Fgf10 (fibroblast growth factor 10)

Gene: Fgf10 (fibroblast growth factor 10) Rattus norvegicus

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Symbol:

Fgf10

Name:

fibroblast growth factor 10

Description:

Predicted to have several functions, including heparin binding activity and signaling receptor binding activity; involved in several processes, including angiogenesis, cell differentiation, and organ induction; predicted to colocalize with the collagen-containing extracellular matrix; biomarker of hypospadias; orthologous to human FGF10 (fibroblast growth factor 10); PARTICIPATES IN melanoma pathway; mitogen activated protein kinase signaling pathway; INTERACTS WITH 1,3,5-trinitro-1,3,5-triazinane; 1-[(4-chlorophenyl)-phenylmethyl]-4-methylpiperazine; 17beta-estradiol.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Also known as:

FGF-10

Orthologs:

Homo sapiens (human) : FGF10 (fibroblast growth factor 10) HGNC Alliance
Mus musculus (house mouse) : Fgf10 (fibroblast growth factor 10) MGI Alliance
Chinchilla lanigera (long-tailed chinchilla) : Fgf10 (fibroblast growth factor 10)
Pan paniscus (bonobo/pygmy chimpanzee) : FGF10 (fibroblast growth factor 10)
Canis lupus familiaris (dog) : FGF10 (fibroblast growth factor 10)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fgf10 (fibroblast growth factor 10)
Sus scrofa (pig) : FGF10 (fibroblast growth factor 10)

more info ...

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	FGF10 (fibroblast growth factor 10)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Fgf10 (fibroblast growth factor 10)	HGNC	Treefam, EggNOG, OrthoMCL, NCBI, OMA, HomoloGene, Inparanoid, Panther, PhylomeDB, OrthoDB, Ensembl
Chinchilla lanigera (long-tailed chinchilla):	Fgf10 (fibroblast growth factor 10)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	FGF10 (fibroblast growth factor 10)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	FGF10 (fibroblast growth factor 10)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Fgf10 (fibroblast growth factor 10)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	FGF10 (fibroblast growth factor 10)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Mus musculus (house mouse):	Fgf10 (fibroblast growth factor 10)	Alliance	DIOPT (Ensembl Compara, Hieranoid, InParanoid, OMA, OrthoFinder, OrthoInspector, PANTHER, PhylomeDB, TreeFam)
Homo sapiens (human):	FGF10 (fibroblast growth factor 10)	Alliance	DIOPT (Ensembl Compara, HGNC, Hieranoid, InParanoid, OMA, OrthoFinder, OrthoInspector, PANTHER, PhylomeDB, TreeFam)
Danio rerio (zebrafish):	fgf10a (fibroblast growth factor 10a)	Alliance	DIOPT (Ensembl Compara, Hieranoid, InParanoid, OrthoFinder, OrthoInspector, PANTHER, PhylomeDB, TreeFam)
Danio rerio (zebrafish):	fgf10b (fibroblast growth factor 10b)	Alliance	DIOPT (Ensembl Compara, Hieranoid, OMA, OrthoInspector, PANTHER, PhylomeDB, TreeFam)

Latest Assembly:

Rnor_6.0 - RGSC Genome Assembly v6.0

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rnor_6.0	2	51,673,480 - 51,747,533 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	2	70,046,331 - 70,120,384 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	2	50,866,799 - 50,940,319 (+)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	2	50,795,031 - 50,868,552 (+)	NCBI
Celera	2	46,463,913 - 46,537,376 (+)	NCBI		Celera
Cytogenetic Map	2	q15	NCBI

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Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links

Nomenclature History

RGD Curation Notes

More on Fgf10
	Alliance Gene
	NCBI Gene
	Ensembl Gene
	JBrowse: rn5 rn6
	NCBI Genome Data Viewer

RGD Object Information
RGD ID:	2606
Created:	2000-05-25
Species:	Rattus norvegicus
Last Modified:	2019-05-28
Status:	ACTIVE

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.

Functional Annotation unavailable	Annotation Distribution unavailable	Genomic Variants unavailble for Mouse Genomic Variants unavailable
Functional Annotation	Annotation Distribution	Genomic Variants

Protein-Protein Interactions unavailable	Genome Viewer unavailable	Damaging Variants unavailble for Mouse Damaging Variants unavailable
Protein-Protein Interactions	Genome Viewer	Damaging Variants

Annotation Comparison unavailable	OLGA unavailable
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Gene Enrichment unavailable
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Imported Annotations - ClinVar

Imported Annotations - CTD

Imported Annotations - MGI

Imported Annotations - OMIM

Imported Annotations - KEGG (archival)