Predicted to have identical protein binding activity and low-density lipoprotein particle receptor activity. Involved in several processes, including leukocyte cell-cell adhesion; lipoprotein metabolic process; and response to hydrogen peroxide. Predicted to localize to nucleoplasm; plasma membrane; and receptor complex. Biomarker of end stage renal failure and hypertension. Human ortholog(s) of this gene implicated in cerebral amyloid angiopathy; coronary artery disease; and myocardial infarction. Orthologous to human OLR1 (oxidized low density lipoprotein receptor 1); PARTICIPATES IN angiotensin II signaling pathway; eicosanoid signaling pathway via peroxisome proliferator-activated receptor gamma; phagocytosis pathway; INTERACTS WITH (+)-schisandrin B; 1-naphthyl isothiocyanate; acetamide.
Spironolactone inhibits the reaction [Aldosterone results in increased expression of OLR1 mRNA], Spironolactone inhibits the reaction [Aldosterone results in increased expression of OLR1 protein]
Amlodipine inhibits the reaction [AGT results in increased expression of OLR1 mRNA], Amlodipine inhibits the reaction [AGT results in increased expression of OLR1 protein]
[Niacin co-treated with Chromium] inhibits the reaction [Dietary Fats results in increased expression of OLR1 mRNA], [Niacin co-treated with Chromium] inhibits the reaction [Dietary Fats results in increased expression of OLR1 protein]
[Clofibrate co-treated with Acetaminophen] affects the expression of OLR1 mRNA, PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of OLR1 mRNA]
[1-methylanthracene co-treated with fluoranthene] results in increased expression of OLR1 mRNA, SB 203580 inhibits the reaction [[1-methylanthracene co-treated with fluoranthene] results in increased expression of OLR1 mRNA]
telmisartan inhibits the reaction [Lipopolysaccharides results in increased expression of OLR1 mRNA], telmisartan inhibits the reaction [Lipopolysaccharides results in increased expression of OLR1 protein]
Metformin affects the reaction [Dehydroepiandrosterone results in increased expression of OLR1 protein], Metformin inhibits the reaction [Dehydroepiandrosterone results in increased expression of OLR1 mRNA]
methyllycaconitine inhibits the reaction [Varenicline results in increased expression of OLR1 mRNA], methyllycaconitine inhibits the reaction [Varenicline results in increased expression of OLR1 protein]
[Niacin co-treated with Chromium] inhibits the reaction [Dietary Fats results in increased expression of OLR1 mRNA], [Niacin co-treated with Chromium] inhibits the reaction [Dietary Fats results in increased expression of OLR1 protein]
[Clofibrate co-treated with Acetaminophen] affects the expression of OLR1 mRNA, PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of OLR1 mRNA]
Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of OLR1 mRNA], demethoxycurcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of OLR1 mRNA]
[Quercetin co-treated with Ascorbic Acid] results in increased expression of OLR1 mRNA, Quercetin inhibits the reaction [Lipids results in increased expression of OLR1]
Quercetin affects the reaction [Dehydroepiandrosterone results in increased expression of OLR1 protein], Quercetin inhibits the reaction [Dehydroepiandrosterone results in increased expression of OLR1 mRNA]
resveratrol inhibits the reaction [[Cholesterol co-treated with Ergosterol] results in increased expression of OLR1 mRNA], resveratrol inhibits the reaction [[Cholesterol co-treated with Ergosterol] results in increased expression of OLR1 protein]
Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of OLR1 protein], caffeic acid phenethyl ester inhibits the reaction [sodium arsenite results in increased expression of OLR1 protein]
Spironolactone inhibits the reaction [Aldosterone results in increased expression of OLR1 mRNA], Spironolactone inhibits the reaction [Aldosterone results in increased expression of OLR1 protein]
Telmisartan inhibits the reaction [Lipopolysaccharides results in increased expression of OLR1 mRNA], Telmisartan inhibits the reaction [Lipopolysaccharides results in increased expression of OLR1 protein]
methyllycaconitine inhibits the reaction [Varenicline results in increased expression of OLR1 mRNA], methyllycaconitine inhibits the reaction [Varenicline results in increased expression of OLR1 protein]
Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Gene-Chemical Interaction Annotations
