Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Egr2 (early growth response 2) Rattus norvegicus
Analyze
Symbol: Egr2
Name: early growth response 2
Description: Exhibits HMG box domain binding activity. Involved in learning or memory; regulation of neuronal synaptic plasticity; and response to insulin. Predicted to localize to the cytoplasm and nucleoplasm. Biomarker of middle cerebral artery infarction. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease type 1D; Charcot-Marie-Tooth disease type 3; Charcot-Marie-Tooth disease type 4E; and motor peripheral neuropathy. Orthologous to human EGR2 (early growth response 2); PARTICIPATES IN interleukin-4 signaling pathway; INTERACTS WITH (+)-pilocarpine; 1,2-dimethylhydrazine; 3alpha-hydroxy-5beta-pregnan-20-one.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: E3 SUMO-protein ligase EGR2; E3 SUMO-protein transferase ERG2; early growth response protein 2; EGR-2; Krox20; zinc finger protein Krox-20
Orthologs:
Homo sapiens (human) : EGR2 (early growth response 2)  HGNC  Alliance
Mus musculus (house mouse) : Egr2 (early growth response 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Egr2 (early growth response 2)
Pan paniscus (bonobo/pygmy chimpanzee) : EGR2 (early growth response 2)
Canis lupus familiaris (dog) : EGR2 (early growth response 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Egr2 (early growth response 2)
Sus scrofa (pig) : EGR2 (early growth response 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.02022,452,170 - 22,461,018 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2022,454,463 - 22,459,025 (-)Ensembl
Rnor_5.02024,551,935 - 24,556,227 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42021,883,885 - 21,888,177 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12021,897,685 - 21,901,977 (-)NCBI
Celera2022,412,625 - 22,416,917 (-)NCBICelera
Cytogenetic Map20p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Egr2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 621608
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-10-16
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.