Gene: Hrh2 (histamine receptor H 2) Rattus norvegicus
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Symbol: Hrh2
Name: histamine receptor H 2
Description: Exhibits heterocyclic compound binding activity and histamine receptor activity; involved in cellular response to histamine and negative regulation of arachidonic acid secretion; localizes to the membrane; biomarker of transient cerebral ischemia; orthologous to human HRH2 (histamine receptor H2); PARTICIPATES IN cimetidine pharmacodynamics pathway; cimetidine pharmacokinetics pathway; esomeprazole pharmacodynamics pathway; INTERACTS WITH 6-propyl-2-thiouracil; acetic acid [2-oxo-2-[3-[3-(1-piperidinylmethyl)phenoxy]propylamino]ethyl] ester; ammonium chloride.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: gastric receptor I; H2R; HH2R; histamine H2 receptor
Orthologs:
Homo sapiens (human) : HRH2 (histamine receptor H2)  HGNC  Alliance
Mus musculus (house mouse) : Hrh2 (histamine receptor H2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hrh2 (histamine receptor H2)
Pan paniscus (bonobo/pygmy chimpanzee) : HRH2 (histamine receptor H2)
Canis lupus familiaris (dog) : HRH2 (histamine receptor H2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hrh2 (histamine receptor H2)
Sus scrofa (pig) : HRH2 (histamine receptor H2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01710,912,959 - 10,931,389 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01713,025,894 - 13,065,409 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41716,497,967 - 16,499,043 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11716,497,966 - 16,499,043 (-)NCBI
Celera1710,455,208 - 10,456,284 (-)NCBICelera
Cytogenetic Map17p14NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model

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Gene Ontology Annotations
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References - curated
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RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
  
More on Hrh2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2831
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.