Gene: Abl1 (ABL proto-oncogene 1, non-receptor tyrosine kinase) Rattus norvegicus
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Symbol: Abl1
Name: ABL proto-oncogene 1, non-receptor tyrosine kinase
Description: Exhibits delta-catenin binding activity, protein kinase activity, and protein kinase binding activity; involved in several processes, including actin filament polymerization, positive regulation of cell death, and positive regulation of cellular component organization; localizes to several cellular components, including the intracellular membrane-bounded organelle, neuron projection, and neuronal cell body; biomarker of Parkinson's disease and ureteral obstruction; orthologous to human ABL1 (ABL proto-oncogene 1, non-receptor tyrosine kinase); PARTICIPATES IN p53 signaling pathway; platelet-derived growth factor signaling pathway; cell cycle pathway, mitotic; INTERACTS WITH 1,2-dimethylhydrazine; 3,3',5,5'-tetrabromobisphenol A; ammonium chloride.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Abelson murine leukemia viral (v-abl) oncogene homolog 1; Abl; Abl1_mapped; c-abl oncogene 1, non-receptor tyrosine kinase; c-abl oncogene 1, receptor tyrosine kinase; tyrosine-protein kinase ABL1; v-abl Abelson murine leukemia viral oncogene 1; v-abl Abelson murine leukemia viral oncogene homolog 1; v-abl Abelson murine leukemia viral oncogene homolog 1 (mapped)
Orthologs:
Homo sapiens (human) : ABL1 (ABL proto-oncogene 1, non-receptor tyrosine kinase)  HGNC  Alliance
Mus musculus (house mouse) : Abl1 (c-abl oncogene 1, non-receptor tyrosine kinase)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Abl1 (ABL proto-oncogene 1, non-receptor tyrosine kinase)
Pan paniscus (bonobo/pygmy chimpanzee) : ABL1 (ABL proto-oncogene 1, non-receptor tyrosine kinase)
Canis lupus familiaris (dog) : ABL1 (ABL proto-oncogene 1, non-receptor tyrosine kinase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Abl1 (ABL proto-oncogene 1, non-receptor tyrosine kinase)
Sus scrofa (pig) : ABL1 (ABL proto-oncogene 1, non-receptor tyrosine kinase)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0310,041,820 - 10,145,076 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0315,401,182 - 15,504,438 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4310,804,594 - 10,907,162NCBIRGSC3.4rn4RGSC3.4
Cytogenetic Map3p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model

Annotation    (Toggle Annotation Detail/Summary View)

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References - curated
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RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
  
More on Abl1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1584969
Created: 2006-11-19
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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