Enables ionotropic glutamate receptor binding activity and protein phosphatase 2B binding activity. Involved in positive regulation of AMPA receptor activity. Located in dendrite membrane; postsynaptic density; and postsynaptic membrane. Part of AMPA glutamate receptor complex. Is active in glutamatergic synapse and postsynaptic density membrane. Orthologous to human CACNG8 (calcium voltage-gated channel auxiliary subunit gamma 8); PARTICIPATES IN arrhythmogenic right ventricular cardiomyopathy pathway; dilated cardiomyopathy pathway; hypertrophic cardiomyopathy pathway; INTERACTS WITH 17beta-estradiol; 6-propyl-2-thiouracil; ammonium chloride.
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in decreased expression of CACNG8 mRNA
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in decreased expression of CACNG8 mRNA
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in decreased expression of CACNG8 mRNA
[Toluene co-treated with Xylenes co-treated with ethylbenzene] results in decreased expression of CACNG8 mRNA, [Toluene co-treated with Xylenes co-treated with ethylbenzene] results in increased methylation of CACNG8 gene
[Toluene co-treated with Xylenes co-treated with ethylbenzene] results in decreased expression of CACNG8 mRNA, [Toluene co-treated with Xylenes co-treated with ethylbenzene] results in increased methylation of CACNG8 gene
Patients with Dilated Cardiomyopathy and Sustained Monomorphic Ventricular Tachycardia Show Up-Regulation of KCNN3 and KCNJ2 Genes and CACNG8-Linked Left Ventricular Dysfunction.
