Pdha1 Rat (+)-catechin multiple interactions ISO PDHA1 (Homo sapiens) 6480464 [Catechin co-treated with Grape Seed Proanthocyanidins] results in increased expression of PDHA1 mRNA CTD PMID:24763279 Pdha1 Rat (-)-epigallocatechin 3-gallate multiple interactions ISO PDHA1 (Homo sapiens) 6480464 Acetylcysteine inhibits the reaction [epigallocatechin gallate results in decreased expression of PDHA1 mRNA] and Acetylcysteine inhibits the reaction [epigallocatechin gallate results in decreased expression of PDHA1 protein] CTD PMID:31857147 Pdha1 Rat (-)-epigallocatechin 3-gallate decreases expression ISO PDHA1 (Homo sapiens) 6480464 epigallocatechin gallate results in decreased expression of PDHA1 mRNA and epigallocatechin gallate results in decreased expression of PDHA1 protein CTD PMID:31857147 Pdha1 Rat 1,2-dimethylhydrazine multiple interactions ISO Pdha1 (Mus musculus) 6480464 [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of PDHA1 mRNA CTD PMID:22206623 Pdha1 Rat 17alpha-ethynylestradiol multiple interactions ISO Pdha1 (Mus musculus) 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of PDHA1 mRNA CTD PMID:17942748 Pdha1 Rat 17beta-estradiol multiple interactions EXP 6480464 [bisphenol A co-treated with Estradiol] results in decreased expression of PDHA1 mRNA CTD PMID:26496021 Pdha1 Rat 2,3,7,8-tetrabromodibenzodioxine affects expression ISO Pdha1 (Mus musculus) 6480464 2 more ... CTD PMID:27604104 Pdha1 Rat 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO Pdha1 (Mus musculus) 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of PDHA1 mRNA CTD PMID:17942748 Pdha1 Rat 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of PDHA1 mRNA CTD PMID:34747641 Pdha1 Rat 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of PDHA1 mRNA CTD PMID:32109520 Pdha1 Rat 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO Pdha1 (Mus musculus) 6480464 Tetrachlorodibenzodioxin affects the expression of PDHA1 mRNA CTD PMID:21570461 Pdha1 Rat 2,3,7,8-Tetrachlorodibenzofuran decreases expression EXP 6480464 2 more ... CTD PMID:32109520 Pdha1 Rat 3-chloropropane-1,2-diol increases expression EXP 6480464 alpha-Chlorohydrin results in increased expression of PDHA1 mRNA and alpha-Chlorohydrin results in increased expression of PDHA1 protein CTD PMID:26072098 and PMID:28522335 Pdha1 Rat 4,4'-diaminodiphenylmethane increases expression ISO Pdha1 (Mus musculus) 6480464 4 and 4'-diaminodiphenylmethane results in increased expression of PDHA1 mRNA CTD PMID:18648102 Pdha1 Rat aflatoxin B1 increases methylation ISO PDHA1 (Homo sapiens) 6480464 Aflatoxin B1 results in increased methylation of PDHA1 intron CTD PMID:30157460 Pdha1 Rat aldehydo-D-glucose multiple interactions ISO PDHA1 (Homo sapiens) 6480464 Glucose inhibits the reaction [Dichloroacetic Acid results in decreased phosphorylation of PDHA1 protein] CTD PMID:31654802 Pdha1 Rat all-trans-retinoic acid decreases expression ISO PDHA1 (Homo sapiens) 6480464 Tretinoin results in decreased expression of PDHA1 mRNA CTD PMID:21934132 Pdha1 Rat alpha-Zearalanol multiple interactions EXP 6480464 [Zeranol co-treated with perfluorooctanoic acid] results in increased expression of PDHA1 mRNA CTD PMID:35163327 Pdha1 Rat ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of PDHA1 mRNA CTD PMID:16483693 Pdha1 Rat angiotensin II multiple interactions EXP 6480464 celastrol methyl ester inhibits the reaction [Angiotensin II results in decreased expression of PDHA1 mRNA] and PPARA protein promotes the reaction [celastrol methyl ester inhibits the reaction [Angiotensin II results in decreased expression of PDHA1 mRNA]] CTD PMID:37269933 Pdha1 Rat angiotensin II decreases expression EXP 6480464 Angiotensin II results in decreased expression of PDHA1 mRNA CTD PMID:37269933 Pdha1 Rat Aroclor 1254 decreases expression ISO Pdha1 (Mus musculus) 6480464 Chlorodiphenyl (54% Chlorine) results in decreased expression of PDHA1 mRNA CTD PMID:23650126 Pdha1 Rat arsenite(3-) multiple interactions ISO PDHA1 (Homo sapiens) 6480464 arsenite inhibits the reaction [G3BP1 protein binds to PDHA1 protein] and arsenite promotes the reaction [G3BP1 protein binds to PDHA1 mRNA] CTD PMID:32406909 Pdha1 Rat arsenous acid increases expression ISO PDHA1 (Homo sapiens) 6480464 Arsenic Trioxide results in increased expression of PDHA1 mRNA CTD PMID:22521957 Pdha1 Rat atrazine decreases expression ISO PDHA1 (Homo sapiens) 6480464 Atrazine results in decreased expression of PDHA1 mRNA CTD PMID:22378314 Pdha1 Rat benzo[a]pyrene multiple interactions ISO Pdha1 (Mus musculus) 6480464 Benzo(a)pyrene promotes the reaction [AHR protein binds to PDHA1 promoter] CTD PMID:19654925 Pdha1 Rat benzo[a]pyrene affects methylation ISO PDHA1 (Homo sapiens) 6480464 Benzo(a)pyrene affects the methylation of PDHA1 5' UTR and Benzo(a)pyrene affects the methylation of PDHA1 promoter CTD PMID:27901495 Pdha1 Rat benzo[a]pyrene decreases expression ISO Pdha1 (Mus musculus) 6480464 Benzo(a)pyrene results in decreased expression of PDHA1 mRNA CTD PMID:22228805 Pdha1 Rat bezafibrate increases expression EXP 6480464 Bezafibrate results in increased expression of PDHA1 mRNA CTD PMID:11527545 Pdha1 Rat bis(2-ethylhexyl) phthalate increases expression ISO Pdha1 (Mus musculus) 6480464 Diethylhexyl Phthalate results in increased expression of PDHA1 mRNA CTD PMID:35550907 Pdha1 Rat bisphenol A increases expression ISO Pdha1 (Mus musculus) 6480464 bisphenol A results in increased expression of PDHA1 mRNA CTD PMID:22687993 Pdha1 Rat bisphenol A multiple interactions ISO PDHA1 (Homo sapiens) 6480464 [bisphenol A co-treated with Fulvestrant] results in decreased methylation of PDHA1 gene CTD PMID:31601247 Pdha1 Rat bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of PDHA1 mRNA CTD PMID:34947998 Pdha1 Rat bisphenol A decreases expression ISO PDHA1 (Homo sapiens) 6480464 bisphenol A results in decreased expression of PDHA1 mRNA CTD PMID:29275510 Pdha1 Rat bisphenol A increases methylation EXP 6480464 bisphenol A results in increased methylation of PDHA1 gene CTD PMID:28505145 Pdha1 Rat bisphenol A increases methylation ISO Pdha1 (Mus musculus) 6480464 bisphenol A results in increased methylation of PDHA1 promoter CTD PMID:27312807 Pdha1 Rat bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of PDHA1 mRNA CTD PMID:25181051 Pdha1 Rat bisphenol A multiple interactions EXP 6480464 [bisphenol A co-treated with Estradiol] results in decreased expression of PDHA1 mRNA CTD PMID:26496021 Pdha1 Rat bisphenol A decreases expression ISO Pdha1 (Mus musculus) 6480464 bisphenol A results in decreased expression of PDHA1 mRNA CTD PMID:22687993 Pdha1 Rat Bisphenol B increases expression ISO PDHA1 (Homo sapiens) 6480464 bisphenol B results in increased expression of PDHA1 protein CTD PMID:34186270 Pdha1 Rat bisphenol F increases expression ISO PDHA1 (Homo sapiens) 6480464 bisphenol F results in increased expression of PDHA1 protein CTD PMID:34186270 Pdha1 Rat cadmium atom decreases expression ISO PDHA1 (Homo sapiens) 6480464 Cadmium results in decreased expression of PDHA1 mRNA CTD PMID:23369406 Pdha1 Rat cadmium dichloride decreases expression ISO PDHA1 (Homo sapiens) 6480464 Cadmium Chloride results in decreased expression of PDHA1 mRNA CTD PMID:38568856 Pdha1 Rat celastrol multiple interactions ISO Pdha1 (Mus musculus) 6480464 celastrol inhibits the reaction [Dietary Fats results in increased phosphorylation of PDHA1 protein] CTD PMID:35679966 Pdha1 Rat celastrol decreases phosphorylation ISO Pdha1 (Mus musculus) 6480464 celastrol results in decreased phosphorylation of PDHA1 protein CTD PMID:35679966 Pdha1 Rat ciguatoxin CTX1B affects expression ISO Pdha1 (Mus musculus) 6480464 Ciguatoxins affects the expression of PDHA1 mRNA CTD PMID:18353800 Pdha1 Rat cobalt dichloride decreases expression ISO PDHA1 (Homo sapiens) 6480464 cobaltous chloride results in decreased expression of PDHA1 mRNA CTD PMID:19376846 Pdha1 Rat D-glucose multiple interactions ISO PDHA1 (Homo sapiens) 6480464 Glucose inhibits the reaction [Dichloroacetic Acid results in decreased phosphorylation of PDHA1 protein] CTD PMID:31654802 Pdha1 Rat dexamethasone increases expression ISO PDHA1 (Homo sapiens) 6480464 Dexamethasone results in increased expression of PDHA1 mRNA CTD PMID:25047013 Pdha1 Rat diarsenic trioxide increases expression ISO PDHA1 (Homo sapiens) 6480464 Arsenic Trioxide results in increased expression of PDHA1 mRNA CTD PMID:22521957 Pdha1 Rat Dibutyl phosphate affects expression ISO PDHA1 (Homo sapiens) 6480464 di-n-butylphosphoric acid affects the expression of PDHA1 mRNA CTD PMID:37042841 Pdha1 Rat dichloroacetic acid decreases phosphorylation ISO PDHA1 (Homo sapiens) 6480464 Dichloroacetic Acid results in decreased phosphorylation of PDHA1 protein CTD PMID:25630799 and PMID:31654802 Pdha1 Rat dichloroacetic acid multiple interactions ISO PDHA1 (Homo sapiens) 6480464 Glucose inhibits the reaction [Dichloroacetic Acid results in decreased phosphorylation of PDHA1 protein] CTD PMID:31654802 Pdha1 Rat dinophysistoxin 1 affects expression ISO PDHA1 (Homo sapiens) 6480464 dinophysistoxin 1 affects the expression of PDHA1 mRNA CTD PMID:28939011 Pdha1 Rat diuron decreases expression EXP 6480464 Diuron results in decreased expression of PDHA1 mRNA CTD PMID:21551480 Pdha1 Rat dorsomorphin multiple interactions ISO Pdha1 (Mus musculus) 6480464 dorsomorphin inhibits the reaction [Resveratrol results in increased expression of PDHA1 protein] CTD PMID:25761413 Pdha1 Rat doxorubicin increases phosphorylation ISO Pdha1 (Mus musculus) 6480464 Doxorubicin results in increased phosphorylation of PDHA1 mRNA CTD PMID:29653124 Pdha1 Rat doxorubicin decreases expression ISO PDHA1 (Homo sapiens) 6480464 Doxorubicin results in decreased expression of PDHA1 mRNA CTD PMID:29803840 Pdha1 Rat duvoglustat multiple interactions ISO Pdha1 (Mus musculus) 6480464 [1-Deoxynojirimycin co-treated with Polysaccharides] results in increased expression of PDHA1 mRNA CTD PMID:25446853 Pdha1 Rat epoxiconazole decreases expression ISO Pdha1 (Mus musculus) 6480464 epoxiconazole results in decreased expression of PDHA1 mRNA CTD PMID:35436446 Pdha1 Rat ethanol increases expression ISO Pdha1 (Mus musculus) 6480464 Ethanol results in increased expression of PDHA1 mRNA CTD PMID:19167417 Pdha1 Rat ethanol increases expression EXP 6480464 Ethanol results in increased expression of PDHA1 protein CTD PMID:19609968 and PMID:23702218 Pdha1 Rat flutamide increases expression EXP 6480464 Flutamide results in increased expression of PDHA1 mRNA CTD PMID:24136188 Pdha1 Rat folic acid decreases expression ISO Pdha1 (Mus musculus) 6480464 Folic Acid results in decreased expression of PDHA1 mRNA CTD PMID:25629700 Pdha1 Rat folic acid multiple interactions ISO Pdha1 (Mus musculus) 6480464 [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of PDHA1 mRNA CTD PMID:22206623 Pdha1 Rat formaldehyde decreases expression ISO PDHA1 (Homo sapiens) 6480464 Formaldehyde results in decreased expression of PDHA1 mRNA CTD PMID:23649840 Pdha1 Rat FR900359 increases phosphorylation ISO PDHA1 (Homo sapiens) 6480464 FR900359 results in increased phosphorylation of PDHA1 protein CTD PMID:37730182 Pdha1 Rat fulvestrant multiple interactions ISO PDHA1 (Homo sapiens) 6480464 [bisphenol A co-treated with Fulvestrant] results in decreased methylation of PDHA1 gene CTD PMID:31601247 Pdha1 Rat Fusaric acid increases phosphorylation ISO PDHA1 (Homo sapiens) 6480464 Fusaric Acid results in increased phosphorylation of PDHA1 protein CTD PMID:31654802 Pdha1 Rat Fusaric acid decreases phosphorylation ISO Pdha1 (Mus musculus) 6480464 Fusaric Acid results in decreased phosphorylation of PDHA1 protein CTD PMID:32156565 Pdha1 Rat genistein increases methylation EXP 6480464 Genistein results in increased methylation of PDHA1 gene CTD PMID:28505145 Pdha1 Rat gentamycin increases expression EXP 6480464 Gentamicins results in increased expression of PDHA1 mRNA CTD PMID:22061828 Pdha1 Rat glucose multiple interactions ISO PDHA1 (Homo sapiens) 6480464 Glucose inhibits the reaction [Dichloroacetic Acid results in decreased phosphorylation of PDHA1 protein] CTD PMID:31654802 Pdha1 Rat hydrogen peroxide multiple interactions ISO Pdha1 (Mus musculus) 6480464 [Hydrogen Peroxide co-treated with N-(oxo-5 more ... CTD PMID:31494107 Pdha1 Rat Ile(5)-angiotensin II decreases expression EXP 6480464 Angiotensin II results in decreased expression of PDHA1 mRNA CTD PMID:37269933 Pdha1 Rat Ile(5)-angiotensin II multiple interactions EXP 6480464 celastrol methyl ester inhibits the reaction [Angiotensin II results in decreased expression of PDHA1 mRNA] and PPARA protein promotes the reaction [celastrol methyl ester inhibits the reaction [Angiotensin II results in decreased expression of PDHA1 mRNA]] CTD PMID:37269933 Pdha1 Rat isotretinoin decreases expression ISO PDHA1 (Homo sapiens) 6480464 Isotretinoin results in decreased expression of PDHA1 mRNA CTD PMID:20436886 Pdha1 Rat ivermectin decreases expression ISO PDHA1 (Homo sapiens) 6480464 Ivermectin results in decreased expression of PDHA1 protein CTD PMID:32959892 Pdha1 Rat kojic acid increases expression ISO PDHA1 (Homo sapiens) 6480464 kojic acid results in increased expression of PDHA1 mRNA CTD PMID:16595896 Pdha1 Rat maneb multiple interactions ISO Pdha1 (Mus musculus) 6480464 [Maneb co-treated with Paraquat] results in decreased expression of PDHA1 mRNA more ... CTD PMID:23562983 and PMID:23963992 Pdha1 Rat metformin multiple interactions ISO PDHA1 (Homo sapiens) 6480464 Metformin results in decreased phosphorylation of and results in increased activity of PDHA1 protein CTD PMID:28576465 Pdha1 Rat methamphetamine decreases expression EXP 6480464 Methamphetamine results in decreased expression of PDHA1 protein CTD PMID:19826936 Pdha1 Rat methyl methanesulfonate decreases expression ISO PDHA1 (Homo sapiens) 6480464 Methyl Methanesulfonate results in decreased expression of PDHA1 mRNA CTD PMID:23649840 Pdha1 Rat Methylazoxymethanol acetate increases expression EXP 6480464 Methylazoxymethanol Acetate results in increased expression of PDHA1 mRNA CTD PMID:28349193 Pdha1 Rat methylmercury chloride decreases expression ISO PDHA1 (Homo sapiens) 6480464 methylmercuric chloride results in decreased expression of PDHA1 mRNA CTD PMID:28001369 Pdha1 Rat methylparaben increases expression ISO PDHA1 (Homo sapiens) 6480464 methylparaben results in increased expression of PDHA1 mRNA CTD PMID:31745603 Pdha1 Rat mitoxantrone decreases expression ISO Pdha1 (Mus musculus) 6480464 Mitoxantrone results in decreased expression of PDHA1 protein CTD PMID:34246718 Pdha1 Rat N-acetyl-L-cysteine multiple interactions ISO PDHA1 (Homo sapiens) 6480464 Acetylcysteine inhibits the reaction [epigallocatechin gallate results in decreased expression of PDHA1 mRNA] and Acetylcysteine inhibits the reaction [epigallocatechin gallate results in decreased expression of PDHA1 protein] CTD PMID:31857147 Pdha1 Rat nefazodone increases expression EXP 6480464 nefazodone results in increased expression of PDHA1 mRNA CTD PMID:24136188 Pdha1 Rat okadaic acid increases expression ISO PDHA1 (Homo sapiens) 6480464 Okadaic Acid results in increased expression of PDHA1 mRNA CTD PMID:28939011 Pdha1 Rat ozone multiple interactions ISO PDHA1 (Homo sapiens) 6480464 [Air Pollutants results in increased abundance of Ozone] which affects the expression of PDHA1 mRNA CTD PMID:35430440 Pdha1 Rat paracetamol decreases expression ISO PDHA1 (Homo sapiens) 6480464 Acetaminophen results in decreased expression of PDHA1 mRNA CTD PMID:25704631 Pdha1 Rat paraquat multiple interactions ISO Pdha1 (Mus musculus) 6480464 [Maneb co-treated with Paraquat] results in decreased expression of PDHA1 mRNA more ... CTD PMID:23562983 and PMID:23963992 Pdha1 Rat PCB138 increases expression EXP 6480464 2 more ... CTD PMID:21673325 Pdha1 Rat perfluorooctanoic acid multiple interactions ISO Pdha1 (Mus musculus) 6480464 Dietary Fats and Unsaturated inhibits the reaction [perfluorooctanoic acid results in increased expression of PDHA1 mRNA] CTD PMID:23626681 Pdha1 Rat perfluorooctanoic acid increases expression ISO PDHA1 (Homo sapiens) 6480464 perfluorooctanoic acid results in increased expression of PDHA1 protein CTD PMID:26879310 Pdha1 Rat perfluorooctanoic acid multiple interactions EXP 6480464 [Zeranol co-treated with perfluorooctanoic acid] results in increased expression of PDHA1 mRNA CTD PMID:35163327 Pdha1 Rat picoxystrobin increases expression ISO PDHA1 (Homo sapiens) 6480464 picoxystrobin results in increased expression of PDHA1 mRNA CTD PMID:33512557 Pdha1 Rat pirinixic acid increases expression EXP 6480464 pirinixic acid results in increased expression of PDHA1 mRNA CTD PMID:11527545 and PMID:19162173 Pdha1 Rat pirinixic acid increases expression ISO Pdha1 (Mus musculus) 6480464 pirinixic acid results in increased expression of PDHA1 mRNA CTD PMID:23811191 Pdha1 Rat pregnenolone 16alpha-carbonitrile increases expression ISO Pdha1 (Mus musculus) 6480464 Pregnenolone Carbonitrile results in increased expression of PDHA1 mRNA CTD PMID:28903501 Pdha1 Rat quinoline increases expression ISO PDHA1 (Homo sapiens) 6480464 quinoline analog results in increased expression of PDHA1 protein CTD PMID:18645022 Pdha1 Rat resveratrol decreases expression ISO PDHA1 (Homo sapiens) 6480464 resveratrol results in decreased expression of PDHA1 mRNA CTD PMID:15582268 Pdha1 Rat resveratrol increases expression ISO Pdha1 (Mus musculus) 6480464 resveratrol results in increased expression of PDHA1 protein CTD PMID:25505154 and PMID:25761413 Pdha1 Rat resveratrol multiple interactions ISO Pdha1 (Mus musculus) 6480464 dorsomorphin inhibits the reaction [Resveratrol results in increased expression of PDHA1 protein] and PRKAA1 gene mutant form inhibits the reaction [Resveratrol results in increased expression of PDHA1 protein] CTD PMID:25761413 Pdha1 Rat resveratrol multiple interactions EXP 6480464 [resveratrol results in increased activity of PDK4 protein] which results in increased phosphorylation of PDHA1 protein CTD PMID:23824959 Pdha1 Rat rotenone increases expression EXP 6480464 Rotenone results in increased expression of PDHA1 protein CTD PMID:35544339 Pdha1 Rat sodium arsenite decreases expression ISO PDHA1 (Homo sapiens) 6480464 sodium arsenite results in decreased expression of PDHA1 mRNA CTD PMID:38568856 Pdha1 Rat sodium arsenite decreases expression EXP 6480464 sodium arsenite results in decreased expression of PDHA1 mRNA CTD PMID:35314868 Pdha1 Rat sodium dodecyl sulfate decreases expression ISO PDHA1 (Homo sapiens) 6480464 Sodium Dodecyl Sulfate results in decreased expression of PDHA1 protein CTD PMID:21469165 Pdha1 Rat sodium fluoride increases expression ISO Pdha1 (Mus musculus) 6480464 Sodium Fluoride results in increased expression of PDHA1 protein CTD PMID:28918527 Pdha1 Rat superoxide affects abundance ISO PDHA1 (Homo sapiens) 6480464 PDHA1 protein affects the abundance of Superoxides CTD PMID:21846590 Pdha1 Rat temozolomide increases expression ISO PDHA1 (Homo sapiens) 6480464 Temozolomide results in increased expression of PDHA1 mRNA CTD PMID:31758290 Pdha1 Rat thiram decreases expression ISO PDHA1 (Homo sapiens) 6480464 Thiram results in decreased expression of PDHA1 mRNA CTD PMID:38568856 Pdha1 Rat titanium dioxide decreases expression ISO Pdha1 (Mus musculus) 6480464 titanium dioxide results in decreased expression of PDHA1 mRNA CTD PMID:23557971 Pdha1 Rat triclosan decreases expression ISO PDHA1 (Homo sapiens) 6480464 Triclosan results in decreased expression of PDHA1 mRNA CTD PMID:30510588 Pdha1 Rat valproic acid affects expression ISO PDHA1 (Homo sapiens) 6480464 Valproic Acid affects the expression of PDHA1 mRNA CTD PMID:25979313 Pdha1 Rat valproic acid increases expression ISO PDHA1 (Homo sapiens) 6480464 Valproic Acid results in increased expression of PDHA1 mRNA CTD PMID:23179753 and PMID:25192806 Pdha1 Rat zearalenone increases expression ISO Pdha1 (Mus musculus) 6480464 Zearalenone results in increased expression of PDHA1 protein CTD PMID:25058043