Il12rb2 (interleukin 12 receptor subunit beta 2) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: Il12rb2 (interleukin 12 receptor subunit beta 2) Rattus norvegicus
Analyze
Symbol: Il12rb2
Name: interleukin 12 receptor subunit beta 2
RGD ID: 620026
Description: Predicted to enable several functions, including coreceptor activity; cytokine receptor activity; and protein kinase binding activity. Predicted to be involved in interleukin-12-mediated signaling pathway and positive regulation of type II interferon production. Predicted to act upstream of or within response to cytokine and response to lipopolysaccharide. Predicted to be located in plasma membrane. Predicted to be part of receptor complex. Predicted to be active in external side of plasma membrane. Orthologous to human IL12RB2 (interleukin 12 receptor subunit beta 2); PARTICIPATES IN interleukin-12 signaling pathway; interleukin-27 signaling pathway; cytokine mediated signaling pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: interleukin 12 receptor, beta 2; interleukin-12 receptor subunit beta-2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8497,756,089 - 97,844,937 (-)NCBIGRCr8
mRatBN7.2496,426,396 - 96,515,251 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl496,426,842 - 96,515,289 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4101,682,750 - 101,748,342 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0497,457,722 - 97,523,310 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0495,881,608 - 95,947,275 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0498,049,195 - 98,141,562 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl498,052,842 - 98,141,482 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04162,835,618 - 162,927,057 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4496,929,755 - 96,995,733 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1497,174,599 - 97,182,220 (-)NCBI
Celera491,119,174 - 91,184,692 (-)NCBICelera
Cytogenetic Map4q31NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Role of beta1 and beta2 subunits of the interleukin-12 receptor in determining T helper 1/T helper 2 responses in vivo in the rat. Gillespie KM, etal., Immunology 2000 Jan;99(1):109-12.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
6. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
7. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
8. GOA pipeline RGD automated data pipeline
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:11114383   PMID:11489994   PMID:15220916  


Genomics

Comparative Map Data
Il12rb2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8497,756,089 - 97,844,937 (-)NCBIGRCr8
mRatBN7.2496,426,396 - 96,515,251 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl496,426,842 - 96,515,289 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4101,682,750 - 101,748,342 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0497,457,722 - 97,523,310 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0495,881,608 - 95,947,275 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0498,049,195 - 98,141,562 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl498,052,842 - 98,141,482 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04162,835,618 - 162,927,057 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4496,929,755 - 96,995,733 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1497,174,599 - 97,182,220 (-)NCBI
Celera491,119,174 - 91,184,692 (-)NCBICelera
Cytogenetic Map4q31NCBI
IL12RB2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38167,307,364 - 67,398,724 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl167,307,364 - 67,398,724 (+)EnsemblGRCh38hg38GRCh38
GRCh37167,773,047 - 67,864,407 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36167,545,635 - 67,635,171 (+)NCBINCBI36Build 36hg18NCBI36
Build 34167,485,067 - 67,574,604NCBI
Celera166,062,815 - 66,152,324 (+)NCBICelera
Cytogenetic Map1p31.3NCBI
HuRef165,882,963 - 65,972,440 (+)NCBIHuRef
CHM1_1167,888,407 - 67,977,959 (+)NCBICHM1_1
T2T-CHM13v2.0167,181,083 - 67,276,270 (+)NCBIT2T-CHM13v2.0
Il12rb2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39667,263,914 - 67,353,277 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl667,268,302 - 67,353,172 (-)EnsemblGRCm39 Ensembl
GRCm38667,285,986 - 67,376,293 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl667,291,318 - 67,376,188 (-)EnsemblGRCm38mm10GRCm38
MGSCv37667,242,012 - 67,326,131 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36667,221,596 - 67,305,715 (-)NCBIMGSCv36mm8
Celera669,414,576 - 69,494,819 (-)NCBICelera
Cytogenetic Map6C1NCBI
cM Map630.81NCBI
Il12rb2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495542323,774,557 - 23,806,744 (-)NCBIChiLan1.0ChiLan1.0
IL12RB2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21159,467,321 - 159,559,572 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11158,615,544 - 158,719,401 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0166,549,650 - 66,640,623 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1168,543,509 - 68,612,168 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl168,543,509 - 68,612,168 (-)Ensemblpanpan1.1panPan2
IL12RB2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1543,197,034 - 43,269,571 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl543,197,034 - 43,257,594 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha543,385,096 - 43,448,024 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0543,381,977 - 43,454,682 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl543,381,997 - 43,442,686 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1543,348,361 - 43,411,066 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0543,295,000 - 43,357,916 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0543,534,014 - 43,597,143 (-)NCBIUU_Cfam_GSD_1.0
Il12rb2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505880,164,929 - 80,254,074 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049365914,238,720 - 4,310,847 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
IL12RB2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl6145,212,981 - 145,281,791 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.16145,210,251 - 145,292,399 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.26134,096,042 - 134,163,740 (-)NCBISscrofa10.2Sscrofa10.2susScr3
IL12RB2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12065,711,298 - 65,805,963 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2065,714,618 - 65,791,681 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603351,799,834 - 51,897,169 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Il12rb2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474227,832,883 - 27,865,139 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474227,830,691 - 27,865,176 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Il12rb2
342 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:91
Count of miRNA genes:79
Interacting mature miRNAs:82
Transcripts:ENSRNOT00000009883
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2303168Bp330Blood pressure QTL 3304.250.017arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)45214602146446691Rat
2316958Gluco58Glucose level QTL 5810blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)411320076180699135Rat
12798520Anxrr55Anxiety related response QTL 554.450.01locomotor behavior trait (VT:0001392)number of rearing movements with lid-pushing in an experimental apparatus (CMO:0002715)432583980114627242Rat
8655961Kidm43Kidney mass QTL 4318kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)436303261103194984Rat
1358352Srcrt3Stress Responsive Cort QTL 32.29blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)438465774146803430Rat
1300139Hrtrt6Heart rate QTL 62.85heart pumping trait (VT:2000009)heart rate (CMO:0000002)439524264116179656Rat
1576305Emca6Estrogen-induced mammary cancer QTL 65.8mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)444463720155883716Rat
1354612Foco1Food consumption QTL 18.87eating behavior trait (VT:0001431)food intake rate (CMO:0000427)444463908148090542Rat
1354660Salc1Saline consumption QTL 111.26drinking behavior trait (VT:0001422)saline drink intake rate (CMO:0001627)444463908148090542Rat
2312567Glom19Glomerulus QTL 191.90.006kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)445456990146803430Rat
1298082Stresp4Stress response QTL 4blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)450119848146803430Rat
70200Alc18Alcohol consumption QTL 189.2drinking behavior trait (VT:0001422)ethanol intake volume to total fluid intake volume ratio (CMO:0001591)456647873149491524Rat
1641833Alc21Alcohol consumption QTL 218.60.0001drinking behavior trait (VT:0001422)ethanol drink intake rate (CMO:0001407)456698790126192555Rat
1358363Sradr3Stress Responsive Adrenal Weight QTL 36.19adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)457486946102486946Rat
738009Sach4Saccharine consumption QTL 44.90.000016consumption behavior trait (VT:0002069)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)459948935154902892Rat
738016Alc16Alcohol consumption QTL 163.60.00015consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)459948935154902892Rat
738031Alc14Alcohol consumption QTL 147.60.00003consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)459948935154902892Rat
1578657Bss12Bone structure and strength QTL 128.9femur morphology trait (VT:0000559)femoral neck cross-sectional area (CMO:0001697)460220938105220938Rat
1578658Bss13Bone structure and strength QTL 138femur strength trait (VT:0010010)femoral neck polar moment of inertia (CMO:0001670)460220938105220938Rat
2300179Bmd50Bone mineral density QTL 505.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)460928534105928534Rat
1549843Bw53Body weight QTL 530.0001body mass (VT:0001259)body weight gain (CMO:0000420)461697658103194791Rat
1549839Bw52Body weight QTL 520.0001body mass (VT:0001259)body weight gain (CMO:0000420)461697658115089733Rat
61418Pia5Pristane induced arthritis QTL 54.5joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)462277855128289560Rat
6478743Anxrr40Anxiety related response QTL 400.83076defecation behavior trait (VT:0010462)defecation rate (CMO:0000998)462753847107753847Rat
6478772Anxrr49Anxiety related response QTL 490.15488defecation behavior trait (VT:0010462)defecation rate (CMO:0000998)462753847107753847Rat
6478684Anxrr30Anxiety related response QTL 300.00087defecation behavior trait (VT:0010462)defecation rate (CMO:0000998)462753847107753847Rat
631651Bp124Blood pressure QTL 1243arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)462879517107879517Rat
70192BpQTLcluster5Blood pressure QTL cluster 54.183arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)462933508114921294Rat
70192BpQTLcluster5Blood pressure QTL cluster 54.183arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)462933508114921294Rat
70192BpQTLcluster5Blood pressure QTL cluster 54.183arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)462933508114921294Rat
70192BpQTLcluster5Blood pressure QTL cluster 54.183arterial blood pressure trait (VT:2000000)percent change in mean arterial blood pressure (CMO:0002035)462933508114921294Rat
70192BpQTLcluster5Blood pressure QTL cluster 54.183arterial blood pressure trait (VT:2000000)percent change in systolic blood pressure (CMO:0000747)462933508114921294Rat
70192BpQTLcluster5Blood pressure QTL cluster 54.183arterial blood pressure trait (VT:2000000)absolute change in pulse pressure (CMO:0001882)462933508114921294Rat
70192BpQTLcluster5Blood pressure QTL cluster 54.183arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)462933508114921294Rat
631674Iddm14Insulin dependent diabetes mellitus QTL 14blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)464528739157573521Rat
61330Eau1Experimental allergic uveoretinitis QTL 10.0003uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)470362013132642728Rat
634344Hcar7Hepatocarcinoma resistance QTL 77.8liver integrity trait (VT:0010547)liver tumorous lesion area to total liver area ratio (CMO:0001075)470808386115808386Rat
634344Hcar7Hepatocarcinoma resistance QTL 77.8liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)470808386115808386Rat
631646Stl4Serum triglyceride level QTL 46.50.0001blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)473169846132642728Rat
724522Bp146Blood pressure QTL 1462.20.0021arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)473630210118630210Rat
2302051Pia28Pristane induced arthritis QTL 285.30.001blood autoantibody amount (VT:0003725)serum immunoglobulin G-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002112)473630210118630210Rat
70167Bw22Body weight QTL 223.1body mass (VT:0001259)body weight (CMO:0000012)476647384117676292Rat
1357342Bw40Body weight QTL 400.001body mass (VT:0001259)body weight (CMO:0000012)476647384117676292Rat
631662Hcar2Hepatocarcinoma resistance QTL 23.10.0003liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)478878504123878504Rat
631556Bp135Blood pressure QTL 1350.017arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)478881294117676292Rat
61364Iddm2Insulin dependent diabetes mellitus QTL 2blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)478885890102684881Rat
738015Pia9Pristane induced arthritis QTL 94.50.048joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)480694870125694870Rat
2306899Bp338Blood pressure QTL 3380.071arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)481006124120102625Rat
1641919Alc22Alcohol consumption QTL 220.0005drinking behavior trait (VT:0001422)ethanol drink intake rate (CMO:0001407)481192555126192555Rat
70177Xhs1X-ray hypersensitivity QTL 125.1intestine integrity trait (VT:0010554)post-insult time to onset of moribundity (CMO:0001896)482798864152731274Rat
1576316Ept5Estrogen-induced pituitary tumorigenesis QTL 53.8pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)483428419177635233Rat
634334Xhs3X-ray hypersensitivity QTL 310intestine integrity trait (VT:0010554)post-insult time to onset of moribundity (CMO:0001896)484728680129854654Rat
1582232Gluco25Glucose level QTL 253.60.0023blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)485253748148090731Rat
12798523Anxrr56Anxiety related response QTL 562.830.05locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)485253748150276390Rat
1358202Gluco11Glucose level QTL 112.40.02adipocyte glucose uptake trait (VT:0004185)absolute change in adipocyte glucose uptake (CMO:0000873)485379421167139601Rat
61476Aia3Adjuvant induced arthritis QTL 33.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)486730991131730991Rat
1578662Bss15Bone structure and strength QTL 1519.6femur width (VT:1000666)femoral neck width (CMO:0001695)487327165132327165Rat
1578670Bss14Bone structure and strength QTL 1416.4femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)487327165132327165Rat
2317587Eae26Experimental allergic encephalomyelitis QTL 26nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)488656681103194984Rat
1578655Bmd11Bone mineral density QTL 1111femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)490850165135850165Rat
634335Anxrr16Anxiety related response QTL 167.22locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)493308457167139447Rat
631689Scl4Serum cholesterol level QTL 41.90.008blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)495174120140174120Rat

Markers in Region
D4Uia8  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2496,433,861 - 96,434,152 (+)MAPPERmRatBN7.2
Rnor_6.0498,059,834 - 98,060,124NCBIRnor6.0
Rnor_5.04162,845,444 - 162,845,734UniSTSRnor5.0
RGSC_v3.4496,936,547 - 96,936,838RGDRGSC3.4
RGSC_v3.4496,936,548 - 96,936,838UniSTSRGSC3.4
RGSC_v3.1497,181,028 - 97,181,319RGD
Celera491,125,967 - 91,126,257UniSTS
Cytogenetic Map4q31UniSTS
Rab7-ps1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24120,462,698 - 120,462,929 (+)MAPPERmRatBN7.2
mRatBN7.2496,474,285 - 96,474,514 (+)MAPPERmRatBN7.2
Rnor_6.0498,100,457 - 98,100,685NCBIRnor6.0
Rnor_6.04119,911,199 - 119,911,429NCBIRnor6.0
Rnor_5.04185,159,082 - 185,159,312UniSTSRnor5.0
Rnor_5.04162,886,071 - 162,886,299UniSTSRnor5.0
RGSC_v3.44122,203,418 - 122,203,648UniSTSRGSC3.4
RGSC_v3.4496,977,370 - 96,977,598UniSTSRGSC3.4
Celera491,166,331 - 91,166,559UniSTS
Celera4109,422,096 - 109,422,326UniSTS
Cytogenetic Map4q34UniSTS
Cytogenetic Map4q31UniSTS
BF397528  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2496,467,959 - 96,468,196 (+)MAPPERmRatBN7.2
Rnor_6.0498,094,131 - 98,094,367NCBIRnor6.0
Rnor_5.04162,879,745 - 162,879,981UniSTSRnor5.0
RGSC_v3.4496,971,044 - 96,971,280UniSTSRGSC3.4
Celera491,160,077 - 91,160,313UniSTS
RH 3.4 Map4606.8UniSTS
Cytogenetic Map4q31UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 22 4 2 7 2 7 7 43 10 4 2 7
Low 3 15 29 15 12 15 1 4 23 25 32 9 1
Below cutoff 6 18 18 18 6 4

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000009883   ⟹   ENSRNOP00000009883
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl496,426,842 - 96,515,289 (-)Ensembl
Rnor_6.0 Ensembl498,052,842 - 98,141,482 (-)Ensembl
RefSeq Acc Id: NM_001191750   ⟹   NP_001178679
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8497,756,762 - 97,822,339 (-)NCBI
mRatBN7.2496,427,069 - 96,492,651 (-)NCBI
Rnor_6.0498,053,041 - 98,118,819 (-)NCBI
Rnor_5.04162,835,618 - 162,927,057 (-)NCBI
Celera491,119,174 - 91,184,692 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001412558   ⟹   NP_001399487
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8497,756,089 - 97,844,937 (-)NCBI
mRatBN7.2496,426,396 - 96,515,251 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001178679 (Get FASTA)   NCBI Sequence Viewer  
  NP_001399487 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAD16040 (Get FASTA)   NCBI Sequence Viewer  
  EDL91574 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000009883
  ENSRNOP00000009883.5
Reference Protein Sequences
RefSeq Acc Id: NP_001178679   ⟸   NM_001191750
- Peptide Label: precursor
- UniProtKB: F1LRH7 (UniProtKB/TrEMBL),   A6KF50 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000009883   ⟸   ENSRNOT00000009883
RefSeq Acc Id: NP_001399487   ⟸   NM_001412558
- Peptide Label: precursor
- UniProtKB: F1LRH7 (UniProtKB/TrEMBL)
Protein Domains
Fibronectin type-III

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-F1LRH7-F1-model_v2 AlphaFold F1LRH7 1-869 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620026 AgrOrtholog
BioCyc Gene G2FUF-44562 BioCyc
Ensembl Genes ENSRNOG00000007270 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000009883 ENTREZGENE
  ENSRNOT00000009883.7 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
InterPro Fibronectin_type3 UniProtKB/TrEMBL
  FN3_sf UniProtKB/TrEMBL
  Hematopoietin_rcpt_Gp130_CS UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  IgC2-like_lig-bd UniProtKB/TrEMBL
KEGG Report rno:171334 UniProtKB/TrEMBL
NCBI Gene 171334 ENTREZGENE
PANTHER CYTOKINE RECEPTOR UniProtKB/TrEMBL
  INTERLEUKIN-12 RECEPTOR SUBUNIT BETA-2 UniProtKB/TrEMBL
Pfam fn3 UniProtKB/TrEMBL
  Lep_receptor_Ig UniProtKB/TrEMBL
PhenoGen Il12rb2 PhenoGen
PROSITE FN3 UniProtKB/TrEMBL
  HEMATOPO_REC_L_F2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000007270 RatGTEx
SMART FN3 UniProtKB/TrEMBL
Superfamily-SCOP FN_III-like UniProtKB/TrEMBL
UniProt A6KF50 ENTREZGENE, UniProtKB/TrEMBL
  F1LRH7 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-12-16 Il12rb2  interleukin 12 receptor subunit beta 2  Il12rb2  interleukin 12 receptor, beta 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-09-10 Il12rb2  interleukin 12 receptor, beta 2      Symbol and Name status set to approved 1299863 APPROVED
2002-08-07 Il12rb2  interleukin 12 receptor, beta 2      Symbol and Name status set to provisional 70820 PROVISIONAL