 Gene-Chemical Interaction Annotations | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Gene Ontology AnnotationsMolecular Pathway Annotations |
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Analyze GeneStrainQTL List |
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Gene Annotator (Annotation Comparison) |
OLGA (Gene List Generator) |
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MOET (Multi-Ontology Enrichement) |
GOLF (Gene-Ortholog Location Finder) |
Gene Ontology AnnotationsMolecular Pathway AnnotationsDisease AnnotationsGene-Chemical Interaction Annotations
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Gene Ontology AnnotationsBiological Process
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Cellular Component
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Molecular Function
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Molecular Pathway AnnotationsReferences - curated| 1. | Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27. |
| 2. | GOA data from the GO Consortium |
| 3. | MGD data from the GO Consortium |
| 4. | Pipeline to import KEGG annotations from KEGG into RGD |
| 5. | RGD automated data pipeline |
| 6. | RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations |
| 7. | RGD automated import pipeline for gene-chemical interactions |
References - uncuratedGenomics
Comparative Map Data| Psmd8 (Rattus norvegicus - Norway rat) |
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| PSMD8 (Homo sapiens - human) |
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| Psmd8 (Mus musculus - house mouse) |
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| Psmd8 (Chinchilla lanigera - long-tailed chinchilla) |
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| PSMD8 (Pan paniscus - bonobo/pygmy chimpanzee) |
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| PSMD8 (Canis lupus familiaris - dog) |
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| Psmd8 (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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| PSMD8 (Sus scrofa - pig) |
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Position Markers| RH131189 |
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| RH124225 |
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QTLs in Region (Rnor_6.0)| The following QTLs overlap with this region. |  | Full Report | | CSV | | TAB | | Printer | | Gviewer |
miRNA Target Status
Predicted Target Of
| The detailed report is available here: | | Full Report | | CSV | | TAB | | Printer |
miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/). For more information about miRGate, see PMID:25858286 or access the full paper here. |
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Expression
RNA-SEQ ExpressionHigh: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM
| testis | heart | brain | ovary | uterus | skeletal muscle tissue | colon | gastrocnemius | forebrain | hindbrain | lung | spleen | liver | kidney | adrenal gland | thymus | |
| High | ||||||||||||||||
| Medium | 22 | 43 | 23 | 15 | 4 | 3 | 3 | 8 | 26 | 25 | 11 | 11 | 41 | 35 | 8 | 8 |
| Low | ||||||||||||||||
| Below cutoff |
View RNA-SEQ Expression Data
Sequence
Nucleotide Sequences| RefSeq Transcripts | NM_001100831 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
| GenBank Nucleotide | AAHX01004480 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
| AAHX01004481 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AC118147 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| BC105894 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| CD371338 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| CH473979 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| CK844749 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| FQ213223 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| FQ214314 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| FQ223219 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| FQ233693 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
Reference Sequences
| RefSeq Acc Id: | ENSRNOT00000027937 ⟹ ENSRNOP00000027937 | |||||||||
| RefSeq Status: | ||||||||||
| Type: | CODING | |||||||||
| Position: |
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| RefSeq Acc Id: | NM_001100831 ⟹ NP_001094301 | ||||||||||||||||||||||||
| RefSeq Status: | VALIDATED | ||||||||||||||||||||||||
| Type: | CODING | ||||||||||||||||||||||||
| Position: |
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| Sequence: |
TTTTGAATGACAACAGAGGCGGAGCTGTGGCATGTTCATTAAGGGCCGGACTGCGAAGGCGCCChide sequence |
Protein Sequences| Protein RefSeqs | NP_001094301 | (Get FASTA) | NCBI Sequence Viewer |
| GenBank Protein | AAI05895 | (Get FASTA) | NCBI Sequence Viewer |
| EDM07842 | (Get FASTA) | NCBI Sequence Viewer | |
| EDM07843 | (Get FASTA) | NCBI Sequence Viewer | |
| EDM07844 | (Get FASTA) | NCBI Sequence Viewer |
Reference Sequences
| RefSeq Acc Id: | NP_001094301 ⟸ NM_001100831 |
| - UniProtKB: | F1LMQ3 (UniProtKB/TrEMBL), Q3B8P5 (UniProtKB/TrEMBL) |
| - Sequence: |
MFIKGRTAKAPRGEPRRSSRRGQKLAVVAPPPALGSTSRPHFRRESIARRRCRKSGRLFAASRKhide sequence |
| RefSeq Acc Id: | ENSRNOP00000027937 ⟸ ENSRNOT00000027937 |
Protein Domains
PCI
TranscriptomeStrain Variation
Strain Sequence Variants (Rnor 6.0)
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Damaging VariantsAssembly: RGSC_v3.4
| Chromosome | Start Pos | End Pos | Reference Nucleotide | Variant Nucleotide | Variant Type | Strain |
| 1 | 84313612 | 84313613 | A | T | snv | FHL/EurMcwi (MCW) |
Additional Information
External Database Links| Database | Acc Id | Source(s) |
| AGR Gene | RGD:1309842 | AgrOrtholog |
| Ensembl Genes | ENSRNOG00000037580 | Ensembl, ENTREZGENE, UniProtKB/TrEMBL |
| Ensembl Protein | ENSRNOP00000027937 | ENTREZGENE, UniProtKB/TrEMBL |
| Ensembl Transcript | ENSRNOT00000027937 | ENTREZGENE, UniProtKB/TrEMBL |
| IMAGE_CLONE | IMAGE:7321643 | IMAGE-MGC_LOAD |
| InterPro | 26S_Psome_Rpn12 | UniProtKB/TrEMBL |
| CSN8_PSD8_EIF3K | UniProtKB/TrEMBL | |
| PCI_dom | UniProtKB/TrEMBL | |
| KEGG Report | rno:292766 | UniProtKB/TrEMBL |
| MGC_CLONE | MGC:125165 | IMAGE-MGC_LOAD |
| NCBI Gene | 292766 | ENTREZGENE |
| PANTHER | Nin1_C | UniProtKB/TrEMBL |
| Pfam | CSN8_PSD8_EIF3K | UniProtKB/TrEMBL |
| PhenoGen | Psmd8 | PhenoGen |
| PROSITE | PCI | UniProtKB/TrEMBL |
| UniGene | Rn.137673 | ENTREZGENE |
| UniProt | F1LMQ3 | ENTREZGENE, UniProtKB/TrEMBL |
| Q3B8P5 | ENTREZGENE, UniProtKB/TrEMBL |
Nomenclature History| Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
|---|---|---|---|---|---|---|---|
| 2015-08-19 | Psmd8 | proteasome 26S subunit, non-ATPase 8 | Psmd8 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
| 2005-12-06 | Psmd8 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 | Psmd8_predicted | proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 (predicted) | Symbol and Name updated | 1559027 | APPROVED |
| 2005-01-12 | Psmd8_predicted | proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 (predicted) | Symbol and Name status set to approved | 70820 | APPROVED |
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| More on Psmd8 | |
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Alliance Gene |
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NCBI Gene |
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Ensembl Gene |
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JBrowse: rn5 rn6 |
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NCBI Genome Data Viewer |
| RGD Object Information | |
| RGD ID: | 1309842 |
| Created: | 2005-01-12 |
| Species: | Rattus norvegicus |
| Last Modified: | 2019-11-27 |
| Status: | ACTIVE |
