(+)-catechin multiple interactions ISO RGD:736556 6480464 [Catechin co-treated with Grape Seed Proanthocyanidins] results in increased expression of PDHA1 mRNA CTD PMID:24763279 (-)-epigallocatechin 3-gallate multiple interactions ISO RGD:736556 6480464 Acetylcysteine inhibits the reaction [epigallocatechin gallate results in decreased expression of PDHA1 mRNA], Acetylcysteine inhibits the reaction [epigallocatechin gallate results in decreased expression of PDHA1 protein] CTD PMID:31857147 (-)-epigallocatechin 3-gallate decreases expression ISO RGD:736556 6480464 epigallocatechin gallate results in decreased expression of PDHA1 mRNA, epigallocatechin gallate results in decreased expression of PDHA1 protein CTD PMID:31857147 1,2-dimethylhydrazine multiple interactions ISO RGD:736557 6480464 [1, 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of PDHA1 mRNA CTD PMID:22206623 17alpha-ethynylestradiol multiple interactions ISO RGD:736557 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of PDHA1 mRNA CTD PMID:17942748 17beta-estradiol multiple interactions EXP 6480464 [bisphenol A co-treated with Estradiol] results in decreased expression of PDHA1 mRNA CTD PMID:26496021 2,3,7,8-tetrabromodibenzodioxine affects expression ISO RGD:736557 6480464 2 more ... CTD PMID:27604104 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:736557 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of PDHA1 mRNA CTD PMID:17942748 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of PDHA1 mRNA CTD PMID:34747641 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of PDHA1 mRNA CTD PMID:32109520 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:736557 6480464 Tetrachlorodibenzodioxin affects the expression of PDHA1 mRNA CTD PMID:21570461 2,3,7,8-Tetrachlorodibenzofuran decreases expression EXP 6480464 2 more ... CTD PMID:32109520 3-chloropropane-1,2-diol increases expression EXP 6480464 alpha-Chlorohydrin results in increased expression of PDHA1 mRNA, alpha-Chlorohydrin results in increased expression of PDHA1 protein CTD PMID:26072098 , PMID:28522335 4,4'-diaminodiphenylmethane increases expression ISO RGD:736557 6480464 4, 4'-diaminodiphenylmethane results in increased expression of PDHA1 mRNA CTD PMID:18648102 aflatoxin B1 increases methylation ISO RGD:736556 6480464 Aflatoxin B1 results in increased methylation of PDHA1 intron CTD PMID:30157460 aldehydo-D-glucose multiple interactions ISO RGD:736556 6480464 Glucose inhibits the reaction [Dichloroacetic Acid results in decreased phosphorylation of PDHA1 protein] CTD PMID:31654802 all-trans-retinoic acid decreases expression ISO RGD:736556 6480464 Tretinoin results in decreased expression of PDHA1 mRNA CTD PMID:21934132 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of PDHA1 mRNA CTD PMID:16483693 Aroclor 1254 decreases expression ISO RGD:736557 6480464 Chlorodiphenyl (54% Chlorine) results in decreased expression of PDHA1 mRNA CTD PMID:23650126 arsenite(3-) multiple interactions ISO RGD:736556 6480464 arsenite inhibits the reaction [G3BP1 protein binds to PDHA1 protein], arsenite promotes the reaction [G3BP1 protein binds to PDHA1 mRNA] CTD PMID:32406909 arsenous acid increases expression ISO RGD:736556 6480464 Arsenic Trioxide results in increased expression of PDHA1 mRNA CTD PMID:22521957 atrazine decreases expression ISO RGD:736556 6480464 Atrazine results in decreased expression of PDHA1 mRNA CTD PMID:22378314 benzo[a]pyrene multiple interactions ISO RGD:736557 6480464 Benzo(a)pyrene promotes the reaction [AHR protein binds to PDHA1 promoter] CTD PMID:19654925 benzo[a]pyrene affects methylation ISO RGD:736556 6480464 Benzo(a)pyrene affects the methylation of PDHA1 5' UTR, Benzo(a)pyrene affects the methylation of PDHA1 promoter CTD PMID:27901495 benzo[a]pyrene decreases expression ISO RGD:736557 6480464 Benzo(a)pyrene results in decreased expression of PDHA1 mRNA CTD PMID:22228805 bezafibrate increases expression EXP 6480464 Bezafibrate results in increased expression of PDHA1 mRNA CTD PMID:11527545 bisphenol A increases expression ISO RGD:736557 6480464 bisphenol A results in increased expression of PDHA1 mRNA CTD PMID:22687993 bisphenol A multiple interactions ISO RGD:736556 6480464 [bisphenol A co-treated with Fulvestrant] results in decreased methylation of PDHA1 gene CTD PMID:31601247 bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of PDHA1 mRNA CTD PMID:34947998 bisphenol A decreases expression ISO RGD:736556 6480464 bisphenol A results in decreased expression of PDHA1 mRNA CTD PMID:29275510 bisphenol A increases methylation EXP 6480464 bisphenol A results in increased methylation of PDHA1 gene CTD PMID:28505145 bisphenol A increases methylation ISO RGD:736557 6480464 bisphenol A results in increased methylation of PDHA1 promoter CTD PMID:27312807 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of PDHA1 mRNA CTD PMID:25181051 bisphenol A multiple interactions EXP 6480464 [bisphenol A co-treated with Estradiol] results in decreased expression of PDHA1 mRNA CTD PMID:26496021 bisphenol A decreases expression ISO RGD:736557 6480464 bisphenol A results in decreased expression of PDHA1 mRNA CTD PMID:22687993 cadmium atom decreases expression ISO RGD:736556 6480464 Cadmium results in decreased expression of PDHA1 mRNA CTD PMID:23369406 ciguatoxin CTX1B affects expression ISO RGD:736557 6480464 Ciguatoxins affects the expression of PDHA1 mRNA CTD PMID:18353800 cobalt dichloride decreases expression ISO RGD:736556 6480464 cobaltous chloride results in decreased expression of PDHA1 mRNA CTD PMID:19376846 D-glucose multiple interactions ISO RGD:736556 6480464 Glucose inhibits the reaction [Dichloroacetic Acid results in decreased phosphorylation of PDHA1 protein] CTD PMID:31654802 dexamethasone increases expression ISO RGD:736556 6480464 Dexamethasone results in increased expression of PDHA1 mRNA CTD PMID:25047013 diarsenic trioxide increases expression ISO RGD:736556 6480464 Arsenic Trioxide results in increased expression of PDHA1 mRNA CTD PMID:22521957 dichloroacetic acid decreases phosphorylation ISO RGD:736556 6480464 Dichloroacetic Acid results in decreased phosphorylation of PDHA1 protein CTD PMID:25630799 , PMID:31654802 dichloroacetic acid multiple interactions ISO RGD:736556 6480464 Glucose inhibits the reaction [Dichloroacetic Acid results in decreased phosphorylation of PDHA1 protein] CTD PMID:31654802 dinophysistoxin 1 affects expression ISO RGD:736556 6480464 dinophysistoxin 1 affects the expression of PDHA1 mRNA CTD PMID:28939011 diuron decreases expression EXP 6480464 Diuron results in decreased expression of PDHA1 mRNA CTD PMID:21551480 dorsomorphin multiple interactions ISO RGD:736557 6480464 dorsomorphin inhibits the reaction [Resveratrol results in increased expression of PDHA1 protein] CTD PMID:25761413 doxorubicin increases phosphorylation ISO RGD:736557 6480464 Doxorubicin results in increased phosphorylation of PDHA1 mRNA CTD PMID:29653124 doxorubicin decreases expression ISO RGD:736556 6480464 Doxorubicin results in decreased expression of PDHA1 mRNA CTD PMID:29803840 duvoglustat multiple interactions ISO RGD:736557 6480464 [1-Deoxynojirimycin co-treated with Polysaccharides] results in increased expression of PDHA1 mRNA CTD PMID:25446853 ethanol increases expression ISO RGD:736557 6480464 Ethanol results in increased expression of PDHA1 mRNA CTD PMID:19167417 ethanol increases expression EXP 6480464 Ethanol results in increased expression of PDHA1 protein CTD PMID:19609968 , PMID:23702218 flutamide increases expression EXP 6480464 Flutamide results in increased expression of PDHA1 mRNA CTD PMID:24136188 folic acid decreases expression ISO RGD:736557 6480464 Folic Acid results in decreased expression of PDHA1 mRNA CTD PMID:25629700 folic acid multiple interactions ISO RGD:736557 6480464 [1, 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of PDHA1 mRNA CTD PMID:22206623 formaldehyde decreases expression ISO RGD:736556 6480464 Formaldehyde results in decreased expression of PDHA1 mRNA CTD PMID:23649840 fulvestrant multiple interactions ISO RGD:736556 6480464 [bisphenol A co-treated with Fulvestrant] results in decreased methylation of PDHA1 gene CTD PMID:31601247 Fusaric acid increases phosphorylation ISO RGD:736556 6480464 Fusaric Acid results in increased phosphorylation of PDHA1 protein CTD PMID:31654802 Fusaric acid decreases phosphorylation ISO RGD:736557 6480464 Fusaric Acid results in decreased phosphorylation of PDHA1 protein CTD PMID:32156565 genistein increases methylation EXP 6480464 Genistein results in increased methylation of PDHA1 gene CTD PMID:28505145 gentamycin increases expression EXP 6480464 Gentamicins results in increased expression of PDHA1 mRNA CTD PMID:22061828 glucose multiple interactions ISO RGD:736556 6480464 Glucose inhibits the reaction [Dichloroacetic Acid results in decreased phosphorylation of PDHA1 protein] CTD PMID:31654802 hydrogen peroxide multiple interactions ISO RGD:736557 6480464 [Hydrogen Peroxide co-treated with N-(oxo-5 more ... CTD PMID:31494107 isotretinoin decreases expression ISO RGD:736556 6480464 Isotretinoin results in decreased expression of PDHA1 mRNA CTD PMID:20436886 ivermectin decreases expression ISO RGD:736556 6480464 Ivermectin results in decreased expression of PDHA1 protein CTD PMID:32959892 kojic acid increases expression ISO RGD:736556 6480464 kojic acid results in increased expression of PDHA1 mRNA CTD PMID:16595896 maneb multiple interactions ISO RGD:736557 6480464 [Maneb co-treated with Paraquat] results in decreased expression of PDHA1 mRNA more ... CTD PMID:23562983 , PMID:23963992 metformin multiple interactions ISO RGD:736556 6480464 Metformin results in decreased phosphorylation of and results in increased activity of PDHA1 protein CTD PMID:28576465 methamphetamine decreases expression EXP 6480464 Methamphetamine results in decreased expression of PDHA1 protein CTD PMID:19826936 methyl methanesulfonate decreases expression ISO RGD:736556 6480464 Methyl Methanesulfonate results in decreased expression of PDHA1 mRNA CTD PMID:23649840 Methylazoxymethanol acetate increases expression EXP 6480464 Methylazoxymethanol Acetate results in increased expression of PDHA1 mRNA CTD PMID:28349193 methylmercury chloride decreases expression ISO RGD:736556 6480464 methylmercuric chloride results in decreased expression of PDHA1 mRNA CTD PMID:28001369 methylparaben increases expression ISO RGD:736556 6480464 methylparaben results in increased expression of PDHA1 mRNA CTD PMID:31745603 mitoxantrone decreases expression ISO RGD:736557 6480464 Mitoxantrone results in decreased expression of PDHA1 protein CTD PMID:34246718 N-acetyl-L-cysteine multiple interactions ISO RGD:736556 6480464 Acetylcysteine inhibits the reaction [epigallocatechin gallate results in decreased expression of PDHA1 mRNA], Acetylcysteine inhibits the reaction [epigallocatechin gallate results in decreased expression of PDHA1 protein] CTD PMID:31857147 nefazodone increases expression EXP 6480464 nefazodone results in increased expression of PDHA1 mRNA CTD PMID:24136188 okadaic acid increases expression ISO RGD:736556 6480464 Okadaic Acid results in increased expression of PDHA1 mRNA CTD PMID:28939011 paracetamol decreases expression ISO RGD:736556 6480464 Acetaminophen results in decreased expression of PDHA1 mRNA CTD PMID:25704631 paraquat multiple interactions ISO RGD:736557 6480464 [Maneb co-treated with Paraquat] results in decreased expression of PDHA1 mRNA more ... CTD PMID:23562983 , PMID:23963992 PCB138 increases expression EXP 6480464 2 more ... CTD PMID:21673325 perfluorooctanoic acid multiple interactions ISO RGD:736557 6480464 Dietary Fats, Unsaturated inhibits the reaction [perfluorooctanoic acid results in increased expression of PDHA1 mRNA] CTD PMID:23626681 perfluorooctanoic acid increases expression ISO RGD:736556 6480464 perfluorooctanoic acid results in increased expression of PDHA1 protein CTD PMID:26879310 picoxystrobin increases expression ISO RGD:736556 6480464 picoxystrobin results in increased expression of PDHA1 mRNA CTD PMID:33512557 pirinixic acid increases expression EXP 6480464 pirinixic acid results in increased expression of PDHA1 mRNA CTD PMID:11527545 , PMID:19162173 pirinixic acid increases expression ISO RGD:736557 6480464 pirinixic acid results in increased expression of PDHA1 mRNA CTD PMID:23811191 pregnenolone 16alpha-carbonitrile increases expression ISO RGD:736557 6480464 Pregnenolone Carbonitrile results in increased expression of PDHA1 mRNA CTD PMID:28903501 quinoline increases expression ISO RGD:736556 6480464 quinoline analog results in increased expression of PDHA1 protein CTD PMID:18645022 resveratrol decreases expression ISO RGD:736556 6480464 resveratrol results in decreased expression of PDHA1 mRNA CTD PMID:15582268 resveratrol increases expression ISO RGD:736557 6480464 resveratrol results in increased expression of PDHA1 protein CTD PMID:25505154 , PMID:25761413 resveratrol multiple interactions ISO RGD:736557 6480464 dorsomorphin inhibits the reaction [Resveratrol results in increased expression of PDHA1 protein], PRKAA1 gene mutant form inhibits the reaction [Resveratrol results in increased expression of PDHA1 protein] CTD PMID:25761413 resveratrol multiple interactions EXP 6480464 [resveratrol results in increased activity of PDK4 protein] which results in increased phosphorylation of PDHA1 protein CTD PMID:23824959 sodium dodecyl sulfate decreases expression ISO RGD:736556 6480464 Sodium Dodecyl Sulfate results in decreased expression of PDHA1 protein CTD PMID:21469165 sodium fluoride increases expression ISO RGD:736557 6480464 Sodium Fluoride results in increased expression of PDHA1 protein CTD PMID:28918527 superoxide affects abundance ISO RGD:736556 6480464 PDHA1 protein affects the abundance of Superoxides CTD PMID:21846590 temozolomide increases expression ISO RGD:736556 6480464 Temozolomide results in increased expression of PDHA1 mRNA CTD PMID:31758290 titanium dioxide decreases expression ISO RGD:736557 6480464 titanium dioxide results in decreased expression of PDHA1 mRNA CTD PMID:23557971 triclosan decreases expression ISO RGD:736556 6480464 Triclosan results in decreased expression of PDHA1 mRNA CTD PMID:30510588 valproic acid affects expression ISO RGD:736556 6480464 Valproic Acid affects the expression of PDHA1 mRNA CTD PMID:25979313 valproic acid increases expression ISO RGD:736556 6480464 Valproic Acid results in increased expression of PDHA1 mRNA CTD PMID:23179753 , PMID:25192806 zearalenone increases expression ISO RGD:736557 6480464 Zearalenone results in increased expression of PDHA1 protein CTD PMID:25058043