Tacr1 (tachykinin receptor 1) - Rat Genome Database

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Gene: Tacr1 (tachykinin receptor 1) Heterocephalus glaber
Analyze
Symbol: Tacr1
Name: tachykinin receptor 1
RGD ID: 18910209
Description: ENCODES a protein that exhibits substance P receptor activity (ortholog); INVOLVED IN aggressive behavior (ortholog); angiotensin-mediated drinking behavior (ortholog); associative learning (ortholog); ASSOCIATED WITH Acute Lung Injury (ortholog); acute necrotizing pancreatitis (ortholog); alcohol use disorder (ortholog); FOUND IN cell body (ortholog); cell periphery (ortholog); cell surface (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Substance-P receptor
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474928,243,640 - 28,455,086 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474928,243,667 - 28,455,012 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
aggressive behavior  (ISO)
angiotensin-mediated drinking behavior  (ISO)
associative learning  (ISO)
behavioral response to pain  (ISO)
eating behavior  (ISO)
learning or memory  (ISO)
long-term memory  (ISO)
operant conditioning  (ISO)
positive regulation of action potential  (ISO)
positive regulation of blood pressure  (ISO)
positive regulation of cytosolic calcium ion concentration  (ISO)
positive regulation of epithelial cell migration  (ISO)
positive regulation of epithelial cell proliferation  (ISO)
positive regulation of flagellated sperm motility  (ISO)
positive regulation of hormone secretion  (ISO)
positive regulation of leukocyte migration  (ISO)
positive regulation of lymphocyte proliferation  (ISO)
positive regulation of ossification  (ISO)
positive regulation of stress fiber assembly  (ISO)
positive regulation of synaptic transmission, cholinergic  (ISO)
positive regulation of synaptic transmission, GABAergic  (ISO)
positive regulation of uterine smooth muscle contraction  (ISO)
positive regulation of vascular permeability  (ISO)
positive regulation of vasoconstriction  (ISO)
regulation of blood pressure  (ISO)
regulation of smooth muscle cell migration  (ISO)
regulation of smooth muscle cell proliferation  (ISO)
regulation of uterine smooth muscle contraction  (ISO)
response to auditory stimulus  (ISO)
response to electrical stimulus  (ISO)
response to estradiol  (ISO)
response to ethanol  (ISO)
response to hormone  (ISO)
response to nicotine  (ISO)
response to organic cyclic compound  (ISO)
response to ozone  (ISO)
response to pain  (ISO)
response to progesterone  (ISO)
smooth muscle contraction involved in micturition  (ISO)
sperm ejaculation  (ISO)
tachykinin receptor signaling pathway  (ISO)

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:21993625   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Tacr1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474928,243,640 - 28,455,086 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474928,243,667 - 28,455,012 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
TACR1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38275,046,463 - 75,199,520 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl275,046,463 - 75,199,520 (-)EnsemblGRCh38hg38GRCh38
GRCh37275,273,590 - 75,426,646 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36275,129,738 - 75,279,781 (-)NCBINCBI36Build 36hg18NCBI36
Build 34275,189,817 - 75,337,838NCBI
Celera275,104,880 - 75,257,954 (-)NCBICelera
Cytogenetic Map2p12NCBI
HuRef275,010,440 - 75,164,411 (-)NCBIHuRef
CHM1_1275,202,888 - 75,356,007 (-)NCBICHM1_1
T2T-CHM13v2.0275,055,302 - 75,208,694 (-)NCBIT2T-CHM13v2.0
Tacr1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39682,378,990 - 82,537,085 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl682,379,315 - 82,537,085 (+)EnsemblGRCm39 Ensembl
GRCm38682,402,003 - 82,560,104 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl682,402,334 - 82,560,104 (+)EnsemblGRCm38mm10GRCm38
MGSCv37682,352,469 - 82,510,098 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36682,368,133 - 82,525,757 (+)NCBIMGSCv36mm8
Celera684,384,420 - 84,542,486 (+)NCBICelera
Cytogenetic Map6C3NCBI
cM Map635.94NCBI
Tacr1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84116,478,617 - 116,647,492 (+)NCBIGRCr8
mRatBN7.24114,920,844 - 115,089,733 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4114,920,844 - 115,089,733 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4120,383,645 - 120,552,243 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04116,158,843 - 116,327,453 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04114,778,790 - 114,948,892 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04113,247,236 - 113,416,139 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4113,247,795 - 113,414,504 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04177,926,094 - 178,095,041 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44116,610,595 - 116,780,394 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.14116,855,058 - 117,024,964 (+)NCBI
Celera4103,918,032 - 104,086,347 (+)NCBICelera
Cytogenetic Map4q34NCBI
Tacr1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542410,614,340 - 10,761,872 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542410,614,340 - 10,761,872 (+)NCBIChiLan1.0ChiLan1.0
TACR1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21251,188,457 - 51,344,443 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A51,191,211 - 51,347,197 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A75,111,339 - 75,267,320 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A76,614,478 - 76,771,018 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A76,614,478 - 76,771,018 (-)Ensemblpanpan1.1panPan2
TACR1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11748,038,010 - 48,178,971 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1748,038,010 - 48,178,971 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1747,681,510 - 47,821,826 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01748,900,538 - 49,041,473 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1748,899,743 - 49,044,192 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11747,916,025 - 48,056,577 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01747,980,726 - 48,121,228 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01748,542,868 - 48,683,479 (+)NCBIUU_Cfam_GSD_1.0
Tacr1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244062929,315,839 - 9,471,281 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365561,266,613 - 1,421,275 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365561,266,621 - 1,421,271 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TACR1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl367,839,411 - 68,021,724 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1367,839,367 - 68,021,733 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
TACR1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11432,080,319 - 32,236,556 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1432,083,615 - 32,233,596 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604579,940,541 - 80,098,197 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_004844651 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AHKG01030201 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01030202 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01030203 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01030204 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01030205 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01030206 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01030207 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01030208 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01030209 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01030210 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01030211 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01030212 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01030213 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01030214 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01030215 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01030216 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01030217 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01030218 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01030219 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JH172835 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSHGLT00000006915   ⟹   ENSHGLP00000006831
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462474928,243,640 - 28,455,086 (+)Ensembl
RefSeq Acc Id: XM_004844651   ⟹   XP_004844708
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474928,243,667 - 28,455,012 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004844708 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB15379 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000006831
RefSeq Acc Id: XP_004844708   ⟸   XM_004844651
Ensembl Acc Id: ENSHGLP00000006831   ⟸   ENSHGLT00000006915


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000004985 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000006915 ENTREZGENE
NCBI Gene Tacr1 ENTREZGENE
UniProt A0AAX6P6C9_HETGA UniProtKB/TrEMBL