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Gene: IL12RB2 (interleukin 12 receptor subunit beta 2) Homo sapiens
Symbol: IL12RB2
Name: interleukin 12 receptor subunit beta 2
Description: Predicted to have cytokine binding activity and cytokine receptor activity. Involved in positive regulation of interferon-gamma production. Localizes to the plasma membrane.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: IL-12 receptor beta 2; IL-12 receptor subunit beta-2; IL-12R subunit beta-2; IL-12R-beta-2; IL-12RB2; interleukin 12 receptor, beta 2; interleukin-12 receptor beta-2 chain; interleukin-12 receptor subunit beta-2; RP11-102M16.1
Mus musculus (house mouse) : Il12rb2 (interleukin 12 receptor, beta 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Il12rb2 (interleukin 12 receptor subunit beta 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Il12rb2 (interleukin 12 receptor subunit beta 2)
Pan paniscus (bonobo/pygmy chimpanzee) : IL12RB2 (interleukin 12 receptor subunit beta 2)
Canis lupus familiaris (dog) : IL12RB2 (interleukin 12 receptor subunit beta 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Il12rb2 (interleukin 12 receptor subunit beta 2)
Sus scrofa (pig) : IL12RB2 (interleukin 12 receptor subunit beta 2)
Chlorocebus sabaeus (African green monkey) : IL12RB2 (interleukin 12 receptor subunit beta 2)
Heterocephalus glaber (naked mole-rat) : Il12rb2 (interleukin 12 receptor subunit beta 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl167,307,364 - 67,397,090 (+)EnsemblGRCh38hg38GRCh38
GRCh38167,307,351 - 67,398,724 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37167,773,047 - 67,862,583 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36167,545,635 - 67,635,171 (+)NCBINCBI36hg18NCBI36
Build 34167,485,067 - 67,574,604NCBI
Celera166,062,815 - 66,152,324 (+)NCBI
Cytogenetic Map1p31.3NCBI
HuRef165,882,963 - 65,972,440 (+)NCBIHuRef
CHM1_1167,888,407 - 67,977,959 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on IL12RB2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1346577
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-03-24
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.