17beta-estradiol increases expression ISO RGD:1354369 6480464 Estradiol results in increased expression of HEY2 mRNA CTD PMID:21185374 , PMID:31614463 17beta-estradiol multiple interactions ISO RGD:1354369 6480464 Raloxifene Hydrochloride inhibits the reaction [Estradiol results in increased expression of HEY2 mRNA] CTD PMID:21185374 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:1553745 6480464 Tetrachlorodibenzodioxin affects the expression of HEY2 mRNA CTD PMID:24058054 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of HEY2 mRNA CTD PMID:27913140 more ... 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:1354369 6480464 Tetrachlorodibenzodioxin results in decreased expression of HEY2 mRNA CTD PMID:27913140 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:1553745 6480464 Tetrachlorodibenzodioxin results in increased expression of HEY2 mRNA CTD PMID:27913140 3,3',5,5'-tetrabromobisphenol A multiple interactions EXP 6480464 N-(N-(3, 5-difluorophenacetyl)alanyl)phenylglycine tert-butyl ester inhibits the reaction [tetrabromobisphenol A results in increased expression of HEY2 mRNA] CTD PMID:32041402 3,3',5,5'-tetrabromobisphenol A increases expression EXP 6480464 tetrabromobisphenol A results in increased expression of HEY2 mRNA CTD PMID:32041402 3,4-methylenedioxymethamphetamine decreases expression ISO RGD:1553745 6480464 N-Methyl-3, 4-methylenedioxyamphetamine results in decreased expression of HEY2 mRNA CTD PMID:26251327 4,4'-sulfonyldiphenol increases expression ISO RGD:1553745 6480464 bis(4-hydroxyphenyl)sulfone results in increased expression of HEY2 mRNA CTD PMID:30951980 5-aza-2'-deoxycytidine affects expression ISO RGD:1354369 6480464 Decitabine affects the expression of HEY2 mRNA CTD PMID:23300844 6-propyl-2-thiouracil increases expression EXP 6480464 Propylthiouracil results in increased expression of HEY2 mRNA CTD PMID:24780913 8-Br-cAMP decreases expression ISO RGD:1354369 6480464 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of HEY2 mRNA CTD PMID:22079614 acrylamide decreases expression EXP 6480464 Acrylamide results in decreased expression of HEY2 mRNA CTD PMID:28959563 acrylamide decreases expression ISO RGD:1354369 6480464 Acrylamide results in decreased expression of HEY2 mRNA CTD PMID:32763439 aflatoxin B1 decreases methylation ISO RGD:1354369 6480464 Aflatoxin B1 results in decreased methylation of HEY2 gene CTD PMID:27153756 all-trans-retinoic acid increases expression ISO RGD:1354369 6480464 Tretinoin results in increased expression of HEY2 mRNA CTD PMID:21934132 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of HEY2 mRNA CTD PMID:16483693 antirheumatic drug increases expression ISO RGD:1354369 6480464 Antirheumatic Agents results in increased expression of HEY2 mRNA CTD PMID:24449571 arsane decreases expression ISO RGD:1553745 6480464 Arsenic results in decreased expression of HEY2 mRNA CTD PMID:24019935 arsenic atom decreases expression ISO RGD:1553745 6480464 Arsenic results in decreased expression of HEY2 mRNA CTD PMID:24019935 arsenous acid decreases expression ISO RGD:1354369 6480464 Arsenic Trioxide results in decreased expression of HEY2 mRNA CTD PMID:26705709 baicalein multiple interactions ISO RGD:1354369 6480464 N-(N-(3, 5-difluorophenacetyl)alanyl)phenylglycine tert-butyl ester inhibits the reaction [baicalein results in increased expression of HEY2 mRNA] CTD PMID:19160421 baicalein increases expression ISO RGD:1354369 6480464 baicalein results in increased expression of HEY2 mRNA CTD PMID:19160421 baicalin multiple interactions ISO RGD:1354369 6480464 N-(N-(3, 5-difluorophenacetyl)alanyl)phenylglycine tert-butyl ester inhibits the reaction [baicalin results in increased expression of HEY2 mRNA] CTD PMID:19160421 baicalin increases expression ISO RGD:1354369 6480464 baicalin results in increased expression of HEY2 mRNA CTD PMID:19160421 belinostat multiple interactions ISO RGD:1354369 6480464 [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of HEY2 mRNA CTD PMID:27188386 belinostat increases expression ISO RGD:1354369 6480464 belinostat results in increased expression of HEY2 mRNA CTD PMID:26272509 benzo[a]pyrene multiple interactions ISO RGD:1553745 6480464 Benzo(a)pyrene promotes the reaction [AHR protein binds to HEY2 promoter] CTD PMID:19654925 benzo[a]pyrene affects methylation ISO RGD:1354369 6480464 Benzo(a)pyrene affects the methylation of HEY2 promoter CTD PMID:27901495 benzo[a]pyrene increases expression ISO RGD:1553745 6480464 Benzo(a)pyrene results in increased expression of HEY2 mRNA CTD PMID:22228805 bis(2-chloroethyl) sulfide increases expression ISO RGD:1553745 6480464 Mustard Gas results in increased expression of HEY2 mRNA CTD PMID:15674844 bis(2-ethylhexyl) phthalate decreases expression ISO RGD:1553745 6480464 Diethylhexyl Phthalate results in decreased expression of HEY2 mRNA, Diethylhexyl Phthalate results in decreased expression of HEY2 protein CTD PMID:29377175 bisphenol A affects expression EXP 6480464 bisphenol A affects the expression of HEY2 mRNA CTD PMID:25181051 bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of HEY2 mRNA CTD PMID:30816183 more ... bisphenol A affects methylation ISO RGD:1553745 6480464 bisphenol A affects the methylation of HEY2 promoter CTD PMID:27334623 capsaicin increases expression EXP 6480464 Capsaicin results in increased expression of HEY2 mRNA CTD PMID:16278290 carbon nanotube increases expression ISO RGD:1354369 6480464 Nanotubes, Carbon results in increased expression of HEY2 mRNA CTD PMID:25511174 CGP 52608 multiple interactions ISO RGD:1354369 6480464 CGP 52608 promotes the reaction [RORA protein binds to HEY2 gene] CTD PMID:28238834 choline multiple interactions ISO RGD:1553745 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of HEY2 gene CTD PMID:20938992 cisplatin affects expression ISO RGD:1354369 6480464 Cisplatin affects the expression of HEY2 mRNA CTD PMID:23300844 cisplatin multiple interactions ISO RGD:1553745 6480464 [Cisplatin co-treated with RELB mutant form co-treated with TNF protein] results in increased expression of HEY2 mRNA CTD PMID:23625948 Cuprizon increases expression EXP 6480464 Cuprizone results in increased expression of HEY2 mRNA CTD PMID:27523638 DAPT multiple interactions ISO RGD:1354369 6480464 N-(N-(3 more ... CTD PMID:19160421 DAPT multiple interactions EXP 6480464 N-(N-(3, 5-difluorophenacetyl)alanyl)phenylglycine tert-butyl ester inhibits the reaction [tetrabromobisphenol A results in increased expression of HEY2 mRNA] CTD PMID:32041402 diallyl trisulfide decreases expression ISO RGD:1354369 6480464 diallyl trisulfide results in decreased expression of HEY2 mRNA CTD PMID:23430952 diarsenic trioxide decreases expression ISO RGD:1354369 6480464 Arsenic Trioxide results in decreased expression of HEY2 mRNA CTD PMID:26705709 dioxygen increases expression ISO RGD:1354369 6480464 Oxygen deficiency results in increased expression of HEY2 mRNA CTD PMID:24236059 dorsomorphin multiple interactions ISO RGD:1354369 6480464 [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 doxorubicin decreases expression ISO RGD:1354369 6480464 Doxorubicin results in decreased expression of HEY2 mRNA CTD PMID:29803840 doxorubicin increases expression ISO RGD:1553745 6480464 Doxorubicin results in increased expression of HEY2 mRNA CTD PMID:28318631 doxorubicin multiple interactions ISO RGD:1553745 6480464 Niclosamide inhibits the reaction [Doxorubicin results in increased expression of HEY2 mRNA] CTD PMID:28318631 endosulfan decreases expression EXP 6480464 Endosulfan results in decreased expression of HEY2 mRNA CTD PMID:29391264 entinostat multiple interactions ISO RGD:1354369 6480464 [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of HEY2 mRNA CTD PMID:27188386 entinostat increases expression ISO RGD:1354369 6480464 entinostat results in increased expression of HEY2 mRNA CTD PMID:26272509 folic acid multiple interactions ISO RGD:1553745 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of HEY2 gene CTD PMID:20938992 L-methionine multiple interactions ISO RGD:1553745 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of HEY2 gene CTD PMID:20938992 lead diacetate increases expression ISO RGD:1553745 6480464 lead acetate results in increased expression of HEY2 mRNA CTD PMID:22609695 lipopolysaccharide decreases expression ISO RGD:1354369 6480464 Lipopolysaccharides results in decreased expression of HEY2 mRNA CTD PMID:35811015 lipopolysaccharide multiple interactions ISO RGD:1354369 6480464 [S-(1 more ... CTD PMID:35811015 maneb multiple interactions ISO RGD:1553745 6480464 [LRRK2 protein mutant form co-treated with Maneb co-treated with Paraquat] results in decreased expression of HEY2 mRNA, [Maneb co-treated with Paraquat] results in decreased expression of HEY2 mRNA CTD PMID:23017109 , PMID:36117858 methylisothiazolinone increases expression ISO RGD:1354369 6480464 2-methyl-4-isothiazolin-3-one results in increased expression of HEY2 mRNA CTD PMID:31629900 methylmercury chloride decreases expression ISO RGD:1354369 6480464 methylmercuric chloride results in decreased expression of HEY2 mRNA CTD PMID:28001369 nickel atom decreases expression ISO RGD:1354369 6480464 Nickel results in decreased expression of HEY2 mRNA CTD PMID:24768652 , PMID:25583101 niclosamide multiple interactions EXP 6480464 Niclosamide inhibits the reaction [TGFB1 protein results in increased expression of HEY2 mRNA] CTD PMID:28318631 niclosamide multiple interactions ISO RGD:1354369 6480464 N-(N-(3, 5-difluorophenacetyl)alanyl)phenylglycine tert-butyl ester inhibits the reaction [Niclosamide results in increased expression of HEY2 mRNA] CTD PMID:19160421 niclosamide multiple interactions ISO RGD:1553745 6480464 Niclosamide inhibits the reaction [Doxorubicin results in increased expression of HEY2 mRNA] CTD PMID:28318631 niclosamide increases expression ISO RGD:1354369 6480464 Niclosamide results in increased expression of HEY2 mRNA CTD PMID:19160421 oxaliplatin multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in increased expression of HEY2 mRNA CTD PMID:25729387 panobinostat multiple interactions ISO RGD:1354369 6480464 [NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of HEY2 mRNA CTD PMID:27188386 panobinostat increases expression ISO RGD:1354369 6480464 panobinostat results in increased expression of HEY2 mRNA CTD PMID:26272509 paracetamol increases expression ISO RGD:1354369 6480464 Acetaminophen results in increased expression of HEY2 mRNA CTD PMID:21420995 more ... paracetamol increases expression EXP 6480464 Acetaminophen results in increased expression of HEY2 mRNA CTD PMID:33387578 paraquat multiple interactions ISO RGD:1553745 6480464 [LRRK2 protein mutant form co-treated with Maneb co-treated with Paraquat] results in decreased expression of HEY2 mRNA, [Maneb co-treated with Paraquat] results in decreased expression of HEY2 mRNA CTD PMID:23017109 , PMID:36117858 phenylephrine multiple interactions ISO RGD:1553745 6480464 HEY2 protein inhibits the reaction [Phenylephrine results in increased expression of MYH7 mRNA] more ... CTD PMID:16603706 phenylephrine decreases expression ISO RGD:1553745 6480464 Phenylephrine results in decreased expression of HEY2 mRNA CTD PMID:16603706 phenylephrine decreases response to substance ISO RGD:1553745 6480464 HEY2 protein results in decreased susceptibility to Phenylephrine CTD PMID:16603706 , PMID:20001863 poly(I:C) multiple interactions EXP 6480464 [Poly I-C co-treated with HU 211] results in decreased expression of HEY2 mRNA CTD PMID:26923065 raloxifene multiple interactions ISO RGD:1354369 6480464 Raloxifene Hydrochloride inhibits the reaction [Estradiol results in increased expression of HEY2 mRNA] CTD PMID:21185374 S-(1,2-dichlorovinyl)-L-cysteine multiple interactions ISO RGD:1354369 6480464 [S-(1 more ... CTD PMID:35811015 SB 431542 multiple interactions ISO RGD:1354369 6480464 [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 topotecan multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in increased expression of HEY2 mRNA CTD PMID:25729387 trichloroethene increases expression EXP 6480464 Trichloroethylene results in increased expression of HEY2 mRNA CTD PMID:33387578 triclosan decreases expression ISO RGD:1354369 6480464 Triclosan results in decreased expression of HEY2 mRNA CTD PMID:30510588 triptonide increases expression ISO RGD:1553745 6480464 triptonide results in increased expression of HEY2 mRNA CTD PMID:33045310 urethane increases expression ISO RGD:1354369 6480464 Urethane results in increased expression of HEY2 mRNA CTD PMID:28818685 valproic acid increases expression ISO RGD:1553745 6480464 Valproic Acid results in increased expression of HEY2 mRNA CTD PMID:20219112 valproic acid decreases expression ISO RGD:1354369 6480464 Valproic Acid results in decreased expression of HEY2 mRNA CTD PMID:23179753 valproic acid affects expression ISO RGD:1354369 6480464 Valproic Acid affects the expression of HEY2 mRNA CTD PMID:25979313 valproic acid increases expression ISO RGD:1354369 6480464 Valproic Acid results in increased expression of HEY2 mRNA CTD PMID:23179753 more ... valproic acid multiple interactions ISO RGD:1354369 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of HEY2 mRNA CTD PMID:27188386
