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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:ionophore
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Accession:CHEBI:24869 term browser browse the term
Definition:A compound which can carry specific ions through membranes of cells or organelles.
Synonyms:related_synonym: ionophores
 xref: Wikipedia:Ionophore



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(S,S,S)-nicotianamine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace angiotensin I converting enzyme decreases activity ISO nicotianamine results in decreased activity of ACE protein CTD PMID:26106051 NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131
JBrowse link
G Ace2 angiotensin I converting enzyme 2 decreases activity ISO nicotianamine results in decreased activity of ACE2 protein CTD PMID:26106051 NCBI chr  X:30,293,597...30,340,961
Ensembl chr  X:30,293,589...30,340,977
JBrowse link
alborixin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2 associated X, apoptosis regulator increases expression ISO alborixin results in increased expression of BAX protein CTD PMID:27378626 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO alborixin results in decreased expression of BCL2 protein CTD PMID:27378626 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Casp3 caspase 3 increases cleavage ISO alborixin results in increased cleavage of CASP3 protein CTD PMID:27378626 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp8 caspase 8 increases activity ISO alborixin results in increased activity of CASP8 protein CTD PMID:27378626 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Casp9 caspase 9 increases activity ISO alborixin results in increased activity of CASP9 protein CTD PMID:27378626 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage ISO alborixin results in increased cleavage of PARP1 protein CTD PMID:27378626 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
bafilomycin A1 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agt angiotensinogen multiple interactions EXP bafilomycin A1 inhibits the reaction [AGT protein affects the localization of Calcium] CTD PMID:21613610 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977
JBrowse link
G Aim2 absent in melanoma 2 multiple interactions ISO [bafilomycin A1 co-treated with [sodium arsenite results in increased abundance of Arsenic]] results in increased expression of AIM2 protein CTD PMID:32645460 NCBI chr13:85,865,206...85,906,996
Ensembl chr13:85,866,284...85,906,975
JBrowse link
G Akt1s1 AKT1 substrate 1 multiple interactions EXP bafilomycin A1 inhibits the reaction [EGF protein results in increased phosphorylation of AKT1S1 protein] CTD PMID:22689575 NCBI chr 1:95,333,186...95,339,678
Ensembl chr 1:95,332,898...95,339,677
JBrowse link
G Alb albumin decreases uptake ISO bafilomycin A1 results in decreased uptake of ALB protein CTD PMID:16313995 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 increases expression ISO bafilomycin A1 results in increased expression of APAF1 protein CTD PMID:28483490 NCBI chr 7:25,494,143...25,579,540
Ensembl chr 7:25,494,609...25,579,540
JBrowse link
G Appl1 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 multiple interactions ISO bafilomycin A1 promotes the reaction [Lipopolysaccharides results in increased degradation of APPL1 protein]; bafilomycin A1 promotes the reaction [Poly I-C results in increased degradation of APPL1 protein] CTD PMID:25780039 NCBI chr16:2,118,503...2,166,741
Ensembl chr16:2,121,255...2,166,692
JBrowse link
G Asic1 acid sensing ion channel subunit 1 multiple interactions ISO bafilomycin A1 inhibits the reaction [Freund's Adjuvant results in increased expression of ASIC1 mRNA] CTD PMID:16769263 NCBI chr 7:130,798,317...130,828,535
Ensembl chr 7:130,799,917...130,828,541
JBrowse link
G Atg5 autophagy related 5 multiple interactions ISO ATG5 protein affects the reaction [bafilomycin A1 promotes the reaction [gossypol acetic acid results in increased expression of MAP1LC3B protein modified form]] CTD PMID:29938581 NCBI chr20:47,798,222...47,889,216
Ensembl chr20:47,798,290...47,889,209
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO bafilomycin A1 inhibits the reaction [Hydroxychloroquine results in increased activity of BAX protein] CTD PMID:12813466 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO bafilomycin A1 results in decreased expression of BCL2 mRNA CTD PMID:31310755 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Becn1 beclin 1 multiple interactions
increases expression
ISO
EXP
bafilomycin A1 inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of BECN1 protein]
[Swainsonine co-treated with bafilomycin A1] results in increased expression of BECN1 protein; bafilomycin A1 promotes the reaction [[lead acetate results in increased abundance of Lead] which results in increased expression of BECN1 protein]
bafilomycin A1 results in increased expression of BECN1 protein
CTD PMID:32645460 PMID:33186601 PMID:33242459 NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742
JBrowse link
G Bglap bone gamma-carboxyglutamate protein multiple interactions ISO bafilomycin A1 inhibits the reaction [[Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid] results in increased expression of BGLAP mRNA] CTD PMID:23111315 NCBI chr 2:173,838,518...173,839,495
Ensembl chr 2:173,838,518...173,839,495
JBrowse link
G Bid BH3 interacting domain death agonist multiple interactions
increases cleavage
increases expression
EXP
ISO
bafilomycin A1 inhibits the reaction [manganese chloride results in increased expression of BID protein modified form]; bafilomycin A1 inhibits the reaction [manganese chloride results in increased expression of BID protein]
vistusertib affects the reaction [bafilomycin A1 results in increased cleavage of BID protein]
bafilomycin A1 results in increased expression of BID protein modified form
CTD PMID:26853465 PMID:28378122 NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720
JBrowse link
G Bnip3 BCL2 interacting protein 3 increases expression
multiple interactions
ISO bafilomycin A1 results in increased expression of BNIP3 mRNA; bafilomycin A1 results in increased expression of BNIP3 protein
BNIP3 mutant form promotes the reaction [bafilomycin A1 results in increased cleavage of PARP1 protein]; capivasertib affects the reaction [bafilomycin A1 results in increased expression of BNIP3 protein]; Erlotinib Hydrochloride inhibits the reaction [bafilomycin A1 results in increased expression of BNIP3 protein]; Gefitinib inhibits the reaction [bafilomycin A1 results in increased expression of BNIP3 protein]; HIF1A mutant form inhibits the reaction [bafilomycin A1 results in increased expression of BNIP3 mRNA]; Lapatinib inhibits the reaction [bafilomycin A1 results in increased expression of BNIP3 mRNA]; vistusertib inhibits the reaction [bafilomycin A1 results in increased expression of BNIP3 protein]
CTD PMID:25981168 PMID:26853465 NCBI chr 1:193,708,164...193,725,348
Ensembl chr 1:193,708,167...193,725,359
JBrowse link
G Casp3 caspase 3 decreases activity
increases cleavage
multiple interactions
increases activity
ISO
EXP
bafilomycin A1 results in decreased activity of CASP3 protein
bafilomycin A1 results in increased cleavage of CASP3 protein
bafilomycin A1 inhibits the reaction [Cadmium results in increased cleavage of CASP3 protein]
bafilomycin A1 results in increased activity of CASP3 protein
[Swainsonine co-treated with bafilomycin A1] results in increased cleavage of CASP3 protein; bafilomycin A1 inhibits the reaction [manganese chloride results in increased cleavage of CASP3 protein]; bafilomycin A1 promotes the reaction [Hydrogen Peroxide results in increased expression of CASP3 protein modified form]
[bafilomycin A1 co-treated with Cannabidiol] results in increased cleavage of CASP3 protein; [bafilomycin A1 co-treated with cobaltous chloride co-treated with TP53 gene mutant form] results in increased activity of CASP3 protein; [bafilomycin A1 co-treated with methanandamide] results in increased cleavage of CASP3 protein; [Cannabidiol co-treated with bafilomycin A1] results in increased cleavage of CASP3 protein; bafilomycin A1 inhibits the reaction [Soot analog results in increased expression of CASP3 protein]; bafilomycin A1 inhibits the reaction [tetrandrine results in increased cleavage of CASP3 protein]; bafilomycin A1 promotes the reaction [Atorvastatin results in increased cleavage of CASP3 protein]; bafilomycin A1 promotes the reaction [brazilin results in increased activity of CASP3 protein]; bafilomycin A1 promotes the reaction [fosbretabulin results in increased cleavage of CASP3 protein]; tin protoporphyrin IX inhibits the reaction [[bafilomycin A1 co-treated with Cannabidiol] results in increased cleavage of CASP3 protein]; tin protoporphyrin IX inhibits the reaction [[bafilomycin A1 co-treated with methanandamide] results in increased cleavage of CASP3 protein]; vistusertib affects the reaction [bafilomycin A1 results in increased cleavage of CASP3 protein]
CTD PMID:20876807 PMID:23380477 PMID:24321340 PMID:24889822 PMID:25266202 More... NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp4 caspase 4 increases activity ISO bafilomycin A1 results in increased activity of CASP4 protein CTD PMID:20371669 NCBI chr 8:2,599,017...2,635,097
Ensembl chr 8:2,598,876...2,635,092
JBrowse link
G Casp7 caspase 7 increases activity
decreases activity
ISO bafilomycin A1 results in increased activity of CASP7 protein
bafilomycin A1 results in decreased activity of CASP7 protein
CTD PMID:20371669 PMID:25981168 NCBI chr 1:255,437,195...255,476,737
Ensembl chr 1:255,437,172...255,476,729
JBrowse link
G Casp8 caspase 8 multiple interactions EXP
ISO
bafilomycin A1 inhibits the reaction [manganese chloride results in increased cleavage of CASP8 protein]
bafilomycin A1 inhibits the reaction [Cadmium results in increased cleavage of CASP8 protein]
CTD PMID:28378122 PMID:29111403 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Casp9 caspase 9 multiple interactions EXP
ISO
bafilomycin A1 inhibits the reaction [manganese chloride results in increased cleavage of CASP9 protein]
bafilomycin A1 inhibits the reaction [Soot analog results in increased expression of CASP9 protein]
CTD PMID:28378122 PMID:30240709 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Ccnd1 cyclin D1 multiple interactions ISO bafilomycin A1 inhibits the reaction [Dexamethasone results in decreased expression of CCND1 protein] CTD PMID:33359579 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Cdc25c cell division cycle 25C multiple interactions ISO bafilomycin A1 inhibits the reaction [xanthatin results in decreased stability of CDC25C protein] CTD PMID:29074359 NCBI chr18:26,335,156...26,356,199
Ensembl chr18:26,335,834...26,356,185
JBrowse link
G Ctsb cathepsin B multiple interactions ISO bafilomycin A1 inhibits the reaction [[cobaltous chloride co-treated with TP53 gene mutant form] results in increased activity of CTSB protein]; bafilomycin A1 inhibits the reaction [Hydroxychloroquine affects the localization of CTSB protein] CTD PMID:12813466 PMID:23380477 NCBI chr15:37,389,636...37,410,508
Ensembl chr15:37,389,629...37,410,500
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 multiple interactions ISO bafilomycin A1 inhibits the reaction [CpG ODN 2216 results in increased expression of CXCL10 protein]; bafilomycin A1 inhibits the reaction [gardiquimod results in increased expression of CXCL10 protein]; bafilomycin A1 inhibits the reaction [Poly I-C results in increased expression of CXCL10 protein] CTD PMID:26682054 NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975
JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 increases expression
multiple interactions
EXP bafilomycin A1 results in increased expression of DDIT4 protein
[EGF protein co-treated with bafilomycin A1] results in increased expression of DDIT4 protein
CTD PMID:22689575 NCBI chr20:27,891,989...27,894,088
Ensembl chr20:27,891,998...27,894,105
JBrowse link
G Egf epidermal growth factor multiple interactions EXP [bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Arginine; [bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Asparagine; [bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Isoleucine; [bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Leucine; [bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Lysine; [bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Methionine; [bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Ornithine; [bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Phenylalanine; [bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Tyrosine; [bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Valine; [bafilomycin A1 co-treated with EGF protein] results in increased abundance of Aspartic Acid; [bafilomycin A1 co-treated with EGF protein] results in increased abundance of Taurine; [EGF protein co-treated with bafilomycin A1] results in increased expression of DDIT4 protein; bafilomycin A1 inhibits the reaction [EGF protein results in increased activity of and results in increased phosphorylation of RPS6KB1 protein]; bafilomycin A1 inhibits the reaction [EGF protein results in increased phosphorylation of AKT1S1 protein]; bafilomycin A1 inhibits the reaction [EGF protein results in increased phosphorylation of EIF4EBP1 protein]; Cycloheximide inhibits the reaction [[bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Arginine]; Cycloheximide inhibits the reaction [[bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Asparagine]; Cycloheximide inhibits the reaction [[bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Isoleucine]; Cycloheximide inhibits the reaction [[bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Leucine]; Cycloheximide inhibits the reaction [[bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Lysine]; Cycloheximide inhibits the reaction [[bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Methionine]; Cycloheximide inhibits the reaction [[bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Ornithine]; Cycloheximide inhibits the reaction [[bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Phenylalanine]; Cycloheximide inhibits the reaction [[bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Tyrosine]; Cycloheximide inhibits the reaction [[bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Valine] CTD PMID:22689575 NCBI chr 2:218,219,408...218,302,370
Ensembl chr 2:218,219,415...218,302,064
JBrowse link
G Egfr epidermal growth factor receptor multiple interactions ISO bafilomycin A1 inhibits the reaction [Arsenic Trioxide results in decreased expression of EGFR protein] CTD PMID:30237564 NCBI chr14:91,176,931...91,349,722
Ensembl chr14:91,177,067...91,344,382
JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 multiple interactions EXP bafilomycin A1 inhibits the reaction [EGF protein results in increased phosphorylation of EIF4EBP1 protein]; bafilomycin A1 inhibits the reaction [INS protein results in increased phosphorylation of EIF4EBP1 protein] CTD PMID:22689575 NCBI chr16:64,792,595...64,805,984
Ensembl chr16:64,790,226...64,805,984
JBrowse link
G Epor erythropoietin receptor multiple interactions ISO bafilomycin A1 inhibits the reaction [Aristolochic Acids results in increased degradation of and results in decreased expression of EPOR protein] CTD PMID:26136230 NCBI chr 8:20,489,678...20,494,257
Ensembl chr 8:20,489,678...20,494,257
JBrowse link
G Faslg Fas ligand multiple interactions ISO
EXP
bafilomycin A1 inhibits the reaction [FASL protein affects the localization of Calcium]
bafilomycin A1 inhibits the reaction [manganese chloride results in increased expression of FASLG protein]
CTD PMID:20200208 PMID:28378122 NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215
JBrowse link
G Fmc1 formation of mitochondrial complex V assembly factor 1 multiple interactions ISO bafilomycin A1 inhibits the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone results in decreased expression of FMC1 protein] CTD PMID:29371327 NCBI chr 4:67,274,104...67,282,140
Ensembl chr 4:67,274,104...67,282,140
JBrowse link
G Foxo1 forkhead box O1 multiple interactions EXP bafilomycin A1 inhibits the reaction [resveratrol inhibits the reaction [Hydrogen Peroxide results in increased acetylation of FOXO1 protein]] CTD PMID:24889822 NCBI chr 2:136,312,168...136,390,603
Ensembl chr 2:136,312,168...136,387,790
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha increases expression
multiple interactions
ISO bafilomycin A1 results in increased expression of HIF1A protein
HIF1A mutant form inhibits the reaction [bafilomycin A1 results in increased expression of BNIP3 mRNA]; HIF1A mutant form promotes the reaction [bafilomycin A1 results in increased cleavage of PARP1 protein]; lapatinib inhibits the reaction [bafilomycin A1 results in increased expression of HIF1A protein]
CTD PMID:25981168 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
JBrowse link
G Hmox1 heme oxygenase 1 decreases expression
multiple interactions
ISO bafilomycin A1 results in decreased expression of HMOX1 protein
[bafilomycin A1 co-treated with methanandamide] results in increased expression of HMOX1 protein; [bafilomycin A1 co-treated with tin protoporphyrin IX] promotes the reaction [Cannabidiol results in increased expression of HMOX1 protein]; bafilomycin A1 inhibits the reaction [4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole results in increased expression of HMOX1 protein]
CTD PMID:29796178 PMID:33076330 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Ifng interferon gamma decreases expression ISO bafilomycin A1 results in decreased expression of IFNG mRNA CTD PMID:16932910 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Il1b interleukin 1 beta decreases expression
multiple interactions
ISO bafilomycin A1 results in decreased expression of IL1B mRNA
[bafilomycin A1 co-treated with [sodium arsenite results in increased abundance of Arsenic]] results in increased expression of IL1B protein; bafilomycin A1 inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with aluminum sulfate] results in increased secretion of IL1B protein]
CTD PMID:16932910 PMID:24158569 PMID:32645460 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il6 interleukin 6 increases expression ISO bafilomycin A1 results in increased expression of IL6 mRNA CTD PMID:16932910 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Ins2 insulin 2 multiple interactions EXP
ISO
bafilomycin A1 inhibits the reaction [INS protein results in increased phosphorylation of EIF4EBP1 protein]; bafilomycin A1 inhibits the reaction [INS protein results in increased phosphorylation of RPS6KB1 protein]
bafilomycin A1 promotes the reaction [Palmitic Acid inhibits the reaction [INS1 protein results in increased uptake of 2-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose]]
CTD PMID:22689575 PMID:32283200 NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775
JBrowse link
G Lrrk2 leucine-rich repeat kinase 2 increases response to substance ISO LRRK2 gene mutant form results in increased susceptibility to bafilomycin A1 CTD PMID:25017139 NCBI chr 7:122,826,712...122,987,711
Ensembl chr 7:122,826,696...122,987,703
JBrowse link
G Map1lc3a microtubule-associated protein 1 light chain 3 alpha multiple interactions
increases expression
ISO bafilomycin A1 promotes the reaction [Uranium results in increased expression of MAP1LC3A protein]
bafilomycin A1 results in increased expression of MAP1LC3A protein modified form
CTD PMID:30871063 PMID:31120128 NCBI chr 3:143,783,024...143,784,670
Ensembl chr 3:143,783,024...143,784,670
JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta multiple interactions
increases lipidation
increases expression
increases cleavage
decreases degradation
ISO
EXP
[bafilomycin A1 co-treated with Miconazole] results in increased expression of MAP1LC3B protein; [di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone co-treated with bafilomycin A1] results in increased expression of MAP1LC3B mRNA; [TNF protein co-treated with bafilomycin A1] results in increased expression of MAP1LC3B protein alternative form; Acetylcysteine inhibits the reaction [di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone promotes the reaction [bafilomycin A1 results in increased expression of MAP1LC3B protein]]; ATG5 protein affects the reaction [bafilomycin A1 promotes the reaction [gossypol acetic acid results in increased expression of MAP1LC3B protein modified form]]; bafilomycin A1 affects the reaction [Ammonium Chloride results in increased metabolism of MAP1LC3B protein]; bafilomycin A1 affects the reaction [AZD4547 affects the expression of MAP1LC3B protein modified form]; bafilomycin A1 affects the reaction [AZD8186 affects the expression of MAP1LC3B protein modified form]; bafilomycin A1 inhibits the reaction [Chloroquine results in increased lipidation of MAP1LC3B protein]; bafilomycin A1 promotes the reaction [capivasertib results in increased expression of MAP1LC3B protein modified form]; bafilomycin A1 promotes the reaction [ginsenoside Rg2 results in increased expression of MAP1LC3B protein modified form]; bafilomycin A1 promotes the reaction [gossypol acetic acid results in increased expression of MAP1LC3B protein modified form]; bafilomycin A1 promotes the reaction [metarrestin results in increased expression of MAP1LC3B protein modified form]; bafilomycin A1 promotes the reaction [Miconazole results in increased lipidation of MAP1LC3B protein]; bafilomycin A1 promotes the reaction [Resveratrol results in increased expression of MAP1LC3B protein alternative form]; bafilomycin A1 promotes the reaction [vistusertib results in increased expression of MAP1LC3B protein modified form]; di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone promotes the reaction [bafilomycin A1 results in increased expression of MAP1LC3B protein]; Resveratrol promotes the reaction [[TNF protein co-treated with bafilomycin A1] results in increased expression of MAP1LC3B protein alternative form]
bafilomycin A1 results in increased lipidation of MAP1LC3B protein
[Doxorubicin co-treated with bafilomycin A1] results in increased expression of MAP1LC3B protein; [Glycyrrhizic Acid co-treated with bafilomycin A1] results in increased lipidation of MAP1LC3B protein; bafilomycin A1 promotes the reaction [C1QTNF9 protein results in increased expression of MAP1LC3B protein modified form]
bafilomycin A1 results in increased expression of MAP1LC3B protein modified form
bafilomycin A1 promotes the reaction [Triiodothyronine results in increased lipidation of MAP1LC3B protein]; Triiodothyronine promotes the reaction [bafilomycin A1 results in increased lipidation of MAP1LC3B protein]
bafilomycin A1 results in increased cleavage of MAP1LC3B protein
bafilomycin A1 results in decreased degradation of MAP1LC3B protein modified form
bafilomycin A1 results in increased expression of MAP1LC3B protein; bafilomycin A1 results in increased expression of MAP1LC3B protein alternative form; bafilomycin A1 results in increased expression of MAP1LC3B protein modified form
CTD PMID:23880069 PMID:24145604 PMID:25301941 PMID:26459185 PMID:26853465 More... NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
increases expression
ISO bafilomycin A1 inhibits the reaction [Capsaicin results in increased activity of MAPK1 protein]; bafilomycin A1 inhibits the reaction [Iron Compounds results in increased expression of MAPK1 protein modified form]; bafilomycin A1 promotes the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased phosphorylation of MAPK1 protein]
bafilomycin A1 results in increased expression of MAPK1 protein modified form
CTD PMID:20371669 PMID:28483490 PMID:32645460 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
increases expression
ISO bafilomycin A1 inhibits the reaction [Capsaicin results in increased activity of MAPK3 protein]; bafilomycin A1 inhibits the reaction [Iron Compounds results in increased expression of MAPK3 protein modified form]; bafilomycin A1 promotes the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased phosphorylation of MAPK3 protein]
bafilomycin A1 results in increased expression of MAPK3 protein modified form
CTD PMID:20371669 PMID:28483490 PMID:32645460 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 increases phosphorylation ISO bafilomycin A1 results in increased phosphorylation of MAPK8 protein CTD PMID:31310755 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
JBrowse link
G Mtor mechanistic target of rapamycin kinase decreases phosphorylation ISO bafilomycin A1 results in decreased phosphorylation of MTOR protein CTD PMID:31310755 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
JBrowse link
G Mttp microsomal triglyceride transfer protein increases expression ISO bafilomycin A1 results in increased expression of MTTP protein CTD PMID:34516972 NCBI chr 2:226,613,090...226,654,239
Ensembl chr 2:226,613,090...226,654,239
JBrowse link
G Ndrg1 N-myc downstream regulated 1 multiple interactions ISO NDRG1 protein results in decreased susceptibility to [di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone co-treated with bafilomycin A1] CTD PMID:24532803 NCBI chr 7:98,684,487...98,725,869
Ensembl chr 7:98,684,487...98,725,880
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions
increases expression
ISO bafilomycin A1 promotes the reaction [[Particulate Matter co-treated with Vitamin D] results in increased expression of NFE2L2 protein]; bafilomycin A1 promotes the reaction [[Silicon Dioxide co-treated with Vitamin D] results in increased expression of NFE2L2 protein]; bafilomycin A1 promotes the reaction [Particulate Matter results in increased expression of NFE2L2 protein]; bafilomycin A1 promotes the reaction [Silicon Dioxide results in increased expression of NFE2L2 protein]
bafilomycin A1 results in increased expression of NFE2L2 protein
CTD PMID:30698894 NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 multiple interactions
increases expression
ISO bafilomycin A1 inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of NLRP3 protein]
bafilomycin A1 results in increased expression of NLRP3 protein
CTD PMID:32645460 NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811
JBrowse link
G Nr5a1 nuclear receptor subfamily 5, group A, member 1 decreases expression ISO bafilomycin A1 results in decreased expression of NR5A1 protein CTD PMID:29524503 NCBI chr 3:22,464,786...22,486,328
Ensembl chr 3:22,465,502...22,486,328
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions
increases cleavage
increases expression
ISO bafilomycin A1 promotes the reaction [Atorvastatin results in increased cleavage of PARP1 protein]; bafilomycin A1 promotes the reaction [brazilin results in increased expression of PARP1 protein modified form]; bafilomycin A1 promotes the reaction [Flavanones results in increased cleavage of PARP1 protein]; bafilomycin A1 promotes the reaction [fosbretabulin results in increased cleavage of PARP1 protein]; BNIP3 mutant form promotes the reaction [bafilomycin A1 results in increased cleavage of PARP1 protein]; HIF1A mutant form promotes the reaction [bafilomycin A1 results in increased cleavage of PARP1 protein]
bafilomycin A1 inhibits the reaction [Cadmium results in increased cleavage of PARP1 protein]
bafilomycin A1 results in increased expression of PARP1 protein modified form
CTD PMID:20876807 PMID:21616090 PMID:24321340 PMID:25981168 PMID:28063998 More... NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Pcna proliferating cell nuclear antigen multiple interactions ISO bafilomycin A1 inhibits the reaction [Dexamethasone results in decreased expression of PCNA mRNA] CTD PMID:33359579 NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO bafilomycin A1 affects the localization of and results in increased activity of RELA protein CTD PMID:10339586 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Rps6kb1 ribosomal protein S6 kinase B1 decreases phosphorylation
multiple interactions
ISO
EXP
bafilomycin A1 results in decreased phosphorylation of RPS6KB1 protein
bafilomycin A1 inhibits the reaction [EGF protein results in increased activity of and results in increased phosphorylation of RPS6KB1 protein]; bafilomycin A1 inhibits the reaction [INS protein results in increased phosphorylation of RPS6KB1 protein]
CTD PMID:22689575 PMID:31310755 NCBI chr10:71,323,777...71,367,908
Ensembl chr10:71,323,777...71,367,908
JBrowse link
G Runx2 RUNX family transcription factor 2 multiple interactions ISO bafilomycin A1 inhibits the reaction [[Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid] results in increased expression of RUNX2 mRNA] CTD PMID:23111315 NCBI chr 9:16,167,504...16,492,826
Ensembl chr 9:16,167,482...16,492,167
JBrowse link
G Sirt1 sirtuin 1 multiple interactions EXP bafilomycin A1 inhibits the reaction [resveratrol inhibits the reaction [Hydrogen Peroxide results in decreased expression of SIRT1 protein]] CTD PMID:24889822 NCBI chr20:25,307,143...25,329,260
Ensembl chr20:25,306,917...25,329,260
JBrowse link
G Slc17a7 solute carrier family 17 member 7 multiple interactions EXP bafilomycin A1 inhibits the reaction [SLC17A7 protein results in increased uptake of Excitatory Amino Acid Agents]; bafilomycin A1 inhibits the reaction [SLC17A7 protein results in increased uptake of Zinc]; bafilomycin A1 inhibits the reaction [SLC30A3 protein promotes the reaction [SLC17A7 protein results in increased uptake of Zinc]] CTD PMID:15860731 NCBI chr 1:95,649,709...95,661,591
Ensembl chr 1:95,649,745...95,661,588
JBrowse link
G Slc30a3 solute carrier family 30 member 3 multiple interactions EXP bafilomycin A1 inhibits the reaction [SLC30A3 protein promotes the reaction [SLC17A7 protein results in increased uptake of Zinc]] CTD PMID:15860731 NCBI chr 6:25,264,310...25,284,720
Ensembl chr 6:25,275,528...25,284,720
JBrowse link
G Snai1 snail family transcriptional repressor 1 multiple interactions
increases expression
ISO bafilomycin A1 promotes the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of SNAI1 protein]
bafilomycin A1 results in increased expression of SNAI1 protein
CTD PMID:32645460 NCBI chr 3:156,248,479...156,252,969
Ensembl chr 3:156,248,485...156,252,969
JBrowse link
G Snca synuclein alpha multiple interactions
increases expression
ISO [bafilomycin A1 co-treated with Rotenone] results in increased expression of SNCA protein
bafilomycin A1 results in increased expression of SNCA protein
CTD PMID:26031332 NCBI chr 4:89,696,420...89,797,240
Ensembl chr 4:89,696,420...89,796,262
JBrowse link
G Sort1 sortilin 1 decreases expression ISO bafilomycin A1 results in decreased expression of SORT1 protein CTD PMID:25805502 NCBI chr 2:195,924,033...196,002,354
Ensembl chr 2:195,924,099...196,002,354
JBrowse link
G Sqstm1 sequestosome 1 increases expression
multiple interactions
ISO
EXP
bafilomycin A1 results in increased expression of SQSTM1 protein
bafilomycin A1 promotes the reaction [Hydrogen Peroxide results in increased expression of SQSTM1 protein]
[Resveratrol co-treated with bafilomycin A1] results in increased expression of SQSTM1 protein; [Silicon Dioxide co-treated with bafilomycin A1] results in increased expression of SQSTM1 protein; [Silicon Dioxide co-treated with Vitamin D co-treated with bafilomycin A1] results in increased expression of SQSTM1 protein; [TNF protein co-treated with bafilomycin A1] results in increased expression of SQSTM1 protein; [Vitamin D co-treated with bafilomycin A1] results in increased expression of SQSTM1 protein; bafilomycin A1 inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of SQSTM1 protein]; bafilomycin A1 inhibits the reaction [dactolisib results in decreased expression of SQSTM1 protein]; bafilomycin A1 inhibits the reaction [Dexamethasone results in decreased expression of SQSTM1 protein]; bafilomycin A1 inhibits the reaction [Resveratrol results in increased degradation of SQSTM1 protein]; bafilomycin A1 inhibits the reaction [Sorafenib results in decreased expression of SQSTM1 protein]; bafilomycin A1 promotes the reaction [ginsenoside Rg2 results in decreased expression of SQSTM1 protein]; bafilomycin A1 promotes the reaction [metarrestin results in decreased expression of SQSTM1 protein]; bafilomycin A1 promotes the reaction [Miconazole results in increased expression of SQSTM1 protein]; bafilomycin A1 promotes the reaction [N-Methyl-3,4-methylenedioxyamphetamine results in increased expression of SQSTM1 protein]; Fingolimod Hydrochloride affects the reaction [bafilomycin A1 results in increased expression of SQSTM1 protein]; sodium arsenite promotes the reaction [bafilomycin A1 results in increased expression of SQSTM1 protein]
[bafilomycin A1 co-treated with Rotenone] results in increased expression of SQSTM1 protein; bafilomycin A1 inhibits the reaction [Resveratrol inhibits the reaction [Streptozocin results in increased expression of SQSTM1 protein]]; bafilomycin A1 inhibits the reaction [Sirolimus results in decreased expression of SQSTM1 protein]; Streptozocin promotes the reaction [bafilomycin A1 results in increased expression of SQSTM1 protein]
CTD PMID:21778691 PMID:21858812 PMID:23151917 PMID:24145604 PMID:24238063 More... NCBI chr10:34,525,517...34,536,685
Ensembl chr10:34,525,519...34,536,673
JBrowse link
G Tbk1 TANK-binding kinase 1 multiple interactions ISO bafilomycin A1 promotes the reaction [Lipopolysaccharides results in increased phosphorylation of TBK1 protein]; bafilomycin A1 promotes the reaction [Poly I-C results in increased phosphorylation of TBK1 protein] CTD PMID:25780039 NCBI chr 7:57,077,830...57,110,868
Ensembl chr 7:57,077,830...57,110,892
JBrowse link
G Tlr8 toll-like receptor 8 multiple interactions ISO bafilomycin A1 inhibits the reaction [resiquimod results in increased activity of TLR8 protein] CTD PMID:21398612 NCBI chr  X:27,091,780...27,116,092
Ensembl chr  X:27,091,778...27,116,549
JBrowse link
G Tnf tumor necrosis factor increases expression
multiple interactions
ISO bafilomycin A1 results in increased expression of TNF mRNA
[TNF protein co-treated with bafilomycin A1] results in increased expression of MAP1LC3B protein alternative form; [TNF protein co-treated with bafilomycin A1] results in increased expression of SQSTM1 protein; resveratrol promotes the reaction [[TNF protein co-treated with bafilomycin A1] results in increased expression of MAP1LC3B protein alternative form]
CTD PMID:16932910 PMID:24145604 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tomm20 translocase of outer mitochondrial membrane 20 increases expression
multiple interactions
ISO bafilomycin A1 results in increased expression of TOMM20 protein
Triiodothyronine promotes the reaction [bafilomycin A1 results in increased expression of TOMM20 protein]
CTD PMID:30209975 NCBI chr19:54,925,197...54,935,188
Ensembl chr19:54,923,402...54,935,198
JBrowse link
G Tp53 tumor protein p53 multiple interactions ISO [bafilomycin A1 co-treated with cobaltous chloride co-treated with TP53 gene mutant form] results in increased activity of CASP3 protein; bafilomycin A1 inhibits the reaction [[cobaltous chloride co-treated with TP53 gene mutant form] results in increased activity of CTSB protein] CTD PMID:23380477 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Ulk1 unc-51 like autophagy activating kinase 1 multiple interactions EXP bafilomycin A1 affects the reaction [N-(1,3-benzodioxol-5-ylmethyl)-2,6-dichlorobenzamide affects the reaction [Glucose affects the phosphorylation of ULK1 protein]] CTD PMID:29128638 NCBI chr12:45,851,710...45,877,966
Ensembl chr12:45,851,710...45,877,966
JBrowse link
G Vdac1 voltage-dependent anion channel 1 multiple interactions
increases expression
ISO Triiodothyronine promotes the reaction [bafilomycin A1 results in increased expression of VDAC1 protein] CTD PMID:30209975 NCBI chr10:36,532,306...36,559,642
Ensembl chr10:36,532,244...36,559,640
JBrowse link
G Vdr vitamin D receptor multiple interactions ISO [bafilomycin A1 co-treated with Vitamin D] results in increased expression of VDR protein; [Silicon Dioxide co-treated with Vitamin D co-treated with bafilomycin A1] results in increased expression of VDR protein CTD PMID:30698894 NCBI chr 7:128,987,981...129,037,677
Ensembl chr 7:128,987,981...129,037,677
JBrowse link
G Vim vimentin multiple interactions
increases expression
ISO bafilomycin A1 promotes the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of VIM protein]
bafilomycin A1 results in increased expression of VIM protein
CTD PMID:32645460 NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187
JBrowse link
beauvericin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aatf apoptosis antagonizing transcription factor decreases expression ISO beauvericin results in decreased expression of AATF mRNA CTD PMID:29203277 NCBI chr10:69,299,029...69,392,207
Ensembl chr10:69,299,037...69,392,201
JBrowse link
G Abca1 ATP binding cassette subfamily A member 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of ABCA1 mRNA CTD PMID:31100301 NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170
JBrowse link
G Abcg1 ATP binding cassette subfamily G member 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of ABCG1 mRNA CTD PMID:31100301 NCBI chr20:9,126,687...9,182,948
Ensembl chr20:9,126,687...9,182,948
JBrowse link
G Acat2 acetyl-CoA acetyltransferase 2 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of ACAT2 protein CTD PMID:32407736 NCBI chr 1:47,695,833...47,713,879
Ensembl chr 1:47,695,788...47,752,821
JBrowse link
G Acin1 apoptotic chromatin condensation inducer 1 decreases expression ISO beauvericin results in decreased expression of ACIN1 mRNA CTD PMID:29203277 NCBI chr15:28,102,112...28,147,001
Ensembl chr15:28,102,112...28,147,001
JBrowse link
G Acsl4 acyl-CoA synthetase long-chain family member 4 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of ACSL4 protein CTD PMID:32407736 NCBI chr  X:105,942,794...106,006,573
Ensembl chr  X:105,942,799...106,006,427
JBrowse link
G Actb actin, beta decreases expression ISO beauvericin results in decreased expression of ACTB mRNA CTD PMID:29203277 NCBI chr12:11,663,112...11,666,697
Ensembl chr12:11,663,109...11,672,877
JBrowse link
G Aen apoptosis enhancing nuclease decreases expression ISO beauvericin results in decreased expression of AEN mRNA CTD PMID:29203277 NCBI chr 1:132,815,094...132,824,522
Ensembl chr 1:132,815,142...132,824,523
JBrowse link
G Aifm1 apoptosis inducing factor, mitochondria associated 1 decreases expression ISO beauvericin results in decreased expression of AIFM1 mRNA CTD PMID:29203277 NCBI chr  X:127,650,223...127,689,356
Ensembl chr  X:127,650,226...127,689,256
JBrowse link
G Ak4 adenylate kinase 4 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of AK4 mRNA CTD PMID:31100301 NCBI chr 5:116,039,222...116,099,064
Ensembl chr 5:116,039,616...116,098,618
JBrowse link
G Aldh5a1 aldehyde dehydrogenase 5 family, member A1 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of ALDH5A1 protein CTD PMID:32407736 NCBI chr17:40,132,339...40,158,677
Ensembl chr17:40,130,883...40,158,677
JBrowse link
G Aldoa aldolase, fructose-bisphosphate A decreases expression ISO beauvericin results in decreased expression of ALDOA mRNA CTD PMID:29203277 NCBI chr 1:181,402,275...181,407,476
Ensembl chr 1:181,402,275...181,406,182
JBrowse link
G Anapc13 anaphase promoting complex subunit 13 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of ANAPC13 protein CTD PMID:32407736 NCBI chr 8:103,205,520...103,213,936
Ensembl chr 8:103,205,520...103,213,936
JBrowse link
G Aprt adenine phosphoribosyl transferase decreases expression ISO beauvericin results in decreased expression of APRT mRNA CTD PMID:29203277 NCBI chr19:50,626,436...50,628,404
Ensembl chr19:50,626,202...50,628,431
JBrowse link
G Ar androgen receptor multiple interactions ISO beauvericin inhibits the reaction [Dihydrotestosterone results in increased expression of AR mRNA] CTD PMID:30716354 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925
JBrowse link
G Arhgdia Rho GDP dissociation inhibitor alpha decreases expression ISO beauvericin results in decreased expression of ARHGDIA mRNA CTD PMID:29203277 NCBI chr10:105,854,526...105,858,020
Ensembl chr10:105,854,533...105,858,023
JBrowse link
G Arpp21 cAMP regulated phosphoprotein 21 increases expression ISO beauvericin results in increased expression of ARPP21 mRNA CTD PMID:29203277 NCBI chr 8:112,034,636...112,199,273
Ensembl chr 8:112,034,642...112,194,297
JBrowse link
G Atp1a1 ATPase Na+/K+ transporting subunit alpha 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of ATP1A1 protein CTD PMID:32407736 NCBI chr 2:189,020,722...189,048,826
Ensembl chr 2:189,020,722...189,048,837
JBrowse link
G Atp1a3 ATPase Na+/K+ transporting subunit alpha 3 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of ATP1A3 protein CTD PMID:32407736 NCBI chr 1:80,572,790...80,601,936
Ensembl chr 1:80,572,796...80,601,918
JBrowse link
G Atp5pb ATP synthase peripheral stalk-membrane subunit b multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of ATP5PB protein CTD PMID:32407736 NCBI chr 2:193,424,138...193,435,418
Ensembl chr 2:193,424,047...193,435,418
JBrowse link
G Atp5pf ATP synthase peripheral stalk subunit F6 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of ATP5PF protein CTD PMID:32407736 NCBI chr11:23,881,594...23,889,581
Ensembl chr11:23,881,592...23,889,119
JBrowse link
G Bax BCL2 associated X, apoptosis regulator decreases expression
multiple interactions
ISO beauvericin results in decreased expression of BAX mRNA
[zearalenol co-treated with beauvericin] results in increased expression of BAX mRNA
CTD PMID:29203277 PMID:32956828 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator increases expression
multiple interactions
ISO beauvericin results in increased expression of BCL2 mRNA
[zearalenol co-treated with beauvericin] results in increased expression of BCL2 mRNA
CTD PMID:29203277 PMID:32956828 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Birc2 baculoviral IAP repeat-containing 2 increases expression ISO beauvericin results in increased expression of BIRC2 mRNA CTD PMID:29203277 NCBI chr 8:4,968,856...4,989,325
Ensembl chr 8:4,968,842...4,988,732
JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 increases expression ISO beauvericin results in increased expression of BIRC3 mRNA CTD PMID:29203277 NCBI chr 8:5,000,844...5,028,470
Ensembl chr 8:5,000,845...5,015,802
JBrowse link
G Btf3l4 basic transcription factor 3-like 4 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of BTF3L4 protein CTD PMID:32407736 NCBI chr 5:123,569,059...123,587,593
Ensembl chr 5:123,567,907...123,586,866
JBrowse link
G C1qtnf3 C1q and TNF related 3 decreases expression ISO beauvericin results in decreased expression of C1QTNF3 mRNA CTD PMID:29203277 NCBI chr 2:59,917,099...59,939,519
Ensembl chr 2:59,917,188...59,939,433
JBrowse link
G C1qtnf6 C1q and TNF related 6 increases expression ISO beauvericin results in increased expression of C1QTNF6 mRNA CTD PMID:29203277 NCBI chr 7:110,077,867...110,084,584
Ensembl chr 7:110,077,878...110,084,412
JBrowse link
G Caap1 caspase activity and apoptosis inhibitor 1 decreases expression ISO beauvericin results in decreased expression of CAAP1 mRNA CTD PMID:29203277 NCBI chr 5:109,313,253...109,414,323
Ensembl chr 5:109,361,912...109,414,314
JBrowse link
G Card11 caspase recruitment domain family, member 11 decreases expression ISO beauvericin results in decreased expression of CARD11 mRNA CTD PMID:29203277 NCBI chr12:13,620,979...13,758,115
Ensembl chr12:13,621,087...13,758,112
JBrowse link
G Casp3 caspase 3 increases activity
multiple interactions
EXP
ISO
beauvericin results in increased activity of CASP3 protein
[zearalenol co-treated with beauvericin] results in increased expression of CASP3 mRNA
CTD PMID:25178661 PMID:32956828 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp7 caspase 7 increases activity EXP beauvericin results in increased activity of CASP7 protein CTD PMID:25178661 NCBI chr 1:255,437,195...255,476,737
Ensembl chr 1:255,437,172...255,476,729
JBrowse link
G Casp8 caspase 8 increases expression ISO beauvericin results in increased expression of CASP8 mRNA CTD PMID:29203277 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Casp9 caspase 9 increases expression ISO beauvericin results in increased expression of CASP9 mRNA CTD PMID:29203277 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Ccar2 cell cycle and apoptosis regulator 2 decreases expression ISO beauvericin results in decreased expression of CCAR2 mRNA CTD PMID:29203277 NCBI chr15:45,212,797...45,228,001
Ensembl chr15:45,212,803...45,227,636
JBrowse link
G Ccdc124 coiled-coil domain containing 124 decreases expression ISO beauvericin results in decreased expression of CCDC124 mRNA CTD PMID:29203277 NCBI chr16:18,566,745...18,572,564
Ensembl chr16:18,566,745...18,572,564
JBrowse link
G Ccdc180 coiled-coil domain containing 180 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of CCDC180 protein CTD PMID:32407736 NCBI chr 5:60,154,883...60,223,508
Ensembl chr 5:60,154,910...60,223,522
JBrowse link
G Ccdc86 coiled-coil domain containing 86 decreases expression ISO beauvericin results in decreased expression of CCDC86 mRNA CTD PMID:29203277 NCBI chr 1:207,590,946...207,596,527
Ensembl chr 1:207,590,168...207,596,544
JBrowse link
G Ccng2 cyclin G2 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of CCNG2 mRNA CTD PMID:31100301 NCBI chr14:14,804,321...14,812,819
Ensembl chr14:14,804,322...14,812,830
JBrowse link
G Cct5 chaperonin containing TCP1 subunit 5 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of CCT5 protein CTD PMID:32407736 NCBI chr 2:82,591,750...82,602,903
Ensembl chr 2:82,590,630...82,602,930
JBrowse link
G Cd47 Cd47 molecule multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of CD47 protein CTD PMID:32407736 NCBI chr11:50,906,052...50,970,000
Ensembl chr11:50,906,177...50,969,425
JBrowse link
G Cd81 Cd81 molecule multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of CD81 protein CTD PMID:32407736 NCBI chr 1:198,235,861...198,251,660
Ensembl chr 1:198,241,484...198,251,660
JBrowse link
G Cdk2ap2 cyclin-dependent kinase 2 associated protein 2 decreases expression ISO beauvericin results in decreased expression of CDK2AP2 mRNA CTD PMID:29203277 NCBI chr 1:201,391,056...201,393,137
Ensembl chr 1:201,391,466...201,393,137
JBrowse link
G Cebpb CCAAT/enhancer binding protein beta multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of CEBPB mRNA CTD PMID:31100301 NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473
JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator increases expression ISO beauvericin results in increased expression of CFLAR mRNA CTD PMID:29203277 NCBI chr 9:60,185,338...60,236,173
Ensembl chr 9:60,185,452...60,237,034
JBrowse link
G Chchd2 coiled-coil-helix-coiled-coil-helix domain containing 2 decreases expression ISO beauvericin results in decreased expression of CHCHD2 mRNA CTD PMID:29203277 NCBI chr 9:94,500,439...94,501,110
Ensembl chr 9:94,500,432...94,501,128
JBrowse link
G Ciapin1 cytokine induced apoptosis inhibitor 1 decreases expression ISO beauvericin results in decreased expression of CIAPIN1 mRNA CTD PMID:29203277 NCBI chr19:10,179,963...10,195,511
Ensembl chr19:10,180,100...10,195,503
JBrowse link
G Cnp 2',3'-cyclic nucleotide 3' phosphodiesterase multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of CNP protein CTD PMID:32407736 NCBI chr10:85,511,164...85,517,723
Ensembl chr10:85,511,160...85,517,720
JBrowse link
G Coa6 cytochrome c oxidase assembly factor 6 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of COA6 protein CTD PMID:32407736 NCBI chr19:54,395,682...54,398,918
Ensembl chr19:54,395,742...54,399,407
JBrowse link
G Coro1c coronin 1C multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of CORO1C protein CTD PMID:32407736 NCBI chr12:42,712,960...42,785,179
Ensembl chr12:42,712,991...42,785,179
JBrowse link
G Cotl1 coactosin-like F-actin binding protein 1 decreases expression ISO beauvericin results in decreased expression of COTL1 mRNA CTD PMID:29203277 NCBI chr19:47,871,689...47,906,010
Ensembl chr19:47,871,694...47,911,689
JBrowse link
G Cplane2 ciliogenesis and planar polarity effector complex subunit 2 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of CPLANE2 protein CTD PMID:32407736 NCBI chr 5:153,515,507...153,516,455
Ensembl chr 5:153,515,376...153,522,508
JBrowse link
G Cpne1 copine 1 decreases expression ISO beauvericin results in decreased expression of CPNE1 mRNA CTD PMID:29203277 NCBI chr 3:144,587,548...144,629,603
Ensembl chr 3:144,588,995...144,598,636
JBrowse link
G Crim1 cysteine rich transmembrane BMP regulator 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of CRIM1 mRNA CTD PMID:31100301 NCBI chr 6:16,695,864...16,870,264
Ensembl chr 6:16,697,829...16,870,259
JBrowse link
G Csdc2 cold shock domain containing C2 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of CSDC2 protein CTD PMID:32407736 NCBI chr 7:113,451,998...113,466,464
Ensembl chr 7:113,451,998...113,466,463
JBrowse link
G Csk C-terminal Src kinase decreases expression ISO beauvericin results in decreased expression of CSK mRNA CTD PMID:29203277 NCBI chr 8:58,029,748...58,048,742
Ensembl chr 8:58,029,749...58,048,292
JBrowse link
G Ctps1 CTP synthase 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of CTPS1 protein CTD PMID:32407736 NCBI chr 5:134,125,022...134,154,155
Ensembl chr 5:134,125,025...134,154,180
JBrowse link
G Ctsd cathepsin D multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of CTSD protein CTD PMID:32407736 NCBI chr 1:197,527,467...197,539,343
Ensembl chr 1:197,527,467...197,539,488
JBrowse link
G Cyp4f39 cytochrome P450, family 4, subfamily f, polypeptide 39 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of CYP4F22 protein CTD PMID:32407736 NCBI chr 7:11,426,806...11,505,553
Ensembl chr 7:11,433,371...11,536,181
JBrowse link
G Dcxr dicarbonyl and L-xylulose reductase multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of DCXR protein CTD PMID:32407736 NCBI chr10:106,006,404...106,008,294 JBrowse link
G Ddias DNA damage-induced apoptosis suppressor decreases expression ISO beauvericin results in decreased expression of DDIAS mRNA CTD PMID:29203277 NCBI chr 1:146,906,150...146,930,462
Ensembl chr 1:146,906,154...146,930,462
JBrowse link
G Ddx47 DEAD-box helicase 47 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of DDX47 protein CTD PMID:32407736 NCBI chr 4:167,845,652...167,858,115
Ensembl chr 4:167,845,640...167,859,115
JBrowse link
G Dhrs7 dehydrogenase/reductase 7 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of DHRS7 protein CTD PMID:32407736 NCBI chr 6:91,332,259...91,347,856
Ensembl chr 6:91,251,323...91,347,892
JBrowse link
G Edem1 ER degradation enhancing alpha-mannosidase like protein 1 increases expression ISO beauvericin results in increased expression of EDEM1 mRNA CTD PMID:29203277 NCBI chr 4:141,797,631...141,829,717
Ensembl chr 4:141,797,701...141,829,717
JBrowse link
G Eif5a eukaryotic translation initiation factor 5A decreases expression ISO beauvericin results in decreased expression of EIF5A mRNA CTD PMID:29203277 NCBI chr10:54,640,104...54,644,845
Ensembl chr10:54,640,024...54,644,656
JBrowse link
G Faim2 Fas apoptotic inhibitory molecule 2 increases expression ISO beauvericin results in increased expression of FAIM2 mRNA CTD PMID:29203277 NCBI chr 7:130,632,368...130,659,353
Ensembl chr 7:130,633,348...130,659,168
JBrowse link
G Fmc1 formation of mitochondrial complex V assembly factor 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of FMC1 protein CTD PMID:32407736 NCBI chr 4:67,274,104...67,282,140
Ensembl chr 4:67,274,104...67,282,140
JBrowse link
G Gaa alpha glucosidase multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of GAA protein CTD PMID:32407736 NCBI chr10:104,529,673...104,546,836
Ensembl chr10:104,529,747...104,546,836
JBrowse link
G Gna14 G protein subunit alpha 14 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of GNA14 protein CTD PMID:32407736 NCBI chr 1:213,714,993...213,900,083
Ensembl chr 1:213,716,020...213,897,423
JBrowse link
G Gnai3 G protein subunit alpha i3 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of GNAI3 protein CTD PMID:32407736 NCBI chr 2:195,742,765...195,780,720
Ensembl chr 2:195,742,642...195,780,742
JBrowse link
G Gnb1 G protein subunit beta 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of GNB1 protein CTD PMID:32407736 NCBI chr 5:166,075,508...166,142,223
Ensembl chr 5:166,075,629...166,142,124
JBrowse link
G Golga1 golgin A1 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of GOLGA1 protein CTD PMID:32407736 NCBI chr 3:22,765,690...22,812,637
Ensembl chr 3:22,767,761...22,812,585
JBrowse link
G Gpnmb glycoprotein nmb multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of GPNMB protein CTD PMID:32407736 NCBI chr 4:78,010,247...78,031,491
Ensembl chr 4:78,010,197...78,049,367
JBrowse link
G Gpr18 G protein-coupled receptor 18 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of GPR18 mRNA CTD PMID:31100301 NCBI chr15:98,997,427...99,001,177
Ensembl chr15:98,997,259...99,001,470
JBrowse link
G Hexb hexosaminidase subunit beta multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of HEXB protein CTD PMID:32407736 NCBI chr 2:28,483,997...28,504,165
Ensembl chr 2:28,484,012...28,504,223
JBrowse link
G Hist2h2be histone cluster 2 H2B family member E multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of HIST2H2BE protein CTD PMID:32407736 NCBI chr 2:183,780,449...183,783,030 JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of HMGCS1 mRNA CTD PMID:31100301 NCBI chr 2:51,649,368...51,667,100
Ensembl chr 2:51,649,497...51,667,100
JBrowse link
G Hnrnpm heterogeneous nuclear ribonucleoprotein M multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of HNRNPM protein CTD PMID:32407736 NCBI chr 7:14,438,703...14,476,781
Ensembl chr 7:14,438,688...14,476,762
JBrowse link
G Hnrnpu heterogeneous nuclear ribonucleoprotein U multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of HNRNPU protein CTD PMID:32407736 NCBI chr13:90,069,058...90,086,905
Ensembl chr13:90,074,181...90,086,588
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of HSPA5 mRNA CTD PMID:31100301 NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
JBrowse link
G Immt inner membrane mitochondrial protein multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of IMMT protein CTD PMID:32407736 NCBI chr 4:103,880,482...103,919,116
Ensembl chr 4:103,880,459...103,919,109
JBrowse link
G Insig1 insulin induced gene 1 increases expression ISO beauvericin results in increased expression of INSIG1 mRNA CTD PMID:29203277 NCBI chr 4:7,315,494...7,323,972
Ensembl chr 4:7,315,495...7,323,952
JBrowse link
G Islr2 immunoglobulin superfamily containing leucine-rich repeat 2 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of ISLR2 protein CTD PMID:32407736 NCBI chr 8:58,608,165...58,616,246
Ensembl chr 8:58,608,709...58,614,650
JBrowse link
G Itgb1 integrin subunit beta 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of ITGB1 protein CTD PMID:32407736 NCBI chr19:56,705,123...56,753,199
Ensembl chr19:56,705,171...56,753,195
JBrowse link
G Klf12 Kruppel-like factor 12 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of KLF12 protein CTD PMID:32407736 NCBI chr15:76,628,778...77,062,000
Ensembl chr15:76,637,654...77,062,056
JBrowse link
G Kpnb1 karyopherin subunit beta 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of KPNB1 protein CTD PMID:32407736 NCBI chr10:82,145,662...82,174,437
Ensembl chr10:82,145,420...82,174,605
JBrowse link
G Krt16 keratin 16 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of KRT16 protein CTD PMID:32407736 NCBI chr10:85,168,357...85,171,744
Ensembl chr10:85,066,802...85,171,799
JBrowse link
G Krt27 keratin 27 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of KRT27 protein CTD PMID:32407736 NCBI chr10:84,298,684...84,303,967
Ensembl chr10:84,298,508...84,303,967
JBrowse link
G Krt5 keratin 5 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of KRT5 protein CTD PMID:32407736 NCBI chr 7:132,846,355...132,851,986
Ensembl chr 7:132,846,136...132,851,850
JBrowse link
G Krt76 keratin 76 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of KRT76 protein CTD PMID:32407736 NCBI chr 7:133,016,990...133,025,414
Ensembl chr 7:133,016,992...133,025,496
JBrowse link
G Lamp2 lysosomal-associated membrane protein 2 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of LAMP2 protein CTD PMID:32407736 NCBI chr  X:117,173,097...117,222,090
Ensembl chr  X:117,057,606...117,260,522
JBrowse link
G Lat linker for activation of T cells decreases expression ISO beauvericin results in decreased expression of LAT mRNA CTD PMID:29203277 NCBI chr 1:180,936,536...180,941,561
Ensembl chr 1:180,936,534...180,941,578
JBrowse link
G Mapk1 mitogen activated protein kinase 1 decreases phosphorylation EXP beauvericin results in decreased phosphorylation of MAPK1 protein CTD PMID:25178661 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 decreases phosphorylation EXP beauvericin results in decreased phosphorylation of MAPK3 protein CTD PMID:25178661 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Matn4 matrilin 4 decreases expression ISO beauvericin results in decreased expression of MATN4 mRNA CTD PMID:29203277 NCBI chr 3:153,120,605...153,135,628
Ensembl chr 3:153,120,632...153,135,865
JBrowse link
G Mavs mitochondrial antiviral signaling protein increases expression ISO beauvericin results in increased expression of MAVS mRNA CTD PMID:29203277 NCBI chr 3:118,451,650...118,466,094
Ensembl chr 3:118,451,743...118,466,094
JBrowse link
G Med6 mediator complex subunit 6 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of MED6 protein CTD PMID:32407736 NCBI chr 6:101,270,410...101,283,929
Ensembl chr 6:101,270,410...101,283,876
JBrowse link
G Moap1 modulator of apoptosis 1 increases expression ISO beauvericin results in increased expression of MOAP1 mRNA CTD PMID:29203277 NCBI chr 6:121,882,565...121,884,500
Ensembl chr 6:121,882,366...121,898,643
JBrowse link
G Mrpl12 mitochondrial ribosomal protein L12 decreases expression
multiple interactions
ISO beauvericin results in decreased expression of MRPL12 mRNA
[beauvericin co-treated with enniatins] results in decreased expression of MRPL12 mRNA
CTD PMID:29203277 PMID:31100301 NCBI chr10:105,758,410...105,762,913
Ensembl chr10:105,758,410...105,762,913
JBrowse link
G Mrpl4 mitochondrial ribosomal protein L4 decreases expression ISO beauvericin results in decreased expression of MRPL4 mRNA CTD PMID:29203277 NCBI chr 8:19,539,593...19,545,608
Ensembl chr 8:19,539,593...19,545,608
JBrowse link
G Mt-atp6 mitochondrially encoded ATP synthase membrane subunit 6 decreases expression
multiple interactions
ISO beauvericin results in decreased expression of ATP6 mRNA
[beauvericin co-treated with enniatins co-treated with ochratoxin A] results in increased expression of ATP6 mRNA; [beauvericin co-treated with enniatins] results in decreased expression of ATP6 mRNA; [beauvericin co-treated with enniatins] results in increased expression of ATP6 mRNA; [Plant Extracts co-treated with beauvericin co-treated with enniatins] results in decreased expression of ATP6 mRNA; [Plant Extracts co-treated with beauvericin] results in decreased expression of ATP6 mRNA; [Plant Extracts co-treated with ochratoxin A co-treated with Zearalenone co-treated with beauvericin] results in decreased expression of ATP6 mRNA
CTD PMID:29203277 PMID:31100301 PMID:34015425 NCBI chr MT:7,919...8,599
Ensembl chr MT:7,919...8,599
JBrowse link
G Mt-atp8 mitochondrially encoded ATP synthase membrane subunit 8 decreases expression
multiple interactions
ISO beauvericin results in decreased expression of ATP8 mRNA
[beauvericin co-treated with enniatins co-treated with ochratoxin A] results in decreased expression of ATP8 mRNA; [beauvericin co-treated with enniatins] affects the expression of ATP8 mRNA; [beauvericin co-treated with enniatins] results in decreased expression of ATP8 mRNA; [Plant Extracts co-treated with beauvericin co-treated with enniatins] results in decreased expression of ATP8 mRNA; [Plant Extracts co-treated with beauvericin] results in decreased expression of ATP8 mRNA; [Plant Extracts co-treated with ochratoxin A co-treated with Zearalenone co-treated with beauvericin] results in decreased expression of ATP8 mRNA
CTD PMID:29203277 PMID:31100301 PMID:34015425 NCBI chr MT:7,758...7,961
Ensembl chr MT:7,758...7,961
JBrowse link
G Mt-co1 mitochondrially encoded cytochrome c oxidase I multiple interactions
decreases expression
ISO [beauvericin co-treated with enniatins co-treated with ochratoxin A] results in decreased expression of COX1 mRNA; [beauvericin co-treated with enniatins] affects the expression of COX1 mRNA; [beauvericin co-treated with enniatins] results in decreased expression of COX1 mRNA; [Plant Extracts co-treated with beauvericin co-treated with enniatins] results in decreased expression of COX1 mRNA; [Plant Extracts co-treated with beauvericin] results in decreased expression of COX1 mRNA; [Plant Extracts co-treated with ochratoxin A co-treated with Zearalenone co-treated with beauvericin] results in decreased expression of COX1 mRNA
beauvericin results in decreased expression of COX1 mRNA
CTD PMID:31100301 PMID:34015425 NCBI chr MT:5,323...6,867
Ensembl chr MT:5,323...6,867
JBrowse link
G Mt-co3 mitochondrially encoded cytochrome c oxidase III decreases expression
multiple interactions
ISO beauvericin results in decreased expression of COX3 mRNA
[beauvericin co-treated with enniatins co-treated with ochratoxin A] results in decreased expression of COX3 mRNA; [beauvericin co-treated with enniatins] results in decreased expression of COX3 mRNA; [Plant Extracts co-treated with beauvericin co-treated with enniatins] results in decreased expression of COX3 mRNA; [Plant Extracts co-treated with beauvericin] results in decreased expression of COX3 mRNA; [Plant Extracts co-treated with ochratoxin A co-treated with Zearalenone co-treated with beauvericin] results in decreased expression of COX3 mRNA
CTD PMID:29203277 PMID:31100301 PMID:34015425 NCBI chr MT:8,599...9,382
Ensembl chr MT:8,599...9,382
JBrowse link
G Mt-cyb mitochondrially encoded cytochrome b decreases expression ISO beauvericin results in decreased expression of CYTB mRNA CTD PMID:29203277 NCBI chr MT:14,136...15,278
Ensembl chr MT:14,136...15,278
JBrowse link
G Mt-nd2 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 2 decreases expression
increases expression
multiple interactions
ISO beauvericin results in decreased expression of ND2 mRNA
beauvericin results in increased expression of ND2 mRNA
[beauvericin co-treated with enniatins co-treated with ochratoxin A] results in increased expression of ND2 mRNA; [beauvericin co-treated with enniatins] results in decreased expression of ND2 mRNA; [beauvericin co-treated with enniatins] results in increased expression of ND2 mRNA; [Plant Extracts co-treated with beauvericin co-treated with enniatins] results in increased expression of ND2 mRNA; [Plant Extracts co-treated with beauvericin] results in increased expression of ND2 mRNA; [Plant Extracts co-treated with ochratoxin A co-treated with Zearalenone co-treated with beauvericin] results in increased expression of ND2 mRNA
CTD PMID:29203277 PMID:31100301 PMID:34015425 NCBI chr MT:3,904...4,942
Ensembl chr MT:3,904...4,942
JBrowse link
G Mt-nd3 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 3 decreases expression
increases expression
multiple interactions
ISO beauvericin results in decreased expression of ND3 mRNA
beauvericin results in increased expression of ND3 mRNA
[beauvericin co-treated with enniatins co-treated with ochratoxin A] results in increased expression of ND3 mRNA; [beauvericin co-treated with enniatins] results in decreased expression of ND3 mRNA; [beauvericin co-treated with enniatins] results in increased expression of ND3 mRNA; [Plant Extracts co-treated with beauvericin co-treated with enniatins] results in increased expression of ND3 mRNA; [Plant Extracts co-treated with beauvericin] results in increased expression of ND3 mRNA; [Plant Extracts co-treated with ochratoxin A co-treated with Zearalenone co-treated with beauvericin] results in increased expression of ND3 mRNA
CTD PMID:29203277 PMID:31100301 PMID:34015425 NCBI chr MT:9,451...9,798
Ensembl chr MT:9,451...9,798
JBrowse link
G Mt-nd4 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 4 decreases expression
multiple interactions
ISO beauvericin results in decreased expression of ND4 mRNA
[beauvericin co-treated with enniatins co-treated with ochratoxin A] results in decreased expression of ND4 mRNA; [beauvericin co-treated with enniatins] results in decreased expression of ND4 mRNA; [beauvericin co-treated with enniatins] results in increased expression of ND4 mRNA; [Plant Extracts co-treated with beauvericin co-treated with enniatins] results in increased expression of ND4 mRNA; [Plant Extracts co-treated with beauvericin] results in increased expression of ND4 mRNA; [Plant Extracts co-treated with ochratoxin A co-treated with Zearalenone co-treated with beauvericin] results in decreased expression of ND4 mRNA
CTD PMID:29203277 PMID:31100301 PMID:34015425 NCBI chr MT:10,160...11,537
Ensembl chr MT:10,160...11,537
JBrowse link
G Mt-nd4l mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 4L decreases expression
increases expression
multiple interactions
ISO beauvericin results in decreased expression of ND4L mRNA
beauvericin results in increased expression of ND4L mRNA
[beauvericin co-treated with enniatins co-treated with ochratoxin A] results in increased expression of ND4L mRNA; [beauvericin co-treated with enniatins] results in decreased expression of ND4L mRNA; [Plant Extracts co-treated with beauvericin co-treated with enniatins] results in increased expression of ND4L mRNA; [Plant Extracts co-treated with beauvericin] results in increased expression of ND4L mRNA
CTD PMID:29203277 PMID:31100301 PMID:34015425 NCBI chr MT:9,870...10,166
Ensembl chr MT:9,870...10,166
JBrowse link
G Mt-nd5 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 5 decreases expression
increases expression
multiple interactions
ISO beauvericin results in decreased expression of ND5 mRNA
beauvericin results in increased expression of ND5 mRNA
[beauvericin co-treated with enniatins co-treated with ochratoxin A] results in increased expression of ND5 mRNA; [beauvericin co-treated with enniatins] results in decreased expression of ND5 mRNA; [Plant Extracts co-treated with beauvericin co-treated with enniatins] results in increased expression of ND5 mRNA; [Plant Extracts co-treated with beauvericin] results in increased expression of ND5 mRNA
CTD PMID:29203277 PMID:31100301 PMID:34015425 NCBI chr MT:11,736...13,565
Ensembl chr MT:11,736...13,565
JBrowse link
G Mt-nd6 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 6 decreases expression
multiple interactions
ISO beauvericin results in decreased expression of ND6 mRNA
[beauvericin co-treated with enniatins co-treated with ochratoxin A] results in decreased expression of ND6 mRNA; [beauvericin co-treated with enniatins] results in decreased expression of ND6 mRNA; [Plant Extracts co-treated with beauvericin co-treated with enniatins] results in increased expression of ND6 mRNA; [Plant Extracts co-treated with beauvericin] results in increased expression of ND6 mRNA
CTD PMID:34015425 NCBI chr MT:13,543...14,061
Ensembl chr MT:13,543...14,061
JBrowse link
G Mtrf1l mitochondrial translation release factor 1 like multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of MTRF1L protein CTD PMID:32407736 NCBI chr 1:42,208,553...42,221,020
Ensembl chr 1:42,210,583...42,220,836
JBrowse link
G Myo18a myosin XVIIIa increases expression ISO beauvericin results in increased expression of TIAF1 mRNA CTD PMID:29203277 NCBI chr10:62,654,218...62,755,464
Ensembl chr10:62,654,281...62,755,468
JBrowse link
G Nars1 asparaginyl-tRNA synthetase 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of NARS1 protein CTD PMID:32407736 NCBI chr18:57,989,308...58,005,639
Ensembl chr18:57,989,308...58,005,622
JBrowse link
G Nars2 asparaginyl-tRNA synthetase 2, mitochondrial multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of NARS2 protein CTD PMID:32407736 NCBI chr 1:151,300,446...151,412,069
Ensembl chr 1:151,300,467...151,413,521
JBrowse link
G Ndrg1 N-myc downstream regulated 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of NDRG1 protein CTD PMID:32407736 NCBI chr 7:98,684,487...98,725,869
Ensembl chr 7:98,684,487...98,725,880
JBrowse link
G Nlrp1a NLR family, pyrin domain containing 1A increases expression ISO beauvericin results in increased expression of NLRP1 mRNA CTD PMID:29203277 NCBI chr10:55,778,560...55,833,639
Ensembl chr10:55,778,560...55,825,180
JBrowse link
G Nod1 nucleotide-binding oligomerization domain containing 1 increases expression ISO beauvericin results in increased expression of NOD1 mRNA CTD PMID:29203277 NCBI chr 4:84,060,871...84,111,668
Ensembl chr 4:84,060,880...84,111,404
JBrowse link
G Nol3 nucleolar protein 3 increases expression ISO beauvericin results in increased expression of NOL3 mRNA CTD PMID:29203277 NCBI chr19:33,154,061...33,158,250
Ensembl chr19:33,154,062...33,158,250
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of NQO1 mRNA CTD PMID:31100301 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Nudt1 nudix hydrolase 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of NUDT1 protein CTD PMID:32407736 NCBI chr12:14,302,514...14,309,559
Ensembl chr12:14,302,694...14,305,826
JBrowse link
G Oga O-GlcNAcase increases expression ISO beauvericin results in increased expression of OGA mRNA CTD PMID:29203277 NCBI chr 1:244,598,285...244,633,835
Ensembl chr 1:244,598,292...244,634,359
JBrowse link
G Ogt O-linked N-acetylglucosamine (GlcNAc) transferase increases expression ISO beauvericin results in increased expression of OGT mRNA CTD PMID:29203277 NCBI chr  X:66,771,278...66,816,148
Ensembl chr  X:66,771,349...66,816,146
JBrowse link
G Osgin1 oxidative stress induced growth inhibitor 1 multiple interactions
increases expression
ISO [beauvericin co-treated with enniatins co-treated with ochratoxin A] results in decreased expression of OSGIN1 mRNA; [beauvericin co-treated with enniatins] results in decreased expression of OSGIN1 mRNA; [Plant Extracts co-treated with beauvericin] results in increased expression of OSGIN1 mRNA
beauvericin results in increased expression of OSGIN1 mRNA
CTD PMID:31100301 PMID:34015425 NCBI chr19:47,471,750...47,500,517
Ensembl chr19:47,492,171...47,500,516
JBrowse link
G Ostc oligosaccharyltransferase complex non-catalytic subunit multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of OSTC protein CTD PMID:32407736 NCBI chr 2:219,250,549...219,266,076
Ensembl chr 2:219,236,952...219,266,107
JBrowse link
G Parvg parvin, gamma multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of PARVG protein CTD PMID:32407736 NCBI chr 7:115,456,183...115,475,707
Ensembl chr 7:115,456,209...115,475,104
JBrowse link
G Pawr pro-apoptotic WT1 regulator decreases expression ISO beauvericin results in decreased expression of PAWR mRNA CTD PMID:29203277 NCBI chr 7:43,645,028...43,725,033
Ensembl chr 7:43,645,084...43,725,028
JBrowse link
G Pdcd11 programmed cell death 11 decreases expression ISO beauvericin results in decreased expression of PDCD11 mRNA CTD PMID:29203277 NCBI chr 1:245,980,840...246,021,999
Ensembl chr 1:245,980,880...246,021,999
JBrowse link
G Pdcd2 programmed cell death 2 decreases expression ISO beauvericin results in decreased expression of PDCD2 mRNA CTD PMID:29203277 NCBI chr 1:56,484,947...56,490,437
Ensembl chr 1:56,463,931...56,490,437
JBrowse link
G Pdcd2l programmed cell death 2-like increases expression ISO beauvericin results in increased expression of PDCD2L mRNA CTD PMID:29203277 NCBI chr 1:86,810,292...86,822,554
Ensembl chr 1:86,810,292...86,822,554
JBrowse link
G Pdcd4 programmed cell death 4 decreases expression ISO beauvericin results in decreased expression of PDCD4 mRNA CTD PMID:29203277 NCBI chr 1:252,921,342...252,944,278
Ensembl chr 1:252,921,392...252,944,275
JBrowse link
G Pdcd5 programmed cell death 5 increases expression ISO beauvericin results in increased expression of PDCD5 mRNA CTD PMID:29203277 NCBI chr 1:88,305,869...88,311,200
Ensembl chr 1:88,305,869...88,311,200
JBrowse link
G Pdcd6ip programmed cell death 6 interacting protein increases expression ISO beauvericin results in increased expression of PDCD6IP mRNA CTD PMID:29203277 NCBI chr 8:113,590,998...113,646,795
Ensembl chr 8:113,590,998...113,646,773
JBrowse link
G Pdia4 protein disulfide isomerase family A, member 4 decreases expression ISO beauvericin results in decreased expression of PDIA4 mRNA CTD PMID:29203277 NCBI chr 4:76,803,198...76,822,245
Ensembl chr 4:76,803,198...76,822,107
JBrowse link
G Pfn1 profilin 1 decreases expression
multiple interactions
ISO beauvericin results in decreased expression of PFN1 mRNA
[beauvericin co-treated with enniatins] results in increased expression of PFN1 protein
CTD PMID:29203277 PMID:32407736 NCBI chr10:55,365,263...55,367,968
Ensembl chr10:55,365,262...55,527,631
JBrowse link
G Pgam1 phosphoglycerate mutase 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of PGAM1 protein CTD PMID:32407736 NCBI chr 1:240,723,832...240,731,443
Ensembl chr 1:240,723,920...240,738,452
JBrowse link
G Pgk1 phosphoglycerate kinase 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of PGK1 protein CTD PMID:32407736 NCBI chr  X:71,271,454...71,287,429
Ensembl chr  X:71,271,440...71,287,418
JBrowse link
G Phgdh phosphoglycerate dehydrogenase multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of PHGDH protein CTD PMID:32407736 NCBI chr 2:185,906,964...185,936,160
Ensembl chr 2:185,906,966...185,935,944
JBrowse link
G Phka2 phosphorylase kinase regulatory subunit alpha 2 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of PHKA2 protein CTD PMID:32407736 NCBI chr  X:34,170,959...34,293,498
Ensembl chr  X:34,171,323...34,293,466
JBrowse link
G Pidd1 p53-induced death domain protein 1 decreases expression ISO beauvericin results in decreased expression of PIDD1 mRNA CTD PMID:29203277 NCBI chr 1:196,536,815...196,542,808
Ensembl chr 1:196,536,834...196,542,699
JBrowse link
G Plk1 polo-like kinase 1 decreases expression ISO beauvericin results in decreased expression of PLK1 mRNA CTD PMID:29203277 NCBI chr 1:176,716,420...176,726,400
Ensembl chr 1:176,716,420...176,726,400
JBrowse link
G Pls3 plastin 3 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of PLS3 protein CTD PMID:32407736 NCBI chr  X:111,589,193...111,683,908
Ensembl chr  X:111,589,254...111,683,891
JBrowse link
G Ppa1 inorganic pyrophosphatase 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of PPA1 protein CTD PMID:32407736 NCBI chr20:29,590,733...29,617,711
Ensembl chr20:29,590,707...29,619,215
JBrowse link
G Ppan peter pan homolog decreases expression ISO beauvericin results in decreased expression of PPAN mRNA CTD PMID:29203277 NCBI chr 8:19,423,908...19,427,941
Ensembl chr 8:19,423,961...19,427,938
JBrowse link
G Ppib peptidylprolyl isomerase B decreases expression ISO beauvericin results in decreased expression of PPIB mRNA CTD PMID:29203277 NCBI chr 8:66,603,877...66,609,734
Ensembl chr 8:66,603,861...66,630,428
JBrowse link
G Ppp1r14b protein phosphatase 1, regulatory (inhibitor) subunit 14B decreases expression ISO beauvericin results in decreased expression of PPP1R14B mRNA CTD PMID:29203277 NCBI chr 1:204,165,210...204,167,320
Ensembl chr 1:204,163,299...204,167,319
JBrowse link
G Ppt1 palmitoyl-protein thioesterase 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of PPT1 protein CTD PMID:32407736 NCBI chr 5:135,121,176...135,141,076
Ensembl chr 5:135,121,163...135,142,048
JBrowse link
G Prkca protein kinase C, alpha multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of PRKCA protein CTD PMID:32407736 NCBI chr10:92,889,390...93,288,013
Ensembl chr10:92,894,012...93,288,012
JBrowse link
G Psma5 proteasome 20S subunit alpha 5 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of PSMA5 protein CTD PMID:32407736 NCBI chr 2:195,896,369...195,919,733
Ensembl chr 2:195,896,365...195,919,731
JBrowse link
G Psme4 proteasome activator subunit 4 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of PSME4 protein CTD PMID:32407736 NCBI chr14:104,505,716...104,609,410
Ensembl chr14:104,505,716...104,609,408
JBrowse link
G Ptges3 prostaglandin E synthase 3 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of PTGES3 protein CTD PMID:32407736 NCBI chr 7:490,698...507,759
Ensembl chr 7:490,656...508,084
JBrowse link
G Ptprc protein tyrosine phosphatase, receptor type, C multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of PTPRC protein CTD PMID:32407736 NCBI chr13:49,596,193...49,708,283
Ensembl chr13:49,596,193...49,708,692
JBrowse link
G Rab11fip5 RAB11 family interacting protein 5 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of RAB11FIP5 protein CTD PMID:32407736 NCBI chr 4:117,871,301...117,908,819
Ensembl chr 4:117,871,308...117,908,741
JBrowse link
G Rab5a RAB5A, member RAS oncogene family multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of RAB5A protein CTD PMID:32407736 NCBI chr 9:6,483,906...6,512,877
Ensembl chr 9:6,484,469...6,512,873
JBrowse link
G Rac3 Rac family small GTPase 3 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of RAC3 protein CTD PMID:32407736 NCBI chr10:106,002,808...106,005,244
Ensembl chr10:105,993,087...106,005,260
JBrowse link
G Rap1a RAP1A, member of RAS oncogene family multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of RAP1A protein CTD PMID:32407736 NCBI chr 2:193,208,631...193,286,513
Ensembl chr 2:193,208,635...193,286,501
JBrowse link
G Relt RELT, TNF receptor decreases expression ISO beauvericin results in decreased expression of RELT mRNA CTD PMID:29203277 NCBI chr 1:155,206,976...155,224,609
Ensembl chr 1:155,206,976...155,214,196
JBrowse link
G Rp2 RP2 activator of ARL3 GTPase multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of RP2 protein CTD PMID:32407736 NCBI chr  X:1,872,581...1,916,704
Ensembl chr  X:1,873,306...1,916,688
JBrowse link
G Rpl37a ribosomal protein L37a multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of RPL37A protein CTD PMID:32407736
G Rpl5 ribosomal protein L5 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of RPL5 protein CTD PMID:32407736 NCBI chr14:1,843,856...1,850,301
Ensembl chr14:1,843,770...1,850,290
JBrowse link
G Rpl8 ribosomal protein L8 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of RPL8 protein CTD PMID:32407736 NCBI chr 7:108,626,194...108,628,485
Ensembl chr 7:108,622,324...108,628,482
JBrowse link
G Rxra retinoid X receptor alpha multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of RXRA protein CTD PMID:32407736 NCBI chr 3:10,989,832...11,076,366
Ensembl chr 3:10,989,832...11,073,712
JBrowse link
G Scml2 Scm polycomb group protein like 2 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of SCML2 protein CTD PMID:32407736 NCBI chr  X:33,523,179...33,677,672
Ensembl chr  X:33,524,530...33,652,742
JBrowse link
G Sdf2l1 stromal cell-derived factor 2-like 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of SDF2L1 protein CTD PMID:32407736 NCBI chr11:83,872,659...83,874,902
Ensembl chr11:83,872,659...83,874,902
JBrowse link
G Sdr42e2 short chain dehydrogenase/reductase family 42E, member 2 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of SDR42E2 protein CTD PMID:32407736 NCBI chr 1:175,361,630...175,382,769
Ensembl chr 1:175,362,150...175,382,050
JBrowse link
G Sec13 SEC13 homolog, nuclear pore and COPII coat complex component decreases expression ISO beauvericin results in decreased expression of SEC13 mRNA CTD PMID:29203277 NCBI chr 4:146,877,739...146,891,130
Ensembl chr 4:146,875,524...146,891,173
JBrowse link
G Siva1 SIVA1, apoptosis-inducing factor decreases expression ISO beauvericin results in decreased expression of SIVA1 mRNA CTD PMID:29203277 NCBI chr 6:131,705,312...131,709,697
Ensembl chr 6:131,705,323...131,709,690
JBrowse link
G Slc1a5 solute carrier family 1 member 5 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of SLC1A5 protein CTD PMID:32407736 NCBI chr 1:77,456,849...77,470,952
Ensembl chr 1:77,456,694...77,470,952
JBrowse link
G Slc2a1 solute carrier family 2 member 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of SLC2A1 protein CTD PMID:32407736 NCBI chr 5:132,717,196...132,745,416
Ensembl chr 5:132,717,196...132,745,416
JBrowse link
G Slc3a2 solute carrier family 3 member 2 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of SLC3A2 protein CTD PMID:32407736 NCBI chr 1:205,604,468...205,618,931
Ensembl chr 1:205,604,468...205,618,931
JBrowse link
G Snrpd2 small nuclear ribonucleoprotein D2 polypeptide multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of SNRPD2 protein CTD PMID:32407736 NCBI chr 1:78,798,377...78,801,227
Ensembl chr 1:78,798,377...78,803,351
JBrowse link
G Snrpd3 small nuclear ribonucleoprotein D3 polypeptide multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of SNRPD3 protein CTD PMID:32407736 NCBI chr20:13,130,112...13,145,947
Ensembl chr20:13,130,119...13,145,978
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase decreases activity EXP beauvericin results in decreased activity of SRC protein CTD PMID:25178661 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476
JBrowse link
G Srm spermidine synthase decreases expression ISO beauvericin results in decreased expression of SRM mRNA CTD PMID:29203277 NCBI chr 5:159,025,919...159,029,076
Ensembl chr 5:159,025,873...159,029,405
JBrowse link
G Srsf7 serine and arginine rich splicing factor 7 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of SRSF7 protein CTD PMID:32407736 NCBI chr 6:14,811,775...14,818,968
Ensembl chr 6:14,811,808...14,818,965
JBrowse link
G Srxn1 sulfiredoxin 1 multiple interactions
decreases expression
ISO [beauvericin co-treated with enniatins co-treated with ochratoxin A] results in decreased expression of SRXN1 mRNA; [beauvericin co-treated with enniatins] results in decreased expression of SRXN1 mRNA; [Plant Extracts co-treated with beauvericin co-treated with enniatins] results in decreased expression of SRXN1 mRNA; [Plant Extracts co-treated with beauvericin] results in decreased expression of SRXN1 mRNA
beauvericin results in decreased expression of SRXN1 mRNA
CTD PMID:31100301 PMID:34015425 NCBI chr 3:140,604,490...140,610,050
Ensembl chr 3:140,599,608...140,628,448
JBrowse link
G Ssbp1 single stranded DNA binding protein 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of SSBP1 protein CTD PMID:32407736 NCBI chr 4:69,266,024...69,276,135
Ensembl chr 4:69,266,102...69,276,135
JBrowse link
G Tbc1d2b TBC1 domain family, member 2B multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of TBC1D2B protein CTD PMID:32407736 NCBI chr 8:90,746,220...90,814,867
Ensembl chr 8:90,746,233...90,814,832
JBrowse link
G Tcn2 transcobalamin 2 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of TCN2 protein CTD PMID:32407736 NCBI chr14:78,813,343...78,828,549
Ensembl chr14:78,813,343...78,828,489
JBrowse link
G Tcp11l1 t-complex 11 like 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of TCP11L1 protein CTD PMID:32407736 NCBI chr 3:91,047,006...91,092,687
Ensembl chr 3:90,998,270...91,092,006
JBrowse link
G Tcp11l2 t-complex 11 like 2 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of TCP11L2 protein CTD PMID:32407736 NCBI chr 7:19,150,241...19,185,135
Ensembl chr 7:19,150,252...19,185,095
JBrowse link
G Thyn1 thymocyte nuclear protein 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of THYN1 protein CTD PMID:32407736 NCBI chr 8:25,406,563...25,415,444
Ensembl chr 8:25,406,500...25,415,445
JBrowse link
G Timm9 translocase of inner mitochondrial membrane 9 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of TIMM9 protein CTD PMID:32407736 NCBI chr 6:89,610,094...89,622,924
Ensembl chr 6:89,610,094...89,622,924
JBrowse link
G Tk1 thymidine kinase 1 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of TK1 protein CTD PMID:32407736 NCBI chr10:103,034,755...103,046,125
Ensembl chr10:103,031,521...103,046,920
JBrowse link
G Tmem263 transmembrane protein 263 multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of TMEM263 protein CTD PMID:32407736 NCBI chr 7:18,607,077...18,628,436
Ensembl chr 7:18,610,149...18,628,534
JBrowse link
G Tnfsf10 TNF superfamily member 10 decreases expression ISO beauvericin results in decreased expression of TNFSF10 mRNA CTD PMID:29203277 NCBI chr 2:110,199,835...110,227,239
Ensembl chr 2:110,207,916...110,225,135
JBrowse link
G Tomm22 translocase of outer mitochondrial membrane 22 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of TOMM22 protein CTD PMID:32407736 NCBI chr 7:111,223,508...111,228,671
Ensembl chr 7:111,216,571...111,246,799
JBrowse link
G Tomm7 translocase of outer mitochondrial membrane 7 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of TOMM7 protein CTD PMID:32407736 NCBI chr 4:11,305,122...11,311,963
Ensembl chr 4:11,305,110...11,311,962
JBrowse link
G Tuba1b tubulin, alpha 1B multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of TUBA1B protein CTD PMID:32407736 NCBI chr 7:130,090,669...130,093,644
Ensembl chr 7:130,081,032...130,196,186
JBrowse link
G Tubb3 tubulin, beta 3 class III multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of TUBB3 protein CTD PMID:32407736 NCBI chr19:51,457,187...51,466,243
Ensembl chr19:51,457,184...51,466,243
JBrowse link
G Tubb4a tubulin, beta 4A class IVa multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of TUBB4A protein CTD PMID:32407736 NCBI chr 9:1,917,841...1,925,286
Ensembl chr 9:1,917,845...1,925,291
JBrowse link
G Tubb4b tubulin, beta 4B class IVb multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of TUBB4B protein CTD PMID:32407736 NCBI chr 3:8,037,844...8,040,294
Ensembl chr 3:8,037,799...8,040,296
JBrowse link
G Tubb5 tubulin, beta 5 class I multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of TUBB protein CTD PMID:32407736 NCBI chr20:2,912,779...2,916,928
Ensembl chr20:2,912,778...2,916,940
JBrowse link
G Txnip thioredoxin interacting protein increases expression
multiple interactions
decreases expression
ISO beauvericin results in increased expression of TXNIP mRNA
[beauvericin co-treated with enniatins co-treated with ochratoxin A] results in increased expression of TXNIP mRNA; [Plant Extracts co-treated with beauvericin co-treated with enniatins] results in increased expression of TXNIP mRNA; [Plant Extracts co-treated with beauvericin] results in increased expression of TXNIP mRNA
beauvericin results in decreased expression of TXNIP mRNA
CTD PMID:29203277 PMID:34015425 NCBI chr 2:184,093,079...184,096,882
Ensembl chr 2:184,092,991...184,096,886
JBrowse link
G Ucp2 uncoupling protein 2 multiple interactions
decreases expression
ISO [beauvericin co-treated with enniatins co-treated with ochratoxin A] results in increased expression of UCP2 mRNA; [beauvericin co-treated with enniatins] results in decreased expression of UCP2 mRNA; [Plant Extracts co-treated with beauvericin co-treated with enniatins] results in increased expression of UCP2 mRNA; [Plant Extracts co-treated with beauvericin] results in increased expression of UCP2 mRNA; [Plant Extracts co-treated with ochratoxin A co-treated with Zearalenone co-treated with beauvericin] results in decreased expression of UCP2 mRNA
beauvericin results in decreased expression of UCP2 mRNA
CTD PMID:31100301 PMID:34015425 NCBI chr 1:154,839,242...154,845,612
Ensembl chr 1:154,839,209...154,845,611
JBrowse link
G Ucp3 uncoupling protein 3 multiple interactions ISO [beauvericin co-treated with enniatins] results in decreased expression of UCP3 mRNA CTD PMID:31100301 NCBI chr 1:154,815,777...154,828,764
Ensembl chr 1:154,815,777...154,828,762
JBrowse link
G Ybx1 Y box binding protein 1 decreases expression ISO beauvericin results in decreased expression of YBX1 mRNA CTD PMID:29203277 NCBI chr 5:132,882,137...132,899,108
Ensembl chr 5:132,882,145...132,898,862
JBrowse link
G Ybx3 Y box binding protein 3 decreases expression ISO beauvericin results in decreased expression of YBX3 mRNA CTD PMID:29203277 NCBI chr 4:165,129,747...165,153,101
Ensembl chr 4:165,129,758...165,153,161
JBrowse link
G Ykt6 YKT6 v-SNARE homolog multiple interactions ISO [beauvericin co-treated with enniatins] results in increased expression of YKT6 protein CTD PMID:32407736 NCBI chr14:80,832,187...80,843,394
Ensembl chr14:80,832,187...80,843,385
JBrowse link
carbonyl cyanide p-trifluoromethoxyphenylhydrazone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agt angiotensinogen multiple interactions EXP [Egtazic Acid co-treated with Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone] inhibits the reaction [AGT protein results in increased abundance of Reactive Oxygen Species] CTD PMID:18854758 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977
JBrowse link
G Akt1 AKT serine/threonine kinase 1 increases phosphorylation ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in increased phosphorylation of AKT1 protein CTD PMID:19901985 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Aqp9 aquaporin 9 multiple interactions ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone inhibits the reaction [AQP9 protein results in increased uptake of Lactic Acid]; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone inhibits the reaction [AQP9 protein results in increased uptake of Selenious Acid] CTD PMID:28798983 NCBI chr 8:71,797,231...71,837,485
Ensembl chr 8:71,797,234...71,837,395
JBrowse link
G Bax BCL2 associated X, apoptosis regulator decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of BAX mRNA CTD PMID:16039398 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2l1 Bcl2-like 1 decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of BCL2L1 mRNA CTD PMID:16039398 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
JBrowse link
G Casp3 caspase 3 increases activity ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in increased activity of CASP3 protein CTD PMID:20683024 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp8 caspase 8 decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of CASP8 mRNA CTD PMID:16039398 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Cat catalase decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of CAT mRNA CTD PMID:16039398 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Ccnc cyclin C decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of CCNC mRNA CTD PMID:16039398 NCBI chr 5:35,266,828...35,284,943
Ensembl chr 5:35,266,823...35,296,584
JBrowse link
G Ccnd1 cyclin D1 decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of CCND1 mRNA CTD PMID:16039398 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Ccng1 cyclin G1 decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of CCNG1 mRNA CTD PMID:16039398 NCBI chr10:25,176,231...25,182,604
Ensembl chr10:25,176,234...25,181,641
JBrowse link
G Cdk4 cyclin-dependent kinase 4 multiple interactions ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone promotes the reaction [CDKN1B protein binds to CDK4 protein] CTD PMID:19819288 NCBI chr 7:62,885,647...62,889,562
Ensembl chr 7:62,883,105...62,942,403
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B multiple interactions
increases expression
ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone promotes the reaction [CDKN1B protein binds to CDK4 protein]
Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in increased expression of CDKN1B protein
CTD PMID:19819288 NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982
JBrowse link
G Comt catechol-O-methyltransferase decreases activity
multiple interactions
ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased activity of COMT protein
[Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased activity of COMT protein] which results in decreased abundance of Adenosine Triphosphate
CTD PMID:14975680 NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642
JBrowse link
G Coq10a coenzyme Q10A decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of COQ10A protein CTD PMID:21308897 NCBI chr 7:792,089...798,392
Ensembl chr 7:792,089...800,161
JBrowse link
G Coq2 coenzyme Q2, polyprenyltransferase increases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in increased expression of COQ2 mRNA CTD PMID:21308897 NCBI chr14:8,941,429...8,961,418
Ensembl chr14:8,941,461...8,960,891
JBrowse link
G Coq3 coenzyme Q3 methyltransferase decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of COQ3 mRNA CTD PMID:21308897 NCBI chr 5:35,429,567...35,460,613
Ensembl chr 5:35,429,574...35,460,607
JBrowse link
G Coq4 coenzyme Q4 increases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in increased expression of COQ4 mRNA CTD PMID:21308897 NCBI chr 3:13,060,054...13,070,502
Ensembl chr 3:13,060,455...13,068,799
JBrowse link
G Coq5 coenzyme Q5, methyltransferase increases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in increased expression of COQ5 mRNA CTD PMID:21308897 NCBI chr12:41,316,922...41,333,855
Ensembl chr12:41,316,748...41,333,848
JBrowse link
G Coq6 coenzyme Q6 monooxygenase increases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in increased expression of COQ6 mRNA CTD PMID:21308897 NCBI chr 6:104,007,814...104,019,888
Ensembl chr 6:104,007,872...104,024,657
JBrowse link
G Coq7 coenzyme Q7, hydroxylase increases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in increased expression of COQ7 mRNA CTD PMID:21308897 NCBI chr 1:172,836,359...172,851,173
Ensembl chr 1:172,835,188...172,851,158
JBrowse link
G Coq8a coenzyme Q8A increases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in increased expression of COQ8A mRNA CTD PMID:21308897 NCBI chr13:91,904,731...91,933,588
Ensembl chr13:91,904,739...91,931,431
JBrowse link
G Coq9 coenzyme Q9 increases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in increased expression of COQ9 mRNA CTD PMID:21308897 NCBI chr19:10,166,948...10,179,976
Ensembl chr19:10,166,951...10,179,949
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in increased expression of CYP1A1 mRNA CTD PMID:16039398 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Ddb1 damage-specific DNA binding protein 1 decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of DDB1 mRNA CTD PMID:16039398 NCBI chr 1:207,252,890...207,278,685
Ensembl chr 1:207,252,890...207,278,676
JBrowse link
G Dnaja1 DnaJ heat shock protein family (Hsp40) member A1 decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of DNAJA1 mRNA CTD PMID:16039398 NCBI chr 5:55,842,414...55,853,326
Ensembl chr 5:55,842,426...55,853,967
JBrowse link
G Egr1 early growth response 1 decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of EGR1 mRNA CTD PMID:16039398 NCBI chr18:26,463,333...26,465,531
Ensembl chr18:26,462,981...26,466,766
JBrowse link
G Ephx2 epoxide hydrolase 2 decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of EPHX2 mRNA CTD PMID:16039398 NCBI chr15:40,289,901...40,327,632
Ensembl chr15:40,289,902...40,327,615
JBrowse link
G Fmr1 FMRP translational regulator 1 multiple interactions ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone inhibits the reaction [FMR1 5' UTR mutant form results in increased abundance of Hydroxyl Radical]; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone inhibits the reaction [FMR1 5' UTR mutant form results in increased abundance of Superoxides] CTD PMID:27385396 NCBI chr  X:147,240,239...147,278,057
Ensembl chr  X:147,240,301...147,278,050
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of GADD45A mRNA CTD PMID:16039398 NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115
JBrowse link
G Gdf15 growth differentiation factor 15 increases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in increased expression of GDF15 mRNA CTD PMID:16039398 NCBI chr16:18,805,312...18,807,893
Ensembl chr16:18,805,239...18,808,055
JBrowse link
G Gsr glutathione-disulfide reductase decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of GSR mRNA CTD PMID:16039398 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
JBrowse link
G Gstm5 glutathione S-transferase, mu 5 decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of GSTM3 mRNA CTD PMID:16039398 NCBI chr 2:195,531,627...195,534,562
Ensembl chr 2:195,531,495...195,534,553
JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in increased expression of HMOX1 mRNA CTD PMID:16039398 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hmox2 heme oxygenase 2 decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of HMOX2 mRNA CTD PMID:16039398 NCBI chr10:10,797,076...10,831,178
Ensembl chr10:10,797,055...10,831,148
JBrowse link
G Hsf1 heat shock transcription factor 1 decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of HSF1 mRNA CTD PMID:16039398 NCBI chr 7:108,196,040...108,223,011
Ensembl chr 7:108,196,056...108,223,011
JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of HSP90AA1 mRNA CTD PMID:16039398 NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of HSPA1A mRNA CTD PMID:16039398
G Hspa1b heat shock protein family A (Hsp70) member 1B decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of HSPA1B mRNA CTD PMID:16039398 NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240
JBrowse link
G Hspa1l heat shock protein family A (Hsp70) member 1 like decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of HSPA1L mRNA CTD PMID:16039398 NCBI chr20:3,848,843...3,855,571
Ensembl chr20:3,848,843...3,855,571
JBrowse link
G Hspa2 heat shock protein family A (Hsp70) member 2 decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of HSPA2 mRNA CTD PMID:16039398 NCBI chr 6:95,128,504...95,131,281
Ensembl chr 6:95,128,350...95,131,287
JBrowse link
G Hspa4 heat shock protein family A (Hsp70) member 4 decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of HSPA4 mRNA CTD PMID:16039398 NCBI chr10:37,408,025...37,449,080
Ensembl chr10:37,408,025...37,449,001
JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of HSPA8 mRNA CTD PMID:16039398 NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259
JBrowse link
G Hspe1 heat shock protein family E (Hsp10) member 1 increases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in increased expression of HSPE1 mRNA CTD PMID:16039398 NCBI chr 9:56,589,912...56,593,000
Ensembl chr 9:56,589,789...56,593,089
JBrowse link
G Icam1 intercellular adhesion molecule 1 decreases expression EXP Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of ICAM1 mRNA CTD PMID:17416599 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Il18 interleukin 18 decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of IL18 mRNA CTD PMID:16039398 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887
JBrowse link
G Il1a interleukin 1 alpha decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of IL1A mRNA CTD PMID:16039398 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
JBrowse link
G Kcnj12 potassium inwardly-rectifying channel, subfamily J, member 12 multiple interactions ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone inhibits the reaction [KCNJ12 protein results in increased transport of Potassium] CTD PMID:12118013 NCBI chr10:45,696,621...45,745,528
Ensembl chr10:45,696,849...45,745,492
JBrowse link
G Kcnj4 potassium inwardly-rectifying channel, subfamily J, member 4 multiple interactions ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone inhibits the reaction [KCNJ4 protein results in increased transport of Potassium] CTD PMID:12118013 NCBI chr 7:111,047,097...111,074,151
Ensembl chr 7:111,047,094...111,074,151
JBrowse link
G Mdm2 MDM2 proto-oncogene decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of MDM2 mRNA CTD PMID:16039398 NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915
JBrowse link
G Mt1 metallothionein 1 decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of MT1A mRNA CTD PMID:16039398 NCBI chr19:10,826,032...10,827,048
Ensembl chr19:10,826,032...10,827,049
JBrowse link
G Mt2A metallothionein 2A decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of MT2A mRNA CTD PMID:16039398 NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784
JBrowse link
G Nfkbia NFKB inhibitor alpha decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of NFKBIA mRNA CTD PMID:16039398 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Nipa1 NIPA magnesium transporter 1 decreases expression EXP Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of NIPA1 mRNA CTD PMID:27157538 NCBI chr 1:106,834,000...106,875,148
Ensembl chr 1:106,834,000...106,874,790
JBrowse link
G Pdss1 decaprenyl diphosphate synthase subunit 1 decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of PDSS1 mRNA CTD PMID:21308897 NCBI chr17:85,059,953...85,098,739
Ensembl chr17:85,060,106...85,098,730
JBrowse link
G Pdss2 decaprenyl diphosphate synthase subunit 2 increases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in increased expression of PDSS2 mRNA CTD PMID:21308897 NCBI chr20:46,709,631...46,938,704
Ensembl chr20:46,709,649...46,938,708
JBrowse link
G Pink1 PTEN induced kinase 1 multiple interactions ISO PINK1 protein affects the reaction [Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone affects the localization of PRKN protein] CTD PMID:24879156 NCBI chr 5:150,530,523...150,542,635
Ensembl chr 5:150,530,523...150,542,635
JBrowse link
G Plcg1 phospholipase C, gamma 1 increases phosphorylation ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in increased phosphorylation of PLCG1 protein CTD PMID:19901985 NCBI chr 3:149,385,587...149,416,330
Ensembl chr 3:149,385,587...149,416,330
JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A multiple interactions ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone promotes the reaction [TARDBP protein binds to PPP1R15A protein] CTD PMID:29109149 NCBI chr 1:96,000,053...96,003,128
Ensembl chr 1:96,000,058...96,003,171
JBrowse link
G Prkaa1 protein kinase AMP-activated catalytic subunit alpha 1 increases phosphorylation ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in increased phosphorylation of PRKAA1 protein CTD PMID:19901985 NCBI chr 2:54,240,298...54,275,978
Ensembl chr 2:54,240,137...54,275,978
JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase multiple interactions
affects localization
ISO PINK1 protein affects the reaction [Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone affects the localization of PRKN protein] CTD PMID:24879156 NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in increased expression of PTGS2 mRNA CTD PMID:16039398 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Rad23a RAD23 homolog A, nucleotide excision repair protein decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of RAD23A mRNA CTD PMID:16039398 NCBI chr19:23,313,563...23,320,702
Ensembl chr19:23,314,797...23,320,695
JBrowse link
G Rpl13a ribosomal protein L13A decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of RPL13A mRNA CTD PMID:16039398 NCBI chr 1:95,609,374...95,612,557
Ensembl chr 1:95,609,370...95,620,463
JBrowse link
G Serpine1 serpin family E member 1 decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of SERPINE1 mRNA CTD PMID:16039398 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
JBrowse link
G Slc18a2 solute carrier family 18 member A2 multiple interactions EXP Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone inhibits the reaction [SLC18A2 protein results in increased uptake of Serotonin] CTD PMID:1438304 NCBI chr 1:258,413,748...258,449,143
Ensembl chr 1:258,413,959...258,448,325
JBrowse link
G Slc41a2 solute carrier family 41 member 2 increases expression EXP Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in increased expression of SLC41A2 mRNA CTD PMID:27157538 NCBI chr 7:20,383,714...20,491,178
Ensembl chr 7:20,383,757...20,491,166
JBrowse link
G Sod2 superoxide dismutase 2 increases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in increased expression of SOD2 mRNA CTD PMID:16039398 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
JBrowse link
G Stat3 signal transducer and activator of transcription 3 affects response to substance ISO STAT3 protein affects the susceptibility to Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone CTD PMID:20224768 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
JBrowse link
G Tardbp TAR DNA binding protein multiple interactions ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone promotes the reaction [TARDBP protein binds to PPP1R15A protein] CTD PMID:29109149 NCBI chr 5:159,050,518...159,062,218
Ensembl chr 5:159,051,799...159,062,055
JBrowse link
G Xrcc5 X-ray repair cross complementing 5 decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of XRCC5 mRNA CTD PMID:16039398 NCBI chr 9:73,955,220...74,044,020
Ensembl chr 9:73,955,216...74,044,018
JBrowse link
CCCP term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agt angiotensinogen multiple interactions EXP Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [Glucose results in increased expression of AGT mRNA]; Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [Glucose results in increased expression of AGT protein] CTD PMID:12130563 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977
JBrowse link
G Ambra1 autophagy and beclin 1 regulator 1 multiple interactions ISO Carbonyl Cyanide m-Chlorophenyl Hydrazone promotes the reaction [AMBRA1 protein binds to PRKN protein] CTD PMID:24879156 NCBI chr 3:77,700,936...77,890,221
Ensembl chr 3:77,700,936...77,890,221
JBrowse link
G Atm ATM serine/threonine kinase multiple interactions
increases phosphorylation
ISO ATM protein affects the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone results in decreased expression of COX4 protein]; Carbonyl Cyanide m-Chlorophenyl Hydrazone promotes the reaction [PINK1 protein binds to ATM protein]
Carbonyl Cyanide m-Chlorophenyl Hydrazone results in increased phosphorylation of ATM protein
CTD PMID:29660402 NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437
JBrowse link
G Becn1 beclin 1 multiple interactions ISO
EXP
Carbonyl Cyanide m-Chlorophenyl Hydrazone promotes the reaction [BECN1 protein binds to PRKN protein]
BECN1 protein inhibits the reaction [BECN1 protein affects the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone affects the localization of PRKN protein]]; Carbonyl Cyanide m-Chlorophenyl Hydrazone promotes the reaction [BECN1 protein binds to PRKN protein]
BECN1 protein affects the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone affects the localization of PINK1 protein]; BECN1 protein affects the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone affects the localization of PRKN protein]; BECN1 protein affects the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone results in decreased expression of and results in increased ubiquitination of MFN2 protein]; BECN1 protein affects the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone results in increased phosphorylation of PRKN protein]; Carbonyl Cyanide m-Chlorophenyl Hydrazone promotes the reaction [BECN1 protein binds to PRKN protein]
CTD PMID:24879156 NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742
JBrowse link
G Bnip3l BCL2 interacting protein 3 like increases phosphorylation
multiple interactions
ISO Carbonyl Cyanide m-Chlorophenyl Hydrazone results in increased phosphorylation of BNIP3L protein
BNIP3L protein affects the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone results in decreased expression of COX4 protein]; BNIP3L protein affects the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone results in decreased expression of HSPD1 protein]
CTD PMID:32142837 NCBI chr15:41,174,594...41,197,730
Ensembl chr15:41,174,594...41,197,803
JBrowse link
G Canx calnexin affects localization ISO Carbonyl Cyanide m-Chlorophenyl Hydrazone affects the localization of CANX protein CTD PMID:28940366 NCBI chr10:34,623,865...34,656,866
Ensembl chr10:34,625,191...34,656,821
JBrowse link
G Casp1 caspase 1 multiple interactions ISO Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide, E coli O55-B5] results in increased cleavage of CASP1 protein] CTD PMID:33524445 NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383
JBrowse link
G Casp3 caspase 3 multiple interactions
increases expression
EXP
ISO
Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [Testosterone results in increased cleavage of CASP3 protein]
DNM1L protein promotes the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone results in increased expression of CASP3 protein modified form]; PGAM5 protein promotes the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone results in increased expression of CASP3 protein modified form]
CTD PMID:24658017 PMID:29241732 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp9 caspase 9 increases expression
multiple interactions
ISO Carbonyl Cyanide m-Chlorophenyl Hydrazone results in increased expression of CASP9 protein modified form
DNM1L protein promotes the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone results in increased expression of CASP9 protein modified form]
CTD PMID:29241732 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Cirbp cold inducible RNA binding protein decreases expression ISO Carbonyl Cyanide m-Chlorophenyl Hydrazone results in decreased expression of CIRBP mRNA CTD PMID:15075239 NCBI chr 7:9,533,857...9,538,899
Ensembl chr 7:9,424,178...9,538,818
JBrowse link
G Cox4i1 cytochrome c oxidase subunit 4i1 decreases expression ISO Carbonyl Cyanide m-Chlorophenyl Hydrazone results in decreased expression of COX4I1 protein CTD PMID:27318970 NCBI chr19:48,721,680...48,727,920
Ensembl chr19:48,721,199...48,727,921
JBrowse link
G Ctsl cathepsin L increases expression ISO Carbonyl Cyanide m-Chlorophenyl Hydrazone results in increased expression of CTSL mRNA CTD PMID:15978749 NCBI chr17:764,370...770,533
Ensembl chr17:764,309...770,548
JBrowse link
G Dnm1l dynamin 1-like multiple interactions
decreases expression
ISO DNM1L protein promotes the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone results in increased expression of CASP3 protein modified form]; DNM1L protein promotes the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone results in increased expression of CASP9 protein modified form]
Carbonyl Cyanide m-Chlorophenyl Hydrazone results in decreased expression of DNM1L protein modified form
CTD PMID:28940366 PMID:29241732 NCBI chr11:84,581,216...84,632,382
Ensembl chr11:84,581,216...84,631,482
JBrowse link
G Faslg Fas ligand multiple interactions EXP Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [Testosterone results in increased expression of FASLG mRNA] CTD PMID:24658017 NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215
JBrowse link
G Fkbp5 FKBP prolyl isomerase 5 multiple interactions ISO [Carbonyl Cyanide m-Chlorophenyl Hydrazone results in increased expression of and affects the localization of PINK1 protein] promotes the reaction [FKBP5 protein binds to PINK1 protein] CTD PMID:30734931 NCBI chr20:6,457,207...6,575,404
Ensembl chr20:6,457,216...6,541,674
JBrowse link
G Fmc1 formation of mitochondrial complex V assembly factor 1 decreases expression
multiple interactions
ISO Carbonyl Cyanide m-Chlorophenyl Hydrazone results in decreased expression of FMC1 protein
bafilomycin A1 inhibits the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone results in decreased expression of FMC1 protein]
CTD PMID:29371327 NCBI chr 4:67,274,104...67,282,140
Ensembl chr 4:67,274,104...67,282,140
JBrowse link
G Hk2 hexokinase 2 multiple interactions ISO Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of HK2 protein] CTD PMID:34481905 NCBI chr 4:115,234,509...115,283,530
Ensembl chr 4:115,234,509...115,283,530
JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 decreases expression
multiple interactions
ISO Carbonyl Cyanide m-Chlorophenyl Hydrazone results in decreased expression of HSPD1 protein
BNIP3L protein affects the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone results in decreased expression of HSPD1 protein]
CTD PMID:32142837 NCBI chr 9:56,579,195...56,590,011
Ensembl chr 9:56,579,201...56,589,662
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of IL1B mRNA] CTD PMID:33524445 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 multiple interactions ISO [[Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [SQSTM1 protein binds to KEAP1 protein]] promotes the reaction [KEAP1 protein binds to NFE2L2 protein]] which results in decreased activity of NFE2L2 protein; [Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [SQSTM1 protein binds to KEAP1 protein]] promotes the reaction [KEAP1 protein binds to NFE2L2 protein]; Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [SQSTM1 protein binds to KEAP1 protein] CTD PMID:30715550 NCBI chr 8:19,768,375...19,777,862
Ensembl chr 8:19,768,375...19,777,862
JBrowse link
G Ldha lactate dehydrogenase A multiple interactions ISO Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of LDHA protein] CTD PMID:34481905 NCBI chr 1:97,371,823...97,381,247
Ensembl chr 1:97,366,021...97,433,472
JBrowse link
G Lep leptin multiple interactions
decreases response to substance
ISO Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [LEP protein results in increased chemical synthesis of Reactive Oxygen Species]
Carbonyl Cyanide m-Chlorophenyl Hydrazone results in decreased susceptibility to LEP protein
CTD PMID:11342529 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
JBrowse link
G Lonp1 lon peptidase 1, mitochondrial increases expression ISO Carbonyl Cyanide m-Chlorophenyl Hydrazone results in increased expression of LONP1 mRNA CTD PMID:28940366 NCBI chr 9:1,447,444...1,459,771
Ensembl chr 9:1,447,447...1,459,771
JBrowse link
G Mapt microtubule-associated protein tau affects localization EXP Carbonyl Cyanide m-Chlorophenyl Hydrazone affects the localization of MAPT protein CTD PMID:17634376 NCBI chr10:89,138,644...89,236,137
Ensembl chr10:89,138,627...89,236,129
JBrowse link
G Mfn2 mitofusin 2 multiple interactions EXP
ISO
BECN1 protein affects the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone results in decreased expression of and results in increased ubiquitination of MFN2 protein]; Carbonyl Cyanide m-Chlorophenyl Hydrazone results in decreased expression of and results in increased ubiquitination of MFN2 protein
Carbonyl Cyanide m-Chlorophenyl Hydrazone results in decreased expression of and affects the localization of MFN2 protein
CTD PMID:24879156 PMID:28940366 NCBI chr 5:158,304,285...158,335,502
Ensembl chr 5:158,304,287...158,335,342
JBrowse link
G Mt-nd1 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 1 decreases expression
multiple interactions
ISO Carbonyl Cyanide m-Chlorophenyl Hydrazone results in decreased expression of ND1 protein
Deoxyglucose inhibits the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone results in decreased expression of ND1 protein]
CTD PMID:34481905 NCBI chr MT:2,740...3,694
Ensembl chr MT:2,740...3,694
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions ISO [[Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [SQSTM1 protein binds to KEAP1 protein]] promotes the reaction [KEAP1 protein binds to NFE2L2 protein]] which results in decreased activity of NFE2L2 protein; [Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [SQSTM1 protein binds to KEAP1 protein]] promotes the reaction [KEAP1 protein binds to NFE2L2 protein] CTD PMID:30715550 NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 increases expression ISO Carbonyl Cyanide m-Chlorophenyl Hydrazone results in increased expression of NFKB1 protein CTD PMID:15978749 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
JBrowse link
G Nfkbib NFKB inhibitor beta decreases expression ISO Carbonyl Cyanide m-Chlorophenyl Hydrazone results in decreased expression of NFKBIB protein CTD PMID:15978749 NCBI chr 1:84,046,292...84,053,862
Ensembl chr 1:84,046,295...84,053,862
JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 multiple interactions ISO Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of NLRP3 protein] CTD PMID:33524445 NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811
JBrowse link
G Opa1 OPA1, mitochondrial dynamin like GTPase decreases expression ISO Carbonyl Cyanide m-Chlorophenyl Hydrazone results in decreased expression of OPA1 protein alternative form CTD PMID:28940366 NCBI chr11:71,108,100...71,185,170
Ensembl chr11:71,109,873...71,185,109
JBrowse link
G Park7 Parkinsonism associated deglycase multiple interactions ISO PARK7 gene mutant form promotes the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone affects the localization of PRKN protein] CTD PMID:22872702 NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970
JBrowse link
G Pgam5 PGAM family member 5, mitochondrial serine/threonine protein phosphatase multiple interactions ISO PGAM5 protein promotes the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone results in increased expression of CASP3 protein modified form] CTD PMID:29241732 NCBI chr12:46,409,324...46,416,410
Ensembl chr12:46,409,369...46,416,420
JBrowse link
G Pik3c3 phosphatidylinositol 3-kinase, catalytic subunit type 3 multiple interactions ISO Carbonyl Cyanide m-Chlorophenyl Hydrazone promotes the reaction [PIK3C3 protein binds to PRKN protein] CTD PMID:24879156 NCBI chr18:21,845,282...21,934,387
Ensembl chr18:21,845,295...21,929,048
JBrowse link
G Pink1 PTEN induced kinase 1 multiple interactions
affects localization
increases expression
increases stability
ISO
EXP
PINK1 gene mutant form inhibits the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone affects the localization of PRKN protein]
BECN1 protein affects the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone affects the localization of PINK1 protein]; PINK1 protein affects the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone affects the localization of PRKN protein]
[Carbonyl Cyanide m-Chlorophenyl Hydrazone co-treated with PRKN protein] results in increased expression of PINK1 protein; [Carbonyl Cyanide m-Chlorophenyl Hydrazone results in increased expression of and affects the localization of PINK1 protein] promotes the reaction [FKBP5 protein binds to PINK1 protein]; Carbonyl Cyanide m-Chlorophenyl Hydrazone promotes the reaction [PINK1 protein binds to ATM protein]; Carbonyl Cyanide m-Chlorophenyl Hydrazone results in increased expression of and affects the localization of PINK1 protein; Carbonyl Cyanide m-Chlorophenyl Hydrazone results in increased expression of and results in increased phosphorylation of PINK1 protein
Carbonyl Cyanide m-Chlorophenyl Hydrazone results in increased expression of PINK1 protein
Carbonyl Cyanide m-Chlorophenyl Hydrazone results in increased stability of PINK1 protein
CTD PMID:22872702 PMID:24879156 PMID:26070385 PMID:27318970 PMID:28673964 More... NCBI chr 5:150,530,523...150,542,635
Ensembl chr 5:150,530,523...150,542,635
JBrowse link
G Pkm pyruvate kinase M1/2 multiple interactions ISO Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of PKM protein] CTD PMID:34481905 NCBI chr 8:60,057,629...60,079,600
Ensembl chr 8:60,057,402...60,079,599
JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase affects localization
increases response to substance
decreases response to substance
affects expression
decreases expression
increases phosphorylation
multiple interactions
ISO
EXP
Carbonyl Cyanide m-Chlorophenyl Hydrazone affects the localization of PRKN protein
PRKN gene mutant form results in increased susceptibility to Carbonyl Cyanide m-Chlorophenyl Hydrazone
PRKN protein results in decreased susceptibility to Carbonyl Cyanide m-Chlorophenyl Hydrazone
Carbonyl Cyanide m-Chlorophenyl Hydrazone affects the expression of PRKN protein alternative form
Carbonyl Cyanide m-Chlorophenyl Hydrazone results in decreased expression of PRKN protein
Carbonyl Cyanide m-Chlorophenyl Hydrazone results in increased phosphorylation of PRKN protein
1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt inhibits the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone affects the localization of PRKN protein]; Acetylcysteine inhibits the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone affects the localization of PRKN protein]; Carbonyl Cyanide m-Chlorophenyl Hydrazone promotes the reaction [BECN1 protein binds to PRKN protein]; PARK7 gene mutant form promotes the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone affects the localization of PRKN protein]; PINK1 gene mutant form inhibits the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone affects the localization of PRKN protein]
BECN1 protein affects the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone affects the localization of PRKN protein]; BECN1 protein affects the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone results in increased phosphorylation of PRKN protein]; Carbonyl Cyanide m-Chlorophenyl Hydrazone promotes the reaction [BECN1 protein binds to PRKN protein]; PINK1 protein affects the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone affects the localization of PRKN protein]
[Carbonyl Cyanide m-Chlorophenyl Hydrazone co-treated with PRKN protein] results in increased expression of PINK1 protein; BECN1 protein inhibits the reaction [BECN1 protein affects the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone affects the localization of PRKN protein]]; Carbonyl Cyanide m-Chlorophenyl Hydrazone promotes the reaction [AMBRA1 protein binds to PRKN protein]; Carbonyl Cyanide m-Chlorophenyl Hydrazone promotes the reaction [BECN1 protein binds to PRKN protein]; Carbonyl Cyanide m-Chlorophenyl Hydrazone promotes the reaction [PIK3C3 protein binds to PRKN protein]; Tretinoin affects the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone affects the expression of PRKN protein alternative form]
CTD PMID:16517603 PMID:22872702 PMID:24879156 PMID:26070385 PMID:28673964 More... NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [Sodium Chloride results in increased expression of PTGS2 protein]
Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [Glucose results in increased expression of PTGS2 mRNA]; Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [Glucose results in increased expression of PTGS2 protein]
CTD PMID:14514642 PMID:16024921 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Rbm3 RNA binding motif protein 3 decreases expression ISO Carbonyl Cyanide m-Chlorophenyl Hydrazone results in decreased expression of RBM3 mRNA CTD PMID:15075239 NCBI chr  X:14,348,909...14,352,387
Ensembl chr  X:14,348,910...14,353,580
JBrowse link
G Rel REL proto-oncogene, NF-kB subunit increases expression ISO Carbonyl Cyanide m-Chlorophenyl Hydrazone results in increased expression of REL protein CTD PMID:15978749 NCBI chr14:97,690,105...97,721,194
Ensembl chr14:97,695,161...97,720,892
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO [Carbonyl Cyanide m-Chlorophenyl Hydrazone co-treated with Adenosine Triphosphate co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of RELA protein; Carbonyl Cyanide m-Chlorophenyl Hydrazone affects the reaction [lipopolysaccharide, E coli O55-B5 affects the localization of RELA protein]; Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide, E coli O55-B5] results in increased phosphorylation of RELA protein] CTD PMID:33524445 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Slc2a1 solute carrier family 2 member 1 multiple interactions ISO Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of SLC2A1 protein] CTD PMID:34481905 NCBI chr 5:132,717,196...132,745,416
Ensembl chr 5:132,717,196...132,745,416
JBrowse link
G Sqstm1 sequestosome 1 multiple interactions ISO [[Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [SQSTM1 protein binds to KEAP1 protein]] promotes the reaction [KEAP1 protein binds to NFE2L2 protein]] which results in decreased activity of NFE2L2 protein; [Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [SQSTM1 protein binds to KEAP1 protein]] promotes the reaction [KEAP1 protein binds to NFE2L2 protein]; Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of SQSTM1 protein]; Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [SQSTM1 protein binds to KEAP1 protein] CTD PMID:30715550 PMID:34481905 NCBI chr10:34,525,517...34,536,685
Ensembl chr10:34,525,519...34,536,673
JBrowse link
G Timm23 translocase of inner mitochondrial membrane 23 decreases expression ISO Carbonyl Cyanide m-Chlorophenyl Hydrazone results in decreased expression of TIMM23 protein CTD PMID:29371327 NCBI chr16:7,410,308...7,436,392
Ensembl chr16:7,409,688...7,436,379
JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP
ISO
Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [Testosterone results in increased expression of TNF mRNA]
Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of TNF mRNA]
CTD PMID:24658017 PMID:33524445 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
chlortetracycline term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cat catalase decreases activity ISO Chlortetracycline results in decreased activity of CAT protein CTD PMID:30768968 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Gstp1 glutathione S-transferase pi 1 multiple interactions ISO Chlortetracycline inhibits the reaction [GSTP1 protein results in increased metabolism of 1-chloro-2,4-dinitrobenzene-glutathione conjugate] CTD PMID:23769903 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
JBrowse link
desferrioxamine B term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aco1 aconitase 1 increases activity
increases expression
multiple interactions
EXP
ISO
Deferoxamine results in increased activity of ACO1 protein
Deferoxamine results in increased expression of ACO1 protein
[Deferoxamine results in decreased abundance of Iron] which results in increased activity of ACO1 protein
CTD PMID:10397746 PMID:11054110 PMID:15893546 PMID:16568477 PMID:18073202 More... NCBI chr 5:55,259,841...55,315,872
Ensembl chr 5:55,259,827...55,316,391
JBrowse link
G Aco2 aconitase 2 decreases expression EXP Deferoxamine results in decreased expression of ACO2 protein CTD PMID:16568477 PMID:17469137 NCBI chr 7:113,385,677...113,428,794
Ensembl chr 7:113,385,646...113,428,261
JBrowse link
G Acp5 acid phosphatase 5, tartrate resistant decreases activity
multiple interactions
ISO Deferoxamine results in decreased activity of ACP5 protein
Deferoxamine inhibits the reaction [TF protein results in increased activity of ACP5 protein]; TF protein inhibits the reaction [Deferoxamine results in decreased activity of ACP5 protein]
CTD PMID:31238089 NCBI chr 8:20,663,984...20,670,604
Ensembl chr 8:20,663,985...20,667,929
JBrowse link
G Acta2 actin alpha 2, smooth muscle decreases expression
increases expression
multiple interactions
EXP
ISO
Deferoxamine results in decreased expression of ACTA2 protein
Deferoxamine results in increased expression of ACTA2 mRNA
Deferoxamine inhibits the reaction [Artesunate results in decreased expression of ACTA2 mRNA]
CTD PMID:18032466 PMID:30551460 NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554
JBrowse link
G Adm adrenomedullin increases expression ISO Deferoxamine results in increased expression of ADM mRNA CTD PMID:11754965 NCBI chr 1:164,745,484...164,747,655
Ensembl chr 1:164,745,466...164,747,654
JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions EXP Deferoxamine inhibits the reaction [PDGFB protein results in increased phosphorylation of AKT1 protein] CTD PMID:18032466 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Aldh3a1 aldehyde dehydrogenase 3 family, member A1 decreases expression
multiple interactions
ISO Deferoxamine results in decreased expression of ALDH3A1 mRNA
Deferoxamine inhibits the reaction [Benzo(a)pyrene results in increased expression of ALDH3A1 mRNA]
CTD PMID:14645679 NCBI chr10:45,892,993...45,902,680
Ensembl chr10:45,892,924...45,902,681
JBrowse link
G Alpl alkaline phosphatase, biomineralization associated decreases expression
multiple interactions
ISO Deferoxamine results in decreased expression of ALPL mRNA
Indomethacin promotes the reaction [Deferoxamine results in decreased expression of ALPL protein]; Sulindac promotes the reaction [Deferoxamine results in decreased expression of ALPL protein]
CTD PMID:16772336 PMID:21882223 NCBI chr 5:149,951,397...150,006,424
Ensembl chr 5:149,951,409...150,006,446
JBrowse link
G Anxa3 annexin A3 multiple interactions
decreases expression
ISO ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of ANXA3 protein]
Deferoxamine results in decreased expression of ANXA3 protein
CTD PMID:19515424 NCBI chr14:12,727,708...12,781,717
Ensembl chr14:12,719,795...12,781,617
JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 multiple interactions ISO [Glucose co-treated with Deferoxamine] results in increased expression of APAF1 mRNA; Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of APAF1 mRNA] CTD PMID:33962019 NCBI chr 7:25,494,143...25,579,540
Ensembl chr 7:25,494,609...25,579,540
JBrowse link
G App amyloid beta precursor protein affects binding
multiple interactions
ISO Deferoxamine binds to APP 5' UTR
[Deferoxamine binds to APP 5' UTR] which results in decreased expression of APP protein; [Deferoxamine binds to APP 5' UTR] which results in decreased secretion of APP protein modified form; Deferoxamine inhibits the reaction [[[[APP protein modified form binds to Copper] which co-treated with Ascorbic Acid] results in increased oxidation of phosphatidylcholine hydroperoxide] which results in increased chemical synthesis of 4-hydroxy-2-nonenal]
CTD PMID:15681799 PMID:17964426 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
JBrowse link
G Aqp4 aquaporin 4 multiple interactions EXP Deferoxamine inhibits the reaction [manganese(III) acetate dihydrate results in increased expression of AQP4 protein] CTD PMID:20648640 NCBI chr18:6,507,903...6,524,558
Ensembl chr18:6,507,903...6,524,856
JBrowse link
G Arhgdia Rho GDP dissociation inhibitor alpha decreases expression
multiple interactions
ISO Deferoxamine results in decreased expression of ARHGDIA protein
ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of ARHGDIA protein]
CTD PMID:19515424 NCBI chr10:105,854,526...105,858,020
Ensembl chr10:105,854,533...105,858,023
JBrowse link
G Arnt aryl hydrocarbon receptor nuclear translocator increases activity
multiple interactions
increases expression
EXP
ISO
Deferoxamine results in increased activity of ARNT protein
[Glucose co-treated with Deferoxamine] results in increased expression of ARNT mRNA; Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of ARNT mRNA]
Deferoxamine results in increased expression of ARNT mRNA
CTD PMID:10559391 PMID:33962019 NCBI chr 2:182,997,731...183,056,584
Ensembl chr 2:182,997,736...183,056,580
JBrowse link
G Ash2l ASH2 like histone lysine methyltransferase complex subunit increases expression
affects expression
ISO Deferoxamine results in increased expression of ASH2L mRNA
Deferoxamine affects the expression of ASH2L mRNA
CTD PMID:23483119 NCBI chr16:66,242,205...66,264,064
Ensembl chr16:66,242,212...66,264,061
JBrowse link
G Atf1 activating transcription factor 1 increases activity EXP Deferoxamine results in increased activity of ATF1 protein CTD PMID:10559391 NCBI chr 7:131,361,962...131,404,677
Ensembl chr 7:131,362,450...131,404,670
JBrowse link
G Atm ATM serine/threonine kinase multiple interactions ISO Deferoxamine results in increased phosphorylation of and results in increased activity of ATM protein CTD PMID:16959548 NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437
JBrowse link
G Atp6v0d2 ATPase H+ transporting V0 subunit D2 multiple interactions
affects expression
ISO Deferoxamine affects the reaction [TF protein affects the expression of ATP6V0D2 mRNA]; TF protein affects the reaction [Deferoxamine affects the expression of ATP6V0D2 mRNA] CTD PMID:31238089 NCBI chr 5:33,336,257...33,385,354
Ensembl chr 5:33,336,264...33,385,354
JBrowse link
G Atp7a ATPase copper transporting alpha increases expression
multiple interactions
EXP Deferoxamine results in increased expression of ATP7A mRNA
cupric chloride promotes the reaction [Deferoxamine results in increased expression of ATP7A mRNA]; Deferoxamine promotes the reaction [cupric chloride results in increased expression of ATP7A protein]
CTD PMID:23174565 NCBI chr  X:71,094,144...71,201,550
Ensembl chr  X:71,094,202...71,198,354
JBrowse link
G Bak1 BCL2-antagonist/killer 1 multiple interactions ISO [Glucose co-treated with Deferoxamine] results in increased expression of BAK1 mRNA; Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of BAK1 mRNA] CTD PMID:33962019 NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression
multiple interactions
ISO Deferoxamine results in increased expression of BAX mRNA; Deferoxamine results in increased expression of BAX protein
[Cisplatin co-treated with Deferoxamine] results in increased expression of BAX protein; [Glucose co-treated with Deferoxamine] results in increased expression of BAX mRNA; [Glucose co-treated with Deferoxamine] results in increased expression of BAX protein; Deferoxamine inhibits the reaction [Hydrogen Peroxide affects the localization of BAX protein]; Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of BAX mRNA]; Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of BAX protein]; TP53 protein affects the reaction [Deferoxamine results in increased expression of BAX protein]
CTD PMID:16800926 PMID:21742779 PMID:33962019 PMID:34126102 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bbc3 Bcl-2 binding component 3 increases expression
multiple interactions
ISO Deferoxamine results in increased expression of BBC3 mRNA
[Glucose co-treated with Deferoxamine] results in increased expression of BBC3 mRNA; Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of BBC3 mRNA]
CTD PMID:33962019 NCBI chr 1:77,013,281...77,022,509
Ensembl chr 1:77,014,543...77,022,509
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
decreases expression
EXP
ISO
Deferoxamine inhibits the reaction [Copper Sulfate results in decreased expression of BCL2 mRNA]
Deferoxamine results in decreased expression of BCL2 mRNA
[Glucose co-treated with Deferoxamine] results in decreased expression of BCL2 mRNA; [Glucose co-treated with Deferoxamine] results in decreased expression of BCL2 protein; Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in decreased expression of BCL2 mRNA]; Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in decreased expression of BCL2 protein]
CTD PMID:30431687 PMID:33962019 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Bcl2l15 BCL2-like 15 increases expression
multiple interactions
ISO Deferoxamine results in increased expression of BCL2L15 mRNA
[Glucose co-treated with Deferoxamine] results in increased expression of BCL2L15 mRNA; Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of BCL2L15 mRNA]
CTD PMID:33962019 NCBI chr 2:191,338,959...191,344,078
Ensembl chr 2:191,338,959...191,344,078
JBrowse link
G Becn1 beclin 1 multiple interactions ISO Deferoxamine inhibits the reaction [di-n-propyldithiocarbamate results in increased expression of BECN1 protein]; Deferoxamine inhibits the reaction [Hydrogen Peroxide affects the localization of BECN1 protein] CTD PMID:21742779 PMID:32687844 NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742
JBrowse link
G Bid BH3 interacting domain death agonist multiple interactions ISO [Glucose co-treated with Deferoxamine] results in increased expression of BID mRNA; Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of BID mRNA] CTD PMID:33962019 NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720
JBrowse link
G Bmp6 bone morphogenetic protein 6 multiple interactions
decreases expression
ISO Deferoxamine inhibits the reaction [BMP6 protein results in increased expression of HAMP mRNA]; ferric ammonium citrate affects the reaction [Deferoxamine inhibits the reaction [BMP6 protein results in increased expression of HAMP mRNA]]
Deferoxamine results in decreased expression of BMP6 mRNA
CTD PMID:25633564 PMID:32816093 NCBI chr17:26,318,121...26,469,034
Ensembl chr17:26,318,569...26,470,365
JBrowse link
G Bnip3 BCL2 interacting protein 3 increases expression
multiple interactions
ISO Deferoxamine results in increased expression of BNIP3 mRNA
[Glucose co-treated with Deferoxamine] results in increased expression of BNIP3 mRNA; Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of BNIP3 mRNA]
CTD PMID:33962019 NCBI chr 1:193,708,164...193,725,348
Ensembl chr 1:193,708,167...193,725,359
JBrowse link
G Bnip3l BCL2 interacting protein 3 like increases expression
multiple interactions
ISO Deferoxamine results in increased expression of BNIP3L mRNA
[Glucose co-treated with Deferoxamine] results in increased expression of BNIP3L mRNA; Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of BNIP3L mRNA]
CTD PMID:11832486 PMID:33962019 NCBI chr15:41,174,594...41,197,730
Ensembl chr15:41,174,594...41,197,803
JBrowse link
G C5 complement C5 multiple interactions ISO Deferoxamine inhibits the reaction [Asbestos, Crocidolite results in increased cleavage of C5 protein]; Deferoxamine inhibits the reaction [Asbestos, Serpentine results in increased cleavage of C5 protein] CTD PMID:10777245 NCBI chr 3:18,270,696...18,361,994
Ensembl chr 3:18,270,696...18,361,994
JBrowse link
G Ca9 carbonic anhydrase 9 increases expression ISO Deferoxamine results in increased expression of CA9 mRNA CTD PMID:25351418 NCBI chr 5:57,763,234...57,769,838
Ensembl chr 5:57,763,206...57,769,838
JBrowse link
G Cacna1h calcium voltage-gated channel subunit alpha1 H increases expression EXP Deferoxamine results in increased expression of CACNA1H mRNA CTD PMID:12679337 NCBI chr10:14,390,104...14,448,204
Ensembl chr10:14,390,113...14,448,376
JBrowse link
G Car2 carbonic anhydrase 2 decreases expression ISO Deferoxamine results in decreased expression of CAR2 mRNA CTD PMID:31238089 NCBI chr 2:86,741,625...86,756,766
Ensembl chr 2:86,741,626...86,756,818
JBrowse link
G Casp12 caspase 12 multiple interactions ISO Deferoxamine promotes the reaction [manganese chloride results in increased cleavage of and results in increased activity of CASP12 protein] CTD PMID:23764342 NCBI chr 8:2,642,296...2,669,549
Ensembl chr 8:2,642,434...2,674,037
JBrowse link
G Casp3 caspase 3 increases expression
multiple interactions
increases activity
ISO
EXP
Deferoxamine results in increased expression of CASP3 protein
Deferoxamine inhibits the reaction [ferric ammonium citrate results in increased cleavage of CASP3 protein]
Deferoxamine results in increased activity of CASP3 protein
[Glucose co-treated with Deferoxamine] results in increased expression of CASP3 mRNA; [Glucose co-treated with Deferoxamine] results in increased expression of CASP3 protein; [Glucose co-treated with Deferoxamine] results in increased expression of CASP3 protein modified form; Deferoxamine inhibits the reaction [Cisplatin results in increased cleavage of CASP3 protein]; Deferoxamine inhibits the reaction [Doxorubicin results in increased cleavage of CASP3 protein]; Deferoxamine promotes the reaction [manganese chloride results in increased activity of CASP3 protein]; Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of CASP3 mRNA]; Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of CASP3 protein modified form]; Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of CASP3 protein]; Nitroprusside inhibits the reaction [Deferoxamine results in increased activity of CASP3 protein]; Vanadates inhibits the reaction [Deferoxamine results in increased activity of CASP3 protein]
Deferoxamine inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased activity of CASP3 protein]; Deferoxamine inhibits the reaction [Copper Sulfate results in increased secretion of CASP3 protein]; Deferoxamine inhibits the reaction [Manganese results in increased activity of CASP3 protein]
CTD PMID:11933051 PMID:12523938 PMID:16374551 PMID:16800926 PMID:23764342 More... NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp8 caspase 8 increases activity
multiple interactions
ISO Deferoxamine results in increased activity of CASP8 protein
[Glucose co-treated with Deferoxamine] results in increased expression of CASP8 mRNA; Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of CASP8 mRNA]; Nitroprusside inhibits the reaction [Deferoxamine results in increased activity of CASP8 protein]; Vanadates inhibits the reaction [Deferoxamine results in increased activity of CASP8 protein]
CTD PMID:16374551 PMID:33962019 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Casp9 caspase 9 multiple interactions ISO Deferoxamine inhibits the reaction [Asbestos, Amosite results in increased activity of CASP9 protein] CTD PMID:12540492 PMID:14766669 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Cat catalase multiple interactions EXP Deferoxamine inhibits the reaction [Potassium Dichromate results in decreased activity of CAT protein] CTD PMID:22115772 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Cav1 caveolin 1 increases expression ISO Deferoxamine results in increased expression of CAV1 protein CTD PMID:16927372 NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions EXP Deferoxamine inhibits the reaction [[Lipopolysaccharides co-treated with Fructose co-treated with Copper deficiency] results in increased expression of CCL2 protein] CTD PMID:25813056 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Ccna2 cyclin A2 decreases expression ISO Deferoxamine results in decreased expression of CCNA2 protein CTD PMID:11468187 NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577
JBrowse link
G Ccnb1 cyclin B1 decreases expression ISO Deferoxamine results in decreased expression of CCNB1 protein CTD PMID:11468187 NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172
JBrowse link
G Ccnd1 cyclin D1 decreases expression ISO Deferoxamine results in decreased expression of CCND1 protein CTD PMID:11468187 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Ccnd2 cyclin D2 decreases expression ISO Deferoxamine results in decreased expression of CCND2 protein CTD PMID:11468187 NCBI chr 4:159,966,883...159,989,261
Ensembl chr 4:159,962,363...159,989,495
JBrowse link
G Ccnd3 cyclin D3 decreases expression ISO Deferoxamine results in decreased expression of CCND3 protein CTD PMID:11468187 NCBI chr 9:13,394,161...13,400,341
Ensembl chr 9:13,394,169...13,489,371
JBrowse link
G Ccne1 cyclin E1 increases expression ISO Deferoxamine results in increased expression of CCNE1 protein CTD PMID:11468187 NCBI chr 1:90,781,947...90,791,188
Ensembl chr 1:90,781,949...90,791,101
JBrowse link
G Cd36 CD36 molecule decreases expression ISO Deferoxamine results in decreased expression of CD36 protein CTD PMID:24170104 NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903
JBrowse link
G Cdc14a cell division cycle 14A increases expression ISO Deferoxamine results in increased expression of CDC14A mRNA alternative form CTD PMID:16760464 NCBI chr 2:204,225,540...204,380,927
Ensembl chr 2:204,225,540...204,380,927
JBrowse link
G Cdk2 cyclin dependent kinase 2 decreases activity
decreases expression
ISO Deferoxamine results in decreased activity of CDK2 protein
Deferoxamine results in decreased expression of CDK2 protein
CTD PMID:11468187 PMID:17631934 NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression
multiple interactions
decreases expression
ISO
EXP
Deferoxamine results in increased expression of CDKN1A mRNA; Deferoxamine results in increased expression of CDKN1A protein
[Glucose co-treated with Deferoxamine] results in increased expression of CDKN1A mRNA; Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of CDKN1A mRNA]
Deferoxamine results in decreased expression of CDKN1A protein
CTD PMID:10397746 PMID:10559391 PMID:11468187 PMID:12807743 PMID:16227210 More... NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B multiple interactions ISO [Glucose co-treated with Deferoxamine] results in increased expression of CDKN1B mRNA; Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of CDKN1B mRNA] CTD PMID:33962019 NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982
JBrowse link
G Ckb creatine kinase B multiple interactions EXP [Deferoxamine co-treated with Acetylcysteine] inhibits the reaction [Acetaminophen results in decreased activity of CKB protein]; [Deferoxamine co-treated with Acetylcysteine] inhibits the reaction [Carbon Tetrachloride results in decreased activity of CKB protein] CTD PMID:19688255 NCBI chr 6:130,729,420...130,732,301
Ensembl chr 6:130,729,423...130,732,315
JBrowse link
G Col1a1 collagen type I alpha 1 chain multiple interactions EXP Deferoxamine inhibits the reaction [Asbestos, Amosite results in increased expression of COL1A1 mRNA] CTD PMID:11306436 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
JBrowse link
G Cox4i1 cytochrome c oxidase subunit 4i1 multiple interactions ISO Deferoxamine inhibits the reaction [EPAS1 protein results in increased degradation of COX4I1 protein] CTD PMID:18515279 NCBI chr19:48,721,680...48,727,920
Ensembl chr19:48,721,199...48,727,921
JBrowse link
G Cp ceruloplasmin multiple interactions ISO Deferoxamine inhibits the reaction [CP protein results in increased oxidation of 3-carboxy-2,2,5,5-tetramethylpyrrolidin-1-yloxyl] CTD PMID:22824865 NCBI chr 2:102,439,433...102,498,075
Ensembl chr 2:102,439,624...102,498,075
JBrowse link
G Creb1 cAMP responsive element binding protein 1 increases activity EXP Deferoxamine results in increased activity of CREB1 protein CTD PMID:10559391 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
JBrowse link
G Crp C-reactive protein multiple interactions EXP Deferoxamine inhibits the reaction [Copper Sulfate results in increased secretion of CRP protein] CTD PMID:30431687 NCBI chr13:85,131,635...85,175,179
Ensembl chr13:85,124,977...85,175,178
JBrowse link
G Csf2 colony stimulating factor 2 multiple interactions ISO Deferoxamine inhibits the reaction [Particulate Matter results in increased expression of CSF2 mRNA] CTD PMID:20801209 PMID:21703343 NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199
JBrowse link
G Ctnnb1 catenin beta 1 multiple interactions ISO [Oxygen deficiency co-treated with Paclitaxel co-treated with FV-429 compound co-treated with Deferoxamine] affects the localization of CTNNB1 protein; Deferoxamine inhibits the reaction [ferumoxides results in increased activity of CTNNB1 protein] CTD PMID:20338187 PMID:34648812 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
JBrowse link
G Ctsk cathepsin K multiple interactions
decreases expression
ISO Deferoxamine inhibits the reaction [TF protein results in increased expression of CTSK mRNA]; TF protein affects the reaction [Deferoxamine results in decreased expression of CTSK mRNA] CTD PMID:31238089 NCBI chr 2:183,058,586...183,069,551
Ensembl chr 2:183,058,569...183,069,550
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 multiple interactions EXP Deferoxamine promotes the reaction [Asbestos, Amphibole results in increased expression of CXCL2] CTD PMID:21605006 NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075
JBrowse link
G Cycs cytochrome c, somatic multiple interactions
increases expression
ISO [Glucose co-treated with Deferoxamine] results in increased expression of CYCS mRNA; Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of CYCS mRNA]
Deferoxamine results in increased expression of CYCS mRNA
CTD PMID:33962019 NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions ISO Deferoxamine inhibits the reaction [Particulate Matter results in increased expression of CYP1A1 mRNA]
Deferoxamine inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]; ferrous sulfate inhibits the reaction [Deferoxamine inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]]
CTD PMID:10799651 PMID:10823667 PMID:20801209 PMID:21703343 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions EXP Deferoxamine inhibits the reaction [CYP2E1 protein results in increased reduction of tirapazamine] CTD PMID:7710944 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 decreases expression ISO Deferoxamine results in decreased expression of CYP3A4 mRNA; Deferoxamine results in decreased expression of CYP3A4 protein CTD PMID:19695866 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 multiple interactions ISO Deferoxamine promotes the reaction [manganese chloride results in increased expression of DDIT3 protein] CTD PMID:23764342 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
JBrowse link
G Des desmin multiple interactions
increases expression
ISO Deferoxamine inhibits the reaction [Artesunate results in decreased expression of DES mRNA]
Deferoxamine results in increased expression of DES mRNA
CTD PMID:30551460 NCBI chr 9:76,850,979...76,858,695
Ensembl chr 9:76,850,982...76,858,699
JBrowse link
G Diablo diablo, IAP-binding mitochondrial protein increases expression
multiple interactions
ISO Deferoxamine results in increased expression of DIABLO mRNA
[Glucose co-treated with Deferoxamine] results in increased expression of DIABLO mRNA; Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of DIABLO mRNA]
CTD PMID:33962019 NCBI chr12:33,055,784...33,070,400
Ensembl chr12:33,055,263...33,070,387
JBrowse link
G Dicer1 dicer 1 ribonuclease III decreases expression ISO Deferoxamine results in decreased expression of DICER1 mRNA; Deferoxamine results in decreased expression of DICER1 protein CTD PMID:25351418 NCBI chr 6:123,627,529...123,692,278
Ensembl chr 6:123,631,250...123,693,965
JBrowse link
G Dio2 iodothyronine deiodinase 2 increases activity EXP Deferoxamine results in increased activity of DIO2 protein CTD PMID:17615150 NCBI chr 6:109,665,523...109,679,809
Ensembl chr 6:109,665,523...109,679,809
JBrowse link
G Dnm1l dynamin 1-like multiple interactions ISO Deferoxamine inhibits the reaction [ferric ammonium citrate results in decreased phosphorylation of DNM1L protein]
[Glucose co-treated with Deferoxamine] results in increased expression of DNM1L mRNA; Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of DNM1L mRNA]
CTD PMID:26318285 PMID:33962019 NCBI chr11:84,581,216...84,632,382
Ensembl chr11:84,581,216...84,631,482
JBrowse link
G Dnmt1 DNA methyltransferase 1 increases expression
decreases expression
ISO Deferoxamine results in increased expression of DNMT1 mRNA
Deferoxamine results in decreased expression of DNMT1 mRNA
CTD PMID:23483119 NCBI chr 8:19,440,611...19,486,659
Ensembl chr 8:19,440,611...19,486,659
JBrowse link
G Dnmt3a DNA methyltransferase 3 alpha decreases expression
increases expression
ISO Deferoxamine results in decreased expression of DNMT3A mRNA
Deferoxamine results in increased expression of DNMT3A mRNA
CTD PMID:23483119 NCBI chr 6:26,791,517...26,902,161
Ensembl chr 6:26,822,609...26,896,687
JBrowse link
G Dnmt3b DNA methyltransferase 3 beta decreases expression
increases expression
ISO Deferoxamine results in decreased expression of DNMT3B mRNA
Deferoxamine results in increased expression of DNMT3B mRNA
CTD PMID:23483119 NCBI chr 3:142,130,592...142,169,124
Ensembl chr 3:142,130,592...142,169,124
JBrowse link
G Duox1 dual oxidase 1 multiple interactions ISO Deferoxamine inhibits the reaction [Particulate Matter results in increased expression of DUOX1 mRNA] CTD PMID:21703343 NCBI chr 3:109,260,526...109,295,588
Ensembl chr 3:109,262,397...109,295,563
JBrowse link
G Duox2 dual oxidase 2 multiple interactions ISO Deferoxamine inhibits the reaction [Particulate Matter results in increased expression of DUOX2 mRNA] CTD PMID:21703343 NCBI chr 3:109,223,809...109,247,023
Ensembl chr 3:109,226,924...109,245,902
JBrowse link
G Dusp1 dual specificity phosphatase 1 increases expression EXP Deferoxamine results in increased expression of DUSP1 mRNA CTD PMID:11577072 NCBI chr10:16,680,489...16,683,276 JBrowse link
G Edn1 endothelin 1 increases expression EXP Deferoxamine results in increased expression of EDN1 protein CTD PMID:9357851 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885
JBrowse link
G Egfr epidermal growth factor receptor multiple interactions ISO Deferoxamine inhibits the reaction [Asbestos, Crocidolite results in decreased activity of and results in decreased phosphorylation of EGFR protein] CTD PMID:15626777 NCBI chr14:91,176,931...91,349,722
Ensembl chr14:91,177,067...91,344,382
JBrowse link
G Egln1 egl-9 family hypoxia-inducible factor 1 decreases expression ISO Deferoxamine results in decreased expression of EGLN1 protein CTD PMID:22245592 NCBI chr19:52,867,914...52,907,169
Ensembl chr19:52,869,486...52,907,777
JBrowse link
G Ehmt2 euchromatic histone lysine methyltransferase 2 decreases expression ISO Deferoxamine results in decreased expression of EHMT2 mRNA CTD PMID:23483119 NCBI chr20:3,919,623...3,936,751
Ensembl chr20:3,919,624...3,941,547
JBrowse link
G Elane elastase, neutrophil expressed multiple interactions ISO Deferoxamine inhibits the reaction [ELANE protein results in increased expression of MUC5AC mRNA] CTD PMID:11919081 NCBI chr 7:9,817,251...9,819,174
Ensembl chr 7:9,817,252...9,819,100
JBrowse link
G Eno1 enolase 1 increases expression ISO Deferoxamine results in increased expression of ENO1 mRNA CTD PMID:16227210 NCBI chr 5:160,719,951...160,731,337
Ensembl chr 5:160,719,951...160,731,336
JBrowse link
G Epas1 endothelial PAS domain protein 1 multiple interactions
increases expression
increases stability
ISO
EXP
Deferoxamine inhibits the reaction [EPAS1 protein results in increased degradation of COX4I1 protein]
Deferoxamine results in increased expression of EPAS1 protein
Deferoxamine results in increased stability of EPAS1 protein
CTD PMID:18353899 PMID:18515279 PMID:21558026 PMID:27287256 NCBI chr 6:7,790,236...7,871,246
Ensembl chr 6:7,790,647...7,871,228
JBrowse link
G Epo erythropoietin increases expression
increases stability
multiple interactions
ISO
EXP
Deferoxamine results in increased expression of EPO mRNA
Deferoxamine deficiency results in increased expression of EPO mRNA; Deferoxamine results in increased expression of EPO mRNA
Deferoxamine deficiency results in increased stability of EPO mRNA
Deferoxamine results in increased expression of EPO mRNA; Deferoxamine results in increased expression of EPO protein
Deferoxamine inhibits the reaction [Reactive Oxygen Species results in decreased expression of EPO protein]
CTD PMID:9927288 PMID:10559391 PMID:10699462 PMID:10756076 PMID:21558026 NCBI chr12:19,204,258...19,207,948
Ensembl chr12:19,204,508...19,207,946
JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 multiple interactions ISO Deferoxamine promotes the reaction [Palmitic Acid results in increased phosphorylation of ERN1 protein] CTD PMID:32283200 NCBI chr10:91,326,889...91,421,201
Ensembl chr10:91,330,654...91,421,029
JBrowse link
G Ero1a endoplasmic reticulum oxidoreductase 1 alpha increases expression ISO
EXP
Deferoxamine results in increased expression of ERO1A mRNA CTD PMID:12752442 NCBI chr15:18,495,037...18,530,440
Ensembl chr15:18,492,945...18,530,478
JBrowse link
G Erp29 endoplasmic reticulum protein 29 decreases expression
multiple interactions
ISO Deferoxamine results in decreased expression of ERP29 protein
ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of ERP29 protein]
CTD PMID:19515424 NCBI chr12:35,089,698...35,095,952
Ensembl chr12:35,089,707...35,096,376
JBrowse link
G F3 coagulation factor III, tissue factor multiple interactions ISO Deferoxamine inhibits the reaction [ferric ammonium citrate results in increased expression of F3 mRNA] CTD PMID:25858758 NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668
JBrowse link
G Fabp4 fatty acid binding protein 4 decreases expression ISO Deferoxamine results in decreased expression of FABP4 mRNA CTD PMID:12032628 NCBI chr 2:91,580,858...91,585,578
Ensembl chr 2:91,580,885...91,585,578
JBrowse link
G Fasn fatty acid synthase multiple interactions ISO [Paclitaxel co-treated with FV-429 compound co-treated with Deferoxamine] promotes the reaction [Oxygen deficiency results in increased expression of FASN protein]; Deferoxamine promotes the reaction [Oxygen deficiency results in increased expression of FASN protein] CTD PMID:34648812 NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
JBrowse link
G Fech ferrochelatase decreases expression
multiple interactions
ISO Deferoxamine results in decreased expression of FECH protein
ferric chloride inhibits the reaction [Deferoxamine results in decreased expression of FECH protein]
CTD PMID:30517741 NCBI chr18:57,945,123...57,978,327
Ensembl chr18:57,945,122...57,979,348
JBrowse link
G Fis1 fission, mitochondrial 1 multiple interactions ISO [Glucose co-treated with Deferoxamine] results in increased expression of FIS1 mRNA; Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of FIS1 mRNA] CTD PMID:33962019 NCBI chr12:19,708,558...19,723,392
Ensembl chr12:19,708,558...19,723,377
JBrowse link
G Fn1 fibronectin 1 multiple interactions ISO Deferoxamine inhibits the reaction [Artesunate results in decreased expression of FN1 mRNA] CTD PMID:30551460 NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678
JBrowse link
G Fth1 ferritin heavy chain 1 decreases expression
multiple interactions
ISO
EXP
Deferoxamine results in decreased expression of FTH1 protein
Deferoxamine inhibits the reaction [di-n-propyldithiocarbamate results in decreased expression of FTH1 protein]
[Deferoxamine results in decreased abundance of Iron] which results in decreased expression of FTH1 mRNA
CTD PMID:15893546 PMID:16568477 PMID:16777245 PMID:17469137 PMID:32687844 NCBI chr 1:206,627,142...206,629,430
Ensembl chr 1:206,627,103...206,725,424
JBrowse link
G Ftl1 ferritin light chain 1 multiple interactions
decreases expression
ISO
EXP
[Deferoxamine results in decreased abundance of Iron] which results in decreased expression of FTL mRNA; Deferoxamine inhibits the reaction [Doxorubicin promotes the reaction [Iron binds to [FTL protein binds to FTMT protein]]]; Deferoxamine inhibits the reaction [Iron binds to [FTL protein binds to FTMT protein]]
Deferoxamine results in decreased expression of FTL1 protein
CTD PMID:12393473 PMID:12644586 PMID:15893546 PMID:16568477 NCBI chr 1:95,936,390...95,938,234
Ensembl chr 1:95,936,387...95,939,725
JBrowse link
G Ftmt ferritin mitochondrial multiple interactions ISO Deferoxamine inhibits the reaction [Doxorubicin promotes the reaction [Iron binds to [FTL protein binds to FTMT protein]]]; Deferoxamine inhibits the reaction [Iron binds to [FTL protein binds to FTMT protein]] CTD PMID:12644586 NCBI chr18:45,758,874...45,760,123
Ensembl chr18:45,758,874...45,760,123
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha increases expression ISO Deferoxamine results in increased expression of GADD45A mRNA CTD PMID:10397746 PMID:11468187 NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115
JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase decreases expression
multiple interactions
ISO Deferoxamine results in decreased expression of GAPDH protein
ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of GAPDH protein]
CTD PMID:19515424 NCBI chr 4:157,962,312...157,967,158
Ensembl chr 4:157,962,343...157,966,235
JBrowse link
G Gas1 growth arrest-specific 1 multiple interactions ISO [Deferoxamine results in decreased abundance of Iron] which results in decreased expression of GAS1 mRNA CTD PMID:12393473 NCBI chr17:4,482,014...4,485,155 JBrowse link
G Gbe1 1,4-alpha-glucan branching enzyme 1 increases expression ISO Deferoxamine results in increased expression of GBE1 mRNA CTD PMID:15094311 NCBI chr11:8,734,806...9,000,226
Ensembl chr11:8,734,820...9,000,210
JBrowse link
G Gck glucokinase affects expression EXP Deferoxamine affects the expression of GCK mRNA CTD PMID:9761743 NCBI chr14:80,785,060...80,829,842
Ensembl chr14:80,785,060...80,826,995
JBrowse link
G Glo1 glyoxalase 1 increases expression
multiple interactions
ISO Deferoxamine results in increased expression of GLO1 protein
ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of GLO1 protein]
CTD PMID:19515424 NCBI chr20:8,663,617...8,681,661
Ensembl chr20:8,662,801...8,681,649
JBrowse link
G Gosr1 golgi SNAP receptor complex member 1 multiple interactions ISO GOSR1 protein affects the reaction [Deferoxamine inhibits the reaction [Nitroprusside results in decreased phosphorylation of MAPK1 protein]]; GOSR1 protein affects the reaction [Deferoxamine inhibits the reaction [Nitroprusside results in decreased phosphorylation of MAPK3 protein]] CTD PMID:31066958 NCBI chr10:61,570,499...61,607,287
Ensembl chr10:61,450,494...61,607,177
Ensembl chr10:61,450,494...61,607,177
JBrowse link
G Gpx4 glutathione peroxidase 4 multiple interactions ISO Deferoxamine inhibits the reaction [Busulfan results in decreased expression of GPX4 protein] CTD PMID:32416107 NCBI chr 7:9,650,186...9,652,982
Ensembl chr 7:9,650,185...9,652,982
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions
decreases phosphorylation
ISO Deferoxamine inhibits the reaction [Fenretinide results in increased phosphorylation of GSK3B protein]
Deferoxamine results in decreased phosphorylation of GSK3B protein
CTD PMID:25246272 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions EXP Deferoxamine inhibits the reaction [Potassium Dichromate results in decreased activity of GSR protein] CTD PMID:22115772 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
JBrowse link
G Hamp hepcidin antimicrobial peptide multiple interactions
decreases expression
affects expression
ISO
EXP
Deferoxamine inhibits the reaction [BMP6 protein results in increased expression of HAMP mRNA]; Deferoxamine promotes the reaction [ferric ammonium citrate results in decreased expression of HAMP mRNA]; ferric ammonium citrate affects the reaction [Deferoxamine inhibits the reaction [BMP6 protein results in increased expression of HAMP mRNA]]
Deferoxamine results in decreased expression of HAMP protein
Deferoxamine affects the expression of HAMP mRNA
CTD PMID:21558026 PMID:25633564 NCBI chr 1:86,170,926...86,172,865
Ensembl chr 1:86,170,901...86,172,891
JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 multiple interactions EXP Deferoxamine inhibits the reaction [Copper Sulfate results in increased expression of HAVCR1 protein] CTD PMID:30431687 NCBI chr10:31,118,667...31,151,730
Ensembl chr10:31,119,088...31,151,698
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha multiple interactions
increases expression
increases stability
increases activity
decreases degradation
affects localization
ISO
EXP
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Deferoxamine results in increased expression of HIF1A protein]; 3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole inhibits the reaction [Deferoxamine results in increased expression of HIF1A protein]; [Deferoxamine results in decreased abundance of Iron] which results in increased expression of HIF1A mRNA; [Doxorubicin co-treated with Deferoxamine] results in increased expression of HIF1A protein; [Glucose co-treated with Deferoxamine] results in increased expression of HIF1A mRNA; [Paclitaxel co-treated with FV-429 compound co-treated with Deferoxamine] promotes the reaction [Oxygen deficiency results in increased expression of HIF1A protein]; Arsenic Trioxide promotes the reaction [Deferoxamine results in increased expression of HIF1A protein]; Cadmium inhibits the reaction [Deferoxamine results in increased expression of HIF1A protein]; Deferoxamine promotes the reaction [[HIF1A protein binds to VEGFA promoter] which results in increased expression of VEGFA mRNA]; Deferoxamine promotes the reaction [Oxygen deficiency results in increased expression of HIF1A protein]; Deferoxamine results in increased expression of and results in increased stability of HIF1A protein; Deferoxamine results in increased stability of and results in increased expression of HIF1A protein; dihydrotanshinone I inhibits the reaction [Deferoxamine results in increased expression of HIF1A protein]; ferric citrate inhibits the reaction [Deferoxamine results in increased expression of HIF1A protein]; Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of HIF1A mRNA]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [Deferoxamine results in increased expression of HIF1A protein]; ST6GAL1 protein promotes the reaction [Deferoxamine results in increased expression of HIF1A protein]; TP53 gene mutant form promotes the reaction [Deferoxamine results in increased expression of HIF1A protein]
Deferoxamine results in increased expression of HIF1A mRNA; Deferoxamine results in increased expression of HIF1A protein
Deferoxamine results in increased stability of HIF1A protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Deferoxamine results in increased expression of HIF1A protein]; ferric citrate inhibits the reaction [Deferoxamine results in increased expression of HIF1A protein]
Deferoxamine results in increased activity of HIF1A protein
[Deferoxamine results in increased activity of HIF1A protein] which results in decreased susceptibility to Carmustine
Deferoxamine results in decreased degradation of HIF1A protein
Deferoxamine affects the localization of HIF1A protein
CTD PMID:10559391 PMID:10866824 PMID:11286986 PMID:12393473 PMID:14604972 More... NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
JBrowse link
G Hif3a hypoxia inducible factor 3 subunit alpha increases expression ISO Deferoxamine results in increased expression of HIF3A protein CTD PMID:16775626 NCBI chr 1:77,718,110...77,750,448
Ensembl chr 1:77,722,471...77,749,758
JBrowse link
G Hk2 hexokinase 2 increases expression
multiple interactions
ISO Deferoxamine results in increased expression of HK2 protein
Doxorubicin inhibits the reaction [Deferoxamine results in increased expression of HK2 protein]
CTD PMID:34126102 NCBI chr 4:115,234,509...115,283,530
Ensembl chr 4:115,234,509...115,283,530
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
decreases degradation
decreases expression
ISO
EXP
Deferoxamine inhibits the reaction [HMOX1 protein results in increased abundance of Superoxides]
Deferoxamine results in decreased degradation of HMOX1 protein
Deferoxamine results in decreased expression of HMOX1 mRNA
[Deferoxamine results in decreased abundance of Iron] which results in decreased expression of HMOX1 mRNA; Deferoxamine inhibits the reaction [Cadmium Chloride results in increased activity of HMOX1 protein]; Deferoxamine inhibits the reaction [Cadmium Chloride results in increased expression of HMOX1 mRNA]; Deferoxamine inhibits the reaction [Cadmium Chloride results in increased expression of HMOX1 protein]; Deferoxamine inhibits the reaction [Ethacrynic Acid affects the localization of HMOX1 protein]; Deferoxamine inhibits the reaction [Ethacrynic Acid results in increased expression of HMOX1 mRNA]; Deferoxamine inhibits the reaction [Fenretinide results in increased expression of HMOX1 protein]; Deferoxamine inhibits the reaction [Oxygen results in increased expression of HMOX1 mRNA]; Deferoxamine inhibits the reaction [phenethyl isothiocyanate results in increased expression of HMOX1 mRNA]; Deferoxamine inhibits the reaction [phenethyl isothiocyanate results in increased expression of HMOX1 protein]; Deferoxamine inhibits the reaction [sulforaphane results in increased expression of HMOX1 mRNA]; Deferoxamine inhibits the reaction [Zinc results in increased expression of HMOX1 mRNA]; Deferoxamine inhibits the reaction [Zinc results in increased expression of HMOX1 protein]; ferrous sulfate inhibits the reaction [Deferoxamine inhibits the reaction [Cadmium Chloride results in increased activity of HMOX1 protein]]; ferrous sulfate inhibits the reaction [Deferoxamine inhibits the reaction [Cadmium Chloride results in increased expression of HMOX1 mRNA]]; ferrous sulfate inhibits the reaction [Deferoxamine inhibits the reaction [phenethyl isothiocyanate results in increased expression of HMOX1 mRNA]]; ferrous sulfate inhibits the reaction [Deferoxamine inhibits the reaction [phenethyl isothiocyanate results in increased expression of HMOX1 protein]]; ferrous sulfate inhibits the reaction [Deferoxamine inhibits the reaction [sulforaphane results in increased expression of HMOX1 mRNA]]
Deferoxamine inhibits the reaction [HMOX1 protein results in increased abundance of Superoxides]; Deferoxamine inhibits the reaction [Nitroprusside results in increased expression of HMOX1 protein]
CTD PMID:9747510 PMID:10814519 PMID:12393473 PMID:16439612 PMID:18073186 More... NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A multiple interactions
decreases expression
ISO ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of HSPA1A protein]
Deferoxamine results in decreased expression of HSPA1A protein
CTD PMID:19515424
G Hspa1l heat shock protein family A (Hsp70) member 1 like multiple interactions ISO [Deferoxamine results in decreased abundance of Iron] which results in decreased expression of HSPA1L mRNA CTD PMID:12393473 NCBI chr20:3,848,843...3,855,571
Ensembl chr20:3,848,843...3,855,571
JBrowse link
G Hspa9 heat shock protein family A (Hsp70) member 9 multiple interactions ISO [Deferoxamine results in decreased abundance of Iron] which results in decreased expression of HSPA9 mRNA CTD PMID:12393473 NCBI chr18:26,536,131...26,554,294
Ensembl chr18:26,535,798...26,554,292
JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 multiple interactions
decreases expression
ISO ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of HSPD1 protein]
Deferoxamine results in decreased expression of HSPD1 protein
CTD PMID:19515424 PMID:24170104 NCBI chr 9:56,579,195...56,590,011
Ensembl chr 9:56,579,201...56,589,662
JBrowse link
G Hsph1 heat shock protein family H (Hsp110) member 1 multiple interactions ISO [Deferoxamine results in decreased abundance of Iron] which results in decreased expression of HSPH1 mRNA CTD PMID:12393473 NCBI chr12:5,390,916...5,410,224
Ensembl chr12:5,390,922...5,410,224
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO [Deferoxamine affects the abundance of Iron] inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]; [Deferoxamine affects the abundance of Iron] inhibits the reaction [TNF protein results in increased expression of ICAM1 protein] CTD PMID:12633744 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Il10 interleukin 10 multiple interactions EXP Deferoxamine inhibits the reaction [Copper Sulfate results in decreased secretion of IL10 protein] CTD PMID:30431687 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
JBrowse link
G Il1a interleukin 1 alpha multiple interactions ISO Deferoxamine inhibits the reaction [Particulate Matter results in increased expression of IL1A mRNA] CTD PMID:21703343 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
JBrowse link
G Il1b interleukin 1 beta multiple interactions
increases expression
decreases expression
ISO Deferoxamine inhibits the reaction [Particulate Matter results in increased expression of IL1B mRNA]; Deferoxamine promotes the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]; ferric chloride inhibits the reaction [Deferoxamine promotes the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]]
Deferoxamine results in increased expression of IL1B mRNA
Deferoxamine inhibits the reaction [Asbestos, Crocidolite results in increased secretion of IL1B protein]
Deferoxamine results in decreased expression of IL1B mRNA
CTD PMID:9851740 PMID:18403674 PMID:20801209 PMID:32816093 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il4 interleukin 4 multiple interactions EXP Deferoxamine inhibits the reaction [Mercuric Chloride results in increased expression of IL4 mRNA] CTD PMID:11222498 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
JBrowse link
G Il6 interleukin 6 multiple interactions ISO
EXP
Deferoxamine inhibits the reaction [2,2',4,4'-tetrabromodiphenyl ether results in increased expression of and results in increased secretion of IL6 protein]; Deferoxamine inhibits the reaction [Coal Ash results in increased expression of IL6 protein]
Deferoxamine inhibits the reaction [Asbestos, Amphibole results in increased expression of IL6 mRNA]
CTD PMID:9344885 PMID:22168577 PMID:24296301 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Ireb2 iron responsive element binding protein 2 increases expression
increases activity
multiple interactions
EXP
ISO
Deferoxamine results in increased expression of IREB2 protein
Deferoxamine results in increased activity of IREB2 protein
Deferoxamine inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased activity of IREB2 protein]; Deferoxamine results in increased expression of and results in increased activity of IREB2 protein
CTD PMID:10397746 PMID:11054110 PMID:16135072 PMID:16568477 PMID:17469137 More... NCBI chr 8:55,228,080...55,311,613
Ensembl chr 8:55,228,085...55,311,611
JBrowse link
G Itgb3 integrin subunit beta 3 decreases expression
multiple interactions
ISO Deferoxamine results in decreased expression of ITGB3 mRNA
Deferoxamine inhibits the reaction [TF protein results in increased expression of ITGB3 mRNA]
CTD PMID:31238089 NCBI chr10:89,509,917...89,564,679
Ensembl chr10:89,509,989...89,564,679
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO [Deferoxamine results in decreased abundance of Iron] which results in increased expression of JUN mRNA CTD PMID:12393473 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
JBrowse link
G Kdm1a lysine demethylase 1A multiple interactions ISO Deferoxamine results in decreased expression of and results in decreased activity of KDM1A protein CTD PMID:23483119 NCBI chr 5:148,782,976...148,838,319
Ensembl chr 5:148,782,976...148,838,319
JBrowse link
G Kdm3a lysine demethylase 3A increases expression ISO Deferoxamine results in increased expression of KDM3A protein CTD PMID:23546878 NCBI chr 4:103,630,907...103,675,073
Ensembl chr 4:103,630,908...103,675,073
JBrowse link
G Kdm4a lysine demethylase 4A multiple interactions ISO Deferoxamine results in decreased expression of and results in decreased activity of KDM4A protein CTD PMID:23483119 NCBI chr 5:131,672,754...131,719,534
Ensembl chr 5:131,672,754...131,719,501
JBrowse link
G Kdr kinase insert domain receptor multiple interactions ISO [Glucose co-treated with Deferoxamine] results in increased expression of KDR mRNA; Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of KDR mRNA] CTD PMID:33962019 NCBI chr14:32,217,871...32,261,018
Ensembl chr14:32,217,871...32,261,018
JBrowse link
G Lcn2 lipocalin 2 multiple interactions
increases expression
ISO Deferoxamine affects the reaction [Magnetite Nanoparticles results in increased expression of LCN2 mRNA]; Deferoxamine inhibits the reaction [LCN2 protein results in decreased secretion of VEGFA protein]
Deferoxamine results in increased expression of LCN2 mRNA
CTD PMID:17114340 PMID:23086747 NCBI chr 3:15,680,688...15,684,033
Ensembl chr 3:15,680,687...15,684,095
JBrowse link
G Lep leptin increases expression
increases secretion
ISO
EXP
Deferoxamine results in increased expression of LEP mRNA
Deferoxamine results in increased secretion of LEP protein
CTD PMID:12032628 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
JBrowse link
G Lipe lipase E, hormone sensitive type decreases expression ISO Deferoxamine results in decreased expression of LIPE mRNA CTD PMID:12032628 NCBI chr 1:80,965,612...80,984,313
Ensembl chr 1:80,965,627...80,984,310
JBrowse link
G Lox lysyl oxidase multiple interactions ISO [Deferoxamine results in decreased abundance of Iron] which results in increased expression of LOX mRNA CTD PMID:12393473 NCBI chr18:45,964,311...46,041,477
Ensembl chr18:45,967,343...46,041,477
JBrowse link
G Map1lc3a microtubule-associated protein 1 light chain 3 alpha multiple interactions ISO Deferoxamine inhibits the reaction [Hydrogen Peroxide affects the localization of MAP1LC3A protein] CTD PMID:21742779 NCBI chr 3:143,783,024...143,784,670
Ensembl chr 3:143,783,024...143,784,670
JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta increases expression
multiple interactions
ISO Deferoxamine results in increased expression of MAP1LC3B protein
Deferoxamine inhibits the reaction [di-n-propyldithiocarbamate results in increased expression of and results in increased lipidation of MAP1LC3B protein]; Iron affects the reaction [Deferoxamine results in increased expression of MAP1LC3B protein]
CTD PMID:25301941 PMID:32687844 NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690
JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 multiple interactions ISO Deferoxamine inhibits the reaction [Plant Extracts results in increased phosphorylation of MAP3K5 protein] CTD PMID:20206247 NCBI chr 1:14,685,776...14,904,935
Ensembl chr 1:14,685,492...14,904,800
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
increases phosphorylation
EXP
ISO
Deferoxamine inhibits the reaction [PDGFB protein results in increased phosphorylation of MAPK1 protein]; Deferoxamine promotes the reaction [Manganese results in increased phosphorylation of MAPK1 protein]
Deferoxamine inhibits the reaction [Nitroprusside results in decreased phosphorylation of MAPK1 protein]; GOSR1 protein affects the reaction [Deferoxamine inhibits the reaction [Nitroprusside results in decreased phosphorylation of MAPK1 protein]]
[Deferoxamine co-treated with TNFSF11 protein] results in decreased phosphorylation of MAPK1 protein; Deferoxamine inhibits the reaction [[Hydrogen Peroxide co-treated with TNFSF11 protein] results in increased phosphorylation of MAPK1 protein]
Deferoxamine results in increased phosphorylation of MAPK1 protein
CTD PMID:11933051 PMID:16527254 PMID:18032466 PMID:20368581 PMID:31066958 More... NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
increases phosphorylation
EXP
ISO
Deferoxamine inhibits the reaction [PDGFB protein results in increased phosphorylation of MAPK3 protein]; Deferoxamine promotes the reaction [Manganese results in increased phosphorylation of MAPK3 protein]
Deferoxamine inhibits the reaction [Nitroprusside results in decreased phosphorylation of MAPK3 protein]; GOSR1 protein affects the reaction [Deferoxamine inhibits the reaction [Nitroprusside results in decreased phosphorylation of MAPK3 protein]]
[Deferoxamine co-treated with TNFSF11 protein] results in decreased phosphorylation of MAPK3 protein; Deferoxamine inhibits the reaction [[Hydrogen Peroxide co-treated with TNFSF11 protein] results in increased phosphorylation of MAPK3 protein]
Deferoxamine results in increased phosphorylation of MAPK3 protein
CTD PMID:11933051 PMID:16527254 PMID:18032466 PMID:20368581 PMID:31066958 More... NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 increases phosphorylation
multiple interactions
ISO Deferoxamine results in increased phosphorylation of MAPK8 protein
Deferoxamine inhibits the reaction [Plant Extracts results in increased phosphorylation of MAPK8 protein]
CTD PMID:20206247 PMID:20368581 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 increases phosphorylation
multiple interactions
ISO Deferoxamine results in increased phosphorylation of MAPK9 protein
Deferoxamine inhibits the reaction [Plant Extracts results in increased phosphorylation of MAPK9 protein]
CTD PMID:20206247 PMID:20368581 NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178
JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member multiple interactions
increases cleavage
ISO Nitroprusside inhibits the reaction [Deferoxamine results in increased cleavage of MCL1 protein]; Vanadates inhibits the reaction [Deferoxamine results in increased cleavage of MCL1 protein] CTD PMID:16374551 NCBI chr 2:183,219,137...183,235,676
Ensembl chr 2:183,219,220...183,222,303
JBrowse link
G Mff mitochondrial fission factor increases expression
multiple interactions
ISO Deferoxamine results in increased expression of MFF mRNA
[Glucose co-treated with Deferoxamine] results in increased expression of MFF mRNA; Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of MFF mRNA]
CTD PMID:33962019 NCBI chr 9:84,007,798...84,036,039
Ensembl chr 9:84,007,798...84,036,039
JBrowse link
G Mfn2 mitofusin 2 multiple interactions ISO [Glucose co-treated with Deferoxamine] results in decreased expression of MFN2 mRNA; Melatonin affects the reaction [[Glucose co-treated with Deferoxamine] results in decreased expression of MFN2 mRNA] CTD PMID:33962019 NCBI chr 5:158,304,285...158,335,502
Ensembl chr 5:158,304,287...158,335,342
JBrowse link
G Mief2 mitochondrial elongation factor 2 multiple interactions
increases expression
ISO [Glucose co-treated with Deferoxamine] results in increased expression of MIEF2 mRNA; Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of MIEF2 mRNA]
Deferoxamine results in increased expression of MIEF2 mRNA
CTD PMID:33962019 NCBI chr10:45,408,055...45,414,144
Ensembl chr10:45,408,082...45,414,144
JBrowse link
G Mir210 microRNA 210 increases expression ISO Deferoxamine results in increased expression of MIR210 mRNA CTD PMID:24577088 NCBI chr 1:196,326,343...196,326,452
Ensembl chr 1:196,326,337...196,326,454
JBrowse link
G Mmp1 matrix metallopeptidase 1 multiple interactions ISO [Deferoxamine co-treated with SOD2 protein] results in increased expression of MMP1 mRNA; Deferoxamine inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of MMP1 mRNA]; Deferoxamine inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of MMP1 protein]; Deferoxamine inhibits the reaction [[Amitrole co-treated with SOD2 protein] results in increased expression of MMP1 mRNA]; Deferoxamine inhibits the reaction [[Buthionine Sulfoximine co-treated with SOD2 protein] results in increased expression of MMP1 mRNA] CTD PMID:10464329 PMID:19136476 NCBI chr 8:4,658,588...4,679,099
Ensembl chr 8:4,658,588...4,679,097
JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions
decreases activity
ISO Calcium Chloride inhibits the reaction [Deferoxamine results in decreased activity of MMP2 protein]; Deferoxamine inhibits the reaction [ferumoxides results in increased activity of MMP2 protein]; ferric chloride inhibits the reaction [Deferoxamine results in decreased activity of MMP2 protein] CTD PMID:10086886 PMID:20338187 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions
decreases expression
ISO Deferoxamine inhibits the reaction [TF protein results in increased expression of MMP9 mRNA]; TF protein affects the reaction [Deferoxamine results in increased expression of MMP9 mRNA]
Deferoxamine results in decreased expression of MMP9 mRNA
CTD PMID:31238089 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
JBrowse link
G Mrps9 mitochondrial ribosomal protein S9 multiple interactions
increases expression
ISO ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of MRPS9 protein] CTD PMID:19515424 NCBI chr 9:45,113,554...45,172,375
Ensembl chr 9:45,113,554...45,172,375
JBrowse link
G Msr1 macrophage scavenger receptor 1 multiple interactions ISO Deferoxamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MSR1 mRNA] CTD PMID:9614211 NCBI chr16:52,717,775...52,802,890
Ensembl chr16:52,717,732...52,799,676
JBrowse link
G Mt-atp6 mitochondrially encoded ATP synthase membrane subunit 6 decreases expression ISO Deferoxamine results in decreased expression of ATP6 mRNA CTD PMID:31238089 NCBI chr MT:7,919...8,599
Ensembl chr MT:7,919...8,599
JBrowse link
G Mt-atp8 mitochondrially encoded ATP synthase membrane subunit 8 decreases expression ISO Deferoxamine results in decreased expression of ATP8 mRNA CTD PMID:31238089 NCBI chr MT:7,758...7,961
Ensembl chr MT:7,758...7,961
JBrowse link
G Mt-co1 mitochondrially encoded cytochrome c oxidase I decreases expression ISO Deferoxamine results in decreased expression of COX1 mRNA CTD PMID:31238089 NCBI chr MT:5,323...6,867
Ensembl chr MT:5,323...6,867
JBrowse link
G Mt-co2 mitochondrially encoded cytochrome c oxidase II decreases expression ISO Deferoxamine results in decreased expression of COX2 mRNA CTD PMID:31238089 NCBI chr MT:7,006...7,689
Ensembl chr MT:7,006...7,689
JBrowse link
G Mt-co3 mitochondrially encoded cytochrome c oxidase III decreases expression ISO Deferoxamine results in decreased expression of COX3 mRNA CTD PMID:31238089 NCBI chr MT:8,599...9,382
Ensembl chr MT:8,599...9,382
JBrowse link
G Mt-cyb mitochondrially encoded cytochrome b decreases expression ISO Deferoxamine results in decreased expression of CYTB mRNA CTD PMID:31238089 NCBI chr MT:14,136...15,278
Ensembl chr MT:14,136...15,278
JBrowse link
G Mt-nd1 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 1 decreases expression ISO Deferoxamine results in decreased expression of ND1 mRNA CTD PMID:31238089 NCBI chr MT:2,740...3,694
Ensembl chr MT:2,740...3,694
JBrowse link
G Mt-nd2 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 2 decreases expression ISO Deferoxamine results in decreased expression of ND2 mRNA CTD PMID:31238089 NCBI chr MT:3,904...4,942
Ensembl chr MT:3,904...4,942
JBrowse link
G Mt-nd3 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 3 decreases expression ISO Deferoxamine results in decreased expression of ND3 mRNA CTD PMID:31238089 NCBI chr MT:9,451...9,798
Ensembl chr MT:9,451...9,798
JBrowse link
G Mt-nd4 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 4 decreases expression ISO Deferoxamine results in decreased expression of ND4 mRNA CTD PMID:31238089 NCBI chr MT:10,160...11,537
Ensembl chr MT:10,160...11,537
JBrowse link
G Mt-nd4l mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 4L decreases expression ISO Deferoxamine results in decreased expression of ND4L mRNA CTD PMID:31238089 NCBI chr MT:9,870...10,166
Ensembl chr MT:9,870...10,166
JBrowse link
G Mt-nd5 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 5 decreases expression ISO Deferoxamine results in decreased expression of ND5 mRNA CTD PMID:31238089 NCBI chr MT:11,736...13,565
Ensembl chr MT:11,736...13,565
JBrowse link
G Mt-nd6 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 6 decreases expression ISO Deferoxamine results in decreased expression of ND6 mRNA CTD PMID:31238089 NCBI chr MT:13,543...14,061
Ensembl chr MT:13,543...14,061
JBrowse link
G Mt2A metallothionein 2A multiple interactions ISO [Deferoxamine results in decreased abundance of Iron] which results in increased expression of MT2A mRNA CTD PMID:12393473 NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784
JBrowse link
G Muc5ac mucin 5AC, oligomeric mucus/gel-forming multiple interactions ISO Deferoxamine inhibits the reaction [ELANE protein results in increased expression of MUC5AC mRNA] CTD PMID:11919081 NCBI chr 1:196,864,375...196,896,475
Ensembl chr 1:196,864,336...196,896,475
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor increases degradation
decreases expression
multiple interactions
ISO Deferoxamine results in increased degradation of MYC protein
Deferoxamine results in decreased expression of MYC protein
[Deferoxamine results in decreased abundance of Iron] which results in decreased expression of MYC mRNA
CTD PMID:12393473 PMID:20046830 PMID:22245592 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
JBrowse link
G Ncoa4 nuclear receptor coactivator 4 multiple interactions ISO Deferoxamine inhibits the reaction [di-n-propyldithiocarbamate results in increased expression of NCOA4 protein]; Deferoxamine promotes the reaction [Palmitic Acid results in increased expression of NCOA4 protein] CTD PMID:32283200 PMID:32687844 NCBI chr16:7,389,222...7,409,564
Ensembl chr16:7,366,542...7,409,556
Ensembl chr16:7,366,542...7,409,556
JBrowse link
G Ndrg1 N-myc downstream regulated 1 increases expression
decreases response to substance
ISO Deferoxamine results in increased expression of NDRG1 mRNA; Deferoxamine results in increased expression of NDRG1 protein
NDRG1 protein results in decreased susceptibility to Deferoxamine
CTD PMID:11006124 PMID:24532803 NCBI chr 7:98,684,487...98,725,869
Ensembl chr 7:98,684,487...98,725,880
JBrowse link
G Ndufb8 NADH:ubiquinone oxidoreductase subunit B8 decreases expression ISO Deferoxamine results in decreased expression of NDUFB8 protein CTD PMID:31238089 NCBI chr 1:243,408,659...243,413,701
Ensembl chr 1:243,408,619...243,413,817
JBrowse link
G Nes nestin decreases expression ISO Deferoxamine results in decreased expression of NES mRNA CTD PMID:16772336 NCBI chr 2:173,437,867...173,447,777
Ensembl chr 2:173,438,734...173,447,777
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions ISO Deferoxamine inhibits the reaction [Nitroprusside results in decreased expression of NFE2L2 protein]; Deferoxamine inhibits the reaction [phenethyl isothiocyanate results in increased expression of and affects the localization of NFE2L2 protein]; ferrous sulfate inhibits the reaction [Deferoxamine inhibits the reaction [Ethacrynic Acid affects the localization of NFE2L2 protein]]; ferrous sulfate inhibits the reaction [Deferoxamine inhibits the reaction [phenethyl isothiocyanate results in increased expression of and affects the localization of NFE2L2 protein]]
Deferoxamine inhibits the reaction [Busulfan results in decreased expression of NFE2L2 protein]
CTD PMID:26945724 PMID:31066958 PMID:32416107 NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions EXP Deferoxamine inhibits the reaction [Copper Sulfate results in increased expression of NFKBIA mRNA] CTD PMID:30431687 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions
increases expression
EXP
ISO
Nitrites inhibits the reaction [[TNF protein results in increased activity of NOS2 protein] which results in increased chemical synthesis of Deferoxamine]
[Deferoxamine results in increased expression of NOS2 mRNA] which results in increased abundance of Nitric Oxide
CTD PMID:7532384 PMID:18073202 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 decreases expression
multiple interactions
ISO Deferoxamine results in decreased expression of NQO1 mRNA
Deferoxamine inhibits the reaction [Benzo(a)pyrene results in increased expression of NQO1 mRNA]
CTD PMID:14645679 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Olr1 oxidized low density lipoprotein receptor 1 decreases expression ISO Deferoxamine results in decreased expression of OLR1 protein CTD PMID:24170104 NCBI chr 4:162,926,436...162,949,057
Ensembl chr 4:162,926,439...162,948,523
JBrowse link
G Opa1 OPA1, mitochondrial dynamin like GTPase multiple interactions
increases expression
ISO [Glucose co-treated with Deferoxamine] results in increased expression of OPA1 mRNA; Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of OPA1 mRNA]
Deferoxamine results in increased expression of OPA1 mRNA
CTD PMID:33962019 NCBI chr11:71,108,100...71,185,170
Ensembl chr11:71,109,873...71,185,109
JBrowse link
G P4ha1 prolyl 4-hydroxylase subunit alpha 1 decreases expression
multiple interactions
ISO Deferoxamine results in decreased expression of P4HA1 protein
ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of P4HA1 protein]
CTD PMID:19515424 NCBI chr20:27,302,046...27,352,098
Ensembl chr20:27,302,141...27,352,786
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage
multiple interactions
ISO Deferoxamine results in increased cleavage of PARP1 protein
Indomethacin promotes the reaction [Deferoxamine results in increased cleavage of PARP1 protein]; Sulindac promotes the reaction [Deferoxamine results in increased cleavage of PARP1 protein]
CTD PMID:21882223 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Pdgfa platelet derived growth factor subunit A multiple interactions EXP Deferoxamine inhibits the reaction [Asbestos, Amosite results in increased expression of PDGFA mRNA] CTD PMID:11306436 NCBI chr12:15,645,549...15,667,056
Ensembl chr12:15,645,541...15,666,497
JBrowse link
G Pdgfb platelet derived growth factor subunit B multiple interactions EXP Deferoxamine inhibits the reaction [PDGFB protein results in increased phosphorylation of AKT1 protein]; Deferoxamine inhibits the reaction [PDGFB protein results in increased phosphorylation of MAPK1 protein]; Deferoxamine inhibits the reaction [PDGFB protein results in increased phosphorylation of MAPK3 protein] CTD PMID:18032466 NCBI chr 7:111,539,444...111,557,984
Ensembl chr 7:111,540,345...111,557,984
JBrowse link
G Pdgfrb platelet derived growth factor receptor beta decreases expression EXP Deferoxamine results in decreased expression of PDGFRB protein CTD PMID:18032466 NCBI chr18:54,500,002...54,538,843
Ensembl chr18:54,499,964...54,538,843
JBrowse link
G Pdhb pyruvate dehydrogenase E1 subunit beta increases expression
multiple interactions
ISO Deferoxamine results in increased expression of PDHB protein
ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of PDHB protein]
CTD PMID:19515424 NCBI chr15:16,752,561...16,758,503
Ensembl chr15:16,750,980...16,758,500
JBrowse link
G Pdk1 pyruvate dehydrogenase kinase 1 increases expression ISO Deferoxamine results in increased expression of PDK1 mRNA CTD PMID:21558026 NCBI chr 3:56,705,824...56,733,040
Ensembl chr 3:56,705,871...56,733,038
JBrowse link
G Pfkfb4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 multiple interactions ISO [Deferoxamine results in decreased abundance of Iron] which results in increased expression of PFKFB4 mRNA CTD PMID:16025159 NCBI chr 8:109,643,558...109,687,006
Ensembl chr 8:109,643,937...109,685,634
JBrowse link
G Pgk1 phosphoglycerate kinase 1 multiple interactions
decreases expression
ISO ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of PGK1 protein]
Deferoxamine results in decreased expression of PGK1 protein
CTD PMID:19515424 NCBI chr  X:71,271,454...71,287,429
Ensembl chr  X:71,271,440...71,287,418
JBrowse link
G Pink1 PTEN induced kinase 1 multiple interactions ISO [Glucose co-treated with Deferoxamine] results in increased expression of PINK1 mRNA; Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of PINK1 mRNA] CTD PMID:33962019 NCBI chr 5:150,530,523...150,542,635
Ensembl chr 5:150,530,523...150,542,635
JBrowse link
G Plagl2 PLAG1 like zinc finger 2 multiple interactions ISO Deferoxamine results in increased expression of and affects the localization of PLAGL2 protein CTD PMID:11832486 NCBI chr 3:141,695,322...141,708,567
Ensembl chr 3:141,695,322...141,708,503
JBrowse link
G Plau plasminogen activator, urokinase multiple interactions ISO Deferoxamine inhibits the reaction [ferric nitrilotriacetate results in increased activity of PLAU mRNA]; Deferoxamine inhibits the reaction [ferric nitrilotriacetate results in increased expression of PLAU mRNA] CTD PMID:17571974 NCBI chr15:3,456,230...3,462,732
Ensembl chr15:3,456,232...3,462,775
JBrowse link
G Plin2 perilipin 2 multiple interactions ISO [Paclitaxel co-treated with FV-429 compound co-treated with Deferoxamine] promotes the reaction [Oxygen deficiency results in increased expression of PLIN2 protein]; Deferoxamine promotes the reaction [Oxygen deficiency results in increased expression of PLIN2 protein] CTD PMID:34648812 NCBI chr 5:101,156,643...101,211,738
Ensembl chr 5:101,154,411...101,242,319
JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 increases expression
multiple interactions
ISO Deferoxamine results in increased expression of PMAIP1 mRNA
[Glucose co-treated with Deferoxamine] results in increased expression of PMAIP1 mRNA; Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of PMAIP1 mRNA]
CTD PMID:33962019 NCBI chr18:59,986,187...59,990,174
Ensembl chr18:59,986,017...59,992,429
JBrowse link
G Pmp22 peripheral myelin protein 22 multiple interactions ISO [Deferoxamine results in decreased abundance of Iron] which results in decreased expression of PMP22 mRNA CTD PMID:12393473 NCBI chr10:47,795,709...47,825,715
Ensembl chr10:47,795,709...47,825,714
JBrowse link
G Ppia peptidylprolyl isomerase A multiple interactions
decreases expression
ISO ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of PPIA protein]
Deferoxamine results in decreased expression of PPIA protein
CTD PMID:19515424 NCBI chr14:81,279,292...81,282,960
Ensembl chr14:81,275,091...81,299,601
JBrowse link
G Prkcd protein kinase C, delta increases phosphorylation ISO Deferoxamine results in increased phosphorylation of PRKCD protein CTD PMID:17097691 NCBI chr16:5,769,226...5,807,214
Ensembl chr16:5,769,215...5,799,352
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases stability
increases expression
multiple interactions
ISO Deferoxamine results in increased stability of PTGS2 protein
Deferoxamine results in increased expression of PTGS2 mRNA; Deferoxamine results in increased expression of PTGS2 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Deferoxamine results in increased expression of PTGS2 protein]; [Sulindac co-treated with Deferoxamine] results in increased expression of PTGS2 protein; ferric citrate inhibits the reaction [Deferoxamine results in increased expression of PTGS2 protein]; Indomethacin promotes the reaction [Deferoxamine results in increased expression of PTGS2 protein]; TP53 gene mutant form promotes the reaction [Deferoxamine results in increased expression of PTGS2 protein]
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Deferoxamine results in increased expression of PTGS2 protein]; ferric citrate inhibits the reaction [Deferoxamine results in increased expression of PTGS2 protein]
CTD PMID:16527254 PMID:21882223 PMID:32816093 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Rack1 receptor for activated C kinase 1 decreases expression
multiple interactions
ISO Deferoxamine results in decreased expression of RACK1 protein
ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of RACK1 protein]
CTD PMID:19515424 NCBI chr10:33,169,415...33,174,896
Ensembl chr10:33,169,169...33,174,975
JBrowse link
G Ramp2 receptor activity modifying protein 2 decreases expression ISO Deferoxamine results in decreased expression of RAMP2 mRNA CTD PMID:11754965 NCBI chr10:86,187,366...86,190,692
Ensembl chr10:86,188,812...86,231,829
JBrowse link
G Rb1 RB transcriptional corepressor 1 decreases phosphorylation ISO Deferoxamine results in decreased phosphorylation of RB1 protein CTD PMID:11468187 NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302
JBrowse link
G Runx2 RUNX family transcription factor 2 decreases expression ISO Deferoxamine results in decreased expression of RUNX2 mRNA CTD PMID:16772336 NCBI chr 9:16,167,504...16,492,826
Ensembl chr 9:16,167,482...16,492,167
JBrowse link
G Sag S-antigen visual arrestin multiple interactions EXP Deferoxamine inhibits the reaction [SAG results in increased abundance of Free Radicals] CTD PMID:8407215 NCBI chr 9:88,467,797...88,508,821
Ensembl chr 9:88,469,376...88,508,820
JBrowse link
G Sdhb succinate dehydrogenase complex iron sulfur subunit B decreases expression ISO Deferoxamine results in decreased expression of SDHB protein CTD PMID:31238089 NCBI chr 5:153,264,906...153,285,570
Ensembl chr 5:153,264,899...153,314,293
JBrowse link
G Sele selectin E multiple interactions ISO [Deferoxamine affects the abundance of Iron] inhibits the reaction [TNF protein results in increased expression of SELE mRNA]; [Deferoxamine affects the abundance of Iron] inhibits the reaction [TNF protein results in increased expression of SELE protein] CTD PMID:12633744 NCBI chr13:76,402,841...76,412,741
Ensembl chr13:76,403,304...76,412,741
JBrowse link
G Sesn2 sestrin 2 multiple interactions ISO Deferoxamine inhibits the reaction [erastin results in increased expression of SESN2 protein] CTD PMID:31323261 NCBI chr 5:144,702,287...144,721,241
Ensembl chr 5:144,701,530...144,721,260
JBrowse link
G Setd1a SET domain containing 1A, histone lysine methyltransferase increases expression ISO Deferoxamine results in increased expression of SETD1A mRNA CTD PMID:23483119 NCBI chr 1:182,386,197...182,411,695
Ensembl chr 1:182,388,060...182,411,090
JBrowse link
G Setd2 SET domain containing 2, histone lysine methyltransferase increases expression
affects expression
ISO Deferoxamine results in increased expression of SETD2 mRNA
Deferoxamine affects the expression of SETD2 mRNA
CTD PMID:23483119 NCBI chr 8:110,511,808...110,597,489
Ensembl chr 8:110,511,772...110,597,489
JBrowse link
G Sirt1 sirtuin 1 increases expression ISO Deferoxamine results in increased expression of SIRT1 protein CTD PMID:22245592 NCBI chr20:25,307,143...25,329,260
Ensembl chr20:25,306,917...25,329,260
JBrowse link
G Slc11a2 solute carrier family 11 member 2 multiple interactions
decreases expression
increases expression
EXP
ISO
[Deferoxamine co-treated with Manganese] results in increased expression of SLC11A2; [Deferoxamine promotes the reaction [Doxorubicin results in increased expression of SLC11A2 protein]] which results in increased uptake of Copper; Deferoxamine promotes the reaction [Doxorubicin results in increased expression of SLC11A2 mRNA]; Deferoxamine promotes the reaction [Doxorubicin results in increased expression of SLC11A2 protein]
Deferoxamine results in decreased expression of SLC11A2 mRNA
Deferoxamine results in increased expression of SLC11A2 protein
[Deferoxamine results in decreased abundance of Iron] which results in increased expression of SLC11A2 mRNA; [Deferoxamine results in increased expression of SLC11A2 protein] which results in increased uptake of Manganese; Deferoxamine promotes the reaction [Deferoxamine results in increased expression of SLC11A2 protein]
CTD PMID:11933051 PMID:12393473 PMID:23764342 PMID:24089420 NCBI chr 7:131,503,076...131,540,246
Ensembl chr 7:131,503,081...131,540,145
JBrowse link
G Slc2a1 solute carrier family 2 member 1 multiple interactions
increases expression
ISO [Deferoxamine results in decreased abundance of Oxygen] which results in increased expression of SLC2A1 protein
Deferoxamine results in increased expression of SLC2A1 mRNA
CTD PMID:12032628 PMID:17442736 PMID:21558026 NCBI chr 5:132,717,196...132,745,416
Ensembl chr 5:132,717,196...132,745,416
JBrowse link
G Slc2a4 solute carrier family 2 member 4 decreases expression ISO Deferoxamine results in decreased expression of SLC2A4 mRNA CTD PMID:12032628 NCBI chr10:54,666,015...54,671,581
Ensembl chr10:54,666,015...54,671,565
JBrowse link
G Slc40a1 solute carrier family 40 member 1 increases expression
multiple interactions
ISO Deferoxamine results in increased expression of SLC40A1 protein
Deferoxamine inhibits the reaction [Busulfan results in decreased expression of SLC40A1 protein]
CTD PMID:31238089 PMID:32416107 NCBI chr 9:48,033,526...48,053,876
Ensembl chr 9:48,033,526...48,051,481
JBrowse link
G Slc6a2 solute carrier family 6 member 2 decreases expression EXP Deferoxamine results in decreased expression of SLC6A2 protein CTD PMID:16650837 NCBI chr19:14,010,292...14,055,317
Ensembl chr19:14,010,386...14,050,357
JBrowse link
G Slc7a11 solute carrier family 7 member 11 decreases expression ISO Deferoxamine results in decreased expression of SLC7A11 mRNA CTD PMID:32816093 NCBI chr 2:134,382,002...134,517,622
Ensembl chr 2:133,963,107...134,517,536
JBrowse link
G Slpi secretory leukocyte peptidase inhibitor decreases expression ISO Deferoxamine results in decreased expression of SLPI mRNA CTD PMID:32816093 NCBI chr 3:153,082,208...153,084,457
Ensembl chr 3:153,082,369...153,084,453
JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions
increases expression
ISO [Deferoxamine co-treated with SOD2 protein] results in increased expression of MMP1 mRNA; Deferoxamine inhibits the reaction [[Amitrole co-treated with SOD2 protein] results in increased expression of MMP1 mRNA]; Deferoxamine inhibits the reaction [[Buthionine Sulfoximine co-treated with SOD2 protein] results in increased expression of MMP1 mRNA]; TRAP1 protein inhibits the reaction [Deferoxamine results in increased expression of SOD2 protein]
Deferoxamine inhibits the reaction [SOD2 protein affects the reaction [Ethanol results in increased abundance of Iron]]
CTD PMID:10464329 PMID:16927372 PMID:19063909 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
JBrowse link
G Sp1 Sp1 transcription factor multiple interactions ISO [Deferoxamine affects the abundance of Iron] inhibits the reaction [TNF protein results in increased activity of SP1 protein] CTD PMID:12633744 NCBI chr 7:133,541,302...133,571,961
Ensembl chr 7:133,541,491...133,571,961
JBrowse link
G Sp7 Sp7 transcription factor multiple interactions ISO Deferoxamine inhibits the reaction [Ascorbic Acid results in increased expression of SP7 mRNA] CTD PMID:21467157 NCBI chr 7:133,484,609...133,494,788
Ensembl chr 7:133,484,609...133,494,847
JBrowse link
G Sqstm1 sequestosome 1 increases expression
multiple interactions
ISO Deferoxamine results in increased expression of SQSTM1 protein
[Copper co-treated with Deferoxamine] results in increased expression of SQSTM1 protein; [Iron co-treated with Deferoxamine] results in increased expression of SQSTM1 protein; Deferoxamine promotes the reaction [Palmitic Acid results in increased expression of SQSTM1 protein]
CTD PMID:25301941 PMID:32283200 NCBI chr10:34,525,517...34,536,685
Ensembl chr10:34,525,519...34,536,673
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 multiple interactions ISO [Paclitaxel co-treated with FV-429 compound co-treated with Deferoxamine] promotes the reaction [Oxygen deficiency results in increased expression of SREBF1 protein] CTD PMID:34648812 NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650
JBrowse link
G St6gal1 ST6 beta-galactoside alpha-2,6-sialyltransferase 1 multiple interactions ISO ST6GAL1 protein promotes the reaction [Deferoxamine results in increased expression of HIF1A protein] CTD PMID:29475939 NCBI chr11:77,526,837...77,653,474
Ensembl chr11:77,526,837...77,653,310
JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions EXP Deferoxamine inhibits the reaction [Copper Sulfate results in increased expression of STAT3 protein] CTD PMID:30431687 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
JBrowse link
G Suv39h1 SUV39H1 histone lysine methyltransferase decreases expression
increases expression
ISO Deferoxamine results in decreased expression of SUV39H1 mRNA
Deferoxamine results in increased expression of SUV39H1 mRNA
CTD PMID:23483119 NCBI chr  X:141,793,695...141,795,558 JBrowse link
G Tet2 tet methylcytosine dioxygenase 2 decreases expression ISO Deferoxamine results in decreased expression of TET2 protein CTD PMID:23483119 NCBI chr 2:221,988,645...222,072,813
Ensembl chr 2:221,988,645...222,072,534
JBrowse link
G Tf transferrin multiple interactions ISO Deferoxamine affects the reaction [TF protein affects the expression of ATP6V0D2 mRNA]; Deferoxamine inhibits the reaction [TF protein results in increased activity of ACP5 protein]; Deferoxamine inhibits the reaction [TF protein results in increased expression of CTSK mRNA]; Deferoxamine inhibits the reaction [TF protein results in increased expression of ITGB3 mRNA]; Deferoxamine inhibits the reaction [TF protein results in increased expression of MMP9 mRNA]; TF protein affects the reaction [Deferoxamine affects the expression of ATP6V0D2 mRNA]; TF protein affects the reaction [Deferoxamine results in decreased expression of CTSK mRNA]; TF protein affects the reaction [Deferoxamine results in increased expression of MMP9 mRNA]; TF protein inhibits the reaction [Deferoxamine results in decreased activity of ACP5 protein] CTD PMID:31238089 NCBI chr 8:103,789,780...103,816,487
Ensembl chr 8:103,767,995...103,816,511
JBrowse link
G Tfr2 transferrin receptor 2 decreases expression ISO Deferoxamine results in decreased expression of TFR2 protein CTD PMID:25633564 NCBI chr12:19,107,673...19,124,622
Ensembl chr12:19,107,673...19,124,591
JBrowse link
G Tfrc transferrin receptor increases expression
multiple interactions
ISO
EXP
Deferoxamine results in increased expression of TFRC mRNA; Deferoxamine results in increased expression of TFRC protein
Deferoxamine inhibits the reaction [Doxorubicin results in decreased expression of TFRC mRNA]
Deferoxamine affects the reaction [Magnetite Nanoparticles results in decreased expression of TFRC mRNA]; Deferoxamine promotes the reaction [Busulfan results in decreased expression of TFRC protein]
[Deferoxamine results in decreased abundance of Iron] which results in increased expression of TFRC mRNA; [Deferoxamine results in decreased abundance of Oxygen] which results in increased expression of TFRC protein
CTD PMID:11054110 PMID:12393473 PMID:12807743 PMID:15993339 PMID:16039939 More... NCBI chr11:68,163,413...68,185,257
Ensembl chr11:68,163,413...68,185,257
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions EXP Deferoxamine inhibits the reaction [Asbestos, Amosite results in increased expression of TGFB1 mRNA] CTD PMID:11306436 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Th tyrosine hydroxylase increases expression EXP Deferoxamine results in increased expression of TH mRNA CTD PMID:9458725 NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767
JBrowse link
G Tlr4 toll-like receptor 4 decreases expression ISO Deferoxamine results in decreased expression of TLR4 protein CTD PMID:24170104 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases response to substance
decreases expression
decreases activity
ISO
EXP
[Deferoxamine affects the abundance of Iron] inhibits the reaction [TNF protein results in increased activity of SP1 protein]; [Deferoxamine affects the abundance of Iron] inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]; [Deferoxamine affects the abundance of Iron] inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]; [Deferoxamine affects the abundance of Iron] inhibits the reaction [TNF protein results in increased expression of SELE mRNA]; [Deferoxamine affects the abundance of Iron] inhibits the reaction [TNF protein results in increased expression of SELE protein]; [Deferoxamine affects the abundance of Iron] inhibits the reaction [TNF protein results in increased expression of VCAM1 mRNA]; [Deferoxamine affects the abundance of Iron] inhibits the reaction [TNF protein results in increased expression of VCAM1 protein]; Deferoxamine inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; Deferoxamine inhibits the reaction [Particulate Matter results in increased expression of TNF mRNA]; ferrous sulfate inhibits the reaction [Deferoxamine results in decreased activity of TNF protein]
Deferoxamine inhibits the reaction [Asbestos, Crocidolite results in increased secretion of TNF protein]
Deferoxamine results in increased susceptibility to TNF protein
Deferoxamine inhibits the reaction [Asbestos, Crocidolite results in increased secretion of TNF protein]; Nitrites inhibits the reaction [[TNF protein results in increased activity of NOS2 protein] which results in increased chemical synthesis of Deferoxamine]
Deferoxamine results in decreased expression of TNF mRNA
CTD PMID:7532384 PMID:7539275 PMID:9851740 PMID:10486238 PMID:12633744 More... NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tnfaip6 TNF alpha induced protein 6 decreases expression ISO Deferoxamine results in decreased expression of TNFAIP6 mRNA CTD PMID:32816093 NCBI chr 3:36,502,250...36,521,652
Ensembl chr 3:36,502,188...36,521,649
JBrowse link
G Tnfrsf11a TNF receptor superfamily member 11A decreases expression ISO Deferoxamine results in decreased expression of TNFRSF11A mRNA CTD PMID:31238089 NCBI chr13:21,928,370...21,986,719
Ensembl chr13:21,928,408...21,986,695
JBrowse link
G Tnfsf11 TNF superfamily member 11 multiple interactions ISO [Deferoxamine co-treated with TNFSF11 protein] results in decreased phosphorylation of MAPK1 protein; [Deferoxamine co-treated with TNFSF11 protein] results in decreased phosphorylation of MAPK3 protein; Deferoxamine inhibits the reaction [[Hydrogen Peroxide co-treated with TNFSF11 protein] results in increased phosphorylation of MAPK1 protein]; Deferoxamine inhibits the reaction [[Hydrogen Peroxide co-treated with TNFSF11 protein] results in increased phosphorylation of MAPK3 protein] CTD PMID:31238089 NCBI chr15:53,674,990...53,705,171
Ensembl chr15:53,673,877...53,705,445
JBrowse link
G Tp53 tumor protein p53 multiple interactions
increases expression
decreases response to substance
ISO [Glucose co-treated with Deferoxamine] results in increased expression of TP53 mRNA; Deferoxamine inhibits the reaction [Asbestos, Amosite results in increased expression of TP53 mRNA]; Deferoxamine inhibits the reaction [sodium bichromate results in increased expression of TP53 protein]; Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of TP53 mRNA]; TP53 gene mutant form promotes the reaction [Deferoxamine results in increased expression of HIF1A protein]; TP53 gene mutant form promotes the reaction [Deferoxamine results in increased expression of PTGS2 protein]; TP53 protein affects the reaction [Deferoxamine results in increased expression of BAX protein]
Deferoxamine results in increased expression of TP53 protein
TP53 protein results in decreased susceptibility to Deferoxamine
CTD PMID:10942736 PMID:16357363 PMID:16527254 PMID:23483119 PMID:33962019 More... NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Tpd52l1 TPD52 like 1 decreases expression
multiple interactions
ISO Deferoxamine results in decreased expression of TPD52L1 protein
ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of TPD52L1 protein]
CTD PMID:19515424 NCBI chr 1:26,172,038...26,290,704
Ensembl chr 1:26,172,170...26,291,109
JBrowse link
G Tpi1 triosephosphate isomerase 1 increases expression EXP Deferoxamine results in increased expression of TPI1 mRNA CTD PMID:14762718 NCBI chr 4:157,615,283...157,618,813
Ensembl chr 4:157,615,386...157,619,541
JBrowse link
G Trap1 TNF receptor-associated protein 1 decreases expression
multiple interactions
ISO Deferoxamine results in decreased expression of TRAP1 mRNA; Deferoxamine results in decreased expression of TRAP1 protein
TRAP1 protein inhibits the reaction [Deferoxamine results in increased expression of SOD2 protein]
CTD PMID:16927372 NCBI chr10:11,464,882...11,498,931
Ensembl chr10:11,464,821...11,498,981
JBrowse link
G Tubb3 tubulin, beta 3 class III increases expression ISO Deferoxamine results in increased expression of TUBB3 mRNA CTD PMID:16772336 NCBI chr19:51,457,187...51,466,243
Ensembl chr19:51,457,184...51,466,243
JBrowse link
G Ucp2 uncoupling protein 2