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Imported Disease Annotations - ClinVarTerm | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | megacolon | | ISO | RGD:732380 | 8554872 | ClinVar Annotator: match by term: Megacolon | ClinVar | PMID:21681106 | |
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Imported Disease Annotations - ClinVarTerm | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | megacolon | | ISO | RGD:732380 | 8554872 | ClinVar Annotator: match by term: Megacolon | ClinVar | PMID:21681106 | |
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# | Reference Title | Reference Citation |
1. | Functional consequences of thyroid hormone-induced changes in the mitochondrial protein import pathway. | Colavecchia M, etal., Am J Physiol Endocrinol Metab. 2003 Jan;284(1):E29-35. doi: 10.1152/ajpendo.00294.2002. Epub 2002 Sep 17. |
2. | Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. | Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27. |
3. | Rat ISS GO annotations from GOA human gene data--August 2006 | GOA data from the GO Consortium |
4. | Identification of the protein import components of the rat mitochondrial inner membrane, rTIM17, rTIM23, and rTIM44. | Ishihara N and Mihara K, J Biochem (Tokyo) 1998 Apr;123(4):722-32. |
5. | Characterization of the initial steps of precursor import into rat liver mitoplasts. | Ishihara N, etal., J Biochem. 1998 Oct;124(4):824-34. |
6. | Rat ISS GO annotations from MGI mouse gene data--August 2006 | MGD data from the GO Consortium |
7. | Electronic Transfer of LocusLink and RefSeq Data | NCBI rat LocusLink and RefSeq merged data July 26, 2002 |
8. | GOA pipeline | RGD automated data pipeline |
9. | Data Import for Chemical-Gene Interactions | RGD automated import pipeline for gene-chemical interactions |
10. | Unlocking the presequence import pathway. | Schulz C, etal., Trends Cell Biol. 2015 May;25(5):265-75. doi: 10.1016/j.tcb.2014.12.001. Epub 2014 Dec 23. |
11. | Effect of denervation-induced muscle disuse on mitochondrial protein import. | Singh K and Hood DA, Am J Physiol Cell Physiol. 2011 Jan;300(1):C138-45. doi: 10.1152/ajpcell.00181.2010. Epub 2010 Oct 13. |
12. | Tentative Sequence Identification Numbers | Tentative Sequence Data IDs. TIGR Gene Index, Rat Data |
13. | Cooperation of protein machineries in mitochondrial protein sorting. | Wenz LS, etal., Biochim Biophys Acta. 2015 May;1853(5):1119-29. doi: 10.1016/j.bbamcr.2015.01.012. Epub 2015 Jan 26. |
PMID:10339406 | PMID:12477932 | PMID:12865426 | PMID:14651853 | PMID:15044455 | PMID:17035996 | PMID:18614015 | PMID:20053669 | PMID:25997101 |
Timm23 (Rattus norvegicus - Norway rat) |
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TIMM23 (Homo sapiens - human) |
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TIMM23 (Homo sapiens - human) |
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Timm23 (Mus musculus - house mouse) |
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TIMM23 (Pan paniscus - bonobo/pygmy chimpanzee) |
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LOC486776 (Canis lupus familiaris - dog) |
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LOC100157391 (Sus scrofa - pig) |
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Variants in Timm23
135 total Variants ![]() |
The detailed report is available here: | ![]() | Full Report | ![]() | CSV | ![]() | TAB | ![]() | Printer |
miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/). For more information about miRGate, see PMID:25858286 or access the full paper here. |
The following QTLs overlap with this region. | ![]() | Full Report | ![]() | CSV | ![]() | TAB | ![]() | Printer | ![]() | Gviewer |
AI010983 |
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alimentary part of gastrointestinal system | circulatory system | endocrine system | exocrine system | hemolymphoid system | hepatobiliary system | integumental system | musculoskeletal system | nervous system | renal system | reproductive system | respiratory system | appendage | |
High | |||||||||||||
Medium | 3 | 43 | 57 | 41 | 19 | 41 | 8 | 11 | 74 | 35 | 41 | 11 | 8 |
Low | |||||||||||||
Below cutoff |
RefSeq Transcripts | NM_019352 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
XM_039094791 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
GenBank Nucleotide | AB006451 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
AC129637 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
BC058477 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
BC083559 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
FQ215721 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
FQ216304 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
FQ216447 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
FQ229692 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
FQ229803 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
FQ234059 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
JACYVU010000273 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
RefSeq Acc Id: | NM_019352 ⟹ NP_062225 | ||||||||||||||||||||||||
RefSeq Status: | PROVISIONAL | ||||||||||||||||||||||||
Type: | CODING | ||||||||||||||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XM_039094791 ⟹ XP_038950719 | ||||||||
RefSeq Status: | |||||||||
Type: | CODING | ||||||||
Position: |
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Protein RefSeqs | NP_062225 | (Get FASTA) | NCBI Sequence Viewer |
XP_038950719 | (Get FASTA) | NCBI Sequence Viewer | |
GenBank Protein | AAH83559 | (Get FASTA) | NCBI Sequence Viewer |
BAA21819 | (Get FASTA) | NCBI Sequence Viewer | |
O35093 | (Get FASTA) | NCBI Sequence Viewer |
RefSeq Acc Id: | NP_062225 ⟸ NM_019352 |
- UniProtKB: | O35093 (UniProtKB/Swiss-Prot) |
- Sequence: |
RefSeq Acc Id: | XP_038950719 ⟸ XM_039094791 |
- Peptide Label: | isoform X1 |
Name | Modeler | Protein Id | AA Range | Protein Structure |
AF-O35093-F1-model_v2 | AlphaFold | O35093 | 1-209 | view protein structure |
eQTL | View at Phenogen | |
WGCNA | View at Phenogen | |
Tissue/Strain Expression | View at Phenogen |
RGD ID: | 13699940 | ||||||||
Promoter ID: | EPDNEW_R10463 | ||||||||
Type: | initiation region | ||||||||
Name: | Timm23_1 | ||||||||
Description: | translocase of inner mitochondrial membrane 23 | ||||||||
SO ACC ID: | SO:0000170 | ||||||||
Source: | EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/) | ||||||||
Experiment Methods: | Single-end sequencing. | ||||||||
Position: |
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Database | Acc Id | Source(s) |
AGR Gene | RGD:3863 | AgrOrtholog |
BioCyc Gene | G2FUF-12116 | BioCyc |
Ensembl Genes | ENSRNOG00000019811 | Ensembl, ENTREZGENE, UniProtKB/TrEMBL |
Ensembl Protein | ENSRNOP00000026932 | ENTREZGENE |
ENSRNOP00000095080.1 | UniProtKB/TrEMBL | |
Ensembl Transcript | ENSRNOT00000026932 | ENTREZGENE |
ENSRNOT00000095039.1 | UniProtKB/TrEMBL | |
IMAGE_CLONE | IMAGE:7135081 | IMAGE-MGC_LOAD |
InterPro | Tim23 | UniProtKB/Swiss-Prot |
Tim23-like | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
KEGG Report | rno:54312 | UniProtKB/Swiss-Prot |
MGC_CLONE | MGC:93478 | IMAGE-MGC_LOAD |
NCBI Gene | 54312 | ENTREZGENE |
PANTHER | PTHR15371 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
PhenoGen | Timm23 | PhenoGen |
TIGR | TC204523 | |
TIGRFAMs | 3a0801s02tim23 | UniProtKB/Swiss-Prot |
UniProt | A0A8I6AMB8_RAT | UniProtKB/TrEMBL |
O35093 | ENTREZGENE, UniProtKB/Swiss-Prot |
Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
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2016-03-15 | Timm23 | translocase of inner mitochondrial membrane 23 | Timm23 | translocase of inner mitochondrial membrane 23 homolog (yeast) | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
2002-06-10 | Timm23 | translocase of inner mitochondrial membrane 23 homolog (yeast) | Name updated | 70584 | APPROVED |