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Gene: ADARB1 (adenosine deaminase RNA specific B1) Homo sapiens
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Symbol: ADARB1
Name: adenosine deaminase RNA specific B1
Description: This gene encodes the enzyme responsible for pre-mRNA editing of the glutamate receptor subunit B by site-specific deamination of adenosines. Studies in rat found that this enzyme acted on its own pre-mRNA molecules to convert an AA dinucleotide to an AI dinucleotide which resulted in a new splice site. Alternative splicing of this gene results in several transcript variants, some of which have been characterized by the presence or absence of an ALU cassette insert and a short or long C-terminal region. [provided by RefSeq, Jul 2008]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ADAR2; adenosine deaminase, RNA specific B1; adenosine deaminase, RNA-specific, B1; adenosine deaminase, RNA-specific, B1 (homolog of rat RED1); adenosine deaminase, RNA-specific, B1 (RED1 homolog rat); double-stranded RNA-specific editase 1; DRABA2; DRADA2; dsRNA adenosine deaminase; dsRNA adenosine deaminase DRADA2; human dsRNA adenosine deaminase DRADA2; RED1; RED1 homolog; RNA editase; RNA editing deaminase 1; RNA-editing deaminase 1; RNA-editing enzyme 1
Orthologs:
Mus musculus (house mouse) : Adarb1 (adenosine deaminase, RNA-specific, B1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Adarb1 (adenosine deaminase, RNA-specific, B1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Adarb1 (adenosine deaminase RNA specific B1)
Pan paniscus (bonobo/pygmy chimpanzee) : ADARB1 (adenosine deaminase RNA specific B1)
Canis lupus familiaris (dog) : ADARB1 (adenosine deaminase RNA specific B1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Adarb1 (adenosine deaminase RNA specific B1)
Sus scrofa (pig) : ADARB1 (adenosine deaminase RNA specific B1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382145,074,578 - 45,226,563 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372146,494,493 - 46,646,478 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362145,318,943 - 45,470,902 (+)NCBINCBI36hg18NCBI36
Build 342145,318,942 - 45,470,902NCBI
Celera2131,601,137 - 31,754,043 (+)NCBI
Cytogenetic Map21q22.3NCBI
HuRef2131,920,569 - 32,018,419 (+)NCBIHuRef
CHM1_12146,055,410 - 46,207,429 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
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Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on ADARB1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 732582
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-09-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.