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Gene: Olr1 (oxidized low density lipoprotein receptor 1) Rattus norvegicus
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Symbol: Olr1
Name: oxidized low density lipoprotein receptor 1
Description: Predicted to have identical protein binding activity and low-density lipoprotein particle receptor activity. Involved in several processes, including leukocyte cell-cell adhesion; lipoprotein metabolic process; and response to hydrogen peroxide. Predicted to localize to nucleoplasm; plasma membrane; and receptor complex. Biomarker of end stage renal failure and hypertension. Human ortholog(s) of this gene implicated in cerebral amyloid angiopathy; coronary artery disease; and myocardial infarction. Orthologous to human OLR1 (oxidized low density lipoprotein receptor 1); PARTICIPATES IN angiotensin II signaling pathway; eicosanoid signaling pathway via peroxisome proliferator-activated receptor gamma; phagocytosis pathway; INTERACTS WITH (+)-schisandrin B; 1-naphthyl isothiocyanate; acetamide.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: lectin-like oxidized LDL receptor 1; lectin-like oxidized low-density lipoprotein receptor; Lectin-like oxidized low-density lipoprotein receptor-1; lectin-like oxLDL receptor 1; lectin-type oxidized LDL receptor 1; LOX-1; Oldlr1; Oldr1; ox-LDL receptor 1; oxidised low density lipoprotein (lectin-like) receptor 1; oxidized low density lipoprotein (lectin-like) receptor 1; oxidized low-density lipoprotein receptor 1
Orthologs:
Homo sapiens (human) : OLR1 (oxidized low density lipoprotein receptor 1)  HGNC  Alliance
Mus musculus (house mouse) : Olr1 (oxidized low density lipoprotein (lectin-like) receptor 1)  MGI  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : OLR1 (oxidized low density lipoprotein receptor 1)
Canis lupus familiaris (dog) : OLR1 (oxidized low density lipoprotein receptor 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Olr1 (oxidized low density lipoprotein receptor 1)
Sus scrofa (pig) : OLR1 (oxidized low density lipoprotein receptor 1)
Chlorocebus sabaeus (African green monkey) : OLR1 (oxidized low density lipoprotein receptor 1)
Heterocephalus glaber (naked mole-rat) : Olr1 (oxidized low density lipoprotein receptor 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.04163,239,853 - 163,261,937 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4163,239,849 - 163,261,958 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04211,883,405 - 211,905,489 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44166,747,228 - 166,769,340 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.14166,992,163 - 167,014,276 (-)NCBI
Celera4151,610,779 - 151,632,854 (-)NCBICelera
Cytogenetic Map4q42NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Olr1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 620515
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.