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Gene: Adarb1 (adenosine deaminase, RNA-specific, B1) Rattus norvegicus
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Symbol: Adarb1
Name: adenosine deaminase, RNA-specific, B1
Description: Exhibits double-stranded RNA adenosine deaminase activity; double-stranded RNA binding activity; and identical protein binding activity. Involved in RNA modification; brain development; and positive regulation of mRNA processing. Localizes to nucleolus and nucleoplasm. Used to study obesity and transient cerebral ischemia. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis. Orthologous to human ADARB1 (adenosine deaminase RNA specific B1); PARTICIPATES IN microRNA pathway; INTERACTS WITH 1,2-dimethylhydrazine; 2,3,4,7,8-Pentachlorodibenzofuran; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: Adar2; double stranded RNA specific deaminase RED1; double-stranded RNA-specific editase 1; dsRNA adenosine deaminase; RED1; RNA editing deaminase of glutamate receptors; RNA-editing deaminase 1; RNA-editing enzyme 1
Orthologs:
Homo sapiens (human) : ADARB1 (adenosine deaminase RNA specific B1)  HGNC  Alliance
Mus musculus (house mouse) : Adarb1 (adenosine deaminase, RNA-specific, B1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Adarb1 (adenosine deaminase RNA specific B1)
Pan paniscus (bonobo/pygmy chimpanzee) : ADARB1 (adenosine deaminase RNA specific B1)
Canis lupus familiaris (dog) : ADARB1 (adenosine deaminase RNA specific B1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Adarb1 (adenosine deaminase RNA specific B1)
Sus scrofa (pig) : ADARB1 (adenosine deaminase RNA specific B1)
Chlorocebus sabaeus (African green monkey) : ADARB1 (adenosine deaminase RNA specific B1)
Heterocephalus glaber (naked mole-rat) : Adarb1 (adenosine deaminase RNA specific B1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.02011,972,352 - 12,101,022 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2011,972,381 - 12,101,047 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02014,137,226 - 14,264,945 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42011,616,718 - 11,747,294 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12011,678,671 - 11,744,168 (+)NCBI
Celera2012,725,154 - 12,852,814 (+)NCBICelera
Cytogenetic Map20p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Adarb1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2033
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.