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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3382
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ppp3ca
Name: protein phosphatase 3 catalytic subunit alpha
Acc ID: CHEBI:30621
Term: diarsenic trioxide
Definition: An arsenic oxide in which arsenic and oxygen atoms are present in the ratio 2:3.
Chemical ID: MESH:C006632
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ppp3cadecreases expressionEXP 6480464CTDArsenic Trioxide results in decreased expression of PPP3CA mRNAPMID:29223816
Ppp3caincreases expressionEXP 6480464CTDArsenic Trioxide results in increased expression of PPP3CA proteinPMID:34037972
Ppp3camultiple interactionsEXP 6480464CTDPhloretin inhibits the reaction [Arsenic Trioxide results in increased expression of PPP3CA protein]PMID:34037972
Ppp3caincreases expressionISOPPP3CA (Homo sapiens)6480464CTDArsenic Trioxide results in increased expression of PPP3CA mRNAPMID:17963750
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