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Gene: Ank3 (ankyrin 3) Rattus norvegicus
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Symbol: Ank3
Name: ankyrin 3
RGD ID: 620157
Description: Exhibits several functions, including cadherin binding activity; ion channel binding activity; and spectrin binding activity. Involved in several processes, including clustering of voltage-gated sodium channels; positive regulation of protein targeting to membrane; and regulation of ion transport. Localizes to several cellular components, including Z disc; main axon; and spectrin-associated cytoskeleton. Predicted to colocalize with bicellular tight junction. Biomarker of status epilepticus. Human ortholog(s) of this gene implicated in autosomal recessive non-syndromic intellectual disability. Orthologous to human ANK3 (ankyrin 3); INTERACTS WITH (+)-pilocarpine; 2,2',5,5'-tetrachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: ANK-3; ankyrin 3 (G); ankyrin 3, epithelial; ankyrin 3, epithelial isoform g; ankyrin 3, node of Ranvier; ankyrin 3, node of Ranvier (ankyrin G); ankyrin-3; ankyrin-G
Orthologs:
Homo sapiens (human) : ANK3 (ankyrin 3)  HGNC  Alliance
Mus musculus (house mouse) : Ank3 (ankyrin 3, epithelial)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ank3 (ankyrin 3)
Pan paniscus (bonobo/pygmy chimpanzee) : ANK3 (ankyrin 3)
Canis lupus familiaris (dog) : ANK3 (ankyrin 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ank3 (ankyrin 3)
Sus scrofa (pig) : ANK3 (ankyrin 3)
Chlorocebus sabaeus (African green monkey) : ANK3 (ankyrin 3)
Heterocephalus glaber (naked mole-rat) : Ank3 (ankyrin 3)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.02019,948,767 - 20,480,628 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2020,105,047 - 20,480,623 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02022,087,201 - 22,609,939 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42019,328,684 - 19,828,196 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12019,342,749 - 19,991,423 (-)NCBI
Celera2019,989,307 - 20,463,938 (-)NCBICelera
Cytogenetic Map20p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Ank3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 620157
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.