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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3831
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Zeb1
Name: zinc finger E-box binding homeobox 1
Acc ID: CHEBI:27617
Term: monensin A
Definition: A spiroketal, monensin A is the major component of monensin, a mixture of antibiotic substances produced by Streptomyces cinnamonensis. An antiprotozoal, it is used as the sodium salt as a feed additive for the prevention of coccidiosis in poultry and as a growth promoter in cattle.
Chemical ID: MESH:D008985
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Zeb1increases response to substanceISORGD:12999536480464CTDZEB1 protein results in increased susceptibility to Monensin

PMID:30718715
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.