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Gene: ADARB1 (adenosine deaminase RNA specific B1) Homo sapiens
Symbol: ADARB1
Name: adenosine deaminase RNA specific B1
RGD ID: 732582
Description: Exhibits double-stranded RNA adenosine deaminase activity; double-stranded RNA binding activity; and identical protein binding activity. Involved in several processes, including RNA metabolic process; negative regulation of protein kinase activity by regulation of protein phosphorylation; and positive regulation of viral genome replication. Localizes to cytosol; nucleolus; and nucleoplasm. Biomarker of amyotrophic lateral sclerosis.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ADAR2; adenosine deaminase, RNA specific B1; adenosine deaminase, RNA-specific, B1; adenosine deaminase, RNA-specific, B1 (homolog of rat RED1); adenosine deaminase, RNA-specific, B1 (RED1 homolog rat); double-stranded RNA-specific editase 1; DRABA2; DRADA2; dsRNA adenosine deaminase; dsRNA adenosine deaminase DRADA2; human dsRNA adenosine deaminase DRADA2; NEDHYMS; RED1; RED1 homolog; RNA editase; RNA editing deaminase 1; RNA-editing deaminase 1; RNA-editing enzyme 1
Mus musculus (house mouse) : Adarb1 (adenosine deaminase, RNA-specific, B1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Adarb1 (adenosine deaminase, RNA-specific, B1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Adarb1 (adenosine deaminase RNA specific B1)
Pan paniscus (bonobo/pygmy chimpanzee) : ADARB1 (adenosine deaminase RNA specific B1)
Canis lupus familiaris (dog) : ADARB1 (adenosine deaminase RNA specific B1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Adarb1 (adenosine deaminase RNA specific B1)
Sus scrofa (pig) : ADARB1 (adenosine deaminase RNA specific B1)
Chlorocebus sabaeus (African green monkey) : ADARB1 (adenosine deaminase RNA specific B1)
Heterocephalus glaber (naked mole-rat) : Adarb1 (adenosine deaminase RNA specific B1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl2145,073,853 - 45,226,560 (+)EnsemblGRCh38hg38GRCh38
GRCh382145,074,578 - 45,226,563 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372146,494,493 - 46,646,478 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362145,318,943 - 45,470,902 (+)NCBINCBI36hg18NCBI36
Build 342145,318,942 - 45,470,902NCBI
Celera2131,601,137 - 31,754,043 (+)NCBI
Cytogenetic Map21q22.3NCBI
HuRef2131,920,569 - 32,018,419 (+)NCBIHuRef
CHM1_12146,055,410 - 46,207,429 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on ADARB1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 732582
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2020-09-29
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.