Gene: KCNK1 (potassium two pore domain channel subfamily K member 1) Homo sapiens
Symbol: KCNK1
Name: potassium two pore domain channel subfamily K member 1
Description: This gene encodes one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. The product of this gene has not been shown to be a functional channel, however, it may require other non-pore-forming proteins for activity. [provided by RefSeq, Jul 2008]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: DPK; HOHO; inward rectifying potassium channel protein TWIK-1; K2P1; K2p1.1; KCNO1; potassium channel K2P1; potassium channel KCNO1; potassium channel subfamily K member 1; potassium channel, two pore domain subfamily K, member 1; potassium inwardly-rectifying channel, subfamily K, member 1; tandem of P domains in a weak inward rectifying K+ channel 1; TWIK-1; TWIK1
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh381233,614,004 - 233,672,512 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371233,749,750 - 233,808,258 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361231,816,373 - 231,874,607 (+)NCBINCBI36hg18NCBI36
Build 341230,056,484 - 230,114,719NCBI
Celera1207,020,005 - 207,078,507 (+)NCBI
Cytogenetic Map1q42.2NCBI
HuRef1204,239,702 - 204,297,905 (+)NCBIHuRef
CHM1_11235,023,248 - 235,081,757 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on KCNK1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 731790
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-05-14
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.