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Gene: Plaa (phospholipase A2, activating protein) Rattus norvegicus
Symbol: Plaa
Name: phospholipase A2, activating protein
Description: Predicted to have phospholipase A2 activator activity and ubiquitin binding activity. Predicted to be involved in several processes, including negative regulation of protein K63-linked ubiquitination; positive regulation of neurogenesis; and ubiquitin-dependent protein catabolic process. Predicted to localize to several cellular components, including extracellular exosome; nucleus; and synapse. Orthologous to human PLAA (phospholipase A2 activating protein); PARTICIPATES IN Endoplasmic Reticulum-associated degradation pathway; INTERACTS WITH (+)-schisandrin B; 2,6-dinitrotoluene; 3H-1,2-dithiole-3-thione.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: phospholipase A-2-activating protein; PLA2P; Plap
Homo sapiens (human) : PLAA (phospholipase A2 activating protein)  HGNC  Alliance
Mus musculus (house mouse) : Plaa (phospholipase A2, activating protein)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Plaa (phospholipase A2 activating protein)
Pan paniscus (bonobo/pygmy chimpanzee) : PLAA (phospholipase A2 activating protein)
Canis lupus familiaris (dog) : PLAA (phospholipase A2 activating protein)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Plaa (phospholipase A2 activating protein)
Sus scrofa (pig) : PLAA (phospholipase A2 activating protein)
Chlorocebus sabaeus (African green monkey) : PLAA (phospholipase A2 activating protein)
Heterocephalus glaber (naked mole-rat) : Plaa (phospholipase A2 activating protein)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.05113,548,913 - 113,578,928 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5113,548,913 - 113,578,928 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05117,491,921 - 117,523,644 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45114,869,341 - 114,899,356 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.15114,874,675 - 114,904,441 (-)NCBI
Celera5108,057,280 - 108,087,304 (-)NCBICelera
Cytogenetic Map5q33NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Plaa
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 621245
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.