Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,2-dimethylhydrazine | decreases expression | ISO | Srek1ip1 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of SREK1IP1 mRNA | CTD | PMID:22206623 | 1,2-dimethylhydrazine | multiple interactions | ISO | Srek1ip1 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of SREK1IP1 mRNA | CTD | PMID:22206623 | 17beta-estradiol | affects expression | ISO | SREK1IP1 (Homo sapiens) | 6480464 | Estradiol affects the expression of SREK1IP1 mRNA | CTD | PMID:22574217 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Srek1ip1 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to SREK1IP1 promoter] | CTD | PMID:19654925 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of SREK1IP1 mRNA | CTD | PMID:33387578 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Srek1ip1 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of SREK1IP1 mRNA | CTD | PMID:21570461 | aflatoxin B1 | decreases methylation | ISO | SREK1IP1 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of SREK1IP1 gene | CTD | PMID:27153756 | all-trans-retinoic acid | decreases expression | ISO | SREK1IP1 (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of SREK1IP1 mRNA | CTD | PMID:21934132 | amiodarone | increases expression | ISO | SREK1IP1 (Homo sapiens) | 6480464 | Amiodarone results in increased expression of SREK1IP1 mRNA | CTD | PMID:19774075 | benzo[a]pyrene | increases methylation | ISO | Srek1ip1 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased methylation of SREK1IP1 exon and Benzo(a)pyrene results in increased methylation of SREK1IP1 intron | CTD | PMID:27901495 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of SREK1IP1 mRNA | CTD | PMID:25181051 | bisphenol A | decreases expression | ISO | Srek1ip1 (Mus musculus) | 6480464 | bisphenol A results in decreased expression of SREK1IP1 mRNA | CTD | PMID:30245210 and PMID:33221593 | bisphenol A | decreases methylation | ISO | Srek1ip1 (Mus musculus) | 6480464 | bisphenol A results in decreased methylation of SREK1IP1 promoter | CTD | PMID:27312807 | bisphenol A | increases methylation | ISO | Srek1ip1 (Mus musculus) | 6480464 | bisphenol A results in increased methylation of SREK1IP1 promoter | CTD | PMID:27312807 | butanal | decreases expression | ISO | SREK1IP1 (Homo sapiens) | 6480464 | butyraldehyde results in decreased expression of SREK1IP1 mRNA | CTD | PMID:26079696 | caffeine | decreases phosphorylation | ISO | SREK1IP1 (Homo sapiens) | 6480464 | Caffeine results in decreased phosphorylation of SREK1IP1 protein | CTD | PMID:35688186 | calcitriol | increases expression | ISO | SREK1IP1 (Homo sapiens) | 6480464 | Calcitriol results in increased expression of SREK1IP1 mRNA | CTD | PMID:16002434 | cobalt dichloride | increases expression | ISO | Srek1ip1 (Mus musculus) | 6480464 | cobaltous chloride results in increased expression of SREK1IP1 mRNA | CTD | PMID:21139344 | copper(II) sulfate | increases expression | ISO | SREK1IP1 (Homo sapiens) | 6480464 | Copper Sulfate results in increased expression of SREK1IP1 mRNA | CTD | PMID:19549813 | cyclophosphamide | increases expression | EXP | | 6480464 | Cyclophosphamide results in increased expression of SREK1IP1 mRNA | CTD | PMID:27281708 | cyclosporin A | decreases expression | ISO | SREK1IP1 (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of SREK1IP1 mRNA | CTD | PMID:25562108 | dicrotophos | decreases expression | ISO | SREK1IP1 (Homo sapiens) | 6480464 | dicrotophos results in decreased expression of SREK1IP1 mRNA | CTD | PMID:28302478 | disodium selenite | increases expression | ISO | SREK1IP1 (Homo sapiens) | 6480464 | Sodium Selenite results in increased expression of SREK1IP1 mRNA | CTD | PMID:18175754 | dorsomorphin | multiple interactions | ISO | SREK1IP1 (Homo sapiens) | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | entinostat | decreases expression | ISO | SREK1IP1 (Homo sapiens) | 6480464 | entinostat results in decreased expression of SREK1IP1 mRNA | CTD | PMID:26272509 | entinostat | multiple interactions | ISO | SREK1IP1 (Homo sapiens) | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SREK1IP1 mRNA | CTD | PMID:27188386 | epoxiconazole | increases expression | ISO | Srek1ip1 (Mus musculus) | 6480464 | epoxiconazole results in increased expression of SREK1IP1 mRNA | CTD | PMID:35436446 | ethanol | affects expression | ISO | Srek1ip1 (Mus musculus) | 6480464 | Ethanol affects the expression of SREK1IP1 mRNA | CTD | PMID:30319688 | flutamide | increases expression | EXP | | 6480464 | Flutamide results in increased expression of SREK1IP1 mRNA | CTD | PMID:24136188 | folic acid | multiple interactions | ISO | Srek1ip1 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of SREK1IP1 mRNA | CTD | PMID:22206623 | formaldehyde | decreases expression | ISO | SREK1IP1 (Homo sapiens) | 6480464 | Formaldehyde results in decreased expression of SREK1IP1 mRNA | CTD | PMID:23649840 | gentamycin | decreases expression | EXP | | 6480464 | Gentamicins results in decreased expression of SREK1IP1 mRNA | CTD | PMID:33387578 | glutathione | decreases expression | EXP | | 6480464 | Glutathione deficiency results in decreased expression of SREK1IP1 mRNA | CTD | PMID:20621112 | gold atom | decreases expression | ISO | SREK1IP1 (Homo sapiens) | 6480464 | Gold results in decreased expression of SREK1IP1 mRNA | CTD | PMID:25523186 | gold(0) | decreases expression | ISO | SREK1IP1 (Homo sapiens) | 6480464 | Gold results in decreased expression of SREK1IP1 mRNA | CTD | PMID:25523186 | methapyrilene | decreases expression | EXP | | 6480464 | Methapyrilene results in decreased expression of SREK1IP1 mRNA | CTD | PMID:30467583 | methyl methanesulfonate | increases expression | ISO | SREK1IP1 (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in increased expression of SREK1IP1 mRNA | CTD | PMID:23649840 | okadaic acid | increases expression | ISO | Srek1ip1 (Mus musculus) | 6480464 | Okadaic Acid results in increased expression of SREK1IP1 mRNA | CTD | PMID:25270620 | ozone | multiple interactions | ISO | Srek1ip1 (Mus musculus) | 6480464 | [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in increased expression of SREK1IP1 mRNA | CTD | PMID:34911549 | paracetamol | affects expression | ISO | Srek1ip1 (Mus musculus) | 6480464 | Acetaminophen affects the expression of SREK1IP1 mRNA | CTD | PMID:17562736 | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of SREK1IP1 mRNA | CTD | PMID:33387578 | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Srek1ip1 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Pectins] results in increased expression of SREK1IP1 mRNA | CTD | PMID:36331819 | phenylmercury acetate | decreases expression | ISO | SREK1IP1 (Homo sapiens) | 6480464 | Phenylmercuric Acetate results in decreased expression of SREK1IP1 mRNA | CTD | PMID:26272509 | phenylmercury acetate | multiple interactions | ISO | SREK1IP1 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SREK1IP1 mRNA | CTD | PMID:27188386 | pirinixic acid | multiple interactions | ISO | Srek1ip1 (Mus musculus) | 6480464 | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of SREK1IP1 mRNA | CTD | PMID:19710929 | SB 431542 | multiple interactions | ISO | SREK1IP1 (Homo sapiens) | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | sodium arsenite | decreases expression | ISO | SREK1IP1 (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of SREK1IP1 mRNA | CTD | PMID:22714537 | trichloroethene | decreases expression | EXP | | 6480464 | Trichloroethylene results in decreased expression of SREK1IP1 mRNA | CTD | PMID:33387578 | trichostatin A | decreases expression | ISO | SREK1IP1 (Homo sapiens) | 6480464 | trichostatin A results in decreased expression of SREK1IP1 mRNA | CTD | PMID:26272509 | trichostatin A | multiple interactions | ISO | SREK1IP1 (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SREK1IP1 mRNA | CTD | PMID:27188386 | valproic acid | affects expression | ISO | SREK1IP1 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of SREK1IP1 mRNA | CTD | PMID:25979313 | valproic acid | multiple interactions | ISO | SREK1IP1 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SREK1IP1 mRNA | CTD | PMID:27188386 | valproic acid | decreases expression | ISO | SREK1IP1 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of SREK1IP1 mRNA | CTD | PMID:23179753 more ... | |