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Gene: Tet2 (tet methylcytosine dioxygenase 2) Rattus norvegicus
Symbol: Tet2
Name: tet methylcytosine dioxygenase 2
RGD ID: 1311625
Description: Predicted to have ferrous iron binding activity; methylcytosine dioxygenase activity; and zinc ion binding activity. Involved in response to organic cyclic compound. Predicted to localize to nucleus. Human ortholog(s) of this gene implicated in acute myeloid leukemia; chronic myelomonocytic leukemia; myelodysplastic syndrome; and myeloproliferative neoplasm. Orthologous to human TET2 (tet methylcytosine dioxygenase 2); PARTICIPATES IN DNA modification pathway; INTERACTS WITH acrylamide; arsenous acid; bisphenol A.
Type: protein-coding
RefSeq Status: MODEL
Also known as: LOC310859; methylcytosine dioxygenase TET2; probable methylcytosine dioxygenase TET2; RGD1311625; similar to KIAA1546 protein; tet oncogene family member 2
Homo sapiens (human) : TET2 (tet methylcytosine dioxygenase 2)  HGNC  Alliance
Mus musculus (house mouse) : Tet2 (tet methylcytosine dioxygenase 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tet2 (tet methylcytosine dioxygenase 2)
Pan paniscus (bonobo/pygmy chimpanzee) : TET2 (tet methylcytosine dioxygenase 2)
Canis lupus familiaris (dog) : TET2 (tet methylcytosine dioxygenase 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tet2 (tet methylcytosine dioxygenase 2)
Sus scrofa (pig) : TET2 (tet methylcytosine dioxygenase 2)
Chlorocebus sabaeus (African green monkey) : TET2 (tet methylcytosine dioxygenase 2)
Heterocephalus glaber (naked mole-rat) : Tet2 (tet methylcytosine dioxygenase 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.02238,719,389 - 238,802,975 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2238,720,835 - 238,803,024 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02257,252,323 - 257,335,750 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42231,016,023 - 231,039,777 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12231,002,809 - 231,063,981 (-)NCBI
Celera2214,215,516 - 214,299,103 (-)NCBICelera
Cytogenetic Map2q43NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Tet2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1311625
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.