S100a11 (S100 calcium binding protein A11) - Rat Genome Database

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Gene: S100a11 (S100 calcium binding protein A11) Rattus norvegicus
Analyze
Symbol: S100a11
Name: S100 calcium binding protein A11
RGD ID: 1303295
Description: Predicted to enable several functions, including S100 protein binding activity; calcium-dependent protein binding activity; and protein homodimerization activity. Predicted to be involved in positive regulation of smooth muscle cell migration. Predicted to be located in nucleus and ruffle. Predicted to be active in cytoplasm and extracellular space. Orthologous to human S100A11 (S100 calcium binding protein A11); INTERACTS WITH (+)-schisandrin B; 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: calgizzarin; LOC295195; protein S100-A11; S100 calcium binding protein A11 (calizzarin); S100 calcium-binding protein A11
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82181,875,132 - 181,880,542 (+)NCBIGRCr8
mRatBN7.22179,191,688 - 179,197,098 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2179,191,715 - 179,197,044 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2186,756,186 - 186,757,745 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02184,737,864 - 184,739,412 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02179,399,309 - 179,400,870 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02193,863,185 - 193,868,646 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2193,866,951 - 193,868,502 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02210,998,955 - 211,004,415 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42186,620,360 - 186,621,911 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12186,570,465 - 186,572,017 (+)NCBI
Celera2171,089,693 - 171,091,244 (-)NCBICelera
Cytogenetic Map2q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-catechin  (ISO)
(+)-schisandrin B  (EXP)
(1->4)-beta-D-glucan  (ISO)
1,1-dichloroethene  (ISO)
1,2-dimethylhydrazine  (ISO)
1-naphthyl isothiocyanate  (EXP)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3-dimethoxynaphthalene-1,4-dione  (ISO)
2,4,6-tribromophenol  (ISO)
2-acetamidofluorene  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
4,4'-diaminodiphenylmethane  (EXP,ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
5-aza-2'-deoxycytidine  (ISO)
5-fluorouracil  (ISO)
6-propyl-2-thiouracil  (EXP)
AACOCF3  (ISO)
acetamide  (EXP)
acetylsalicylic acid  (ISO)
acrylamide  (EXP)
aflatoxin B1  (EXP,ISO)
all-trans-retinoic acid  (ISO)
amphetamine  (EXP)
ampicillin  (EXP)
antirheumatic drug  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
ATP  (ISO)
azathioprine  (ISO)
benzo[a]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
bleomycin A2  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
carbamazepine  (ISO)
carbon nanotube  (ISO)
carnosic acid  (ISO)
carvedilol  (EXP)
CGP 52608  (ISO)
chlordecone  (ISO)
chloropicrin  (ISO)
choline  (ISO)
cisplatin  (ISO)
clopidogrel  (ISO)
cobalt dichloride  (EXP,ISO)
copper atom  (EXP)
copper(0)  (EXP)
copper(II) sulfate  (ISO)
crocidolite asbestos  (ISO)
Cuprizon  (EXP)
cyclosporin A  (ISO)
decabromodiphenyl ether  (ISO)
dexamethasone  (ISO)
dextran sulfate  (ISO)
diallyl trisulfide  (ISO)
diarsenic trioxide  (ISO)
Dibutyl phosphate  (ISO)
dopamine  (EXP)
dorsomorphin  (ISO)
doxorubicin  (ISO)
elemental selenium  (ISO)
enzyme inhibitor  (ISO)
epoxiconazole  (ISO)
fenoldopam  (EXP)
folic acid  (ISO)
folpet  (ISO)
FR900359  (ISO)
fructose  (EXP)
fumonisin B1  (ISO)
furan  (EXP)
gentamycin  (EXP)
glafenine  (EXP)
graphite  (ISO)
indole-3-methanol  (EXP)
isoprenaline  (EXP)
ivermectin  (ISO)
ketamine  (EXP)
L-methionine  (ISO)
lasalocid  (ISO)
lead diacetate  (ISO)
lead(II) chloride  (ISO)
leflunomide  (EXP)
lidocaine  (EXP)
lipopolysaccharide  (ISO)
mercury dibromide  (ISO)
methamphetamine  (EXP)
methotrexate  (ISO)
methylmercury chloride  (ISO)
metronidazole  (EXP)
microcystin-LR  (ISO)
Miglitol  (ISO)
mitomycin C  (ISO)
N-acetyl-L-cysteine  (ISO)
N-nitrosodiethylamine  (EXP,ISO)
N-nitrosodimethylamine  (EXP)
neomycin  (EXP)
nickel atom  (ISO)
O-methyleugenol  (ISO)
oxaliplatin  (ISO)
ozone  (ISO)
panobinostat  (ISO)
paracetamol  (EXP,ISO)
paraquat  (EXP)
PCB138  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenobarbital  (ISO)
phenylmercury acetate  (ISO)
pirinixic acid  (ISO)
potassium chromate  (ISO)
quercetin  (ISO)
rotenone  (EXP,ISO)
SB 431542  (ISO)
SCH 23390  (EXP)
selenium atom  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
sodium fluoride  (ISO)
temozolomide  (ISO)
testosterone  (ISO)
tetrachloromethane  (EXP,ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
trichloroethene  (ISO)
trichostatin A  (ISO)
triphenyl phosphate  (ISO)
Triptolide  (EXP)
tris(2-butoxyethyl) phosphate  (ISO)
trovafloxacin  (ISO)
tungsten  (ISO)
valproic acid  (ISO)
vancomycin  (EXP,ISO)
vinclozolin  (EXP)
vitamin E  (ISO)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IBA,ISO)
extracellular space  (IBA)
nucleus  (ISO)
ruffle  (ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. GOA pipeline RGD automated data pipeline
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10886724   PMID:10913138   PMID:14579419   PMID:16502470   PMID:19199708   PMID:21139050   PMID:23376485   PMID:23533145   PMID:23580065   PMID:25468996   PMID:27068509   PMID:31505169  
PMID:35419674  


Genomics

Comparative Map Data
S100a11
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82181,875,132 - 181,880,542 (+)NCBIGRCr8
mRatBN7.22179,191,688 - 179,197,098 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2179,191,715 - 179,197,044 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2186,756,186 - 186,757,745 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02184,737,864 - 184,739,412 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02179,399,309 - 179,400,870 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02193,863,185 - 193,868,646 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2193,866,951 - 193,868,502 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02210,998,955 - 211,004,415 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42186,620,360 - 186,621,911 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12186,570,465 - 186,572,017 (+)NCBI
Celera2171,089,693 - 171,091,244 (-)NCBICelera
Cytogenetic Map2q34NCBI
S100A11
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381152,032,506 - 152,037,004 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1152,032,506 - 152,047,907 (-)EnsemblGRCh38hg38GRCh38
GRCh371152,004,982 - 152,009,480 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361150,271,606 - 150,276,135 (-)NCBINCBI36Build 36hg18NCBI36
Build 341148,818,054 - 148,822,584NCBI
Celera1125,119,617 - 125,124,146 (-)NCBICelera
Cytogenetic Map1q21.3NCBI
HuRef1123,382,878 - 123,387,406 (-)NCBIHuRef
CHM1_11153,400,219 - 153,404,748 (-)NCBICHM1_1
T2T-CHM13v2.01151,156,052 - 151,160,549 (-)NCBIT2T-CHM13v2.0
S100a11
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39393,427,803 - 93,433,595 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl393,427,795 - 93,433,594 (+)EnsemblGRCm39 Ensembl
GRCm38393,520,496 - 93,526,288 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl393,520,488 - 93,526,287 (+)EnsemblGRCm38mm10GRCm38
MGSCv37393,324,418 - 93,330,210 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36394,218,196 - 94,224,175 (+)NCBIMGSCv36mm8
MGSCv36393,605,921 - 93,611,692 (+)NCBIMGSCv36mm8
Celera393,567,964 - 93,573,773 (-)NCBICelera
Cytogenetic Map3F2.1NCBI
cM Map340.51NCBI
S100a11
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955589408,319 - 413,971 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955589405,544 - 409,936 (+)NCBIChiLan1.0ChiLan1.0
S100A11
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2197,786,078 - 97,790,625 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1197,537,308 - 97,541,842 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01127,391,695 - 127,396,231 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11131,034,588 - 131,039,130 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1131,034,588 - 131,035,882 (-)Ensemblpanpan1.1panPan2
S100A11
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11761,020,136 - 61,050,513 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1760,463,767 - 60,494,558 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01762,039,324 - 62,045,008 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.11760,865,786 - 60,896,408 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01760,951,962 - 60,982,599 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01761,681,384 - 61,712,178 (-)NCBIUU_Cfam_GSD_1.0
S100A11
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl497,233,811 - 97,243,423 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1497,233,833 - 97,239,081 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24106,194,355 - 106,199,599 (+)NCBISscrofa10.2Sscrofa10.2susScr3
S100A11
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12011,613,171 - 11,617,711 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366603811,171,651 - 11,176,228 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
S100a11
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477219,563,889 - 19,568,766 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462477219,563,871 - 19,568,413 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in S100a11
49 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:61
Count of miRNA genes:50
Interacting mature miRNAs:52
Transcripts:ENSRNOT00000013393
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1358356Srcrt1Stress Responsive Cort QTL13.66blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)2161699179222436696Rat
1578648Bss11Bone structure and strength QTL 114.7femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)2114837527211674221Rat
1331734Bp204Blood pressure QTL 2043.61192arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2168358098223265385Rat
1298074Bp164Blood pressure QTL 1640.003arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)242804607202447032Rat
1354648Bp239Blood pressure QTL 2390.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)266118463226797303Rat
1354649Kidm17Kidney mass QTL 172.9kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)281754530227146641Rat
1298076Bp166Blood pressure QTL 1660.0009arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2136445150202447032Rat
70162Bp63Blood pressure QTL 635.64arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)2169745596214745596Rat
1554319Bmd2Bone mineral density QTL 213.40.0001lumbar vertebra area (VT:0010570)lumbar vertebra cross-sectional area (CMO:0001689)2114837675212549332Rat
12879836Kidm61Kidney mass QTL 610.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)2152413072185122374Rat
1581569Uae32Urinary albumin excretion QTL 320.0001urine protein amount (VT:0005160)urine albumin excretion rate (CMO:0000757)278665619219826953Rat
10043136Iddm54Insulin dependent diabetes mellitus QTL 543.40.0001blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)2143657411190602963Rat
12879837Am2Aortic mass QTL 20.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)2152413072185122374Rat
1302793Bw16Body weight QTL 1650.0001body mass (VT:0001259)body weight (CMO:0000012)2157142209202446871Rat
12879838Cm86Cardiac mass QTL 860.002heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)2152413072185122374Rat
61467Bp14Blood pressure QTL 142.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)243154682202446871Rat
12879839Cm85Cardiac mass QTL 850.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)2152413072185122374Rat
61469Bp16Blood pressure QTL 165.64arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)2169745596214745596Rat
70175BpQTLCluster3Blood pressure QTL cluster 34.128arterial blood pressure trait (VT:2000000)absolute change in systolic blood pressure (CMO:0000607)2135552573202446871Rat
1549833Bp257Blood pressure QTL 2570.003arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2168354880185122374Rat
1358900Bw48Body weight QTL 484.88body mass (VT:0001259)body weight (CMO:0000012)2157142078211086598Rat
1359030Bp277Blood pressure QTL 277arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)2114837527185876470Rat
1331760Bp206Blood pressure QTL 2063.62454arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)256043031202447032Rat
12879840Bw179Body weight QTL 1790.005body mass (VT:0001259)body weight (CMO:0000012)2152413072185122374Rat
1581502Esta3Estrogen-induced thymic atrophy QTL 3thymus mass (VT:0004954)thymus wet weight (CMO:0000855)2136916935189599348Rat
1359032Hrtrt18Heart rate QTL 18heart pumping trait (VT:2000009)heart rate (CMO:0000002)2157142078192625452Rat
2301966Bp322Blood pressure QTL 3223.58arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2150540301202447032Rat
1298080Bp163Blood pressure QTL 1630.02arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)266118275202447032Rat
8662832Vetf7Vascular elastic tissue fragility QTL 73.5aorta elastin amount (VT:0003905)aorta wall extracellular elastin dry weight to aorta wall dry weight ratio (CMO:0002002)281689826221035911Rat
1298085Bp165Blood pressure QTL 1650.0006arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)242804607202447032Rat
1641891Alcrsp17Alcohol response QTL 17response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)2149559561249053267Rat
1359022Ppulsi1Prepulse inhibition QTL 13.63prepulse inhibition trait (VT:0003088)acoustic startle response measurement (CMO:0001519)2136916935213594495Rat
724534Uae6Urinary albumin excretion QTL 610urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)278665619249053267Rat
61374Edpm2Estrogen-dependent pituitary mass QTL 24.420.86pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)276539322202447032Rat
8662843Vetf9Vascular elastic tissue fragility QTL 92.05thoracic aorta molecular composition trait (VT:0010568)aorta wall extracellular elastin dry weight to aorta wall extracellular collagen weight ratio (CMO:0002003)2157142078226277316Rat
631501Bp101Blood pressure QTL 1012.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2150341684202446871Rat
2307174Activ3Activity QTL 34.830.000058locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)2168594495213594495Rat
1331794Bp202Blood pressure QTL 2023.66819arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2141194931223265385Rat
71113Cari2Carrageenan-induced inflammation QTL 22.70.009hypodermis integrity trait (VT:0010550)inflammatory exudate volume (CMO:0001429)2141596551202447032Rat
1331805Cm29Cardiac mass QTL 293.50746heart mass (VT:0007028)heart wet weight (CMO:0000069)2141194931223265385Rat
1598805Memor8Memory QTL 83exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)2150341585189039377Rat
634308Sach6Saccharin preference QTL 64.9taste sensitivity trait (VT:0001986)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)2112456140212696837Rat
1358917Cm42Cardiac mass QTL 422.82heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423203928301Rat
724568Uae13Urinary albumin excretion QTL 134.4urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)2143157029210020885Rat
1358913Cm41Cardiac mass QTL 412.73heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423203928301Rat
1300165Rf9Renal function QTL 93.28kidney glomerulus integrity trait (VT:0010546)index of glomerular damage (CMO:0001135)2133914684202447032Rat
61401Niddm2Non-insulin dependent diabetes mellitus QTL 24.54blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)2144599348189599348Rat
631507Bp105Blood pressure QTL 1050.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2112456140212696837Rat
1641925Alcrsp2Alcohol response QTL 2response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)2149559561221167075Rat
1354609Niddm62Non-insulin dependent diabetes mellitus QTL 624.720.000006insulin secretion trait (VT:0003564)plasma insulin level (CMO:0000342)2150540301202447032Rat
1598833Bp295Blood pressure QTL 2953.5arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2147798556192798556Rat
1354622Kidm16Kidney mass QTL 163kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)281754530222436696Rat
631266Bp132Blood pressure QTL 1320.0005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)246123260202447032Rat
631522Bp74Blood pressure QTL 740.05arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2172710921184114403Rat
7488927Bp365Blood pressure QTL 3650.008arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2162765032207765032Rat
1598838Bp290Blood pressure QTL 2901.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2166539266211539266Rat
7488925Bp364Blood pressure QTL 3640.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2160564068205564068Rat
2293843Kiddil6Kidney dilation QTL 63.1kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)242804607182042367Rat
2306901Bp337Blood pressure QTL 3370.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2164073756227146641Rat
1354605Rf48Renal function QTL 482.9blood creatinine amount (VT:0005328)plasma creatinine level (CMO:0000537)274786664206665859Rat
6903312Bw112Body weight QTL 1123.20.0013body mass (VT:0001259)body weight (CMO:0000012)2143657569184114274Rat
1354601Slep1Serum leptin concentration QTL 15.39blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)243171017184114403Rat
2293084Iddm26Insulin dependent diabetes mellitus QTL 262.9blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)2174930955213594495Rat

Markers in Region
RH142335  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21365,756,714 - 65,756,864 (+)MAPPERmRatBN7.2
mRatBN7.22179,195,449 - 179,196,854 (+)MAPPERmRatBN7.2
Rnor_6.02193,866,998 - 193,868,402NCBIRnor6.0
Rnor_6.01371,039,887 - 71,040,036NCBIRnor6.0
Rnor_5.01376,004,788 - 76,004,937UniSTSRnor5.0
Rnor_5.02210,999,199 - 211,000,603UniSTSRnor5.0
RGSC_v3.42186,620,407 - 186,621,811UniSTSRGSC3.4
RGSC_v3.41368,627,263 - 68,627,412UniSTSRGSC3.4
Celera1365,659,608 - 65,659,757UniSTS
Celera2171,089,793 - 171,091,197UniSTS
Cytogenetic Map2q34UniSTS
S100a11  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22179,195,417 - 179,196,879 (+)MAPPERmRatBN7.2
mRatBN7.217488,891 - 489,098 (-)MAPPERmRatBN7.2
Rnor_6.0172,165,936 - 2,166,142NCBIRnor6.0
Rnor_6.02193,866,966 - 193,868,427NCBIRnor6.0
Rnor_5.0172,152,377 - 2,152,583UniSTSRnor5.0
Rnor_5.02210,999,174 - 211,000,635UniSTSRnor5.0
RGSC_v3.42186,620,375 - 186,621,836UniSTSRGSC3.4
RGSC_v3.4175,971,124 - 5,971,330UniSTSRGSC3.4
Celera172,023,591 - 2,023,797UniSTS
Celera2171,089,768 - 171,091,229UniSTS
Cytogenetic Map17p14UniSTS
Cytogenetic Map2q34UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High 15
Medium 21 132 185 111 69 111 18 25 192 115 109 42 6
Low 9 42 36 36 18 20 58 36 18
Below cutoff

Sequence


Ensembl Acc Id: ENSRNOT00000013393   ⟹   ENSRNOP00000013393
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2179,191,715 - 179,197,044 (+)Ensembl
Rnor_6.0 Ensembl2193,866,951 - 193,868,502 (+)Ensembl
RefSeq Acc Id: NM_001004095   ⟹   NP_001004095
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82181,875,132 - 181,880,542 (+)NCBI
mRatBN7.22179,191,688 - 179,197,098 (+)NCBI
Rnor_6.02193,866,951 - 193,868,502 (+)NCBI
Rnor_5.02210,998,955 - 211,004,415 (-)NCBI
RGSC_v3.42186,620,360 - 186,621,911 (+)RGD
Celera2171,089,693 - 171,091,244 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001004095 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAT91807 (Get FASTA)   NCBI Sequence Viewer  
  EDL87853 (Get FASTA)   NCBI Sequence Viewer  
  EDL87855 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000013393.4
  ENSRNOP00055045242
  ENSRNOP00060017179
  ENSRNOP00065032759
GenBank Protein Q6B345 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001004095   ⟸   NM_001004095
- UniProtKB: Q6B345 (UniProtKB/Swiss-Prot),   A6KMM4 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000013393   ⟸   ENSRNOT00000013393
Protein Domains
EF-hand

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q6B345-F1-model_v2 AlphaFold Q6B345 1-98 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13691519
Promoter ID:EPDNEW_R2043
Type:multiple initiation site
Name:S100a11_1
Description:S100 calcium binding protein A11
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.02193,866,947 - 193,867,007EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1303295 AgrOrtholog
BioCyc Gene G2FUF-52233 BioCyc
Ensembl Genes ENSRNOG00000010105 Ensembl, UniProtKB/Swiss-Prot
  ENSRNOG00055031612 UniProtKB/Swiss-Prot
  ENSRNOG00060012775 UniProtKB/Swiss-Prot
  ENSRNOG00065023539 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000013393.7 UniProtKB/Swiss-Prot
  ENSRNOT00055054735 UniProtKB/Swiss-Prot
  ENSRNOT00060021712 UniProtKB/Swiss-Prot
  ENSRNOT00065040256 UniProtKB/Swiss-Prot
Gene3D-CATH EF-hand UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro EF-hand-dom_pair UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EF_Hand_1_Ca_BS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EF_hand_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  S100/CaBP-9k_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  S100_Ca-bd_sub UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  S100A11 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:445415 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 445415 ENTREZGENE
PANTHER PROTEIN S100-A11 UniProtKB/TrEMBL, UniProtKB/Swiss-Prot
  S100 CALCIUM-BINDING PROTEIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam EF-hand_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  S_100 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen S100a11 PhenoGen
PROSITE EF_HAND_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EF_HAND_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  S100_CABP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000010105 RatGTEx
  ENSRNOG00055031612 RatGTEx
  ENSRNOG00060012775 RatGTEx
  ENSRNOG00065023539 RatGTEx
SMART EFh UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  S_100 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP EF-hand UniProtKB/TrEMBL, UniProtKB/Swiss-Prot
UniProt A6KMM4 ENTREZGENE, UniProtKB/TrEMBL
  Q6B345 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-01-17 S100a11  S100 calcium binding protein A11  S100a11  S100 calcium binding protein A11 (calizzarin)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-04-06 S100a11  S100 calcium binding protein A11 (calizzarin)  S100a11_predicted  S100 calcium binding protein A11 (calizzarin) (predicted)  Data merged from RGD:1311895 737654 APPROVED
2005-09-30 S100a11        Symbol and Name status set to provisional 70820 PROVISIONAL
2005-01-12 S100a11_predicted  S100 calcium binding protein A11 (calizzarin) (predicted)      Symbol and Name status set to approved 70820 APPROVED