Predicted to enable heparin binding activity; receptor ligand activity; and type 2 fibroblast growth factor receptor binding activity. Involved in several processes, including angiogenesis; response to estradiol; and response to lipopolysaccharide. Acts upstream of or within organ induction. Predicted to be located in several cellular components, including cell surface; extracellular space; and nucleus. Predicted to colocalize with collagen-containing extracellular matrix. Biomarker of hypospadias. Human ortholog(s) of this gene implicated in aplasia of lacrimal and salivary glands and lacrimoauriculodentodigital syndrome 3. Orthologous to human FGF10 (fibroblast growth factor 10); PARTICIPATES IN melanoma pathway; mitogen activated protein kinase signaling pathway; INTERACTS WITH 1,3,5-trinitro-1,3,5-triazinane; 1-[(4-chlorophenyl)-phenylmethyl]-4-methylpiperazine; 17beta-estradiol.
[Chir 99021 co-treated with BMP4 protein co-treated with FGF10 protein co-treated with FGF7 protein co-treated with Tretinoin] results in increased expression of CD68 mRNA more ...
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [FGF10 protein inhibits the reaction [Asbestos results in increased activity of CASP9 protein]] more ...
[Chir 99021 co-treated with BMP4 protein co-treated with FGF10 protein co-treated with FGF7 protein co-treated with Tretinoin] results in increased expression of CD68 mRNA more ...
Colforsin inhibits the reaction [FGF10 protein results in increased phosphorylation of MAPK1 protein] and Colforsin inhibits the reaction [FGF10 protein results in increased phosphorylation of MAPK3 protein]
[Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in decreased expression of FGF10 mRNA and [Air Pollutants results in increased abundance of Ozone] which results in decreased expression of FGF10 mRNA
Adult Neurogenesis in the Female Mouse Hypothalamus: Estradiol and High-Fat Diet Alter the Generation of Newborn Neurons Expressing Estrogen Receptor α.