motif protein 3 |
decreases expression |
ISO |
Carbonyl Cyanide m-Chlorophenyl Hydrazone results in decreased expression of RBM3 mRNA |
CTD |
PMID:15075239 |
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NCBI chr X:14,348,909...14,352,387
Ensembl chr X:14,348,910...14,353,580
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G |
Rel |
REL proto-oncogene, NF-kB subunit |
increases expression |
ISO |
Carbonyl Cyanide m-Chlorophenyl Hydrazone results in increased expression of REL protein |
CTD |
PMID:15978749 |
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NCBI chr14:97,690,105...97,721,194
Ensembl chr14:97,695,161...97,720,892
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G |
Rela |
RELA proto-oncogene, NF-kB subunit |
multiple interactions |
ISO |
[Carbonyl Cyanide m-Chlorophenyl Hydrazone co-treated with Adenosine Triphosphate co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of RELA protein; Carbonyl Cyanide m-Chlorophenyl Hydrazone affects the reaction [lipopolysaccharide, E coli O55-B5 affects the localization of RELA protein]; Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide, E coli O55-B5] results in increased phosphorylation of RELA protein] |
CTD |
PMID:33524445 |
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NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
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G |
Slc2a1 |
solute carrier family 2 member 1 |
multiple interactions |
ISO |
Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of SLC2A1 protein] |
CTD |
PMID:34481905 |
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NCBI chr 5:132,717,196...132,745,416
Ensembl chr 5:132,717,196...132,745,416
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G |
Sqstm1 |
sequestosome 1 |
multiple interactions |
ISO |
[[Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [SQSTM1 protein binds to KEAP1 protein]] promotes the reaction [KEAP1 protein binds to NFE2L2 protein]] which results in decreased activity of NFE2L2 protein; [Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [SQSTM1 protein binds to KEAP1 protein]] promotes the reaction [KEAP1 protein binds to NFE2L2 protein]; Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of SQSTM1 protein]; Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [SQSTM1 protein binds to KEAP1 protein] |
CTD |
PMID:30715550 PMID:34481905 |
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NCBI chr10:34,525,517...34,536,685
Ensembl chr10:34,525,519...34,536,673
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G |
Timm23 |
translocase of inner mitochondrial membrane 23 |
decreases expression |
ISO |
Carbonyl Cyanide m-Chlorophenyl Hydrazone results in decreased expression of TIMM23 protein |
CTD |
PMID:29371327 |
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NCBI chr16:7,410,308...7,436,392
Ensembl chr16:7,409,688...7,436,379
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G |
Tnf |
tumor necrosis factor |
multiple interactions |
EXP ISO |
Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [Testosterone results in increased expression of TNF mRNA] Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of TNF mRNA] |
CTD |
PMID:24658017 PMID:33524445 |
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NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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G |
Cat |
catalase |
decreases activity |
ISO |
Chlortetracycline results in decreased activity of CAT protein |
CTD |
PMID:30768968 |
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NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
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G |
Gstp1 |
glutathione S-transferase pi 1 |
multiple interactions |
ISO |
Chlortetracycline inhibits the reaction [GSTP1 protein results in increased metabolism of 1-chloro-2,4-dinitrobenzene-glutathione conjugate] |
CTD |
PMID:23769903 |
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NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
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G |
Aco1 |
aconitase 1 |
increases activity increases expression multiple interactions |
EXP ISO |
Deferoxamine results in increased activity of ACO1 protein Deferoxamine results in increased expression of ACO1 protein [Deferoxamine results in decreased abundance of Iron] which results in increased activity of ACO1 protein |
CTD |
PMID:10397746 PMID:11054110 PMID:15893546 PMID:16568477 PMID:18073202 PMID:25106854 More...
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NCBI chr 5:55,259,841...55,315,872
Ensembl chr 5:55,259,827...55,316,391
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G |
Aco2 |
aconitase 2 |
decreases expression |
EXP |
Deferoxamine results in decreased expression of ACO2 protein |
CTD |
PMID:16568477 PMID:17469137 |
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NCBI chr 7:113,385,677...113,428,794
Ensembl chr 7:113,385,646...113,428,261
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G |
Acp5 |
acid phosphatase 5, tartrate resistant |
decreases activity multiple interactions |
ISO |
Deferoxamine results in decreased activity of ACP5 protein Deferoxamine inhibits the reaction [TF protein results in increased activity of ACP5 protein]; TF protein inhibits the reaction [Deferoxamine results in decreased activity of ACP5 protein] |
CTD |
PMID:31238089 |
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NCBI chr 8:20,663,984...20,670,604
Ensembl chr 8:20,663,985...20,667,929
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G |
Acta2 |
actin alpha 2, smooth muscle |
decreases expression increases expression multiple interactions |
EXP ISO |
Deferoxamine results in decreased expression of ACTA2 protein Deferoxamine results in increased expression of ACTA2 mRNA Deferoxamine inhibits the reaction [Artesunate results in decreased expression of ACTA2 mRNA] |
CTD |
PMID:18032466 PMID:30551460 |
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NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554
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G |
Adm |
adrenomedullin |
increases expression |
ISO |
Deferoxamine results in increased expression of ADM mRNA |
CTD |
PMID:11754965 |
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NCBI chr 1:164,745,484...164,747,655
Ensembl chr 1:164,745,466...164,747,654
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G |
Akt1 |
AKT serine/threonine kinase 1 |
multiple interactions |
EXP ISO |
Deferoxamine inhibits the reaction [PDGFB protein results in increased phosphorylation of AKT1 protein] [Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of AKT1 mRNA; MIR184 mRNA inhibits the reaction [[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of AKT1 mRNA] |
CTD |
PMID:18032466 PMID:35690295 |
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NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
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G |
Aldh3a1 |
aldehyde dehydrogenase 3 family, member A1 |
decreases expression multiple interactions |
ISO |
Deferoxamine results in decreased expression of ALDH3A1 mRNA Deferoxamine inhibits the reaction [Benzo(a)pyrene results in increased expression of ALDH3A1 mRNA] |
CTD |
PMID:14645679 |
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NCBI chr10:45,892,993...45,902,680
Ensembl chr10:45,892,924...45,902,681
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G |
Alpl |
alkaline phosphatase, biomineralization associated |
decreases expression multiple interactions |
ISO |
Deferoxamine results in decreased expression of ALPL mRNA Indomethacin promotes the reaction [Deferoxamine results in decreased expression of ALPL protein]; Sulindac promotes the reaction [Deferoxamine results in decreased expression of ALPL protein] |
CTD |
PMID:16772336 PMID:21882223 |
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NCBI chr 5:149,951,397...150,006,424
Ensembl chr 5:149,951,409...150,006,446
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G |
Anxa3 |
annexin A3 |
multiple interactions decreases expression |
ISO |
ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of ANXA3 protein] Deferoxamine results in decreased expression of ANXA3 protein |
CTD |
PMID:19515424 |
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NCBI chr14:12,727,708...12,781,717
Ensembl chr14:12,719,795...12,781,617
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G |
Apaf1 |
apoptotic peptidase activating factor 1 |
multiple interactions |
ISO |
[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of APAF1 mRNA; [Glucose co-treated with Deferoxamine] results in increased expression of APAF1 mRNA; Antineoplastic Agents, Immunological inhibits the reaction [[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of APAF1 mRNA]; Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of APAF1 mRNA]; MIR184 mRNA inhibits the reaction [[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of APAF1 mRNA] |
CTD |
PMID:33962019 PMID:35690295 |
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NCBI chr 7:25,494,143...25,579,540
Ensembl chr 7:25,494,609...25,579,540
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G |
App |
amyloid beta precursor protein |
affects binding multiple interactions |
ISO |
Deferoxamine binds to APP 5' UTR [Deferoxamine binds to APP 5' UTR] which results in decreased expression of APP protein; [Deferoxamine binds to APP 5' UTR] which results in decreased secretion of APP protein modified form; Deferoxamine inhibits the reaction [[[[APP protein modified form binds to Copper] which co-treated with Ascorbic Acid] results in increased oxidation of phosphatidylcholine hydroperoxide] which results in increased chemical synthesis of 4-hydroxy-2-nonenal] |
CTD |
PMID:15681799 PMID:17964426 |
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NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
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G |
Aqp4 |
aquaporin 4 |
multiple interactions |
EXP |
Deferoxamine inhibits the reaction [manganese(III) acetate dihydrate results in increased expression of AQP4 protein] |
CTD |
PMID:20648640 |
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NCBI chr18:6,507,903...6,524,558
Ensembl chr18:6,507,903...6,524,856
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G |
Arhgdia |
Rho GDP dissociation inhibitor alpha |
decreases expression multiple interactions |
ISO |
Deferoxamine results in decreased expression of ARHGDIA protein ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of ARHGDIA protein] |
CTD |
PMID:19515424 |
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NCBI chr10:105,854,526...105,858,020
Ensembl chr10:105,854,533...105,858,023
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G |
Arnt |
aryl hydrocarbon receptor nuclear translocator |
increases activity multiple interactions increases expression |
EXP ISO |
Deferoxamine results in increased activity of ARNT protein [Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of ARNT mRNA; [Glucose co-treated with Deferoxamine] results in increased expression of ARNT mRNA; Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of ARNT mRNA]; MIR184 mRNA inhibits the reaction [[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of ARNT mRNA] Deferoxamine results in increased expression of ARNT mRNA |
CTD |
PMID:10559391 PMID:33962019 PMID:35690295 |
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NCBI chr 2:182,997,731...183,056,584
Ensembl chr 2:182,997,736...183,056,580
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G |
Ash2l |
ASH2 like histone lysine methyltransferase complex subunit |
increases expression affects expression |
ISO |
Deferoxamine results in increased expression of ASH2L mRNA Deferoxamine affects the expression of ASH2L mRNA |
CTD |
PMID:23483119 |
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NCBI chr16:66,242,205...66,264,064
Ensembl chr16:66,242,212...66,264,061
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G |
Atf1 |
activating transcription factor 1 |
increases activity |
EXP |
Deferoxamine results in increased activity of ATF1 protein |
CTD |
PMID:10559391 |
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NCBI chr 7:131,361,962...131,404,677
Ensembl chr 7:131,362,450...131,404,670
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G |
Atm |
ATM serine/threonine kinase |
multiple interactions |
ISO |
Deferoxamine results in increased phosphorylation of and results in increased activity of ATM protein |
CTD |
PMID:16959548 |
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NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437
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G |
Atp6v0d2 |
ATPase H+ transporting V0 subunit D2 |
multiple interactions affects expression |
ISO |
Deferoxamine affects the reaction [TF protein affects the expression of ATP6V0D2 mRNA]; TF protein affects the reaction [Deferoxamine affects the expression of ATP6V0D2 mRNA] |
CTD |
PMID:31238089 |
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NCBI chr 5:33,336,257...33,385,354
Ensembl chr 5:33,336,264...33,385,354
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G |
Atp7a |
ATPase copper transporting alpha |
increases expression multiple interactions |
EXP |
Deferoxamine results in increased expression of ATP7A mRNA cupric chloride promotes the reaction [Deferoxamine results in increased expression of ATP7A mRNA]; Deferoxamine promotes the reaction [cupric chloride results in increased expression of ATP7A protein] |
CTD |
PMID:23174565 |
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NCBI chr X:71,094,144...71,201,550
Ensembl chr X:71,094,202...71,198,354
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G |
Bak1 |
BCL2-antagonist/killer 1 |
multiple interactions |
ISO |
[Glucose co-treated with Deferoxamine] results in increased expression of BAK1 mRNA; Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of BAK1 mRNA] |
CTD |
PMID:33962019 |
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NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264
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G |
Bax |
BCL2 associated X, apoptosis regulator |
increases expression multiple interactions |
ISO |
Deferoxamine results in increased expression of BAX mRNA; Deferoxamine results in increased expression of BAX protein [Cisplatin co-treated with Deferoxamine] results in increased expression of BAX protein; [Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of BAX mRNA; [Glucose co-treated with Deferoxamine] results in increased expression of BAX mRNA; [Glucose co-treated with Deferoxamine] results in increased expression of BAX protein; Antineoplastic Agents, Immunological inhibits the reaction [[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of BAX mRNA]; Deferoxamine inhibits the reaction [Hydrogen Peroxide affects the localization of BAX protein]; Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of BAX mRNA]; Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of BAX protein]; MIR184 mRNA inhibits the reaction [[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of BAX mRNA]; TP53 protein affects the reaction [Deferoxamine results in increased expression of BAX protein] |
CTD |
PMID:16800926 PMID:21742779 PMID:33962019 PMID:34126102 PMID:35690295 |
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NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
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G |
Bbc3 |
Bcl-2 binding component 3 |
increases expression multiple interactions |
ISO |
Deferoxamine results in increased expression of BBC3 mRNA [Glucose co-treated with Deferoxamine] results in increased expression of BBC3 mRNA; Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of BBC3 mRNA] |
CTD |
PMID:33962019 |
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NCBI chr 1:77,013,281...77,022,509
Ensembl chr 1:77,014,543...77,022,509
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G |
Bcl2 |
BCL2, apoptosis regulator |
multiple interactions decreases expression |
EXP ISO |
Deferoxamine inhibits the reaction [Copper Sulfate results in decreased expression of BCL2 mRNA] Deferoxamine results in decreased expression of BCL2 mRNA [Deferoxamine co-treated with tert-Butylhydroperoxide] results in decreased expression of BCL2 mRNA; [Glucose co-treated with Deferoxamine] results in decreased expression of BCL2 mRNA; [Glucose co-treated with Deferoxamine] results in decreased expression of BCL2 protein; Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in decreased expression of BCL2 mRNA]; Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in decreased expression of BCL2 protein]; MIR184 mRNA inhibits the reaction [[Deferoxamine co-treated with tert-Butylhydroperoxide] results in decreased expression of BCL2 mRNA] |
CTD |
PMID:30431687 PMID:33962019 PMID:35690295 |
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NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
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G |
Bcl2l15 |
Bcl2-like 15 |
increases expression multiple interactions |
ISO |
Deferoxamine results in increased expression of BCL2L15 mRNA [Glucose co-treated with Deferoxamine] results in increased expression of BCL2L15 mRNA; Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of BCL2L15 mRNA] |
CTD |
PMID:33962019 |
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NCBI chr 2:191,338,959...191,344,078
Ensembl chr 2:191,338,959...191,344,078
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G |
Becn1 |
beclin 1 |
multiple interactions |
ISO |
Deferoxamine inhibits the reaction [di-n-propyldithiocarbamate results in increased expression of BECN1 protein]; Deferoxamine inhibits the reaction [Hydrogen Peroxide affects the localization of BECN1 protein] |
CTD |
PMID:21742779 PMID:32687844 |
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NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742
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G |
Bid |
BH3 interacting domain death agonist |
multiple interactions |
ISO |
[Glucose co-treated with Deferoxamine] results in increased expression of BID mRNA; Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of BID mRNA] |
CTD |
PMID:33962019 |
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NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720
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G |
Bmp6 |
bone morphogenetic protein 6 |
multiple interactions decreases expression |
ISO |
Deferoxamine inhibits the reaction [BMP6 protein results in increased expression of HAMP mRNA]; ferric ammonium citrate affects the reaction [Deferoxamine inhibits the reaction [BMP6 protein results in increased expression of HAMP mRNA]] Deferoxamine results in decreased expression of BMP6 mRNA |
CTD |
PMID:25633564 PMID:32816093 |
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NCBI chr17:26,318,121...26,469,034
Ensembl chr17:26,318,569...26,470,365
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G |
Bnip3 |
BCL2 interacting protein 3 |
increases expression multiple interactions |
ISO |
Deferoxamine results in increased expression of BNIP3 mRNA [Glucose co-treated with Deferoxamine] results in increased expression of BNIP3 mRNA; Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of BNIP3 mRNA] |
CTD |
PMID:33962019 |
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NCBI chr 1:193,708,164...193,725,348
Ensembl chr 1:193,708,167...193,725,359
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G |
Bnip3l |
BCL2 interacting protein 3 like |
increases expression multiple interactions |
ISO |
Deferoxamine results in increased expression of BNIP3L mRNA [Glucose co-treated with Deferoxamine] results in increased expression of BNIP3L mRNA; Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of BNIP3L mRNA] |
CTD |
PMID:11832486 PMID:33962019 |
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NCBI chr15:41,174,594...41,197,730
Ensembl chr15:41,174,594...41,197,803
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G |
C5 |
complement C5 |
multiple interactions |
ISO |
Deferoxamine inhibits the reaction [Asbestos, Crocidolite results in increased cleavage of C5 protein]; Deferoxamine inhibits the reaction [Asbestos, Serpentine results in increased cleavage of C5 protein] |
CTD |
PMID:10777245 |
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NCBI chr 3:18,270,696...18,361,994
Ensembl chr 3:18,270,696...18,361,994
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G |
Cacna1h |
calcium voltage-gated channel subunit alpha1 H |
increases expression |
EXP |
Deferoxamine results in increased expression of CACNA1H mRNA |
CTD |
PMID:12679337 |
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NCBI chr10:14,390,104...14,448,204
Ensembl chr10:14,390,113...14,448,376
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G |
Car2 |
carbonic anhydrase 2 |
decreases expression |
ISO |
Deferoxamine results in decreased expression of CAR2 mRNA |
CTD |
PMID:31238089 |
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NCBI chr 2:86,741,625...86,756,766
Ensembl chr 2:86,741,626...86,756,818
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G |
Car9 |
carbonic anhydrase 9 |
increases expression |
ISO |
Deferoxamine results in increased expression of CA9 mRNA |
CTD |
PMID:25351418 |
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NCBI chr 5:57,763,234...57,769,838
Ensembl chr 5:57,763,206...57,769,838
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G |
Casp12 |
caspase 12 |
multiple interactions |
ISO |
Deferoxamine promotes the reaction [manganese chloride results in increased cleavage of and results in increased activity of CASP12 protein] |
CTD |
PMID:23764342 |
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NCBI chr 8:2,642,296...2,669,549
Ensembl chr 8:2,642,434...2,674,037
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G |
Casp3 |
caspase 3 |
increases expression multiple interactions increases activity |
ISO EXP |
Deferoxamine results in increased expression of CASP3 protein Deferoxamine inhibits the reaction [ferric ammonium citrate results in increased cleavage of CASP3 protein] Deferoxamine results in increased activity of CASP3 protein [Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of CASP3 mRNA; [Glucose co-treated with Deferoxamine] results in increased expression of CASP3 mRNA; [Glucose co-treated with Deferoxamine] results in increased expression of CASP3 protein; [Glucose co-treated with Deferoxamine] results in increased expression of CASP3 protein modified form; Antineoplastic Agents, Immunological inhibits the reaction [[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of CASP3 mRNA]; Deferoxamine inhibits the reaction [Cisplatin results in increased cleavage of CASP3 protein]; Deferoxamine inhibits the reaction [Doxorubicin results in increased cleavage of CASP3 protein]; Deferoxamine promotes the reaction [manganese chloride results in increased activity of CASP3 protein]; Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of CASP3 mRNA]; Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of CASP3 protein modified form]; Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of CASP3 protein]; MIR184 mRNA inhibits the reaction [[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of CASP3 mRNA]; Nitroprusside inhibits the reaction [Deferoxamine results in increased activity of CASP3 protein]; Vanadates inhibits the reaction [Deferoxamine results in increased activity of CASP3 protein] Deferoxamine inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased activity of CASP3 protein]; Deferoxamine inhibits the reaction [Copper Sulfate results in increased secretion of CASP3 protein]; Deferoxamine inhibits the reaction [Manganese results in increased activity of CASP3 protein] |
CTD |
PMID:11933051 PMID:12523938 PMID:16374551 PMID:16800926 PMID:23764342 PMID:26318285 PMID:30431687 PMID:33962019 PMID:34126102 PMID:35690295 More...
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NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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G |
Casp8 |
caspase 8 |
increases activity multiple interactions |
ISO |
Deferoxamine results in increased activity of CASP8 protein [Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of CASP8 mRNA; [Glucose co-treated with Deferoxamine] results in increased expression of CASP8 mRNA; Antineoplastic Agents, Immunological inhibits the reaction [[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of CASP8 mRNA]; Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of CASP8 mRNA]; MIR184 mRNA inhibits the reaction [[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of CASP8 mRNA]; Nitroprusside inhibits the reaction [Deferoxamine results in increased activity of CASP8 protein]; Vanadates inhibits the reaction [Deferoxamine results in increased activity of CASP8 protein] |
CTD |
PMID:16374551 PMID:33962019 PMID:35690295 |
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NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
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G |
Casp9 |
caspase 9 |
multiple interactions |
ISO |
Deferoxamine inhibits the reaction [Asbestos, Amosite results in increased activity of CASP9 protein] |
CTD |
PMID:12540492 PMID:14766669 |
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NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
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G |
Cat |
catalase |
multiple interactions |
EXP ISO |
Deferoxamine inhibits the reaction [Potassium Dichromate results in decreased activity of CAT protein] [Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of CAT mRNA |
CTD |
PMID:22115772 PMID:35690295 |
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NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
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G |
Cav1 |
caveolin 1 |
increases expression |
ISO |
Deferoxamine results in increased expression of CAV1 protein |
CTD |
PMID:16927372 |
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NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705
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G |
Ccl2 |
C-C motif chemokine ligand 2 |
multiple interactions |
EXP |
Deferoxamine inhibits the reaction [[Lipopolysaccharides co-treated with Fructose co-treated with Copper deficiency] results in increased expression of CCL2 protein] |
CTD |
PMID:25813056 |
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NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
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G |
Ccna2 |
cyclin A2 |
decreases expression |
ISO |
Deferoxamine results in decreased expression of CCNA2 protein |
CTD |
PMID:11468187 |
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NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577
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G |
Ccnb1 |
cyclin B1 |
decreases expression |
ISO |
Deferoxamine results in decreased expression of CCNB1 protein |
CTD |
PMID:11468187 |
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NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172
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G |
Ccnd1 |
cyclin D1 |
decreases expression |
ISO |
Deferoxamine results in decreased expression of CCND1 protein |
CTD |
PMID:11468187 |
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NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
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G |
Ccnd2 |
cyclin D2 |
decreases expression |
ISO |
Deferoxamine results in decreased expression of CCND2 protein |
CTD |
PMID:11468187 |
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NCBI chr 4:159,966,883...159,989,261
Ensembl chr 4:159,962,363...159,989,495
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G |
Ccnd3 |
cyclin D3 |
decreases expression |
ISO |
Deferoxamine results in decreased expression of CCND3 protein |
CTD |
PMID:11468187 |
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NCBI chr 9:13,394,161...13,400,341
Ensembl chr 9:13,394,169...13,489,371
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G |
Ccne1 |
cyclin E1 |
increases expression |
ISO |
Deferoxamine results in increased expression of CCNE1 protein |
CTD |
PMID:11468187 |
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NCBI chr 1:90,781,947...90,791,188
Ensembl chr 1:90,781,949...90,791,101
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G |
Cd36 |
CD36 molecule |
decreases expression |
ISO |
Deferoxamine results in decreased expression of CD36 protein |
CTD |
PMID:24170104 |
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NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903
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G |
Cdc14a |
cell division cycle 14A |
increases expression |
ISO |
Deferoxamine results in increased expression of CDC14A mRNA alternative form |
CTD |
PMID:16760464 |
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NCBI chr 2:204,225,540...204,380,927
Ensembl chr 2:204,225,540...204,380,927
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G |
Cdk2 |
cyclin dependent kinase 2 |
decreases activity decreases expression |
ISO |
Deferoxamine results in decreased activity of CDK2 protein Deferoxamine results in decreased expression of CDK2 protein |
CTD |
PMID:11468187 PMID:17631934 |
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NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403
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G |
Cdkn1a |
cyclin-dependent kinase inhibitor 1A |
increases expression multiple interactions decreases expression |
ISO EXP |
Deferoxamine results in increased expression of CDKN1A mRNA; Deferoxamine results in increased expression of CDKN1A protein [Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of CDKN1A mRNA; [Glucose co-treated with Deferoxamine] results in increased expression of CDKN1A mRNA; Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of CDKN1A mRNA]; MIR184 mRNA inhibits the reaction [[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of CDKN1A mRNA] Deferoxamine results in decreased expression of CDKN1A protein |
CTD |
PMID:10397746 PMID:10559391 PMID:11468187 PMID:12807743 PMID:16227210 PMID:23483119 PMID:33962019 PMID:35690295 More...
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NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
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G |
Cdkn1b |
cyclin-dependent kinase inhibitor 1B |
multiple interactions |
ISO |
[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of CDKN1B mRNA; [Glucose co-treated with Deferoxamine] results in increased expression of CDKN1B mRNA; Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of CDKN1B mRNA] |
CTD |
PMID:33962019 PMID:35690295 |
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NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982
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G |
Ckb |
creatine kinase B |
multiple interactions |
EXP |
[Deferoxamine co-treated with Acetylcysteine] inhibits the reaction [Acetaminophen results in decreased activity of CKB protein]; [Deferoxamine co-treated with Acetylcysteine] inhibits the reaction [Carbon Tetrachloride results in decreased activity of CKB protein] |
CTD |
PMID:19688255 |
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NCBI chr 6:130,729,420...130,732,301
Ensembl chr 6:130,729,423...130,732,315
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G |
Col1a1 |
collagen type I alpha 1 chain |
multiple interactions |
EXP |
Deferoxamine inhibits the reaction [Asbestos, Amosite results in increased expression of COL1A1 mRNA] |
CTD |
PMID:11306436 |
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NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
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G |
Cox4i1 |
cytochrome c oxidase subunit 4i1 |
multiple interactions |
ISO |
Deferoxamine inhibits the reaction [EPAS1 protein results in increased degradation of COX4I1 protein] |
CTD |
PMID:18515279 |
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NCBI chr19:48,721,680...48,727,920
Ensembl chr19:48,721,199...48,727,921
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G |
Cp |
ceruloplasmin |
multiple interactions |
ISO |
Deferoxamine inhibits the reaction [CP protein results in increased oxidation of 3-carboxy-2,2,5,5-tetramethylpyrrolidin-1-yloxyl] |
CTD |
PMID:22824865 |
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NCBI chr 2:102,439,433...102,498,075
Ensembl chr 2:102,439,624...102,498,075
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G |
Creb1 |
cAMP responsive element binding protein 1 |
increases activity |
EXP |
Deferoxamine results in increased activity of CREB1 protein |
CTD |
PMID:10559391 |
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NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
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G |
Crp |
C-reactive protein |
multiple interactions |
EXP |
Deferoxamine inhibits the reaction [Copper Sulfate results in increased secretion of CRP protein] |
CTD |
PMID:30431687 |
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NCBI chr13:85,131,635...85,175,179
Ensembl chr13:85,124,977...85,175,178
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G |
Csf2 |
colony stimulating factor 2 |
multiple interactions |
ISO |
Deferoxamine inhibits the reaction [Particulate Matter results in increased expression of CSF2 mRNA] |
CTD |
PMID:20801209 PMID:21703343 |
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NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199
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G |
Ctnnb1 |
catenin beta 1 |
multiple interactions |
ISO |
[Oxygen deficiency co-treated with Paclitaxel co-treated with FV-429 compound co-treated with Deferoxamine] affects the localization of CTNNB1 protein; Deferoxamine inhibits the reaction [ferumoxides results in increased activity of CTNNB1 protein] |
CTD |
PMID:20338187 PMID:34648812 |
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NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
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G |
Ctsk |
cathepsin K |
multiple interactions decreases expression |
ISO |
Deferoxamine inhibits the reaction [TF protein results in increased expression of CTSK mRNA]; TF protein affects the reaction [Deferoxamine results in decreased expression of CTSK mRNA] |
CTD |
PMID:31238089 |
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NCBI chr 2:183,058,586...183,069,551
Ensembl chr 2:183,058,569...183,069,550
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G |
Cxcl2 |
C-X-C motif chemokine ligand 2 |
multiple interactions |
EXP |
Deferoxamine promotes the reaction [Asbestos, Amphibole results in increased expression of CXCL2] |
CTD |
PMID:21605006 |
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NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075
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G |
Cybb |
cytochrome b-245 beta chain |
multiple interactions |
ISO |
[Deferoxamine co-treated with Benzene] results in increased expression of CYBB protein; Deferoxamine inhibits the reaction [Benzene results in increased expression of CYBB mRNA] |
CTD |
PMID:35661779 |
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NCBI chr X:13,360,583...13,392,517
Ensembl chr X:13,359,430...13,392,586
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G |
Cycs |
cytochrome c, somatic |
multiple interactions increases expression |
ISO |
[Glucose co-treated with Deferoxamine] results in increased expression of CYCS mRNA; Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of CYCS mRNA] Deferoxamine results in increased expression of CYCS mRNA |
CTD |
PMID:33962019 |
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NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054
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G |
Cyp1a1 |
cytochrome P450, family 1, subfamily a, polypeptide 1 |
multiple interactions |
ISO |
Deferoxamine inhibits the reaction [Particulate Matter results in increased expression of CYP1A1 mRNA] Deferoxamine inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]; ferrous sulfate inhibits the reaction [Deferoxamine inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]] |
CTD |
PMID:10799651 PMID:10823667 PMID:20801209 PMID:21703343 |
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NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
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G |
Cyp2e1 |
cytochrome P450, family 2, subfamily e, polypeptide 1 |
multiple interactions |
EXP |
Deferoxamine inhibits the reaction [CYP2E1 protein results in increased reduction of tirapazamine] |
CTD |
PMID:7710944 |
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NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
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G |
Cyp3a2 |
cytochrome P450, family 3, subfamily a, polypeptide 2 |
decreases expression |
ISO |
Deferoxamine results in decreased expression of CYP3A4 mRNA; Deferoxamine results in decreased expression of CYP3A4 protein |
CTD |
PMID:19695866 |
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NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008
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G |
Ddit3 |
DNA-damage inducible transcript 3 |
multiple interactions |
ISO |
Deferoxamine promotes the reaction [manganese chloride results in increased expression of DDIT3 protein] |
CTD |
PMID:23764342 |
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NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
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G |
Des |
desmin |
multiple interactions increases expression |
ISO |
Deferoxamine inhibits the reaction [Artesunate results in decreased expression of DES mRNA] Deferoxamine results in increased expression of DES mRNA |
CTD |
PMID:30551460 |
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NCBI chr 9:76,850,979...76,858,695
Ensembl chr 9:76,850,982...76,858,699
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G |
Diablo |
diablo, IAP-binding mitochondrial protein |
increases expression multiple interactions |
ISO |
Deferoxamine results in increased expression of DIABLO mRNA [Glucose co-treated with Deferoxamine] results in increased expression of DIABLO mRNA; Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of DIABLO mRNA] |
CTD |
PMID:33962019 |
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NCBI chr12:33,055,784...33,070,400
Ensembl chr12:33,055,263...33,070,387
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G |
Dicer1 |
dicer 1 ribonuclease III |
decreases expression |
ISO |
Deferoxamine results in decreased expression of DICER1 mRNA; Deferoxamine results in decreased expression of DICER1 protein |
CTD |
PMID:25351418 |
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NCBI chr 6:123,627,529...123,692,278
Ensembl chr 6:123,631,250...123,693,965
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G |
Dio2 |
iodothyronine deiodinase 2 |
increases activity |
EXP |
Deferoxamine results in increased activity of DIO2 protein |
CTD |
PMID:17615150 |
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NCBI chr 6:109,665,523...109,679,809
Ensembl chr 6:109,665,523...109,679,809
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G |
Dnm1l |
dynamin 1-like |
multiple interactions |
ISO |
Deferoxamine inhibits the reaction [ferric ammonium citrate results in decreased phosphorylation of DNM1L protein] [Glucose co-treated with Deferoxamine] results in increased expression of DNM1L mRNA; Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of DNM1L mRNA] |
CTD |
PMID:26318285 PMID:33962019 |
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NCBI chr11:84,581,216...84,632,382
Ensembl chr11:84,581,216...84,631,482
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G |
Dnmt1 |
DNA methyltransferase 1 |
increases expression decreases expression |
ISO |
Deferoxamine results in increased expression of DNMT1 mRNA Deferoxamine results in decreased expression of DNMT1 mRNA |
CTD |
PMID:23483119 |
|
NCBI chr 8:19,440,611...19,486,659
Ensembl chr 8:19,440,611...19,486,659
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G |
Dnmt3a |
DNA methyltransferase 3 alpha |
decreases expression increases expression |
ISO |
Deferoxamine results in decreased expression of DNMT3A mRNA Deferoxamine results in increased expression of DNMT3A mRNA |
CTD |
PMID:23483119 |
|
NCBI chr 6:26,791,517...26,902,161
Ensembl chr 6:26,822,609...26,896,687
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G |
Dnmt3b |
DNA methyltransferase 3 beta |
decreases expression increases expression |
ISO |
Deferoxamine results in decreased expression of DNMT3B mRNA Deferoxamine results in increased expression of DNMT3B mRNA |
CTD |
PMID:23483119 |
|
NCBI chr 3:142,130,592...142,169,124
Ensembl chr 3:142,130,592...142,169,124
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G |
Duox1 |
dual oxidase 1 |
multiple interactions |
ISO |
Deferoxamine inhibits the reaction [Particulate Matter results in increased expression of DUOX1 mRNA] |
CTD |
PMID:21703343 |
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NCBI chr 3:109,260,526...109,295,588
Ensembl chr 3:109,262,397...109,295,563
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G |
Duox2 |
dual oxidase 2 |
multiple interactions |
ISO |
Deferoxamine inhibits the reaction [Particulate Matter results in increased expression of DUOX2 mRNA] |
CTD |
PMID:21703343 |
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NCBI chr 3:109,223,809...109,247,023
Ensembl chr 3:109,226,924...109,245,902
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G |
Dusp1 |
dual specificity phosphatase 1 |
increases expression |
EXP |
Deferoxamine results in increased expression of DUSP1 mRNA |
CTD |
PMID:11577072 |
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NCBI chr10:16,680,489...16,683,276
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G |
Edn1 |
endothelin 1 |
increases expression |
EXP |
Deferoxamine results in increased expression of EDN1 protein |
CTD |
PMID:9357851 |
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NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885
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G |
Egfr |
epidermal growth factor receptor |
multiple interactions |
ISO |
[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of EGFR mRNA; Deferoxamine inhibits the reaction [Asbestos, Crocidolite results in decreased activity of and results in decreased phosphorylation of EGFR protein]; MIR184 mRNA inhibits the reaction [[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of EGFR mRNA] |
CTD |
PMID:15626777 PMID:35690295 |
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NCBI chr14:91,176,931...91,349,722
Ensembl chr14:91,177,067...91,344,382
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G |
Egln1 |
egl-9 family hypoxia-inducible factor 1 |
decreases expression |
ISO |
Deferoxamine results in decreased expression of EGLN1 protein |
CTD |
PMID:22245592 |
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NCBI chr19:52,867,914...52,907,169
Ensembl chr19:52,869,486...52,907,777
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G |
Ehmt2 |
euchromatic histone lysine methyltransferase 2 |
decreases expression |
ISO |
Deferoxamine results in decreased expression of EHMT2 mRNA |
CTD |
PMID:23483119 |
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NCBI chr20:3,919,623...3,936,751
Ensembl chr20:3,919,624...3,941,547
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G |
Elane |
elastase, neutrophil expressed |
multiple interactions |
ISO |
Deferoxamine inhibits the reaction [ELANE protein results in increased expression of MUC5AC mRNA] |
CTD |
PMID:11919081 |
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NCBI chr 7:9,817,251...9,819,174
Ensembl chr 7:9,817,252...9,819,100
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G |
Eno1 |
enolase 1 |
increases expression |
ISO |
Deferoxamine results in increased expression of ENO1 mRNA |
CTD |
PMID:16227210 |
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NCBI chr 5:160,719,951...160,731,337
Ensembl chr 5:160,719,951...160,731,336
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G |
Epas1 |
endothelial PAS domain protein 1 |
multiple interactions increases expression increases stability |
ISO EXP |
Deferoxamine inhibits the reaction [EPAS1 protein results in increased degradation of COX4I1 protein] Deferoxamine results in increased expression of EPAS1 protein Deferoxamine results in increased stability of EPAS1 protein |
CTD |
PMID:18353899 PMID:18515279 PMID:21558026 PMID:26735578 PMID:27287256 |
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NCBI chr 6:7,790,236...7,871,246
Ensembl chr 6:7,790,647...7,871,228
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G |
Epo |
erythropoietin |
increases expression increases stability multiple interactions |
ISO EXP |
Deferoxamine results in increased expression of EPO mRNA Deferoxamine deficiency results in increased expression of EPO mRNA; Deferoxamine results in increased expression of EPO mRNA Deferoxamine deficiency results in increased stability of EPO mRNA Deferoxamine results in increased expression of EPO mRNA; Deferoxamine results in increased expression of EPO protein Deferoxamine inhibits the reaction [Reactive Oxygen Species results in decreased expression of EPO protein] |
CTD |
PMID:9927288 PMID:10559391 PMID:10699462 PMID:10756076 PMID:21558026 |
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NCBI chr12:19,204,258...19,207,948
Ensembl chr12:19,204,508...19,207,946
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G |
Ern1 |
endoplasmic reticulum to nucleus signaling 1 |
multiple interactions |
ISO |
Deferoxamine promotes the reaction [Palmitic Acid results in increased phosphorylation of ERN1 protein] |
CTD |
PMID:32283200 |
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NCBI chr10:91,326,889...91,421,201
Ensembl chr10:91,330,654...91,421,029
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G |
Ero1a |
endoplasmic reticulum oxidoreductase 1 alpha |
increases expression |
ISO EXP |
Deferoxamine results in increased expression of ERO1A mRNA |
CTD |
PMID:12752442 |
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NCBI chr15:18,495,037...18,530,440
Ensembl chr15:18,492,945...18,530,478
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G |
Erp29 |
endoplasmic reticulum protein 29 |
decreases expression multiple interactions |
ISO |
Deferoxamine results in decreased expression of ERP29 protein ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of ERP29 protein] |
CTD |
PMID:19515424 |
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NCBI chr12:35,089,698...35,095,952
Ensembl chr12:35,089,707...35,096,376
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G |
Exo1 |
exonuclease 1 |
multiple interactions |
ISO |
[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of EXO1 mRNA; Antineoplastic Agents, Immunological inhibits the reaction [[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of EXO1 mRNA]; MIR184 mRNA inhibits the reaction [[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of EXO1 mRNA] |
CTD |
PMID:35690295 |
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NCBI chr13:87,809,725...87,834,654
Ensembl chr13:87,809,810...87,834,654
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G |
F3 |
coagulation factor III, tissue factor |
multiple interactions |
ISO |
Deferoxamine inhibits the reaction [ferric ammonium citrate results in increased expression of F3 mRNA] |
CTD |
PMID:25858758 |
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NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668
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G |
Fabp4 |
fatty acid binding protein 4 |
decreases expression |
ISO |
Deferoxamine results in decreased expression of FABP4 mRNA |
CTD |
PMID:12032628 |
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NCBI chr 2:91,580,858...91,585,578
Ensembl chr 2:91,580,885...91,585,578
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G |
Fasn |
fatty acid synthase |
multiple interactions |
ISO |
[Paclitaxel co-treated with FV-429 compound co-treated with Deferoxamine] promotes the reaction [Oxygen deficiency results in increased expression of FASN protein]; Deferoxamine promotes the reaction [Oxygen deficiency results in increased expression of FASN protein] |
CTD |
PMID:34648812 |
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NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
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G |
Fech |
ferrochelatase |
decreases expression multiple interactions |
ISO |
Deferoxamine results in decreased expression of FECH protein ferric chloride inhibits the reaction [Deferoxamine results in decreased expression of FECH protein] |
CTD |
PMID:30517741 |
|
NCBI chr18:57,945,123...57,978,327
Ensembl chr18:57,945,122...57,979,348
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G |
Fis1 |
fission, mitochondrial 1 |
multiple interactions |
ISO |
[Glucose co-treated with Deferoxamine] results in increased expression of FIS1 mRNA; Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of FIS1 mRNA] |
CTD |
PMID:33962019 |
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NCBI chr12:19,708,558...19,723,392
Ensembl chr12:19,708,558...19,723,377
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G |
Fn1 |
fibronectin 1 |
multiple interactions |
ISO |
Deferoxamine inhibits the reaction [Artesunate results in decreased expression of FN1 mRNA] |
CTD |
PMID:30551460 |
|
NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678
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G |
Fth1 |
ferritin heavy chain 1 |
decreases expression multiple interactions |
ISO EXP |
Deferoxamine results in decreased expression of FTH1 protein Deferoxamine inhibits the reaction [Benzene results in increased expression of FTH1 mRNA]; Deferoxamine inhibits the reaction [Iron-Dextran Complex results in increased expression of FTH1 protein] Deferoxamine inhibits the reaction [di-n-propyldithiocarbamate results in decreased expression of FTH1 protein] [Deferoxamine results in decreased abundance of Iron] which results in decreased expression of FTH1 mRNA |
CTD |
PMID:15893546 PMID:16568477 PMID:16777245 PMID:17469137 PMID:32687844 PMID:34044072 PMID:35661779 More...
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NCBI chr 1:206,627,142...206,629,430
Ensembl chr 1:206,627,103...206,725,424
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G |
Ftl1 |
ferritin light chain 1 |
multiple interactions decreases expression |
ISO EXP |
[Deferoxamine results in decreased abundance of Iron] which results in decreased expression of FTL mRNA; Deferoxamine inhibits the reaction [Doxorubicin promotes the reaction [Iron binds to [FTL protein binds to FTMT protein]]]; Deferoxamine inhibits the reaction [Iron binds to [FTL protein binds to FTMT protein]] Deferoxamine inhibits the reaction [Benzene results in increased expression of FTL1 protein] Deferoxamine results in decreased expression of FTL1 protein |
CTD |
PMID:12393473 PMID:12644586 PMID:15893546 PMID:16568477 PMID:35661779 |
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NCBI chr 1:95,936,390...95,938,234
Ensembl chr 1:95,936,387...95,939,725 Ensembl chr10:95,936,387...95,939,725
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G |
Ftmt |
ferritin mitochondrial |
multiple interactions |
ISO |
Deferoxamine inhibits the reaction [Doxorubicin promotes the reaction [Iron binds to [FTL protein binds to FTMT protein]]]; Deferoxamine inhibits the reaction [Iron binds to [FTL protein binds to FTMT protein]] |
CTD |
PMID:12644586 |
|
NCBI chr18:45,758,874...45,760,123
Ensembl chr18:45,758,874...45,760,123
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G |
Gadd45a |
growth arrest and DNA-damage-inducible, alpha |
increases expression |
ISO |
Deferoxamine results in increased expression of GADD45A mRNA |
CTD |
PMID:10397746 PMID:11468187 |
|
NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115
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G |
Gapdh |
glyceraldehyde-3-phosphate dehydrogenase |
decreases expression multiple interactions |
ISO |
Deferoxamine results in decreased expression of GAPDH protein ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of GAPDH protein] |
CTD |
PMID:19515424 |
|
NCBI chr 4:157,962,312...157,967,158
Ensembl chr 4:157,962,343...157,966,235
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G |
Gas1 |
growth arrest-specific 1 |
multiple interactions |
ISO |
[Deferoxamine results in decreased abundance of Iron] which results in decreased expression of GAS1 mRNA |
CTD |
PMID:12393473 |
|
NCBI chr17:4,482,014...4,485,155
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G |
Gbe1 |
1,4-alpha-glucan branching enzyme 1 |
increases expression |
ISO |
Deferoxamine results in increased expression of GBE1 mRNA |
CTD |
PMID:15094311 |
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NCBI chr11:8,734,806...9,000,226
Ensembl chr11:8,734,820...9,000,210
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G |
Gck |
glucokinase |
affects expression |
EXP |
Deferoxamine affects the expression of GCK mRNA |
CTD |
PMID:9761743 |
|
NCBI chr14:80,785,060...80,829,842
Ensembl chr14:80,785,060...80,826,995
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G |
Gclc |
glutamate-cysteine ligase, catalytic subunit |
multiple interactions |
ISO |
Deferoxamine inhibits the reaction [Benzene results in decreased expression of GCLC mRNA] |
CTD |
PMID:35661779 |
|
NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
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G |
Glo1 |
glyoxalase 1 |
increases expression multiple interactions |
ISO |
Deferoxamine results in increased expression of GLO1 protein ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of GLO1 protein] |
CTD |
PMID:19515424 |
|
NCBI chr20:8,663,617...8,681,661
Ensembl chr20:8,662,801...8,681,649
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G |
Gosr1 |
golgi SNAP receptor complex member 1 |
multiple interactions |
ISO |
GOSR1 protein affects the reaction [Deferoxamine inhibits the reaction [Nitroprusside results in decreased phosphorylation of MAPK1 protein]]; GOSR1 protein affects the reaction [Deferoxamine inhibits the reaction [Nitroprusside results in decreased phosphorylation of MAPK3 protein]] |
CTD |
PMID:31066958 |
|
NCBI chr10:61,570,499...61,607,287
Ensembl chr10:61,450,494...61,607,177 Ensembl chr10:61,450,494...61,607,177
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G |
Gpx4 |
glutathione peroxidase 4 |
multiple interactions |
ISO |
Deferoxamine inhibits the reaction [Benzene results in decreased expression of GPX4 mRNA]; Deferoxamine inhibits the reaction [Benzene results in decreased expression of GPX4 protein]; Deferoxamine inhibits the reaction [Busulfan results in decreased expression of GPX4 protein] |
CTD |
PMID:32416107 PMID:35661779 |
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NCBI chr 7:9,650,186...9,652,982
Ensembl chr 7:9,650,185...9,652,982
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G |
Gsk3b |
glycogen synthase kinase 3 beta |
multiple interactions decreases phosphorylation |
ISO |
Deferoxamine inhibits the reaction [Fenretinide results in increased phosphorylation of GSK3B protein] Deferoxamine results in decreased phosphorylation of GSK3B protein |
CTD |
PMID:25246272 |
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NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
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G |
Gsr |
glutathione-disulfide reductase |
multiple interactions |
EXP |
Deferoxamine inhibits the reaction [Potassium Dichromate results in decreased activity of GSR protein] |
CTD |
PMID:22115772 |
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NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
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G |
Hamp |
hepcidin antimicrobial peptide |
multiple interactions decreases expression affects expression |
ISO EXP |
Deferoxamine inhibits the reaction [BMP6 protein results in increased expression of HAMP mRNA]; Deferoxamine promotes the reaction [ferric ammonium citrate results in decreased expression of HAMP mRNA]; ferric ammonium citrate affects the reaction [Deferoxamine inhibits the reaction [BMP6 protein results in increased expression of HAMP mRNA]] Deferoxamine results in decreased expression of HAMP protein Deferoxamine affects the expression of HAMP mRNA |
CTD |
PMID:21558026 PMID:25633564 |
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NCBI chr 1:86,170,926...86,172,865
Ensembl chr 1:86,170,901...86,172,891
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G |
Havcr1 |
hepatitis A virus cellular receptor 1 |
multiple interactions |
EXP |
Deferoxamine inhibits the reaction [Copper Sulfate results in increased expression of HAVCR1 protein] |
CTD |
PMID:30431687 |
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NCBI chr10:31,118,667...31,151,730
Ensembl chr10:31,119,088...31,151,698
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G |
Hif1a |
hypoxia inducible factor 1 subunit alpha |
multiple interactions increases expression increases stability increases activity decreases degradation affects localization |
ISO EXP |
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Deferoxamine results in increased expression of HIF1A protein]; 3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole inhibits the reaction [Deferoxamine results in increased expression of HIF1A protein]; [Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of HIF1A mRNA; [Deferoxamine results in decreased abundance of Iron] which results in increased expression of HIF1A mRNA; [Doxorubicin co-treated with Deferoxamine] results in increased expression of HIF1A protein; [Glucose co-treated with Deferoxamine] results in increased expression of HIF1A mRNA; [Paclitaxel co-treated with FV-429 compound co-treated with Deferoxamine] promotes the reaction [Oxygen deficiency results in increased expression of HIF1A protein]; Arsenic Trioxide promotes the reaction [Deferoxamine results in increased expression of HIF1A protein]; Cadmium inhibits the reaction [Deferoxamine results in increased expression of HIF1A protein]; Deferoxamine inhibits the reaction [myricetin inhibits the reaction [Formaldehyde results in increased expression of HIF1A mRNA]]; Deferoxamine inhibits the reaction [myricetin inhibits the reaction [Formaldehyde results in increased expression of HIF1A protein]]; Deferoxamine promotes the reaction [[HIF1A protein binds to VEGFA promoter] which results in increased expression of VEGFA mRNA]; Deferoxamine promotes the reaction [Oxygen deficiency results in increased expression of HIF1A protein]; Deferoxamine results in increased expression of and results in increased stability of HIF1A protein; Deferoxamine results in increased stability of and results in increased expression of HIF1A protein; dihydrotanshinone I inhibits the reaction [Deferoxamine results in increased expression of HIF1A protein]; ferric citrate inhibits the reaction [Deferoxamine results in increased expression of HIF1A protein]; Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of HIF1A mRNA]; MIR184 mRNA inhibits the reaction [[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of HIF1A mRNA]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [Deferoxamine results in increased expression of HIF1A protein]; ST6GAL1 protein promotes the reaction [Deferoxamine results in increased expression of HIF1A protein]; TP53 gene mutant form promotes the reaction [Deferoxamine results in increased expression of HIF1A protein] Deferoxamine results in increased expression of HIF1A mRNA; Deferoxamine results in increased expression of HIF1A protein Deferoxamine results in increased stability of HIF1A protein 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Deferoxamine results in increased expression of HIF1A protein]; ferric citrate inhibits the reaction [Deferoxamine results in increased expression of HIF1A protein] Deferoxamine results in increased activity of HIF1A protein [Deferoxamine results in increased activity of HIF1A protein] which results in decreased susceptibility to Carmustine Deferoxamine results in decreased degradation of HIF1A protein Deferoxamine affects the localization of HIF1A protein |
CTD |
PMID:10559391 PMID:10866824 PMID:11286986 PMID:12393473 PMID:14604972 PMID:14980978 PMID:15840558 PMID:15902299 PMID:16227210 PMID:16330433 PMID:16374551 PMID:16527254 PMID:16772336 PMID:16775626 PMID:17015263 PMID:17364964 PMID:18655187 PMID:19695866 PMID:20546814 PMID:21558026 PMID:22245592 PMID:23483119 PMID:24403227 PMID:26282490 PMID:27287256 PMID:29475939 PMID:30382123 PMID:33962019 PMID:34126102 PMID:34648812 PMID:35690295 PMID:36116563 More...
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NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
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G |
Hif3a |
hypoxia inducible factor 3 subunit alpha |
increases expression |
ISO |
Deferoxamine results in increased expression of HIF3A protein |
CTD |
PMID:16775626 |
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NCBI chr 1:77,718,110...77,750,448
Ensembl chr 1:77,722,471...77,749,758
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G |
Hk2 |
hexokinase 2 |
increases expression multiple interactions |
ISO |
Deferoxamine results in increased expression of HK2 protein Deferoxamine inhibits the reaction [myricetin inhibits the reaction [Formaldehyde results in increased expression of HK2 mRNA]]; Deferoxamine inhibits the reaction [myricetin inhibits the reaction [Formaldehyde results in increased expression of HK2 protein]]; Doxorubicin inhibits the reaction [Deferoxamine results in increased expression of HK2 protein] |
CTD |
PMID:34126102 PMID:36116563 |
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NCBI chr 4:115,234,509...115,283,530
Ensembl chr 4:115,234,509...115,283,530
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G |
Hmox1 |
heme oxygenase 1 |
multiple interactions decreases degradation decreases expression |
ISO EXP |
Deferoxamine inhibits the reaction [HMOX1 protein results in increased abundance of Superoxides] Deferoxamine results in decreased degradation of HMOX1 protein Deferoxamine results in decreased expression of HMOX1 mRNA [Deferoxamine results in decreased abundance of Iron] which results in decreased expression of HMOX1 mRNA; Deferoxamine affects the reaction [7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide affects the expression of HMOX1 protein]; Deferoxamine inhibits the reaction [Cadmium Chloride results in increased activity of HMOX1 protein]; Deferoxamine inhibits the reaction [Cadmium Chloride results in increased expression of HMOX1 mRNA]; Deferoxamine inhibits the reaction [Cadmium Chloride results in increased expression of HMOX1 protein]; Deferoxamine inhibits the reaction [Ethacrynic Acid affects the localization of HMOX1 protein]; Deferoxamine inhibits the reaction [Ethacrynic Acid results in increased expression of HMOX1 mRNA]; Deferoxamine inhibits the reaction [Fenretinide results in increased expression of HMOX1 protein]; Deferoxamine inhibits the reaction [Oxygen results in increased expression of HMOX1 mRNA]; Deferoxamine inhibits the reaction [phenethyl isothiocyanate results in increased expression of HMOX1 mRNA]; Deferoxamine inhibits the reaction [phenethyl isothiocyanate results in increased expression of HMOX1 protein]; Deferoxamine inhibits the reaction [sulforaphane results in increased expression of HMOX1 mRNA]; Deferoxamine inhibits the reaction [Zinc results in increased expression of HMOX1 mRNA]; Deferoxamine inhibits the reaction [Zinc results in increased expression of HMOX1 protein]; ferrous sulfate inhibits the reaction [Deferoxamine inhibits the reaction [Cadmium Chloride results in increased activity of HMOX1 protein]]; ferrous sulfate inhibits the reaction [Deferoxamine inhibits the reaction [Cadmium Chloride results in increased expression of HMOX1 mRNA]]; ferrous sulfate inhibits the reaction [Deferoxamine inhibits the reaction [phenethyl isothiocyanate results in increased expression of HMOX1 mRNA]]; ferrous sulfate inhibits the reaction [Deferoxamine inhibits the reaction [phenethyl isothiocyanate results in increased expression of HMOX1 protein]]; ferrous sulfate inhibits the reaction [Deferoxamine inhibits the reaction [sulforaphane results in increased expression of HMOX1 mRNA]] Deferoxamine inhibits the reaction [HMOX1 protein results in increased abundance of Superoxides]; Deferoxamine inhibits the reaction [Nitroprusside results in increased expression of HMOX1 protein] |
CTD |
PMID:9747510 PMID:10814519 PMID:12393473 PMID:16439612 PMID:18073186 PMID:19384570 PMID:20934533 PMID:22564156 PMID:25246272 PMID:26945724 PMID:36450496 More...
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NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
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G |
Hspa1b |
heat shock protein family A (Hsp70) member 1B |
multiple interactions decreases expression |
ISO |
ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of HSPA1A protein] Deferoxamine results in decreased expression of HSPA1A protein |
CTD |
PMID:19515424 |
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NCBI chr20:3,870,765...3,873,221
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G |
Hspa1l |
heat shock protein family A (Hsp70) member 1 like |
multiple interactions |
ISO |
[Deferoxamine results in decreased abundance of Iron] which results in decreased expression of HSPA1L mRNA |
CTD |
PMID:12393473 |
|
NCBI chr20:3,848,843...3,855,571
Ensembl chr20:3,848,843...3,855,571
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G |
Hspa6l-ps1 |
heat shock protein family A (Hsp70) member 6 like, pseudogene 1 |
multiple interactions |
ISO |
[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of HSPA6 mRNA; Antineoplastic Agents, Immunological inhibits the reaction [[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of HSPA6 mRNA]; MIR184 mRNA inhibits the reaction [[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of HSPA6 mRNA] |
CTD |
PMID:35690295 |
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NCBI chr13:83,271,340...83,275,267
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G |
Hspa9 |
heat shock protein family A (Hsp70) member 9 |
multiple interactions |
ISO |
[Deferoxamine results in decreased abundance of Iron] which results in decreased expression of HSPA9 mRNA |
CTD |
PMID:12393473 |
|
NCBI chr18:26,536,131...26,554,294
Ensembl chr18:26,535,798...26,554,292
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G |
Hspd1 |
heat shock protein family D (Hsp60) member 1 |
multiple interactions decreases expression |
ISO |
[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of HSPD1 mRNA; ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of HSPD1 protein]; MIR184 mRNA inhibits the reaction [[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of HSPD1 mRNA] Deferoxamine results in decreased expression of HSPD1 protein |
CTD |
PMID:19515424 PMID:24170104 PMID:35690295 |
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NCBI chr 9:56,579,195...56,590,011
Ensembl chr 9:56,579,201...56,589,662
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G |
Hsph1 |
heat shock protein family H (Hsp110) member 1 |
multiple interactions |
ISO |
[Deferoxamine results in decreased abundance of Iron] which results in decreased expression of HSPH1 mRNA |
CTD |
PMID:12393473 |
|
NCBI chr12:5,390,916...5,410,224
Ensembl chr12:5,390,922...5,410,224
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G |
Icam1 |
intercellular adhesion molecule 1 |
multiple interactions |
ISO |
[Deferoxamine affects the abundance of Iron] inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]; [Deferoxamine affects the abundance of Iron] inhibits the reaction [TNF protein results in increased expression of ICAM1 protein] |
CTD |
PMID:12633744 |
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NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
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G |
Il10 |
interleukin 10 |
multiple interactions |
EXP |
Deferoxamine inhibits the reaction [Copper Sulfate results in decreased secretion of IL10 protein] |
CTD |
PMID:30431687 |
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NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
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G |
Il1a |
interleukin 1 alpha |
multiple interactions |
ISO |
Deferoxamine inhibits the reaction [Particulate Matter results in increased expression of IL1A mRNA] |
CTD |
PMID:21703343 |
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NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
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G |
Il1b |
interleukin 1 beta |
multiple interactions increases expression decreases expression |
ISO |
Deferoxamine inhibits the reaction [Particulate Matter results in increased expression of IL1B mRNA]; Deferoxamine promotes the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]; ferric chloride inhibits the reaction [Deferoxamine promotes the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]] Deferoxamine results in increased expression of IL1B mRNA Deferoxamine inhibits the reaction [Asbestos, Crocidolite results in increased secretion of IL1B protein] Deferoxamine results in decreased expression of IL1B mRNA |
CTD |
PMID:9851740 PMID:18403674 PMID:20801209 PMID:32816093 |
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NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
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G |
Il4 |
interleukin 4 |
multiple interactions |
EXP |
Deferoxamine inhibits the reaction [Mercuric Chloride results in increased expression of IL4 mRNA] |
CTD |
PMID:11222498 |
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NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
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G |
Il6 |
interleukin 6 |
multiple interactions |
ISO EXP |
Deferoxamine inhibits the reaction [2,2',4,4'-tetrabromodiphenyl ether results in increased expression of and results in increased secretion of IL6 protein]; Deferoxamine inhibits the reaction [Coal Ash results in increased expression of IL6 protein] Deferoxamine inhibits the reaction [Asbestos, Amphibole results in increased expression of IL6 mRNA] |
CTD |
PMID:9344885 PMID:22168577 PMID:24296301 |
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NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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G |
Ins1 |
insulin 1 |
increases secretion |
EXP |
Deferoxamine results in increased secretion of INS1 protein |
CTD |
PMID:30382123 |
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NCBI chr 1:251,244,973...251,245,540
Ensembl chr 1:251,244,973...251,245,536
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G |
Ireb2 |
iron responsive element binding protein 2 |
increases expression increases activity multiple interactions |
EXP ISO |
Deferoxamine results in increased expression of IREB2 protein Deferoxamine results in increased activity of IREB2 protein Deferoxamine inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased activity of IREB2 protein]; Deferoxamine results in increased expression of and results in increased activity of IREB2 protein |
CTD |
PMID:10397746 PMID:11054110 PMID:16135072 PMID:16568477 PMID:17469137 PMID:18073202 More...
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NCBI chr 8:55,228,080...55,311,613
Ensembl chr 8:55,228,085...55,311,611
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G |
Itgb3 |
integrin subunit beta 3 |
decreases expression multiple interactions |
ISO |
Deferoxamine results in decreased expression of ITGB3 mRNA Deferoxamine inhibits the reaction [TF protein results in increased expression of ITGB3 mRNA] |
CTD |
PMID:31238089 |
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NCBI chr10:89,509,917...89,564,679
Ensembl chr10:89,509,989...89,564,679
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G |
Jun |
Jun proto-oncogene, AP-1 transcription factor subunit |
multiple interactions |
ISO |
[Deferoxamine results in decreased abundance of Iron] which results in increased expression of JUN mRNA |
CTD |
PMID:12393473 |
|
NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
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G |
Kdm1a |
lysine demethylase 1A |
multiple interactions |
ISO |
Deferoxamine results in decreased expression of and results in decreased activity of KDM1A protein |
CTD |
PMID:23483119 |
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NCBI chr 5:148,782,976...148,838,319
Ensembl chr 5:148,782,976...148,838,319
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G |
Kdm3a |
lysine demethylase 3A |
increases expression |
ISO |
Deferoxamine results in increased expression of KDM3A protein |
CTD |
PMID:23546878 |
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NCBI chr 4:103,630,907...103,675,073
Ensembl chr 4:103,630,908...103,675,073
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G |
Kdm4a |
lysine demethylase 4A |
multiple interactions |
ISO |
Deferoxamine results in decreased expression of and results in decreased activity of KDM4A protein |
CTD |
PMID:23483119 |
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NCBI chr 5:131,672,754...131,719,534
Ensembl chr 5:131,672,754...131,719,501
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G |
Kdr |
kinase insert domain receptor |
multiple interactions |
ISO |
[Glucose co-treated with Deferoxamine] results in increased expression of KDR mRNA; Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of KDR mRNA] |
CTD |
PMID:33962019 |
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NCBI chr14:32,217,871...32,261,018
Ensembl chr14:32,217,871...32,261,018
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G |
Lcn2 |
lipocalin 2 |
multiple interactions increases expression |
ISO |
Deferoxamine affects the reaction [Magnetite Nanoparticles results in increased expression of LCN2 mRNA]; Deferoxamine inhibits the reaction [LCN2 protein results in decreased secretion of VEGFA protein] Deferoxamine results in increased expression of LCN2 mRNA |
CTD |
PMID:17114340 PMID:23086747 |
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NCBI chr 3:15,680,688...15,684,033
Ensembl chr 3:15,680,687...15,684,095
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G |
Ldha |
lactate dehydrogenase A |
increases expression multiple interactions |
ISO |
Deferoxamine results in increased expression of LDHA mRNA Deferoxamine inhibits the reaction [myricetin inhibits the reaction [Formaldehyde results in increased expression of LDHA mRNA]]; Deferoxamine inhibits the reaction [myricetin inhibits the reaction [Formaldehyde results in increased expression of LDHA protein]] |
CTD |
PMID:34998824 PMID:36116563 |
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NCBI chr 1:97,371,823...97,381,247
Ensembl chr 1:97,366,021...97,433,472
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G |
Lep |
leptin |
increases expression increases secretion |
ISO EXP |
Deferoxamine results in increased expression of LEP mRNA Deferoxamine results in increased secretion of LEP protein |
CTD |
PMID:12032628 |
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NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
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G |
Lipe |
lipase E, hormone sensitive type |
decreases expression |
ISO |
Deferoxamine results in decreased expression of LIPE mRNA |
CTD |
PMID:12032628 |
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NCBI chr 1:80,965,612...80,984,313
Ensembl chr 1:80,965,627...80,984,310
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G |
Lox |
lysyl oxidase |
multiple interactions |
ISO |
[Deferoxamine results in decreased abundance of Iron] which results in increased expression of LOX mRNA |
CTD |
PMID:12393473 |
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NCBI chr18:45,964,311...46,041,477
Ensembl chr18:45,967,343...46,041,477
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G |
Map1lc3a |
microtubule-associated protein 1 light chain 3 alpha |
multiple interactions |
ISO |
Deferoxamine inhibits the reaction [Hydrogen Peroxide affects the localization of MAP1LC3A protein] |
CTD |
PMID:21742779 |
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NCBI chr 3:143,783,024...143,784,670
Ensembl chr 3:143,783,024...143,784,670
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G |
Map1lc3b |
microtubule-associated protein 1 light chain 3 beta |
increases expression multiple interactions |
ISO |
Deferoxamine results in increased expression of MAP1LC3B protein Deferoxamine inhibits the reaction [di-n-propyldithiocarbamate results in increased expression of and results in increased lipidation of MAP1LC3B protein]; Iron affects the reaction [Deferoxamine results in increased expression of MAP1LC3B protein] |
CTD |
PMID:25301941 PMID:32687844 |
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NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690
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G |
Map3k5 |
mitogen-activated protein kinase kinase kinase 5 |
multiple interactions |
ISO |
Deferoxamine inhibits the reaction [Plant Extracts results in increased phosphorylation of MAP3K5 protein] |
CTD |
PMID:20206247 |
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NCBI chr 1:14,685,776...14,904,935
Ensembl chr 1:14,685,492...14,904,800
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G |
Mapk1 |
mitogen activated protein kinase 1 |
multiple interactions increases phosphorylation |
EXP ISO |
Deferoxamine inhibits the reaction [PDGFB protein results in increased phosphorylation of MAPK1 protein]; Deferoxamine promotes the reaction [Manganese results in increased phosphorylation of MAPK1 protein] Deferoxamine inhibits the reaction [Nitroprusside results in decreased phosphorylation of MAPK1 protein]; GOSR1 protein affects the reaction [Deferoxamine inhibits the reaction [Nitroprusside results in decreased phosphorylation of MAPK1 protein]] [Deferoxamine co-treated with TNFSF11 protein] results in decreased phosphorylation of MAPK1 protein; Deferoxamine inhibits the reaction [[Hydrogen Peroxide co-treated with TNFSF11 protein] results in increased phosphorylation of MAPK1 protein] Deferoxamine results in increased phosphorylation of MAPK1 protein |
CTD |
PMID:11933051 PMID:16527254 PMID:18032466 PMID:20368581 PMID:31066958 PMID:31238089 More...
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NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
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G |
Mapk3 |
mitogen activated protein kinase 3 |
multiple interactions increases phosphorylation |
EXP ISO |
Deferoxamine inhibits the reaction [PDGFB protein results in increased phosphorylation of MAPK3 protein]; Deferoxamine promotes the reaction [Manganese results in increased phosphorylation of MAPK3 protein] Deferoxamine inhibits the reaction [Nitroprusside results in decreased phosphorylation of MAPK3 protein]; GOSR1 protein affects the reaction [Deferoxamine inhibits the reaction [Nitroprusside results in decreased phosphorylation of MAPK3 protein]] [Deferoxamine co-treated with TNFSF11 protein] results in decreased phosphorylation of MAPK3 protein; Deferoxamine inhibits the reaction [[Hydrogen Peroxide co-treated with TNFSF11 protein] results in increased phosphorylation of MAPK3 protein] Deferoxamine results in increased phosphorylation of MAPK3 protein |
CTD |
PMID:11933051 PMID:16527254 PMID:18032466 PMID:20368581 PMID:31066958 PMID:31238089 More...
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NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
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G |
Mapk8 |
mitogen-activated protein kinase 8 |
increases phosphorylation multiple interactions |
ISO |
Deferoxamine results in increased phosphorylation of MAPK8 protein Deferoxamine inhibits the reaction [Plant Extracts results in increased phosphorylation of MAPK8 protein] |
CTD |
PMID:20206247 PMID:20368581 |
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NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
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G |
Mapk9 |
mitogen-activated protein kinase 9 |
increases phosphorylation multiple interactions |
ISO |
Deferoxamine results in increased phosphorylation of MAPK9 protein Deferoxamine inhibits the reaction [Plant Extracts results in increased phosphorylation of MAPK9 protein] |
CTD |
PMID:20206247 PMID:20368581 |
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NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178
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G |
Mcl1 |
MCL1 apoptosis regulator, BCL2 family member |
multiple interactions increases cleavage |
ISO |
Nitroprusside inhibits the reaction [Deferoxamine results in increased cleavage of MCL1 protein]; Vanadates inhibits the reaction [Deferoxamine results in increased cleavage of MCL1 protein] |
CTD |
PMID:16374551 |
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NCBI chr 2:183,219,137...183,235,676
Ensembl chr 2:183,219,220...183,222,303
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G |
Mff |
mitochondrial fission factor |
increases expression multiple interactions |
ISO |
Deferoxamine results in increased expression of MFF mRNA [Glucose co-treated with Deferoxamine] results in increased expression of MFF mRNA; Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of MFF mRNA] |
CTD |
PMID:33962019 |
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NCBI chr 9:84,007,798...84,036,039
Ensembl chr 9:84,007,798...84,036,039
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G |
Mfn2 |
mitofusin 2 |
multiple interactions |
ISO |
[Glucose co-treated with Deferoxamine] results in decreased expression of MFN2 mRNA; Melatonin affects the reaction [[Glucose co-treated with Deferoxamine] results in decreased expression of MFN2 mRNA] |
CTD |
PMID:33962019 |
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NCBI chr 5:158,304,285...158,335,502
Ensembl chr 5:158,304,287...158,335,342
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G |
Mief2 |
mitochondrial elongation factor 2 |
multiple interactions increases expression |
ISO |
[Glucose co-treated with Deferoxamine] results in increased expression of MIEF2 mRNA; Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of MIEF2 mRNA] Deferoxamine results in increased expression of MIEF2 mRNA |
CTD |
PMID:33962019 |
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NCBI chr10:45,408,055...45,414,144
Ensembl chr10:45,408,082...45,414,144
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G |
Mir155 |
microRNA 155 |
multiple interactions |
ISO |
[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of MIR155 mRNA; MIR184 mRNA inhibits the reaction [[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of MIR155 mRNA] |
CTD |
PMID:35690295 |
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NCBI chr11:23,774,654...23,774,718
Ensembl chr11:23,774,654...23,774,718
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G |
Mir184 |
microRNA 184 |
multiple interactions |
ISO |
[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of MIR184 mRNA; MIR184 mRNA inhibits the reaction [[Deferoxamine co-treated with tert-Butylhydroperoxide] results in decreased expression of BCL2 mRNA]; MIR184 mRNA inhibits the reaction [[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of AKT1 mRNA]; MIR184 mRNA inhibits the reaction [[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of APAF1 mRNA]; MIR184 mRNA inhibits the reaction [[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of ARNT mRNA]; MIR184 mRNA inhibits the reaction [[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of BAX mRNA]; MIR184 mRNA inhibits the reaction [[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of CASP3 mRNA]; MIR184 mRNA inhibits the reaction [[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of CASP8 mRNA]; MIR184 mRNA inhibits the reaction [[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of CDKN1A mRNA]; MIR184 mRNA inhibits the reaction [[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of EGFR mRNA]; MIR184 mRNA inhibits the reaction [[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of EXO1 mRNA]; MIR184 mRNA inhibits the reaction [[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of HIF1A mRNA]; MIR184 mRNA inhibits the reaction [[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of HSPA6 mRNA]; MIR184 mRNA inhibits the reaction [[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of HSPD1 mRNA]; MIR184 mRNA inhibits the reaction [[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of MIR155 mRNA]; MIR184 mRNA inhibits the reaction [[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of MLH1 mRNA]; MIR184 mRNA inhibits the reaction [[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of MMP3 mRNA]; MIR184 mRNA inhibits the reaction [[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of MMP9 mRNA]; MIR184 mRNA inhibits the reaction [[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of MTOR mRNA]; MIR184 mRNA inhibits the reaction [[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of PIK3R1 mRNA]; MIR184 mRNA inhibits the reaction [[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of SOD1 mRNA]; MIR184 mRNA inhibits the reaction [[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of TNFSF10 mRNA]; MIR184 mRNA inhibits the reaction [[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of TP53 mRNA]; MIR184 mRNA inhibits the reaction [[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of VEGFA mRNA] |
CTD |
PMID:35690295 |
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NCBI chr 8:90,343,134...90,343,210
Ensembl chr 8:90,343,134...90,343,210
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G |
Mir210 |
microRNA 210 |
increases expression increases expression |
ISO |
Deferoxamine results in increased expression of MIR210 mRNA desferrioxamine B increases expression of MIR210 miRNA in trophoblast cells |
CTD RGD |
PMID:24577088 PMID:22840297 |
RGD:155631283 |
NCBI chr 1:196,326,343...196,326,452
Ensembl chr 1:196,326,337...196,326,454
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G |
Mlh1 |
mutL homolog 1 |
multiple interactions |
ISO |
[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of MLH1 mRNA; Antineoplastic Agents, Immunological inhibits the reaction [[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of MLH1 mRNA]; MIR184 mRNA inhibits the reaction [[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of MLH1 mRNA] |
CTD |
PMID:35690295 |
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NCBI chr 8:111,196,468...111,233,721
Ensembl chr 8:111,196,468...111,233,617
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G |
Mmp1 |
matrix metallopeptidase 1 |
multiple interactions |
ISO |
[Deferoxamine co-treated with SOD2 protein] results in increased expression of MMP1 mRNA; Deferoxamine inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of MMP1 mRNA]; Deferoxamine inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of MMP1 protein]; Deferoxamine inhibits the reaction [[Amitrole co-treated with SOD2 protein] results in increased expression of MMP1 mRNA]; Deferoxamine inhibits the reaction [[Buthionine Sulfoximine co-treated with SOD2 protein] results in increased expression of MMP1 mRNA] |
CTD |
PMID:10464329 PMID:19136476 |
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NCBI chr 8:4,658,588...4,679,099
Ensembl chr 8:4,658,588...4,679,097
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G |
Mmp2 |
matrix metallopeptidase 2 |
multiple interactions decreases activity |
ISO |
Calcium Chloride inhibits the reaction [Deferoxamine results in decreased activity of MMP2 protein]; Deferoxamine inhibits the reaction [ferumoxides results in increased activity of MMP2 protein]; ferric chloride inhibits the reaction [Deferoxamine results in decreased activity of MMP2 protein] |
CTD |
PMID:10086886 PMID:20338187 |
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NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
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G |
Mmp3 |
matrix metallopeptidase 3 |
multiple interactions |
ISO |
[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of MMP3 mRNA; MIR184 mRNA inhibits the reaction [[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of MMP3 mRNA] |
CTD |
PMID:35690295 |
|
NCBI chr 8:4,640,397...4,653,963
Ensembl chr 8:4,640,416...4,653,961
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G |
Mmp9 |
matrix metallopeptidase 9 |
multiple interactions decreases expression |
ISO |
Deferoxamine inhibits the reaction [TF protein results in increased expression of MMP9 mRNA]; TF protein affects the reaction [Deferoxamine results in increased expression of MMP9 mRNA] [Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of MMP9 mRNA; Antineoplastic Agents, Immunological inhibits the reaction [[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of MMP9 mRNA]; MIR184 mRNA inhibits the reaction [[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of MMP9 mRNA] Deferoxamine results in decreased expression of MMP9 mRNA |
CTD |
PMID:31238089 PMID:35690295 |
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NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
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G |
Mrps9 |
mitochondrial ribosomal protein S9 |
multiple interactions increases expression |
ISO |
ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of MRPS9 protein] |
CTD |
PMID:19515424 |
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NCBI chr 9:45,113,554...45,172,375
Ensembl chr 9:45,113,554...45,172,375
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G |
Msr1 |
macrophage scavenger receptor 1 |
multiple interactions |
ISO |
Deferoxamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MSR1 mRNA] |
CTD |
PMID:9614211 |
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NCBI chr16:52,717,775...52,802,890
Ensembl chr16:52,717,732...52,799,676
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G |
Mt-atp6 |
mitochondrially encoded ATP synthase membrane subunit 6 |
decreases expression |
ISO |
Deferoxamine results in decreased expression of ATP6 mRNA |
CTD |
PMID:31238089 |
|
NCBI chr MT:7,919...8,599
Ensembl chr MT:7,919...8,599
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G |
Mt-atp8 |
mitochondrially encoded ATP synthase membrane subunit 8 |
decreases expression |
ISO |
Deferoxamine results in decreased expression of ATP8 mRNA |
CTD |
PMID:31238089 |
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NCBI chr MT:7,758...7,961
Ensembl chr MT:7,758...7,961
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G |
Mt-co1 |
mitochondrially encoded cytochrome c oxidase I |
decreases expression |
ISO |
Deferoxamine results in decreased expression of COX1 mRNA |
CTD |
PMID:31238089 |
|
NCBI chr MT:5,323...6,867
Ensembl chr MT:5,323...6,867
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G |
Mt-co2 |
mitochondrially encoded cytochrome c oxidase II |
decreases expression |
ISO |
Deferoxamine results in decreased expression of COX2 mRNA |
CTD |
PMID:31238089 |
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NCBI chr MT:7,006...7,689
Ensembl chr MT:7,006...7,689
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G |
Mt-co3 |
mitochondrially encoded cytochrome c oxidase III |
decreases expression |
ISO |
Deferoxamine results in decreased expression of COX3 mRNA |
CTD |
PMID:31238089 |
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NCBI chr MT:8,599...9,382
Ensembl chr MT:8,599...9,382
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G |
Mt-cyb |
mitochondrially encoded cytochrome b |
decreases expression |
ISO |
Deferoxamine results in decreased expression of CYTB mRNA |
CTD |
PMID:31238089 |
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NCBI chr MT:14,136...15,278
Ensembl chr MT:14,136...15,278
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G |
Mt-nd1 |
mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 1 |
decreases expression |
ISO |
Deferoxamine results in decreased expression of ND1 mRNA |
CTD |
PMID:31238089 |
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NCBI chr MT:2,740...3,694
Ensembl chr MT:2,740...3,694
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G |
Mt-nd2 |
mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 2 |
decreases expression |
ISO |
Deferoxamine results in decreased expression of ND2 mRNA |
CTD |
PMID:31238089 |
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NCBI chr MT:3,904...4,942
Ensembl chr MT:3,904...4,942
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G |
Mt-nd3 |
mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 3 |
decreases expression |
ISO |
Deferoxamine results in decreased expression of ND3 mRNA |
CTD |
PMID:31238089 |
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NCBI chr MT:9,451...9,798
Ensembl chr MT:9,451...9,798
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G |
Mt-nd4 |
mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 4 |
decreases expression |
ISO |
Deferoxamine results in decreased expression of ND4 mRNA |
CTD |
PMID:31238089 |
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NCBI chr MT:10,160...11,537
Ensembl chr MT:10,160...11,537
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G |
Mt-nd4l |
mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 4L |
decreases expression |
ISO |
Deferoxamine results in decreased expression of ND4L mRNA |
CTD |
PMID:31238089 |
|
NCBI chr MT:9,870...10,166
Ensembl chr MT:9,870...10,166
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G |
Mt-nd5 |
mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 5 |
decreases expression |
ISO |
Deferoxamine results in decreased expression of ND5 mRNA |
CTD |
PMID:31238089 |
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NCBI chr MT:11,736...13,565
Ensembl chr MT:11,736...13,565
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G |
Mt-nd6 |
mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 6 |
decreases expression |
ISO |
Deferoxamine results in decreased expression of ND6 mRNA |
CTD |
PMID:31238089 |
|
NCBI chr MT:13,543...14,061
Ensembl chr MT:13,543...14,061
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G |
Mt2A |
metallothionein 2A |
multiple interactions |
ISO |
[Deferoxamine results in decreased abundance of Iron] which results in increased expression of MT2A mRNA |
CTD |
PMID:12393473 |
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NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784
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G |
Mtor |
mechanistic target of rapamycin kinase |
multiple interactions |
ISO |
[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of MTOR mRNA; MIR184 mRNA inhibits the reaction [[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of MTOR mRNA] |
CTD |
PMID:35690295 |
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NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
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G |
Muc5ac |
mucin 5AC, oligomeric mucus/gel-forming |
multiple interactions |
ISO |
Deferoxamine inhibits the reaction [ELANE protein results in increased expression of MUC5AC mRNA] |
CTD |
PMID:11919081 |
|
NCBI chr 1:196,864,375...196,896,475
Ensembl chr 1:196,864,336...196,896,475
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G |
Myc |
MYC proto-oncogene, bHLH transcription factor |
increases degradation decreases expression multiple interactions |
ISO |
Deferoxamine results in increased degradation of MYC protein Deferoxamine results in decreased expression of MYC protein [Deferoxamine results in decreased abundance of Iron] which results in decreased expression of MYC mRNA |
CTD |
PMID:12393473 PMID:20046830 PMID:22245592 |
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NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
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G |
Ncoa4 |
nuclear receptor coactivator 4 |
multiple interactions |
ISO |
Deferoxamine inhibits the reaction [di-n-propyldithiocarbamate results in increased expression of NCOA4 protein]; Deferoxamine promotes the reaction [Palmitic Acid results in increased expression of NCOA4 protein] |
CTD |
PMID:32283200 PMID:32687844 |
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NCBI chr16:7,389,222...7,409,564
Ensembl chr16:7,366,542...7,409,641 Ensembl chr16:7,366,542...7,409,641
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G |
Ndrg1 |
N-myc downstream regulated 1 |
increases expression decreases response to substance |
ISO |
Deferoxamine results in increased expression of NDRG1 mRNA; Deferoxamine results in increased expression of NDRG1 protein NDRG1 protein results in decreased susceptibility to Deferoxamine |
CTD |
PMID:11006124 PMID:24532803 |
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NCBI chr 7:98,684,487...98,725,869
Ensembl chr 7:98,684,487...98,725,880
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G |
Ndufb8 |
NADH:ubiquinone oxidoreductase subunit B8 |
decreases expression |
ISO |
Deferoxamine results in decreased expression of NDUFB8 protein |
CTD |
PMID:31238089 |
|
NCBI chr 1:243,408,659...243,413,701
Ensembl chr 1:243,408,619...243,413,817
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G |
Nes |
nestin |
decreases expression |
ISO |
Deferoxamine results in decreased expression of NES mRNA |
CTD |
PMID:16772336 |
|
NCBI chr 2:173,437,867...173,447,777
Ensembl chr 2:173,438,734...173,447,777
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G |
Nfe2l2 |
NFE2 like bZIP transcription factor 2 |
multiple interactions |
ISO |
Deferoxamine inhibits the reaction [7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of NFE2L2 protein]; Deferoxamine inhibits the reaction [Nitroprusside results in decreased expression of NFE2L2 protein]; Deferoxamine inhibits the reaction [phenethyl isothiocyanate results in increased expression of and affects the localization of NFE2L2 protein]; ferrous sulfate inhibits the reaction [Deferoxamine inhibits the reaction [Ethacrynic Acid affects the localization of NFE2L2 protein]]; ferrous sulfate inhibits the reaction [Deferoxamine inhibits the reaction [phenethyl isothiocyanate results in increased expression of and affects the localization of NFE2L2 protein]] Deferoxamine inhibits the reaction [Busulfan results in decreased expression of NFE2L2 protein] |
CTD |
PMID:26945724 PMID:31066958 PMID:32416107 PMID:36450496 |
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NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737
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G |
Nfkbia |
NFKB inhibitor alpha |
multiple interactions |
EXP |
Deferoxamine inhibits the reaction [Copper Sulfate results in increased expression of NFKBIA mRNA] |
CTD |
PMID:30431687 |
|
NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
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G |
Nos2 |
nitric oxide synthase 2 |
multiple interactions increases expression |
EXP ISO |
Nitrites inhibits the reaction [[TNF protein results in increased activity of NOS2 protein] which results in increased chemical synthesis of Deferoxamine] [Deferoxamine results in increased expression of NOS2 mRNA] which results in increased abundance of Nitric Oxide |
CTD |
PMID:7532384 PMID:18073202 |
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NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
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G |
Nqo1 |
NAD(P)H quinone dehydrogenase 1 |
decreases expression multiple interactions |
ISO |
Deferoxamine results in decreased expression of NQO1 mRNA Deferoxamine inhibits the reaction [Benzo(a)pyrene results in increased expression of NQO1 mRNA] |
CTD |
PMID:14645679 |
|
NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
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G |
Olr1 |
oxidized low density lipoprotein receptor 1 |
decreases expression |
ISO |
Deferoxamine results in decreased expression of OLR1 protein |
CTD |
PMID:24170104 |
|
NCBI chr 4:162,926,436...162,949,057
Ensembl chr 4:162,926,439...162,948,523
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G |
Opa1 |
OPA1, mitochondrial dynamin like GTPase |
multiple interactions increases expression |
ISO |
[Glucose co-treated with Deferoxamine] results in increased expression of OPA1 mRNA; Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of OPA1 mRNA] Deferoxamine results in increased expression of OPA1 mRNA |
CTD |
PMID:33962019 |
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NCBI chr11:71,108,100...71,185,170
Ensembl chr11:71,109,873...71,185,109
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G |
P4ha1 |
prolyl 4-hydroxylase subunit alpha 1 |
decreases expression multiple interactions |
ISO |
Deferoxamine results in decreased expression of P4HA1 protein ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of P4HA1 protein] |
CTD |
PMID:19515424 |
|
NCBI chr20:27,302,046...27,352,098
Ensembl chr20:27,302,141...27,352,786
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G |
Parp1 |
poly (ADP-ribose) polymerase 1 |
increases cleavage multiple interactions |
ISO |
Deferoxamine results in increased cleavage of PARP1 protein Indomethacin promotes the reaction [Deferoxamine results in increased cleavage of PARP1 protein]; Sulindac promotes the reaction [Deferoxamine results in increased cleavage of PARP1 protein] |
CTD |
PMID:21882223 |
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NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
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G |
Pdgfa |
platelet derived growth factor subunit A |
multiple interactions |
EXP |
Deferoxamine inhibits the reaction [Asbestos, Amosite results in increased expression of PDGFA mRNA] |
CTD |
PMID:11306436 |
|
NCBI chr12:15,645,549...15,667,056
Ensembl chr12:15,645,541...15,666,497
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G |
Pdgfb |
platelet derived growth factor subunit B |
multiple interactions |
EXP |
Deferoxamine inhibits the reaction [PDGFB protein results in increased phosphorylation of AKT1 protein]; Deferoxamine inhibits the reaction [PDGFB protein results in increased phosphorylation of MAPK1 protein]; Deferoxamine inhibits the reaction [PDGFB protein results in increased phosphorylation of MAPK3 protein] |
CTD |
PMID:18032466 |
|
NCBI chr 7:111,539,444...111,557,984
Ensembl chr 7:111,540,345...111,557,984
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G |
Pdgfrb |
platelet derived growth factor receptor beta |
decreases expression |
EXP |
Deferoxamine results in decreased expression of PDGFRB protein |
CTD |
PMID:18032466 |
|
NCBI chr18:54,500,002...54,538,843
Ensembl chr18:54,499,964...54,538,843
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G |
Pdhb |
pyruvate dehydrogenase E1 subunit beta |
increases expression multiple interactions |
ISO |
Deferoxamine results in increased expression of PDHB protein ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of PDHB protein] |
CTD |
PMID:19515424 |
|
NCBI chr15:16,752,561...16,758,503
Ensembl chr15:16,750,980...16,758,500
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G |
Pdk1 |
pyruvate dehydrogenase kinase 1 |
increases expression |
ISO |
Deferoxamine results in increased expression of PDK1 mRNA |
CTD |
PMID:21558026 |
|
NCBI chr 3:56,705,824...56,733,040
Ensembl chr 3:56,705,871...56,733,038
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G |
Pfkfb4 |
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 |
multiple interactions |
ISO |
[Deferoxamine results in decreased abundance of Iron] which results in increased expression of PFKFB4 mRNA |
CTD |
PMID:16025159 |
|
NCBI chr 8:109,643,558...109,687,006
Ensembl chr 8:109,643,937...109,685,634
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G |
Pgk1 |
phosphoglycerate kinase 1 |
multiple interactions increases expression decreases expression |
ISO |
ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of PGK1 protein] Deferoxamine results in increased expression of PGK1 mRNA Deferoxamine results in decreased expression of PGK1 protein |
CTD |
PMID:19515424 PMID:34998824 |
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NCBI chr X:71,271,454...71,287,429
Ensembl chr X:71,271,440...71,287,418
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G |
Pik3r1 |
phosphoinositide-3-kinase regulatory subunit 1 |
multiple interactions |
ISO |
[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of PIK3R1 mRNA; MIR184 mRNA inhibits the reaction [[Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of PIK3R1 mRNA] |
CTD |
PMID:35690295 |
|
NCBI chr 2:32,878,942...32,963,611
Ensembl chr 2:32,882,032...32,963,631
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G |
Pink1 |
PTEN induced kinase 1 |
multiple interactions |
ISO |
[Glucose co-treated with Deferoxamine] results in increased expression of PINK1 mRNA; Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of PINK1 mRNA] |
CTD |
PMID:33962019 |
|
NCBI chr 5:150,530,523...150,542,635
Ensembl chr 5:150,530,523...150,542,635
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G |
Plagl2 |
PLAG1 like zinc finger 2 |
multiple interactions |
ISO |
Deferoxamine results in increased expression of and affects the localization of PLAGL2 protein |
CTD |
PMID:11832486 |
|
NCBI chr 3:141,695,322...141,708,567
Ensembl chr 3:141,695,322...141,708,503
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G |
Plau |
plasminogen activator, urokinase |
multiple interactions |
ISO |
Deferoxamine inhibits the reaction [ferric nitrilotriacetate results in increased activity of PLAU mRNA]; Deferoxamine inhibits the reaction [ferric nitrilotriacetate results in increased expression of PLAU mRNA] |
CTD |
PMID:17571974 |
|
NCBI chr15:3,456,230...3,462,732
Ensembl chr15:3,456,232...3,462,775
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G |
Plin2 |
perilipin 2 |
multiple interactions |
ISO |
[Paclitaxel co-treated with FV-429 compound co-treated with Deferoxamine] promotes the reaction [Oxygen deficiency results in increased expression of PLIN2 protein]; Deferoxamine promotes the reaction [Oxygen deficiency results in increased expression of PLIN2 protein] |
CTD |
PMID:34648812 |
|
NCBI chr 5:101,156,643...101,211,738
Ensembl chr 5:101,154,411...101,242,319
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G |
Pmaip1 |
phorbol-12-myristate-13-acetate-induced protein 1 |
increases expression multiple interactions |
ISO |
Deferoxamine results in increased expression of PMAIP1 mRNA [Glucose co-treated with Deferoxamine] results in increased expression of PMAIP1 mRNA; Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of PMAIP1 mRNA] |
CTD |
PMID:33962019 |
|
NCBI chr18:59,986,187...59,990,174
Ensembl chr18:59,986,017...59,992,429
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G |
Pmp22 |
peripheral myelin protein 22 |
multiple interactions |
ISO |
[Deferoxamine results in decreased abundance of Iron] which results in decreased expression of PMP22 mRNA |
CTD |
PMID:12393473 |
|
NCBI chr10:47,795,709...47,825,715
Ensembl chr10:47,795,709...47,825,714
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G |
Ppia |
peptidylprolyl isomerase A |
multiple interactions decreases expression |
ISO |
ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of PPIA protein] Deferoxamine results in decreased expression of PPIA protein |
CTD |
PMID:19515424 |
|
NCBI chr14:81,279,292...81,282,960
Ensembl chr14:81,275,091...81,299,601
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G |
Prkcd |
protein kinase C, delta |
increases phosphorylation |
ISO |
Deferoxamine results in increased phosphorylation of PRKCD protein |
CTD |
PMID:17097691 |
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NCBI chr16:5,769,226...5,807,214
Ensembl chr16:5,769,215...5,799,352
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G |
Ptgs2 |
prostaglandin-endoperoxide synthase 2 |
increases stability increases expression multiple interactions |
ISO |
Deferoxamine results in increased stability of PTGS2 protein Deferoxamine results in increased expression of PTGS2 mRNA; Deferoxamine results in increased expression of PTGS2 protein 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Deferoxamine results in increased expression of PTGS2 protein]; [Sulindac co-treated with Deferoxamine] results in increased expression of PTGS2 protein; ferric citrate inhibits the reaction [Deferoxamine results in increased expression of PTGS2 protein]; Indomethacin promotes the reaction [Deferoxamine results in increased expression of PTGS2 protein]; TP53 gene mutant form promotes the reaction [Deferoxamine results in increased expression of PTGS2 protein] 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Deferoxamine results in increased expression of PTGS2 protein]; Deferoxamine inhibits the reaction [Benzene results in increased expression of PTGS2 mRNA]; ferric citrate inhibits the reaction [Deferoxamine results in increased expression of PTGS2 protein] |
CTD |
PMID:16527254 PMID:21882223 PMID:32816093 PMID:35661779 |
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NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
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G |
Rack1 |
receptor for activated C kinase 1 |
decreases expression multiple interactions |
ISO |
Deferoxamine results in decreased expression of RACK1 protein ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of RACK1 protein] |
CTD |
PMID:19515424 |
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NCBI chr10:33,169,415...33,174,896
Ensembl chr10:33,169,169...33,174,975
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G |
Ramp2 |
receptor activity modifying protein 2 |
decreases expression |
ISO |
Deferoxamine results in decreased expression of RAMP2 mRNA |
CTD |
PMID:11754965 |
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NCBI chr10:86,187,366...86,190,692
Ensembl chr10:86,188,812...86,231,829
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G |
Rb1 |
RB transcriptional corepressor 1 |
decreases phosphorylation |
ISO |
Deferoxamine results in decreased phosphorylation of RB1 protein |
CTD |
PMID:11468187 |
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NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302
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G |
Runx2 |
RUNX family transcription factor 2 |
decreases expression |
ISO |
Deferoxamine results in decreased expression of RUNX2 mRNA |
CTD |
PMID:16772336 |
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NCBI chr 9:16,167,504...16,492,826
Ensembl chr 9:16,167,482...16,492,167
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G |
Sag |
S-antigen visual arrestin |
multiple interactions |
EXP |
Deferoxamine inhibits the reaction [SAG results in increased abundance of Free Radicals] |
CTD |
PMID:8407215 |
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NCBI chr 9:88,467,797...88,508,821
Ensembl chr 9:88,469,376...88,508,820
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G |
Sdhb |
succinate dehydrogenase complex iron sulfur subunit B |
decreases expression |
ISO |
Deferoxamine results in decreased expression of SDHB protein |
CTD |
PMID:31238089 |
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NCBI chr 5:153,264,906...153,285,570
Ensembl chr 5:153,264,899...153,314,293
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G |
Sele |
selectin E |
multiple interactions |
ISO |
[Deferoxamine affects the abundance of Iron] inhibits the reaction [TNF protein results in increased expression of SELE mRNA]; [Deferoxamine affects the abundance of Iron] inhibits the reaction [TNF protein results in increased expression of SELE protein] |
CTD |
PMID:12633744 |
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NCBI chr13:76,402,841...76,412,741
Ensembl chr13:76,403,304...76,412,741
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G |
Sesn2 |
sestrin 2 |
multiple interactions |
ISO |
Deferoxamine inhibits the reaction [erastin results in increased expression of SESN2 protein] |
CTD |
PMID:31323261 |
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NCBI chr 5:144,702,287...144,721,241
Ensembl chr 5:144,701,530...144,721,260
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G |
Setd1a |
SET domain containing 1A, histone lysine methyltransferase |
increases expression |
ISO |
Deferoxamine results in increased expression of SETD1A mRNA |
CTD |
PMID:23483119 |
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NCBI chr 1:182,386,197...182,411,695
Ensembl chr 1:182,388,060...182,411,090
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G |
Setd2 |
SET domain containing 2, histone lysine methyltransferase |
increases expression affects expression |
ISO |
Deferoxamine results in increased expression of SETD2 mRNA Deferoxamine affects the expression of SETD2 mRNA |
CTD |
PMID:23483119 |
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NCBI chr 8:110,511,808...110,597,489
Ensembl chr 8:110,511,772...110,597,489
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G |
Sirt1 |
sirtuin 1 |
increases expression |
ISO |
Deferoxamine results in increased expression of SIRT1 protein |
CTD |
PMID:22245592 |
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NCBI chr20:25,307,143...25,329,260
Ensembl chr20:25,306,917...25,329,260
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G |
Slc11a2 |
solute carrier family 11 member 2 |
multiple interactions decreases expression increases expression |
EXP ISO |
[Deferoxamine co-treated with Manganese] results in increased expression of SLC11A2; [Deferoxamine promotes the reaction [Doxorubicin results in increased expression of SLC11A2 protein]] which results in increased uptake of Copper; Deferoxamine promotes the reaction [Doxorubicin results in increased expression of SLC11A2 mRNA]; Deferoxamine promotes the reaction [Doxorubicin results in increased expression of SLC11A2 protein] Deferoxamine results in decreased expression of SLC11A2 mRNA Deferoxamine results in increased expression of SLC11A2 protein [Deferoxamine results in decreased abundance of Iron] which results in increased expression of SLC11A2 mRNA; [Deferoxamine results in increased expression of SLC11A2 protein] which results in increased uptake of Manganese; Deferoxamine promotes the reaction [Deferoxamine results in increased expression of SLC11A2 protein] |
CTD |
PMID:11933051 PMID:12393473 PMID:23764342 PMID:24089420 |
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NCBI chr 7:131,503,076...131,540,246
Ensembl chr 7:131,503,081...131,540,145
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G |
Slc19a2 |
solute carrier family 19 member 2 |
decreases expression |
ISO |
Deferoxamine results in decreased expression of SLC19A2 mRNA |
CTD |
PMID:34998824 |
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NCBI chr13:76,601,975...76,616,175
Ensembl chr13:76,601,900...76,616,172
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