Dvl3 (dishevelled segment polarity protein 3)

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Gene: Dvl3 (dishevelled segment polarity protein 3) Rattus norvegicus

Analyze

Symbol:

Dvl3

Name:

dishevelled segment polarity protein 3

RGD ID:

1308834

Description:

Exhibits signaling receptor binding activity. Involved in positive regulation of neuron projection arborization and response to drug. Predicted to localize to several cellular components, including Wnt signalosome; chromatin; and glutamatergic synapse. Human ortholog(s) of this gene implicated in autosomal dominant Robinow syndrome 3. Orthologous to human DVL3 (dishevelled segment polarity protein 3); PARTICIPATES IN Wnt signaling pathway; Wnt signaling, canonical pathway; Wnt signaling, non-canonical pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; clozapine.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Also known as:

dishevelled 3, dsh homolog; dishevelled 3, dsh homolog (Drosophila) ; dishevelled, dsh homolog 3; dishevelled, dsh homolog 3 (Drosophila); LOC303811; segment polarity protein dishevelled homolog DVL-3

RGD Orthologs

Human

Mouse

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

Latest Assembly:

Rnor_6.0 - RGSC Genome Assembly v6.0

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	11	80,365,446 - 80,382,641 (-)	NCBI
Rnor_6.0 Ensembl	11	84,051,078 - 84,068,302 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_6.0	11	84,051,177 - 84,068,479 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	11	87,123,483 - 87,139,802 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	11	82,597,654 - 82,622,175 (-)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	11	82,654,389 - 82,679,764 (-)	NCBI
Celera	11	79,207,145 - 79,222,292 (-)	NCBI		Celera
Cytogenetic Map	11	q23	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autosomal dominant Robinow syndrome 1 (ISO)

autosomal dominant Robinow syndrome 2 (ISO)

autosomal dominant Robinow syndrome 3 (ISO)

Currarino syndrome (ISO)

Dwarfism (ISO)

Robinow syndrome (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

2,2',4,4',5,5'-hexachlorobiphenyl (ISO)

2,2',5,5'-tetrachlorobiphenyl (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2-methylcholine (ISO)

5-aza-2'-deoxycytidine (ISO)

antirheumatic drug (ISO)

arsane (ISO)

arsenic atom (ISO)

atrazine (ISO)

benzo[a]pyrene (ISO)

benzo[b]fluoranthene (ISO)

bisphenol A (EXP)

buta-1,3-diene (ISO)

carbon nanotube (ISO)

chrysene (ISO)

clobetasol (ISO)

clozapine (EXP)

copper atom (EXP)

copper(0) (EXP)

crocidolite asbestos (ISO)

diazinon (EXP)

dicrotophos (ISO)

diethylstilbestrol (EXP)

ethanol (ISO)

ethyl methanesulfonate (ISO)

folic acid (ISO)

glyphosate (ISO)

haloperidol (EXP)

Indeno[1,2,3-cd]pyrene (ISO)

methyl methanesulfonate (ISO)

methylseleninic acid (ISO)

N-ethyl-N-nitrosourea (ISO)

niclosamide (ISO)

Nor-9-carboxy-delta9-THC (ISO)

oxaliplatin (ISO)

paracetamol (ISO)

PCB138 (ISO)

pirinixic acid (ISO)

risperidone (EXP)

Salinomycin (ISO)

sodium arsenite (ISO)

tert-butyl hydroperoxide (ISO)

tetraphene (ISO)

tremolite asbestos (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

canonical Wnt signaling pathway (IBA,ISO)

cochlea morphogenesis (ISO)

heart morphogenesis (ISO)

intracellular signal transduction (IEA)

non-canonical Wnt signaling pathway (ISO)

non-canonical Wnt signaling pathway via JNK cascade (ISO)

outflow tract septum morphogenesis (ISO)

planar cell polarity pathway involved in neural tube closure (IBA,ISO)

positive regulation of GTPase activity (ISO)

positive regulation of JUN kinase activity (ISO)

positive regulation of neuron projection arborization (IGI)

positive regulation of protein phosphorylation (ISO)

positive regulation of transcription by RNA polymerase II (ISO)

positive regulation of transcription, DNA-templated (ISO)

protein stabilization (ISO)

regulation of cellular protein localization (ISO)

response to drug (IEP)

Wnt signaling pathway, planar cell polarity pathway (ISO)

Cellular Component

cellular_component (ND)

chromatin (ISO)

cytoplasm (ISO)

cytosol (IBA,ISO,TAS)

glutamatergic synapse (ISO)

synapse (ISO)

Wnt signalosome (ISO)

Molecular Function

beta-catenin binding (ISO)

frizzled binding (IBA,ISO)

protease binding (ISO)

protein binding (IPI,ISO)

protein-macromolecule adaptor activity (ISO)

signaling receptor binding (IPI,ISO)

small GTPase binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

basal cell carcinoma pathway (IEA)

Notch signaling pathway (IEA)

Wnt signaling pathway (IEA,ISO)

Wnt signaling, canonical pathway (ISO)

Wnt signaling, non-canonical pathway (ISO)

References

References - curated


1.	Bian WJ, etal., Dev Neurobiol. 2015 Aug;75(8):805-22. doi: 10.1002/dneu.22250. Epub 2014 Dec 1.
2.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.	GOA data from the GO Consortium
4.	Kishida S, etal., Mol Cell Biol. 1999 Jun;19(6):4414-22.
5.	MGD data from the GO Consortium
6.	Pipeline to import KEGG annotations from KEGG into RGD
7.	Pipeline to import Pathway Interaction Database annotations from NCI into RGD
8.	RGD automated data pipeline
9.	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
10.	RGD automated import pipeline for gene-chemical interactions
11.	RGD comprehensive gene curation
12.	Roel Nusse - Howard Hughes Medical Institute and the Department of Developmental Biology at Stanford University, California, USA
13.	Sutton LP, etal., J Neurochem. 2007 Jul;102(1):153-69. Epub 2007 May 1.

Additional References at PubMed

PMID:10644691	PMID:11274398	PMID:12805222	PMID:16501258	PMID:17005174	PMID:17030191	PMID:17593335	PMID:18093802	PMID:19008950	PMID:19137009	PMID:19388021	PMID:19625296
PMID:20137080	PMID:20227366	PMID:21718540	PMID:21880741	PMID:22899650	PMID:23109420	PMID:26359454	PMID:30808893

Genomics

Comparative Map Data

Dvl3
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	11	80,365,446 - 80,382,641 (-)	NCBI
Rnor_6.0 Ensembl	11	84,051,078 - 84,068,302 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_6.0	11	84,051,177 - 84,068,479 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	11	87,123,483 - 87,139,802 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	11	82,597,654 - 82,622,175 (-)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	11	82,654,389 - 82,679,764 (-)	NCBI
Celera	11	79,207,145 - 79,222,292 (-)	NCBI		Celera
Cytogenetic Map	11	q23	NCBI

DVL3
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38.p13 Ensembl	3	184,155,377 - 184,173,614 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh38	3	184,155,311 - 184,173,614 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh37	3	183,873,165 - 183,891,402 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	3	185,355,978 - 185,374,008 (+)	NCBI	NCBI36		hg18	NCBI36
Build 34	3	185,355,985 - 185,374,016	NCBI
Celera	3	182,315,580 - 182,333,025 (+)	NCBI
Cytogenetic Map	3	q27.1	NCBI
HuRef	3	181,280,976 - 181,298,206 (+)	NCBI		HuRef
CHM1_1	3	183,837,689 - 183,855,719 (+)	NCBI		CHM1_1

Dvl3
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	16	20,335,694 - 20,352,763 (+)	NCBI	GRCm39		mm39
GRCm39 Ensembl	16	20,335,732 - 20,352,760 (+)	Ensembl
GRCm38	16	20,516,949 - 20,534,013 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	16	20,516,982 - 20,534,010 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	16	20,517,137 - 20,532,260 (+)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	16	20,430,525 - 20,445,193 (+)	NCBI			mm8
Celera	16	21,081,348 - 21,096,276 (+)	NCBI		Celera
Cytogenetic Map	16	A3	NCBI
cM Map	16	12.46	NCBI

Dvl3
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955420	23,293,222 - 23,301,694 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955420	23,291,650 - 23,301,695 (-)	NCBI	ChiLan1.0	ChiLan1.0

DVL3
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	3	189,674,405 - 189,691,749 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	3	189,674,399 - 189,693,130 (+)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	3	181,190,961 - 181,207,831 (+)	NCBI	Mhudiblu_PPA_v0		panPan3

DVL3
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	34	17,053,534 - 17,069,965 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	34	17,053,343 - 17,068,389 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	34	21,140,844 - 21,154,943 (+)	NCBI
ROS_Cfam_1.0	34	16,961,718 - 16,975,817 (+)	NCBI
UMICH_Zoey_3.1	34	16,999,057 - 17,013,143 (+)	NCBI
UNSW_CanFamBas_1.0	34	16,995,018 - 17,011,464 (+)	NCBI
UU_Cfam_GSD_1.0	34	17,225,218 - 17,241,675 (+)	NCBI

Dvl3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405602	119,602,013 - 119,618,283 (-)	NCBI
SpeTri2.0	NW_004936578	5,693,433 - 5,710,137 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

DVL3
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	13	122,076,003 - 122,092,971 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	13	122,075,851 - 122,092,975 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	13	131,521,353 - 131,532,563 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

DVL3
(Chlorocebus sabaeus - African green monkey)

Vervet Assembly	Chr	Position (strand)	Source	Genome Browsers
Vervet Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	15	5,254,764 - 5,270,661 (-)	NCBI
ChlSab1.1 Ensembl	15	5,254,661 - 5,270,403 (-)	Ensembl

Dvl3
(Heterocephalus glaber - naked mole-rat)

Molerat Assembly	Chr	Position (strand)	Source	Genome Browsers
Molerat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624730	72,396,437 - 72,412,260 (-)	NCBI

Position Markers

RH127970

Rat Assembly	Chr	Position (strand)	Source	JBrowse
Rnor_6.0	11	84,051,273 - 84,051,458	NCBI	Rnor6.0
Rnor_6.0	7	120,375,647 - 120,375,832	NCBI	Rnor6.0
Rnor_5.0	11	87,123,585 - 87,123,770	UniSTS	Rnor5.0
Rnor_5.0	7	120,369,726 - 120,369,911	UniSTS	Rnor5.0
RGSC_v3.4	11	82,595,563 - 82,595,748	UniSTS	RGSC3.4
RGSC_v3.4	7	117,117,919 - 117,118,104	UniSTS	RGSC3.4
Celera	7	107,042,159 - 107,042,344	UniSTS
Celera	11	79,204,941 - 79,205,126	UniSTS
RH 3.4 Map	11	654.01	UniSTS
Cytogenetic Map	7	q34	UniSTS
Cytogenetic Map	11	q23	UniSTS

UniSTS:532277

Rat Assembly	Chr	Position (strand)	Source	JBrowse
Rnor_6.0	11	84,053,534 - 84,054,024	NCBI	Rnor6.0
Rnor_5.0	11	87,125,846 - 87,126,336	UniSTS	Rnor5.0
Celera	11	79,207,202 - 79,207,692	UniSTS
Cytogenetic Map	11	q23	UniSTS

QTLs in Region (Rnor_6.0)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
724554	Iddm17	Insulin dependent diabetes mellitus QTL 17		0.001	blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	11	19016272	90463843	Rat
724563	Uae10	Urinary albumin excretion QTL 10	6		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	11	28314665	86994795	Rat
1300110	Stl7	Serum triglyceride level QTL 7	4.64		blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	11	30435339	86714631	Rat
1300135	Rf19	Renal function QTL 19	3.38		blood creatinine amount (VT:0005328)	creatinine clearance (CMO:0000765)	11	43090338	86714631	Rat
2312566	Glom20	Glomerulus QTL 20	3.6	0.001	kidney glomerulus morphology trait (VT:0005325)	index of glomerular damage (CMO:0001135)	11	46583209	86714631	Rat
1581565	Pur10	Proteinuria QTL 10		0.0001	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	11	47264023	86994547	Rat
1581572	Uae35	Urinary albumin excretion QTL 35		0.0001	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	11	47264023	86994547	Rat
724561	Plsm4	Polydactyly-luxate syndrome (PLS) morphotypes QTL 4		0.0003	forelimb integrity trait (VT:0010562)	front foot phalanges count (CMO:0001947)	11	57858810	90463843	Rat
7411658	Foco27	Food consumption QTL 27	16.2	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	11	59943023	90463843	Rat
4889521	Gluco62	Glucose level QTL 62	2.82	0.001	blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	11	60109842	87141948	Rat
631506	Bp104	Blood pressure QTL 104	2.8		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	11	62653365	86714475	Rat
70208	Niddm22	Non-insulin dependent diabetes mellitus QTL 22	3.61		blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	11	62653365	86714483	Rat
10058954	Gmadr7	Adrenal mass QTL 7	2.49	0.0049	adrenal gland mass (VT:0010420)	both adrenal glands wet weight to body weight ratio (CMO:0002411)	11	64494671	90463843	Rat
1549848	Bvd6	Brain ventricular dilatation QTL 6	3.1	0.0001	brain ventricle morphology trait (VT:0000822)	hydrocephalus severity score (CMO:0001881)	11	69342319	86312439	Rat
1354593	Stl12	Serum triglyceride level QTL 12	3.36		blood triglyceride amount (VT:0002644)	serum triglyceride level (CMO:0000360)	11	69649708	90463843	Rat
1354656	Bvd3	Brain ventricular dilatation QTL 3	3.64	0.001	brain ventricle morphology trait (VT:0000822)	hydrocephalus severity score (CMO:0001881)	11	72720029	86994795	Rat
10450831	Scl80	Serum cholesterol level QTL 80	4.7	0.01	blood LDL cholesterol amount (VT:0000181)	blood low density lipoprotein cholesterol level (CMO:0000053)	11	80358408	87200449	Rat

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	40
Count of miRNA genes:	40
Interacting mature miRNAs:	40
Transcripts:	ENSRNOT00000002323
Prediction methods:	Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	3	34	31	31	5	31		3	66	27	33	3
Low		9	26	10	14	10	8	8	8	8	8	8	8
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001107081	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006248564	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006248565	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006248566	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC110855	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473999	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000222	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSRNOT00000002323 ⟹ ENSRNOP00000002323

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	11	84,051,078 - 84,068,302 (-)	Ensembl

RefSeq Acc Id:

NM_001107081 ⟹ NP_001100551

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	11	80,367,752 - 80,382,247 (-)	NCBI
Rnor_6.0	11	84,053,477 - 84,068,087 (-)	NCBI
Rnor_5.0	11	87,123,483 - 87,139,802 (-)	NCBI
RGSC_v3.4	11	82,597,654 - 82,622,175 (-)	RGD
Celera	11	79,207,145 - 79,222,292 (-)	NCBI

Sequence:

show sequence

ATGGACGACGATTTTGGAGTGGTGAAGGAAGAGATCTCGGATGACAATGCCAAGCTGCCCTGCT
TCAATGGCCGGGTGGTGTCCTGGCTGGTATCGGCCGAGGGCTCACACCCAGAGCCAGCCCCTTT
CTGTGCTGACAACCCCTCAGAGCTGCCTCCTTCAATGGAACGCACAGGAGGCATCGGTGACTCT
CGGCCCCCGTCCTTCCACCCTCATGCTAGTGGGGGCAGCCAGGAGAACTTGGACAATGACACAG
AGACCGACTCCTTGGTATCTGCCCAACGAGAGCGGCCCAGACGGAGGGATGGCCCTGAGCACGC
AGCCCGCCTCAATGGAACCACAAAGGGCGAGCGGCGACGGGAGCCAGGTGGCTATGACAGTTCA
TCTACCCTCATGAGCAGCGAGCTGGAGACTACCAGTTTCTTTGATTCAGATGAGGATGACTCCA
CCAGCAGGTTCAGCAGCTCCACAGAACAGAGCAGTGCCTCACGCCTAATGAGAAGACACAAGCG
GCGGCGACGGAAGCAGAAGGTCTCCCGGATTGAGCGGTCCTCCTCCTTCAGCAGCATCACAGAC
TCCACTATGTCTCTCAACATCATCACAGTGACTCTCAACATGGAAAAGTATAACTTCTTGGGCA
TCTCCATTGTGGGCCAGAGCAATGAGCGAGGTGATGGGGGCATCTACATTGGCTCCATCATGAA
GGGTGGGGCAGTGGCGGCTGATGGACGCATTGAGCCGGGAGATATGCTGTTGCAGGTAAATGAG
ATCAACTTCGAGAACATGAGTAATGATGACGCAGTCAGAGTGCTTCGGGAGATCGTGCACAAAC
CAGGGCCCATCACTCTGACTGTAGCCAAGTGCTGGGACCCAAGTCCTCGTGGCTGCTTCACATT
ACCCCGGAGTGAGCCCATCCGTCCCATTGACCCTGCAGCCTGGGTCTCCCACACTGCAGCCATG
ACAGGAACCTTCCCTGCCTATGGCATGAGCCCCTCCTTAAGCACCATCACCTCCACCAGCTCCT
CCATCACCAGCTCCATCCCCGACACAGAACGCCTAGATGATTTCCACCTCTCCATCCACAGTGA
CATGGCGGCCATCGTAAAAGCCATGGCCTCCCCCGAGTCAGGGCTGGAGGTCCGAGACCGCATG
TGGCTCAAGATTACCATTCCCAATGCTTTCATCGGCTCAGATGTGGTGGACTGGCTGTATCACA
ATGTGGAAGGATTCACCGACCGGCGGGAGGCCCGCAAGTACGCTAGCAACCTGCTGAAGGCTGG
ATTCATCCGCCACACGGTCAACAAGATCACGTTCTCTGAGCAGTGCTACTACATCTTTGGTGAC
CTCTGTGGCAACATGGCCAACCTATCGCTGCACGACCATGATGGCTCCAGTGGTGCCTCTGACC
AGGACACACTGGCTCCTCTGCCGCACCCAGGGGCTGCCCCTTGGCCTATGGCTTTCCCTTACCA
GTACCCACCACCTCCGCACCCGTACAACCCACACCCAGGCTTCCCGGAGCTGGGCTACAGCTAC
GCTGGGGGCAGCGCCAGCAGTCAGCACAGTGAAGGTAGTAGGAGCAGTGGCTCCAACCGAAGTG
GCAGCGACCGGCGCAAGGAGAAGGACCCAAAAGCTGGGGACTCAAAGTCAGGTGGTAGCGGCAG
CGAGTCAGACCACACTACACGCAGCAGTCTGCGGGGGCCACGGGAGCGGGCACCAAGCGAGCGC
TCAGGCCCAGCGGCCAGCGAGCACAGCCACCGCAGTCATCATTCACTGACCAGTAGCCTGCGCA
GCCACCACACACACCCAAGCTATGGCCCACCCGGAGTGCCCCCTCTCTATGGTCCCCCGATGCT
GATGATGACCCCACCGCCTGCAGCCATGGGGCCCCCAGGAGCCCCTCCAGGGCGTGACCTGGCC
TCGGTGCCCCCGGAACTGACGGCCAGCAGACAGTCCTTCCGCATGGCAATGGGAAACCCCAGTG
AGTTCTTTGTGGATGTGATGTGA

hide sequence

RefSeq Acc Id:

XM_006248564 ⟹ XP_006248626

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	11	80,365,446 - 80,382,641 (-)	NCBI
Rnor_6.0	11	84,051,177 - 84,068,479 (-)	NCBI
Rnor_5.0	11	87,123,483 - 87,139,802 (-)	NCBI

Sequence:

show sequence

GGCCCAGAGCCGGGAGGGCCGAGGCCACCGGAAGAGTCGCGGTCGCCAGCCGAGCGCTGTGAGT
GGGGAGCGGAAGCGGTGGCGGGCGGCGCTGGGACCCGGGAGCGGCCGGAGAACAAGGGAGCTGG
CGCCCCGGCCGGCGGCTGAGCGGGGCTAAGCAGCGGGCCTCGCCGAGCGCCGAGCTCTGTCGGA
GAGGCCCGGCCCCGCTGCCCAAGCAGGCCGCACGCCGCGGGGCCGAGGCCGGAGCCATGGGCGA
GACTAAGATCATCTACCACTTGGACGGCCAGGAGACGCCGTACCTAGTGAAGCTGCCCCTGCCC
GCCGAGCGCGTCACCTTGGCGGACTTTAAGGGCGTTTTGCAGCGGCCCAGCTATAAGTTCTTCT
TCAAGTCTATGGACGACGATTTTGGAGTGGTGAAGGAAGAGATCTCGGATGACAATGCCAAGCT
GCCCTGCTTCAATGGCCGGGTGGTGTCCTGGCTGGTATCGGCCGAGGGCTCACACCCAGAGCCA
GCCCCTTTCTGTGCTGACAACCCCTCAGAGCTGCCTCCTTCAATGGAACGCACAGGAGGCATCG
GTGACTCTCGGCCCCCGTCCTTCCACCCTCATGCTAGTGGGGGCAGCCAGGAGAACTTGGACAA
TGACACAGAGACCGACTCCTTGGTATCTGCCCAACGAGAGCGGCCCAGACGGAGGGATGGCCCT
GAGCACGCAGCCCGCCTCAATGGAACCACAAAGGGCGAGCGGCGACGGGAGCCAGGTGGCTATG
ACAGTTCATCTACCCTCATGAGCAGCGAGCTGGAGACTACCAGTTTCTTTGATTCAGATGAGGA
TGACTCCACCAGCAGGTTCAGCAGCTCCACAGAACAGAGCAGTGCCTCACGCCTAATGAGAAGA
CACAAGCGGCGGCGACGGAAGCAGAAGGTCTCCCGGATTGAGCGGTCCTCCTCCTTCAGCAGCA
TCACAGACTCCACTATGTCTCTCAACATCATCACAGTGACTCTCAACATGGAAAAGTATAACTT
CTTGGGCATCTCCATTGTGGGCCAGAGCAATGAGCGAGGTGATGGGGGCATCTACATTGGCTCC
ATCATGAAGGGTGGGGCAGTGGCGGCTGATGGACGCATTGAGCCGGGAGATATGCTGTTGCAGG
TAAATGAGATCAACTTCGAGAACATGAGTAATGATGACGCAGTCAGAGTGCTTCGGGAGATCGT
GCACAAACCAGGGCCCATCACTCTGACTGTAGCCAAGTGCTGGGACCCAAGTCCTCGTGGCTGC
TTCACATTACCCCGGAGTGAGCCCATCCGTCCCATTGACCCTGCAGCCTGGGTCTCCCACACTG
CAGCCATGACAGGAACCTTCCCTGCCTATGGCATGAGCCCCTCCTTAAGCACCATCACCTCCAC
CAGCTCCTCCATCACCAGCTCCATCCCCGACACAGAACGCCTAGATGATTTCCACCTCTCCATC
CACAGTGACATGGCGGCCATCGTAAAAGCCATGGCCTCCCCCGAGTCAGGGCTGGAGGTCCGAG
ACCGCATGTGGCTCAAGATTACCATTCCCAATGCTTTCATCGGCTCAGATGTGGTGGACTGGCT
GTATCACAATGTGGAAGGATTCACCGACCGGCGGGAGGCCCGCAAGTACGCTAGCAACCTGCTG
AAGGCTGGATTCATCCGCCACACGGTCAACAAGATCACGTTCTCTGAGCAGTGCTACTACATCT
TTGGTGACCTCTGTGGCAACATGGCCAACCTATCGCTGCACGACCATGATGGCTCCAGTGGTGC
CTCTGACCAGGACACACTGGCTCCTCTGCCGCACCCAGGGGCTGCCCCTTGGCCTATGGCTTTC
CCTTACCAGTACCCACCACCTCCGCACCCGTACAACCCACACCCAGGCTTCCCGGAGCTGGGCT
ACAGCTACGCTGGGGGCAGCGCCAGCAGTCAGCACAGTGAAGGTAGTAGGAGCAGTGGCTCCAA
CCGAAGTGGCAGCGACCGGCGCAAGGAGAAGGACCCAAAAGCTGGGGACTCAAAGTCAGGTGGT
AGCGGCAGCGAGTCAGACCACACTACACGCAGCAGTCTGCGGGGGCCACGGGAGCGGGCACCAA
GCGAGCGCTCAGGCCCAGCGGCCAGCGAGCACAGCCACCGCAGTCATCATTCACTGACCAGTAG
CCTGCGCAGCCACCACACACACCCAAGCTATGGCCCACCCGGAGTGCCCCCTCTCTATGGTCCC
CCGATGCTGATGATGACCCCACCGCCTGCAGCCATGGGGCCCCCAGGAGCCCCTCCAGGGCGTG
ACCTGGCCTCGGTGCCCCCGGAACTGACGGCCAGCAGACAGTCCTTCCGCATGGCAATGGGAAA
CCCCACCAAGAATTTCGGGCTCTTTGACTTTCTGTGAGTCCCCAGGAAAGGGAGGCCCAGCCTC
CAAGGAGACCAGGAACTCTGCTTCAGCTCCCTCAGGGCTTCCCAAGGATGTCCAGCCCCCACAG
GACCCACACTTCAAGGTCACTAGGCTTTTGGGAAGGGCCTCAGCTTCCCCCATGCATAACTGAC
TACTCTTTTCAGAGAGAAGTAGAGAAGTTCGCTCCCCTCCACCTCATACACATAGATATACATA
CACATGTGAGTCTCTCCCCCCAACCCCTGGTCTCTGTCTCTCTGTCTCTGTCTCTGTCTCTCTC
TCACGCCTATGCAAGTTTACAGAAGCCTCAGGGCTGGTCCCTGGCCAGAGGGCTGGACCCTTTT
TCCAAGTCATCTCCTAGATAGTAGGGCTGGTCCCTGACGTCCTCTTCCCTTCAGCTAGCCCTTA
AGCTTCCCTTACATGTTCCCAACATCTTTGTACTTAGATAAAAGTCCAAAAGCTGGGGCTCACC
AGAGGGCTCTCCGGTAACTGACAGATCATTCTCTACTTCCCTTCTGCCCCACATCTCTGGGTAC
CTGCTCTGTTTCATCTTCCCCATGAACCCTGGGGACACAGGCCAGTTGAAGCTATACGAGCAGA
CAACTGGGGCTTCCAGACCGTTCCAGTTAACTGTTTTCTACCTTAAATCATAATTTCCTCCTTA
AAACACCGCTATAAACTCTGACTTATCCAGACTCTTTAAATTTTCAGTCAAGGGTGTCAGCTGA
GGAAATAGCTGTGTAGTGCTTGCCTAGCATGCCCCAGCAAATGTCTCCCCCATCAAGATGTCCT
TAGCCCAGGTTTGGGGGCAACCTGAGGTAGGGATATTTTGACATTCATTTAACATATTTCCAGG
GACTTTAATGAACAAAGGGCTATGTTAGAAGCATGACTTGATCTTCGCTGTCTTCAGTTCTCTC
TGACTCTGCCTTTTCCTGTTCTCTTGAGAATCCCTCACCAGTGCTCCCATTATCCTGCCTTTGG
CTCATGTCCCTTTCTTCCCCCCTTTCCCCCATAGTGTCAGCCACTCTCTTCTTAAGCTGTTGAT
GTGCTGGCCACTTCTAAATCTGGATCTCCCACCCCAGCTTCCCCTCTCTTTAGATCTGTTTTTA
TTCCCCACTGGACATCTCCCCAGGCTTGTCCATATGTCCCCAGCCAAGTATTATTCCTCTCGAA
TTCCTGCCCTTGTGACCTTCATTACAAGCCACACCTACACGGGCTTAGTCAGCATCTCACACCC
TTATACTCAGACACTCTGAAGTTCAGCTGTTCCTCTCCCTTCCTTACATTACAGAGCATGGGAT
TTGGAGTCAGGTTGGTTTGGGCTTGATTTCCAGCTCTATCATTTTTGATTGTGTAATAGAGTTA
TTTAACCTCTCTGGAGCCTCAGTCCTCCCATATGTAAAATGATGATAATAATACCTACCTCACA
GGGTTGTTGTGAGGATTTAAATTAGATATTGTACGAAAAGTGCCTAGCACAGTGCCTGGCACAT
AATAGAGTAGGTGCTCAATAAATGGTAGCTATTATTATTACTA

hide sequence

RefSeq Acc Id:

XM_006248565 ⟹ XP_006248627

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	11	80,365,446 - 80,382,641 (-)	NCBI
Rnor_6.0	11	84,051,177 - 84,068,479 (-)	NCBI
Rnor_5.0	11	87,123,483 - 87,139,802 (-)	NCBI

Sequence:

show sequence

GGCCCAGAGCCGGGAGGGCCGAGGCCACCGGAAGAGTCGCGGTCGCCAGCCGAGCGCTGTGAGT
GGGGAGCGGAAGCGGTGGCGGGCGGCGCTGGGACCCGGGAGCGGCCGGAGAACAAGGGAGCTGG
CGCCCCGGCCGGCGGCTGAGCGGGGCTAAGCAGCGGGCCTCGCCGAGCGCCGAGCTCTGTCGGA
GAGGCCCGGCCCCGCTGCCCAAGCAGGCCGCACGCCGCGGGGCCGAGGCCGGAGCCATGGGCGA
GACTAAGATCATCTACCACTTGGACGGCCAGGAGACGCCGTACCTAGTGAAGCTGCCCCTGCCC
GCCGAGCGCGTCACCTTGGCGGACTTTAAGGGCGTTTTGCAGCGGCCCAGCTATAAGTTCTTCT
TCAAGTCTATGGACGACGATTTTGGAGTGGTGAAGGAAGAGATCTCGGATGACAATGCCAAGCT
GCCCTGCTTCAATGGCCGGGTGGTGTCCTGGCTGGTATCGGCCGAGGGCTCACACCCAGAGCCA
GCCCCTTTCTGTGCTGACAACCCCTCAGAGCTGCCTCCTTCAATGGAACGCACAGGAGGCATCG
GTGACTCTCGGCCCCCGTCCTTCCACCCTCATGCTAGTGGGGGCAGCCAGGAGAACTTGGACAA
TGACACAGAGACCGACTCCTTGGTATCTGCCCAACGAGAGCGGCCCAGACGGAGGGATGGCCCT
GAGCACGCCCGCCTCAATGGAACCACAAAGGGCGAGCGGCGACGGGAGCCAGGTGGCTATGACA
GTTCATCTACCCTCATGAGCAGCGAGCTGGAGACTACCAGTTTCTTTGATTCAGATGAGGATGA
CTCCACCAGCAGGTTCAGCAGCTCCACAGAACAGAGCAGTGCCTCACGCCTAATGAGAAGACAC
AAGCGGCGGCGACGGAAGCAGAAGGTCTCCCGGATTGAGCGGTCCTCCTCCTTCAGCAGCATCA
CAGACTCCACTATGTCTCTCAACATCATCACAGTGACTCTCAACATGGAAAAGTATAACTTCTT
GGGCATCTCCATTGTGGGCCAGAGCAATGAGCGAGGTGATGGGGGCATCTACATTGGCTCCATC
ATGAAGGGTGGGGCAGTGGCGGCTGATGGACGCATTGAGCCGGGAGATATGCTGTTGCAGGTAA
ATGAGATCAACTTCGAGAACATGAGTAATGATGACGCAGTCAGAGTGCTTCGGGAGATCGTGCA
CAAACCAGGGCCCATCACTCTGACTGTAGCCAAGTGCTGGGACCCAAGTCCTCGTGGCTGCTTC
ACATTACCCCGGAGTGAGCCCATCCGTCCCATTGACCCTGCAGCCTGGGTCTCCCACACTGCAG
CCATGACAGGAACCTTCCCTGCCTATGGCATGAGCCCCTCCTTAAGCACCATCACCTCCACCAG
CTCCTCCATCACCAGCTCCATCCCCGACACAGAACGCCTAGATGATTTCCACCTCTCCATCCAC
AGTGACATGGCGGCCATCGTAAAAGCCATGGCCTCCCCCGAGTCAGGGCTGGAGGTCCGAGACC
GCATGTGGCTCAAGATTACCATTCCCAATGCTTTCATCGGCTCAGATGTGGTGGACTGGCTGTA
TCACAATGTGGAAGGATTCACCGACCGGCGGGAGGCCCGCAAGTACGCTAGCAACCTGCTGAAG
GCTGGATTCATCCGCCACACGGTCAACAAGATCACGTTCTCTGAGCAGTGCTACTACATCTTTG
GTGACCTCTGTGGCAACATGGCCAACCTATCGCTGCACGACCATGATGGCTCCAGTGGTGCCTC
TGACCAGGACACACTGGCTCCTCTGCCGCACCCAGGGGCTGCCCCTTGGCCTATGGCTTTCCCT
TACCAGTACCCACCACCTCCGCACCCGTACAACCCACACCCAGGCTTCCCGGAGCTGGGCTACA
GCTACGCTGGGGGCAGCGCCAGCAGTCAGCACAGTGAAGGTAGTAGGAGCAGTGGCTCCAACCG
AAGTGGCAGCGACCGGCGCAAGGAGAAGGACCCAAAAGCTGGGGACTCAAAGTCAGGTGGTAGC
GGCAGCGAGTCAGACCACACTACACGCAGCAGTCTGCGGGGGCCACGGGAGCGGGCACCAAGCG
AGCGCTCAGGCCCAGCGGCCAGCGAGCACAGCCACCGCAGTCATCATTCACTGACCAGTAGCCT
GCGCAGCCACCACACACACCCAAGCTATGGCCCACCCGGAGTGCCCCCTCTCTATGGTCCCCCG
ATGCTGATGATGACCCCACCGCCTGCAGCCATGGGGCCCCCAGGAGCCCCTCCAGGGCGTGACC
TGGCCTCGGTGCCCCCGGAACTGACGGCCAGCAGACAGTCCTTCCGCATGGCAATGGGAAACCC
CACCAAGAATTTCGGGCTCTTTGACTTTCTGTGAGTCCCCAGGAAAGGGAGGCCCAGCCTCCAA
GGAGACCAGGAACTCTGCTTCAGCTCCCTCAGGGCTTCCCAAGGATGTCCAGCCCCCACAGGAC
CCACACTTCAAGGTCACTAGGCTTTTGGGAAGGGCCTCAGCTTCCCCCATGCATAACTGACTAC
TCTTTTCAGAGAGAAGTAGAGAAGTTCGCTCCCCTCCACCTCATACACATAGATATACATACAC
ATGTGAGTCTCTCCCCCCAACCCCTGGTCTCTGTCTCTCTGTCTCTGTCTCTGTCTCTCTCTCA
CGCCTATGCAAGTTTACAGAAGCCTCAGGGCTGGTCCCTGGCCAGAGGGCTGGACCCTTTTTCC
AAGTCATCTCCTAGATAGTAGGGCTGGTCCCTGACGTCCTCTTCCCTTCAGCTAGCCCTTAAGC
TTCCCTTACATGTTCCCAACATCTTTGTACTTAGATAAAAGTCCAAAAGCTGGGGCTCACCAGA
GGGCTCTCCGGTAACTGACAGATCATTCTCTACTTCCCTTCTGCCCCACATCTCTGGGTACCTG
CTCTGTTTCATCTTCCCCATGAACCCTGGGGACACAGGCCAGTTGAAGCTATACGAGCAGACAA
CTGGGGCTTCCAGACCGTTCCAGTTAACTGTTTTCTACCTTAAATCATAATTTCCTCCTTAAAA
CACCGCTATAAACTCTGACTTATCCAGACTCTTTAAATTTTCAGTCAAGGGTGTCAGCTGAGGA
AATAGCTGTGTAGTGCTTGCCTAGCATGCCCCAGCAAATGTCTCCCCCATCAAGATGTCCTTAG
CCCAGGTTTGGGGGCAACCTGAGGTAGGGATATTTTGACATTCATTTAACATATTTCCAGGGAC
TTTAATGAACAAAGGGCTATGTTAGAAGCATGACTTGATCTTCGCTGTCTTCAGTTCTCTCTGA
CTCTGCCTTTTCCTGTTCTCTTGAGAATCCCTCACCAGTGCTCCCATTATCCTGCCTTTGGCTC
ATGTCCCTTTCTTCCCCCCTTTCCCCCATAGTGTCAGCCACTCTCTTCTTAAGCTGTTGATGTG
CTGGCCACTTCTAAATCTGGATCTCCCACCCCAGCTTCCCCTCTCTTTAGATCTGTTTTTATTC
CCCACTGGACATCTCCCCAGGCTTGTCCATATGTCCCCAGCCAAGTATTATTCCTCTCGAATTC
CTGCCCTTGTGACCTTCATTACAAGCCACACCTACACGGGCTTAGTCAGCATCTCACACCCTTA
TACTCAGACACTCTGAAGTTCAGCTGTTCCTCTCCCTTCCTTACATTACAGAGCATGGGATTTG
GAGTCAGGTTGGTTTGGGCTTGATTTCCAGCTCTATCATTTTTGATTGTGTAATAGAGTTATTT
AACCTCTCTGGAGCCTCAGTCCTCCCATATGTAAAATGATGATAATAATACCTACCTCACAGGG
TTGTTGTGAGGATTTAAATTAGATATTGTACGAAAAGTGCCTAGCACAGTGCCTGGCACATAAT
AGAGTAGGTGCTCAATAAATGGTAGCTATTATTATTACTA

hide sequence

RefSeq Acc Id:

XM_006248566 ⟹ XP_006248628

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	11	84,051,177 - 84,068,479 (-)	NCBI
Rnor_5.0	11	87,123,483 - 87,139,802 (-)	NCBI

Sequence:

show sequence

GGCCCAGAGCCGGGAGGGCCGAGGCCACCGGAAGAGTCGCGGTCGCCAGCCGAGCGCTGTGAGT
GGGGAGCGGAAGCGGTGGCGGGCGGCGCTGGGACCCGGGAGCGGCCGGAGAACAAGGGAGCTGG
CGCCCCGGCCGGCGGCTGAGCGGGGCTAAGCAGCGGGCCTCGCCGAGCGCCGAGCTCTGTCGGA
GAGGCCCGGCCCCGCTGCCCAAGCAGGCCGCACGCCGCGGGGCCGAGGCCGGAGCCATGGGCGA
GACTAAGATCATCTACCACTTGGACGGCCAGGAGACGCCGTACCTAGTGAAGCTGCCCCTGCCC
GCCGAGCGCGTCACCTTGGCGGACTTTAAGGGCGTTTTGCAGCGGCCCAGCTATAAGTTCTTCT
TCAAGTCTATGGACGACGATTTTGGAGTGGTGAAGGAAGAGATCTCGGATGACAATGCCAAGCT
GCCCTGCTTCAATGGCCGGGTGGTGTCCTGGCTGGTATCGGCCGAGGGCTCACACCCAGAGCCA
GCCCCTTTCTGTGCTGACAACCCCTCAGAGCTGCCTCCTTCAATGGAACGCACAGGAGGCATCG
GTGACTCTCGGCCCCCGTCCTTCCACCCTCATGCTAGTGGGGGCAGCCAGGAGAACTTGGACAA
TGACACAGAGACCGACTCCTTGGTATCTGCCCAACGAGAGCGGCCCAGACGGAGGGATGGCCCT
GAGCACGCCCGCCTCAATGGAACCACAAAGGGCGAGCGGCGACGGGAGCCAGGTGGCTATGACA
GTTCATCTACCCTCATGAGCAGCGAGCTGGAGACTACCAGTTTCTTTGATTCAGATGAGGATGA
CTCCACCAGCAGGTTCAGCAGCTCCACAGAACAGAGCAGTGCCTCACGCCTAATGAGAAGACAC
AAGCGGCGGCGACGGAAGCAGAAGGTCTCCCGGATTGAGCGGTCCTCCTCCTTCAGCAGCATCA
CAGACTCCACTATGTCTCTCAACATCATCACAGTGACTCTCAACATGGAAAAGTATAACTTCTT
GGGCATCTCCATTGTGGGCCAGAGCAATGAGCGAGGTGATGGGGGCATCTACATTGGCTCCATC
ATGAAGGGTGGGGCAGTGGCGGCTGATGGACGCATTGAGCCGGGAGATATGCTGTTGCAGGTAA
ATGAGATCAACTTCGAGAACATGAGTAATGATGACGCAGTCAGAGTGCTTCGGGAGATCGTGCA
CAAACCAGGGCCCATCACTCTGACTGTAGCCAAGTGCTGGGACCCAAGTCCTCGTGGCTGCTTC
ACATTACCCCGGAGTGAGCCCATCCGTCCCATTGACCCTGCAGCCTGGGTCTCCCACACTGCAG
CCATGACAGGAACCTTCCCTGCCTATGGCATGAGCCCCTCCTTAAGCACCATCACCTCCACCAG
CTCCTCCATCACCAGCTCCATCCCCGACACAGAACGCCTAGATGATTTCCACCTCTCCATCCAC
AGTGACATGGCGGCCATCGTAAAAGCCATGGCCTCCCCCGAGTCAGGGCTGGAGGTCCGAGACC
GCATGTGGCTCAAGATTACCATTCCCAATGCTTTCATCGGCTCAGATGTGGTGGACTGGCTGTA
TCACAATGTGGAAGGATTCACCGACCGGCGGGAGGCCCGCAAGTACGCTAGCAACCTGCTGAAG
GCTGGATTCATCCGCCACACGGTCAACAAGATCACGTTCTCTGAGCAGTGCTACTACATCTTTG
GTGACCTCTGTGGCAACATGGCCAACCTATCGCTGCACGACCATGATGGCTCCAGTGGTGCCTC
TGACCAGGACACACTGGCTCCTCTGCCGCACCCAGGGGCTGCCCCTTGGCCTATGGCTTTCCCT
TACCAGTACCCACCACCTCCGCACCCGTACAACCCACACCCAGGCTTCCCGGAGCTGGGCTACA
GCTACGCTGGGGGCAGCGCCAGCAGTCAGCACAGTGAAGGTAGTAGGAGCAGTGGCTCCAACCG
AAGTGGCAGCGACCGGCGCAAGGAGAAGGACCCAAAAGCTGGGGACTCAAAGTCAGGTGGTAGC
GGCAGCGAGTCAGACCACACTACACGCAGCAGTCTGCGGGGGCCACGGGAGCGGGCACCAAGCG
AGCGCTCAGGCCCAGCGGCCAGCGAGCACAGCCACCGCAGTCATCATTCACTGACCAGTAGCCT
GCGCAGCCACCACACACACCCAAGCTATGGCCCACCCGGAGTGCCCCCTCTCTATGGTCCCCCG
ATGCTGATGATGACCCCACCGCCTGCAGCCATGGGGCCCCCAGGAGCCCCTCCAGGGCGTGACC
TGGCCTCGGTGCCCCCGGAACTGACGGCCAGCAGACAGTCCTTCCGCATGGCAATGGGAAACCC
CAGTGAGTTCTTTGTGGATGTGATGTGATCCGGGCCCCTCTCCAGCTCTCACCCCTCAGCCGGC
TGCACCCCCATCTCAGTCGGCCTTTTTTTTTTTTAAACTTTGGTACCTGAAAGGGAAATAAATG
GAACTAACTGCTACTGCTTGCTGGTAGCAGCAAGGATGAGAAGTCTTTACTCATCCATGCTTCA
GCCCCTAACCTGCCTCTAGCCCAGCTGGTGCCTCTGTCCACTAACCATCCCCATTCCACCCAGT
TCCGGGCTTCCCAGGGTTTTTCATGTCCCTGCCTCTGCACTGCTAGTGTTAATTCCTGATGCTC
CTCCACCCGCACGTTTAGGAGCTAACCCCAGCAGTGCCACATCTTATGCCCACCTTCCCTCCTC
GGTACCCTTTTGCCCACCTCCGTAAGCATGTGTACAGAGATCAGGATATTGCCCCACCATACTG
ACACCAAAAAATGGTCTTTCCCTTCCTAACTGGCCTGCCCGCTGCTTCAGACCTTCACCCTACA
GCTGTAGCCACCTCTAGTAGGCATCTGTGCTGTCTGTCCCTGCTTGGACCCAGCCCCAATCAGA
AGCCCAGAGAGCCATCCTGCCCCTCCCCCCCCACAGGTGCCTGGGCCCCATCCATGCCTGCCCT
GTGCTCTGGTTCCCCGAGATCTAACCCTACTAACCAATAGGCTCTCCTAACTTCTGAGCCTGAA
ACATTTCTCTTCTTTTTTTCTTCCTTCAAATTTCCCTGGGTCTGGAGCAGCCAAGAATTTCGGG
CTCTTTGACTTTCTGTGAGTCCCCAGGAAAGGGAGGCCCAGCCTCCAAGGAGACCAGGAACTCT
GCTTCAGCTCCCTCAGGGCTTCCCAAGGATGTCCAGCCCCCACAGGACCCACACTTCAAGGTCA
CTAGGCTTTTGGGAAGGGCCTCAGCTTCCCCCATGCATAACTGACTACTCTTTTCAGAGAGAAG
TAGAGAAGTTCGCTCCCCTCCACCTCATACACATAGATATACATACACATGTGAGTCTCTCCCC
CCAACCCCTGGTCTCTGTCTCTCTGTCTCTGTCTCTGTCTCTCTCTCACGCCTATGCAAGTTTA
CAGAAGCCTCAGGGCTGGTCCCTGGCCAGAGGGCTGGACCCTTTTTCCAAGTCATCTCCTAGAT
AGTAGGGCTGGTCCCTGACGTCCTCTTCCCTTCAGCTAGCCCTTAAGCTTCCCTTACATGTTCC
CAACATCTTTGTACTTAGATAAAAGTCCAAAAGCTGGGGCTCACCAGAGGGCTCTCCGGTAACT
GACAGATCATTCTCTACTTCCCTTCTGCCCCACATCTCTGGGTACCTGCTCTGTTTCATCTTCC
CCATGAACCCTGGGGACACAGGCCAGTTGAAGCTATACGAGCAGACAACTGGGGCTTCCAGACC
GTTCCAGTTAACTGTTTTCTACCTTAAATCATAATTTCCTCCTTAAAACACCGCTATAAACTCT
GACTTATCCAGACTCTTTAAATTTTCAGTCAAGGGTGTCAGCTGAGGAAATAGCTGTGTAGTGC
TTGCCTAGCATGCCCCAGCAAATGTCTCCCCCATCAAGATGTCCTTAGCCCAGGTTTGGGGGCA
ACCTGAGGTAGGGATATTTTGACATTCATTTAACATATTTCCAGGGACTTTAATGAACAAAGGG
CTATGTTAGAAGCATGACTTGATCTTCGCTGTCTTCAGTTCTCTCTGACTCTGCCTTTTCCTGT
TCTCTTGAGAATCCCTCACCAGTGCTCCCATTATCCTGCCTTTGGCTCATGTCCCTTTCTTCCC
CCCTTTCCCCCATAGTGTCAGCCACTCTCTTCTTAAGCTGTTGATGTGCTGGCCACTTCTAAAT
CTGGATCTCCCACCCCAGCTTCCCCTCTCTTTAGATCTGTTTTTATTCCCCACTGGACATCTCC
CCAGGCTTGTCCATATGTCCCCAGCCAAGTATTATTCCTCTCGAATTCCTGCCCTTGTGACCTT
CATTACAAGCCACACCTACACGGGCTTAGTCAGCATCTCACACCCTTATACTCAGACACTCTGA
AGTTCAGCTGTTCCTCTCCCTTCCTTACATTACAGAGCATGGGATTTGGAGTCAGGTTGGTTTG
GGCTTGATTTCCAGCTCTATCATTTTTGATTGTGTAATAGAGTTATTTAACCTCTCTGGAGCCT
CAGTCCTCCCATATGTAAAATGATGATAATAATACCTACCTCACAGGGTTGTTGTGAGGATTTA
AATTAGATATTGTACGAAAAGTGCCTAGCACAGTGCCTGGCACATAATAGAGTAGGTGCTCAAT
AAATGGTAGCTATTATTATTACTA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001100551	(Get FASTA)	NCBI Sequence Viewer
	XP_006248626	(Get FASTA)	NCBI Sequence Viewer
	XP_006248627	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDL77996	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:

NP_001100551 ⟸ NM_001107081

- Sequence:

show sequence

MDDDFGVVKEEISDDNAKLPCFNGRVVSWLVSAEGSHPEPAPFCADNPSELPPSMERTGGIGDS
RPPSFHPHASGGSQENLDNDTETDSLVSAQRERPRRRDGPEHAARLNGTTKGERRREPGGYDSS
STLMSSELETTSFFDSDEDDSTSRFSSSTEQSSASRLMRRHKRRRRKQKVSRIERSSSFSSITD
STMSLNIITVTLNMEKYNFLGISIVGQSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNE
INFENMSNDDAVRVLREIVHKPGPITLTVAKCWDPSPRGCFTLPRSEPIRPIDPAAWVSHTAAM
TGTFPAYGMSPSLSTITSTSSSITSSIPDTERLDDFHLSIHSDMAAIVKAMASPESGLEVRDRM
WLKITIPNAFIGSDVVDWLYHNVEGFTDRREARKYASNLLKAGFIRHTVNKITFSEQCYYIFGD
LCGNMANLSLHDHDGSSGASDQDTLAPLPHPGAAPWPMAFPYQYPPPPHPYNPHPGFPELGYSY
AGGSASSQHSEGSRSSGSNRSGSDRRKEKDPKAGDSKSGGSGSESDHTTRSSLRGPRERAPSER
SGPAASEHSHRSHHSLTSSLRSHHTHPSYGPPGVPPLYGPPMLMMTPPPAAMGPPGAPPGRDLA
SVPPELTASRQSFRMAMGNPSEFFVDVM

hide sequence

RefSeq Acc Id:

XP_006248627 ⟸ XM_006248565

- Peptide Label:

isoform X2

- Sequence:

show sequence

MGETKIIYHLDGQETPYLVKLPLPAERVTLADFKGVLQRPSYKFFFKSMDDDFGVVKEEISDDN
AKLPCFNGRVVSWLVSAEGSHPEPAPFCADNPSELPPSMERTGGIGDSRPPSFHPHASGGSQEN
LDNDTETDSLVSAQRERPRRRDGPEHARLNGTTKGERRREPGGYDSSSTLMSSELETTSFFDSD
EDDSTSRFSSSTEQSSASRLMRRHKRRRRKQKVSRIERSSSFSSITDSTMSLNIITVTLNMEKY
NFLGISIVGQSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNEINFENMSNDDAVRVLRE
IVHKPGPITLTVAKCWDPSPRGCFTLPRSEPIRPIDPAAWVSHTAAMTGTFPAYGMSPSLSTIT
STSSSITSSIPDTERLDDFHLSIHSDMAAIVKAMASPESGLEVRDRMWLKITIPNAFIGSDVVD
WLYHNVEGFTDRREARKYASNLLKAGFIRHTVNKITFSEQCYYIFGDLCGNMANLSLHDHDGSS
GASDQDTLAPLPHPGAAPWPMAFPYQYPPPPHPYNPHPGFPELGYSYAGGSASSQHSEGSRSSG
SNRSGSDRRKEKDPKAGDSKSGGSGSESDHTTRSSLRGPRERAPSERSGPAASEHSHRSHHSLT
SSLRSHHTHPSYGPPGVPPLYGPPMLMMTPPPAAMGPPGAPPGRDLASVPPELTASRQSFRMAM
GNPTKNFGLFDFL

hide sequence

RefSeq Acc Id:

XP_006248628 ⟸ XM_006248566

- Peptide Label:

isoform X3

- Sequence:

show sequence

MGETKIIYHLDGQETPYLVKLPLPAERVTLADFKGVLQRPSYKFFFKSMDDDFGVVKEEISDDN
AKLPCFNGRVVSWLVSAEGSHPEPAPFCADNPSELPPSMERTGGIGDSRPPSFHPHASGGSQEN
LDNDTETDSLVSAQRERPRRRDGPEHARLNGTTKGERRREPGGYDSSSTLMSSELETTSFFDSD
EDDSTSRFSSSTEQSSASRLMRRHKRRRRKQKVSRIERSSSFSSITDSTMSLNIITVTLNMEKY
NFLGISIVGQSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNEINFENMSNDDAVRVLRE
IVHKPGPITLTVAKCWDPSPRGCFTLPRSEPIRPIDPAAWVSHTAAMTGTFPAYGMSPSLSTIT
STSSSITSSIPDTERLDDFHLSIHSDMAAIVKAMASPESGLEVRDRMWLKITIPNAFIGSDVVD
WLYHNVEGFTDRREARKYASNLLKAGFIRHTVNKITFSEQCYYIFGDLCGNMANLSLHDHDGSS
GASDQDTLAPLPHPGAAPWPMAFPYQYPPPPHPYNPHPGFPELGYSYAGGSASSQHSEGSRSSG
SNRSGSDRRKEKDPKAGDSKSGGSGSESDHTTRSSLRGPRERAPSERSGPAASEHSHRSHHSLT
SSLRSHHTHPSYGPPGVPPLYGPPMLMMTPPPAAMGPPGAPPGRDLASVPPELTASRQSFRMAM
GNPSEFFVDVM

hide sequence

RefSeq Acc Id:

XP_006248626 ⟸ XM_006248564

- Peptide Label:

isoform X1

- Sequence:

show sequence

MGETKIIYHLDGQETPYLVKLPLPAERVTLADFKGVLQRPSYKFFFKSMDDDFGVVKEEISDDN
AKLPCFNGRVVSWLVSAEGSHPEPAPFCADNPSELPPSMERTGGIGDSRPPSFHPHASGGSQEN
LDNDTETDSLVSAQRERPRRRDGPEHAARLNGTTKGERRREPGGYDSSSTLMSSELETTSFFDS
DEDDSTSRFSSSTEQSSASRLMRRHKRRRRKQKVSRIERSSSFSSITDSTMSLNIITVTLNMEK
YNFLGISIVGQSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNEINFENMSNDDAVRVLR
EIVHKPGPITLTVAKCWDPSPRGCFTLPRSEPIRPIDPAAWVSHTAAMTGTFPAYGMSPSLSTI
TSTSSSITSSIPDTERLDDFHLSIHSDMAAIVKAMASPESGLEVRDRMWLKITIPNAFIGSDVV
DWLYHNVEGFTDRREARKYASNLLKAGFIRHTVNKITFSEQCYYIFGDLCGNMANLSLHDHDGS
SGASDQDTLAPLPHPGAAPWPMAFPYQYPPPPHPYNPHPGFPELGYSYAGGSASSQHSEGSRSS
GSNRSGSDRRKEKDPKAGDSKSGGSGSESDHTTRSSLRGPRERAPSERSGPAASEHSHRSHHSL
TSSLRSHHTHPSYGPPGVPPLYGPPMLMMTPPPAAMGPPGAPPGRDLASVPPELTASRQSFRMA
MGNPTKNFGLFDFL

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RefSeq Acc Id:

ENSRNOP00000002323 ⟸ ENSRNOT00000002323

Protein Domains

DEP DIX PDZ

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13698280

Promoter ID:

EPDNEW_R8804

Type:

initiation region

Name:

Dvl3_1

Description:

dishevelled segment polarity protein 3

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	11	84,068,362 - 84,068,422	EPDNEW

Strain Variation

Strain Sequence Variants (Rnor 6.0)

ACI/EurMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

ACI/EurMcwi (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

ACI/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

BBDP/Wor (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

BN/SsN (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Buf/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

COP/CrCrl (MCW & UW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob) University of Wisconsin (Dr. James Shull)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Charles River Laboratories
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)

F344/NCrl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

F344/NRrrc (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

FHH/EurMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

FHH/EurMcwi (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

FHL/EurMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

FHL/EurMcwi (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

GH/OmrMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

GK/Ox (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LE/Stm (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LEW/Crl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LEW/NCrlBR (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LH/MavRrrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LL/MavRrrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LN/MavRrrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

M520/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

MHS/Gib (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

MNS/Gib (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

MR/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

SBH/Ygl (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	SBH/Ygl sequenced by MCW

SBH/Ygl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SBN/Ygl (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	SBN/Ygl sequenced by MCW

SBN/Ygl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SHR/NHsd (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SHRSP/Gcrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SR/JrHsd (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Harlan Laboratories
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

SR/JrHsd (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SS/Jr (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SS/JrHsdMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

SS/JrHsdMcwi (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WAG/Rij (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/Gcrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

WKY/NCrl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/NHsd (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WN/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1308834	AgrOrtholog
Ensembl Genes	ENSRNOG00000001708	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein	ENSRNOP00000002323	ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000002323	ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH	1.10.10.10	UniProtKB/TrEMBL
	2.30.42.10	UniProtKB/TrEMBL
	3.10.20.380	UniProtKB/TrEMBL
InterPro	DEP_dom	UniProtKB/TrEMBL
	Dishevell	UniProtKB/TrEMBL
	Dishevelled_3	UniProtKB/TrEMBL
	Dishevelled_C-dom	UniProtKB/TrEMBL
	Dishevelled_protein	UniProtKB/TrEMBL
	DIX	UniProtKB/TrEMBL
	DIX_dom_sf	UniProtKB/TrEMBL
	Dsh	UniProtKB/TrEMBL
	PDZ/DHR/GLGF	UniProtKB/TrEMBL
	PDZ_sf	UniProtKB/TrEMBL
	Ubiquitin-rel_dom	UniProtKB/TrEMBL
	WH-like_DNA-bd_sf	UniProtKB/TrEMBL
	WH_DNA-bd_sf	UniProtKB/TrEMBL
NCBI Gene	303811	ENTREZGENE
PANTHER	Dsh	UniProtKB/TrEMBL
	PTHR10878:SF6	UniProtKB/TrEMBL
Pfam	DEP	UniProtKB/TrEMBL
	Dishevelled	UniProtKB/TrEMBL
	DIX	UniProtKB/TrEMBL
	Dsh_C	UniProtKB/TrEMBL
	PDZ	UniProtKB/TrEMBL
PhenoGen	Dvl3	PhenoGen
PRINTS	DISHEVELLED	UniProtKB/TrEMBL
	DISHEVELLED3	UniProtKB/TrEMBL
PROSITE	DEP	UniProtKB/TrEMBL
	DIX	UniProtKB/TrEMBL
	PDZ	UniProtKB/TrEMBL
SMART	DAX	UniProtKB/TrEMBL
	DEP	UniProtKB/TrEMBL
	PDZ	UniProtKB/TrEMBL
Superfamily-SCOP	PDZ	UniProtKB/TrEMBL
	SSF46785	UniProtKB/TrEMBL
	SSF54236	UniProtKB/TrEMBL
UniProt	D4ADV8_RAT	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2013-06-05	Dvl3	dishevelled segment polarity protein 3	Dvl3	dishevelled, dsh homolog 3 (Drosophila)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-09-24	Dvl3	dishevelled, dsh homolog 3 (Drosophila)	Dvl3	dishevelled 3, dsh homolog (Drosophila)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-04-30	Dvl3	dishevelled 3, dsh homolog (Drosophila)	Dvl3_predicted	dishevelled 3, dsh homolog (Drosophila) (predicted)	'predicted' is removed	2292626	APPROVED
2005-01-12	Dvl3_predicted	dishevelled 3, dsh homolog (Drosophila) (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - KEGG (archival)

Imported Annotations - PID (archival)

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - KEGG (archival)

Imported Annotations - PID (archival)