Eif4e2 (eukaryotic translation initiation factor 4E family member 2) - Rat Genome Database

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Gene: Eif4e2 (eukaryotic translation initiation factor 4E family member 2) Rattus norvegicus
Analyze
Symbol: Eif4e2 (Ensembl: Chrng)
Name: eukaryotic translation initiation factor 4E family member 2 (Ensembl:cholinergic receptor nicotinic gamma subunit)
RGD ID: 1307790
Description: Predicted to enable RNA cap binding activity; translation initiation factor activity; and ubiquitin protein ligase binding activity. Predicted to be involved in negative regulation of translational initiation; negative regulation of type I interferon-mediated signaling pathway; and translation. Predicted to act upstream of with a positive effect on miRNA-mediated gene silencing by inhibition of translation. Predicted to act upstream of or within in utero embryonic development and negative regulation of translation. Predicted to be located in P-body. Predicted to be part of eukaryotic translation initiation factor 4F complex. Orthologous to human EIF4E2 (eukaryotic translation initiation factor 4E family member 2); PARTICIPATES IN insulin signaling pathway; mTOR signaling pathway; RNA transport pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Eif4el3; eukaryotic translation initiation factor 4E like 3; eukaryotic translation initiation factor 4E member 2; eukaryotic translation initiation factor 4E type 2; LOC363275
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8995,333,439 - 95,362,366 (+)NCBIGRCr8
mRatBN7.2987,886,126 - 87,914,470 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl987,878,085 - 87,914,482 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx996,310,117 - 96,338,457 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.09101,446,376 - 101,474,717 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0999,814,382 - 99,842,727 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0994,310,476 - 94,325,445 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl994,307,852 - 94,336,831 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0994,034,066 - 94,048,590 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4986,020,090 - 86,034,739 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1986,209,427 - 86,223,947 (+)NCBI
Celera985,299,345 - 85,313,492 (+)NCBICelera
Cytogenetic Map9q35NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
4. GOA pipeline RGD automated data pipeline
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:14623119   PMID:17368478   PMID:22681889   PMID:22751931   PMID:25931508  


Genomics

Comparative Map Data
Eif4e2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8995,333,439 - 95,362,366 (+)NCBIGRCr8
mRatBN7.2987,886,126 - 87,914,470 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl987,878,085 - 87,914,482 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx996,310,117 - 96,338,457 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.09101,446,376 - 101,474,717 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0999,814,382 - 99,842,727 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0994,310,476 - 94,325,445 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl994,307,852 - 94,336,831 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0994,034,066 - 94,048,590 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4986,020,090 - 86,034,739 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1986,209,427 - 86,223,947 (+)NCBI
Celera985,299,345 - 85,313,492 (+)NCBICelera
Cytogenetic Map9q35NCBI
EIF4E2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382232,550,689 - 232,583,644 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2232,550,659 - 232,583,644 (+)EnsemblGRCh38hg38GRCh38
GRCh372233,415,399 - 233,448,354 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362233,123,601 - 233,142,164 (+)NCBINCBI36Build 36hg18NCBI36
Build 342233,240,861 - 233,259,424NCBI
Celera2227,179,671 - 227,198,211 (+)NCBICelera
Cytogenetic Map2q37.1NCBI
HuRef2225,266,265 - 225,284,791 (+)NCBIHuRef
CHM1_12233,421,455 - 233,440,003 (+)NCBICHM1_1
T2T-CHM13v2.02233,037,473 - 233,070,437 (+)NCBIT2T-CHM13v2.0
Eif4e2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39187,141,633 - 87,168,210 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl187,141,636 - 87,168,210 (+)EnsemblGRCm39 Ensembl
GRCm38187,213,911 - 87,240,488 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl187,213,914 - 87,240,488 (+)EnsemblGRCm38mm10GRCm38
MGSCv37189,110,489 - 89,137,063 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36189,045,085 - 89,071,659 (+)NCBIMGSCv36mm8
Celera190,187,044 - 90,213,677 (+)NCBICelera
Cytogenetic Map1C5NCBI
cM Map144.08NCBI
Eif4e2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554533,395,483 - 3,424,649 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554533,395,483 - 3,424,649 (-)NCBIChiLan1.0ChiLan1.0
EIF4E2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v213135,155,930 - 135,188,847 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B135,170,916 - 135,206,124 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B119,782,057 - 119,814,992 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B238,700,790 - 238,733,654 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B238,700,790 - 238,733,654 (+)Ensemblpanpan1.1panPan2
EIF4E2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12544,192,037 - 44,203,401 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2544,192,038 - 44,214,631 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2544,680,329 - 44,697,768 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02544,443,041 - 44,474,295 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2544,443,122 - 44,474,293 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12544,368,971 - 44,386,399 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02544,214,278 - 44,231,925 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02544,369,621 - 44,387,066 (+)NCBIUU_Cfam_GSD_1.0
Eif4e2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303186,390,370 - 186,420,009 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365254,519,724 - 4,549,364 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365254,519,709 - 4,549,364 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
EIF4E2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl15133,060,247 - 133,103,719 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.115133,060,054 - 133,092,624 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215146,959,731 - 147,047,863 (+)NCBISscrofa10.2Sscrofa10.2susScr3
EIF4E2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.110118,571,490 - 118,605,084 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl10118,571,533 - 118,607,336 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604080,898,060 - 80,930,759 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Eif4e2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248435,303,172 - 5,332,228 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248435,303,157 - 5,332,228 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Eif4e2
94 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:124
Count of miRNA genes:96
Interacting mature miRNAs:117
Transcripts:ENSRNOT00000026646, ENSRNOT00000065743
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
724544Uae9Urinary albumin excretion QTL 94.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)925268044114175309Rat
731164Uae25Urinary albumin excretion QTL 253.50.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)925661188100929786Rat
8662828Vetf6Vascular elastic tissue fragility QTL 63.9artery integrity trait (VT:0010639)patent ductus arteriosus score (CMO:0002566)93696235992058970Rat
2290450Scl57Serum cholesterol level QTL 574.15blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)93696235995410867Rat
10058949Gmadr5Adrenal mass QTL 520.014adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)94279151387976209Rat
11353951Bp394Blood pressure QTL 394arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)94464992189649921Rat
12879506Pur33Proteinuria QTL 33urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)94464992189649921Rat
11353957Bmd92Bone mineral density QTL 920.01tibia mineral mass (VT:1000283)volumetric bone mineral density (CMO:0001553)94611419991114199Rat
631656Bp108Blood pressure QTL 1085.970.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)94859825193598251Rat
1578760Cm53Cardiac mass QTL 533.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)956771635101771635Rat
724515Uae16Urinary albumin excretion QTL 168urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)958163035100929646Rat
1300134Bp185Blood pressure QTL 1853.73arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)961381434104821652Rat
1581580Uae34Urinary albumin excretion QTL 34urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)96207227596470995Rat
1578757Pur6Proteinuria QTL 63.30.005urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)96207227596470995Rat
61385Edpm9Estrogen-dependent pituitary mass QTL 93.430.05pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)963869687108869687Rat
731171Glom6Glomerulus QTL 62.80.0003kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)964573531109573531Rat
1354626Bvd1Brain ventricular dilatation QTL 13.730.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)975712843111552878Rat
4889852Pur26Proteinuria QTL 26150.001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)977813894101597663Rat
7794784Mcs31Mammary carcinoma susceptibility QTL 312.98mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)977813894111552878Rat
2303178Bp334Blood pressure QTL 3343.70.01arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)97927151191616855Rat
2303178Bp334Blood pressure QTL 3343.70.01arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)97927151191616855Rat
2303178Bp334Blood pressure QTL 3343.70.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)97927151191616855Rat
724547Cm21Cardiac mass QTL 212.7heart mass (VT:0007028)calculated heart weight (CMO:0000073)979271511102910209Rat
4889943Bss90Bone structure and strength QTL 904.1tibia area (VT:1000281)tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)98636963192058970Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 57 41 19 41 8 11 74 35 41 11 8
Low
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001402203 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001402204 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001402205 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001402206 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001402208 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063267448 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063267449 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide BC158817 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH474004 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219916 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ220431 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ226325 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ230152 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ231706 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ232529 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ233059 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ233479 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000009 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSRNOT00000026646   ⟹   ENSRNOP00000026646
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl987,886,111 - 87,902,501 (+)Ensembl
Rnor_6.0 Ensembl994,310,921 - 94,326,889 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000065743   ⟹   ENSRNOP00000061077
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl994,310,469 - 94,325,445 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000077005   ⟹   ENSRNOP00000068342
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl987,886,078 - 87,901,058 (+)Ensembl
Rnor_6.0 Ensembl994,316,717 - 94,325,452 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000085476   ⟹   ENSRNOP00000074842
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl987,886,469 - 87,902,502 (+)Ensembl
Rnor_6.0 Ensembl994,307,852 - 94,326,898 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000092493   ⟹   ENSRNOP00000075858
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl987,886,111 - 87,909,300 (+)Ensembl
Rnor_6.0 Ensembl994,324,793 - 94,336,497 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000092534   ⟹   ENSRNOP00000075812
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl987,886,061 - 87,907,117 (+)Ensembl
Rnor_6.0 Ensembl994,316,717 - 94,336,831 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000094157   ⟹   ENSRNOP00000085673
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl987,886,469 - 87,914,464 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000106438   ⟹   ENSRNOP00000085634
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl987,878,085 - 87,884,193 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000108778   ⟹   ENSRNOP00000097951
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl987,886,078 - 87,914,482 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000114104   ⟹   ENSRNOP00000077974
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl987,883,529 - 87,903,286 (+)Ensembl
RefSeq Acc Id: NM_001402203   ⟹   NP_001389132
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8995,334,025 - 95,350,398 (+)NCBI
mRatBN7.2987,886,126 - 87,902,502 (+)NCBI
RefSeq Acc Id: NM_001402204   ⟹   NP_001389133
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8995,334,386 - 95,350,398 (+)NCBI
mRatBN7.2987,886,487 - 87,902,502 (+)NCBI
RefSeq Acc Id: NM_001402205   ⟹   NP_001389134
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8995,334,025 - 95,362,366 (+)NCBI
mRatBN7.2987,886,126 - 87,914,470 (+)NCBI
RefSeq Acc Id: NM_001402206   ⟹   NP_001389135
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8995,334,386 - 95,362,366 (+)NCBI
mRatBN7.2987,886,487 - 87,914,470 (+)NCBI
RefSeq Acc Id: NM_001402208   ⟹   NP_001389137
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8995,334,386 - 95,362,366 (+)NCBI
mRatBN7.2987,886,487 - 87,914,470 (+)NCBI
RefSeq Acc Id: XM_063267448   ⟹   XP_063123518
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8995,333,439 - 95,362,366 (+)NCBI
RefSeq Acc Id: XM_063267449   ⟹   XP_063123519
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8995,333,439 - 95,362,366 (+)NCBI
RefSeq Acc Id: ENSRNOP00000075812   ⟸   ENSRNOT00000092534
RefSeq Acc Id: ENSRNOP00000075858   ⟸   ENSRNOT00000092493
RefSeq Acc Id: ENSRNOP00000068342   ⟸   ENSRNOT00000077005
RefSeq Acc Id: ENSRNOP00000026646   ⟸   ENSRNOT00000026646
RefSeq Acc Id: ENSRNOP00000074842   ⟸   ENSRNOT00000085476
RefSeq Acc Id: ENSRNOP00000061077   ⟸   ENSRNOT00000065743
RefSeq Acc Id: ENSRNOP00000097951   ⟸   ENSRNOT00000108778
RefSeq Acc Id: ENSRNOP00000085634   ⟸   ENSRNOT00000106438
RefSeq Acc Id: ENSRNOP00000077974   ⟸   ENSRNOT00000114104
RefSeq Acc Id: ENSRNOP00000085673   ⟸   ENSRNOT00000094157
RefSeq Acc Id: NP_001389134   ⟸   NM_001402205
- Peptide Label: isoform 3
- UniProtKB: A0A0U1RRU1 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001389132   ⟸   NM_001402203
- Peptide Label: isoform 1
- UniProtKB: B0BNH0 (UniProtKB/TrEMBL),   A0A8I5YC42 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001389135   ⟸   NM_001402206
- Peptide Label: isoform 4
- UniProtKB: A0A8I6AX14 (UniProtKB/TrEMBL),   A0A8I5YC42 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001389137   ⟸   NM_001402208
- Peptide Label: isoform 5
- UniProtKB: A0A8I6A0N7 (UniProtKB/TrEMBL),   A0A8I5YC42 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001389133   ⟸   NM_001402204
- Peptide Label: isoform 2
- UniProtKB: F1M470 (UniProtKB/TrEMBL),   A0A8I5YC42 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063123518   ⟸   XM_063267448
- Peptide Label: isoform X1
- UniProtKB: A0A0U1RRU1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063123519   ⟸   XM_063267449
- Peptide Label: isoform X2
- UniProtKB: A0A0U1RRU1 (UniProtKB/TrEMBL)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2K933-F1-model_v2 AlphaFold A0A0G2K933 1-256 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13696831
Promoter ID:EPDNEW_R7356
Type:initiation region
Name:Eif4e2_2
Description:eukaryotic translation initiation factor 4E family member 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R7357  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0994,310,533 - 94,310,593EPDNEW
RGD ID:13696835
Promoter ID:EPDNEW_R7357
Type:initiation region
Name:Eif4e2_1
Description:eukaryotic translation initiation factor 4E family member 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R7356  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0994,310,912 - 94,310,972EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1307790 AgrOrtholog
BioCyc Gene G2FUF-26848 BioCyc
Ensembl Genes ENSRNOG00000019634 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000026646 ENTREZGENE
  ENSRNOT00000026646.6 UniProtKB/TrEMBL
  ENSRNOT00000077005.2 UniProtKB/TrEMBL
  ENSRNOT00000085476.2 UniProtKB/TrEMBL
  ENSRNOT00000092493.2 UniProtKB/TrEMBL
  ENSRNOT00000092534 ENTREZGENE
  ENSRNOT00000092534.2 UniProtKB/TrEMBL
  ENSRNOT00000094157 ENTREZGENE
  ENSRNOT00000094157.1 UniProtKB/TrEMBL
  ENSRNOT00000108778 ENTREZGENE
  ENSRNOT00000108778.1 UniProtKB/TrEMBL
  ENSRNOT00000114104 ENTREZGENE
  ENSRNOT00000114104.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.760.10 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7374173 IMAGE-MGC_LOAD
InterPro TIF_eIF4e-like_dom UniProtKB/TrEMBL
  TIF_eIF_4E UniProtKB/TrEMBL
  TIF_eIF_4E_CS UniProtKB/TrEMBL
KEGG Report rno:363275 UniProtKB/TrEMBL
MGC_CLONE MGC:188257 IMAGE-MGC_LOAD
NCBI Gene 363275 ENTREZGENE
PANTHER EUKARYOTIC TRANSLATION INITIATION FACTOR 4E TYPE 2 UniProtKB/TrEMBL
  TIF_eIF_4E UniProtKB/TrEMBL
Pfam IF4E UniProtKB/TrEMBL
PhenoGen Eif4e2 PhenoGen
PROSITE IF4E UniProtKB/TrEMBL
RatGTEx ENSRNOG00000019634 RatGTEx
Superfamily-SCOP TIF_eIF_4E UniProtKB/TrEMBL
UniProt A0A096MK14_RAT UniProtKB/TrEMBL
  A0A0G2K933_RAT UniProtKB/TrEMBL
  A0A0U1RRU1 ENTREZGENE, UniProtKB/TrEMBL
  A0A0U1RRY1_RAT UniProtKB/TrEMBL
  A0A8I5YC42 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A0N7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AX14 ENTREZGENE, UniProtKB/TrEMBL
  B0BNH0 ENTREZGENE, UniProtKB/TrEMBL
  F1M470 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary D4A174 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2010-04-20 Eif4e2  eukaryotic translation initiation factor 4E family member 2  Eif4e2  eukaryotic translation initiation factor 4E member 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Eif4e2  eukaryotic translation initiation factor 4E member 2   Eif4e2_predicted  eukaryotic translation initiation factor 4E member 2 (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-30 Eif4e2_predicted  eukaryotic translation initiation factor 4E member 2 (predicted)  Eif4el3_predicted  eukaryotic translation initiation factor 4E like 3 (predicted)  Symbol and Name updated 1299863 APPROVED
2005-01-12 Eif4el3_predicted  eukaryotic translation initiation factor 4E like 3 (predicted)      Symbol and Name status set to approved 70820 APPROVED