Bltp3a (bridge-like lipid transfer protein family member 3A) - Rat Genome Database

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Gene: Bltp3a (bridge-like lipid transfer protein family member 3A) Rattus norvegicus
Analyze
Symbol: Bltp3a
Name: bridge-like lipid transfer protein family member 3A
RGD ID: 1307264
Description: Predicted to enable histone deacetylase binding activity and identical protein binding activity. Predicted to be located in late endosome. Orthologous to human BLTP3A (bridge-like lipid transfer protein family member 3A); INTERACTS WITH bisphenol A; Brodifacoum; paracetamol.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC309637; RGD1307264; similar to CG31653-PA; similar to hypothetical protein FLJ20302; UHRF1 binding protein 1; UHRF1-binding protein 1; Uhrf1bp1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8205,912,033 - 5,956,404 (+)NCBIGRCr8
mRatBN7.2205,910,261 - 5,954,641 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl205,910,260 - 5,952,404 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.0207,431,235 - 7,475,515 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl207,431,355 - 7,471,900 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0209,633,259 - 9,677,553 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4206,067,567 - 6,108,468 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1206,067,004 - 6,110,533 (+)NCBI
Celera207,471,148 - 7,515,710 (+)NCBICelera
Cytogenetic Map20p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:15361834  


Genomics

Comparative Map Data
Bltp3a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8205,912,033 - 5,956,404 (+)NCBIGRCr8
mRatBN7.2205,910,261 - 5,954,641 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl205,910,260 - 5,952,404 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.0207,431,235 - 7,475,515 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl207,431,355 - 7,471,900 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0209,633,259 - 9,677,553 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4206,067,567 - 6,108,468 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1206,067,004 - 6,110,533 (+)NCBI
Celera207,471,148 - 7,515,710 (+)NCBICelera
Cytogenetic Map20p12NCBI
BLTP3A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38634,792,083 - 34,877,514 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl634,792,083 - 34,877,514 (+)EnsemblGRCh38hg38GRCh38
GRCh37634,759,860 - 34,845,291 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36634,867,772 - 34,953,269 (+)NCBINCBI36Build 36hg18NCBI36
Build 34634,867,772 - 34,961,095NCBI
Celera636,314,255 - 36,399,721 (+)NCBICelera
Cytogenetic Map6p21.31NCBI
HuRef634,482,565 - 34,568,027 (+)NCBIHuRef
CHM1_1634,761,891 - 34,847,345 (+)NCBICHM1_1
T2T-CHM13v2.0634,614,874 - 34,700,320 (+)NCBIT2T-CHM13v2.0
Bltp3a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391728,075,481 - 28,119,014 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1728,075,415 - 28,119,015 (+)EnsemblGRCm39 Ensembl
GRCm381727,856,507 - 27,900,040 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1727,856,441 - 27,900,041 (+)EnsemblGRCm38mm10GRCm38
MGSCv371727,993,452 - 28,036,985 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361727,583,387 - 27,627,630 (+)NCBIMGSCv36mm8
Celera1728,409,281 - 28,453,282 (+)NCBICelera
Cytogenetic Map17A3.3NCBI
cM Map1714.59NCBI
Bltp3a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554372,875,835 - 2,904,114 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554372,844,544 - 2,905,073 (+)NCBIChiLan1.0ChiLan1.0
BLTP3A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2549,261,172 - 49,344,867 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1645,129,903 - 45,212,251 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0634,356,919 - 34,439,105 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1635,453,735 - 35,536,405 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl635,453,735 - 35,538,846 (+)Ensemblpanpan1.1panPan2
BLTP3A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1124,027,333 - 4,087,988 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl124,027,455 - 4,089,578 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha124,039,412 - 4,103,264 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0124,360,073 - 4,423,970 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl124,359,752 - 4,425,564 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1124,020,178 - 4,084,147 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0124,101,125 - 4,165,202 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0124,201,231 - 4,265,219 (+)NCBIUU_Cfam_GSD_1.0
Bltp3a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494639,601,705 - 39,674,406 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647624,290,182 - 24,358,337 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647624,273,233 - 24,358,518 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
BLTP3A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl730,731,461 - 30,802,735 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1730,731,466 - 30,799,958 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2735,474,824 - 35,540,338 (+)NCBISscrofa10.2Sscrofa10.2susScr3
BLTP3A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11737,241,841 - 37,322,220 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1737,246,908 - 37,321,337 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604434,710,150 - 34,792,452 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Bltp3a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475422,476,430 - 22,536,630 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475422,474,951 - 22,536,828 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Bltp3a
344 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:74
Count of miRNA genes:72
Interacting mature miRNAs:74
Transcripts:ENSRNOT00000049592
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1641915Colcr9Colorectal carcinoma resistance QTL 92.970.0024intestine integrity trait (VT:0010554)benign colorectal tumor number (CMO:0001795)20153065546530655Rat
2317057Aia27Adjuvant induced arthritis QTL 272.83joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)20289259726381954Rat
61474Eae1Experimental allergic encephalomyelitis QTL 13nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)2046066076691706Rat
7411668Foco32Food consumption QTL 3280.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20136600972Rat
2305926Iddm37Insulin dependent diabetes mellitus QTL 376blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)20152784246527842Rat
1354642Despr15Despair related QTL 150.0027locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)20124159021Rat
1600382Edcs3Endometrial carcinoma susceptibility QTL33.50.003uterus morphology trait (VT:0001120)percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)20125159026Rat
1558640Prcs2Prostate cancer susceptibility QTL 23.3prostate integrity trait (VT:0010571)percentage of study population developing ventral prostate tumorous lesions during a period of time (CMO:0000943)20460660717617956Rat
1331772Cdexp2CD45RC expression in CD8 T cells QTL 25.7CD8-positive T cell quantity (VT:0008077)blood CD45RC(high) CD8 T cell count to CD45RC(low) CD8 T cell count ratio (CMO:0001990)20362164910078919Rat
8694189Bw153Body weight QTL 1533.130.001body mass (VT:0001259)body weight gain (CMO:0000420)20129191651Rat
1300152Bp195Blood pressure QTL 1953.46arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2036216499243559Rat
4889857Pur27Proteinuria QTL 2712.20.001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)20460660717617956Rat
9590109Sffal8Serum free fatty acids level QTL 85.320.01blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)20129191651Rat
9590275Scort15Serum corticosterone level QTL 153.480.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20129191651Rat
9589155Insul32Insulin level QTL 326.380.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)20129191651Rat
7411650Foco23Food consumption QTL 2320.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20129191651Rat
2317851Alcrsp22Alcohol response QTL 223.20.05response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)20127339237Rat
1598816Memor12Memory QTL 122.4exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)20260683647606836Rat
61432Cia1Collagen induced arthritis QTL 1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)20362165614101050Rat
1641893Alcrsp7Alcohol response QTL 7response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)20127339237Rat
6893685Bw111Body weight QTL 1112.70.004body mass (VT:0001259)body weight (CMO:0000012)20132578807Rat
9590252Scort12Serum corticosterone level QTL 1220.460.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20136600972Rat

Markers in Region
BE108400  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2205,905,452 - 5,905,628 (+)MAPPERmRatBN7.2
Rnor_6.0207,426,396 - 7,426,571NCBIRnor6.0
Rnor_5.0209,628,421 - 9,628,596UniSTSRnor5.0
RGSC_v3.4206,062,657 - 6,062,832UniSTSRGSC3.4
Celera207,466,308 - 7,466,483UniSTS
RH 3.4 Map2058.9UniSTS
Cytogenetic Map20p12UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000049592   ⟹   ENSRNOP00000046054
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl205,910,260 - 5,949,472 (+)Ensembl
Rnor_6.0 Ensembl207,431,355 - 7,471,900 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000102198   ⟹   ENSRNOP00000081841
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl205,910,329 - 5,952,404 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000103992   ⟹   ENSRNOP00000076558
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl205,910,260 - 5,952,404 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000104971   ⟹   ENSRNOP00000087799
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl205,929,917 - 5,952,404 (+)Ensembl
RefSeq Acc Id: XM_002728921   ⟹   XP_002728967
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8205,912,033 - 5,956,404 (+)NCBI
mRatBN7.2205,910,261 - 5,954,641 (+)NCBI
Rnor_6.0207,431,235 - 7,475,515 (+)NCBI
Rnor_5.0209,633,259 - 9,677,553 (+)NCBI
RGSC_v3.4206,067,567 - 6,108,468 (+)RGD
Sequence:
RefSeq Acc Id: XM_039099274   ⟹   XP_038955202
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8205,926,746 - 5,956,404 (+)NCBI
mRatBN7.2205,925,365 - 5,954,641 (+)NCBI
RefSeq Acc Id: XM_039099275   ⟹   XP_038955203
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8205,912,396 - 5,956,404 (+)NCBI
mRatBN7.2205,910,624 - 5,954,641 (+)NCBI
RefSeq Acc Id: XM_039099276   ⟹   XP_038955204
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8205,938,411 - 5,956,404 (+)NCBI
mRatBN7.2205,936,635 - 5,954,641 (+)NCBI
RefSeq Acc Id: XR_005497711
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8205,912,070 - 5,951,934 (+)NCBI
mRatBN7.2205,910,299 - 5,950,171 (+)NCBI
RefSeq Acc Id: XP_002728967   ⟸   XM_002728921
- Peptide Label: isoform X2
- UniProtKB: A0A8I6A3T8 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000046054   ⟸   ENSRNOT00000049592
RefSeq Acc Id: XP_038955203   ⟸   XM_039099275
- Peptide Label: isoform X1
- UniProtKB: A6JJN8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038955202   ⟸   XM_039099274
- Peptide Label: isoform X1
- UniProtKB: A6JJN8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038955204   ⟸   XM_039099276
- Peptide Label: isoform X3
- UniProtKB: A6JJN8 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000076558   ⟸   ENSRNOT00000103992
Ensembl Acc Id: ENSRNOP00000087799   ⟸   ENSRNOT00000104971
Ensembl Acc Id: ENSRNOP00000081841   ⟸   ENSRNOT00000102198
Protein Domains
Chorein N-terminal

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZMR2-F1-model_v2 AlphaFold D3ZMR2 1-1448 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13701456
Promoter ID:EPDNEW_R11977
Type:initiation region
Name:Uhrf1bp1_1
Description:UHRF1 binding protein 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0207,431,261 - 7,431,321EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1307264 AgrOrtholog
BioCyc Gene G2FUF-4455 BioCyc
Ensembl Genes ENSRNOG00000000495 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000049592.6 UniProtKB/TrEMBL
  ENSRNOT00000102198.1 UniProtKB/TrEMBL
  ENSRNOT00000103992.1 UniProtKB/TrEMBL
  ENSRNOT00000104971.1 UniProtKB/TrEMBL
InterPro UHRF1BP1_like UniProtKB/TrEMBL
  VPS13A_N UniProtKB/TrEMBL
NCBI Gene 309637 ENTREZGENE
PANTHER PTHR22774 UniProtKB/TrEMBL
  UHRF1-BINDING PROTEIN 1 UniProtKB/TrEMBL
Pfam Chorein_N UniProtKB/TrEMBL
PhenoGen Bltp3a PhenoGen
RatGTEx ENSRNOG00000000495 RatGTEx
UniProt A0A8I5Y6T9_RAT UniProtKB/TrEMBL
  A0A8I5ZTR4_RAT UniProtKB/TrEMBL
  A0A8I6A3T8 ENTREZGENE, UniProtKB/TrEMBL
  A6JJN8 ENTREZGENE, UniProtKB/TrEMBL
  D3ZMR2_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-06-17 Bltp3a  bridge-like lipid transfer protein family member 3A  Uhrf1bp1  UHRF1 binding protein 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2012-10-10 Uhrf1bp1  UHRF1 binding protein 1  RGD1307264  similar to hypothetical protein FLJ20302; similar to CG31653-PA  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 RGD1307264  similar to hypothetical protein FLJ20302; similar to CG31653-PA   RGD1307264_predicted  similar to hypothetical protein FLJ20302; similar to CG31653-PA (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-20 RGD1307264_predicted  similar to hypothetical protein FLJ20302; similar to CG31653-PA (predicted)  LOC309637_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC309637_predicted  similar to hypothetical protein FLJ20302; similar to CG31653-PA (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL