Sag (S-antigen visual arrestin) - Rat Genome Database

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Gene: Sag (S-antigen visual arrestin) Rattus norvegicus
Analyze
Symbol: Sag
Name: S-antigen visual arrestin
RGD ID: 3619
Description: Enables spectrin binding activity. Predicted to be involved in G protein-coupled receptor internalization. Located in photoreceptor inner segment and photoreceptor outer segment. Human ortholog(s) of this gene implicated in Oguchi disease-1; hereditary night blindness; and retinitis pigmentosa 47. Orthologous to human SAG (S-antigen visual arrestin); PARTICIPATES IN altered visual phototransduction pathway; retinitis pigmentosa pathway; visual phototransduction pathway; INTERACTS WITH 2,2',5,5'-tetrachlorobiphenyl; ammonium chloride; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: 48 kDa protein; retina and pineal gland (arrestin); retinal S-antigen; rod photoreceptor arrestin; S-AG; S-antigen; S-antigen; retina and pineal gland (arrestin); S-arrestin; SAGMR; SANTI
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2988,467,797 - 88,508,821 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl988,469,376 - 88,508,820 (+)Ensembl
Rnor_6.0994,926,901 - 94,972,162 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl994,928,489 - 94,972,027 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0994,646,333 - 94,691,522 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4986,759,933 - 86,799,902 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1986,944,774 - 86,983,310 (+)NCBI
Celera985,877,786 - 85,890,904 (+)NCBICelera
Celera254,322,671 - 54,345,084 (-)NCBICelera
Cytogenetic Map9q35NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
membrane  (IEA)
photoreceptor inner segment  (IBA,IDA,IEA,ISO)
photoreceptor outer segment  (IBA,IDA,IEA,ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Additional References at PubMed
PMID:2373176   PMID:3720866   PMID:12486395   PMID:19332500   PMID:22869374  


Genomics

Comparative Map Data
Sag
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2988,467,797 - 88,508,821 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl988,469,376 - 88,508,820 (+)Ensembl
Rnor_6.0994,926,901 - 94,972,162 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl994,928,489 - 94,972,027 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0994,646,333 - 94,691,522 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4986,759,933 - 86,799,902 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1986,944,774 - 86,983,310 (+)NCBI
Celera985,877,786 - 85,890,904 (+)NCBICelera
Celera254,322,671 - 54,345,084 (-)NCBICelera
Cytogenetic Map9q35NCBI
SAG
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382233,307,816 - 233,347,055 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl2233,307,816 - 233,347,055 (+)EnsemblGRCh38hg38GRCh38
GRCh372234,216,462 - 234,255,701 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362233,881,207 - 233,920,440 (+)NCBINCBI36hg18NCBI36
Build 342233,998,492 - 234,037,701NCBI
Celera2227,937,838 - 227,977,217 (+)NCBI
Cytogenetic Map2q37.1NCBI
HuRef2226,017,093 - 226,056,496 (+)NCBIHuRef
CHM1_12234,222,389 - 234,261,775 (+)NCBICHM1_1
Sag
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39187,731,402 - 87,772,880 (+)NCBIGRCm39mm39
GRCm39 Ensembl187,731,402 - 87,772,880 (+)Ensembl
GRCm38187,798,143 - 87,845,158 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl187,803,680 - 87,845,158 (+)EnsemblGRCm38mm10GRCm38
MGSCv37189,700,255 - 89,741,732 (+)NCBIGRCm37mm9NCBIm37
MGSCv36189,634,851 - 89,676,328 (+)NCBImm8
Celera190,761,584 - 90,803,003 (+)NCBICelera
Cytogenetic Map1DNCBI
cM Map144.44NCBI
Sag
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554532,844,925 - 2,878,846 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554532,845,561 - 2,878,342 (-)NCBIChiLan1.0ChiLan1.0
SAG
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12B239,449,910 - 239,487,626 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B239,449,910 - 239,487,537 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v02B120,532,049 - 120,574,914 (+)NCBIMhudiblu_PPA_v0panPan3
SAG
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12544,800,141 - 44,843,580 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2544,812,362 - 44,843,579 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2545,307,685 - 45,338,815 (+)NCBI
ROS_Cfam_1.02545,060,350 - 45,103,430 (+)NCBI
ROS_Cfam_1.0 Ensembl2545,072,284 - 45,103,429 (+)Ensembl
UMICH_Zoey_3.12544,996,643 - 45,027,722 (+)NCBI
UNSW_CanFamBas_1.02544,842,616 - 44,873,724 (+)NCBI
UU_Cfam_GSD_1.02544,997,874 - 45,029,086 (+)NCBI
Sag
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303186,974,069 - 187,007,603 (+)NCBI
SpeTri2.0NW_0049365253,932,118 - 3,965,651 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SAG
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl15133,691,886 - 133,741,798 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.115133,704,975 - 133,741,844 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215147,580,489 - 147,592,533 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Sscrofa10.215147,812,862 - 147,835,188 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SAG
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.110119,343,562 - 119,383,119 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl10119,344,090 - 119,382,983 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604080,120,831 - 80,162,410 (-)NCBIVero_WHO_p1.0
Sag
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248435,837,105 - 5,870,417 (+)NCBIHetGla_female_1.0hetGla2

Position Markers
D9Rat6  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2988,507,055 - 88,507,212 (+)MAPPERmRatBN7.2
Rnor_6.0994,970,397 - 94,970,553NCBIRnor6.0
Rnor_5.0994,689,758 - 94,689,914UniSTSRnor5.0
RGSC_v3.4986,797,847 - 86,798,339RGDRGSC3.4
RGSC_v3.4986,798,138 - 86,798,294UniSTSRGSC3.4
RGSC_v3.1986,981,557 - 86,981,713RGD
Celera254,324,279 - 54,324,435UniSTS
RH 3.4 Map2363.51RGD
RH 3.4 Map2363.51UniSTS
RH 2.0 Map9866.0RGD
SHRSP x BN Map956.8299RGD
FHH x ACI Map959.98RGD
Cytogenetic Map9q35UniSTS
D9Wox29  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2988,501,653 - 88,501,685 (+)MAPPERmRatBN7.2
mRatBN7.2988,501,564 - 88,501,685 (+)MAPPERmRatBN7.2
mRatBN7.2988,501,564 - 88,501,966 (+)MAPPERmRatBN7.2
Rnor_6.0994,964,593 - 94,965,026NCBIRnor6.0
Rnor_6.0994,964,593 - 94,964,713NCBIRnor6.0
Rnor_5.0994,683,954 - 94,684,387UniSTSRnor5.0
Rnor_5.0994,683,954 - 94,684,074UniSTSRnor5.0
RGSC_v3.4986,792,647 - 86,792,767UniSTSRGSC3.4
Celera254,329,806 - 54,329,914UniSTS
Cytogenetic Map9q35UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
724544Uae9Urinary albumin excretion QTL 94.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)925268044114175309Rat
731164Uae25Urinary albumin excretion QTL 253.50.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)925661188100929786Rat
8662828Vetf6Vascular elastic tissue fragility QTL 63.9artery integrity trait (VT:0010639)patent ductus arteriosus score (CMO:0002566)93696235992058970Rat
2290450Scl57Serum cholesterol level QTL 574.15blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)93696235995410867Rat
11353951Bp394Blood pressure QTL 394arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)94464992189649921Rat
12879506Pur33Proteinuria QTL 33total urine protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)94464992189649921Rat
11353957Bmd92Bone mineral density QTL 920.01tibia mineral mass (VT:1000283)volumetric bone mineral density (CMO:0001553)94611419991114199Rat
631656Bp108Blood pressure QTL 1085.970.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)94859825193598251Rat
1578760Cm53Cardiac mass QTL 533.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)956771635101771635Rat
724515Uae16Urinary albumin excretion QTL 168urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)958163035100929646Rat
1300134Bp185Blood pressure QTL 1853.73arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)961381434104821652Rat
1581580Uae34Urinary albumin excretion QTL 34urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)96207227596470995Rat
1578757Pur6Proteinuria QTL 63.30.005total urine protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)96207227596470995Rat
61385Edpm9Estrogen-dependent pituitary mass QTL 93.430.05pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)963869687108869687Rat
731171Glom6Glomerulus QTL 62.80.0003kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)964573531109573531Rat
1354626Bvd1Brain ventricular dilatation QTL 13.730.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)975712843111552878Rat
4889852Pur26Proteinuria QTL 26150.001total urine protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)977813894101597663Rat
7794784Mcs31Mammary carcinoma susceptibility QTL 312.98mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)977813894111552878Rat
2303178Bp334Blood pressure QTL 3343.70.01arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)97927151191616855Rat
2303178Bp334Blood pressure QTL 3343.70.01arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)97927151191616855Rat
2303178Bp334Blood pressure QTL 3343.70.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)97927151191616855Rat
724547Cm21Cardiac mass QTL 212.7heart mass (VT:0007028)calculated heart weight (CMO:0000073)979271511102910209Rat
4889943Bss90Bone structure and strength QTL 904.1tibia area (VT:1000281)tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)98636963192058970Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:23
Count of miRNA genes:22
Interacting mature miRNAs:23
Transcripts:ENSRNOT00000024733
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium
Low 1 6 6 6 6 6
Below cutoff 1 31 18 14 9 14 2 2 26 19 19 11 2

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000024733   ⟹   ENSRNOP00000024733
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl988,469,376 - 88,508,820 (+)Ensembl
Rnor_6.0 Ensembl994,928,516 - 94,972,027 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000085770   ⟹   ENSRNOP00000071579
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl988,469,376 - 88,508,686 (+)Ensembl
Rnor_6.0 Ensembl994,928,516 - 94,972,027 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000087366   ⟹   ENSRNOP00000072320
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl994,928,489 - 94,969,040 (+)Ensembl
RefSeq Acc Id: NM_013023   ⟹   NP_037155
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2988,469,376 - 88,508,820 (+)NCBI
Rnor_6.0994,927,066 - 94,972,161 (+)NCBI
Rnor_5.0994,646,333 - 94,691,522 (+)NCBI
RGSC_v3.4986,759,933 - 86,799,902 (+)RGD
Celera254,322,671 - 54,345,084 (-)NCBI
Celera985,877,786 - 85,890,904 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039083069   ⟹   XP_038938997
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2988,467,797 - 88,508,821 (+)NCBI
Protein Sequences
Protein RefSeqs NP_037155 (Get FASTA)   NCBI Sequence Viewer  
  XP_038938997 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA42107 (Get FASTA)   NCBI Sequence Viewer  
  CAA33412 (Get FASTA)   NCBI Sequence Viewer  
  CAA36076 (Get FASTA)   NCBI Sequence Viewer  
  P15887 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_037155   ⟸   NM_013023
- UniProtKB: P15887 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSRNOP00000024733   ⟸   ENSRNOT00000024733
RefSeq Acc Id: ENSRNOP00000072320   ⟸   ENSRNOT00000087366
RefSeq Acc Id: ENSRNOP00000071579   ⟸   ENSRNOT00000085770
RefSeq Acc Id: XP_038938997   ⟸   XM_039083069
- Peptide Label: isoform X1
Protein Domains
Arrestin_C

Protein Structures
Name Modeller Protein Id AA Range Protein Structure Video
AF-P15887-F1-model_v2 AlphaFold P15887 1-403 view protein structure  

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Strain Variation

Strain Sequence Variants (MRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:3619 AgrOrtholog
BioCyc Gene G2FUF-26832 BioCyc
Ensembl Genes ENSRNOG00000018185 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000024733 UniProtKB/TrEMBL
  ENSRNOP00000071579 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOP00000072320 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000024733 UniProtKB/TrEMBL
  ENSRNOT00000085770 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOT00000087366 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.640 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  2.60.40.840 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Arrestin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Arrestin-like_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Arrestin_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Arrestin_C-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Arrestin_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Arrestin_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_E-set UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:25539 UniProtKB/Swiss-Prot
NCBI Gene 25539 ENTREZGENE
PANTHER PTHR11792 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Arrestin_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Arrestin_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Sag PhenoGen
PRINTS ARRESTIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE ARRESTINS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART Arrestin_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF81296 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TIGR TC218978
UniProt A0A0G2K2P1_RAT UniProtKB/TrEMBL
  ARRS_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  R4GNK4_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-09-26 Sag  S-antigen visual arrestin  Sag  S-antigen  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2015-09-22 Sag  S-antigen  Sag  S-antigen; retina and pineal gland (arrestin)  Name changed 629549 APPROVED
2008-09-18 Sag  S-antigen; retina and pineal gland (arrestin)  Sag  retinal S-antigen  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2002-06-10 Sag  S-antigen      Symbol and Name status set to approved 70586 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_disease mutations of the human homolog are detected in Oguchi disease, a rare autosomal recessive form of congenital stationary night blindness 734491