Aldh1l1 (aldehyde dehydrogenase 1 family member L1) - Rat Genome Database

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Gene: Aldh1l1 (aldehyde dehydrogenase 1 family member L1) Chinchilla lanigera
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Symbol: Aldh1l1
Name: aldehyde dehydrogenase 1 family member L1
RGD ID: 8727717
Description: ENCODES a protein that exhibits aldehyde dehydrogenase (NADP+) activity (ortholog); aldehyde dehydrogenase [NAD(P)+] activity (ortholog); formyltetrahydrofolate dehydrogenase activity (ortholog); INVOLVED IN 10-formyltetrahydrofolate catabolic process (ortholog); folic acid metabolic process (ortholog); NADPH regeneration (ortholog); PARTICIPATES IN altered folate cycle metabolic pathway; folate cycle metabolic pathway; folate mediated one-carbon metabolic pathway; ASSOCIATED WITH alkaptonuria (ortholog); autism spectrum disorder (ortholog); cholestasis (ortholog); FOUND IN cytosol (ortholog); mitochondrion (ortholog); protein-containing complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: aldehyde dehydrogenase 1 family, member L1; cytosolic 10-formyltetrahydrofolate dehydrogenase
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542121,420,147 - 21,527,037 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542121,420,264 - 21,506,004 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Aldh1l1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542121,420,147 - 21,527,037 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542121,420,264 - 21,506,004 (-)NCBIChiLan1.0ChiLan1.0
ALDH1L1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383126,103,570 - 126,197,945 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3126,103,562 - 126,197,994 (-)EnsemblGRCh38hg38GRCh38
GRCh373125,822,413 - 125,900,029 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 363127,305,098 - 127,382,175 (-)NCBINCBI36Build 36hg18NCBI36
Celera3124,246,087 - 124,323,172 (-)NCBICelera
Cytogenetic Map3q21.3NCBI
HuRef3123,202,976 - 123,280,599 (-)NCBIHuRef
CHM1_13125,785,177 - 125,862,716 (-)NCBICHM1_1
T2T-CHM13v2.03128,835,963 - 128,930,120 (-)NCBIT2T-CHM13v2.0
Aldh1l1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39690,527,751 - 90,576,153 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl690,463,409 - 90,577,185 (+)EnsemblGRCm39 Ensembl
GRCm38690,550,768 - 90,599,171 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl690,486,427 - 90,600,203 (+)EnsemblGRCm38mm10GRCm38
MGSCv37690,500,842 - 90,549,165 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36690,516,352 - 90,564,675 (+)NCBIMGSCv36mm8
Celera692,439,210 - 92,482,963 (+)NCBICelera
Cytogenetic Map6D1NCBI
cM Map640.16NCBI
Aldh1l1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84124,617,182 - 124,663,674 (+)NCBIGRCr8
mRatBN7.24123,059,989 - 123,106,471 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4123,060,008 - 123,106,465 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4128,527,602 - 128,574,093 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04124,302,026 - 124,348,513 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04122,926,598 - 122,973,089 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04123,516,553 - 123,564,067 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4123,516,788 - 123,557,501 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04186,990,816 - 187,030,955 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera4111,983,791 - 112,029,897 (+)NCBICelera
Cytogenetic Map4q34NCBI
ALDH1L1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22124,047,200 - 124,124,841 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13124,051,981 - 124,129,620 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03123,166,630 - 123,244,257 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13130,484,862 - 130,562,958 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3130,484,862 - 130,562,934 (-)Ensemblpanpan1.1panPan2
ALDH1L1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12052,722 - 99,180 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2061,349 - 99,160 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha20318,809 - 429,721 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.020291,997 - 402,986 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl20288,804 - 402,864 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12023,804 - 134,696 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.020354,338 - 463,492 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.020313,350 - 422,524 (-)NCBIUU_Cfam_GSD_1.0
Aldh1l1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494219,186,039 - 19,234,700 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936898456,521 - 484,282 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936898456,299 - 484,681 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ALDH1L1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl753,748,653 - 53,794,706 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1753,748,585 - 53,794,777 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
ALDH1L1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12254,848,868 - 54,933,415 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2254,848,901 - 54,934,629 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041111,375,948 - 111,461,164 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Aldh1l1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624773385,594 - 468,270 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624773385,583 - 468,270 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSCLAT00000007969   ⟹   ENSCLAP00000007849
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495542121,420,147 - 21,527,037 (-)Ensembl
Ensembl Acc Id: ENSCLAT00000007970   ⟹   ENSCLAP00000007850
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495542121,420,147 - 21,506,278 (-)Ensembl
RefSeq Acc Id: XM_005383830   ⟹   XP_005383887
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495542121,420,264 - 21,506,004 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005383887 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000007849
  ENSCLAP00000007849.1
  ENSCLAP00000007850.1
RefSeq Acc Id: XP_005383887   ⟸   XM_005383830
- UniProtKB: A0A8C2V5F9 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCLAP00000007850   ⟸   ENSCLAT00000007970
Ensembl Acc Id: ENSCLAP00000007849   ⟸   ENSCLAT00000007969
Protein Domains
Carrier


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000005505 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000007969 ENTREZGENE
  ENSCLAT00000007969.1 UniProtKB/TrEMBL
  ENSCLAT00000007970.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.1200.10 UniProtKB/TrEMBL
  3.10.25.10 UniProtKB/TrEMBL
  Formyl transferase, N-terminal domain UniProtKB/TrEMBL
InterPro 10_FTHF_DH UniProtKB/TrEMBL
  ACP-like_sf UniProtKB/TrEMBL
  Ald_DH/histidinol_DH UniProtKB/TrEMBL
  Ald_DH_C UniProtKB/TrEMBL
  Ald_DH_CS_CYS UniProtKB/TrEMBL
  Ald_DH_CS_GLU UniProtKB/TrEMBL
  Ald_DH_N UniProtKB/TrEMBL
  Aldehyde_DH_dom UniProtKB/TrEMBL
  Formyl_trans_C UniProtKB/TrEMBL
  Formyl_trans_C_sf UniProtKB/TrEMBL
  Formyl_transf_N UniProtKB/TrEMBL
  Formyl_transf_N_sf UniProtKB/TrEMBL
  Formyl_transferase-like_C_sf UniProtKB/TrEMBL
  GART_AS UniProtKB/TrEMBL
  PP-bd_ACP UniProtKB/TrEMBL
NCBI Gene Aldh1l1 ENTREZGENE
PANTHER ALDEHYDE DEHYDROGENASE-RELATED UniProtKB/TrEMBL
  CYTOSOLIC 10-FORMYLTETRAHYDROFOLATE DEHYDROGENASE UniProtKB/TrEMBL
Pfam Aldedh UniProtKB/TrEMBL
  Formyl_trans_C UniProtKB/TrEMBL
  Formyl_trans_N UniProtKB/TrEMBL
  PP-binding UniProtKB/TrEMBL
PIRSF 10-FTHFDH UniProtKB/TrEMBL
PROSITE ALDEHYDE_DEHYDR_CYS UniProtKB/TrEMBL
  ALDEHYDE_DEHYDR_GLU UniProtKB/TrEMBL
  CARRIER UniProtKB/TrEMBL
  GART UniProtKB/TrEMBL
Superfamily-SCOP SSF47336 UniProtKB/TrEMBL
  SSF50486 UniProtKB/TrEMBL
  SSF53328 UniProtKB/TrEMBL
  SSF53720 UniProtKB/TrEMBL
UniProt A0A8C2V5F9 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-16 Aldh1l1  aldehyde dehydrogenase 1 family member L1    aldehyde dehydrogenase 1 family, member L1  Symbol and/or name change 5135510 APPROVED