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Gene: Il12rb2 (interleukin 12 receptor, beta 2) Mus musculus
Symbol: Il12rb2
Name: interleukin 12 receptor, beta 2
Description: Exhibits protein kinase binding activity. Involved in several processes, including interferon-gamma production; peptidyl-tyrosine phosphorylation; and response to lipopolysaccharide. Localizes to the external side of plasma membrane. Is expressed in several structures, including brain ventricular layer; genitourinary system; incisor; olfactory epithelium; and submandibular gland. Orthologous to human IL12RB2 (interleukin 12 receptor subunit beta 2); PARTICIPATES IN interleukin-12 signaling pathway; interleukin-27 signaling pathway; Jak-Stat signaling pathway; INTERACTS WITH 1-chloro-2,4,6-trinitrobenzene; 1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: A930027I18Rik; Ifnm; IL-12 receptor subunit beta-2; IL-12R subunit beta-2; IL-12R-beta-2; IL-12RB2; interferon response to microorganisms; interleukin-12 receptor subunit beta-2
Homo sapiens (human) : IL12RB2 (interleukin 12 receptor subunit beta 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Il12rb2 (interleukin 12 receptor subunit beta 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Il12rb2 (interleukin 12 receptor subunit beta 2)
Pan paniscus (bonobo/pygmy chimpanzee) : IL12RB2 (interleukin 12 receptor subunit beta 2)
Canis lupus familiaris (dog) : IL12RB2 (interleukin 12 receptor subunit beta 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Il12rb2 (interleukin 12 receptor subunit beta 2)
Sus scrofa (pig) : IL12RB2 (interleukin 12 receptor subunit beta 2)
Chlorocebus sabaeus (green monkey) : IL12RB2 (interleukin 12 receptor subunit beta 2)
Heterocephalus glaber (naked mole-rat) : Il12rb2 (interleukin 12 receptor subunit beta 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl667,291,318 - 67,376,188 (-)Ensembl
GRCm38667,285,986 - 67,376,293 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37667,242,012 - 67,326,131 (-)NCBIGRCm37mm9NCBIm37
MGSCv36667,221,596 - 67,305,715 (-)NCBImm8
Celera669,414,576 - 69,494,819 (-)NCBICelera
Cytogenetic Map6 C1NCBI
cM Map630.81NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Il12rb2
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1552409
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.