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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1311889
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Trpm2
Name: transient receptor potential cation channel, subfamily M, member 2
Acc ID: CHEBI:27617
Term: monensin A
Definition: A spiroketal, monensin A is the major component of monensin, a mixture of antibiotic substances produced by Streptomyces cinnamonensis. An antiprotozoal, it is used as the sodium salt as a feed additive for the prevention of coccidiosis in poultry and as a growth promoter in cattle.
Chemical ID: MESH:D008985
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Trpm2decreases expressionISORGD:13235826480464CTDMonensin results in decreased expression of TRPM2 protein alternative form

PMID:20799912
Trpm2increases expressionISORGD:13235826480464CTDMonensin results in increased expression of TRPM2 protein alternative form

PMID:20799912
Trpm2multiple interactionsISORGD:13235826480464CTDLithium inhibits the reaction [Monensin results in increased expression of TRPM2 protein alternative form]

PMID:20799912
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