Gene: Ppp3ca (protein phosphatase 3 catalytic subunit alpha) Rattus norvegicus
Symbol: Ppp3ca
Name: protein phosphatase 3 catalytic subunit alpha
Description: ENCODES a protein that exhibits calcium-dependent protein serine/threonine phosphatase activity; calmodulin binding; calmodulin-dependent protein phosphatase activity; INVOLVED IN aging; brain development; cellular response to glucose stimulus; PARTICIPATES IN calcineurin signaling pathway; dopamine signaling pathway; interleukin-12 signaling pathway; ASSOCIATED WITH cardiac hypertrophy; ASSOCIATED WITH Brain Injuries; kidney disease; Reperfusion Injury; FOUND IN calcineurin complex; cytosol; slit diaphragm; INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine
Type: protein-coding
Also known as: calcineurin subunit A alpha; calmodulin-dependent calcineurin A subunit alpha isoform; Calna1; CAM-PRP catalytic subunit; protein phosphatase 3 (formerly 2B), catalytic subunit, alpha isoform; protein phosphatase 3, catalytic subunit, alpha isoform; protein phosphatase 3, catalytic subunit, alpha isozyme; protein phosphatase-2Ba; serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform
Homo sapiens (human) : PPP3CA (protein phosphatase 3 catalytic subunit alpha)  HGNC  Alliance
Mus musculus (house mouse) : Ppp3ca (protein phosphatase 3, catalytic subunit, alpha isoform)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ppp3ca (protein phosphatase 3 catalytic subunit alpha)
Pan paniscus (bonobo/pygmy chimpanzee) : PPP3CA (protein phosphatase 3 catalytic subunit alpha)
Canis lupus familiaris (dog) : PPP3CA (protein phosphatase 3 catalytic subunit alpha)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ppp3ca (protein phosphatase 3 catalytic subunit alpha)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.02241,909,332 - 242,186,861 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.02260,463,144 - 260,737,186 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42234,130,176 - 234,409,232 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12234,116,915 - 234,395,972 (+)NCBI
Celera2217,359,756 - 217,630,340 (+)NCBICelera
Cytogenetic Map2q43NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Ppp3ca
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 3382
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-01-08
Status: ACTIVE