Kyat3 (kynurenine aminotransferase 3) - Rat Genome Database

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Gene: Kyat3 (kynurenine aminotransferase 3) Rattus norvegicus
Analyze
Symbol: Kyat3
Name: kynurenine aminotransferase 3
RGD ID: 1359262
Description: Predicted to enable kynurenine-glyoxylate transaminase activity; kynurenine-oxoglutarate transaminase activity; and protein homodimerization activity. Predicted to be involved in 2-oxoglutarate metabolic process and kynurenine metabolic process. Predicted to be active in mitochondrion. Orthologous to human KYAT3 (kynurenine aminotransferase 3); PARTICIPATES IN kynurenine metabolic pathway; selenoamino acid metabolic pathway; tryptophan metabolic pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-diaminodiphenylmethane.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: Ccbl2; cysteine conjugate-beta lyase 2; cysteine-S-conjugate beta-lyase 2; Kat3; KATIII; kynurenine aminotransferase III; kynurenine aminotransferase III-like; kynurenine--glyoxylate transaminase; kynurenine--oxoglutarate transaminase 3; kynurenine--oxoglutarate transaminase III; LOC100361841
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.22231,701,881 - 231,747,462 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl2231,701,963 - 231,747,227 (+)Ensembl
Rnor_6.02248,644,473 - 248,690,289 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2248,649,441 - 248,690,089 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02267,169,695 - 267,220,549 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42240,849,349 - 240,857,337 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12240,829,675 - 240,844,071 (+)NCBI
Celera2223,713,699 - 223,757,924 (+)NCBICelera
Cytogenetic Map2q44NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Structure, expression, and function of kynurenine aminotransferases in human and rodent brains. Han Q, etal., Cell Mol Life Sci. 2010 Feb;67(3):353-68. doi: 10.1007/s00018-009-0166-4. Epub 2009 Oct 15.
3. The kynurenine pathway and neurodegenerative disease. Maddison DC and Giorgini F, Semin Cell Dev Biol. 2015 Apr;40:134-41. doi: 10.1016/j.semcdb.2015.03.002. Epub 2015 Mar 12.
4. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
5. GOA pipeline RGD automated data pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. Comprehensive gene review and curation RGD comprehensive gene curation
Additional References at PubMed
PMID:16376499   PMID:18614015   PMID:19029248   PMID:22681889  


Genomics

Comparative Map Data
Kyat3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.22231,701,881 - 231,747,462 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl2231,701,963 - 231,747,227 (+)Ensembl
Rnor_6.02248,644,473 - 248,690,289 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2248,649,441 - 248,690,089 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02267,169,695 - 267,220,549 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42240,849,349 - 240,857,337 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12240,829,675 - 240,844,071 (+)NCBI
Celera2223,713,699 - 223,757,924 (+)NCBICelera
Cytogenetic Map2q44NCBI
KYAT3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38188,921,044 - 88,992,960 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl188,935,773 - 88,992,953 (-)EnsemblGRCh38hg38GRCh38
GRCh37189,386,727 - 89,458,643 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36189,174,044 - 89,231,104 (-)NCBINCBI36hg18NCBI36
Celera187,647,258 - 87,704,434 (-)NCBI
Cytogenetic Map1p22.2NCBI
HuRef187,518,867 - 87,576,019 (-)NCBIHuRef
CHM1_1189,516,514 - 89,573,685 (-)NCBICHM1_1
T2T-CHM13v2.0188,764,436 - 88,836,357 (-)NCBI
Kyat3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm393142,406,780 - 142,450,672 (+)NCBIGRCm39mm39
GRCm39 Ensembl3142,406,812 - 142,452,631 (+)Ensembl
GRCm383142,701,019 - 142,744,911 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl3142,701,051 - 142,746,870 (+)EnsemblGRCm38mm10GRCm38
MGSCv373142,364,044 - 142,407,874 (+)NCBIGRCm37mm9NCBIm37
MGSCv363142,638,466 - 142,682,296 (+)NCBImm8
Celera3149,133,370 - 149,177,239 (+)NCBICelera
Cytogenetic Map3H1NCBI
Kyat3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554235,344,562 - 5,391,518 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554235,340,863 - 5,388,460 (+)NCBIChiLan1.0ChiLan1.0
KYAT3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1190,403,072 - 90,460,426 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl190,403,072 - 90,460,426 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0191,636,681 - 91,708,859 (-)NCBIMhudiblu_PPA_v0panPan3
KYAT3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1659,409,715 - 59,473,238 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl659,416,191 - 59,473,232 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha662,118,320 - 62,181,537 (+)NCBI
ROS_Cfam_1.0659,920,984 - 59,984,529 (+)NCBI
ROS_Cfam_1.0 Ensembl659,921,026 - 59,984,531 (+)Ensembl
UMICH_Zoey_3.1659,486,769 - 59,550,195 (+)NCBI
UNSW_CanFamBas_1.0659,441,849 - 59,505,435 (+)NCBI
UU_Cfam_GSD_1.0659,927,659 - 59,991,112 (+)NCBI
Kyat3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505899,313,496 - 99,361,813 (-)NCBI
SpeTri2.0NW_00493673277,427 - 125,816 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KYAT3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl4127,451,516 - 127,507,760 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.14127,451,475 - 127,507,766 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24139,676,619 - 139,732,902 (+)NCBISscrofa10.2Sscrofa10.2susScr3
KYAT3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12044,416,179 - 44,488,388 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl2044,419,712 - 44,488,491 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366603373,428,283 - 73,491,315 (-)NCBIVero_WHO_p1.0
Kyat3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247428,599,862 - 8,659,110 (+)NCBIHetGla_female_1.0hetGla2

Position Markers
D2Rat151  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22231,745,742 - 231,745,867 (+)MAPPERmRatBN7.2
Rnor_6.02248,688,805 - 248,688,929NCBIRnor6.0
Rnor_5.02267,219,065 - 267,219,189UniSTSRnor5.0
RGSC_v3.42240,855,846 - 240,855,971RGDRGSC3.4
RGSC_v3.42240,855,847 - 240,855,971UniSTSRGSC3.4
RGSC_v3.12240,842,586 - 240,842,711RGD
Celera2223,756,440 - 223,756,564UniSTS
FHH x ACI Map2112.8599RGD
FHH x ACI Map2112.8599UniSTS
Cytogenetic Map2q44UniSTS
RH140542  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22231,747,212 - 231,747,385 (+)MAPPERmRatBN7.2
Rnor_6.02248,690,275 - 248,690,447NCBIRnor6.0
Rnor_5.02267,220,535 - 267,220,707UniSTSRnor5.0
RGSC_v3.42240,857,317 - 240,857,489UniSTSRGSC3.4
Celera2223,757,910 - 223,758,082UniSTS
RH 3.4 Map21580.0UniSTS
Cytogenetic Map2q44UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
724534Uae6Urinary albumin excretion QTL 610urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)278665619249053267Rat
1641891Alcrsp17Alcohol response QTL 17response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)2149559561249053267Rat
61366Iddm3Insulin dependent diabetes mellitus QTL 34.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)2189599258234599258Rat
61398Bp50Blood pressure QTL 504.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2189599258234599258Rat
2317752Glom23Glomerulus QTL 233.6urine protein amount (VT:0005160)urine protein level (CMO:0000591)2193452645245889826Rat
1598813Memor9Memory QTL 92.7exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)2199341726234244620Rat
1598835Anxrr18Anxiety related response QTL 182.98body movement coordination trait (VT:0005424)number of rearing movements in an experimental apparatus (CMO:0001752)2200990457245990457Rat
2298479Eau5Experimental allergic uveoretinitis QTL 50.0021uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)2202446871237938339Rat
7207490Bss111Bone structure and strength QTL 1116.4femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)2211744537249053267Rat
7207482Bss107Bone structure and strength QTL 1077femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)2211744537249053267Rat
7207484Bss108Bone structure and strength QTL 1085.3femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)2211744537249053267Rat
1298075Scl17Serum cholesterol level QTL 173.4blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)2211744537249053267Rat
1549836Bss2Bone structure and strength QTL 27.5femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)2211744537249053267Rat
2317885Alcrsp28Alcohol response QTL 282.10.63response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)2212828222249053267Rat
1300126Bp175Blood pressure QTL 1753.46arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2214226044247136170Rat
2313073Bmd75Bone mineral density QTL 754.10.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)2215377404237938339Rat
1331767Hrtrt12Heart rate QTL 123.373heart pumping trait (VT:2000009)heart rate (CMO:0000002)2218414747240841241Rat
2293833Kiddil8Kidney dilation QTL 82.9kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)2219753301247136170Rat
2293844Kiddil7Kidney dilation QTL 73.5kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)2219753301247136170Rat
9587428Epfw6Epididymal fat weight QTL 67.470.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)2223389739249053267Rat
7411555Bw132Body weight QTL 1320.001body mass (VT:0001259)body weight gain (CMO:0000420)2223389739249053267Rat
631563Hcuc3Hepatic copper content QTL 33.87hepatic copper amount (VT:0003065)liver copper weight to liver dry weight ratio (CMO:0001512)2229059610249053267Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:41
Count of miRNA genes:39
Interacting mature miRNAs:40
Transcripts:ENSRNOT00000067165
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 2 15 44 39 1 39 60 35 33
Low 1 28 13 2 18 2 8 11 14 8 11 8
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000067165   ⟹   ENSRNOP00000059667
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2231,701,963 - 231,747,227 (+)Ensembl
Rnor_6.0 Ensembl2248,649,441 - 248,690,089 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000101068   ⟹   ENSRNOP00000083094
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2231,701,963 - 231,747,227 (+)Ensembl
RefSeq Acc Id: NM_001015037   ⟹   NP_001015037
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.22231,701,934 - 231,747,227 (+)NCBI
Rnor_6.02248,644,473 - 248,690,289 (+)NCBI
Rnor_5.02267,169,695 - 267,220,549 (+)NCBI
Celera2223,713,699 - 223,757,924 (+)RGD
Sequence:
RefSeq Acc Id: XM_039102971   ⟹   XP_038958899
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.22231,702,018 - 231,747,462 (+)NCBI
RefSeq Acc Id: XM_039102972   ⟹   XP_038958900
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.22231,701,881 - 231,747,462 (+)NCBI
RefSeq Acc Id: XM_039102974   ⟹   XP_038958902
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.22231,706,477 - 231,747,462 (+)NCBI
RefSeq Acc Id: XM_039102975   ⟹   XP_038958903
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.22231,706,477 - 231,747,462 (+)NCBI
RefSeq Acc Id: XM_039102976   ⟹   XP_038958904
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.22231,718,932 - 231,747,462 (+)NCBI
RefSeq Acc Id: XM_039102977   ⟹   XP_038958905
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.22231,701,905 - 231,747,462 (+)NCBI
Reference Sequences
RefSeq Acc Id: NP_001015037   ⟸   NM_001015037
- UniProtKB: Q58FK9 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSRNOP00000059667   ⟸   ENSRNOT00000067165
RefSeq Acc Id: XP_038958900   ⟸   XM_039102972
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038958905   ⟸   XM_039102977
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038958899   ⟸   XM_039102971
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038958902   ⟸   XM_039102974
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038958903   ⟸   XM_039102975
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038958904   ⟸   XM_039102976
- Peptide Label: isoform X3
RefSeq Acc Id: ENSRNOP00000083094   ⟸   ENSRNOT00000101068

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q58FK9-F1-model_v2 AlphaFold Q58FK9 1-454 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Strain Variation

Strain Sequence Variants (MRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1359262 AgrOrtholog
BioCyc Gene G2FUF-50985 BioCyc
Ensembl Genes ENSRNOG00000043426 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000059667.4 UniProtKB/TrEMBL
  ENSRNOP00000083094 ENTREZGENE
  ENSRNOP00000083094.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000067165.4 UniProtKB/TrEMBL
  ENSRNOT00000101068 ENTREZGENE
  ENSRNOT00000101068.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.640.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.90.1150.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Aminotransferase_I/II UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  KAT_III UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PyrdxlP-dep_Trfase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PyrdxlP-dep_Trfase_dom1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PyrdxlP-dep_Trfase_major UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:541589 UniProtKB/Swiss-Prot
NCBI Gene 541589 ENTREZGENE
PANTHER PTHR43807:SF6 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Aminotran_1_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Kyat3 PhenoGen
Superfamily-SCOP SSF53383 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I5ZUT0_RAT UniProtKB/TrEMBL
  F1M572_RAT UniProtKB/TrEMBL
  KAT3_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-05-04 Kyat3  kynurenine aminotransferase 3  Ccbl2  cysteine conjugate-beta lyase 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2015-07-29 Ccbl2  cysteine conjugate-beta lyase 2  LOC100361841  kynurenine aminotransferase III-like  Data Merged 737654 PROVISIONAL
2014-07-23 Ccbl2  cysteine conjugate-beta lyase 2  Kat3  kynurenine aminotransferase III  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2010-05-05 LOC100361841  kynurenine aminotransferase III-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2005-07-29 Kat3  kynurenine aminotransferase III      Symbol and Name status set to provisional 70820 PROVISIONAL