Gene: Tacr1 (tachykinin receptor 1) Rattus norvegicus
Symbol: Tacr1
Name: tachykinin receptor 1
Description: Exhibits substance P receptor activity; involved in several processes, including learning or memory, positive regulation of cell communication, and regulation of cell motility; localizes to several cellular components, including the cell body, cell surface, and cytoplasm; used to study central sleep apnea, cystitis, pancreatitis, and pulmonary hypertension; biomarker of allergic rhinitis, asthma, colitis, and respiratory syncytial virus infectious disease; orthologous to human TACR1 (tachykinin receptor 1); PARTICIPATES IN calcium/calcium-mediated signaling pathway; measles pathway; INTERACTS WITH (S)-amphetamine; (S)-nicotine; 1,2-Naphthoquinone.
Type: protein-coding
Also known as: neurokinin 1 receptor; NK-1 receptor; NK-1R; SPR; substance p receptor; substance-P receptor; Tac1r; Tachykinin 1 receptor; Tachykinin 1 receptor (substance P receptor neurokinin 1 receptor); Tachykinin 1 receptor (substance P receptor neurokinin 1 receptor) see also D4Mgh17 D4Wox19 and D4Mit23
Homo sapiens (human) : TACR1 (tachykinin receptor 1)  HGNC  Alliance
Mus musculus (house mouse) : Tacr1 (tachykinin receptor 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tacr1 (tachykinin receptor 1)
Pan paniscus (bonobo/pygmy chimpanzee) : TACR1 (tachykinin receptor 1)
Canis lupus familiaris (dog) : TACR1 (tachykinin receptor 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tacr1 (tachykinin receptor 1)
Sus scrofa (pig) : TACR1 (tachykinin receptor 1)
more info ...
Is Marker For: Strains:   BB.SHR-(D4Got41-Tacr1)/K  
QTLs:   Bw52  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.04113,247,236 - 113,416,139 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.04177,926,094 - 178,095,041 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44116,610,595 - 116,780,394 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.14116,855,058 - 117,024,964 (+)NCBI
Celera4103,918,032 - 104,086,347 (+)NCBICelera
Cytogenetic Map4q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Related Rat Strains
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Tacr1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 3811
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.