Bag6 (BAG cochaperone 6) - Rat Genome Database

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Gene: Bag6 (BAG cochaperone 6) Rattus norvegicus
Analyze
Symbol: Bag6
Name: BAG cochaperone 6
RGD ID: 71064
Description: Predicted to enable several functions, including Hsp70 protein binding activity; enzyme binding activity; and misfolded protein binding activity. Involved in regulation of cell population proliferation. Located in cytoplasm. Human ortholog(s) of this gene implicated in lung non-small cell carcinoma and osteoarthritis. Orthologous to human BAG6 (BAG cochaperone 6); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,4-dinitrotoluene; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Bat3; BCL2-associated athanogene 6; HLA-B associated transcript 3; HLA-B-associated transcript 3; large proline-rich protein BAG6; large proline-rich protein BAT3
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2203,675,938 - 3,690,414 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl203,675,938 - 3,688,657 (-)Ensembl
Rnor_6.0205,124,512 - 5,138,084 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl205,125,349 - 5,138,084 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0207,198,613 - 7,211,343 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4203,739,593 - 3,752,311 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1203,739,819 - 3,752,493 (-)NCBI
Celera204,336,986 - 4,349,704 (+)NCBICelera
Cytogenetic Map20p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
apoptotic process  (IEA,ISO,ISS)
brain development  (ISO,ISS)
cell differentiation  (IEA)
chromatin organization  (IEA)
endoplasmic reticulum stress-induced pre-emptive quality control  (ISO,ISS)
ER-associated misfolded protein catabolic process  (IEA,ISO,ISS)
immune response-activating cell surface receptor signaling pathway  (IEA,ISO)
immune system process  (IEA)
internal peptidyl-lysine acetylation  (ISO,ISS)
intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator  (IEA,ISO,ISS)
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress  (ISO,ISS)
kidney development  (IEA,ISO,ISS)
lung development  (IEA,ISO,ISS)
maintenance of unfolded protein involved in ERAD pathway  (ISO)
natural killer cell activation  (IEA,ISO)
negative regulation of apoptotic process  (ISO)
negative regulation of proteasomal ubiquitin-dependent protein catabolic process  (IEA,ISO,ISS)
negative regulation of proteolysis  (ISO,ISS)
positive regulation of ERAD pathway  (ISO)
posttranslational protein targeting to endoplasmic reticulum membrane  (IEA,ISO)
proteasomal protein catabolic process  (ISO,ISS)
proteasome-mediated ubiquitin-dependent protein catabolic process  (ISO)
protein stabilization  (ISO,ISS)
regulation of apoptotic process  (ISO)
regulation of cell population proliferation  (IEP)
regulation of embryonic development  (ISO,ISS)
regulation of protein stability  (ISO)
spermatogenesis  (IEA,ISO,ISS)
synaptonemal complex assembly  (IEA,ISO,ISS)
tail-anchored membrane protein insertion into ER membrane  (ISO,ISS)
ubiquitin-dependent ERAD pathway  (IBA,ISO,ISS)
ubiquitin-dependent protein catabolic process  (ISO,ISS)

Cellular Component
BAT3 complex  (IBA,ISO,ISS)
cytoplasm  (IDA,ISO)
cytosol  (IEA,ISO,ISS)
extracellular exosome  (IEA,ISO)
extracellular region  (IEA)
intracellular membrane-bounded organelle  (ISO)
membrane  (ISO)
nucleoplasm  (IEA,ISO)
nucleus  (IEA,ISO,ISS)

References

Additional References at PubMed
PMID:10777571   PMID:12477932   PMID:14960581   PMID:15060004   PMID:16287848   PMID:17403783   PMID:18056262   PMID:18487607   PMID:18678708   PMID:18852879   PMID:19946888   PMID:20676083  
PMID:20713601   PMID:21460186   PMID:21636303   PMID:22871113   PMID:23129660   PMID:23246001   PMID:24133212   PMID:24424410   PMID:24981174   PMID:25535373   PMID:26565908   PMID:26692333  
PMID:27501752   PMID:29042515   PMID:30053369  


Genomics

Comparative Map Data
Bag6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2203,675,938 - 3,690,414 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl203,675,938 - 3,688,657 (-)Ensembl
Rnor_6.0205,124,512 - 5,138,084 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl205,125,349 - 5,138,084 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0207,198,613 - 7,211,343 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4203,739,593 - 3,752,311 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1203,739,819 - 3,752,493 (-)NCBI
Celera204,336,986 - 4,349,704 (+)NCBICelera
Cytogenetic Map20p12NCBI
BAG6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl631,639,028 - 31,652,705 (-)EnsemblGRCh38hg38GRCh38
GRCh38631,639,028 - 31,660,900 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37631,606,805 - 31,620,438 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36631,714,784 - 31,728,456 (-)NCBINCBI36hg18NCBI36
Build 34631,714,796 - 31,728,426NCBI
Celera633,205,026 - 33,218,698 (-)NCBI
Cytogenetic Map6p21.33NCBI
HuRef631,392,973 - 31,406,702 (-)NCBIHuRef
CHM1_1631,608,941 - 31,622,613 (-)NCBICHM1_1
Bag6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391735,354,132 - 35,366,297 (+)NCBIGRCm39mm39
GRCm39 Ensembl1735,354,154 - 35,366,298 (+)Ensembl
GRCm381735,135,156 - 35,147,321 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1735,135,178 - 35,147,322 (+)EnsemblGRCm38mm10GRCm38
MGSCv371735,272,187 - 35,284,181 (+)NCBIGRCm37mm9NCBIm37
MGSCv361734,743,298 - 34,755,292 (+)NCBImm8
Celera1738,232,179 - 38,244,173 (+)NCBICelera
Cytogenetic Map17B1NCBI
cM Map1718.59NCBI
Bag6
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955437176,797 - 188,003 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955437176,848 - 188,243 (-)NCBIChiLan1.0ChiLan1.0
BAG6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1632,190,037 - 32,204,321 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl632,190,037 - 32,204,321 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0631,300,126 - 31,313,829 (-)NCBIMhudiblu_PPA_v0panPan3
BAG6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1121,126,730 - 1,141,978 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl121,126,732 - 1,137,896 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha121,263,174 - 1,278,145 (-)NCBI
ROS_Cfam_1.0121,271,966 - 1,286,938 (-)NCBI
UMICH_Zoey_3.1121,131,332 - 1,146,287 (-)NCBI
UNSW_CanFamBas_1.0121,198,583 - 1,213,550 (-)NCBI
UU_Cfam_GSD_1.0121,265,643 - 1,280,617 (-)NCBI
Bag6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494635,676,078 - 35,695,078 (-)NCBI
SpeTri2.0NW_0049367271,866,235 - 1,885,266 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
BAG6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl723,756,897 - 23,775,893 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1723,756,897 - 23,768,659 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2727,483,304 - 27,495,077 (+)NCBISscrofa10.2Sscrofa10.2susScr3
BAG6
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Vero_WHO_p1.0NW_02366604431,548,910 - 31,563,916 (-)NCBIVero_WHO_p1.0
Bag6
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462475424,559,483 - 24,571,073 (+)NCBIHetGla_female_1.0hetGla2

Position Markers
AA900379  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2203,676,386 - 3,676,977 (-)MAPPERmRatBN7.2
Rnor_6.0205,137,045 - 5,137,635NCBIRnor6.0
Rnor_5.0207,210,304 - 7,210,894UniSTSRnor5.0
RGSC_v3.4203,740,042 - 3,740,632UniSTSRGSC3.4
Celera204,348,665 - 4,349,255UniSTS
RH 3.4 Map2053.1UniSTS
Cytogenetic Map20p12UniSTS
BE098892  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2203,688,930 - 3,689,103 (-)MAPPERmRatBN7.2
Rnor_6.0205,124,920 - 5,125,092NCBIRnor6.0
Rnor_5.0207,198,179 - 7,198,351UniSTSRnor5.0
RGSC_v3.4203,752,585 - 3,752,757UniSTSRGSC3.4
Celera204,336,540 - 4,336,712UniSTS
RH 3.4 Map2051.6UniSTS
Cytogenetic Map20p12UniSTS
RH126866  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2203,679,816 - 3,680,353 (-)MAPPERmRatBN7.2
Rnor_6.0205,133,669 - 5,134,205NCBIRnor6.0
Rnor_5.0207,206,928 - 7,207,464UniSTSRnor5.0
RGSC_v3.4203,743,472 - 3,744,008UniSTSRGSC3.4
Celera204,345,289 - 4,345,825UniSTS
Cytogenetic Map20p12UniSTS
RH35871  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2203,677,835 - 3,678,288 (-)MAPPERmRatBN7.2
Rnor_6.0205,135,734 - 5,136,186NCBIRnor6.0
Rnor_5.0207,208,993 - 7,209,445UniSTSRnor5.0
RGSC_v3.4203,741,491 - 3,741,943UniSTSRGSC3.4
Celera204,347,354 - 4,347,806UniSTS
Cytogenetic Map20p12UniSTS
MARC_5411-5412:996690356:1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2203,676,381 - 3,676,960 (-)MAPPERmRatBN7.2
Rnor_6.0205,137,062 - 5,137,640NCBIRnor6.0
Rnor_5.0207,210,321 - 7,210,899UniSTSRnor5.0
RGSC_v3.4203,740,037 - 3,740,615UniSTSRGSC3.4
Celera204,348,682 - 4,349,260UniSTS
Cytogenetic Map20p12UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354642Despr15Despair related QTL 150.0027locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)20124159021Rat
1600382Edcs3Endometrial carcinoma susceptibility QTL33.50.003uterus morphology trait (VT:0001120)percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)20125159026Rat
2317851Alcrsp22Alcohol response QTL 223.20.05response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)20127339237Rat
1641893Alcrsp7Alcohol response QTL 7response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)20127339237Rat
8694189Bw153Body weight QTL 1533.130.001body mass (VT:0001259)body weight gain (CMO:0000420)20129191651Rat
9590275Scort15Serum corticosterone level QTL 153.480.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20129191651Rat
7411650Foco23Food consumption QTL 2320.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20129191651Rat
9590109Sffal8Serum free fatty acids level QTL 85.320.01blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)20129191651Rat
9589155Insul32Insulin level QTL 326.380.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)20129191651Rat
6893685Bw111Body weight QTL 1112.70.004body mass (VT:0001259)body weight (CMO:0000012)20132578807Rat
7411668Foco32Food consumption QTL 3280.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20136600972Rat
9590252Scort12Serum corticosterone level QTL 1220.460.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20136600972Rat
2305926Iddm37Insulin dependent diabetes mellitus QTL 376blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)20152784246527842Rat
2306850Pia40Pristane induced arthritis QTL 400.0001joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)2015279595304575Rat
1641915Colcr9Colorectal carcinoma resistance QTL 92.970.0024intestine integrity trait (VT:0010554)benign colorectal tumor number (CMO:0001795)20153065546530655Rat
1598816Memor12Memory QTL 122.4exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)20260683647606836Rat
61448Ciaa1CIA Autoantibody QTL 1300.001blood autoantibody amount (VT:0003725)calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)2026463954597031Rat
61472Aia1Adjuvant induced arthritis QTL 1180.001joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)2026463954597031Rat
2317057Aia27Adjuvant induced arthritis QTL 272.83joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)20289259726381954Rat
1300152Bp195Blood pressure QTL 1953.46arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2036216499243559Rat
1331772Cdexp2CD45RC expression in CD8 T cells QTL 25.7CD8-positive T cell quantity (VT:0008077)blood CD45RC(high) CD8 T cell count to CD45RC(low) CD8 T cell count ratio (CMO:0001990)20362164910078919Rat
737973Pia21Pristane induced arthritis QTL 214.8joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)2036216564606812Rat
61432Cia1Collagen induced arthritis QTL 1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)20362165614101050Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:68
Count of miRNA genes:32
Interacting mature miRNAs:34
Transcripts:ENSRNOT00000001129, ENSRNOT00000060832
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 57 41 19 41 8 11 74 35 41 11 8
Low
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001033968 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_053609 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006256082 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006256083 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006256084 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006256085 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006256086 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006256087 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006256088 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006256089 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006256090 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006256091 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006256092 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006256093 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006256094 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039099133 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039099135 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039099136 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039099137 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039099138 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039099139 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039099140 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB018791 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC094348 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC100141 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BX883045 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH474121 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CK469699 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ223705 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000323 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000001129   ⟹   ENSRNOP00000001129
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl203,675,938 - 3,688,657 (-)Ensembl
Rnor_6.0 Ensembl205,125,411 - 5,138,084 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000060832   ⟹   ENSRNOP00000057557
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl203,675,938 - 3,688,362 (-)Ensembl
Rnor_6.0 Ensembl205,125,679 - 5,138,084 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000085598   ⟹   ENSRNOP00000074143
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl203,675,938 - 3,688,362 (-)Ensembl
Rnor_6.0 Ensembl205,125,349 - 5,138,084 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000097591   ⟹   ENSRNOP00000090281
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl203,675,939 - 3,688,143 (-)Ensembl
RefSeq Acc Id: NM_001033968   ⟹   NP_001029140
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2203,675,938 - 3,688,344 (-)NCBI
Rnor_6.0205,125,679 - 5,138,084 (+)NCBI
Rnor_5.0207,198,613 - 7,211,343 (+)NCBI
RGSC_v3.4203,739,593 - 3,752,311 (-)RGD
Celera204,337,299 - 4,349,704 (+)NCBI
Sequence:
RefSeq Acc Id: NM_053609   ⟹   NP_446061
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2203,675,938 - 3,688,657 (-)NCBI
Rnor_6.0205,125,366 - 5,138,084 (+)NCBI
Rnor_5.0207,198,613 - 7,211,343 (+)NCBI
RGSC_v3.4203,739,593 - 3,752,311 (-)RGD
Celera204,336,986 - 4,349,704 (+)RGD
Sequence:
RefSeq Acc Id: XM_006256082   ⟹   XP_006256144
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2203,675,938 - 3,688,406 (-)NCBI
Rnor_6.0205,125,617 - 5,138,084 (+)NCBI
Rnor_5.0207,198,613 - 7,211,343 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006256083   ⟹   XP_006256145
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2203,675,938 - 3,688,406 (-)NCBI
Rnor_6.0205,125,617 - 5,138,084 (+)NCBI
Rnor_5.0207,198,613 - 7,211,343 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006256084   ⟹   XP_006256146
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2203,675,938 - 3,688,406 (-)NCBI
Rnor_6.0205,125,617 - 5,138,084 (+)NCBI
Rnor_5.0207,198,613 - 7,211,343 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006256086   ⟹   XP_006256148
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2203,675,938 - 3,690,414 (-)NCBI
Rnor_6.0205,124,512 - 5,138,084 (+)NCBI
Rnor_5.0207,198,613 - 7,211,343 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006256087   ⟹   XP_006256149
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2203,675,938 - 3,688,169 (-)NCBI
Rnor_6.0205,125,788 - 5,138,084 (+)NCBI
Rnor_5.0207,198,613 - 7,211,343 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006256088   ⟹   XP_006256150
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2203,675,938 - 3,688,406 (-)NCBI
Rnor_6.0205,125,617 - 5,138,084 (+)NCBI
Rnor_5.0207,198,613 - 7,211,343 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006256089   ⟹   XP_006256151
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2203,675,938 - 3,688,406 (-)NCBI
Rnor_6.0205,125,617 - 5,138,084 (+)NCBI
Rnor_5.0207,198,613 - 7,211,343 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006256090   ⟹   XP_006256152
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2203,675,938 - 3,688,406 (-)NCBI
Rnor_6.0205,125,617 - 5,138,084 (+)NCBI
Rnor_5.0207,198,613 - 7,211,343 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006256091   ⟹   XP_006256153
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2203,676,009 - 3,688,406 (-)NCBI
Rnor_6.0205,125,617 - 5,138,084 (+)NCBI
Rnor_5.0207,198,613 - 7,211,343 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006256092   ⟹   XP_006256154
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2203,675,945 - 3,688,406 (-)NCBI
Rnor_6.0205,125,617 - 5,138,084 (+)NCBI
Rnor_5.0207,198,613 - 7,211,343 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006256093   ⟹   XP_006256155
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2203,675,939 - 3,688,674 (-)NCBI
Rnor_6.0205,125,349 - 5,138,084 (+)NCBI
Rnor_5.0207,198,613 - 7,211,343 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006256094   ⟹   XP_006256156
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2203,676,009 - 3,688,406 (-)NCBI
Rnor_6.0205,125,617 - 5,138,084 (+)NCBI
Rnor_5.0207,198,613 - 7,211,343 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039099133   ⟹   XP_038955061
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2203,675,938 - 3,690,414 (-)NCBI
RefSeq Acc Id: XM_039099135   ⟹   XP_038955063
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2203,676,009 - 3,688,406 (-)NCBI
RefSeq Acc Id: XM_039099136   ⟹   XP_038955064
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2203,675,938 - 3,688,661 (-)NCBI
RefSeq Acc Id: XM_039099137   ⟹   XP_038955065
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2203,675,938 - 3,688,406 (-)NCBI
RefSeq Acc Id: XM_039099138   ⟹   XP_038955066
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2203,676,009 - 3,688,406 (-)NCBI
RefSeq Acc Id: XM_039099139   ⟹   XP_038955067
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2203,676,009 - 3,688,406 (-)NCBI
RefSeq Acc Id: XM_039099140   ⟹   XP_038955068
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2203,676,009 - 3,688,406 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001029140 (Get FASTA)   NCBI Sequence Viewer  
  NP_446061 (Get FASTA)   NCBI Sequence Viewer  
  XP_006256144 (Get FASTA)   NCBI Sequence Viewer  
  XP_006256145 (Get FASTA)   NCBI Sequence Viewer  
  XP_006256146 (Get FASTA)   NCBI Sequence Viewer  
  XP_006256148 (Get FASTA)   NCBI Sequence Viewer  
  XP_006256149 (Get FASTA)   NCBI Sequence Viewer  
  XP_006256150 (Get FASTA)   NCBI Sequence Viewer  
  XP_006256151 (Get FASTA)   NCBI Sequence Viewer  
  XP_006256152 (Get FASTA)   NCBI Sequence Viewer  
  XP_006256153 (Get FASTA)   NCBI Sequence Viewer  
  XP_006256154 (Get FASTA)   NCBI Sequence Viewer  
  XP_006256155 (Get FASTA)   NCBI Sequence Viewer  
  XP_006256156 (Get FASTA)   NCBI Sequence Viewer  
  XP_038955061 (Get FASTA)   NCBI Sequence Viewer  
  XP_038955063 (Get FASTA)   NCBI Sequence Viewer  
  XP_038955064 (Get FASTA)   NCBI Sequence Viewer  
  XP_038955065 (Get FASTA)   NCBI Sequence Viewer  
  XP_038955066 (Get FASTA)   NCBI Sequence Viewer  
  XP_038955067 (Get FASTA)   NCBI Sequence Viewer  
  XP_038955068 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI00142 (Get FASTA)   NCBI Sequence Viewer  
  BAA76607 (Get FASTA)   NCBI Sequence Viewer  
  CAE83997 (Get FASTA)   NCBI Sequence Viewer  
  EDL83534 (Get FASTA)   NCBI Sequence Viewer  
  EDL83536 (Get FASTA)   NCBI Sequence Viewer  
  Q6MG49 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_446061   ⟸   NM_053609
- Peptide Label: isoform 2
- UniProtKB: Q6MG49 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001029140   ⟸   NM_001033968
- Peptide Label: isoform 1
- UniProtKB: Q6MG49 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006256155   ⟸   XM_006256093
- Peptide Label: isoform X17
- UniProtKB: A0A0G2K7C1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006256148   ⟸   XM_006256086
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_006256144   ⟸   XM_006256082
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_006256151   ⟸   XM_006256089
- Peptide Label: isoform X6
- Sequence:
RefSeq Acc Id: XP_006256145   ⟸   XM_006256083
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_006256156   ⟸   XM_006256094
- Peptide Label: isoform X13
- Sequence:
RefSeq Acc Id: XP_006256150   ⟸   XM_006256088
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_006256154   ⟸   XM_006256092
- Peptide Label: isoform X14
- Sequence:
RefSeq Acc Id: XP_006256146   ⟸   XM_006256084
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_006256153   ⟸   XM_006256091
- Peptide Label: isoform X12
- Sequence:
RefSeq Acc Id: XP_006256152   ⟸   XM_006256090
- Peptide Label: isoform X8
- Sequence:
RefSeq Acc Id: XP_006256149   ⟸   XM_006256087
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: ENSRNOP00000057557   ⟸   ENSRNOT00000060832
RefSeq Acc Id: ENSRNOP00000074143   ⟸   ENSRNOT00000085598
RefSeq Acc Id: ENSRNOP00000001129   ⟸   ENSRNOT00000001129
RefSeq Acc Id: XP_038955061   ⟸   XM_039099133
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038955064   ⟸   XM_039099136
- Peptide Label: isoform X9
RefSeq Acc Id: XP_038955065   ⟸   XM_039099137
- Peptide Label: isoform X10
RefSeq Acc Id: XP_038955068   ⟸   XM_039099140
- Peptide Label: isoform X16
RefSeq Acc Id: XP_038955067   ⟸   XM_039099139
- Peptide Label: isoform X15
RefSeq Acc Id: XP_038955066   ⟸   XM_039099138
- Peptide Label: isoform X11
RefSeq Acc Id: XP_038955063   ⟸   XM_039099135
- Peptide Label: isoform X7
RefSeq Acc Id: ENSRNOP00000090281   ⟸   ENSRNOT00000097591
Protein Domains
Ubiquitin-like

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13701402
Promoter ID:EPDNEW_R11920
Type:multiple initiation site
Name:Bag6_1
Description:BCL2-associated athanogene 6
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R11921  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0205,125,362 - 5,125,422EPDNEW
RGD ID:13701398
Promoter ID:EPDNEW_R11921
Type:initiation region
Name:Bag6_2
Description:BCL2-associated athanogene 6
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R11920  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0205,125,666 - 5,125,726EPDNEW

Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN-Lx/CubMcwi (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BUF/N (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
Buf/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
DA/OlaHsd (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
F344/Stm (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FXLE16/Stm (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GH/OmrMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/FarMcwi (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/Ox (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
HXB10/IpcvMcwi (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEXF10A/StmMcwi (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrcAek (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrcAek (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrcAek (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
M520/NRrrcMcwi (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MHS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MWF/Hsd (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SBH/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/OlalpcvMcwi (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/RijCrl (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Damaging Variants


Assembly: Rnor_5.0

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
20 7210840 7210841 C A snv FHL/EurMcwi (MCW), ZF (KyushuU), MHS/Gib (KNAW), MR/N (KNAW), WAG/Rij (KNAW), BBDP/WorN (KNAW), FHL/EurMcwi (KNAW), MNS/Gib (KNAW), SBN/Ygl (KNAW), SDLEF7/Barth (UDEL), LE/OrlBarth (UDEL), BUF/MNa (KyushuU), HTX/Kyo (KyushuU), RCS/Kyo (KyushuU), LEC/Tj (KyushuU), KFRS3B/Kyo (KyushuU), SBN/Ygl (MCW)


Assembly: mRatBN7.2

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
20 3676441 3676442 G T snv WAG/RijCrl (2020), MWF/Hsd (2019)


Assembly: Rnor_6.0

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
20 5129706 5129707 T G snv SR/JrHsd (RGD)
20 5129708 5129709 A G snv SR/JrHsd (RGD)
20 5130765 5130766 A C snv ACI/N (MCW)
20 5132605 5132606 G A snv Buf/N (MCW)
20 5132752 5132753 G A snv WKY/N (MCW), WN/N (MCW), MR/N (MCW), F344/NRrrc (MCW), ACI/N (MCW)
20 5135000 5135001 C T snv WN/N (MCW), MR/N (MCW)
20 5135105 5135106 A G snv WN/N (MCW), WKY/N (MCW), MR/N (MCW), ACI/N (MCW), F344/NRrrc (MCW)
20 5136782 5136783 G A snv WKY/N (MCW), F344/NRrrc (MCW), MR/N (MCW), WN/N (MCW)
20 5137579 5137580 G T snv MR/N (MCW)
20 5137581 5137582 C A snv FHL/EurMcwi (MCW), SBN/Ygl (MCW), BBDP/Wor (RGD), MHS/Gib (RGD), WAG/RijCrl (2020), SBN/Ygl (RGD), WAG/Rij (RGD), MWF/Hsd (2019), MNS/Gib (RGD)


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:71064 AgrOrtholog
BIND 130895
Ensembl Genes ENSRNOG00000000851 Ensembl, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000001129 UniProtKB/Swiss-Prot
  ENSRNOP00000057557 UniProtKB/Swiss-Prot
  ENSRNOP00000074143 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000001129 UniProtKB/Swiss-Prot
  ENSRNOT00000060832 UniProtKB/Swiss-Prot
  ENSRNOT00000085598 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7315623 IMAGE-MGC_LOAD
InterPro BAG6 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ubiquitin-like_dom UniProtKB/TrEMBL
  Ubiquitin-like_domsf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ubiquitin_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ubiquitin_dom UniProtKB/Swiss-Prot
KEGG Report rno:94342 UniProtKB/Swiss-Prot
MGC_CLONE MGC:114288 IMAGE-MGC_LOAD
NCBI Gene 94342 ENTREZGENE
Pfam BAG6 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ubiquitin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Bag6 PhenoGen
PROSITE UBIQUITIN_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  UBIQUITIN_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART UBQ UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF54236 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2K7C1 ENTREZGENE, UniProtKB/TrEMBL
  BAG6_RAT UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary Q498N5 UniProtKB/Swiss-Prot
  Q9WTN8 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-11-11 Bag6  BAG cochaperone 6  Bag6  BCL2-associated athanogene 6  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2011-07-28 Bag6  BCL2-associated athanogene 6  Bat3  HLA-B-associated transcript 3  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2002-07-09 Bat3  HLA-B-associated transcript 3      Symbol and Name updated to reflect Human and Mouse nomenclature 70877 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_expression expressed in all the adult tissues, enriched in testis 70664
gene_homology 87.4% identity with human BAT3 at the amino acid level 70664
gene_mapping found within the rat major histocompatibility RT1 complex 1300431
gene_physical_interaction interacts with with a candidate tumor suppressor, DAN 70664
gene_protein 1098 amino acids 70664