Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (1->4)-beta-D-glucan | multiple interactions | ISO | Kyat3 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of KYAT3 mRNA | CTD | PMID:36331819 | 1,1-dichloroethene | decreases expression | ISO | Kyat3 (Mus musculus) | 6480464 | vinylidene chloride results in decreased expression of KYAT3 mRNA | CTD | PMID:26682919 | 1,2-dimethylhydrazine | multiple interactions | ISO | Kyat3 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of KYAT3 mRNA | CTD | PMID:22206623 | 1,2-dimethylhydrazine | decreases expression | ISO | Kyat3 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of KYAT3 mRNA | CTD | PMID:22206623 | 1-naphthyl isothiocyanate | decreases expression | EXP | | 6480464 | 1-Naphthylisothiocyanate results in decreased expression of KAT3 mRNA and 1-Naphthylisothiocyanate results in decreased expression of KYAT3 mRNA | CTD | PMID:30723492 | 17alpha-ethynylestradiol | increases expression | ISO | Kyat3 (Mus musculus) | 6480464 | Ethinyl Estradiol results in increased expression of KYAT3 mRNA | CTD | PMID:17555576 and PMID:17942748 | 17beta-estradiol | decreases expression | ISO | KYAT3 (Homo sapiens) | 6480464 | Estradiol results in decreased expression of KYAT3 mRNA | CTD | PMID:23019147 | 17beta-estradiol | decreases expression | EXP | | 6480464 | Estradiol results in decreased expression of KYAT3 mRNA | CTD | PMID:32145629 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Kyat3 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of KYAT3 mRNA | CTD | PMID:21570461 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of KYAT3 mRNA | CTD | PMID:21215274 | 2-hydroxypropanoic acid | decreases expression | ISO | KYAT3 (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of KYAT3 mRNA | CTD | PMID:30851411 | 4,4'-diaminodiphenylmethane | decreases expression | EXP | | 6480464 | 4 more ... | CTD | PMID:30723492 | 4,4'-sulfonyldiphenol | increases expression | ISO | KYAT3 (Homo sapiens) | 6480464 | bisphenol S results in increased expression of KYAT3 protein | CTD | PMID:34186270 | 4-hydroxyphenyl retinamide | decreases expression | ISO | Kyat3 (Mus musculus) | 6480464 | Fenretinide results in decreased expression of KYAT3 mRNA | CTD | PMID:28973697 | acetamide | decreases expression | EXP | | 6480464 | acetamide results in decreased expression of KYAT3 mRNA | CTD | PMID:31881176 | aflatoxin B1 | decreases expression | EXP | | 6480464 | Aflatoxin B1 results in decreased expression of KYAT3 mRNA | CTD | PMID:23630614 | aflatoxin B1 | increases methylation | ISO | KYAT3 (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased methylation of KYAT3 gene | CTD | PMID:27153756 | aflatoxin M1 | decreases expression | ISO | KYAT3 (Homo sapiens) | 6480464 | Aflatoxin M1 results in decreased expression of KYAT3 mRNA | CTD | PMID:30928695 | antimycin A | decreases expression | ISO | KYAT3 (Homo sapiens) | 6480464 | Antimycin A results in decreased expression of KYAT3 mRNA | CTD | PMID:33512557 | aristolochic acid A | decreases expression | ISO | KYAT3 (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of KYAT3 mRNA | CTD | PMID:33212167 | Benoxacor | decreases expression | ISO | Kyat3 (Mus musculus) | 6480464 | benoxacor results in decreased expression of KYAT3 mRNA | CTD | PMID:34850242 | benzo[a]pyrene | increases methylation | ISO | KYAT3 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of KYAT3 3' UTR | CTD | PMID:27901495 | benzo[a]pyrene diol epoxide I | increases expression | ISO | KYAT3 (Homo sapiens) | 6480464 | 7 more ... | CTD | PMID:19150397 | bis(2-ethylhexyl) phthalate | decreases expression | ISO | Kyat3 (Mus musculus) | 6480464 | Diethylhexyl Phthalate results in decreased expression of KYAT3 mRNA | CTD | PMID:28085963 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of KAT3 mRNA and bisphenol A results in decreased expression of KYAT3 mRNA | CTD | PMID:25181051 more ... | bisphenol A | decreases expression | ISO | KYAT3 (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of KYAT3 protein | CTD | PMID:34186270 | bisphenol A | increases methylation | ISO | KYAT3 (Homo sapiens) | 6480464 | bisphenol A results in increased methylation of KYAT3 gene | CTD | PMID:31601247 | bisphenol A | multiple interactions | ISO | KYAT3 (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in increased methylation of KYAT3 gene | CTD | PMID:31601247 | bisphenol A | increases expression | ISO | Kyat3 (Mus musculus) | 6480464 | bisphenol A results in increased expression of KYAT3 mRNA | CTD | PMID:33221593 | Bisphenol B | increases expression | ISO | KYAT3 (Homo sapiens) | 6480464 | bisphenol B results in increased expression of KYAT3 protein | CTD | PMID:34186270 | bisphenol F | increases expression | ISO | KYAT3 (Homo sapiens) | 6480464 | bisphenol F results in increased expression of KYAT3 protein | CTD | PMID:34186270 | buspirone | increases expression | EXP | | 6480464 | Buspirone results in increased expression of KYAT3 mRNA | CTD | PMID:24136188 | cadmium atom | decreases expression | ISO | Kyat3 (Mus musculus) | 6480464 | Cadmium results in decreased expression of KYAT3 mRNA | CTD | PMID:24067728 | cadmium dichloride | increases expression | ISO | KYAT3 (Homo sapiens) | 6480464 | Cadmium Chloride results in increased expression of KYAT3 protein | CTD | PMID:24527689 | carbon nanotube | decreases expression | ISO | Kyat3 (Mus musculus) | 6480464 | Nanotubes and Carbon results in decreased expression of KYAT3 mRNA | CTD | PMID:25620056 | chlordecone | increases expression | ISO | Kyat3 (Mus musculus) | 6480464 | Chlordecone results in increased expression of KYAT3 mRNA | CTD | PMID:33711761 | chlorpyrifos | decreases expression | ISO | Kyat3 (Mus musculus) | 6480464 | Chlorpyrifos results in decreased expression of KYAT3 mRNA | CTD | PMID:37019170 | dibutyl phthalate | decreases expression | ISO | Kyat3 (Mus musculus) | 6480464 | Dibutyl Phthalate results in decreased expression of KYAT3 mRNA | CTD | PMID:21266533 | dicrotophos | decreases expression | ISO | KYAT3 (Homo sapiens) | 6480464 | dicrotophos results in decreased expression of KYAT3 mRNA | CTD | PMID:28302478 | dioxygen | decreases expression | ISO | Kyat3 (Mus musculus) | 6480464 | Oxygen deficiency results in decreased expression of KYAT3 mRNA | CTD | PMID:20880076 | doxorubicin | decreases expression | ISO | KYAT3 (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of KYAT3 mRNA | CTD | PMID:29803840 | fenpyroximate | decreases expression | ISO | KYAT3 (Homo sapiens) | 6480464 | fenpyroximate results in decreased expression of KYAT3 mRNA | CTD | PMID:33512557 | fluoranthene | multiple interactions | ISO | Kyat3 (Mus musculus) | 6480464 | [1-methylanthracene co-treated with fluoranthene] results in decreased expression of KYAT3 mRNA | CTD | PMID:28329830 | flutamide | decreases expression | EXP | | 6480464 | Flutamide results in decreased expression of KYAT3 mRNA | CTD | PMID:24136188 | folic acid | multiple interactions | ISO | Kyat3 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of KYAT3 mRNA | CTD | PMID:22206623 | formaldehyde | decreases expression | ISO | KYAT3 (Homo sapiens) | 6480464 | Formaldehyde results in decreased expression of KYAT3 mRNA | CTD | PMID:23649840 | FR900359 | increases phosphorylation | ISO | KYAT3 (Homo sapiens) | 6480464 | FR900359 results in increased phosphorylation of KYAT3 protein | CTD | PMID:37730182 | fulvestrant | multiple interactions | ISO | KYAT3 (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in increased methylation of KYAT3 gene | CTD | PMID:31601247 | gentamycin | decreases expression | EXP | | 6480464 | Gentamicins results in decreased expression of KYAT3 mRNA | CTD | PMID:33387578 | glafenine | decreases expression | EXP | | 6480464 | Glafenine results in decreased expression of KYAT3 mRNA | CTD | PMID:24136188 | indometacin | decreases expression | EXP | | 6480464 | Indomethacin results in decreased expression of KYAT3 mRNA | CTD | PMID:36868495 | inulin | multiple interactions | ISO | Kyat3 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Inulin] results in increased expression of KYAT3 mRNA | CTD | PMID:36331819 | ivermectin | decreases expression | ISO | KYAT3 (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of KYAT3 protein | CTD | PMID:32959892 | lead(0) | affects splicing | ISO | KYAT3 (Homo sapiens) | 6480464 | Lead affects the splicing of KYAT3 mRNA | CTD | PMID:28903495 | methoxychlor | affects methylation | EXP | | 6480464 | Methoxychlor affects the methylation of KYAT3 gene | CTD | PMID:35440735 | mitomycin C | affects response to substance | ISO | KYAT3 (Homo sapiens) | 6480464 | KYAT3 protein affects the susceptibility to Mitomycin | CTD | PMID:16217747 | N-nitrosodiethylamine | decreases expression | EXP | | 6480464 | Diethylnitrosamine results in decreased expression of KYAT3 mRNA | CTD | PMID:19638242 | okadaic acid | decreases expression | ISO | Kyat3 (Mus musculus) | 6480464 | Okadaic Acid results in decreased expression of KYAT3 mRNA | CTD | PMID:25270620 | paracetamol | affects response to substance | ISO | KYAT3 (Homo sapiens) | 6480464 | KYAT3 gene polymorphism affects the susceptibility to Acetaminophen | CTD | PMID:26104854 | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of KYAT3 mRNA | CTD | PMID:33387578 | paracetamol | affects expression | ISO | Kyat3 (Mus musculus) | 6480464 | Acetaminophen affects the expression of KYAT3 mRNA | CTD | PMID:17562736 | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Kyat3 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of KYAT3 mRNA and [perfluorooctane sulfonic acid co-treated with Inulin] results in increased expression of KYAT3 mRNA | CTD | PMID:36331819 | PhIP | decreases expression | EXP | | 6480464 | 2-amino-1-methyl-6-phenylimidazo(4 and 5-b)pyridine results in decreased expression of KYAT3 mRNA | CTD | PMID:33945839 | picoxystrobin | decreases expression | ISO | KYAT3 (Homo sapiens) | 6480464 | picoxystrobin results in decreased expression of KYAT3 mRNA | CTD | PMID:33512557 | pirinixic acid | multiple interactions | ISO | KYAT3 (Homo sapiens) | 6480464 | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of KYAT3 mRNA | CTD | PMID:19710929 | pirinixic acid | increases expression | ISO | Kyat3 (Mus musculus) | 6480464 | pirinixic acid results in increased expression of KYAT3 mRNA | CTD | PMID:18301758 | quercetin | decreases expression | ISO | KYAT3 (Homo sapiens) | 6480464 | Quercetin results in decreased expression of KYAT3 mRNA | CTD | PMID:21632981 | rac-lactic acid | decreases expression | ISO | KYAT3 (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of KYAT3 mRNA | CTD | PMID:30851411 | SB 431542 | multiple interactions | ISO | KYAT3 (Homo sapiens) | 6480464 | [LDN 193189 co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide co-treated with FGF2 protein] results in increased expression of KYAT3 protein | CTD | PMID:37664457 | sodium arsenite | increases expression | EXP | | 6480464 | sodium arsenite results in increased expression of KYAT3 protein | CTD | PMID:29459688 | sodium fluoride | increases expression | ISO | Kyat3 (Mus musculus) | 6480464 | Sodium Fluoride results in increased expression of KYAT3 protein | CTD | PMID:28918527 | Soman | decreases expression | EXP | | 6480464 | Soman results in decreased expression of KYAT3 mRNA | CTD | PMID:19281266 | sunitinib | increases expression | ISO | KYAT3 (Homo sapiens) | 6480464 | Sunitinib results in increased expression of KYAT3 mRNA | CTD | PMID:31533062 | tamoxifen | affects expression | ISO | Kyat3 (Mus musculus) | 6480464 | Tamoxifen affects the expression of KYAT3 mRNA | CTD | PMID:17555576 | tebufenpyrad | decreases expression | ISO | KYAT3 (Homo sapiens) | 6480464 | 4-chloro-N-((4-(1 and 1-dimethylethyl)phenyl)methyl)-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide results in decreased expression of KYAT3 mRNA | CTD | PMID:33512557 | tetrachloromethane | decreases expression | EXP | | 6480464 | Carbon Tetrachloride results in decreased expression of KYAT3 mRNA | CTD | PMID:31150632 | tetrachloromethane | decreases expression | ISO | Kyat3 (Mus musculus) | 6480464 | Carbon Tetrachloride results in decreased expression of KYAT3 mRNA | CTD | PMID:31919559 | thioacetamide | decreases expression | EXP | | 6480464 | Thioacetamide results in decreased expression of KYAT3 mRNA | CTD | PMID:23411599 and PMID:34492290 | Triptolide | decreases expression | ISO | Kyat3 (Mus musculus) | 6480464 | triptolide results in decreased expression of KYAT3 mRNA | CTD | PMID:32835833 | urethane | decreases expression | ISO | KYAT3 (Homo sapiens) | 6480464 | Urethane results in decreased expression of KYAT3 mRNA | CTD | PMID:28818685 | vancomycin | increases expression | ISO | Kyat3 (Mus musculus) | 6480464 | Vancomycin results in increased expression of KYAT3 mRNA | CTD | PMID:18930951 | |