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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Wounds and Injuries
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Accession:DOID:9001600 term browser browse the term
Definition:Damage inflicted on the body as the direct or indirect result of an external force, with or without disruption of structural continuity.
Synonyms:exact_synonym: Injuries;   Injuries, Wounds;   Injury;   Injury and Wounds;   Research Related Injuries;   Research-Related Injury;   Trauma;   Traumas;   Wound;   Wounds;   Wounds, Injury
 primary_id: MESH:D014947;   RDO:0004686
 subset: RGD_JBrowse_slim
For additional species annotation, visit the Alliance of Genome Resources.


show annotations for term's descendants           Sort by:
 
Wounds and Injuries term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alox15 arachidonate 15-lipoxygenase ISO RGD PMID:15708862 RGD:5509615 NCBI chr10:56,953,692...56,962,145
Ensembl chr10:56,953,691...56,962,161
JBrowse link
G Ankrd1 ankyrin repeat domain 1 ISO mRNA, protein:increased expression:multiple RGD PMID:15632022 RGD:5133280 NCBI chr 1:254,726,985...254,745,673
Ensembl chr 1:254,726,969...254,735,548
JBrowse link
G Arg1 arginase 1 IEP protein:increased expression:wound, fibroblast (rat) RGD PMID:12069499 RGD:634666 NCBI chr 1:21,525,421...21,537,872
Ensembl chr 1:21,525,421...21,537,863
JBrowse link
G Calca calcitonin-related polypeptide alpha ISO CTD Direct Evidence: therapeutic CTD PMID:18430544 NCBI chr 1:184,184,018...184,188,922
Ensembl chr 1:184,184,020...184,188,911
JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21192278 NCBI chr14:18,743,678...18,745,457
Ensembl chr14:18,743,685...18,745,457
JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 IEP mRNA, protein:increased expression:ligament RGD PMID:19327017 RGD:2306564 NCBI chr 4:149,261,044...149,273,891
Ensembl chr 4:149,261,044...149,273,891
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21192278 NCBI chr14:18,731,346...18,733,391
Ensembl chr14:18,731,378...18,733,391
JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21192278 NCBI chr14:18,820,168...18,839,659
Ensembl chr14:18,820,168...18,839,595
JBrowse link
G Dcn decorin IEP RGD PMID:19393425 RGD:2311417 NCBI chr 7:38,742,250...38,782,282
Ensembl chr 7:38,742,051...38,782,323
JBrowse link
G Egf epidermal growth factor IEP
ISO
CTD Direct Evidence: therapeutic CTD PMID:21967610, PMID:15885173 RGD:6906918 NCBI chr 2:68,820,616...68,895,537 JBrowse link
G Eng endoglin disease_progression ISO RGD PMID:23349951 RGD:7248769 NCBI chr 3:11,679,530...11,717,486
Ensembl chr 3:11,679,530...11,717,485
JBrowse link
G Fgf2 fibroblast growth factor 2 treatment ISO
IEP
associated with Diabetes Mellitus, Non-Insulin-Dependent
CTD Direct Evidence: therapeutic
protein:increased expression:skin
CTD PMID:11842932, PMID:16008728, PMID:21402405, PMID:23603001, PMID:12533868 RGD:2315863, RGD:8655582, RGD:8655580, RGD:2292211 NCBI chr 2:124,081,072...124,134,133
Ensembl chr 2:124,081,072...124,134,681
JBrowse link
G Gc GC, vitamin D binding protein treatment IEP
ISO
associated with Diabetes Mellitus, Experimental
CTD Direct Evidence: marker/mechanism
CTD PMID:17852808, PMID:24263389 RGD:11041807 NCBI chr14:20,267,023...20,302,577
Ensembl chr14:20,266,891...20,302,581
JBrowse link
G Hgf hepatocyte growth factor treatment ISO RGD PMID:16572191 RGD:8548635 NCBI chr 4:15,435,460...15,505,377
Ensembl chr 4:15,433,295...15,505,362
JBrowse link
G Hmox1 heme oxygenase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12649161 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hp haptoglobin treatment IEP protein:increased expression:serum
associated with Diabetes Mellitus, Experimental
RGD PMID:11521461, PMID:24263389 RGD:1626378, RGD:11041807 NCBI chr19:42,096,255...42,100,805
Ensembl chr19:42,097,995...42,100,804
JBrowse link
G Icam1 intercellular adhesion molecule 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21192278 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
JBrowse link
G Igf1 insulin-like growth factor 1 ISO
IEP
associated with Rhinosinusitis; mRNA:increased expression:nose:
protein:increased expression:skin:
RGD PMID:20713758, PMID:21296499 RGD:8548883, RGD:8549452 NCBI chr 7:28,412,123...28,491,815
Ensembl chr 7:28,412,198...28,486,609
JBrowse link
G Il10 interleukin 10 IEP RGD PMID:14715528 RGD:1598466 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G Il1a interleukin 1 alpha IEP RGD PMID:18638276 RGD:2311088 NCBI chr 3:121,824,712...121,836,122
Ensembl chr 3:121,825,412...121,836,086
JBrowse link
G Il6 interleukin 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21192278 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Lama3 laminin subunit alpha 3 ISO CTD Direct Evidence: therapeutic CTD PMID:15541073 NCBI chr18:3,704,866...3,941,215
Ensembl chr18:3,705,916...3,940,838
JBrowse link
G Lamb3 laminin subunit beta 3 ISO CTD Direct Evidence: therapeutic CTD PMID:15541073 NCBI chr13:112,031,614...112,073,187
Ensembl chr13:112,031,594...112,073,186
JBrowse link
G Lamc2 laminin subunit gamma 2 ISO CTD Direct Evidence: therapeutic CTD PMID:15541073 NCBI chr13:70,566,643...70,632,126
Ensembl chr13:70,566,643...70,626,252
JBrowse link
G Ltf lactotransferrin ISO CTD Direct Evidence: therapeutic CTD PMID:16640825 NCBI chr 8:119,290,416...119,313,261
Ensembl chr 8:119,290,416...119,313,261
JBrowse link
G Lum lumican ISO CTD Direct Evidence: therapeutic CTD PMID:24367547 NCBI chr 7:38,820,058...38,826,862
Ensembl chr 7:38,819,771...38,826,862
JBrowse link
G Mmp7 matrix metallopeptidase 7 IEP RGD PMID:9888422 RGD:9685353 NCBI chr 8:5,893,253...5,900,965
Ensembl chr 8:5,893,249...5,901,049
JBrowse link
G Mmp8 matrix metallopeptidase 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11172683 NCBI chr 8:5,768,808...5,777,741
Ensembl chr 8:5,768,811...5,778,702
JBrowse link
G Mpo myeloperoxidase ISO CTD Direct Evidence: marker/mechanism CTD PMID:21192278 NCBI chr10:75,087,892...75,098,260
Ensembl chr10:75,087,892...75,098,260
JBrowse link
G Oprl1 opioid related nociceptin receptor 1 IEP protein:decreased expression:hypothalamus: RGD PMID:11931711 RGD:9835019 NCBI chr 3:177,223,779...177,231,663
Ensembl chr 3:177,225,737...177,231,663
JBrowse link
G Optn optineurin IEP RGD PMID:16109995 RGD:7775038 NCBI chr17:77,167,700...77,218,374
Ensembl chr17:77,167,740...77,218,389
JBrowse link
G Pdgfa platelet derived growth factor subunit A IEP RGD PMID:18205704 RGD:2292158 NCBI chr12:17,734,141...17,756,186
Ensembl chr12:17,734,133...17,755,285
JBrowse link
G Pdgfb platelet derived growth factor subunit B treatment IEP
ISO
protein:increased expression:skin RGD PMID:12533868, PMID:3280728 RGD:2292211, RGD:10449501 NCBI chr 7:121,215,458...121,233,092
Ensembl chr 7:121,214,628...121,232,741
JBrowse link
G Pdgfrb platelet derived growth factor receptor beta IEP protein:increased expression:skin RGD PMID:12533868 RGD:2292211 NCBI chr18:56,364,586...56,406,381
Ensembl chr18:56,364,620...56,406,381
JBrowse link
G Plat plasminogen activator, tissue type IEP protein:increased expression:plasma (rat) RGD PMID:25423126 RGD:11541076 NCBI chr16:74,098,263...74,122,897
Ensembl chr16:74,098,260...74,122,889
JBrowse link
G Pnoc prepronociceptin IEP protein:decreased expression:hypothalamus: RGD PMID:11931711 RGD:9835019 NCBI chr15:48,805,841...48,833,071
Ensembl chr15:48,805,228...48,833,285
JBrowse link
G Postn periostin IEP protein:increased expression:skin: RGD PMID:22681660 RGD:10040991 NCBI chr 2:143,656,820...143,688,087
Ensembl chr 2:143,656,793...143,688,087
JBrowse link
G Sparc secreted protein acidic and cysteine rich IEP mRNA, protein:increased expression:skin, fibroblast RGD PMID:8245406 RGD:2300076 NCBI chr10:40,742,390...40,764,232
Ensembl chr10:40,742,400...40,764,185
JBrowse link
G Spp1 secreted phosphoprotein 1 ISO CTD Direct Evidence: therapeutic CTD PMID:9525990 NCBI chr14:6,673,686...6,679,965
Ensembl chr14:6,673,686...6,679,901
JBrowse link
G Tgfb1 transforming growth factor, beta 1 IEP
IMP
protein:increased expression:skin RGD PMID:12533868, PMID:17117936 RGD:2292211, RGD:2302090 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Tgfb2 transforming growth factor, beta 2 IMP
IEP
RGD PMID:17117936, PMID:18205704 RGD:2302090, RGD:2292158 NCBI chr13:105,039,639...105,142,010
Ensembl chr13:105,039,853...105,141,030
JBrowse link
G Tgfb3 transforming growth factor, beta 3 IEP RGD PMID:18205704 RGD:2292158 NCBI chr 6:109,913,757...109,936,217
Ensembl chr 6:109,913,757...109,935,533
JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 IEP mRNA, protein:increased expression:dorsal root ganglion RGD PMID:16683235 RGD:1600154 NCBI chr  X:1,364,771...1,369,451
Ensembl chr  X:1,364,786...1,369,384
JBrowse link
G Timp4 TIMP metallopeptidase inhibitor 4 IEP mRNA, protein:increased expression:carotid artery RGD PMID:10082471 RGD:2290470 NCBI chr 4:147,156,948...147,163,467
Ensembl chr 4:147,156,948...147,163,467
JBrowse link
G Tnf tumor necrosis factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:21192278 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Vegfa vascular endothelial growth factor A treatment ISO RGD PMID:23603001 RGD:8655580 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681
JBrowse link
Acute Heart Injury term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mfn1 mitofusin 1 IEP mRNA, protein:increased expression:heart (rat) RGD PMID:25677476 RGD:12437078 NCBI chr 2:118,929,738...118,971,689
Ensembl chr 2:118,929,738...118,973,698
JBrowse link
Acute Lung Injury term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace angiotensin I converting enzyme treatment ISO associated wit Escherichia coli Infections RGD PMID:29990483 RGD:40400897 NCBI chr10:94,170,766...94,213,831
Ensembl chr10:94,170,766...94,187,822
JBrowse link
G Ace2 angiotensin I converting enzyme 2 severity
treatment
ISO CTD Direct Evidence: therapeutic
associated with Escherichia coli Infections
associated with avian influenza;protein:decreased expression:lung (mouse)
human protein in a mouse model
CTD PMID:27302421, PMID:16001071, PMID:29990483, PMID:25391767, PMID:16001071 RGD:32716389, RGD:40400897, RGD:40818412, RGD:32716389 NCBI chr  X:32,050,734...32,095,860
Ensembl chr  X:32,049,931...32,096,016
JBrowse link
G Acvr1 activin A receptor type 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21297076 NCBI chr 3:44,432,476...44,539,680
Ensembl chr 3:44,432,471...44,522,930
JBrowse link
G Adar adenosine deaminase, RNA-specific treatment IMP RGD PMID:18520702 RGD:10755331 NCBI chr 2:189,045,551...189,085,448
Ensembl chr 2:189,062,443...189,083,236
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing treatment ISO associated with Sepsis RGD PMID:22156343, PMID:23522481 RGD:5686380, RGD:8695940 NCBI chr11:81,330,845...81,344,488
Ensembl chr11:81,330,293...81,344,488
JBrowse link
G Adra2a adrenoceptor alpha 2A IEP RGD PMID:21542970 RGD:6480481 NCBI chr 1:274,766,283...274,769,083
Ensembl chr 1:274,766,283...274,769,081
JBrowse link
G Ager advanced glycosylation end product-specific receptor IEP associated with Hyperoxia; protein:decreased expression:bronchoalveolar lavage fluid (rat) RGD PMID:23576805 RGD:7244254 NCBI chr20:4,363,152...4,366,079
Ensembl chr20:4,363,152...4,366,079
JBrowse link
G Akap12 A-kinase anchoring protein 12 IEP mRNA,protein:increased expression:lung RGD PMID:23912647 RGD:14348970 NCBI chr 1:40,816,130...40,906,582
Ensembl chr 1:40,816,107...40,906,581
JBrowse link
G Akt1 AKT serine/threonine kinase 1 severity ISO RGD PMID:23904165 RGD:38676478 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Alb albumin IDA RGD PMID:22592748 RGD:6483494 NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863
JBrowse link
G Alox15 arachidonate 15-lipoxygenase ISO RGD PMID:19752233 RGD:5509626 NCBI chr10:56,953,692...56,962,145
Ensembl chr10:56,953,691...56,962,161
JBrowse link
G Apoa1 apolipoprotein A1 ISO CTD Direct Evidence: therapeutic CTD PMID:20972769 NCBI chr 8:50,525,091...50,526,875
Ensembl chr 8:50,525,091...50,526,875
JBrowse link
G Aqp5 aquaporin 5 IEP associated with Disseminated Intravascular Coagulation;mRNA,protein:decreased expression:lung: RGD PMID:24806323 RGD:11553933 NCBI chr 7:141,249,044...141,252,576
Ensembl chr 7:141,249,044...141,252,578
JBrowse link
G Ascl1 achaete-scute family bHLH transcription factor 1 ISO CTD Direct Evidence: therapeutic CTD PMID:20554700 NCBI chr 7:28,038,662...28,040,504
Ensembl chr 7:28,038,662...28,040,510
JBrowse link
G Bax BCL2 associated X, apoptosis regulator IEP associated with Endotoxemia RGD PMID:20663300 RGD:10054109 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcl2 BCL2, apoptosis regulator IEP associated with Endotoxemia RGD PMID:20663300 RGD:10054109 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G C3 complement C3 treatment IEP RGD PMID:22763771 RGD:11040808 NCBI chr 9:9,721,137...9,747,084
Ensembl chr 9:9,721,105...9,747,167
JBrowse link
G Casp12 caspase 12 treatment IEP associated with Crush Injuries RGD PMID:30465396 RGD:34901874 NCBI chr 8:2,658,892...2,686,160
Ensembl chr 8:2,659,865...2,686,160
JBrowse link
G Casp3 caspase 3 treatment IEP RGD PMID:29755641 RGD:13782288 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp8 caspase 8 treatment IEP RGD PMID:29755641 RGD:13782288 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Cat catalase ISO CTD Direct Evidence: therapeutic CTD PMID:15612528 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Cav1 caveolin 1 treatment IEP RGD PMID:24919947 RGD:10045573 NCBI chr 4:44,597,123...44,630,206
Ensembl chr 4:44,597,123...44,630,200
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 IEP mRNA, protein:increased expression:lung RGD PMID:21767135 RGD:6480432 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ccl4 C-C motif chemokine ligand 4 IMP
IEP
ISO
mRNA, protein:increased expression:lung
protein:increased expression:respiratory system fluid/secretion
RGD PMID:10679105, PMID:21767135, PMID:21906407 RGD:68880, RGD:6480432, RGD:5683874 NCBI chr10:70,870,926...70,886,357
Ensembl chr10:70,884,531...70,886,355
JBrowse link
G Ccr1 C-C motif chemokine receptor 1 ISO associated with Pancreatitis RGD PMID:17312463 RGD:5688151 NCBI chr 8:132,996,646...133,002,201
Ensembl chr 8:132,996,649...133,002,201
JBrowse link
G Cd36 CD36 molecule ISO associated with Malaria RGD PMID:18483551 RGD:6893505 NCBI chr 4:14,150,309...14,191,498
Ensembl chr 4:14,001,761...14,249,749
JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 ISO associated with Sepsis;mRNA:increased expression:lung RGD PMID:10069420 RGD:5135253 NCBI chr14:18,743,678...18,745,457
Ensembl chr14:18,743,685...18,745,457
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 ISO
IEP
mRNA, protein:increased expression:lung
CTD Direct Evidence: marker/mechanism
protein:increased expression:respiratory system fluid/secretion
associated with Sepsis;mRNA:increased expression:lung
CTD PMID:27525872, PMID:15557650, PMID:19106808, PMID:10069420 RGD:5135247, RGD:5147925, RGD:5135253 NCBI chr14:18,731,346...18,733,391
Ensembl chr14:18,731,378...18,733,391
JBrowse link
G Cxcl6 C-X-C motif chemokine ligand 6 ISO
IMP
mRNA, protein:increased expression:lung
associated with Reperfusion Injury
RGD PMID:15557650, PMID:7814607 RGD:5135247, RGD:5135256 NCBI chr14:18,860,201...18,920,839
Ensembl chr14:18,860,264...18,862,407
JBrowse link
G Cxcr2 C-X-C motif chemokine receptor 2 treatment ISO associated with Pancreatitis RGD PMID:17014919 RGD:7257703 NCBI chr 9:81,427,275...81,435,065
Ensembl chr 9:81,427,730...81,434,102
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 ISO
IEP
mRNA:increased expression:lung RGD PMID:18367723, PMID:16882535 RGD:5135235, RGD:5147744 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 IEP RGD PMID:16882535 RGD:5147744 NCBI chr 7:99,142,431...99,183,540
Ensembl chr 7:99,142,450...99,181,783
JBrowse link
G Cysltr1 cysteinyl leukotriene receptor 1 treatment ISO associated with Endotoxemia RGD PMID:27703200 RGD:40903067 NCBI chr  X:77,671,028...77,700,491
Ensembl chr  X:77,674,150...77,700,269
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 treatment IEP associated with Crush Injuries RGD PMID:30465396 RGD:34901874 NCBI chr 7:70,578,564...70,585,074
Ensembl chr 7:70,580,198...70,585,084
JBrowse link
G Edn1 endothelin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16625121 NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324
JBrowse link
G Egfr epidermal growth factor receptor ISO RGD PMID:20935109 RGD:5131862 NCBI chr14:99,919,485...100,104,136
Ensembl chr14:99,919,485...100,098,796
JBrowse link
G Elane elastase, neutrophil expressed treatment IMP
IEP
associated with Shock, Hemorrhagic;
protein:increased expression:perfusate:
RGD PMID:15257085, PMID:17203197, PMID:18283562 RGD:10450548, RGD:10450587, RGD:10450585 NCBI chr 7:12,638,320...12,640,168
Ensembl chr 7:12,638,322...12,640,232
JBrowse link
G Ephx1 epoxide hydrolase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26840748 NCBI chr13:99,271,390...99,300,580
Ensembl chr13:99,271,366...99,300,579
JBrowse link
G Ephx2 epoxide hydrolase 2 IDA RGD PMID:22051199 RGD:5688354 NCBI chr15:42,757,241...42,794,211
Ensembl chr15:42,757,235...42,794,279
JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 treatment IEP associated with Crush Injuries RGD PMID:30465396 RGD:34901874 NCBI chr10:94,588,555...94,682,072
Ensembl chr10:94,588,555...94,681,914
JBrowse link
G F2 coagulation factor II IDA RGD PMID:22804886 RGD:7387313 NCBI chr 3:80,529,468...80,542,993
Ensembl chr 3:80,529,428...80,543,031
JBrowse link
G F3 coagulation factor III, tissue factor IEP protein:increased expression: respiratory system fluid/secretion RGD PMID:21964405 RGD:11341740 NCBI chr 2:225,310,686...225,322,281
Ensembl chr 2:225,310,624...225,322,272
JBrowse link
G Fadd Fas associated via death domain treatment IEP associated with Shock, Hemorrhagic RGD PMID:24122010 RGD:11341811 NCBI chr 1:217,746,176...217,748,581
Ensembl chr 1:217,742,929...217,748,628
JBrowse link
G Fas Fas cell surface death receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:11778176 NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790
JBrowse link
G Faslg Fas ligand ISO CTD Direct Evidence: marker/mechanism CTD PMID:11778176 NCBI chr13:79,696,811...79,717,581
Ensembl chr13:79,698,445...79,705,705
JBrowse link
G Fcgr1a Fc fragment of IgG receptor Ia IMP RGD PMID:19106808 RGD:5147925 NCBI chr 2:198,430,536...198,439,453
Ensembl chr 2:198,430,530...198,458,041
JBrowse link
G Fcgr2a Fc fragment of IgG receptor IIa IMP RGD PMID:19106808 RGD:5147925 NCBI chr13:91,146,878...91,163,691
Ensembl chr13:91,168,973...91,198,036
Ensembl chr13:91,168,973...91,198,036
JBrowse link
G Fcgr2b Fc fragment of IgG receptor IIb treatment IMP RGD PMID:19106808 RGD:5147925 NCBI chr13:89,329,298...89,343,916
Ensembl chr13:89,327,794...89,433,815
JBrowse link
G Fga fibrinogen alpha chain IEP protein:increased expression:blood (rat) RGD PMID:22804886 RGD:7387313 NCBI chr 2:181,997,562...182,013,726
Ensembl chr 2:182,006,242...182,013,763
JBrowse link
G Flt1 Fms related receptor tyrosine kinase 1 IMP associated with Endotoxemia RGD PMID:21528367 RGD:5684427 NCBI chr12:9,033,993...9,205,886
Ensembl chr12:9,034,308...9,205,905
JBrowse link
G Gja1 gap junction protein, alpha 1 treatment IEP RGD PMID:23576849 RGD:8662452 NCBI chr20:37,876,650...37,889,097
Ensembl chr20:37,876,650...37,889,089
JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 IEP protein:decreased expression:lung (rat) RGD PMID:25581610 RGD:13504847 NCBI chr 1:263,246,248...263,269,762
Ensembl chr 1:263,246,248...263,269,762
JBrowse link
G Gsr glutathione-disulfide reductase IEP RGD PMID:7896613 RGD:7257562 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
JBrowse link
G Gzmb granzyme B ISO RGD PMID:20018616 RGD:5135517 NCBI chr15:35,413,862...35,417,293
Ensembl chr15:35,413,793...35,417,316
JBrowse link
G Hmgb1 high mobility group box 1 treatment IEP associated with Endotoxemia
associated with Crush Injuries
associated with Burns
RGD PMID:19766246, PMID:30465396, PMID:23874764 RGD:4892587, RGD:34901874, RGD:10402098 NCBI chr12:7,082,529...7,090,246
Ensembl chr16:37,500,017...37,502,237
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase ISO RGD PMID:16922808 RGD:5508470 NCBI chr 2:27,480,224...27,500,654
Ensembl chr 2:27,480,226...27,500,654
JBrowse link
G Hmox1 heme oxygenase 1 treatment IMP
IEP
associated with Reperfusion Injury RGD PMID:20850789, PMID:20360627 RGD:4145326, RGD:4140418 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hnrnpc heterogeneous nuclear ribonucleoprotein C ISO protein:altered localization:lung (mouse) RGD PMID:19029002 RGD:10054390 NCBI chr15:28,486,605...28,517,353
Ensembl chr15:28,486,617...28,517,353
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 treatment IEP associated with Crush Injuries RGD PMID:30465396 RGD:34901874 NCBI chr 3:13,838,304...13,842,763
Ensembl chr 3:13,838,304...13,842,762
JBrowse link
G Icam1 intercellular adhesion molecule 1 treatment IEP
ISO
CTD Direct Evidence: marker/mechanism CTD PMID:17973899 PMID:27525872, PMID:20569121 RGD:8547719 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
JBrowse link
G Ido1 indoleamine 2,3-dioxygenase 1 treatment ISO RGD PMID:25278421 RGD:39939031 NCBI chr16:72,216,326...72,228,098
Ensembl chr16:72,216,326...72,228,098
JBrowse link
G Ifng interferon gamma IEP RGD PMID:21767135 RGD:6480432 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Il10 interleukin 10 treatment
no_association
IDA
ISO
IEP
DNA:SNP:promoter:rs3021097 (human)
DNA:SNP:promoter:-1082G>A (rs1800896) (human)
associated with Reperfusion Injury;protein:increased expression:lung, plasma
RGD PMID:23902576, PMID:30412745, PMID:30412745, PMID:23801594 RGD:7364984, RGD:14975158, RGD:14975158, RGD:7365008 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G Il13 interleukin 13 IEP mRNA:increased expression:lung RGD PMID:15461830 RGD:4145512 NCBI chr10:38,982,909...38,985,466
Ensembl chr10:38,982,909...38,985,466
JBrowse link
G Il17a interleukin 17A ISO CTD Direct Evidence: marker/mechanism CTD PMID:28600744 NCBI chr 9:26,841,299...26,844,786
Ensembl chr 9:26,841,299...26,844,786
JBrowse link
G Il18 interleukin 18 treatment IEP associated with Myocardial Reperfusion Injury RGD PMID:24223666 RGD:8655952 NCBI chr 8:55,009,666...55,016,286
Ensembl chr 8:54,993,859...55,016,299
JBrowse link
G Il1b interleukin 1 beta ISO
IDA
IEP
protein:increased expression:lung
mRNA, protein:increased expression:lung
protein:increased expression:serum
RGD PMID:20153312, PMID:22982561, PMID:21767135, PMID:20663306, PMID:8613550 RGD:4142807, RGD:7204498, RGD:6480432, RGD:4142531, RGD:4143193 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il1rl1 interleukin 1 receptor-like 1 ISO CTD Direct Evidence: therapeutic CTD PMID:21352201, PMID:21352201 RGD:5144222 NCBI chr 9:47,133,483...47,184,316
Ensembl chr 9:47,134,034...47,182,170
JBrowse link
G Il1rn interleukin 1 receptor antagonist IMP
IEP
mRNA:increased expression:lung RGD PMID:8613550, PMID:15970097 RGD:4143193, RGD:4143168 NCBI chr 3:1,449,778...1,468,624
Ensembl chr 3:1,452,644...1,468,614
JBrowse link
G Il2 interleukin 2 IEP protein:increased expression:respiratory system fluid/secretion RGD PMID:21767135 RGD:6480432 NCBI chr 2:123,847,150...123,851,854
Ensembl chr 2:123,847,150...123,851,854
JBrowse link
G Il22 interleukin 22 ISO RGD PMID:20498020 RGD:4888524 NCBI chr 7:61,236,037...61,240,502
Ensembl chr 7:61,236,037...61,240,502
JBrowse link
G Il4 interleukin 4 treatment IEP RGD PMID:24681349 RGD:10402798 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531
JBrowse link
G Il6 interleukin 6 IEP protein:increased expression:bronchoalveolar lavage, blood, lung (rat) RGD PMID:19995278 RGD:11062103 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Irak3 interleukin-1 receptor-associated kinase 3 ISO mRNA, protein:increased expression:lung (mouse) RGD PMID:21577093 RGD:36049795 NCBI chr 7:64,922,830...64,982,224
Ensembl chr 7:64,923,615...64,982,281
JBrowse link
G Itgb2 integrin subunit beta 2 IMP RGD PMID:1374449 RGD:6482199 NCBI chr20:11,777,773...11,815,647
Ensembl chr20:11,777,783...11,815,647
JBrowse link
G Jak3 Janus kinase 3 ISO RGD PMID:22359619 RGD:11531100 NCBI chr16:20,107,471...20,120,678
Ensembl chr16:20,109,200...20,120,668
JBrowse link
G Kdr kinase insert domain receptor IEP associated with Endotoxemia;mRNA, protein:decreased expression:lung RGD PMID:21528367 RGD:5684427 NCBI chr14:34,727,677...34,787,127
Ensembl chr14:34,727,623...34,787,183
JBrowse link
G Ltb4r2 leukotriene B4 receptor 2 severity ISO associated with Endotoxemia RGD PMID:27703200 RGD:40903067 NCBI chr15:34,446,478...34,448,220
Ensembl chr15:34,446,878...34,447,954
JBrowse link
G Mfn1 mitofusin 1 IEP mRNA, protein:altered expression:lung (rat) RGD PMID:25560372 RGD:12437080 NCBI chr 2:118,929,738...118,971,689
Ensembl chr 2:118,929,738...118,973,698
JBrowse link
G Mfn2 mitofusin 2 IEP mRNA, protein:increased expression:lung (rat) RGD PMID:25560372 RGD:12437080 NCBI chr 5:164,684,244...164,715,414
Ensembl chr 5:164,684,509...164,714,145
JBrowse link
G Mir155 microRNA 155 treatment ISO
IMP
associated with sepsis;miRNA:increased expression:lung
associated with Sepsis
RGD PMID:30220274, PMID:27371731, PMID:27371731, PMID:28125526, PMID:31949845 RGD:21066348, RGD:11566124, RGD:11566124, RGD:24922218, RGD:21408593 NCBI chr11:24,176,603...24,176,667
Ensembl chr11:24,176,603...24,176,667
JBrowse link
G Mir21 microRNA 21 IEP RNA:increased expression:lung RGD PMID:30542412 RGD:41410885 NCBI chr10:73,902,210...73,902,301
Ensembl chr10:73,902,210...73,902,301
JBrowse link
G Mir223 microRNA 223 severity
treatment
ISO
IEP
RGD PMID:28931657, PMID:32226458 RGD:21408568, RGD:26884341 NCBI chr  X:65,367,812...65,367,921
Ensembl chr  X:65,367,812...65,367,921
JBrowse link
G Mir330 microRNA 330 IEP associated with Disseminated Intravascular Coagulation;RNA:increased expression:lung: RGD PMID:24806323 RGD:11553933 NCBI chr 1:80,092,681...80,092,777
Ensembl chr 1:80,092,681...80,092,777
JBrowse link
G Mir96 microRNA 96 IEP associated with Disseminated Intravascular Coagulation;RNA:increased expression:lung: RGD PMID:24806323 RGD:11553933 NCBI chr 4:57,463,366...57,463,471
Ensembl chr 4:57,463,366...57,463,471
JBrowse link
G Mmp2 matrix metallopeptidase 2 IEP RGD PMID:23040778 RGD:13207316 NCBI chr19:15,542,771...15,570,589
Ensembl chr19:15,542,765...15,570,611
JBrowse link
G Mmp7 matrix metallopeptidase 7 IEP associated with Sepsis RGD PMID:21567117 RGD:9685338 NCBI chr 8:5,893,253...5,900,965
Ensembl chr 8:5,893,249...5,901,049
JBrowse link
G Mmp9 matrix metallopeptidase 9 IEP RGD PMID:23040778 RGD:13207316 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Mpo myeloperoxidase ISO associated with Kidney Reperfusion Injury; protein:increased expression:lung RGD PMID:22092133 RGD:6909173 NCBI chr10:75,087,892...75,098,260
Ensembl chr10:75,087,892...75,098,260
JBrowse link
G Mt1 metallothionein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16166738 NCBI chr19:11,301,991...11,303,007
Ensembl chr17:78,793,336...78,793,724
JBrowse link
G Mt2A metallothionein 2A ISO CTD Direct Evidence: marker/mechanism CTD PMID:16166738 NCBI chr19:11,307,966...11,308,740
Ensembl chr19:11,307,967...11,308,740
JBrowse link
G Mylk myosin light chain kinase ISO associated with Sepsis
CTD Direct Evidence: marker/mechanism
CTD PMID:19374788, PMID:16399953 RGD:1581052 NCBI chr11:69,013,060...69,260,039
Ensembl chr11:69,013,050...69,223,158
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 ISO CTD Direct Evidence: therapeutic CTD PMID:24812154 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Ngf nerve growth factor ISO RGD PMID:17673270 RGD:5144065 NCBI chr 2:204,886,158...204,939,523
Ensembl chr 2:204,886,202...204,940,453
JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 treatment IDA associated with Sepsis RGD PMID:22575870 RGD:8547530 NCBI chr19:19,342,061...19,389,366
Ensembl chr19:19,332,594...19,377,492
JBrowse link
G Nos2 nitric oxide synthase 2 IMP RGD PMID:16882535 RGD:5147744 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Nppa natriuretic peptide A ISO RGD PMID:23422200 RGD:7247713 NCBI chr 5:164,808,407...164,809,716
Ensembl chr 5:164,808,323...164,809,705
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 treatment IEP
IDA
RGD PMID:24669282, PMID:28065220 RGD:11035223, RGD:13442501 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Opa1 OPA1, mitochondrial dynamin like GTPase IEP mRNA, protein:altered expression:lung (rat) RGD PMID:25560372 RGD:12437080 NCBI chr11:74,717,600...74,793,902
Ensembl chr11:74,720,254...74,793,803
JBrowse link
G P2ry12 purinergic receptor P2Y12 IMP associated with Shock, Hemorrhagic RGD PMID:21841533 RGD:6480522 NCBI chr 2:149,440,807...149,482,592
Ensembl chr 2:149,441,598...149,444,548
JBrowse link
G Pak1 p21 (RAC1) activated kinase 1 IDA DNA:hypermethylation RGD PMID:23546543 RGD:11533951 NCBI chr 1:162,768,156...162,883,356
Ensembl chr 1:162,768,156...162,883,355
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 ISO associated with Pancreatitis, Experimental, Acute RGD PMID:16127429 RGD:11075069 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Pawr pro-apoptotic WT1 regulator IEP mRNA,protein:increased expression:lung,blood vessel: RGD PMID:17136598 RGD:9835397 NCBI chr 7:51,273,764...51,353,700
Ensembl chr 7:51,273,771...51,353,068
JBrowse link
G Pecam1 platelet and endothelial cell adhesion molecule 1 IDA RGD PMID:22592748 RGD:6483494 NCBI chr10:94,850,971...94,913,202 JBrowse link
G Pfkfb3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 ISO associated with Endotoxemia;mRNA, protein:increased expression:lung (mouse) RGD PMID:31167111 RGD:41410778 NCBI chr17:70,632,778...70,713,736
Ensembl chr17:70,684,134...70,713,726
JBrowse link
G Pik3cg phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma ISO associated with endotoxemia RGD PMID:22198681, PMID:11714830 RGD:6482677, RGD:38599213 NCBI chr 6:51,465,696...51,501,234
Ensembl chr 6:51,465,908...51,498,337
JBrowse link
G Pla2g2a phospholipase A2 group IIA severity IEP RGD PMID:19235614 RGD:6482722 NCBI chr 5:157,282,650...157,285,295
Ensembl chr 5:157,282,669...157,285,328
JBrowse link
G Plau plasminogen activator, urokinase treatment IDA associated with Endotoxemia RGD PMID:21473829, PMID:23324284 RGD:5147760, RGD:7241552 NCBI chr15:3,644,296...3,650,765
Ensembl chr15:3,644,769...3,650,819
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma IEP
ISO
protein:decreased expression:lung (rat)
CTD Direct Evidence: therapeutic
CTD PMID:21153920, PMID:16083301 RGD:8553030 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G Prkaa1 protein kinase AMP-activated catalytic subunit alpha 1 ISO RGD PMID:21595935 RGD:6484539 NCBI chr 2:54,857,688...54,893,404
Ensembl chr 2:54,857,688...54,893,404
JBrowse link
G Proc protein C, inactivator of coagulation factors Va and VIIIa treatment ISO associated with Pseudomonas Infections
associated with Intestinal Reperfusion Injury
RGD PMID:16553944, PMID:18367148 RGD:11100043, RGD:11250405 NCBI chr18:24,918,402...24,928,822
Ensembl chr18:24,918,398...24,929,091
JBrowse link
G Procr protein C receptor treatment IEP RGD PMID:20095324 RGD:13515130 NCBI chr 3:151,285,321...151,289,581
Ensembl chr 3:151,285,249...151,289,595
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 ISO
IEP
protein:increased expression:lung RGD PMID:20926798, PMID:19567182 RGD:5135287, RGD:5135496 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Scgb1a1 secretoglobin family 1A member 1 IEP
ISO
protein:decreased expression:lung RGD PMID:18420837, PMID:16226776 RGD:5143982, RGD:5144142 NCBI chr 1:225,279,698...225,283,246
Ensembl chr 1:225,279,676...225,283,326
JBrowse link
G Serpinc1 serpin family C member 1 treatment ISO associated with Endotoxemia RGD PMID:17940748 RGD:11035256 NCBI chr13:78,806,107...78,820,375
Ensembl chr13:78,805,347...78,833,192
JBrowse link
G Serpine1 serpin family E member 1 treatment IDA
IEP
associated with Shock, Hemorrhagic;mRNA:increased expression:lung (rat)
associated with Sepsis
RGD PMID:25934465, PMID:10745022, PMID:18182560 RGD:11075078, RGD:11080967, RGD:11080962 NCBI chr12:22,641,104...22,651,482
Ensembl chr12:22,641,104...22,651,482
JBrowse link
G Serping1 serpin family G member 1 treatment ISO RGD PMID:11685347 RGD:8661650 NCBI chr 3:72,161,230...72,171,109
Ensembl chr 3:72,161,189...72,171,078
JBrowse link
G Sftpa1 surfactant protein A1 ISO mRNA, protein:increased expression:pneumocyte RGD PMID:8569184 RGD:4143451 NCBI chr16:18,716,019...18,719,404
Ensembl chr16:18,716,019...18,719,403
JBrowse link
G Sftpd surfactant protein D ISO CTD Direct Evidence: therapeutic CTD PMID:30060251 NCBI chr16:18,753,535...18,766,100
Ensembl chr16:18,745,458...18,766,174
JBrowse link
G Slpi secretory leukocyte peptidase inhibitor severity
treatment
IMP
IEP
associated with Endotoxemia RGD PMID:10092827, PMID:25466948 RGD:9999422, RGD:9999425 NCBI chr 3:160,799,979...160,802,228
Ensembl chr 3:160,799,981...160,802,433
JBrowse link
G Tac1 tachykinin, precursor 1 ISO RGD PMID:19797759 RGD:5147812 NCBI chr 4:33,638,853...33,646,819
Ensembl chr 4:33,638,709...33,646,819
JBrowse link
G Tacr1 tachykinin receptor 1 ISO mRNA:increased expression:lung RGD PMID:18523300 RGD:5147819 NCBI chr 4:113,247,236...113,416,139
Ensembl chr 4:113,247,795...113,414,504
JBrowse link
G Tff1 trefoil factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19880587 NCBI chr20:9,892,124...9,895,984
Ensembl chr20:9,892,124...9,895,984
JBrowse link
G Tff2 trefoil factor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19880587 NCBI chr20:9,872,669...9,876,008
Ensembl chr20:9,872,680...9,876,008
JBrowse link
G Tgfb1 transforming growth factor, beta 1 treatment ISO CTD Direct Evidence: marker/mechanism CTD PMID:16100012, PMID:25278421 RGD:39939031 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Thbd thrombomodulin treatment ISO
IEP
associated with Endotoxemia RGD PMID:19342415, PMID:20095324, PMID:19536047 RGD:5131887, RGD:13515130, RGD:5685372 NCBI chr 3:142,748,673...142,752,325
Ensembl chr 3:142,748,674...142,752,325
JBrowse link
G Timp2 TIMP metallopeptidase inhibitor 2 severity IMP RGD PMID:10092827 RGD:9999422 NCBI chr10:107,338,465...107,386,072
Ensembl chr10:107,338,465...107,386,072
JBrowse link
G Tlr4 toll-like receptor 4 IEP RGD PMID:19567182 RGD:5135496 NCBI chr 5:82,587,424...82,601,056
Ensembl chr 5:82,587,420...82,601,052
JBrowse link
G Tnf tumor necrosis factor treatment
no_association
IEP
ISO
mRNA, protein:increased expression:lung
associated with Liver Reperfusion Injury
DNA:SNP:promoter:rs1799964 (human)
DNA:SNP:promoter:-308G>A (rs1800629) (human)
protein:increased expression:respiratory system fluid/secretion
RGD PMID:21767135, PMID:11129814, PMID:30412745, PMID:30412745, PMID:19106808 RGD:6480432, RGD:14995473, RGD:14975158, RGD:14975158, RGD:5147925 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tnfaip6 TNF alpha induced protein 6 ISO CTD Direct Evidence: therapeutic CTD PMID:26313688 NCBI chr 3:37,545,238...37,564,704
Ensembl chr 3:37,545,238...37,564,699
JBrowse link
G Txn1 thioredoxin 1 ISO CTD Direct Evidence: therapeutic CTD PMID:16298680 NCBI chr 5:75,049,735...75,057,731
Ensembl chr 5:75,049,747...75,057,752
JBrowse link
G Vegfa vascular endothelial growth factor A IEP associated with Endotoxemia;mRNA, protein:altered expression:lung, plasma RGD PMID:21528367 RGD:5684427 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681
JBrowse link
G Vip vasoactive intestinal peptide IDA
ISO
associated with Endotoxemia
CTD Direct Evidence: therapeutic
CTD PMID:8643465, PMID:20441697 RGD:4145303 NCBI chr 1:42,169,307...42,177,582
Ensembl chr 1:42,169,501...42,177,582
JBrowse link
G Xdh xanthine dehydrogenase treatment IEP RGD PMID:9655743 RGD:13209002 NCBI chr 6:25,149,570...25,211,273
Ensembl chr 6:25,149,235...25,211,494
JBrowse link
G Zc3h12a zinc finger CCCH type containing 12A severity ISO associated with toxic shock syndrome RGD PMID:23422584 RGD:39938961 NCBI chr 5:143,111,342...143,120,131
Ensembl chr 5:143,111,074...143,120,165
JBrowse link
anthracosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp1a4 ATPase Na+/K+ transporting subunit alpha 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29394417 NCBI chr13:90,605,792...90,642,032
Ensembl chr13:90,605,794...90,641,772
JBrowse link
G Flacc1 flagellum associated containing coiled-coil domains 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29394417 NCBI chr 9:65,665,663...65,693,822
Ensembl chr 9:65,665,664...65,693,822
JBrowse link
G Il1a interleukin 1 alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:20005085 NCBI chr 3:121,824,712...121,836,122
Ensembl chr 3:121,825,412...121,836,086
JBrowse link
G Il1b interleukin 1 beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:20005085 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il1rn interleukin 1 receptor antagonist ISO CTD Direct Evidence: marker/mechanism CTD PMID:20005085 NCBI chr 3:1,449,778...1,468,624
Ensembl chr 3:1,452,644...1,468,614
JBrowse link
G Rbm26 RNA binding motif protein 26 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29394417 NCBI chr15:89,262,683...89,339,323
Ensembl chr15:89,266,710...89,339,323
JBrowse link
G Tnf tumor necrosis factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:20005085 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
Anthracycline-induced Cardiotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A susceptibility ISO DNA:missense mutation:cds:p.G671V (human) RGD PMID:16330681 RGD:11041175 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Capn2 calpain 2 treatment IEP RGD PMID:25634181 RGD:13792617 NCBI chr13:100,878,649...100,928,811
Ensembl chr13:100,878,650...100,928,811
JBrowse link
G Ercc2 ERCC excision repair 2, TFIIH core complex helicase subunit ISO associated with Leukemia, Myeloid, Acute;DNA:SNP:exon:p.K751Q (rs13181) (human) RGD PMID:24284041 RGD:11252190 NCBI chr 1:80,293,574...80,307,334
Ensembl chr 1:80,293,566...80,307,344
JBrowse link
Aortic Rupture term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp7a ATPase copper transporting alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:2346371 PMID:25449986 NCBI chr  X:77,076,085...77,193,644
Ensembl chr  X:77,076,106...77,193,644
JBrowse link
G Edn2 endothelin 2 ISO RGD PMID:11947982 RGD:1580915 NCBI chr 5:139,098,472...139,106,396
Ensembl chr 5:139,100,898...139,105,792
JBrowse link
G Fbn1 fibrillin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18178469 NCBI chr 3:117,569,708...117,766,160
Ensembl chr 3:117,569,697...117,766,120
JBrowse link
G Mmp2 matrix metallopeptidase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18178469 NCBI chr19:15,542,771...15,570,589
Ensembl chr19:15,542,765...15,570,611
JBrowse link
G Mmp9 matrix metallopeptidase 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18178469 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Npr1 natriuretic peptide receptor 1 ISO associated with Hypertension RGD PMID:9405681 RGD:737701 NCBI chr 2:189,840,403...189,857,032
Ensembl chr 2:189,840,403...189,856,090
JBrowse link
G Vkorc1 vitamin K epoxide reductase complex, subunit 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16549638 NCBI chr 1:199,338,785...199,341,306
Ensembl chr 1:199,337,138...199,341,302
JBrowse link
asbestosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arg1 arginase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26699812 NCBI chr 1:21,525,421...21,537,872
Ensembl chr 1:21,525,421...21,537,863
JBrowse link
G Atf6 activating transcription factor 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25324550 NCBI chr13:89,053,457...89,242,531
Ensembl chr13:89,055,983...89,242,443
JBrowse link
G Cfd complement factor D ISO CTD Direct Evidence: marker/mechanism CTD PMID:22832039 NCBI chr 7:12,634,216...12,635,939
Ensembl chr 7:12,634,216...12,635,943
JBrowse link
G Clca1 chloride channel accessory 1 ISO mRNA, protein:increased expression:lung RGD PMID:17637221 RGD:4145655 NCBI chr 2:250,897,980...250,923,711
Ensembl chr 2:250,897,969...250,923,744
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 ISO mRNA:decreased expression:leukocyte RGD PMID:20514434 RGD:4892076 NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25324550 NCBI chr 7:70,578,564...70,585,074
Ensembl chr 7:70,580,198...70,585,084
JBrowse link
G Ephx1 epoxide hydrolase 1 susceptibility ISO DNA:SNP:exon:p.Y113H (rs1051740) (human) RGD PMID:17159790 RGD:4889408 NCBI chr13:99,271,390...99,300,580
Ensembl chr13:99,271,366...99,300,579
JBrowse link
G Gstm1 glutathione S-transferase mu 1 susceptibility ISO DNA:deletion: : RGD PMID:9055949 RGD:5490588 NCBI chr 2:210,803,869...210,809,461
Ensembl chr 2:210,803,869...210,809,306
JBrowse link
G Gstt1 glutathione S-transferase theta 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17563610 NCBI chr20:13,799,102...13,816,527
Ensembl chr20:13,799,102...13,816,526
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25324550 NCBI chr 3:13,838,304...13,842,763
Ensembl chr 3:13,838,304...13,842,762
JBrowse link
G Il1b interleukin 1 beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:8473757 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24142982 NCBI chr10:45,884,324...45,918,290
Ensembl chr10:45,893,018...45,918,254
JBrowse link
G Nos2 nitric oxide synthase 2 ISO
IEP
CTD Direct Evidence: marker/mechanism
mRNA,protein:increased expression:lung
CTD PMID:12160931, PMID:12160931, PMID:12051993 RGD:4891441, RGD:4891438 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Prdx1 peroxiredoxin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22537621 NCBI chr 5:135,536,413...135,551,986
Ensembl chr 5:135,536,413...135,551,990
JBrowse link
G Prdx2 peroxiredoxin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22537621 NCBI chr19:26,084,816...26,090,095
Ensembl chr19:26,084,903...26,090,094
JBrowse link
G Serpina1 serpin family A member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12368052 NCBI chr 6:127,610,241...127,632,265
Ensembl chr 6:127,610,243...127,632,265
JBrowse link
G Spp1 secreted phosphoprotein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16221779 PMID:21514415 NCBI chr14:6,673,686...6,679,965
Ensembl chr14:6,673,686...6,679,901
JBrowse link
G Tnc tenascin C ISO protein:increased expression:pleura RGD PMID:10950882 RGD:4889594 NCBI chr 5:79,789,686...79,874,555
Ensembl chr 5:79,789,671...79,874,671
JBrowse link
G Tnf tumor necrosis factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:8473757 PMID:20486865 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tpm4 tropomyosin 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22537621 NCBI chr16:19,385,810...19,399,851
Ensembl chr16:19,385,736...19,399,903
JBrowse link
Asphyxia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hif1a hypoxia inducible factor 1 subunit alpha IEP mRNA, protein:increased expression:myocardium, lung (rat) RGD PMID:17285858 RGD:9068458 NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052
JBrowse link
G Ift80 intraflagellar transport 80 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17468754 NCBI chr 2:165,506,878...165,600,748
Ensembl chr 2:165,505,810...165,600,748
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit ISO RGD PMID:18620825 RGD:4890002 NCBI chr 5:114,011,184...114,014,277
Ensembl chr 5:114,011,189...114,014,277
JBrowse link
G Sox4 SRY-box transcription factor 4 IDA RGD PMID:12011571 RGD:1581119 NCBI chr17:37,615,022...37,619,728 JBrowse link
asphyxia neonatorum term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cat catalase ISO CTD Direct Evidence: marker/mechanism CTD PMID:17963755 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Ercc2 ERCC excision repair 2, TFIIH core complex helicase subunit IEP mRNA:increased expression:brain RGD PMID:9763211 RGD:2302855 NCBI chr 1:80,293,574...80,307,334
Ensembl chr 1:80,293,566...80,307,344
JBrowse link
G Ercc3 ERCC excision repair 3, TFIIH core complex helicase subunit IEP mRNA:decreased expression:brain RGD PMID:9763211 RGD:2302855 NCBI chr18:25,037,668...25,068,380
Ensembl chr18:25,037,625...25,068,389
JBrowse link
G Gstm1 glutathione S-transferase mu 1 severity ISO DNA:deletion, haplotype:: (human) RGD PMID:21058530 RGD:12792218 NCBI chr 2:210,803,869...210,809,461
Ensembl chr 2:210,803,869...210,809,306
JBrowse link
G Htra2 HtrA serine peptidase 2 treatment IEP protein:increased expression:kidney: RGD PMID:20704803 RGD:10402931 NCBI chr 4:113,883,671...113,886,833
Ensembl chr 4:113,883,670...113,886,994
JBrowse link
G Map2 microtubule-associated protein 2 IEP RGD PMID:21858873 RGD:6483085 NCBI chr 9:73,204,753...73,462,965
Ensembl chr 9:73,319,710...73,462,972
JBrowse link
G Pdia3 protein disulfide isomerase family A, member 3 IEP protein:increased expression:hippocampus: RGD PMID:15453273 RGD:9999183 NCBI chr 3:113,376,983...113,400,707
Ensembl chr 3:113,376,983...113,400,707
JBrowse link
G Psen1 presenilin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17963755 NCBI chr 6:107,169,514...107,221,000
Ensembl chr 6:107,169,528...107,216,798
JBrowse link
G Psen2 presenilin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17963755 NCBI chr13:98,513,600...98,539,347
Ensembl chr13:98,513,570...98,530,724
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17963755 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G S100b S100 calcium binding protein B ISO protein:increased expression:urine RGD PMID:14707571 RGD:5508819 NCBI chr20:13,130,633...13,142,856
Ensembl chr20:13,130,636...13,142,856
JBrowse link
G Sod1 superoxide dismutase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17963755 NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862
JBrowse link
G Sod2 superoxide dismutase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17963755 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
JBrowse link
G Xrcc1 X-ray repair cross complementing 1 IEP mRNA:increased expression:brain RGD PMID:9763211 RGD:2302855 NCBI chr 1:81,412,635...81,441,680
Ensembl chr 1:81,413,353...81,441,678
JBrowse link
berylliosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace angiotensin I converting enzyme ISO CTD Direct Evidence: marker/mechanism CTD PMID:10194187 NCBI chr10:94,170,766...94,213,831
Ensembl chr10:94,170,766...94,187,822
JBrowse link
G Btnl2 butyrophilin-like 2 susceptibility ISO DNA:SNP: :rs3117099(human)
CTD Direct Evidence: marker/mechanism
CTD PMID:17927685, PMID:17927685 RGD:9685029 NCBI chr20:4,140,184...4,156,365
Ensembl chr20:4,141,878...4,154,978
JBrowse link
G Ccr5 C-C motif chemokine receptor 5 disease_progression ISO DNA:polymorphisms:5' utr:multiple (human) RGD PMID:20075058 RGD:4892065 NCBI chr 8:133,192,398...133,215,599
Ensembl chr 8:133,197,032...133,215,614
JBrowse link
G Cd28 Cd28 molecule ISO CTD Direct Evidence: marker/mechanism CTD PMID:12952926 NCBI chr 9:67,546,408...67,573,858
Ensembl chr 9:67,546,408...67,571,871
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:16766924 NCBI chr 2:225,827,504...225,847,876
Ensembl chr 2:225,827,504...225,847,874
JBrowse link
G Hmox1 heme oxygenase 1 ISO protein:increased activity:sputum RGD PMID:19453654 RGD:4145349 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Il2ra interleukin 2 receptor subunit alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:8977230 NCBI chr17:70,500,672...70,547,929
Ensembl chr17:70,499,083...70,548,071
JBrowse link
G Il6 interleukin 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:8428540 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G RT1-Db1 RT1 class II, locus Db1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16272364 PMID:17927685 NCBI chr20:4,087,621...4,097,190
Ensembl chr20:4,087,618...4,097,190
JBrowse link
G Tgfb1 transforming growth factor, beta 1 severity ISO DNA:polymorphisms: :-509C>T (human)
CTD Direct Evidence: marker/mechanism
CTD PMID:15750822 PMID:17785866, PMID:17785866 RGD:4145294 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Tnf tumor necrosis factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:8428540 PMID:12449171 PMID:15127972 PMID:16980557 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
Birth Injuries term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccr5 C-C motif chemokine receptor 5 IEP mRNA:increased expression:multiple organs (rat) RGD PMID:18554634 RGD:4890426 NCBI chr 8:133,192,398...133,215,599
Ensembl chr 8:133,197,032...133,215,614
JBrowse link
Blast Injuries term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G App amyloid beta precursor protein IEP RGD PMID:24224042 RGD:10054251 NCBI chr11:24,425,013...24,641,872
Ensembl chr11:24,425,005...24,641,858
JBrowse link
Bone Fractures term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alox5 arachidonate 5-lipoxygenase IMP RGD PMID:19884440 RGD:2317529 NCBI chr 4:148,398,004...148,446,308
Ensembl chr 4:148,398,892...148,446,303
JBrowse link
G Bglap bone gamma-carboxyglutamate protein ISO associated with kidney failure, chronic; RGD PMID:21784896 RGD:7207231 NCBI chr 2:187,741,770...187,748,445
Ensembl chr 2:187,741,770...187,742,747
JBrowse link
G Bmp2 bone morphogenetic protein 2 ISO CTD Direct Evidence: therapeutic CTD PMID:27394662 NCBI chr 3:126,335,963...126,346,771
Ensembl chr 3:126,335,863...126,346,318
JBrowse link
G Bmp7 bone morphogenetic protein 7 ISO CTD Direct Evidence: therapeutic CTD PMID:27394662 NCBI chr 3:170,879,972...170,955,820
Ensembl chr 3:170,879,973...170,955,399
JBrowse link
G Col1a1 collagen type I alpha 1 chain ISO RGD PMID:8432871 RGD:734801 NCBI chr10:82,745,801...82,762,790
Ensembl chr10:82,745,801...82,762,789
JBrowse link
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22504420 NCBI chr 1:248,952,896...248,956,579
Ensembl chr 1:248,895,738...248,898,607
JBrowse link
G Esr1 estrogen receptor 1 no_association ISO DNA:SNP:intron:rs9340799 (human)
DNA:SNP, repeat:promoter:rs2234693 (human)
RGD PMID:15523071, PMID:15523071 RGD:10045827, RGD:10045827 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Fam210a family with sequence similarity 210, member A ISO CTD Direct Evidence: marker/mechanism CTD PMID:22504420 NCBI chr18:64,045,023...64,084,594
Ensembl chr18:64,045,432...64,084,556
JBrowse link
G Fgf2 fibroblast growth factor 2 ISO associated with Diabetes Mellitus, Experimental RGD PMID:8033826 RGD:2315907 NCBI chr 2:124,081,072...124,134,133
Ensembl chr 2:124,081,072...124,134,681
JBrowse link
G Gdf2 growth differentiation factor 2 ISO CTD Direct Evidence: therapeutic CTD PMID:27394662 NCBI chr16:10,267,510...10,293,545
Ensembl chr16:10,267,482...10,273,239
JBrowse link
G Irx5 iroquois homeobox 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22581230 NCBI chr19:16,415,813...16,421,088
Ensembl chr19:16,415,636...16,421,191
JBrowse link
G Lrp5 LDL receptor related protein 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22504420 NCBI chr 1:218,816,833...218,920,147
Ensembl chr 1:218,816,841...218,920,094
JBrowse link
G Mepe matrix extracellular phosphoglycoprotein ISO CTD Direct Evidence: marker/mechanism CTD PMID:22504420 NCBI chr14:6,782,011...6,793,561
Ensembl chr14:6,782,012...6,793,558
JBrowse link
G Pecam1 platelet and endothelial cell adhesion molecule 1 ISO RGD PMID:21788831 RGD:6771211 NCBI chr10:94,850,971...94,913,202 JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 IMP RGD PMID:18795192 RGD:5135218 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Pth parathyroid hormone ISO associated with Renal Insufficiency, Chronic; protein:increased expression:serum (human)
CTD Direct Evidence: therapeutic
CTD PMID:16094769, PMID:23043229 RGD:7242731 NCBI chr 1:178,215,829...178,218,761
Ensembl chr 1:178,215,829...178,218,761
JBrowse link
G Runx1 RUNX family transcription factor 1 IEP RGD PMID:21252473 RGD:11252151 NCBI chr11:32,765,147...33,003,061
Ensembl chr11:32,769,165...33,003,021
JBrowse link
G Runx2 RUNX family transcription factor 2 IEP RGD PMID:21252473 RGD:11252151 NCBI chr 9:18,564,743...18,773,092
Ensembl chr 9:18,564,927...18,773,092
JBrowse link
G Slc25a13 solute carrier family 25 member 13 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22504420 NCBI chr 4:31,134,165...31,757,006
Ensembl chr 4:31,608,269...31,730,386
JBrowse link
G Smad6 SMAD family member 6 IEP RGD PMID:11920662 RGD:724455 NCBI chr 8:68,897,746...68,967,221
Ensembl chr 8:68,898,296...68,966,108
JBrowse link
G Sox9 SRY-box transcription factor 9 IEP RGD PMID:21252473 RGD:11252151 NCBI chr10:101,288,528...101,294,030
Ensembl chr10:101,288,489...101,293,379
JBrowse link
G Sptbn1 spectrin, beta, non-erythrocytic 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22504420 NCBI chr14:114,517,839...114,700,199
Ensembl chr14:114,518,816...114,692,764
JBrowse link
G Tgfbr2 transforming growth factor, beta receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20358619 NCBI chr 8:124,310,288...124,399,345
Ensembl chr 8:124,312,754...124,399,494
JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B ISO CTD Direct Evidence: marker/mechanism CTD PMID:15071724 NCBI chr 5:163,136,390...163,167,299
Ensembl chr 5:163,136,390...163,167,299
JBrowse link
brain compression term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cfl1 cofilin 1 treatment ISO RGD PMID:25708984 RGD:12738361 NCBI chr 1:220,869,805...220,873,337
Ensembl chr 1:220,869,805...220,873,337
JBrowse link
Brain Concussion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Drd2 dopamine receptor D2 IEP RGD PMID:26448536 RGD:13506960 NCBI chr 8:53,678,777...53,743,643
Ensembl chr 8:53,678,777...53,743,642
JBrowse link
G Drd3 dopamine receptor D3 IEP RGD PMID:26448536 RGD:13506960 NCBI chr11:61,819,102...61,883,223
Ensembl chr11:61,822,077...61,874,327
JBrowse link
G Drd4 dopamine receptor D4 IEP RGD PMID:26448536 RGD:13506960 NCBI chr 1:214,278,296...214,282,818
Ensembl chr 1:214,278,296...214,281,483
JBrowse link
G Il6 interleukin 6 treatment IDA RGD PMID:27113205 RGD:11062140 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
Brain Contusion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp3 caspase 3 treatment IEP RGD PMID:28140659 RGD:13782305 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp8 caspase 8 treatment IEP RGD PMID:28140659 RGD:13782305 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
Brain Injuries term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc8 ATP binding cassette subfamily C member 8 treatment IMP RGD PMID:21107131 RGD:12791995 NCBI chr 1:102,110,708...102,191,287
Ensembl chr 1:102,110,708...102,191,287
JBrowse link
G Acan aggrecan IEP mRNA:increased expression:fascia dentata (rat) RGD PMID:18511192 RGD:2315807 NCBI chr 1:140,762,758...140,824,441
Ensembl chr 1:140,762,758...140,824,441
JBrowse link
G Actr2 actin related protein 2 IEP mRNA, protein:decreased expression:hippocampus (rat) RGD PMID:22120305 RGD:11530046 NCBI chr14:104,338,486...104,375,840
Ensembl chr14:104,340,434...104,375,649
JBrowse link
G Adcyap1 adenylate cyclase activating polypeptide 1 IDA RGD PMID:16689670 RGD:2325298 NCBI chr 9:121,705,897...121,725,736
Ensembl chr 9:121,706,979...121,725,716
JBrowse link
G Adra1a adrenoceptor alpha 1A IEP mRNA:increased expression:frontal cortex RGD PMID:20974230 RGD:5688366 NCBI chr15:43,296,997...43,398,314
Ensembl chr15:43,298,794...43,392,451
JBrowse link
G Ager advanced glycosylation end product-specific receptor ISO
IEP
protein:increased expression:brain (rat) RGD PMID:22915134, PMID:24859607, PMID:22491548 RGD:7245513, RGD:8696001, RGD:7245557 NCBI chr20:4,363,152...4,366,079
Ensembl chr20:4,363,152...4,366,079
JBrowse link
G Aif1 allograft inflammatory factor 1 IEP protein:increased expression:cerebral cortex (rat) RGD PMID:19520144 RGD:2313020 NCBI chr20:5,161,350...5,167,176
Ensembl chr20:5,161,333...5,166,448
JBrowse link
G Aifm1 apoptosis inducing factor, mitochondria associated 1 IEP protein:increased expression:nucleus: RGD PMID:12091479 RGD:10053567 NCBI chr  X:135,304,063...135,343,062
Ensembl chr  X:135,304,066...135,343,087
JBrowse link
G Akt1 AKT serine/threonine kinase 1 IEP protein:increased phosphorylation:brain, neuron RGD PMID:16234845 RGD:5509090 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Alb albumin ISO CTD Direct Evidence: marker/mechanism CTD PMID:7909931 PMID:17188501 NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863
JBrowse link
G Ambp alpha-1-microglobulin/bikunin precursor ISO protein:increased expression:urine RGD PMID:14592616 RGD:6904155 NCBI chr 5:78,975,690...78,986,021
Ensembl chr 5:78,975,678...78,985,990
JBrowse link
G Ank3 ankyrin 3 IEP RGD PMID:20557305 RGD:6767288 NCBI chr20:19,948,767...20,480,628
Ensembl chr20:20,105,047...20,480,623
JBrowse link
G Anp32a acidic nuclear phosphoprotein 32 family member A IEP RGD PMID:24385964 RGD:10401136 NCBI chr 8:67,295,578...67,333,075
Ensembl chr 8:67,295,727...67,333,247
JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 IEP protein:increased expression:cerebral cortex RGD PMID:11567033 RGD:2325751 NCBI chr 7:31,699,309...31,784,192
Ensembl chr 7:31,699,885...31,784,192
JBrowse link
G Apbb1 amyloid beta precursor protein binding family B member 1 IEP mRNA:increased expression:brain RGD PMID:12707777 RGD:2301208 NCBI chr 1:170,387,625...170,411,263
Ensembl chr 1:170,387,609...170,404,056
JBrowse link
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11447995 NCBI chr15:27,849,943...27,852,083
Ensembl chr15:27,849,979...27,852,082
JBrowse link
G Apod apolipoprotein D IEP mRNA, protein:increased expression:cerebral cortex, glia cell, neuron RGD PMID:10501208 RGD:2311202 NCBI chr11:72,705,204...72,726,263
Ensembl chr11:72,705,129...72,726,301
JBrowse link
G Apoe apolipoprotein E ISO GAD PMID:15118671 RGD:1331525 NCBI chr 1:80,612,894...80,616,820
Ensembl chr 1:80,612,895...80,617,057
JBrowse link
G App amyloid beta precursor protein ISO protein:increased expression:hippocampus RGD PMID:16300758 RGD:10054281 NCBI chr11:24,425,013...24,641,872
Ensembl chr11:24,425,005...24,641,858
JBrowse link
G Aqp4 aquaporin 4 IEP
ISO
protein:increased expression:cerebral cortex RGD PMID:21083433, PMID:21488209 RGD:5148014, RGD:5148034 NCBI chr18:6,766,009...6,782,757
Ensembl chr18:6,765,945...6,782,996
JBrowse link
G Asic1 acid sensing ion channel subunit 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21307247 NCBI chr 7:141,324,714...141,354,937
Ensembl chr 7:141,326,321...141,354,937
JBrowse link
G Astn1 astrotactin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:14499481 NCBI chr13:76,054,965...76,370,674
Ensembl chr13:76,055,410...76,370,674
JBrowse link
G Atg12 autophagy related 12 IEP protein:altered localization:brain RGD PMID:18059433 RGD:2301217 NCBI chr18:40,721,799...40,732,143
Ensembl chr18:40,721,800...40,732,126
JBrowse link
G Atp5pd ATP synthase peripheral stalk subunit d treatment IDA RGD PMID:26813465 RGD:13800884 NCBI chr10:103,967,340...103,972,552
Ensembl chr10:103,967,312...103,972,668
JBrowse link
G Avpr1a arginine vasopressin receptor 1A IEP mRNA:increased expression:cerebral cortex RGD PMID:17244947 RGD:2300372 NCBI chr 7:67,341,366...67,345,290
Ensembl chr 7:67,341,080...67,345,308
JBrowse link
G Bad BCL2-associated agonist of cell death IEP mRNA, protein:increased expression:cerebral cortex RGD PMID:15941375 RGD:2292694 NCBI chr 1:222,198,516...222,207,459
Ensembl chr 1:222,198,534...222,207,453
JBrowse link
G Bax BCL2 associated X, apoptosis regulator treatment IEP RGD PMID:20888848 RGD:10054247 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcat1 branched chain amino acid transaminase 1 IEP Protein:increased expression:neurons RGD PMID:10686349 RGD:631308 NCBI chr 4:179,259,305...179,340,021
Ensembl chr 4:179,259,308...179,339,795
JBrowse link
G Bcl2 BCL2, apoptosis regulator treatment IMP
IEP
RGD PMID:18093155, PMID:20888848 RGD:2293059, RGD:10054247 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bdnf brain-derived neurotrophic factor IEP
ISO
CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:15500971 PMID:21269288, PMID:20544832 RGD:4891136 NCBI chr 3:100,768,637...100,819,216
Ensembl chr 3:100,768,637...100,819,210
JBrowse link
G Becn1 beclin 1 IEP
ISO
protein:increased expression:neuron, astrocyte
protein:increased expression:hippocampus
protein:increased expression:brain
RGD PMID:18500386, PMID:24221859, PMID:16874043 RGD:6483098, RGD:11558018, RGD:6483314 NCBI chr10:89,209,944...89,225,297
Ensembl chr10:89,209,940...89,225,297
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 IEP mRNA, protein:increased expression:brain, astrocyte, neuron RGD PMID:15453988 RGD:2293136 NCBI chr10:106,856,097...106,864,419
Ensembl chr10:106,856,097...106,864,413
JBrowse link
G Bmp6 bone morphogenetic protein 6 IEP protein:increased expression:brain, astrocyte, neuron RGD PMID:16388909 RGD:2289020 NCBI chr17:26,955,142...27,112,820
Ensembl chr17:26,955,142...27,112,820
JBrowse link
G Bmpr2 bone morphogenetic protein receptor type 2 IEP mRNA:increased expression:dentate gyrus, neuron RGD PMID:9080432 RGD:5129488 NCBI chr 9:66,568,074...66,683,019
Ensembl chr 9:66,568,074...66,676,494
JBrowse link
G Bysl bystin-like IEP mRNA, protein:increased expression:substantia nigra, striatum (rat) RGD PMID:15305856 RGD:2316201 NCBI chr 9:15,393,461...15,403,212
Ensembl chr 9:15,393,330...15,403,117
JBrowse link
G C1qa complement C1q A chain IEP RGD PMID:23808389 RGD:10054313 NCBI chr 5:155,261,254...155,264,101
Ensembl chr 5:155,261,250...155,264,143
JBrowse link
G C3 complement C3 IEP RGD PMID:23808389 RGD:10054313 NCBI chr 9:9,721,137...9,747,084
Ensembl chr 9:9,721,105...9,747,167
JBrowse link
G Cask calcium/calmodulin dependent serine protein kinase IEP RGD PMID:25089700 RGD:11576302 NCBI chr  X:9,815,652...10,156,155
Ensembl chr  X:9,815,652...10,156,155
JBrowse link
G Casp1 caspase 1 IEP mRNA, protein:increased expression:brain RGD PMID:17188500 RGD:2315917 NCBI chr 8:2,605,743...2,614,637
Ensembl chr 8:2,604,962...2,614,631
JBrowse link
G Casp12 caspase 12 severity IEP mRNA, protein:increased expression, increased activity:cerebral cortex, hippocampus, neuron, astrocyte RGD PMID:14675152 RGD:2311485 NCBI chr 8:2,658,892...2,686,160
Ensembl chr 8:2,659,865...2,686,160
JBrowse link
G Casp3 caspase 3 treatment IEP RGD PMID:20888848 RGD:10054247 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp8 caspase 8 IEP protein:altered localization RGD PMID:15590916 RGD:1624191 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Cast calpastatin severity IEP mRNA:increased expression:cerebral cortex RGD PMID:15307896 RGD:5509821 NCBI chr 2:1,452,111...1,561,669
Ensembl chr 2:1,452,116...1,561,464
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 treatment IEP
ISO
IMP
protein:increased expression:brain, neuron
CTD Direct Evidence: marker/mechanism
CTD PMID:21549006, PMID:19210118, PMID:11113322 RGD:2306999, RGD:9587789 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ccl20 C-C motif chemokine ligand 20 treatment IEP RGD PMID:22040257 RGD:7483630 NCBI chr 9:88,918,359...88,921,017
Ensembl chr 9:88,918,433...88,921,001
JBrowse link
G Ccr5 C-C motif chemokine receptor 5 IEP mRNA:increased expression:hippocampus RGD PMID:24344922 RGD:8552265 NCBI chr 8:133,192,398...133,215,599
Ensembl chr 8:133,197,032...133,215,614
JBrowse link
G Cd14 CD14 molecule ISO CTD Direct Evidence: marker/mechanism CTD PMID:21549006 NCBI chr18:29,560,341...29,562,290
Ensembl chr18:29,560,365...29,562,153
JBrowse link
G Cd40 CD40 molecule treatment IDA RGD PMID:23924471 RGD:7248749 NCBI chr 3:161,519,789...161,534,943
Ensembl chr 3:161,519,743...161,534,704
JBrowse link
G Cd40lg CD40 ligand treatment IEP
IDA
RGD PMID:11755016, PMID:25972624 RGD:8547803, RGD:11344972 NCBI chr  X:159,703,703...159,714,886
Ensembl chr  X:159,703,578...159,716,562
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A IEP protein:increased expression:nucleus: RGD PMID:9914434 RGD:8662346 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B IEP protein:decreased expression:cerebral cortex RGD PMID:21728064 RGD:10045359 NCBI chr 4:168,689,043...168,694,159
Ensembl chr 4:168,689,163...168,693,964
JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha ISO mRNA, protein:increased expression:cerebral cortex (mouse) RGD PMID:19833158 RGD:10401206 NCBI chr 1:91,363,492...91,366,164
Ensembl chr 1:91,363,492...91,366,164
JBrowse link
G Cebpb CCAAT/enhancer binding protein beta ISO mRNA, protein:increased expression:cerebral cortex (mouse)
CTD Direct Evidence: marker/mechanism
CTD PMID:21549006, PMID:19833158 RGD:10401206 NCBI chr 3:164,424,502...164,425,933
Ensembl chr 3:164,424,515...164,425,910
JBrowse link
G Ces1d carboxylesterase 1D ISO CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr19:15,195,514...15,239,827
Ensembl chr19:15,033,108...15,239,821
JBrowse link
G Cfb complement factor B ISO CTD Direct Evidence: marker/mechanism CTD PMID:17474994 NCBI chr20:4,536,206...4,542,073
Ensembl chr20:4,536,203...4,561,066
Ensembl chr20:4,536,203...4,561,066
JBrowse link
G Chrm2 cholinergic receptor, muscarinic 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr 4:64,089,028...64,091,090
Ensembl chr 4:64,088,900...64,091,090
JBrowse link
G Chrna7 cholinergic receptor nicotinic alpha 7 subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr 1:123,897,341...124,039,263
Ensembl chr 1:123,899,657...124,039,196
JBrowse link
G Ckmt1 creatine kinase, mitochondrial 1 treatment IEP RGD PMID:24252176 RGD:11565089 NCBI chr 3:113,318,559...113,324,459
Ensembl chr 3:113,318,563...113,324,461
JBrowse link
G Clec4e C-type lectin domain family 4, member E ISO CTD Direct Evidence: marker/mechanism CTD PMID:21549006 NCBI chr 4:156,271,087...156,276,243
Ensembl chr 4:156,270,920...156,276,304
JBrowse link
G Cnp 2',3'-cyclic nucleotide 3' phosphodiesterase IEP protein:increased expression:hippocampus RGD PMID:20215974 RGD:6483336 NCBI chr10:88,490,798...88,497,357
Ensembl chr10:88,490,798...88,497,356
JBrowse link
G Comt catechol-O-methyltransferase IEP protein:increased expression:hippocampus RGD PMID:17240060 RGD:2289740 NCBI chr11:86,715,981...86,735,630
Ensembl chr11:86,715,981...86,735,622
JBrowse link
G Crp C-reactive protein disease_progression ISO RGD PMID:24456846 RGD:9585646 NCBI chr13:91,080,448...91,081,358
Ensembl chr13:91,054,974...91,093,713
JBrowse link
G Csf2 colony stimulating factor 2 disease_progression IDA RGD PMID:21515263 RGD:5686795 NCBI chr10:39,602,089...39,604,070
Ensembl chr10:39,602,089...39,604,070
JBrowse link
G Csf3 colony stimulating factor 3 treatment ISO CTD Direct Evidence: marker/mechanism CTD PMID:21549006, PMID:24239694 RGD:11039431 NCBI chr10:86,616,785...86,619,160
Ensembl chr10:86,616,785...86,619,157
JBrowse link
G Cspg4 chondroitin sulfate proteoglycan 4 IEP protein:altered expression:cerebral cortex RGD PMID:19473238 RGD:5686860 NCBI chr 8:61,532,465...61,567,510
Ensembl chr 8:61,532,465...61,567,510
JBrowse link
G Cul5 cullin 5 IEP mRNA, protein:decreased expression:cerebral cortex, hippocampus RGD PMID:17010517 RGD:2301432 NCBI chr 8:58,199,992...58,255,149
Ensembl chr 8:58,202,821...58,253,688
JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 IEP mRNA:increased expression:choroid plexus, cerebral cortex RGD PMID:19471279 RGD:5135009 NCBI chr14:18,743,678...18,745,457
Ensembl chr14:18,743,685...18,745,457
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21549006 NCBI chr14:17,210,733...17,212,930
Ensembl chr14:17,210,733...17,212,930
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 IEP protein:increased expression:brain, neuron RGD PMID:19210118 RGD:2306999 NCBI chr14:18,731,346...18,733,391
Ensembl chr14:18,731,378...18,733,391
JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 IEP mRNA:increased expression:hindbrain RGD PMID:16329132 RGD:1599699 NCBI chr 8:62,798,317...62,809,848
Ensembl chr 8:62,779,875...62,809,893
JBrowse link
G Cyp4f1 cytochrome P450, family 4, subfamily f, polypeptide 1 IEP RGD PMID:18847377 RGD:2301705 NCBI chr 7:15,179,472...15,191,113
Ensembl chr 7:15,179,467...15,190,796
JBrowse link
G Dab2 DAB adaptor protein 2 IEP RGD PMID:15774263 RGD:7243841 NCBI chr 2:55,747,353...55,768,848
Ensembl chr 2:55,747,318...55,768,270
JBrowse link
G Dnmt1 DNA methyltransferase 1 IEP RGD PMID:19429151 RGD:9588608 NCBI chr 8:21,922,515...21,968,495
Ensembl chr 8:21,922,515...21,968,495
JBrowse link
G Dpysl2 dihydropyrimidinase-like 2 IEP protein:increased degradation:cerebral cortex, hippocampus RGD PMID:17402852 RGD:2303056 NCBI chr15:43,475,640...43,581,725
Ensembl chr15:43,477,629...43,542,939
JBrowse link
G Drd2 dopamine receptor D2 IDA RGD PMID:18509630 RGD:2311580 NCBI chr 8:53,678,777...53,743,643
Ensembl chr 8:53,678,777...53,743,642
JBrowse link
G Dusp5 dual specificity phosphatase 5 IEP mRNA:increased expression:cerebral cortex RGD PMID:12503083 RGD:2317873 NCBI chr 1:274,245,184...274,258,595
Ensembl chr 1:274,245,184...274,258,595
JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha IDA RGD PMID:11526986 RGD:10395358 NCBI chr 6:102,048,372...102,073,041
Ensembl chr 6:102,048,372...102,073,041
JBrowse link
G Eif3e eukaryotic translation initiation factor 3 subunit E treatment IMP RGD PMID:22960363 RGD:10395371 NCBI chr 7:82,997,694...83,037,231 JBrowse link
G Elk1 ETS transcription factor ELK1 IDA RGD PMID:15362724 RGD:7488910 NCBI chr  X:1,287,875...1,304,822
Ensembl chr  X:1,297,099...1,304,822
JBrowse link
G Epas1 endothelial PAS domain protein 1 treatment IDA RGD PMID:22960363 RGD:10395371 NCBI chr 6:10,306,508...10,385,239
Ensembl chr 6:10,306,405...10,387,265
JBrowse link
G Epha4 Eph receptor A4 ISO protein:increased expression, increased activity:astrocyte RGD PMID:22318127 RGD:5688763 NCBI chr 9:83,111,222...83,253,486
Ensembl chr 9:83,111,222...83,253,458
JBrowse link
G Ephx2 epoxide hydrolase 2 ISO RGD PMID:21075124 RGD:5688356 NCBI chr15:42,757,241...42,794,211
Ensembl chr15:42,757,235...42,794,279
JBrowse link
G Epo erythropoietin treatment ISO
IEP
CTD Direct Evidence: therapeutic
mRNA:increased expression:brain:
CTD PMID:20833152, PMID:23063952, PMID:18093155 RGD:10401061, RGD:2293059 NCBI chr12:22,274,828...22,278,268
Ensembl chr12:22,274,828...22,278,266
JBrowse link
G Epor erythropoietin receptor IEP mRNA:increased expression:brain: RGD PMID:18093155 RGD:2293059 NCBI chr 8:22,969,737...22,974,468
Ensembl chr 8:22,969,745...22,974,321
JBrowse link
G F2 coagulation factor II severity ISO RGD PMID:21355766 RGD:5147766 NCBI chr 3:80,529,468...80,542,993
Ensembl chr 3:80,529,428...80,543,031
JBrowse link
G Fas Fas cell surface death receptor IEP
ISO
mRNA:increased expression:hippocampus
associated with Hyperoxia
RGD PMID:16078565, PMID:19107989 RGD:1600354, RGD:8662854 NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790
JBrowse link
G Fgf2 fibroblast growth factor 2 ISO CTD Direct Evidence: therapeutic CTD PMID:21269288 NCBI chr 2:124,081,072...124,134,133
Ensembl chr 2:124,081,072...124,134,681
JBrowse link
G Fmr1 FMRP translational regulator 1 IEP protein:altered localization:hippocampus (rat) RGD PMID:16510718 RGD:11667962 NCBI chr  X:154,684,924...154,722,369
Ensembl chr  X:154,684,935...154,722,314
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:9630518 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Foxp1 forkhead box P1 treatment IDA RGD PMID:26842647 RGD:11561903 NCBI chr 4:131,362,178...131,963,466
Ensembl chr 4:131,366,744...131,694,755
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase IEP protein:decreased expression:hippocampus RGD PMID:18501200 RGD:2307353 NCBI chr  X:156,274,800...156,293,935
Ensembl chr  X:156,274,800...156,293,926
JBrowse link
G Gabrb3 gamma-aminobutyric acid type A receptor subunit beta 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr 1:113,034,251...113,265,364
Ensembl chr 1:112,976,770...113,265,364
JBrowse link
G Gabrg3 gamma-aminobutyric acid type A receptor subunit gamma 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr 1:112,158,525...112,812,267
Ensembl chr 1:112,158,519...112,811,936
JBrowse link
G Gdnf glial cell derived neurotrophic factor IEP mRNA:increased expression:brain RGD PMID:18501516 RGD:2324932 NCBI chr 2:56,884,181...56,912,964
Ensembl chr 2:56,887,987...56,910,238
JBrowse link
G Gja1 gap junction protein, alpha 1 treatment IEP RGD PMID:23485053 RGD:8662424 NCBI chr20:37,876,650...37,889,097
Ensembl chr20:37,876,650...37,889,089
JBrowse link
G Gja5 gap junction protein, alpha 5 IEP protein:increased expression:cerebral artery RGD PMID:21895483 RGD:7207391 NCBI chr 2:199,162,745...199,184,942
Ensembl chr 2:199,162,745...199,184,939
JBrowse link
G Gpx1 glutathione peroxidase 1 IEP mRNA:decreased expression:hippocampus, neuron RGD PMID:15791111 RGD:2306624 NCBI chr 8:117,117,430...117,118,528
Ensembl chr 8:117,117,430...117,118,522
JBrowse link
G Grm8 glutamate metabotropic receptor 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr 4:54,474,344...55,409,526
Ensembl chr 4:54,474,136...55,407,922
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta IEP
ISO
CTD Direct Evidence: marker/mechanism CTD PMID:24675465, PMID:22643085 RGD:10045646 NCBI chr11:65,060,884...65,208,842
Ensembl chr11:65,066,235...65,209,268
JBrowse link
G Gsn gelsolin IEP RGD PMID:14588109 RGD:1599864 NCBI chr 3:14,456,106...14,508,922
Ensembl chr 3:14,467,330...14,508,911
JBrowse link
G Hcn1 hyperpolarization-activated cyclic nucleotide-gated potassium channel 1 IEP mRNA,protein:decreased expression:hippocampus: RGD PMID:11726545 RGD:9686434 NCBI chr 2:50,099,576...50,499,799
Ensembl chr 2:50,099,576...50,499,799
JBrowse link
G Hmgb1 high mobility group box 1 treatment IMP RGD PMID:22915134 RGD:7245513 NCBI chr12:7,082,529...7,090,246
Ensembl chr16:37,500,017...37,502,237
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase IMP RGD PMID:18562561 RGD:5508455 NCBI chr 2:27,480,224...27,500,654
Ensembl chr 2:27,480,226...27,500,654
JBrowse link
G Hmox1 heme oxygenase 1 IEP RGD PMID:23470432 RGD:10755702 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hp haptoglobin IEP mRNA:increased expression:liver RGD PMID:23172820 RGD:11041806 NCBI chr19:42,096,255...42,100,805
Ensembl chr19:42,097,995...42,100,804
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A ISO mRNA:increased expression:brain
CTD Direct Evidence: marker/mechanism
CTD PMID:21549006, PMID:21549006 RGD:5147593 NCBI chr20:4,875,834...4,881,751
Ensembl chr20:4,877,324...4,879,779
JBrowse link
G Hspa4 heat shock protein family A (Hsp70) member 4 IEP protein:increased expression:cerebral white matter (rat) RGD PMID:22067617 RGD:5688785 NCBI chr10:38,601,624...38,642,397
Ensembl chr10:38,601,624...38,642,397
JBrowse link
G Hspb1 heat shock protein family B (small) member 1 IEP RGD PMID:11746764 RGD:6480530 NCBI chr12:23,839,390...23,841,051
Ensembl chr12:23,839,399...23,841,049
JBrowse link
G Htr7 5-hydroxytryptamine receptor 7 IMP RGD PMID:22465320 RGD:6482178 NCBI chr 1:254,547,964...254,671,811
Ensembl chr 1:254,547,620...254,671,778
JBrowse link
G Icam1 intercellular adhesion molecule 1 IEP protein:increased expression:brain: RGD PMID:16230799 RGD:11522716 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
JBrowse link
G Ifnl3 interferon, lambda 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr 1:85,236,243...85,237,775
Ensembl chr 1:85,236,243...85,237,775
JBrowse link
G Igf1 insulin-like growth factor 1 treatment ISO human protein in a rat model RGD PMID:9344566 RGD:12904928 NCBI chr 7:28,412,123...28,491,815
Ensembl chr 7:28,412,198...28,486,609
JBrowse link
G Igf2 insulin-like growth factor 2 IEP mRNA:decreased expression:brain RGD PMID:11123717 RGD:5509972 NCBI chr 1:215,828,102...215,839,081
Ensembl chr 1:215,828,102...215,846,911
JBrowse link
G Il10 interleukin 10 severity
treatment
ISO
IDA
CTD Direct Evidence: marker/mechanism CTD PMID:21549006, PMID:23075771, PMID:23971414 RGD:7364822, RGD:7364983 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G Il12rb2 interleukin 12 receptor subunit beta 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr 4:98,049,195...98,141,562
Ensembl chr 4:98,052,842...98,141,482
JBrowse link
G Il13ra2 interleukin 13 receptor subunit alpha 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr  X:118,443,955...118,514,716
Ensembl chr  X:118,443,823...118,513,061
JBrowse link
G Il16 interleukin 16 IEP RGD PMID:17983426 RGD:5024939 NCBI chr 1:145,781,923...145,881,538
Ensembl chr 1:145,781,928...145,870,912
JBrowse link
G Il17rd interleukin 17 receptor D ISO CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr16:2,670,471...2,737,271
Ensembl chr16:2,670,618...2,731,808
JBrowse link
G Il18 interleukin 18 severity IMP
ISO
mRNA, protein:increased expression:brain RGD PMID:17188500, PMID:17188500 RGD:2315917, RGD:2315917 NCBI chr 8:55,009,666...55,016,286
Ensembl chr 8:54,993,859...55,016,299
JBrowse link
G Il18r1 interleukin 18 receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr 9:47,184,404...47,217,403
Ensembl chr 9:47,185,443...47,219,175
JBrowse link
G Il1a interleukin 1 alpha IEP
ISO
mRNA, protein:increased expression:cerebral cortex
CTD Direct Evidence: marker/mechanism
CTD PMID:21549006, PMID:16024175 RGD:2311098 NCBI chr 3:121,824,712...121,836,122
Ensembl chr 3:121,825,412...121,836,086
JBrowse link
G Il1b interleukin 1 beta IEP
ISO
mRNA, protein:increased expression:cerebral cortex
CTD Direct Evidence: marker/mechanism
protein:increased expression:brain, cerebrospinal fluid
mRNA, protein:increased expression:brain
CTD PMID:19800810 PMID:21549006, PMID:16024175, PMID:22503903, PMID:17612572 RGD:2311098, RGD:6482651, RGD:1626652 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il1r1 interleukin 1 receptor type 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21549006 NCBI chr 9:46,962,291...47,038,139
Ensembl chr 9:46,962,288...47,036,670
JBrowse link
G Il1rn interleukin 1 receptor antagonist ISO CTD Direct Evidence: therapeutic CTD PMID:25665855 NCBI chr 3:1,449,778...1,468,624
Ensembl chr 3:1,452,644...1,468,614
JBrowse link
G Il2 interleukin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr 2:123,847,150...123,851,854
Ensembl chr 2:123,847,150...123,851,854
JBrowse link
G Il3 interleukin 3 disease_progression IDA
ISO
protein: increased expression: brain: microdialysis perfusate RGD PMID:21515263, PMID:20717122 RGD:5686795, RGD:5686886 NCBI chr10:39,620,535...39,622,973
Ensembl chr10:39,620,563...39,622,973
JBrowse link
G Il31ra interleukin 31 receptor A ISO CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr 2:44,333,347...44,408,005
Ensembl chr 2:44,336,006...44,394,709
JBrowse link
G Il4 interleukin 4 IEP protein:decreased expression:plasma RGD PMID:24519543 RGD:10402802 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531
JBrowse link
G Il5 interleukin 5 treatment IEP RGD PMID:24602693, PMID:24530657 RGD:11522766, RGD:11522770 NCBI chr10:39,066,716...39,069,587
Ensembl chr10:39,066,716...39,069,587
JBrowse link
G Il6 interleukin 6 IEP
ISO
protein:increased expression:cerebrospinal fluid (rat)
CTD Direct Evidence: marker/mechanism
CTD PMID:19800810 PMID:21549006 PMID:23159883, PMID:10027774 RGD:11049549 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Il7 interleukin 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr 2:96,427,884...96,474,979
Ensembl chr 2:96,439,286...96,474,977
JBrowse link
G Il9r interleukin 9 receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr10:15,697,216...15,708,684
Ensembl chr10:15,696,824...15,710,423
JBrowse link
G Irf1 interferon regulatory factor 1 IEP
ISO
mRNA:increased expression:cerebral cortex
CTD Direct Evidence: marker/mechanism
CTD PMID:21549006, PMID:12503083 RGD:2317873 NCBI chr10:39,109,530...39,116,532
Ensembl chr10:39,109,522...39,116,531
JBrowse link
G Jak2 Janus kinase 2 IMP RGD PMID:21596098 RGD:6483023 NCBI chr 1:247,398,667...247,457,521
Ensembl chr 1:247,398,598...247,458,509
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:21549006 NCBI chr 5:114,011,184...114,014,277
Ensembl chr 5:114,011,189...114,014,277
JBrowse link
G Kcnj10 potassium inwardly-rectifying channel, subfamily J, member 10 IEP RGD PMID:20861444 RGD:8662901 NCBI chr13:90,722,945...90,753,338
Ensembl chr13:90,723,092...90,752,581
JBrowse link
G Kdr kinase insert domain receptor IEP
IMP
protein:increased expression:cerebral cortex RGD PMID:21307798, PMID:19733172 RGD:5684382, RGD:5684402 NCBI chr14:34,727,677...34,787,127
Ensembl chr14:34,727,623...34,787,183
JBrowse link
G Lep leptin IEP RGD PMID:21276361 RGD:5128517 NCBI chr 4:56,337,695...56,351,818
Ensembl chr 4:56,337,695...56,351,818
JBrowse link
G Lsg1 large 60S subunit nuclear export GTPase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:14499481 NCBI chr11:73,693,862...73,723,457
Ensembl chr11:73,693,814...73,723,501
JBrowse link
G Ly86 lymphocyte antigen 86 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21549006 NCBI chr17:28,104,535...28,191,447
Ensembl chr17:28,104,589...28,191,436
JBrowse link
G Mag myelin-associated glycoprotein susceptibility IMP RGD PMID:17156367 RGD:9685230 NCBI chr 1:89,345,325...89,360,905
Ensembl chr 1:89,345,429...89,360,733
JBrowse link
G Map1b microtubule-associated protein 1B IEP protein:increased expression, increased phosphorylation:brain RGD PMID:10906717 RGD:2304029 NCBI chr 2:29,675,391...29,768,750
Ensembl chr 2:29,675,391...29,768,750
JBrowse link
G Map1lc3a microtubule-associated protein 1 light chain 3 alpha IEP RGD PMID:24221859 RGD:11558018 NCBI chr 3:150,801,289...150,802,935
Ensembl chr 3:150,801,289...150,802,935
JBrowse link
G Map2 microtubule-associated protein 2 IEP
IDA
protein:decreased expression:cerebral cortex, neuron RGD PMID:21401443, PMID:20568963 RGD:6483087, RGD:6483089 NCBI chr 9:73,204,753...73,462,965
Ensembl chr 9:73,319,710...73,462,972
JBrowse link
G Mbl2 mannose binding lectin 2 disease_progression ISO RGD PMID:18183030 RGD:12910935 NCBI chr 1:248,435,069...248,442,669
Ensembl chr 1:248,723,397...248,729,962
JBrowse link
G Mbp myelin basic protein IDA RGD PMID:18583256 RGD:7349333 NCBI chr18:79,326,738...79,437,310
Ensembl chr18:79,326,738...79,437,310
JBrowse link
G Mdm2 MDM2 proto-oncogene IEP protein:increased expression:brain cortex (rat) RGD PMID:15165363 RGD:2317397 NCBI chr 7:60,719,060...60,743,618
Ensembl chr 7:60,719,066...60,743,328
JBrowse link
G Mif macrophage migration inhibitory factor IEP RGD PMID:15922484 RGD:1641989 NCBI chr20:13,715,219...13,732,980
Ensembl chr20:13,732,198...13,732,859
JBrowse link
G Mir132 microRNA 132 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr10:62,014,995...62,015,095
Ensembl chr10:62,014,995...62,015,095
JBrowse link
G Mir144 microRNA 144 IEP RGD PMID:25089700 RGD:11576302 NCBI chr10:65,291,365...65,291,447
Ensembl chr10:65,291,365...65,291,447
JBrowse link
G Mir153 microRNA 153 IEP RGD PMID:25089700 RGD:11576302 NCBI chr 6:145,105,064...145,105,150
Ensembl chr 6:145,105,064...145,105,150
JBrowse link
G Mir183 microRNA 183 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr 4:57,463,569...57,463,678
Ensembl chr 4:57,463,569...57,463,678
JBrowse link
G Mmp9 matrix metallopeptidase 9 treatment IDA
IMP
ISO
CTD Direct Evidence: marker/mechanism CTD PMID:19631748, PMID:16671440, PMID:24661104 RGD:1582656, RGD:13207312 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Mpo myeloperoxidase ISO CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr10:75,087,892...75,098,260
Ensembl chr10:75,087,892...75,098,260
JBrowse link
G Mt-co2 mitochondrially encoded cytochrome c oxidase II IEP mRNA, protein:increased expression:hippocampus RGD PMID:11686499 RGD:2302298 NCBI chr MT:7,006...7,689
Ensembl chr MT:7,006...7,689
JBrowse link
G Mt2A metallothionein 2A ISO
IEP
mRNA:increased expression:liver (mouse)
mRNA:increased expression:dentate gyrus (rat)
RGD PMID:22363575, PMID:15650329 RGD:6483812, RGD:6483847 NCBI chr19:11,307,966...11,308,740
Ensembl chr19:11,307,967...11,308,740
JBrowse link
G Mt3 metallothionein 3 treatment IDA
IEP
RGD PMID:16314047, PMID:10595827, PMID:10218634 RGD:6480628, RGD:9685805, RGD:9685803 NCBI chr19:11,324,708...11,326,112
Ensembl chr19:11,324,698...11,326,139
JBrowse link
G Myoc myocilin IEP mRNA:increased expression:cerebral cortex (rat) RGD PMID:12799138 RGD:7401267 NCBI chr13:80,517,531...80,527,928
Ensembl chr13:80,517,536...80,527,928
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 IEP protein:increased expression:lung: RGD PMID:18787991, PMID:25089700 RGD:5134971, RGD:11576302 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Ngb neuroglobin severity IEP RGD PMID:21915648 RGD:9743963 NCBI chr 6:111,126,259...111,131,699
Ensembl chr 6:111,126,261...111,132,320
JBrowse link
G Ngfr nerve growth factor receptor treatment IDA RGD PMID:23940017 RGD:10414074 NCBI chr10:83,389,828...83,408,061
Ensembl chr10:83,389,847...83,408,061
JBrowse link
G Nos2 nitric oxide synthase 2 IEP RGD PMID:11526986 RGD:10395358 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Nppb natriuretic peptide B ISO associated with lung diseases;protein:increased expression:serum:
CTD Direct Evidence: therapeutic
CTD PMID:19803787, PMID:23837838 RGD:7247620 NCBI chr 5:164,796,176...164,797,538
Ensembl chr 5:164,796,185...164,797,531
JBrowse link
G Npy neuropeptide Y IEP protein:increased expression:adrenal medulla RGD PMID:23570732 RGD:10448961 NCBI chr 4:79,557,856...79,565,059
Ensembl chr 4:79,557,854...79,565,097
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 treatment IEP mRNA:increased expression:lung
associated with Subarachnoid Hemorrhage
RGD PMID:18787991, PMID:20864352 RGD:5134971, RGD:11035222 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Nt5e 5' nucleotidase, ecto IEP protein:altered expression:cerebral cortex (rat) RGD PMID:21337375 RGD:5134348 NCBI chr 8:95,969,002...96,012,733
Ensembl chr 8:95,968,652...96,012,696
JBrowse link
G P2ry1 purinergic receptor P2Y1 IEP protein:increased expression:brain, astrocyte RGD PMID:19115395 RGD:2315811 NCBI chr 2:151,314,818...151,320,312
Ensembl chr 2:151,314,818...151,320,319
JBrowse link
G Palld palladin, cytoskeletal associated protein IEP protein:increased expression:brain, astrocyte RGD PMID:12932445 RGD:2325786 NCBI chr16:31,865,712...31,948,168 JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17640816 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Pawr pro-apoptotic WT1 regulator IEP mRNA,protein:increased expression:brain: RGD PMID:11421591 RGD:9835358 NCBI chr 7:51,273,764...51,353,700
Ensembl chr 7:51,273,771...51,353,068
JBrowse link
G Pde4d phosphodiesterase 4D IEP mRNA, protein:alternative form, decreased phosphorylation:brain RGD PMID:23057870 RGD:7327147 NCBI chr 2:40,219,999...41,468,551
Ensembl chr 2:40,554,146...41,464,264
JBrowse link
G Pdgfa platelet derived growth factor subunit A IEP mRNA:increased expression:cerebral cortex, hippocampus RGD PMID:9645955 RGD:11084932 NCBI chr12:17,734,141...17,756,186
Ensembl chr12:17,734,133...17,755,285
JBrowse link
G Pdgfb platelet derived growth factor subunit B IEP mRNA:increased expression:cerebral cortex, hippocampus RGD PMID:9645955 RGD:11084932 NCBI chr 7:121,215,458...121,233,092
Ensembl chr 7:121,214,628...121,232,741
JBrowse link
G Pdgfra platelet derived growth factor receptor alpha IEP mRNA:increased expression:cerebral cortex, hippocampus RGD PMID:9645955 RGD:11084932 NCBI chr14:35,527,926...35,581,130
Ensembl chr14:35,527,927...35,581,031
JBrowse link
G Pdgfrb platelet derived growth factor receptor beta IEP mRNA:increased expression:cerebral cortex, hippocampus RGD PMID:9645955 RGD:11084932 NCBI chr18:56,364,586...56,406,381
Ensembl chr18:56,364,620...56,406,381
JBrowse link
G Pecam1 platelet and endothelial cell adhesion molecule 1 IDA RGD PMID:22658532 RGD:6484732 NCBI chr10:94,850,971...94,913,202 JBrowse link
G Pglyrp1 peptidoglycan recognition protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21549006 NCBI chr 1:79,790,879...79,796,064
Ensembl chr 1:79,790,705...79,796,111
JBrowse link
G Pgr progesterone receptor IEP RGD PMID:23211561 RGD:7248711 NCBI chr 8:7,128,656...7,187,796
Ensembl chr 8:7,128,656...7,187,796
JBrowse link
G Phb prohibitin IEP protein:increased oxidation:cerebral cortex RGD PMID:17518533 RGD:2292409 NCBI chr10:83,476,107...83,488,878
Ensembl chr10:83,476,107...83,488,878
JBrowse link
G Phb2 prohibitin 2 IEP RGD PMID:24566151 RGD:12903261 NCBI chr 4:157,230,769...157,235,375
Ensembl chr 4:157,230,769...157,235,367
JBrowse link
G Pias1 protein inhibitor of activated STAT, 1 IEP protein:decreased expression:brain, nucleus RGD PMID:21545521 RGD:8693413 NCBI chr 8:67,771,720...67,869,015
Ensembl chr 8:67,771,720...67,869,019
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha IDA agonist more effective in combination with simvastatin RGD PMID:18562561 RGD:5508455 NCBI chr 7:126,618,872...126,687,282
Ensembl chr 7:126,619,196...126,681,752
JBrowse link
G Ppargc1a PPARG coactivator 1 alpha treatment ISO
IEP
protein:decreased expression:frontal cortex (rat) RGD PMID:22642418, PMID:24345766 RGD:6484257, RGD:10059630 NCBI chr14:63,095,291...63,190,688
Ensembl chr14:63,095,720...63,187,009
JBrowse link
G Ppp3ca protein phosphatase 3 catalytic subunit alpha IEP
ISO
protein: :hippocampus
CTD Direct Evidence: marker/mechanism
CTD PMID:14499481, PMID:19751097 RGD:6483311 NCBI chr 2:241,909,332...242,186,861
Ensembl chr 2:241,909,832...242,184,854
JBrowse link
G Prf1 perforin 1 ISO RGD PMID:20537642 RGD:6482807 NCBI chr20:30,915,294...30,920,804
Ensembl chr20:30,915,213...30,921,382
JBrowse link
G Ptger3 prostaglandin E receptor 3 IEP protein:increased expression:striatum, microglia (rat) RGD PMID:15234107 RGD:9850280 NCBI chr 2:263,895,093...263,979,682
Ensembl chr 2:263,895,241...263,979,698
JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 ISO
IEP
protein:increased expression:microglia, macrophage
protein:increased expression:microglial cells, macrophage, endothelial cell
RGD PMID:19719848, PMID:11565600, PMID:12005397 RGD:5688162, RGD:5688242, RGD:5688239 NCBI chr 3:15,560,685...15,582,339
Ensembl chr 3:15,560,712...15,582,344
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 IMP
ISO
CTD Direct Evidence: marker/mechanism CTD PMID:12410334 PMID:20810888 PMID:21549006, PMID:21866634, PMID:19719848 RGD:5508191, RGD:5688162 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Ptprz1 protein tyrosine phosphatase, receptor type Z1 IEP RGD PMID:12088737 RGD:727637 NCBI chr 4:49,941,046...50,140,764
Ensembl chr 4:49,941,304...50,140,762
JBrowse link
G Rchy1 ring finger and CHY zinc finger domain containing 1 IEP protein:increased expression:cerebral cortex RGD PMID:21728064 RGD:10045359 NCBI chr14:17,615,968...17,631,715
Ensembl chr14:17,615,968...17,631,714
JBrowse link
G Reg3b regenerating family member 3 beta IEP mRNA:increased expression:cerebral cortex (rat) RGD PMID:19351265 RGD:9831399 NCBI chr 4:109,467,272...109,470,510
Ensembl chr 4:109,467,272...109,470,510
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit IEP protein:increased expression:ileum RGD PMID:18288455 RGD:2298787 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Ret ret proto-oncogene IEP mRNA:increased expression:brain RGD PMID:18501516 RGD:2324932 NCBI chr 4:150,202,170...150,249,196
Ensembl chr 4:150,202,058...150,244,372
JBrowse link
G Rhoa ras homolog family member A IEP protein:increased expression:microglial cell, brain RGD PMID:17929039 RGD:2298888 NCBI chr 8:117,082,440...117,116,244
Ensembl chr 8:117,106,576...117,116,167
JBrowse link
G Robo1 roundabout guidance receptor 1 IEP mRNA:increased expression:brain RGD PMID:16262652 RGD:2316136 NCBI chr11:9,079,291...10,146,302
Ensembl chr11:9,642,365...10,143,317
JBrowse link
G Robo2 roundabout guidance receptor 2 IEP mRNA:increased expression:brain RGD PMID:16262652 RGD:2316136 NCBI chr11:11,062,866...12,618,793
Ensembl chr11:11,062,790...11,585,765
JBrowse link
G Robo3 roundabout guidance receptor 3 IEP mRNA:increased expression:brain RGD PMID:16262652 RGD:2316136 NCBI chr 8:39,892,792...39,923,735
Ensembl chr 8:39,892,792...39,907,478
JBrowse link
G Rps27a ribosomal protein S27a IEP mRNA:decreased expression:cerebral cortex, hippocampus RGD PMID:17936732 RGD:11041870 NCBI chr14:113,966,163...113,968,440
Ensembl chr14:113,966,611...113,968,268
Ensembl chr 5:113,966,611...113,968,268
JBrowse link
G S100b S100 calcium binding protein B severity ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:11520488 PMID:21783483, PMID:21976236 RGD:5508761 NCBI chr20:13,130,633...13,142,856
Ensembl chr20:13,130,636...13,142,856
JBrowse link
G Sele selectin E IEP protein:increased expression:brain RGD PMID:19107536 RGD:2313599 NCBI chr13:82,355,234...82,365,323
Ensembl chr13:82,355,471...82,365,341
JBrowse link
G Serpinc1 serpin family C member 1 ISO CTD Direct Evidence: therapeutic CTD PMID:21534203 NCBI chr13:78,806,107...78,820,375
Ensembl chr13:78,805,347...78,833,192
JBrowse link
G Serpinf1 serpin family F member 1 treatment ISO
IEP
human gene in a rat model
protein:altered expression:cerebellum (rat)
RGD PMID:20142768, PMID:17709187 RGD:8612994, RGD:8622925 NCBI chr10:62,241,750...62,254,145
Ensembl chr10:62,241,756...62,254,287
JBrowse link
G Sirt1 sirtuin 1 treatment IEP RGD PMID:17970622 RGD:9497541 NCBI chr20:26,831,971...26,851,587
Ensembl chr20:26,833,357...26,852,199
JBrowse link
G Skp2 S-phase kinase associated protein 2 IEP protein:increased expression:brain RGD PMID:19852587 RGD:2315049 NCBI chr 2:58,506,146...58,534,211
Ensembl chr 2:58,506,151...58,534,211
JBrowse link
G Slc18a3 solute carrier family 18 member A3 IEP protein:decreased expression:brain RGD PMID:18848922 RGD:5686682 NCBI chr16:8,682,668...8,685,529
Ensembl chr16:8,682,669...8,685,529
JBrowse link
G Slit1 slit guidance ligand 1 IEP mRNA:increased expression:brain RGD PMID:16262652 RGD:2316136 NCBI chr 1:260,843,481...260,992,366
Ensembl chr 1:260,843,483...260,992,366
JBrowse link
G Slit3 slit guidance ligand 3 IEP mRNA:increased expression:brain RGD PMID:16262652 RGD:2316136 NCBI chr10:19,924,200...20,517,918
Ensembl chr10:20,320,878...20,518,518
JBrowse link
G Snca synuclein alpha ISO
IEP
RGD PMID:14637093, PMID:25089700 RGD:6480195, RGD:11576302 NCBI chr 4:90,782,412...90,883,236
Ensembl chr 4:90,782,374...90,882,285
JBrowse link
G Sncb synuclein, beta ISO RGD PMID:14637093 RGD:6480195 NCBI chr17:10,384,472...10,392,776
Ensembl chr17:10,384,511...10,392,843
JBrowse link
G Sncg synuclein, gamma ISO RGD PMID:14637093 RGD:6480195 NCBI chr16:10,722,110...10,726,648
Ensembl chr16:10,722,106...10,726,707
JBrowse link
G Snw1 SNW domain containing 1 IEP mRNA, protein:increased expression:cerebral cortex (rat) RGD PMID:22965216 RGD:11035237 NCBI chr 6:111,483,698...111,507,782
Ensembl chr 6:111,483,703...111,507,782
JBrowse link
G Sod1 superoxide dismutase 1 ISO RGD PMID:16248885 RGD:1581214 NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862
JBrowse link
G Sod2 superoxide dismutase 2 ISO CTD Direct Evidence: therapeutic CTD PMID:24462953, PMID:16248885 RGD:1581214 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
JBrowse link
G Sparc secreted protein acidic and cysteine rich IEP mRNA:increased expression:brain, blood vessel RGD PMID:9704602 RGD:2300066 NCBI chr10:40,742,390...40,764,232
Ensembl chr10:40,742,400...40,764,185
JBrowse link
G Sstr2 somatostatin receptor 2 IEP RGD PMID:11879809 RGD:2325002 NCBI chr10:102,136,283...102,143,449
Ensembl chr10:102,136,283...102,143,434
JBrowse link
G Sstr3 somatostatin receptor 3 IEP RGD PMID:11879809 RGD:2325002 NCBI chr 7:119,760,881...119,768,082
Ensembl chr 7:119,760,888...119,768,082
JBrowse link
G Sstr4 somatostatin receptor 4 IEP RGD PMID:11879809 RGD:2325002 NCBI chr 3:142,739,781...142,741,644
Ensembl chr 3:142,739,781...142,741,644
JBrowse link
G Stat1 signal transducer and activator of transcription 1 IMP RGD PMID:21596098 RGD:6483023 NCBI chr 9:54,287,540...54,327,958
Ensembl chr 9:54,287,541...54,484,533
JBrowse link
G Stat3 signal transducer and activator of transcription 3 IMP
IDA
protein:increased phosphorylation:brain RGD PMID:21596098, PMID:22145815, PMID:22827467 RGD:6483023, RGD:8694312, RGD:6892706 NCBI chr10:88,790,401...88,842,263
Ensembl chr10:88,790,408...88,842,233
JBrowse link
G Strn striatin IEP RGD PMID:16351572 RGD:2311293 NCBI chr 6:1,232,729...1,319,603
Ensembl chr 6:1,237,758...1,319,541
JBrowse link
G Tardbp TAR DNA binding protein ISO RGD PMID:22101322 RGD:5687195 NCBI chr 5:165,432,089...165,442,232
Ensembl chr 5:165,432,095...165,442,048
JBrowse link
G Tf transferrin IEP RGD PMID:22538758 RGD:7244386 NCBI chr 8:111,694,570...111,721,275
Ensembl chr 8:111,673,547...111,721,333
JBrowse link
G Th tyrosine hydroxylase IEP protein:decreased activity:striatum (rat) RGD PMID:21047500 RGD:5128822 NCBI chr 1:216,073,034...216,080,287
Ensembl chr 1:216,073,031...216,080,287
JBrowse link
G Thbd thrombomodulin onset ISO RGD PMID:17895610 RGD:5685007 NCBI chr 3:142,748,673...142,752,325
Ensembl chr 3:142,748,674...142,752,325
JBrowse link
G Ticam2 toll-like receptor adaptor molecule 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21549006 NCBI chr18:40,555,106...40,572,569
Ensembl chr18:40,555,106...40,572,241
JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 IEP mRNA:increased expression:brain, astrocytes RGD PMID:10719361 RGD:2290468 NCBI chr  X:1,364,771...1,369,451
Ensembl chr  X:1,364,786...1,369,384
JBrowse link
G Timp2 TIMP metallopeptidase inhibitor 2 IEP mRNA:increased expression:brain, neuron, microglial cell RGD PMID:10719361 RGD:2290468 NCBI chr10:107,338,465...107,386,072
Ensembl chr10:107,338,465...107,386,072
JBrowse link
G Tjp1 tight junction protein 1 IEP RGD PMID:19889224 RGD:2325128 NCBI chr 1:126,146,489...126,515,359
Ensembl chr 1:126,146,489...126,227,469
JBrowse link
G Tlr1 toll-like receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21549006 NCBI chr14:45,062,662...45,065,014
Ensembl chr14:45,062,662...45,081,991
JBrowse link
G Tlr2 toll-like receptor 2 IEP
ISO
mRNA:increased expression:brain
CTD Direct Evidence: marker/mechanism
CTD PMID:21549006, PMID:18316784 RGD:2312713 NCBI chr 2:182,840,171...182,846,061
Ensembl chr 2:182,840,727...182,846,061
JBrowse link
G Tlr4 toll-like receptor 4 IEP
ISO
mRNA:increased expression:brain
CTD Direct Evidence: marker/mechanism
CTD PMID:21549006, PMID:18316784 RGD:2312713 NCBI chr 5:82,587,424...82,601,056
Ensembl chr 5:82,587,420...82,601,052
JBrowse link
G Tlr9 toll-like receptor 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21549006 NCBI chr 8:114,916,122...114,920,171
Ensembl chr 8:114,916,122...114,920,171
JBrowse link
G Tnf tumor necrosis factor ISO
IMP
CTD Direct Evidence: marker/mechanism CTD PMID:19800810 PMID:21549006, PMID:10674461 RGD:13825262 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tnfrsf13b TNF receptor superfamily member 13B ISO CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr10:47,399,834...47,422,907
Ensembl chr10:47,412,582...47,420,951
JBrowse link
G Tnfrsf13c TNF receptor superfamily member 13C ISO CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr 7:123,453,799...123,456,289
Ensembl chr 7:123,453,788...123,456,268
JBrowse link
G Tnfrsf14 TNF receptor superfamily member 14 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr 5:172,328,259...172,337,221
Ensembl chr 5:172,328,262...172,335,892
JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A IEP
ISO
protein:increased expression:brain
CTD Direct Evidence: marker/mechanism
CTD PMID:21549006, PMID:17074049 RGD:1624183 NCBI chr 4:157,864,905...157,877,634
Ensembl chr 4:157,864,969...157,877,633
JBrowse link
G Tnfsf10 TNF superfamily member 10 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr 2:113,008,008...113,026,899
Ensembl chr 2:113,007,549...113,026,899
JBrowse link
G Tnfsf12 TNF superfamily member 12 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr10:56,290,780...56,300,137
Ensembl chr10:56,290,780...56,300,077
JBrowse link
G Traf4 Tnf receptor associated factor 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr10:65,418,688...65,424,802
Ensembl chr10:65,418,700...65,424,802
JBrowse link
G Trpm2 transient receptor potential cation channel, subfamily M, member 2 IEP mRNA, protein:increased expression:cerebral cortex, hippocampus RGD PMID:20309649 RGD:9999437 NCBI chr20:11,434,062...11,482,880
Ensembl chr20:11,436,267...11,482,051
JBrowse link
G Uba52 ubiquitin A-52 residue ribosomal protein fusion product 1 IEP mRNA:decreased expression:cerebral cortex, hippocampus (rat) RGD PMID:17936732 RGD:11041870 NCBI chr16:20,668,925...20,671,127
Ensembl chr16:20,668,971...20,671,127
JBrowse link
G Ucp2 uncoupling protein 2 ISO CTD Direct Evidence: therapeutic CTD PMID:12858170, PMID:12858170 RGD:7204436 NCBI chr 1:165,506,375...165,512,744
Ensembl chr 1:165,506,361...165,512,744
JBrowse link
G Vegfa vascular endothelial growth factor A IEP
ISO
CTD Direct Evidence: therapeutic CTD PMID:18065154, PMID:12230324 RGD:1580574 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681
JBrowse link
G Vegfb vascular endothelial growth factor B IEP mRNA, protein:increased expression:brain RGD PMID:12230324 RGD:1580574 NCBI chr 1:222,237,000...222,242,786
Ensembl chr 1:222,239,022...222,242,644
JBrowse link
G Vim vimentin ISO
IEP
protein:increased expression:brain RGD PMID:19728994, PMID:15527750 RGD:6480519, RGD:6480527 NCBI chr17:80,882,715...80,891,200
Ensembl chr17:80,882,666...80,891,212
JBrowse link
G Xdh xanthine dehydrogenase treatment IEP RGD PMID:26528358 RGD:13208950 NCBI chr 6:25,149,570...25,211,273
Ensembl chr 6:25,149,235...25,211,494
JBrowse link
Brain Injuries, Diffuse term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G S100b S100 calcium binding protein B ISO CTD Direct Evidence: marker/mechanism CTD PMID:30076900 NCBI chr20:13,130,633...13,142,856
Ensembl chr20:13,130,636...13,142,856
JBrowse link
Brain Injuries, Traumatic term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adam10 ADAM metallopeptidase domain 10 IEP RGD PMID:22489706 RGD:13703033 NCBI chr 8:77,107,355...77,237,483
Ensembl chr 8:77,107,536...77,237,483
JBrowse link
G App amyloid beta precursor protein treatment ISO RGD PMID:29320530 RGD:13782048 NCBI chr11:24,425,013...24,641,872
Ensembl chr11:24,425,005...24,641,858
JBrowse link
G Bad BCL2-associated agonist of cell death treatment IEP RGD PMID:24582457 RGD:13782254 NCBI chr 1:222,198,516...222,207,459
Ensembl chr 1:222,198,534...222,207,453
JBrowse link
G Capn1 calpain 1 IEP protein:increased expression:cytosol, plasma membrane RGD PMID:9469158 RGD:13792664 NCBI chr 1:221,346,081...221,370,965
Ensembl chr 1:221,346,066...221,370,322
JBrowse link
G Capn2 calpain 2 IEP RGD PMID:9469158 RGD:13792664 NCBI chr13:100,878,649...100,928,811
Ensembl chr13:100,878,650...100,928,811
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 treatment ISO RGD PMID:26435412 RGD:27095897 NCBI chr14:17,210,733...17,212,930
Ensembl chr14:17,210,733...17,212,930
JBrowse link
G Drd1 dopamine receptor D1 treatment IEP RGD PMID:24047867 RGD:13506948 NCBI chr17:11,099,736...11,104,352
Ensembl chr17:11,101,306...11,103,541
JBrowse link
G Drd2 dopamine receptor D2 treatment IEP RGD PMID:24047867 RGD:13506948 NCBI chr 8:53,678,777...53,743,643
Ensembl chr 8:53,678,777...53,743,642
JBrowse link
G Fubp1 far upstream element binding protein 1 IEP RGD PMID:23797733 RGD:13673879 NCBI chr 2:257,425,676...257,452,745
Ensembl chr 2:257,425,679...257,449,568
JBrowse link
G Gnal G protein subunit alpha L IEP RGD PMID:29215295 RGD:13513923 NCBI chr18:62,805,406...62,946,133
Ensembl chr18:62,805,410...62,944,630
JBrowse link
G Icam1 intercellular adhesion molecule 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28642177 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
JBrowse link
G Il1b interleukin 1 beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:28642177 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Itgb1 integrin subunit beta 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25668593 NCBI chr19:61,677,512...61,725,537
Ensembl chr19:61,677,542...61,725,535
JBrowse link
G Lama1 laminin subunit alpha 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25668593 NCBI chr 9:115,916,907...116,042,123
Ensembl chr 9:115,916,907...116,042,123
JBrowse link
G Lamp2 lysosomal-associated membrane protein 2 IEP protein:increased expression:hippocampus: RGD PMID:28365875 RGD:13703062 NCBI chr  X:124,722,628...124,766,079
Ensembl chr  X:124,722,628...124,766,044
JBrowse link
G Mapt microtubule-associated protein tau treatment IDA
IEP
RGD PMID:28412141, PMID:25771151, PMID:26484783, PMID:26729399 RGD:13800902, RGD:13800917, RGD:13800912, RGD:13800909 NCBI chr10:92,289,002...92,386,517
Ensembl chr10:92,288,910...92,386,517
JBrowse link
G Mir155 microRNA 155 ISO RGD PMID:28804446 RGD:25314324 NCBI chr11:24,176,603...24,176,667
Ensembl chr11:24,176,603...24,176,667
JBrowse link
G Mmp9 matrix metallopeptidase 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25668593 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Mpo myeloperoxidase ISO CTD Direct Evidence: marker/mechanism CTD PMID:25668593 NCBI chr10:75,087,892...75,098,260
Ensembl chr10:75,087,892...75,098,260
JBrowse link
G Ncstn nicastrin ISO RGD PMID:18240300 RGD:13801189 NCBI chr13:90,451,046...90,467,256
Ensembl chr13:90,451,044...90,467,256
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 IEP protein:increased expression:brain: RGD PMID:30855558 RGD:26884463 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Nmnat1 nicotinamide nucleotide adenylyltransferase 1 ISO CTD Direct Evidence: therapeutic CTD PMID:27822499 NCBI chr 5:166,409,460...166,430,291
Ensembl chr 5:166,409,461...166,430,254
JBrowse link
G Nos2 nitric oxide synthase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28642177 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Ocln occludin ISO CTD Direct Evidence: marker/mechanism CTD PMID:25668593 NCBI chr 2:30,527,327...30,577,218
Ensembl chr 2:30,527,715...30,577,218
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15829224 PMID:28642177 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Pde10a phosphodiesterase 10A IEP RGD PMID:29215295 RGD:13513923 NCBI chr 1:52,360,296...52,544,448
Ensembl chr 1:52,360,296...52,544,450
JBrowse link
G Ppp3r1 protein phosphatase 3, regulatory subunit B, alpha IEP RGD PMID:20713027 RGD:13830881 NCBI chr14:100,311,224...100,360,879
Ensembl chr14:100,311,173...100,360,879
JBrowse link
G Ppp3r2 protein phosphatase 3, regulatory subunit B, beta IEP RGD PMID:20713027 RGD:13830881 NCBI chr 5:64,945,583...64,946,578
Ensembl chr 5:64,945,583...64,946,580
JBrowse link
G Psen1 presenilin 1 ISO RGD PMID:18240300 RGD:13801189 NCBI chr 6:107,169,514...107,221,000
Ensembl chr 6:107,169,528...107,216,798
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28642177 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:25668593 PMID:28642177 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Tgfb1 transforming growth factor, beta 1 treatment IEP RGD PMID:28433746 RGD:14995478 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Tnf tumor necrosis factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:28642177 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tp53 tumor protein p53 treatment IMP RGD PMID:27553877 RGD:14995939 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Ube4b ubiquitination factor E4B ISO CTD Direct Evidence: therapeutic CTD PMID:27822499 NCBI chr 5:166,156,033...166,259,069
Ensembl chr 5:166,156,033...166,259,069
JBrowse link
Bronchopulmonary Dysplasia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2 associated X, apoptosis regulator IEP RGD PMID:26431790 RGD:11537057 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bid BH3 interacting domain death agonist IEP RGD PMID:26431790 RGD:11537057 NCBI chr 4:153,439,812...153,465,247
Ensembl chr 4:153,442,218...153,465,203
JBrowse link
G Casp3 caspase 3 IEP RGD PMID:26431790 RGD:11537057 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp8 caspase 8 IEP RGD PMID:26431790 RGD:11537057 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Casp9 caspase 9 IEP RGD PMID:26431790 RGD:11537057 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Cat catalase IDA RGD PMID:19693467 RGD:5130750 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Ccl7 C-C motif chemokine ligand 7 ISO RGD PMID:16888287 RGD:5130981 NCBI chr10:69,423,083...69,424,933
Ensembl chr10:69,423,086...69,424,979
JBrowse link
G Cd209 CD209 molecule ISO RGD PMID:20050784 RGD:5131185 NCBI chr12:2,406,879...2,413,324
Ensembl chr12:2,406,879...2,413,324
JBrowse link
G Cd209c CD209c molecule ISO RGD PMID:20050784 RGD:5131185 NCBI chr12:2,837,991...2,846,709
Ensembl chr12:2,838,128...2,843,772
JBrowse link
G Chi3l1 chitinase 3 like 1 ISO protein:decreased secretion:lung, secretion (human) RGD PMID:20558631 RGD:4892651 NCBI chr13:51,022,844...51,030,797
Ensembl chr13:51,022,681...51,030,802
JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 IEP RGD PMID:19951473 RGD:5134972 NCBI chr14:18,743,678...18,745,457
Ensembl chr14:18,743,685...18,745,457
JBrowse link
G Dag1 dystroglycan 1 ISO DNA:SNP: :p.N494H (human) RGD PMID:17196572 RGD:11537474 NCBI chr 8:116,980,501...116,993,182
Ensembl chr 8:116,980,497...116,993,193
JBrowse link
G Edn1 endothelin 1 IEP protein:increased expression:lung (rat) RGD PMID:20647310 RGD:4144841 NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324
JBrowse link
G Epas1 endothelial PAS domain protein 1 treatment IEP RGD PMID:23065129 RGD:10395385 NCBI chr 6:10,306,508...10,385,239
Ensembl chr 6:10,306,405...10,387,265
JBrowse link
G Flt1 Fms related receptor tyrosine kinase 1 ISO RGD PMID:22003089 RGD:10402122 NCBI chr12:9,033,993...9,205,886
Ensembl chr12:9,034,308...9,205,905
JBrowse link
G Gstm1 glutathione S-transferase mu 1 susceptibility ISO DNA:deletion, haplotype:: (human) RGD PMID:24120392 RGD:12792215 NCBI chr 2:210,803,869...210,809,461
Ensembl chr 2:210,803,869...210,809,306
JBrowse link
G Gstp1 glutathione S-transferase pi 1 susceptibility ISO DNA:polymorphism:exon:p.I105V (human) RGD PMID:14726935 RGD:4142520 NCBI chr 1:219,291,679...219,294,147
Ensembl chr 1:219,291,679...219,294,147
JBrowse link
G Gstt1 glutathione S-transferase theta 1 susceptibility ISO DNA:deletion, haplotype:: (human) RGD PMID:24120392 RGD:12792215 NCBI chr20:13,799,102...13,816,527
Ensembl chr20:13,799,102...13,816,526
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha treatment IEP RGD PMID:23065129, PMID:26431790 RGD:10395385, RGD:11537057 NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052
JBrowse link
G Il1b interleukin 1 beta ISO protein:increased expression:lung
CTD Direct Evidence: marker/mechanism
CTD PMID:16813970, PMID:15539764 RGD:4143172 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il1rn interleukin 1 receptor antagonist susceptibility ISO protein:increased expression:lung
associated with Premature Birth;DNA:polymorphism::
RGD PMID:15539764, PMID:22882323 RGD:4143172, RGD:12910846 NCBI chr 3:1,449,778...1,468,624
Ensembl chr 3:1,452,644...1,468,614
JBrowse link
G Mbl2 mannose binding lectin 2 susceptibility ISO associated with Premature Birth;DNA:polymorphism:exon: RGD PMID:22882323 RGD:12910846 NCBI chr 1:248,435,069...248,442,669
Ensembl chr 1:248,723,397...248,729,962
JBrowse link
G Mif macrophage migration inhibitory factor ISO associated with Respiratory Distress Syndrome, Newborn; protein:increased expression:lung RGD PMID:18097062 RGD:4891007 NCBI chr20:13,715,219...13,732,980
Ensembl chr20:13,732,198...13,732,859
JBrowse link
G Mmp9 matrix metallopeptidase 9 ISO RGD PMID:19097983 RGD:5129685 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Muc1 mucin 1, cell surface associated severity ISO protein:increased expression:cord plasma RGD PMID:18025794 RGD:5131170 NCBI chr 2:188,543,137...188,547,874
Ensembl chr 2:188,543,137...188,547,874
JBrowse link
G Postn periostin ISO CTD Direct Evidence: marker/mechanism CTD PMID:22363622 NCBI chr 2:143,656,820...143,688,087
Ensembl chr 2:143,656,793...143,688,087
JBrowse link
G Scgb1a1 secretoglobin family 1A member 1 ISO RGD PMID:11435254 RGD:5144211 NCBI chr 1:225,279,698...225,283,246
Ensembl chr 1:225,279,676...225,283,326
JBrowse link
G Serpine1 serpin family E member 1 ISO associated with Premature Birth;protein:increased expression:blood: RGD PMID:25140773 RGD:13208551 NCBI chr12:22,641,104...22,651,482
Ensembl chr12:22,641,104...22,651,482
JBrowse link
G Sftpa1 surfactant protein A1 susceptibility ISO DNA:snps, haplotypes:multiple (human)
DNA:polymorphisms, haplotype: (human)
RGD PMID:17264398, PMID:11105614 RGD:4143384, RGD:4144876 NCBI chr16:18,716,019...18,719,404
Ensembl chr16:18,716,019...18,719,403
JBrowse link
G Sftpb surfactant protein B susceptibility ISO DNA:deletion:intron (human)
DNA:polymorphism:intron (human)
RGD PMID:15102713, PMID:17264398, PMID:12424586 RGD:4143405, RGD:4143384, RGD:4143418 NCBI chr 4:100,166,855...100,175,941
Ensembl chr 4:100,166,863...100,175,938
JBrowse link
G Sftpd surfactant protein D ISO RGD PMID:17264398 RGD:4143384 NCBI chr16:18,753,535...18,766,100
Ensembl chr16:18,745,458...18,766,174
JBrowse link
G Tnf tumor necrosis factor severity
no_association
ISO DNA:SNP:promoter:-238A>G (human)
DNA:SNP:promoter:-308G>A (human)
RGD PMID:15286263, PMID:15286263 RGD:12904049, RGD:12904049 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tp53 tumor protein p53 IEP RGD PMID:26431790 RGD:11537057 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Txn1 thioredoxin 1 ISO CTD Direct Evidence: therapeutic CTD PMID:20812253 NCBI chr 5:75,049,735...75,057,731
Ensembl chr 5:75,049,747...75,057,752
JBrowse link
G Vdr vitamin D receptor susceptibility ISO associated with Premature Birth;DNA:SNPs: :rs2228570,rs731236(human) RGD PMID:24796371 RGD:13432055 NCBI chr 7:139,344,452...139,394,138
Ensembl chr 7:139,342,063...139,394,166
JBrowse link
Burns term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A2m alpha-2-macroglobulin IEP RGD PMID:14960360 RGD:1598513 NCBI chr 4:154,309,426...154,359,138
Ensembl chr 4:154,309,426...154,359,137
JBrowse link
G Alb albumin disease_progression ISO RGD PMID:23917657 RGD:11036092 NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863
JBrowse link
G Bad BCL2-associated agonist of cell death IEP protein:increased expression:neutrophil RGD PMID:15625305 RGD:2292697 NCBI chr 1:222,198,516...222,207,459
Ensembl chr 1:222,198,534...222,207,453
JBrowse link
G Bax BCL2 associated X, apoptosis regulator treatment IEP RGD PMID:22153006 RGD:10054126 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcl2 BCL2, apoptosis regulator treatment IEP RGD PMID:22153006 RGD:10054126 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Becn1 beclin 1 IEP RGD PMID:24730400 RGD:11561936 NCBI chr10:89,209,944...89,225,297
Ensembl chr10:89,209,940...89,225,297
JBrowse link
G Casp3 caspase 3 treatment IEP RGD PMID:22153006 RGD:10054126 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Ccnc cyclin C IEP protein:increased expression:skin RGD PMID:16271231 RGD:2315993 NCBI chr 5:35,865,598...35,883,732
Ensembl chr 5:35,865,605...35,883,706
JBrowse link
G Ccnd1 cyclin D1 IEP RGD PMID:17996899 RGD:2289134 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Cd14 CD14 molecule IEP mRNA:increased expression:multiple organs: RGD PMID:11829837, PMID:12435950 RGD:7204443, RGD:2313390 NCBI chr18:29,560,341...29,562,290
Ensembl chr18:29,560,365...29,562,153
JBrowse link
G Cd86 CD86 molecule IEP protein:increased expression:spleen, dendritic cell (rat) RGD PMID:20233162 RGD:4892209 NCBI chr11:67,060,305...67,117,990
Ensembl chr11:67,082,193...67,118,795
JBrowse link
G Cldn1 claudin 1 IEP associated with Binge Drinking;protein: decreased tyrosine phosphorylation:intestine mucosa" RGD PMID:22001439 RGD:8655996 NCBI chr11:77,815,216...77,830,373
Ensembl chr11:77,815,181...77,830,416
JBrowse link
G Cpb2 carboxypeptidase B2 IDA protein:increased activity:plasma RGD PMID:15497025 RGD:2313648 NCBI chr15:57,290,849...57,339,762
Ensembl chr15:57,290,849...57,339,760
JBrowse link
G Crp C-reactive protein IEP RGD PMID:20664819 RGD:5131457 NCBI chr13:91,080,448...91,081,358
Ensembl chr13:91,054,974...91,093,713
JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 IEP protein:increased expression:serum RGD PMID:18391855 RGD:5135231 NCBI chr14:18,743,678...18,745,457
Ensembl chr14:18,743,685...18,745,457
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 IEP protein:increased expression:serum RGD PMID:18391855 RGD:5135231 NCBI chr14:18,731,346...18,733,391
Ensembl chr14:18,731,378...18,733,391
JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 IEP protein:increased expression:serum RGD PMID:18391855 RGD:5135231 NCBI chr14:18,820,168...18,839,659
Ensembl chr14:18,820,168...18,839,595
JBrowse link
G Eef1a1 eukaryotic translation elongation factor 1 alpha 1 IEP protein:decreased expression:heart,mitochondrion: RGD PMID:23041468 RGD:10401126 NCBI chr 8:85,838,594...85,841,816
Ensembl chr 8:85,838,869...85,840,818
JBrowse link
G Fga fibrinogen alpha chain IEP protein:increased expression:plasma (rat) RGD PMID:20664819 RGD:5131457 NCBI chr 2:181,997,562...182,013,726
Ensembl chr 2:182,006,242...182,013,763
JBrowse link
G Fgfr1 Fibroblast growth factor receptor 1 IEP protein:increased expression:epidermis: RGD PMID:9204964 RGD:10402083 NCBI chr16:71,265,390...71,319,046
Ensembl chr16:71,266,248...71,319,449
JBrowse link
G Fyn FYN proto-oncogene, Src family tyrosine kinase IEP protein:decreased phosphorylation, decreased activity:T cell (rat) RGD PMID:12353920 RGD:2324864 NCBI chr20:44,436,354...44,630,316
Ensembl chr20:44,436,403...44,630,317
JBrowse link
G Grk2 G protein-coupled receptor kinase 2 IEP mRNA:increased expression:heart left ventricle (rat) RGD PMID:29232706 RGD:13506829 NCBI chr 1:219,536,220...219,544,329
Ensembl chr 1:219,536,220...219,544,328
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta IEP protein:increased activity,altered phosphorylation:skeletal muscle: RGD PMID:17686886 RGD:10045647 NCBI chr11:65,060,884...65,208,842
Ensembl chr11:65,066,235...65,209,268
JBrowse link
G Gsta4 glutathione S-transferase alpha 4 ISO mRNA:altered expression:fat, muscle, skin (human)
mRNA:decreased expression:gastrocnemius muscle (mouse)
RGD PMID:22038048, PMID:22038048 RGD:5687774, RGD:5687774 NCBI chr 8:85,497,557...85,514,732
Ensembl chr 8:85,497,557...85,518,879
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha IEP protein:increased expression:Peyer's patches (rat) RGD PMID:19439119 RGD:9068477 NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052
JBrowse link
G Hmgb1 high mobility group box 1 treatment IEP RGD PMID:20723408 RGD:10402183 NCBI chr12:7,082,529...7,090,246
Ensembl chr16:37,500,017...37,502,237
JBrowse link
G Igf1 insulin-like growth factor 1 IEP mRNA:altered expression:multiple RGD PMID:10827012 RGD:12910869 NCBI chr 7:28,412,123...28,491,815
Ensembl chr 7:28,412,198...28,486,609
JBrowse link
G Igf1r insulin-like growth factor 1 receptor IEP protein:decreased expression:skeletal muscle: RGD PMID:25186839 RGD:10046020 NCBI chr 1:128,924,921...129,213,816
Ensembl chr 1:128,924,966...129,206,516
JBrowse link
G Igfals insulin-like growth factor binding protein, acid labile subunit IEP mRNA:decreased expression:liver RGD PMID:10827012 RGD:12910869 NCBI chr10:14,240,308...14,243,554
Ensembl chr10:14,240,219...14,243,597
JBrowse link
G Igfbp1 insulin-like growth factor binding protein 1 IEP mRNA:increased expression:kidney, liver RGD PMID:10827012 RGD:12910869 NCBI chr14:87,448,716...87,453,783
Ensembl chr14:87,448,692...87,453,785
JBrowse link
G Igfbp3 insulin-like growth factor binding protein 3 IEP mRNA:altered expression:kidney, liver, muscle RGD PMID:10827012 RGD:12910869 NCBI chr14:87,457,647...87,465,374
Ensembl chr14:87,457,647...87,465,374
JBrowse link
G Igfbp7 insulin-like growth factor binding protein 7 IEP mRNA:increased expression:liver RGD PMID:11742840 RGD:1626551 NCBI chr14:33,010,300...33,070,193
Ensembl chr14:33,010,300...33,070,190
JBrowse link
G Il10 interleukin 10 treatment IEP
ISO
CTD Direct Evidence: marker/mechanism CTD PMID:18277951, PMID:22341647 RGD:11049470 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G Il18 interleukin 18 ISO protein:decreased expression:liver RGD PMID:19197224 RGD:4889576 NCBI chr 8:55,009,666...55,016,286
Ensembl chr 8:54,993,859...55,016,299
JBrowse link
G Il1a interleukin 1 alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:10431976 NCBI chr 3:121,824,712...121,836,122
Ensembl chr 3:121,825,412...121,836,086
JBrowse link
G Il1b interleukin 1 beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:18277951 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il6 interleukin 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:10431976 PMID:18277951 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Lbp lipopolysaccharide binding protein IEP RGD PMID:12435950 RGD:2313390 NCBI chr 3:154,786,232...154,812,910
Ensembl chr 3:154,786,215...154,813,464
JBrowse link
G Map1lc3a microtubule-associated protein 1 light chain 3 alpha IEP RGD PMID:24730400 RGD:11561936 NCBI chr 3:150,801,289...150,802,935
Ensembl chr 3:150,801,289...150,802,935
JBrowse link
G Mif macrophage migration inhibitory factor IEP mRNA, protein:increased expression:liver, serum RGD PMID:14625478 RGD:1642001 NCBI chr20:13,715,219...13,732,980
Ensembl chr20:13,732,198...13,732,859
JBrowse link
G Mmp7 matrix metallopeptidase 7 IEP mRNA:increased expression:ileum RGD PMID:15182445 RGD:9685358 NCBI chr 8:5,893,253...5,900,965
Ensembl chr 8:5,893,249...5,901,049
JBrowse link
G Mmp9 matrix metallopeptidase 9 IEP mRNA, protein:increased expression:brain RGD PMID:17156757 RGD:1642051 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Mpo myeloperoxidase IEP
ISO
protein:increased activity:kidney, lung
CTD Direct Evidence: marker/mechanism
CTD PMID:11996850, PMID:22356815 RGD:6909170 NCBI chr10:75,087,892...75,098,260
Ensembl chr10:75,087,892...75,098,260
JBrowse link
G Mstn myostatin IEP mRNA:increased expression:skeletal muscle RGD PMID:11481237 RGD:2303598 NCBI chr 9:53,310,977...53,315,804
Ensembl chr 9:53,309,598...53,315,915
JBrowse link
G Mt-cyb mitochondrially encoded cytochrome b IDA RGD PMID:3779466 RGD:2298976 NCBI chr MT:14,136...15,278
Ensembl chr MT:14,136...15,278
JBrowse link
G Mtor mechanistic target of rapamycin kinase IDA protein:increased serine phosphorylation:skeletal muscle RGD PMID:20594757 RGD:10041043 NCBI chr 5:165,263,813...165,373,967
Ensembl chr 5:165,263,800...165,373,967
JBrowse link
G Ncf2 neutrophil cytosolic factor 2 IEP protein:increased expression:neutrophil RGD PMID:9329126 RGD:2314453 NCBI chr13:70,226,441...70,259,019
Ensembl chr13:70,226,647...70,257,576
JBrowse link
G Ngf nerve growth factor IMP RGD PMID:12133564 RGD:5144074 NCBI chr 2:204,886,158...204,939,523
Ensembl chr 2:204,886,202...204,940,453
JBrowse link
G Nos2 nitric oxide synthase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15650120 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 treatment IDA
IEP
protein:decreased activity:liver, lung, kidney RGD PMID:19216853, PMID:11990926 RGD:4892319, RGD:7174720 NCBI chr18:31,728,373...32,704,022
Ensembl chr18:31,728,373...31,749,647
JBrowse link
G Ocln occludin IEP associated with Binge Drinking;protein:decreased expression, decreased tyrosine, threonine phosphorylation:intestine mucosa: RGD PMID:22001439 RGD:8655996 NCBI chr 2:30,527,327...30,577,218
Ensembl chr 2:30,527,715...30,577,218
JBrowse link
G Oxct1 3-oxoacid CoA transferase 1 IEP protein:increased expression:ileum (rat) RGD PMID:15449568 RGD:2326198 NCBI chr 2:53,859,738...54,007,733
Ensembl chr 2:53,859,737...54,007,756
JBrowse link
G Oxt oxytocin/neurophysin I prepropeptide IMP RGD PMID:17826914 RGD:2304127 NCBI chr 3:123,106,694...123,107,534
Ensembl chr 3:123,106,694...123,107,534
JBrowse link
G Pdcd1 programmed cell death 1 treatment ISO associated with Pseudomonas Infections; associated with Staphylococcal Infections RGD PMID:29345058 RGD:41410788 NCBI chr 9:101,305,742...101,319,937
Ensembl chr 9:101,307,764...101,319,845
Ensembl chr 9:101,307,764...101,319,845
JBrowse link
G Pde4b phosphodiesterase 4B IEP mRNA:increased expression:extensor digitorum longus muscle RGD PMID:29693432 RGD:13782127 NCBI chr 5:121,759,236...122,136,814
Ensembl chr 5:121,952,977...122,136,814
JBrowse link
G Pklr pyruvate kinase L/R IDA RGD PMID:12417155 RGD:1625591 NCBI chr 2:188,449,158...188,458,034
Ensembl chr 2:188,449,210...188,459,592
JBrowse link
G Pla2g4a phospholipase A2 group IVA IEP protein:increased expression:heart RGD PMID:17483741 RGD:1642444 NCBI chr13:67,062,252...67,206,688
Ensembl chr13:66,988,937...67,206,693
JBrowse link
G Plat plasminogen activator, tissue type ISO protein:increased expression:plasma (human) RGD PMID:11525850 RGD:11541048 NCBI chr16:74,098,263...74,122,897
Ensembl chr16:74,098,260...74,122,889
JBrowse link
G Pomc proopiomelanocortin ISO CTD Direct Evidence: marker/mechanism CTD PMID:2968671 NCBI chr 6:28,382,937...28,388,771
Ensembl chr 6:28,382,962...28,388,967
JBrowse link
G Prkcd protein kinase C, delta IEP protein:altered localization:cardiac muscle cell RGD PMID:16990486 RGD:1642547 NCBI chr16:6,655,131...6,675,746
Ensembl chr16:6,655,120...6,675,746
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15650120 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Rapgef3 Rap guanine nucleotide exchange factor 3 treatment IDA RGD PMID:24973766 RGD:9850087 NCBI chr 7:139,232,263...139,254,668
Ensembl chr 7:139,232,251...139,254,551
JBrowse link
G Rapgef4 Rap guanine nucleotide exchange factor 4 treatment IDA RGD PMID:24973766 RGD:9850087 NCBI chr 3:58,632,338...58,925,127
Ensembl chr 3:58,632,476...58,924,038
JBrowse link
G Rps6kb1 ribosomal protein S6 kinase B1 IEP protein:decreased phosphorylation:heart RGD PMID:14695116 RGD:1643025 NCBI chr10:73,824,200...73,865,503
Ensembl chr10:73,824,202...73,865,364
JBrowse link
G Serpina1 serpin family A member 1 IEP protein:increased expression:serum RGD PMID:12509927 RGD:1643164 NCBI chr 6:127,610,241...127,632,265
Ensembl chr 6:127,610,243...127,632,265
JBrowse link
G Serping1 serpin family G member 1 treatment ISO RGD PMID:22447201 RGD:6903314 NCBI chr 3:72,161,230...72,171,109
Ensembl chr 3:72,161,189...72,171,078
JBrowse link
G Slc6a4 solute carrier family 6 member 4 IEP RGD PMID:17711618 RGD:4889516 NCBI chr10:63,153,656...63,188,377
Ensembl chr10:63,153,651...63,176,463
JBrowse link
G Socs3 suppressor of cytokine signaling 3 IEP mRNA, protein:increased expression:hepatocyte RGD PMID:12392283 RGD:730264 NCBI chr10:106,973,863...106,976,969
Ensembl chr10:106,975,178...106,976,040
JBrowse link
G Tac1 tachykinin, precursor 1 ISO protein:increased expression:plasma, lung RGD PMID:19797759 RGD:5147812 NCBI chr 4:33,638,853...33,646,819
Ensembl chr 4:33,638,709...33,646,819
JBrowse link
G Tacr1 tachykinin receptor 1 ISO mRNA:increased expression:lung RGD PMID:18523300 RGD:5147819 NCBI chr 4:113,247,236...113,416,139
Ensembl chr 4:113,247,795...113,414,504
JBrowse link
G Tfpi tissue factor pathway inhibitor IEP protein:decreased activity:plasma: RGD PMID:15497025 RGD:2313648 NCBI chr 3:71,852,738...71,902,127
Ensembl chr 3:71,852,744...71,893,618
JBrowse link
G Tnf tumor necrosis factor treatment IDA
ISO
CTD Direct Evidence: marker/mechanism CTD PMID:18277951, PMID:26152211 RGD:11049530 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tnfrsf10b TNF receptor superfamily member 10b IEP mRNA, protein:increased expression:thymus RGD PMID:18019056 RGD:2290498 NCBI chr15:51,433,853...51,464,215 JBrowse link
G Ucn urocortin IEP RGD PMID:16125201 RGD:1642782 NCBI chr 6:26,602,144...26,602,974
Ensembl chr 6:26,602,144...26,602,974
JBrowse link
G Vdac2 voltage-dependent anion channel 2 IEP RGD PMID:23863682 RGD:10003047 NCBI chr15:2,634,622...2,648,548
Ensembl chr15:2,634,624...2,648,551
JBrowse link
Burns, Chemical term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alox12 arachidonate 12-lipoxygenase, 12S type ISO CTD Direct Evidence: marker/mechanism CTD PMID:22533443 NCBI chr10:56,851,734...56,864,049
Ensembl chr10:56,851,734...56,864,005
JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22533443 NCBI chr 1:200,590,951...200,696,946
Ensembl chr 1:200,590,953...200,696,928
JBrowse link
G Il1a interleukin 1 alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:22533443 NCBI chr 3:121,824,712...121,836,122
Ensembl chr 3:121,825,412...121,836,086
JBrowse link
G Il1b interleukin 1 beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:22533443 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il1r1 interleukin 1 receptor type 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22533443 NCBI chr 9:46,962,291...47,038,139
Ensembl chr 9:46,962,288...47,036,670
JBrowse link
G Il6 interleukin 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22533443 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
Cardiotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bche butyrylcholinesterase ISO CTD Direct Evidence: therapeutic CTD PMID:26145887 NCBI chr 2:171,104,476...171,196,186
Ensembl chr 2:171,100,140...171,196,395
JBrowse link
G Bmp2 bone morphogenetic protein 2 ISO CTD Direct Evidence: therapeutic CTD PMID:29800642 NCBI chr 3:126,335,963...126,346,771
Ensembl chr 3:126,335,863...126,346,318
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29959987 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Csf1 colony stimulating factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:32068018 NCBI chr 2:210,522,370...210,550,546
Ensembl chr 2:210,522,375...210,550,560
JBrowse link
G Hbegf heparin-binding EGF-like growth factor ISO CTD Direct Evidence: therapeutic CTD PMID:29305325 NCBI chr18:29,330,302...29,340,185
Ensembl chr18:29,329,764...29,340,403
JBrowse link
G Il1b interleukin 1 beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:32068018 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Mir208a microRNA 208a ISO CTD Direct Evidence: marker/mechanism CTD PMID:26454886 NCBI chr15:33,613,451...33,613,533 JBrowse link
G Nos3 nitric oxide synthase 3 treatment ISO associated with Precursor Cell Lymphoblastic Leukemia-Lymphoma;DNA:polymorphism: :894G>T(human) RGD PMID:26345518 RGD:11533645 NCBI chr 4:7,321,908...7,342,404
Ensembl chr 4:7,320,668...7,342,410