Gene: Grm8 (glutamate metabotropic receptor 8) Rattus norvegicus
Symbol: Grm8
Name: glutamate metabotropic receptor 8
Description: ENCODES a protein that exhibits group III metabotropic glutamate receptor activity; G-protein coupled receptor activity (ortholog); glutamate receptor activity (ortholog); INVOLVED IN chemical synaptic transmission; detection of mechanical stimulus involved in sensory perception of pain; regulation of neurotransmitter secretion; PARTICIPATES IN glutamate signaling pathway; ASSOCIATED WITH Epilepsy; Parkinsonian Disorders; Seizures; FOUND IN integral component of plasma membrane; neuron projection; neuronal cell body; INTERACTS WITH (+)-pilocarpine; (S)-amphetamine; 6-propyl-2-thiouracil
Type: protein-coding
Also known as: G protein-coupled receptor family C group 1 member H; G protein-coupled receptor, family C, group 1, member H; Glur8; glutamate receptor, metabotropic 8; Gprc1h; metabotropic glutamate receptor 8; metabotropic glutamate receptor subtype 8b; mGlur; Mglur8; mGluR8b
Homo sapiens (human) : GRM8 (glutamate metabotropic receptor 8)  HGNC  Alliance
Mus musculus (house mouse) : Grm8 (glutamate receptor, metabotropic 8)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Grm8 (glutamate metabotropic receptor 8)
Canis lupus familiaris (dog) : GRM8 (glutamate metabotropic receptor 8)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Grm8 (glutamate metabotropic receptor 8)
more info ...
Is Marker For: Strains:   WI-Grm8em1Geh  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0454,474,344 - 55,409,526 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0454,226,315 - 55,151,544 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4453,976,781 - 54,902,331 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1454,207,857 - 55,152,488 (-)NCBI
Celera450,936,284 - 51,838,440 (-)NCBICelera
Cytogenetic Map4q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Related Rat Strains
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
More on Grm8
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 619858
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2018-03-13
Status: ACTIVE