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Gene: Hif3a (hypoxia inducible factor 3 subunit alpha) Rattus norvegicus
Symbol: Hif3a
Name: hypoxia inducible factor 3 subunit alpha
Description: Exhibits DNA-binding transcription factor activity. Involved in positive regulation of transcription by RNA polymerase II. Localizes to cytoplasm and nucleus. Biomarker of pulmonary hypertension. Orthologous to human HIF3A (hypoxia inducible factor 3 subunit alpha); PARTICIPATES IN hypoxia inducible factor pathway; INTERACTS WITH 17beta-estradiol; 6-propyl-2-thiouracil; ammonium chloride.
Type: protein-coding
Also known as: HIF-3 alpha; HIF-3-alpha; HIF3 alpha 1; HIF3-alpha; HIF3-alpha-1; hypoxia inducible factor 3 alpha; hypoxia inducible factor 3 alpha subunit; hypoxia inducible factor 3, alpha subunit; hypoxia inducible factor 3a; hypoxia-inducible factor 3 alpha; hypoxia-inducible factor 3-alpha; Inhibitory PAS (Per/Arnt/Sim) domain protein; Ipas; MOP7
Homo sapiens (human) : HIF3A (hypoxia inducible factor 3 subunit alpha)  HGNC  Alliance
Mus musculus (house mouse) : Hif3a (hypoxia inducible factor 3, alpha subunit)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hif3a (hypoxia inducible factor 3 subunit alpha)
Pan paniscus (bonobo/pygmy chimpanzee) : HIF3A (hypoxia inducible factor 3 subunit alpha)
Canis lupus familiaris (dog) : HIF3A (hypoxia inducible factor 3 subunit alpha)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hif3a (hypoxia inducible factor 3 subunit alpha)
Sus scrofa (pig) : HIF3A (hypoxia inducible factor 3 subunit alpha)
Chlorocebus sabaeus (African green monkey) : HIF3A (hypoxia inducible factor 3 subunit alpha)
Heterocephalus glaber (naked mole-rat) : Hif3a (hypoxia inducible factor 3 subunit alpha)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0178,976,318 - 78,997,869 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl178,976,318 - 78,997,869 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0180,223,828 - 80,245,130 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4177,377,465 - 77,408,704 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1177,455,581 - 77,486,815 (-)NCBI
Celera172,207,606 - 72,229,353 (-)NCBICelera
Cytogenetic Map1q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Hif3a
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 70332
Created: 2002-03-15
Species: Rattus norvegicus
Last Modified: 2020-07-28
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.