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Gene: Aldh1l1 (aldehyde dehydrogenase 1 family, member L1) Rattus norvegicus
Symbol: Aldh1l1
Name: aldehyde dehydrogenase 1 family, member L1
RGD ID: 621294
Description: Exhibits aldehyde dehydrogenase (NADP+) activity. Involved in bile acid signaling pathway. Localizes to protein-containing complex. Biomarker of cholestasis. Orthologous to human ALDH1L1 (aldehyde dehydrogenase 1 family member L1); PARTICIPATES IN bile acid signaling pathway; altered folate cycle metabolic pathway; folate cycle metabolic pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran.
Type: protein-coding
Also known as: 10-formyltetrahydrofolate dehydrogenase; 10-FTHFDH; aldehyde dehydrogenase family 1 member L1; cytosolic 10-formyltetrahydrofolate dehydrogenase; FBP-CI; FDH; formyltetrahydrofolate dehydrogenase; Fthfd; MGC105431
Homo sapiens (human) : ALDH1L1 (aldehyde dehydrogenase 1 family member L1)  HGNC  Alliance
Mus musculus (house mouse) : Aldh1l1 (aldehyde dehydrogenase 1 family, member L1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Aldh1l1 (aldehyde dehydrogenase 1 family member L1)
Pan paniscus (bonobo/pygmy chimpanzee) : ALDH1L1 (aldehyde dehydrogenase 1 family member L1)
Canis lupus familiaris (dog) : LOC476506 (cytosolic 10-formyltetrahydrofolate dehydrogenase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Aldh1l1 (aldehyde dehydrogenase 1 family member L1)
Sus scrofa (pig) : ALDH1L1 (aldehyde dehydrogenase 1 family member L1)
Chlorocebus sabaeus (African green monkey) : ALDH1L1 (aldehyde dehydrogenase 1 family member L1)
Heterocephalus glaber (naked mole-rat) : Aldh1l1 (aldehyde dehydrogenase 1 family member L1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.04123,516,553 - 123,564,067 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4123,516,788 - 123,557,501 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04186,990,816 - 187,030,955 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera4111,983,791 - 112,029,897 (+)NCBICelera
Cytogenetic Map4q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Aldh1l1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 621294
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.