Fgf10 (fibroblast growth factor 10) - Rat Genome Database

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Gene: Fgf10 (fibroblast growth factor 10) Rattus norvegicus
Analyze
Symbol: Fgf10
Name: fibroblast growth factor 10
RGD ID: 2606
Description: Predicted to enable heparin binding activity; receptor ligand activity; and type 2 fibroblast growth factor receptor binding activity. Involved in several processes, including angiogenesis; response to estradiol; and response to lipopolysaccharide. Predicted to be located in cell surface; nucleus; and plasma membrane. Predicted to be active in cytoplasm and extracellular space. Predicted to colocalize with collagen-containing extracellular matrix. Biomarker of hypospadias. Human ortholog(s) of this gene implicated in LADD syndrome and aplasia of lacrimal and salivary glands. Orthologous to human FGF10 (fibroblast growth factor 10); PARTICIPATES IN melanoma pathway; mitogen activated protein kinase signaling pathway; INTERACTS WITH 1,3,5-trinitro-1,3,5-triazinane; 1-[(4-chlorophenyl)-phenylmethyl]-4-methylpiperazine; 17beta-estradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: FGF-10; Fgf5a; fibroblast growth factor 5a
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2250,801,897 - 50,875,428 (+)NCBI
Rnor_6.0 Ensembl251,672,722 - 51,750,369 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0251,673,480 - 51,747,533 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0270,046,331 - 70,120,384 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4250,866,799 - 50,940,319 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1250,795,031 - 50,868,552 (+)NCBI
Celera246,463,913 - 46,537,376 (+)NCBICelera
Cytogenetic Map2q15NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
actin cytoskeleton reorganization  (ISO)
angiogenesis  (IEP)
animal organ formation  (ISO)
animal organ morphogenesis  (IBA,ISO)
blood vessel morphogenesis  (ISO)
blood vessel remodeling  (ISO)
branch elongation involved in salivary gland morphogenesis  (ISO)
branching involved in salivary gland morphogenesis  (ISO)
branching morphogenesis of an epithelial tube  (ISO)
bronchiole morphogenesis  (ISO)
bud elongation involved in lung branching  (ISO)
bud outgrowth involved in lung branching  (ISO)
cell differentiation  (IBA,IEP)
cell-cell signaling  (ISO)
chemotaxis  (ISO)
determination of left/right symmetry  (ISO)
digestive tract development  (ISO)
embryonic camera-type eye development  (ISO)
embryonic digestive tract development  (ISO)
embryonic digestive tract morphogenesis  (ISO)
embryonic genitalia morphogenesis  (ISO)
embryonic pattern specification  (ISO)
epidermis development  (ISO)
epidermis morphogenesis  (ISO)
epithelial cell differentiation  (ISO)
epithelial cell proliferation  (ISO)
epithelial cell proliferation involved in salivary gland morphogenesis  (ISO)
epithelial tube branching involved in lung morphogenesis  (ISO)
ERK1 and ERK2 cascade  (ISO)
establishment of mitotic spindle orientation  (ISO)
female genitalia morphogenesis  (ISO)
fibroblast growth factor receptor signaling pathway  (IBA,TAS)
fibroblast growth factor receptor signaling pathway involved in mammary gland specification  (IBA,ISO)
hair follicle morphogenesis  (ISO)
Harderian gland development  (ISO)
induction of positive chemotaxis  (ISO)
inner ear morphogenesis  (ISO)
lacrimal gland development  (ISO)
limb bud formation  (ISO)
limb development  (IBA,ISO)
limb morphogenesis  (ISO)
lung alveolus development  (ISO)
lung development  (ISO)
lung epithelium development  (ISO)
lung morphogenesis  (ISO)
lung proximal/distal axis specification  (ISO)
lung saccule development  (ISO)
male genitalia morphogenesis  (ISO)
mammary gland bud formation  (ISO)
mammary gland specification  (ISO)
mesenchymal cell differentiation involved in lung development  (ISO)
mesenchymal-epithelial cell signaling involved in lung development  (ISO)
mesonephros development  (ISO)
metanephros development  (ISO)
metanephros morphogenesis  (ISO)
muscle cell fate commitment  (ISO)
negative regulation of cell differentiation  (ISO)
negative regulation of cell population proliferation  (ISO)
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand  (ISO)
odontogenesis of dentin-containing tooth  (ISO)
organ growth  (ISO)
organ induction  (IDA,ISO)
otic vesicle formation  (ISO)
pancreas development  (ISO)
pituitary gland development  (ISO)
positive chemotaxis  (IBA,ISO)
positive regulation of ATPase activity  (ISO)
positive regulation of canonical Wnt signaling pathway  (IBA,ISO)
positive regulation of cell population proliferation  (IBA,ISO)
positive regulation of DNA repair  (ISO)
positive regulation of epithelial cell migration  (IBA,ISO)
positive regulation of epithelial cell proliferation  (IBA,ISO)
positive regulation of ERK1 and ERK2 cascade  (IBA,ISO)
positive regulation of fibroblast proliferation  (ISO)
positive regulation of G1/S transition of mitotic cell cycle  (ISO)
positive regulation of gene expression  (IBA)
positive regulation of hair follicle cell proliferation  (ISO)
positive regulation of keratinocyte migration  (ISO)
positive regulation of keratinocyte proliferation  (ISO)
positive regulation of lymphocyte proliferation  (ISO)
positive regulation of MAPK cascade  (ISO)
positive regulation of mitotic cell cycle  (ISO)
positive regulation of Notch signaling pathway  (ISO)
positive regulation of peptidyl-tyrosine phosphorylation  (ISO)
positive regulation of protein phosphorylation  (IBA)
positive regulation of Ras protein signal transduction  (ISO)
positive regulation of transcription by RNA polymerase II  (ISO)
positive regulation of transcription, DNA-templated  (ISO)
positive regulation of urothelial cell proliferation  (ISO,ISS)
positive regulation of vascular endothelial growth factor receptor signaling pathway  (ISO)
positive regulation of white fat cell proliferation  (ISO)
positive regulation of Wnt signaling pathway  (ISO)
prostatic bud formation  (ISO)
protein localization to cell surface  (ISO)
radial glial cell differentiation  (ISO)
regulation of activin receptor signaling pathway  (ISO)
regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling  (ISO)
regulation of cell cycle  (ISO)
regulation of cell migration  (IBA)
regulation of gene expression  (ISO)
regulation of saliva secretion  (ISO)
regulation of smoothened signaling pathway  (ISO)
respiratory system development  (ISO)
response to estradiol  (IEP)
response to lipopolysaccharide  (IEP)
response to organic cyclic compound  (IEP)
salivary gland development  (ISO)
salivary gland morphogenesis  (ISO)
secretion by lung epithelial cell involved in lung growth  (IBA,ISO)
semicircular canal fusion  (ISO)
semicircular canal morphogenesis  (ISO)
smooth muscle cell differentiation  (ISO)
somatic stem cell population maintenance  (ISO)
spleen development  (ISO)
submandibular salivary gland formation  (ISO)
tear secretion  (ISO)
thymus development  (ISO)
thyroid gland development  (ISO)
tissue regeneration  (IEP)
type II pneumocyte differentiation  (ISO)
urothelial cell proliferation  (ISO)
white fat cell differentiation  (ISO)
wound healing  (IBA,ISO)

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
1. Bless EP, etal., eNeuro. 2016 Sep 22;3(4). pii: eN-NWR-0027-16. doi: 10.1523/ENEURO.0027-16.2016. eCollection 2016 Jul-Aug.
2. Gambichler T, etal., BMC Dermatol. 2002 Apr 12;2:6. doi: 10.1186/1471-5945-2-6.
3. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. GOA data from the GO Consortium
5. Govindarajan V, etal., Dev Biol. 2000 Sep 1;225(1):188-200.
6. Hamady ZZ, Ann R Coll Surg Engl. 2013 May;95(4):235-40. doi: 10.1308/003588413X13511609958217.
7. Hamady ZZ, etal., Gut. 2010 Apr;59(4):461-9. doi: 10.1136/gut.2008.176131. Epub 2009 Sep 7.
8. Hertzler-Schaefer K, etal., Cell Rep. 2014 Mar 13;6(5):818-26. doi: 10.1016/j.celrep.2014.01.045. Epub 2014 Feb 27.
9. Huang L, etal., Dev Biol. 2005 Feb 15;278(2):396-414.
10. Imaoka T, etal., J Radiat Res (Tokyo). 2008 Apr 16;.
11. Ishiwata T, etal., Exp Mol Pathol 2002 Dec;73(3):181-90.
12. Kelly RG, etal., Dev Cell 2001 Sep;1(3):435-40.
13. MGD data from the GO Consortium
14. Miceli R, etal., J Pharmacol Exp Ther. 1999 Jul;290(1):464-71.
15. Muratore CS, etal., J Surg Res. 2009 Aug;155(2):225-30. Epub 2008 Aug 9.
16. NCBI rat LocusLink and RefSeq merged data July 26, 2002
17. OMIM Disease Annotation Pipeline
18. Pipeline to import KEGG annotations from KEGG into RGD
19. Quantius J, etal., PLoS Pathog. 2016 Jun 20;12(6):e1005544. doi: 10.1371/journal.ppat.1005544. eCollection 2016 Jun.
20. RGD automated data pipeline
21. RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
22. RGD automated import pipeline for gene-chemical interactions
23. RGD comprehensive gene curation
24. Sautter NB, etal., Int J Pediatr Otorhinolaryngol. 2011 Nov;75(11):1368-71. doi: 10.1016/j.ijporl.2011.07.026. Epub 2011 Sep 1.
25. Sekine K, etal., Nat Genet 1999 Jan;21(1):138-41.
26. Soler PM, etal., Wound Repair Regen. 1999 May-Jun;7(3):172-8. doi: 10.1046/j.1524-475x.1999.00172.x.
27. Suzuki K, etal., FEBS Lett 2000 Sep 8;481(1):53-6.
28. Wu J, etal., J Biol Chem. 2019 Oct 11;294(41):15052-15067. doi: 10.1074/jbc.RA119.007404. Epub 2019 Aug 20.
29. Yamamoto S, etal., Biochim Biophys Acta 1998 May 29;1398(1):38-41.
30. Yamasaki M, etal., J Biol Chem 1996 Jul 5;271(27):15918-21.
31. Zhu YJ, etal., Toxicology. 2009 Jun 16;260(1-3):120-5. Epub 2009 Apr 5.
Additional References at PubMed
PMID:9393979   PMID:9428423   PMID:9740653   PMID:9784490   PMID:10541313   PMID:10804187   PMID:10821755   PMID:11062007   PMID:11287183   PMID:11782400   PMID:11880361   PMID:11896977  
PMID:11923311   PMID:11959839   PMID:12004962   PMID:12615071   PMID:12804770   PMID:12810586   PMID:12837279   PMID:12861530   PMID:12941620   PMID:14530295   PMID:14604677   PMID:14623822  
PMID:14651921   PMID:14697353   PMID:14726452   PMID:14975937   PMID:15017552   PMID:15130516   PMID:15199404   PMID:15234214   PMID:15329346   PMID:15531758   PMID:15654336   PMID:15690149  
PMID:15765517   PMID:15800000   PMID:15843416   PMID:15958512   PMID:15972105   PMID:16086254   PMID:16141225   PMID:16169547   PMID:16308329   PMID:16324690   PMID:16375885   PMID:16597614  
PMID:16618415   PMID:16691564   PMID:16720875   PMID:16956603   PMID:16989802   PMID:17000704   PMID:17071719   PMID:17188682   PMID:17202188   PMID:17213838   PMID:17218409   PMID:17394208  
PMID:17449030   PMID:17471512   PMID:17500053   PMID:17522155   PMID:17560563   PMID:17601531   PMID:17923768   PMID:17959718   PMID:17969154   PMID:18421016   PMID:18437684   PMID:18559345  
PMID:19102732   PMID:19152659   PMID:19224135   PMID:19607792   PMID:20705941   PMID:21136143   PMID:21147086   PMID:21764747   PMID:22261751   PMID:23143078   PMID:26514922   PMID:26869337  
PMID:29758198   PMID:33577857  


Genomics

Comparative Map Data
Fgf10
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2250,801,897 - 50,875,428 (+)NCBI
Rnor_6.0 Ensembl251,672,722 - 51,750,369 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0251,673,480 - 51,747,533 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0270,046,331 - 70,120,384 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4250,866,799 - 50,940,319 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1250,795,031 - 50,868,552 (+)NCBI
Celera246,463,913 - 46,537,376 (+)NCBICelera
Cytogenetic Map2q15NCBI
FGF10
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl544,300,247 - 44,389,706 (-)EnsemblGRCh38hg38GRCh38
GRCh38544,300,247 - 44,389,706 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37544,300,349 - 44,389,522 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36544,340,854 - 44,424,541 (-)NCBINCBI36hg18NCBI36
Build 34544,340,853 - 44,424,541NCBI
Celera544,197,375 - 44,281,044 (-)NCBI
Cytogenetic Map5p12NCBI
HuRef544,258,055 - 44,341,703 (-)NCBIHuRef
CHM1_1544,306,497 - 44,390,196 (-)NCBICHM1_1
Fgf10
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3913118,851,235 - 118,929,109 (+)NCBIGRCm39mm39
GRCm39 Ensembl13118,806,327 - 118,928,651 (+)Ensembl
GRCm3813118,714,699 - 118,792,573 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl13118,669,791 - 118,792,115 (+)EnsemblGRCm38mm10GRCm38
MGSCv3713119,503,506 - 119,581,380 (+)NCBIGRCm37mm9NCBIm37
MGSCv3613119,833,907 - 119,910,988 (+)NCBImm8
Celera13123,161,950 - 123,245,519 (+)NCBICelera
Cytogenetic Map13D2.3NCBI
cM Map1367.14NCBI
Fgf10
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544618,163,117 - 18,245,199 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495544618,163,117 - 18,244,840 (+)NCBIChiLan1.0ChiLan1.0
FGF10
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1571,028,324 - 71,111,713 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl571,028,187 - 71,111,706 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0565,979,443 - 66,069,314 (+)NCBIMhudiblu_PPA_v0panPan3
FGF10
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1465,851,130 - 65,930,944 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl465,851,069 - 65,928,192 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha465,597,673 - 65,676,839 (+)NCBI
ROS_Cfam_1.0466,343,407 - 66,423,104 (+)NCBI
UMICH_Zoey_3.1466,096,317 - 66,176,025 (+)NCBI
UNSW_CanFamBas_1.0466,218,509 - 66,297,862 (+)NCBI
UU_Cfam_GSD_1.0466,768,760 - 66,848,396 (+)NCBI
Fgf10
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213209,177,124 - 209,259,405 (+)NCBI
SpeTri2.0NW_00493648018,114,231 - 18,195,884 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FGF10
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1628,695,469 - 28,777,541 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11628,695,465 - 28,779,953 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21630,234,658 - 30,317,449 (-)NCBISscrofa10.2Sscrofa10.2susScr3
FGF10
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1443,080,387 - 43,163,355 (-)NCBI
ChlSab1.1 Ensembl443,081,831 - 43,163,432 (-)Ensembl
Vero_WHO_p1.0NW_02366607133,710,353 - 33,794,576 (-)NCBI
Fgf10
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462475910,904,626 - 10,983,509 (+)NCBI

Position Markers
PMC26870P2  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2250,801,966 - 50,802,211 (+)MAPPER
Rnor_6.0251,673,550 - 51,673,794NCBIRnor6.0
Rnor_5.0270,046,401 - 70,046,645UniSTSRnor5.0
RGSC_v3.4250,866,869 - 50,867,113UniSTSRGSC3.4
Celera246,463,983 - 46,464,227UniSTS
Cytogenetic Map2q15-q16UniSTS
G16001  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2250,801,927 - 50,802,169 (+)MAPPER
Rnor_6.0251,673,511 - 51,673,752NCBIRnor6.0
Rnor_5.0270,046,362 - 70,046,603UniSTSRnor5.0
RGSC_v3.4250,866,830 - 50,867,071UniSTSRGSC3.4
Celera246,463,944 - 46,464,185UniSTS
Cytogenetic Map2q15-q16UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
61355Bp36Blood pressure QTL 362.9blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)23127638105149020Rat
738012Anxrr3Anxiety related response QTL 33.8exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)2789360052893600Rat
1578671Bmd10Bone mineral density QTL 105.4femur mineral mass (VT:0010011)cortical volumetric bone mineral density (CMO:0001730)2944467968866454Rat
10755430Coatc6Coat color QTL 60.02576coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)21055527555555275Rat
731184Mamtr4Mammary tumor resistance QTL 40.0003mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)21423783059237830Rat
10755499Bp389Blood pressure QTL 3892.61arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)216679272245624402Rat
1357990Ael1Aortic elastin QTL 13.10.00091aorta elastin amount (VT:0003905)aortic elastin21901646564016465Rat
731167Glom4Glomerulus QTL 42.40.0082kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)22027698165276981Rat
2300168Bmd47Bone mineral density QTL 476.60.0001femur mineral mass (VT:0010011)bone mineral density (CMO:0001226)22064137165641371Rat
7387318Stl32Serum triglyceride level QTL 323.20.0003blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)22261295267612952Rat
10402051Gdil2Gastrointestinal dilation QTL 2enteric ganglion morphology trait (VT:0001045)length of intestine affected by colonic aganglionosis to total length of colon ratio (CMO:0001836)22328064775687607Rat
1302794Stl27Serum triglyceride level QTL 274.40.0001blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)223837491149614623Rat
1358894Kidm24Kidney mass QTL 244.03kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)223837491169852800Rat
1358899Kidm23Kidney mass QTL 233.88kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)223837491169852800Rat
1358901Cm38Cardiac mass QTL 382heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)223837491169852800Rat
1358904Cm39Cardiac mass QTL 392.26heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)223837491169852800Rat
1358910Kidm27Kidney mass QTL 275.77kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)223837491169852800Rat
1358911Kidm28Kidney mass QTL 285.42kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)223837491169852800Rat
1358913Cm41Cardiac mass QTL 412.73heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)223837491218957222Rat
1358917Cm42Cardiac mass QTL 422.82heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)223837491218957222Rat
1358887Bw50Body weight QTL 502.39body mass (VT:0001259)body weight (CMO:0000012)223837719169852670Rat
1358908Bw49Body weight QTL 493.36body mass (VT:0001259)body weight (CMO:0000012)223837719169852670Rat
1354617Bp240Blood pressure QTL 2404arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)22618609783819822Rat
1354617Bp240Blood pressure QTL 2404arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)22618609783819822Rat
1354617Bp240Blood pressure QTL 2404arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)22618609783819822Rat
1354603Bp243Blood pressure QTL 2433.9arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)226186097135654963Rat
2290453Scl55Serum cholesterol level QTL 552.83blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)226186097142053534Rat
12879841Cm87Cardiac mass QTL 870.026heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)227161361148295267Rat
12879842Cm88Cardiac mass QTL 880.042heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)227161361148295267Rat
12879843Am3Aortic mass QTL 30.016aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)227161361148295267Rat
12879844Kidm62Kidney mass QTL 620.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)227161361148295267Rat
9590095Sffal3Serum free fatty acids level QTL 36.780.001blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)22776030172760301Rat
1300160Hrtrt3Heart rate QTL 33.62heart pumping trait (VT:2000009)absolute change in heart rate (CMO:0000534)22872786752507805Rat
10755434Coatc7Coat color QTL 70.04794coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)23127237976272379Rat
61371Edpm1Estrogen-dependent pituitary mass QTL 140.05pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)23408817591101903Rat
10755436Coatc8Coat color QTL 80.02431coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)23513320280133202Rat
2306903Bp336Blood pressure QTL 3360.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)236245223112175725Rat
70174BpQTLCluster2Blood pressure QTL cluster 24.24arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)240171834105089682Rat
70174BpQTLCluster2Blood pressure QTL cluster 24.24arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)240171834105089682Rat
70174BpQTLCluster2Blood pressure QTL cluster 24.24arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)240171834105089682Rat
70174BpQTLCluster2Blood pressure QTL cluster 24.24arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)240171834105089682Rat
70174BpQTLCluster2Blood pressure QTL cluster 24.24arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)240171834105089682Rat
12879863Bp402Blood pressure QTL 4020.003arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)24106343956736627Rat
1300155Bp174Blood pressure QTL 1744.09arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)24277691662238534Rat
2293835Kiddil5Kidney dilation QTL 53.8kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)242776916169852800Rat
2293843Kiddil6Kidney dilation QTL 63.1kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)242776916195645082Rat
1298085Bp165Blood pressure QTL 1650.0006arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)242776916217498710Rat
1298074Bp164Blood pressure QTL 1640.003arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)242776916217498710Rat
61467Bp14Blood pressure QTL 142.2arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)243133606217498545Rat
61467Bp14Blood pressure QTL 142.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)243133606217498545Rat
2293676Bmd19Bone mineral density QTL 1910.70.0001femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)243141290114164944Rat
2293682Bmd24Bone mineral density QTL 248.90.0001femur mineral mass (VT:0010011)cortical volumetric bone mineral density (CMO:0001730)243141290114164944Rat
2293671Bss44Bone structure and strength QTL 4410.970.0001lumbar vertebra morphology trait (VT:0010494)lumbar vertebra cortical cross-sectional area (CMO:0001690)243141290154583160Rat
631208Bw1Body weight QTL15.09mesenteric fat pad mass (VT:0010427)mesenteric fat pad weight to body weight ratio (CMO:0000654)24314978885642672Rat
1354601Slep1Serum leptin concentration QTL 15.39blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)243149788198704485Rat
631266Bp132Blood pressure QTL 1320.0005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)246537589217498710Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:31
Count of miRNA genes:28
Interacting mature miRNAs:31
Transcripts:ENSRNOT00000016485
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 4 4 4 6 6 1
Low 2 41 20 6 11 6 5 6 66 27 26 10 5
Below cutoff 1 2 12 10 8 10 3 5 8 2 5 3

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000016485   ⟹   ENSRNOP00000016485
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl251,672,722 - 51,750,369 (+)Ensembl
RefSeq Acc Id: NM_012951   ⟹   NP_037083
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2250,801,897 - 50,875,428 (+)NCBI
Rnor_6.0251,673,480 - 51,747,533 (+)NCBI
Rnor_5.0270,046,331 - 70,120,384 (+)NCBI
RGSC_v3.4250,866,799 - 50,940,319 (+)RGD
Celera246,463,913 - 46,537,376 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_037083 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein BAA11468 (Get FASTA)   NCBI Sequence Viewer  
  EDM10410 (Get FASTA)   NCBI Sequence Viewer  
  P70492 (Get FASTA)   NCBI Sequence Viewer  
  VDK10958 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_037083   ⟸   NM_012951
- Peptide Label: precursor
- UniProtKB: P70492 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSRNOP00000016485   ⟸   ENSRNOT00000016485

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13691155
Promoter ID:EPDNEW_R1679
Type:single initiation site
Name:Fgf10_1
Description:fibroblast growth factor 10
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0251,673,115 - 51,673,175EPDNEW

Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2606 AgrOrtholog
Ensembl Genes ENSRNOG00000012278 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSRNOP00000016485 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000016485 ENTREZGENE, UniProtKB/Swiss-Prot
InterPro FGF10 UniProtKB/Swiss-Prot
  Fibroblast_GF_fam UniProtKB/Swiss-Prot
  IL1/FGF UniProtKB/Swiss-Prot
KEGG Report rno:25443 UniProtKB/Swiss-Prot
NCBI Gene 25443 ENTREZGENE
PANTHER PTHR11486 UniProtKB/Swiss-Prot
  PTHR11486:SF21 UniProtKB/Swiss-Prot
Pfam FGF UniProtKB/Swiss-Prot
PhenoGen Fgf10 PhenoGen
PRINTS HBGFFGF UniProtKB/Swiss-Prot
PROSITE HBGF_FGF UniProtKB/Swiss-Prot
SMART FGF UniProtKB/Swiss-Prot
Superfamily-SCOP SSF50353 UniProtKB/Swiss-Prot
UniProt FGF10_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2002-06-10 Fgf10  fibroblast growth factor 10      Name updated 70584 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_disease expressed in vascular smooth muscle cells in the pancreas after L-arginine induced pancreatitis 727503
gene_product member of the fibroblast growth factor (FGF) family 69832
gene_protein 215 amino acids; approximately 24 kDa 69832