Sec63 (SEC63 homolog, protein translocation regulator) - Rat Genome Database

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Gene: Sec63 (SEC63 homolog, protein translocation regulator) Rattus norvegicus
Analyze
Symbol: Sec63
Name: SEC63 homolog, protein translocation regulator
RGD ID: 1304984
Description: Predicted to enable protein transmembrane transporter activity. Predicted to be involved in SRP-dependent cotranslational protein targeting to membrane and post-translational protein targeting to membrane, translocation. Predicted to act upstream of or within liver development; multicellular organism aging; and nitrogen compound metabolic process. Predicted to be located in endoplasmic reticulum and membrane. Predicted to be part of Sec62/Sec63 complex. Human ortholog(s) of this gene implicated in polycystic liver disease. Orthologous to human SEC63 (SEC63 homolog, protein translocation regulator); PARTICIPATES IN Endoplasmic Reticulum-associated degradation pathway; INTERACTS WITH 2,4-dinitrotoluene; 2,6-dinitrotoluene; acrylamide.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC309858; SEC63 homolog; SEC63 homolog (S. cerevisiae); SEC63-like; SEC63-like (S. cerevisiae) ; SEC63-like protein; translocation protein SEC63 homolog
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.22046,245,101 - 46,314,055 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2046,245,101 - 46,314,055 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2047,962,490 - 48,031,437 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.02047,612,670 - 47,681,616 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.02048,300,146 - 48,368,853 (+)NCBIRnor_WKY
Rnor_6.02047,494,270 - 47,563,222 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2047,494,270 - 47,563,222 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02049,156,193 - 49,225,366 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42046,669,125 - 46,738,077 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12046,693,553 - 46,762,289 (+)NCBI
Celera2053,663,315 - 53,732,035 (-)NCBICelera
Cytogenetic Map20q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Mutations in SEC63 cause autosomal dominant polycystic liver disease. Davila S, etal., Nat Genet. 2004 Jun;36(6):575-7. doi: 10.1038/ng1357. Epub 2004 May 9.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
6. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:21685914   PMID:22375059   PMID:22658674   PMID:29719251  


Genomics

Comparative Map Data
Sec63
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.22046,245,101 - 46,314,055 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2046,245,101 - 46,314,055 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2047,962,490 - 48,031,437 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.02047,612,670 - 47,681,616 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.02048,300,146 - 48,368,853 (+)NCBIRnor_WKY
Rnor_6.02047,494,270 - 47,563,222 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2047,494,270 - 47,563,222 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02049,156,193 - 49,225,366 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42046,669,125 - 46,738,077 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12046,693,553 - 46,762,289 (+)NCBI
Celera2053,663,315 - 53,732,035 (-)NCBICelera
Cytogenetic Map20q13NCBI
SEC63
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh386107,867,756 - 107,958,208 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl6107,867,756 - 107,958,208 (-)EnsemblGRCh38hg38GRCh38
GRCh376108,188,960 - 108,279,412 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 366108,298,215 - 108,386,086 (-)NCBINCBI36Build 36hg18NCBI36
Build 346108,298,214 - 108,386,086NCBI
Celera6108,935,760 - 109,025,964 (-)NCBICelera
Cytogenetic Map6q21NCBI
HuRef6105,758,265 - 105,848,248 (-)NCBIHuRef
CHM1_16108,451,504 - 108,542,131 (-)NCBICHM1_1
T2T-CHM13v2.06109,045,456 - 109,135,362 (-)NCBIT2T-CHM13v2.0
Sec63
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391042,637,492 - 42,708,510 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1042,637,492 - 42,708,510 (+)EnsemblGRCm39 Ensembl
GRCm381042,761,496 - 42,832,514 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1042,761,496 - 42,832,514 (+)EnsemblGRCm38mm10GRCm38
MGSCv371042,481,302 - 42,552,320 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361042,450,141 - 42,517,702 (+)NCBIMGSCv36mm8
Celera1043,628,635 - 43,699,289 (+)NCBICelera
Cytogenetic Map10B2NCBI
cM Map1022.89NCBI
Sec63
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541133,063,989 - 33,126,105 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541133,063,056 - 33,126,325 (-)NCBIChiLan1.0ChiLan1.0
SEC63
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.16109,536,790 - 109,620,748 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl6109,538,184 - 109,595,518 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v06105,673,265 - 105,757,422 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
SEC63
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11264,983,442 - 65,028,573 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1264,770,434 - 64,844,883 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01265,829,612 - 65,904,228 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1265,830,569 - 65,904,193 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11265,185,870 - 65,260,323 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01265,031,615 - 65,106,070 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01265,305,260 - 65,379,711 (-)NCBIUU_Cfam_GSD_1.0
Sec63
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494699,904,722 - 99,947,041 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365644,179,584 - 4,221,904 (-)EnsemblSpeTri2.0
SpeTri2.0NW_0049365644,182,330 - 4,221,927 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SEC63
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl174,000,688 - 74,078,582 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1174,003,428 - 74,078,605 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2183,274,127 - 83,349,307 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SEC63
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11365,902,796 - 65,993,092 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1365,902,956 - 65,996,514 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604038,236,474 - 38,324,301 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Sec63
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462478014,322,707 - 14,405,673 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462478014,322,651 - 14,405,674 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Sec63
312 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:463
Count of miRNA genes:251
Interacting mature miRNAs:331
Transcripts:ENSRNOT00000036365
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2305926Iddm37Insulin dependent diabetes mellitus QTL 376blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)20152784246527842Rat
1641915Colcr9Colorectal carcinoma resistance QTL 92.970.0024intestine integrity trait (VT:0010554)benign colorectal tumor number (CMO:0001795)20153065546530655Rat
1598816Memor12Memory QTL 122.4exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)20260683647606836Rat
7411652Foco24Food consumption QTL 240.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)201175751554435887Rat
9590092Insglur9Insulin/glucose ratio QTL 918.380.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)201175751554435887Rat
4889610Pancm3Pancreatic morphology QTL 33.750.001pancreas mass (VT:0010144)pancreas wet weight (CMO:0000626)201761783247606836Rat
2317880Alcrsp25Alcohol response QTL 252.3response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)201769755054435887Rat
2303626Vencon10Ventilatory control QTL 100.001respiration trait (VT:0001943)respiration rate (CMO:0000289)201919072154435887Rat
2303578Gluco50Glucose level QTL 502blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)202510672254435887Rat
2303587Bw93Body weight QTL 9313body mass (VT:0001259)body weight (CMO:0000012)202510672254435887Rat
2300188Bmd68Bone mineral density QTL 686.40.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)202510672254435887Rat
1331747Hrtrt16Heart rate QTL 163.163heart pumping trait (VT:2000009)heart rate (CMO:0000002)202520973454435887Rat
1598869Memor6Memory QTL 63.1exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)202924438854435887Rat

Markers in Region
D20Rat16  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22046,266,352 - 46,266,514 (+)MAPPERmRatBN7.2
Rnor_6.02047,515,521 - 47,515,682NCBIRnor6.0
Rnor_5.02049,177,445 - 49,177,606UniSTSRnor5.0
RGSC_v3.42046,690,375 - 46,690,537RGDRGSC3.4
RGSC_v3.42046,690,376 - 46,690,537UniSTSRGSC3.4
RGSC_v3.12046,714,579 - 46,714,741RGD
Celera2053,710,623 - 53,710,784UniSTS
RH 2.0 Map20568.0RGD
FHH x ACI Map2031.8299RGD
Cytogenetic Map20q13UniSTS
BE105041  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22046,310,669 - 46,310,827 (+)MAPPERmRatBN7.2
Rnor_6.02047,559,837 - 47,559,994NCBIRnor6.0
Rnor_5.02049,221,981 - 49,222,138UniSTSRnor5.0
RGSC_v3.42046,734,692 - 46,734,849UniSTSRGSC3.4
Celera2053,666,543 - 53,666,700UniSTS
RH 3.4 Map20490.83UniSTS
Cytogenetic Map20q13UniSTS
RH134694  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22046,313,665 - 46,313,854 (+)MAPPERmRatBN7.2
Rnor_6.02047,562,833 - 47,563,021NCBIRnor6.0
Rnor_5.02049,224,977 - 49,225,165UniSTSRnor5.0
RGSC_v3.42046,737,688 - 46,737,876UniSTSRGSC3.4
Celera2053,663,516 - 53,663,704UniSTS
RH 3.4 Map20490.84UniSTS
Cytogenetic Map20q13UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 34 57 41 19 41 1 2 74 35 41 11 1
Low 9 7 9 7
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000036365   ⟹   ENSRNOP00000035059
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2046,245,101 - 46,314,055 (+)Ensembl
Rnor_6.0 Ensembl2047,494,270 - 47,563,222 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000087718   ⟹   ENSRNOP00000069126
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2046,245,235 - 46,311,528 (+)Ensembl
Rnor_6.0 Ensembl2047,494,424 - 47,559,979 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000110304   ⟹   ENSRNOP00000085126
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2046,245,331 - 46,314,055 (+)Ensembl
RefSeq Acc Id: NM_001107637   ⟹   NP_001101107
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.22046,245,101 - 46,314,055 (+)NCBI
Rnor_6.02047,494,270 - 47,563,222 (+)NCBI
Rnor_5.02049,156,193 - 49,225,366 (+)NCBI
RGSC_v3.42046,669,125 - 46,738,077 (+)RGD
Celera2053,663,315 - 53,732,035 (-)RGD
Sequence:
RefSeq Acc Id: XM_006256570   ⟹   XP_006256632
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.22046,245,186 - 46,314,053 (+)NCBI
Rnor_6.02047,494,380 - 47,563,220 (+)NCBI
Rnor_5.02049,156,193 - 49,225,366 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006256571   ⟹   XP_006256633
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.22046,245,185 - 46,310,614 (+)NCBI
Rnor_6.02047,494,379 - 47,563,220 (+)NCBI
Rnor_5.02049,156,193 - 49,225,366 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001101107 (Get FASTA)   NCBI Sequence Viewer  
  XP_006256632 (Get FASTA)   NCBI Sequence Viewer  
  XP_006256633 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL99699 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_001101107   ⟸   NM_001107637
- UniProtKB: D4A2Z6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006256632   ⟸   XM_006256570
- Peptide Label: isoform X1
- UniProtKB: A0A0G2JUJ9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006256633   ⟸   XM_006256571
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSRNOP00000069126   ⟸   ENSRNOT00000087718
RefSeq Acc Id: ENSRNOP00000035059   ⟸   ENSRNOT00000036365
RefSeq Acc Id: ENSRNOP00000085126   ⟸   ENSRNOT00000110304
Protein Domains
J

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2JUJ9-F1-model_v2 AlphaFold A0A0G2JUJ9 1-760 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13701674
Promoter ID:EPDNEW_R12195
Type:initiation region
Name:Sec63_1
Description:SEC63 homolog, protein translocation regulator
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.02047,494,382 - 47,494,442EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1304984 AgrOrtholog
BioCyc Gene G2FUF-3355 BioCyc
Ensembl Genes ENSRNOG00000000314 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000035059 ENTREZGENE
  ENSRNOP00000035059.4 UniProtKB/TrEMBL
  ENSRNOP00000069126 ENTREZGENE
  ENSRNOP00000069126.1 UniProtKB/TrEMBL
  ENSRNOP00000085126.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000036365 ENTREZGENE
  ENSRNOT00000036365.6 UniProtKB/TrEMBL
  ENSRNOT00000087718 ENTREZGENE
  ENSRNOT00000087718.2 UniProtKB/TrEMBL
  ENSRNOT00000110304.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.287.110 UniProtKB/TrEMBL
  2.60.40.150 UniProtKB/TrEMBL
InterPro C2_domain_sf UniProtKB/TrEMBL
  DnaJ_dom_sf UniProtKB/TrEMBL
  DnaJ_N UniProtKB/TrEMBL
  Ig_E-set UniProtKB/TrEMBL
  Sec63 UniProtKB/TrEMBL
  Sec63-dom UniProtKB/TrEMBL
KEGG Report rno:309858 UniProtKB/TrEMBL
NCBI Gene 309858 ENTREZGENE
PANTHER PTHR24075:SF0 UniProtKB/TrEMBL
Pfam DnaJ UniProtKB/TrEMBL
  Sec63 UniProtKB/TrEMBL
PhenoGen Sec63 PhenoGen
PRINTS DNAJPROTEIN UniProtKB/TrEMBL
PROSITE DNAJ_2 UniProtKB/TrEMBL
SMART DnaJ UniProtKB/TrEMBL
  Sec63 UniProtKB/TrEMBL
Superfamily-SCOP DnaJ_N UniProtKB/TrEMBL
  SSF81296 UniProtKB/TrEMBL
UniProt A0A0G2JUJ9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZYJ9_RAT UniProtKB/TrEMBL
  D4A2Z6 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-08-11 Sec63  SEC63 homolog, protein translocation regulator  Sec63  SEC63 homolog (S. cerevisiae)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-11-20 Sec63  SEC63 homolog (S. cerevisiae)  Sec63  SEC63-like (S. cerevisiae)   Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Sec63  SEC63-like (S. cerevisiae)   Sec63_predicted  SEC63-like (S. cerevisiae) (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Sec63_predicted  SEC63-like (S. cerevisiae) (predicted)      Symbol and Name status set to approved 70820 APPROVED