1,2-dichloroethane increases expression ISO RGD:10732 6480464 ethylene dichloride results in increased expression of HRH2 mRNA CTD PMID:28960355 1-(5-isoquinolinesulfonyl)-2-methylpiperazine multiple interactions ISO RGD:735725 6480464 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [Dimaprit results in increased expression of HRH2 mRNA] CTD PMID:9187264 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:10732 6480464 Tetrachlorodibenzodioxin affects the expression of HRH2 mRNA CTD PMID:21570461 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of HRH2 mRNA CTD PMID:32109520 3',5'-cyclic AMP multiple interactions ISO RGD:735725 6480464 [Cimetidine binds to and results in decreased activity of HRH2 protein] which results in decreased abundance of Cyclic AMP more ... CTD PMID:15843518 more ... 3',5'-cyclic AMP increases abundance ISO RGD:735725 6480464 HRH2 protein results in increased abundance of Cyclic AMP CTD PMID:9681472 4-methylhistamine multiple interactions ISO RGD:735725 6480464 4-methylhistamine binds to and results in increased activity of HRH2 protein, [4-methylhistamine binds to and results in increased activity of HRH2 protein] which affects the expression of CD14 protein CTD PMID:14499251 5-(2-methylpiperazine-1-sulfonyl)isoquinoline multiple interactions ISO RGD:735725 6480464 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [Dimaprit results in increased expression of HRH2 mRNA] CTD PMID:9187264 6-propyl-2-thiouracil decreases expression EXP 6480464 Propylthiouracil results in decreased expression of HRH2 mRNA CTD PMID:24780913 all-trans-retinoic acid increases expression ISO RGD:735725 6480464 Tretinoin results in increased expression of HRH2 mRNA CTD PMID:33167477 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of HRH2 mRNA CTD PMID:16483693 arsenite(3-) increases expression ISO RGD:10732 6480464 arsenite results in increased expression of HRH2 mRNA CTD PMID:33053406 asbestos increases expression ISO RGD:735725 6480464 Asbestos results in increased expression of HRH2 mRNA CTD PMID:22398240 atrazine affects methylation EXP 6480464 Atrazine affects the methylation of HRH2 gene CTD PMID:28931070 benzo[a]pyrene decreases expression ISO RGD:10732 6480464 Benzo(a)pyrene results in decreased expression of HRH2 mRNA CTD PMID:22228805 benzo[a]pyrene affects methylation ISO RGD:735725 6480464 Benzo(a)pyrene affects the methylation of HRH2 5' UTR, Benzo(a)pyrene affects the methylation of HRH2 promoter CTD PMID:27901495 bisphenol A multiple interactions EXP 6480464 [bisphenol A co-treated with Testosterone] results in decreased expression of HRH2 mRNA CTD PMID:26496021 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of HRH2 mRNA CTD PMID:30816183 , PMID:32528016 bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of HRH2 mRNA CTD PMID:25181051 Burimamide increases expression ISO RGD:735725 6480464 Burimamide results in increased expression of HRH2 protein CTD PMID:9681472 Burimamide multiple interactions ISO RGD:735725 6480464 Burimamide binds to and results in decreased activity of HRH2 protein more ... CTD PMID:9681472 CGP 52608 multiple interactions ISO RGD:735725 6480464 CGP 52608 promotes the reaction [RORA protein binds to HRH2 gene] CTD PMID:28238834 chlorphenamine multiple interactions ISO RGD:10732 6480464 Chlorpheniramine inhibits the reaction [HRH2 results in decreased susceptibility to Morphine] CTD PMID:14569158 cimetidine multiple interactions ISO RGD:735725 6480464 [Cimetidine binds to and results in decreased activity of HRH2 protein] results in decreased susceptibility to [Histamine co-treated with [Oxygen deficiency co-treated with Oxygen]] more ... CTD PMID:12235264 more ... cimetidine decreases activity EXP 6480464 Cimetidine results in decreased activity of HRH2 protein CTD PMID:21276809 cimetidine multiple interactions EXP 6480464 [Cimetidine binds to and results in decreased activity of HRH2 protein] which results in decreased susceptibility to clobenpropit more ... CTD PMID:16488453 more ... cimetidine multiple interactions ISO RGD:10732 6480464 Cimetidine binds to and results in increased activity of HRH2 protein more ... CTD PMID:14569158 , PMID:16723495 cimetidine increases expression ISO RGD:735725 6480464 Cimetidine results in increased expression of HRH2 protein CTD PMID:15961859 clobenpropit multiple interactions ISO RGD:735725 6480464 HRH2 protein promotes the reaction [clobenpropit results in increased expression of IL16 protein] CTD PMID:12235264 clobenpropit multiple interactions EXP 6480464 [Cimetidine binds to and results in decreased activity of HRH2 protein] which results in decreased susceptibility to clobenpropit CTD PMID:16488453 colforsin daropate hydrochloride multiple interactions ISO RGD:735725 6480464 Dimaprit inhibits the reaction [HRH2 protein promotes the reaction [Colforsin results in increased abundance of Cyclic AMP]], HRH2 protein promotes the reaction [Colforsin results in increased abundance of Cyclic AMP] CTD PMID:9187264 cyclosporin A increases methylation ISO RGD:735725 6480464 Cyclosporine results in increased methylation of HRH2 promoter CTD PMID:27989131 D-mannitol increases expression ISO RGD:10732 6480464 Mannitol results in increased expression of HRH2 mRNA CTD PMID:25270620 Dimaprit multiple interactions ISO RGD:10732 6480464 Dimaprit binds to and results in increased activity of HRH2 protein, HRH2 protein promotes the reaction [Dimaprit results in increased expression of IL6 mRNA] CTD PMID:9657254 Dimaprit multiple interactions EXP 6480464 Dimaprit binds to and results in increased activity of HRH2 protein, Ranitidine inhibits the reaction [Dimaprit binds to and results in increased activity of HRH2 protein] CTD PMID:16143415 Dimaprit increases activity EXP 6480464 Dimaprit results in increased activity of HRH2 protein CTD PMID:21276809 Dimaprit multiple interactions ISO RGD:735725 6480464 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [Dimaprit results in increased expression of HRH2 mRNA] more ... CTD PMID:12235264 more ... dioxygen multiple interactions ISO RGD:735725 6480464 [Cimetidine binds to and results in decreased activity of HRH2 protein] results in decreased susceptibility to [Histamine co-treated with [Oxygen deficiency co-treated with Oxygen]] CTD PMID:22926047 doxorubicin decreases expression ISO RGD:735725 6480464 Doxorubicin results in decreased expression of HRH2 mRNA CTD PMID:29803840 ethanol affects expression ISO RGD:10732 6480464 Ethanol affects the expression of HRH2 mRNA CTD PMID:30319688 famotidine multiple interactions ISO RGD:735725 6480464 [Famotidine binds to and results in decreased activity of HRH2 protein] which affects the susceptibility to Metformin more ... CTD PMID:16632449 more ... famotidine decreases activity EXP 6480464 Famotidine results in decreased activity of HRH2 protein CTD PMID:21276809 famotidine multiple interactions EXP 6480464 [Famotidine binds to and results in decreased activity of HRH2 protein] which affects the susceptibility to Histamine CTD PMID:12832840 famotidine increases expression ISO RGD:735725 6480464 Famotidine results in increased expression of HRH2 protein CTD PMID:15961859 fenvalerate increases expression EXP 6480464 fenvalerate results in increased expression of HRH2 mRNA CTD PMID:30307764 fonofos increases methylation ISO RGD:735725 6480464 Fonofos results in increased methylation of HRH2 promoter CTD PMID:22847954 furan decreases expression EXP 6480464 furan results in decreased expression of HRH2 mRNA CTD PMID:25539665 histamine multiple interactions ISO RGD:735725 6480464 [Cimetidine binds to and results in decreased activity of HRH2 protein] results in decreased susceptibility to [Histamine co-treated with [Oxygen deficiency co-treated with Oxygen]] more ... CTD PMID:10569698 more ... histamine multiple interactions EXP 6480464 [[thioperamide results in increased abundance of Histamine] which results in increased activity of HRH2 protein] which results in decreased susceptibility to Scopolamine more ... CTD PMID:11640976 more ... histamine multiple interactions ISO RGD:10732 6480464 HRH2 protein affects the reaction [Histamine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG protein]] more ... CTD PMID:16723495 , PMID:19277450 histamine increases activity ISO RGD:735725 6480464 Histamine results in increased activity of HRH2 protein CTD PMID:15843518 histamine affects localization ISO RGD:735725 6480464 Histamine affects the localization of HRH2 protein CTD PMID:15961859 histamine affects expression ISO RGD:735725 6480464 Histamine affects the expression of HRH2 protein CTD PMID:9681472 ionomycin multiple interactions ISO RGD:10732 6480464 HRH2 protein affects the reaction [Histamine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG protein]] more ... CTD PMID:19277450 lipopolysaccharide multiple interactions ISO RGD:735725 6480464 [S-(1 more ... CTD PMID:10569698 , PMID:35811015 melittin increases activity EXP 6480464 Melitten results in increased activity of HRH2 protein CTD PMID:22995146 melittin multiple interactions EXP 6480464 Ranitidine inhibits the reaction [Melitten results in increased activity of HRH2 protein] CTD PMID:22995146 melittin increases response to substance EXP 6480464 HRH2 protein results in increased susceptibility to Melitten CTD PMID:22995146 metformin multiple interactions ISO RGD:735725 6480464 [Cimetidine binds to and results in decreased activity of HRH2 protein] which affects the susceptibility to Metformin more ... CTD PMID:16632449 morphine multiple interactions ISO RGD:10732 6480464 [zolantidine binds to and results in decreased activity of HRH2 protein] which results in increased susceptibility to Morphine more ... CTD PMID:14569158 , PMID:16806305 morphine decreases response to substance ISO RGD:10732 6480464 HRH2 protein results in decreased susceptibility to Morphine, HRH2 results in decreased susceptibility to Morphine CTD PMID:14569158 , PMID:16806305 N-alpha-Methylhistamine multiple interactions EXP 6480464 N-methylhistamine inhibits the reaction [tiotidine binds to HRH2 protein] CTD PMID:12010879 N-alpha-Methylhistamine multiple interactions ISO RGD:735725 6480464 N-methylhistamine binds to and results in increased activity of HRH2 protein CTD PMID:12010879 N1'-[2-[[5-[(dimethylamino)methyl]-2-furanyl]methylthio]ethyl]-N1-methyl-2-nitroethene-1,1-diamine multiple interactions ISO RGD:735725 6480464 [Ranitidine binds to and results in decreased activity of HRH2 protein] which affects the susceptibility to Metformin more ... CTD PMID:11527950 more ... N1'-[2-[[5-[(dimethylamino)methyl]-2-furanyl]methylthio]ethyl]-N1-methyl-2-nitroethene-1,1-diamine decreases activity EXP 6480464 Ranitidine results in decreased activity of HRH2 protein CTD PMID:22995146 N1'-[2-[[5-[(dimethylamino)methyl]-2-furanyl]methylthio]ethyl]-N1-methyl-2-nitroethene-1,1-diamine multiple interactions EXP 6480464 Ranitidine binds to and results in decreased activity of HRH2 protein more ... CTD PMID:16143415 , PMID:22995146 N1'-[2-[[5-[(dimethylamino)methyl]-2-furanyl]methylthio]ethyl]-N1-methyl-2-nitroethene-1,1-diamine decreases activity ISO RGD:735725 6480464 Ranitidine results in decreased activity of HRH2 protein CTD PMID:14671421 naphthalene decreases expression ISO RGD:10732 6480464 naphthalene results in decreased expression of HRH2 mRNA CTD PMID:18757308 parathion increases methylation ISO RGD:735725 6480464 Parathion results in increased methylation of HRH2 promoter CTD PMID:22847954 phorbol 13-acetate 12-myristate multiple interactions ISO RGD:10732 6480464 HRH2 protein affects the reaction [Histamine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG protein]] more ... CTD PMID:19277450 pirinixic acid increases expression EXP 6480464 pirinixic acid results in increased expression of HRH2 mRNA CTD PMID:19162173 promethazine multiple interactions ISO RGD:735725 6480464 Promethazine binds to and results in decreased activity of HRH2 protein CTD PMID:1377455 prostaglandin E2 multiple interactions ISO RGD:735725 6480464 Dimaprit inhibits the reaction [HRH2 protein promotes the reaction [Dinoprostone results in increased abundance of Cyclic AMP]], HRH2 protein promotes the reaction [Dinoprostone results in increased abundance of Cyclic AMP] CTD PMID:9187264 ranitidine multiple interactions ISO RGD:735725 6480464 [Ranitidine binds to and results in decreased activity of HRH2 protein] which affects the susceptibility to Metformin more ... CTD PMID:11527950 more ... ranitidine decreases activity EXP 6480464 Ranitidine results in decreased activity of HRH2 protein CTD PMID:22995146 ranitidine decreases activity ISO RGD:735725 6480464 Ranitidine results in decreased activity of HRH2 protein CTD PMID:14671421 ranitidine multiple interactions EXP 6480464 Ranitidine binds to and results in decreased activity of HRH2 protein more ... CTD PMID:16143415 , PMID:22995146 Roxane multiple interactions EXP 6480464 [roxatidine acetate binds to and results in decreased activity of HRH2 protein] which affects the susceptibility to Histamine CTD PMID:12832840 S-(1,2-dichlorovinyl)-L-cysteine multiple interactions ISO RGD:735725 6480464 [S-(1, 2-dichlorovinyl)cysteine co-treated with Lipopolysaccharides] results in decreased expression of HRH2 mRNA CTD PMID:35811015 scopolamine multiple interactions EXP 6480464 [[thioperamide results in increased abundance of Histamine] which results in increased activity of HRH2 protein] which results in decreased susceptibility to Scopolamine, Cimetidine inhibits the reaction [[Histamine binds to and results in increased activity of HRH2 protein] which results in decreased susceptibility to Scopolamine] CTD PMID:11640976 , PMID:19215234 sodium arsenite decreases expression ISO RGD:735725 6480464 sodium arsenite results in decreased expression of HRH2 mRNA CTD PMID:17879257 terbufos increases methylation ISO RGD:735725 6480464 terbufos results in increased methylation of HRH2 promoter CTD PMID:22847954 testosterone multiple interactions EXP 6480464 [bisphenol A co-treated with Testosterone] results in decreased expression of HRH2 mRNA CTD PMID:26496021 Thioperamide multiple interactions EXP 6480464 [[thioperamide results in increased abundance of Histamine] which results in increased activity of HRH2 protein] which results in decreased susceptibility to Scopolamine more ... CTD PMID:11640976 triclosan decreases expression ISO RGD:735725 6480464 Triclosan results in decreased expression of HRH2 mRNA CTD PMID:30510588 valproic acid increases methylation ISO RGD:735725 6480464 Valproic Acid results in increased methylation of HRH2 gene CTD PMID:29154799
