Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Abl1 (ABL proto-oncogene 1, non-receptor tyrosine kinase) Rattus norvegicus
Symbol: Abl1
Name: ABL proto-oncogene 1, non-receptor tyrosine kinase
Description: Exhibits delta-catenin binding activity; protein kinase activity; and protein kinase binding activity. Involved in several processes, including glomerular visceral epithelial cell apoptotic process; positive regulation of cellular component organization; and positive regulation of programmed cell death. Localizes to several cellular components, including growth cone; neuronal cell body; and ruffle. Biomarker of Parkinson's disease and ureteral obstruction. Human ortholog(s) of this gene implicated in B-lymphoblastic leukemia/lymphoma; acute myeloid leukemia; and chronic myeloid leukemia. Orthologous to human ABL1 (ABL proto-oncogene 1, non-receptor tyrosine kinase); PARTICIPATES IN p53 signaling pathway; platelet-derived growth factor signaling pathway; cell cycle pathway, mitotic; INTERACTS WITH 1,2-dimethylhydrazine; 3,3',5,5'-tetrabromobisphenol A; ammonium chloride.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Abelson murine leukemia viral (v-abl) oncogene homolog 1; Abl; Abl1_mapped; c-abl oncogene 1, non-receptor tyrosine kinase; c-abl oncogene 1, receptor tyrosine kinase; tyrosine-protein kinase ABL1; v-abl Abelson murine leukemia viral oncogene 1; v-abl Abelson murine leukemia viral oncogene homolog 1; v-abl Abelson murine leukemia viral oncogene homolog 1 (mapped)
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0310,041,820 - 10,145,076 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl310,041,826 - 10,144,388 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0315,401,182 - 15,504,438 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4310,804,594 - 10,907,162NCBIRGSC3.4rn4RGSC3.4
Cytogenetic Map3p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Abl1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1584969
Created: 2006-11-19
Species: Rattus norvegicus
Last Modified: 2020-07-28
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.