RGD Reference Report - Repair of chronic tympanic membrane perforations using epidermal growth factor. - Rat Genome Database

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Repair of chronic tympanic membrane perforations using epidermal growth factor.

Authors: Amoils, CP  Jackler, RK  Lustig, LR 
Citation: Amoils CP, etal., Otolaryngol Head Neck Surg. 1992 Nov;107(5):669-83.
RGD ID: 11556276
Pubmed: (View Article at PubMed) PMID:1437205

Perforation of the tympanic membrane (TM) is a frequent cause of conductive hearing loss. Persistent TM perforations often require surgical repair with an autologous tissue graft to restore hearing and prevent recurrent infection. While highly efficacious, this method of closure requires a relatively complex and expensive microsurgical procedure. We have recently developed a chronic TM perforation model in the chinchilla for use in the exploration of novel methods of TM repair.

Annotation

Disease Annotations    

Objects Annotated

Genes (Homo sapiens)
EGF  (epidermal growth factor)

Genes (Chinchilla lanigera)
Egf  (epidermal growth factor)


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