(-)-epigallocatechin 3-gallate multiple interactions ISO RGD:1606790 6480464 [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of TET2 mRNA CTD PMID:22079256 1,1-dichloroethene decreases expression ISO RGD:1323180 6480464 vinylidene chloride results in decreased expression of TET2 mRNA CTD PMID:26682919 17beta-estradiol decreases expression ISO RGD:1606790 6480464 Estradiol results in decreased expression of TET2 mRNA, Estradiol results in decreased expression of TET2 protein CTD PMID:32105160 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:1606790 6480464 Tetrachlorodibenzodioxin results in increased expression of TET2 mRNA CTD PMID:21632981 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of TET2 mRNA CTD PMID:33387578 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:1606790 6480464 Tetrachlorodibenzodioxin affects the expression of TET2 mRNA CTD PMID:22574217 4,4'-sulfonyldiphenol multiple interactions ISO RGD:1606790 6480464 bis(4-hydroxyphenyl)sulfone promotes the reaction [TET2 protein results in increased abundance of 5-hydroxymethylcytosine] more ... CTD PMID:32105160 4,4'-sulfonyldiphenol increases expression ISO RGD:1606790 6480464 bis(4-hydroxyphenyl)sulfone results in increased expression of TET2 mRNA CTD PMID:31601247 4,4'-sulfonyldiphenol decreases expression ISO RGD:1606790 6480464 bis(4-hydroxyphenyl)sulfone results in decreased expression of TET2 mRNA, bis(4-hydroxyphenyl)sulfone results in decreased expression of TET2 protein CTD PMID:32105160 4,4'-sulfonyldiphenol increases methylation ISO RGD:1606790 6480464 bis(4-hydroxyphenyl)sulfone results in increased methylation of TET2 promoter CTD PMID:32105160 5-(hydroxymethyl)cytosine multiple interactions ISO RGD:1323180 6480464 TET2 protein affects the reaction [2 more ... CTD PMID:24214992 5-(hydroxymethyl)cytosine multiple interactions ISO RGD:1606790 6480464 bis(4-hydroxyphenyl)sulfone promotes the reaction [TET2 protein results in increased abundance of 5-hydroxymethylcytosine] more ... CTD PMID:32105160 5-(hydroxymethyl)cytosine increases abundance ISO RGD:1606790 6480464 TET2 protein results in increased abundance of 5-hydroxymethylcytosine CTD PMID:32105160 5-methylcytosine multiple interactions ISO RGD:1323180 6480464 TET2 protein affects the reaction [2 more ... CTD PMID:24214992 acrylamide decreases expression EXP 6480464 Acrylamide results in decreased expression of TET2 mRNA CTD PMID:28959563 acrylamide decreases expression ISO RGD:1323180 6480464 Acrylamide results in decreased expression of TET2 mRNA CTD PMID:30807115 aflatoxin B1 decreases methylation ISO RGD:1606790 6480464 Aflatoxin B1 results in decreased methylation of TET2 gene CTD PMID:27153756 aldrin increases response to substance ISO RGD:1606790 6480464 TET2 gene SNP results in increased susceptibility to Aldrin CTD PMID:23593118 all-trans-retinoic acid increases expression ISO RGD:1606790 6480464 Tretinoin results in increased expression of TET2 mRNA CTD PMID:33167477 aristolochic acid A decreases expression ISO RGD:1606790 6480464 aristolochic acid I results in decreased expression of TET2 mRNA CTD PMID:33212167 arsane affects methylation ISO RGD:1606790 6480464 Arsenic affects the methylation of TET2 gene CTD PMID:25304211 arsenic atom affects methylation ISO RGD:1606790 6480464 Arsenic affects the methylation of TET2 gene CTD PMID:25304211 arsenite(3-) multiple interactions ISO RGD:1606790 6480464 arsenite inhibits the reaction [G3BP1 protein binds to TET2 mRNA] CTD PMID:32406909 arsenous acid decreases expression EXP 6480464 Arsenic Trioxide results in decreased expression of TET2 mRNA CTD PMID:29223816 benzo[a]pyrene increases expression ISO RGD:1606790 6480464 Benzo(a)pyrene results in increased expression of TET2 mRNA CTD PMID:27901495 benzo[a]pyrene increases methylation ISO RGD:1606790 6480464 Benzo(a)pyrene results in increased methylation of TET2 5' UTR CTD PMID:27901495 benzo[a]pyrene decreases methylation ISO RGD:1606790 6480464 Benzo(a)pyrene results in decreased methylation of TET2 promoter CTD PMID:27901495 bis(2-ethylhexyl) phthalate decreases expression ISO RGD:1323180 6480464 Diethylhexyl Phthalate results in decreased expression of TET2 mRNA CTD PMID:31211961 bis(2-ethylhexyl) phthalate affects expression ISO RGD:1323180 6480464 Diethylhexyl Phthalate affects the expression of TET2 mRNA CTD PMID:32628958 bisphenol A affects expression EXP 6480464 bisphenol A affects the expression of TET2 mRNA CTD PMID:25181051 bisphenol A increases expression ISO RGD:1323180 6480464 bisphenol A results in increased expression of TET2 mRNA CTD PMID:31649729 , PMID:35598803 bisphenol A increases expression ISO RGD:1606790 6480464 bisphenol A results in increased expression of TET2 mRNA CTD PMID:31601247 bisphenol A decreases expression ISO RGD:1323180 6480464 bisphenol A results in decreased expression of TET2 mRNA CTD PMID:33221593 bisphenol A multiple interactions ISO RGD:1606790 6480464 [bisphenol A promotes the reaction [WDR5 protein binds to TET2 protein]] which binds to ESR2 exon more ... CTD PMID:32105160 , PMID:33022573 bisphenol A increases methylation ISO RGD:1606790 6480464 bisphenol A results in increased methylation of TET2 promoter CTD PMID:32105160 bisphenol A decreases expression ISO RGD:1606790 6480464 bisphenol A results in decreased expression of TET2 mRNA, bisphenol A results in decreased expression of TET2 protein CTD PMID:32105160 butanal decreases expression ISO RGD:1606790 6480464 butyraldehyde results in decreased expression of TET2 mRNA CTD PMID:26079696 cadmium atom multiple interactions ISO RGD:1606790 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of TET2 mRNA CTD PMID:35301059 cadmium dichloride multiple interactions ISO RGD:1606790 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of TET2 mRNA CTD PMID:35301059 caffeine decreases phosphorylation ISO RGD:1606790 6480464 Caffeine results in decreased phosphorylation of TET2 protein CTD PMID:35688186 carbon nanotube decreases expression ISO RGD:1323180 6480464 Nanotubes more ... CTD PMID:25554681 chloroquine multiple interactions ISO RGD:1606790 6480464 Chloroquine inhibits the reaction [dorsomorphin results in decreased expression of TET2 mRNA], Chloroquine inhibits the reaction [dorsomorphin results in decreased expression of TET2 protein] CTD PMID:31900833 choline multiple interactions ISO RGD:1323180 6480464 [Methionine deficiency co-treated with Choline deficiency] results in increased expression of TET2 mRNA CTD PMID:25690533 chromium(6+) decreases expression ISO RGD:1606790 6480464 chromium hexavalent ion results in decreased expression of TET2 mRNA CTD PMID:30690063 cisplatin multiple interactions ISO RGD:1606790 6480464 [Cisplatin co-treated with jinfukang] results in decreased expression of TET2 mRNA CTD PMID:27392435 curcumin increases expression ISO RGD:1606790 150429654 curcumin increases expression of TET2 mRNA and protein in stomach RGD desferrioxamine B decreases expression ISO RGD:1606790 6480464 Deferoxamine results in decreased expression of TET2 protein CTD PMID:23483119 diarsenic trioxide decreases expression EXP 6480464 Arsenic Trioxide results in decreased expression of TET2 mRNA CTD PMID:29223816 dibenz[a,h]anthracene increases expression ISO RGD:1323180 6480464 1 more ... CTD PMID:26377693 dorsomorphin decreases expression ISO RGD:1606790 6480464 dorsomorphin results in decreased expression of TET2 mRNA, dorsomorphin results in decreased expression of TET2 protein CTD PMID:31900833 dorsomorphin multiple interactions ISO RGD:1606790 6480464 [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 , PMID:31900833 doxorubicin increases expression ISO RGD:1323180 6480464 Doxorubicin results in increased expression of TET2 mRNA CTD PMID:25896364 doxorubicin decreases expression ISO RGD:1606790 6480464 Doxorubicin results in decreased expression of TET2 mRNA CTD PMID:29803840 entinostat decreases expression ISO RGD:1606790 6480464 entinostat results in decreased expression of TET2 mRNA CTD PMID:27188386 folic acid decreases expression ISO RGD:1323180 6480464 Folic Acid results in decreased expression of TET2 mRNA CTD PMID:25629700 formaldehyde decreases expression ISO RGD:1606790 6480464 Formaldehyde results in decreased expression of TET2 mRNA CTD PMID:20655997 geldanamycin increases expression ISO RGD:1606790 6480464 geldanamycin results in increased expression of TET2 mRNA CTD PMID:26705709 L-ascorbic acid multiple interactions ISO RGD:1606790 6480464 Ascorbic Acid inhibits the reaction [sodium arsenite results in decreased expression of TET2 protein] CTD PMID:33388378 L-methionine multiple interactions ISO RGD:1323180 6480464 [Methionine deficiency co-treated with Choline deficiency] results in increased expression of TET2 mRNA CTD PMID:25690533 leflunomide increases expression ISO RGD:1606790 6480464 leflunomide results in increased expression of TET2 mRNA CTD PMID:28988120 lipopolysaccharide increases expression ISO RGD:1606790 6480464 Lipopolysaccharides results in increased expression of TET2 protein CTD PMID:29567563 lipopolysaccharide multiple interactions ISO RGD:1606790 6480464 apigenin-6, 8-di-C-glycopyranoside promotes the reaction [Lipopolysaccharides results in increased expression of TET2 protein] CTD PMID:29567563 methylmercury chloride decreases expression ISO RGD:1606790 6480464 methylmercuric chloride results in decreased expression of TET2 mRNA CTD PMID:28001369 morphine affects expression ISO RGD:1323180 6480464 Morphine affects the expression of TET2 mRNA CTD PMID:33891991 N-acetyl-L-cysteine multiple interactions ISO RGD:1606790 6480464 Acetylcysteine inhibits the reaction [dorsomorphin results in decreased expression of TET2 protein] CTD PMID:31900833 nickel atom multiple interactions ISO RGD:1606790 6480464 [nickel chloride results in increased abundance of Nickel] which results in increased expression of TET2 mRNA CTD PMID:34571076 nickel dichloride multiple interactions ISO RGD:1606790 6480464 [nickel chloride results in increased abundance of Nickel] which results in increased expression of TET2 mRNA CTD PMID:34571076 p-chloromercuribenzoic acid increases expression ISO RGD:1606790 6480464 p-Chloromercuribenzoic Acid results in increased expression of TET2 mRNA CTD PMID:27188386 pentanal decreases expression ISO RGD:1606790 6480464 pentanal results in decreased expression of TET2 mRNA CTD PMID:26079696 perfluorooctane-1-sulfonic acid decreases expression ISO RGD:1606790 6480464 perfluorooctane sulfonic acid results in decreased expression of TET2 mRNA CTD PMID:27153767 perfluorooctanoic acid affects expression ISO RGD:1606790 6480464 perfluorooctanoic acid affects the expression of TET2 mRNA CTD PMID:32068100 permethrin increases expression EXP 6480464 Permethrin results in increased expression of TET2 mRNA CTD PMID:31175960 potassium chromate multiple interactions ISO RGD:1606790 6480464 [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of TET2 mRNA CTD PMID:22079256 potassium chromate decreases expression ISO RGD:1606790 6480464 potassium chromate(VI) results in decreased expression of TET2 mRNA CTD PMID:22079256 , PMID:22714537 propanal decreases expression ISO RGD:1606790 6480464 propionaldehyde results in decreased expression of TET2 mRNA CTD PMID:26079696 SB 431542 multiple interactions ISO RGD:1606790 6480464 [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of TET2 mRNA CTD PMID:27188386 sodium arsenate increases expression ISO RGD:1323180 6480464 sodium arsenate results in increased expression of TET2 mRNA CTD PMID:21795629 sodium arsenite decreases expression ISO RGD:1606790 6480464 sodium arsenite results in decreased expression of TET2 protein CTD PMID:33388378 sodium arsenite increases expression ISO RGD:1606790 6480464 sodium arsenite results in increased expression of TET2 mRNA CTD PMID:29175454 sodium arsenite multiple interactions ISO RGD:1606790 6480464 Ascorbic Acid inhibits the reaction [sodium arsenite results in decreased expression of TET2 protein] more ... CTD PMID:29175454 , PMID:33388378 sodium fluoride decreases expression ISO RGD:1323180 6480464 Sodium Fluoride results in decreased expression of TET2 mRNA CTD PMID:27862939 succimer multiple interactions ISO RGD:1323180 6480464 [Succimer binds to Magnetite Nanoparticles] which results in decreased expression of TET2 mRNA, [Succimer co-treated with Magnetite Nanoparticles] affects the expression of TET2 mRNA CTD PMID:21641980 , PMID:26378955 tetrachloro-1,4-benzoquinone multiple interactions ISO RGD:1323180 6480464 TET2 protein affects the reaction [Chloranil results in increased chemical synthesis of 5-hydroxymethylcytosine], TET2 protein affects the reaction [Chloranil results in increased oxidation of 5-Methylcytosine] CTD PMID:24214992 tetrachlorohydroquinone multiple interactions ISO RGD:1323180 6480464 TET2 protein affects the reaction [2 more ... CTD PMID:24214992 thimerosal decreases expression ISO RGD:1606790 6480464 Thimerosal results in decreased expression of TET2 mRNA CTD PMID:27188386 thioacetamide increases expression EXP 6480464 Thioacetamide results in increased expression of TET2 mRNA CTD PMID:34492290 trichloroethene decreases expression ISO RGD:1323180 150429687 trichloroethene decreases expression of Tet2 mRNA in liver RGD trichloroethene decreases expression EXP 6480464 Trichloroethylene results in decreased expression of TET2 mRNA CTD PMID:27618143 trichloroethene decreases expression ISO RGD:1323180 6480464 Trichloroethylene results in decreased expression of TET2 mRNA CTD PMID:25549359 , PMID:27618143 trichostatin A decreases expression ISO RGD:1606790 6480464 trichostatin A results in decreased expression of TET2 mRNA CTD PMID:24935251 , PMID:26272509 trichostatin A multiple interactions ISO RGD:1606790 6480464 [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of TET2 mRNA CTD PMID:27188386 triptonide decreases expression ISO RGD:1323180 6480464 triptonide results in decreased expression of TET2 mRNA CTD PMID:33045310 uranium atom decreases expression EXP 6480464 Uranium results in decreased expression of TET2 mRNA CTD PMID:29024790 urethane increases expression ISO RGD:1606790 6480464 Urethane results in increased expression of TET2 mRNA CTD PMID:28818685 valproic acid affects expression ISO RGD:1606790 6480464 Valproic Acid affects the expression of TET2 mRNA CTD PMID:25979313 valproic acid affects splicing EXP 6480464 Valproic Acid affects the splicing of TET2 mRNA CTD PMID:29427782 valproic acid decreases expression ISO RGD:1606790 6480464 Valproic Acid results in decreased expression of TET2 mRNA CTD PMID:23179753 more ... vinclozolin increases expression EXP 6480464 vinclozolin results in increased expression of TET2 mRNA CTD PMID:23034163 vorinostat decreases expression ISO RGD:1606790 6480464 vorinostat results in decreased expression of TET2 mRNA CTD PMID:27188386