Ltf (lactotransferrin) - Rat Genome Database

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Gene: Ltf (lactotransferrin) Rattus norvegicus
Symbol: Ltf
Name: lactotransferrin
RGD ID: 1305445
Description: Predicted to enable several functions, including cysteine-type endopeptidase inhibitor activity; heparin binding activity; and lipopolysaccharide binding activity. Predicted to be involved in several processes, including defense response to other organism; positive regulation of cell population proliferation; and regulation of signal transduction. Predicted to be located in cell surface and specific granule. Predicted to be part of protein-containing complex. Predicted to be active in endosome; extracellular space; and plasma membrane. Human ortholog(s) of this gene implicated in candidiasis; lung non-small cell carcinoma; and renal cell carcinoma. Orthologous to human LTF (lactotransferrin); INTERACTS WITH 17alpha-ethynylestradiol; 3,3',4,4',5-pentachlorobiphenyl; apigenin.
Type: protein-coding
Previously known as: lactoferrin
RGD Orthologs
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Rat AssemblyChrPosition (strand)SourceGenome Browsers
mRatBN7.28110,999,948 - 111,022,795 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl8110,999,948 - 111,022,795 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx8116,614,671 - 116,637,494 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.08114,813,884 - 114,836,711 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.08112,656,706 - 112,679,539 (+)NCBIRnor_WKY
Rnor_6.08119,290,416 - 119,313,261 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8119,290,416 - 119,313,261 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08118,632,730 - 118,655,575 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48115,417,764 - 115,440,609 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.18115,437,256 - 115,458,062 (+)NCBI
Celera8110,282,264 - 110,305,105 (+)NCBICelera
Cytogenetic Map8q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(S)-nicotine  (ISO)
1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane  (ISO)
1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane  (ISO)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
3,3',5,5'-tetrabromobisphenol A  (ISO)
4-hydroxy-17beta-estradiol  (ISO)
4-nonylphenol  (ISO)
4-octylphenol  (ISO)
afimoxifene  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
aluminium oxide  (ISO)
apigenin  (EXP)
Aroclor 1254  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
atrazine  (ISO)
atropine  (ISO)
azathioprine  (ISO)
beclomethasone  (ISO)
benzo[a]pyrene  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bis(2-ethylhexyl) phthalate  (EXP)
bisphenol A  (EXP,ISO)
budesonide  (ISO)
cadmium atom  (ISO)
calcitriol  (ISO)
capsaicin  (ISO)
carbon nanotube  (ISO)
cerium trichloride  (ISO)
chlordecone  (ISO)
chlorpyrifos  (ISO)
cisplatin  (ISO)
cyclophosphamide  (ISO)
cyclosporin A  (ISO)
dexamethasone  (EXP)
diamminedichloroplatinum  (ISO)
diazinon  (ISO)
diethylstilbestrol  (ISO)
disodium selenite  (ISO)
enzyme inhibitor  (ISO)
epoxiconazole  (ISO)
fenarimol  (EXP)
fonofos  (ISO)
fulvestrant  (ISO)
genistein  (EXP,ISO)
genistein 7-O-beta-D-glucoside  (ISO)
irinotecan  (ISO)
lipopolysaccharide  (ISO)
lipoteichoic acid  (ISO)
MeIQx  (EXP)
methotrexate  (ISO)
methoxychlor  (ISO)
myricetin  (EXP)
N,N-dimethylformamide  (ISO)
naloxone  (EXP)
nickel atom  (ISO)
nicotine  (ISO)
nitric oxide  (EXP)
Nonylphenol  (ISO)
ozone  (ISO)
paracetamol  (ISO)
parathion  (ISO)
perfluorooctanoic acid  (ISO)
phloretin  (EXP)
phosphatidylcholine  (ISO)
phytosterols  (ISO)
prednisolone  (ISO)
progesterone  (ISO)
pyridaben  (ISO)
reactive oxygen species  (EXP)
senecionine  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenite  (ISO)
sodium dodecyl sulfate  (ISO)
sodium fluoride  (ISO)
sulforaphane  (ISO)
tacrolimus hydrate  (ISO)
tamoxifen  (EXP,ISO)
terbufos  (ISO)
thalidomide  (ISO)
theophylline  (ISO)
titanium dioxide  (ISO)
transplatin  (ISO)
tremolite asbestos  (ISO)
tributylstannane  (ISO)
tropan-3alpha-yl 3-hydroxy-2-phenylpropanoate  (ISO)
tungsten  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
antibacterial humoral response  (IBA,ISO)
antifungal humoral response  (ISO)
antimicrobial humoral immune response mediated by antimicrobial peptide  (ISO)
biological_process  (ND)
bone morphogenesis  (ISO)
defense response to Gram-negative bacterium  (ISO)
defense response to Gram-positive bacterium  (ISO)
disruption of membrane integrity in another organism  (ISO)
innate immune response  (ISO)
innate immune response in mucosa  (ISO)
iron ion transport  (IBA)
killing of cells of another organism  (ISO)
negative regulation by host of viral process  (ISO)
negative regulation of ATP-dependent activity  (ISO)
negative regulation of cysteine-type endopeptidase activity  (ISO)
negative regulation of lipopolysaccharide-mediated signaling pathway  (ISO)
negative regulation of membrane potential  (ISO)
negative regulation of single-species biofilm formation in or on host organism  (ISO)
negative regulation of viral genome replication  (ISO)
negative regulation of viral process  (ISO)
positive regulation of chondrocyte proliferation  (ISO)
positive regulation of I-kappaB kinase/NF-kappaB signaling  (ISO)
positive regulation of NF-kappaB transcription factor activity  (ISO)
positive regulation of osteoblast differentiation  (ISO)
positive regulation of osteoblast proliferation  (ISO)
positive regulation of protein serine/threonine kinase activity  (ISO)
positive regulation of toll-like receptor 4 signaling pathway  (ISO)
regulation of cytokine production  (ISO)
regulation of tumor necrosis factor production  (ISO)
retina homeostasis  (ISO)

Cellular Component


References - curated
# Reference Title Reference Citation
1. Influence of lactoferrin feeding and injection against systemic staphylococcal infections in mice. Bhimani RS, etal., J Appl Microbiol. 1999 Jan;86(1):135-44.
2. A randomized, double-blind, placebo-controlled, phase II study of oral talactoferrin in combination with carboplatin and paclitaxel in previously untreated locally advanced or metastatic non-small cell lung cancer. Digumarti R, etal., J Thorac Oncol. 2011 Jun;6(6):1098-103. doi: 10.1097/JTO.0b013e3182156250.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. Lung injury after ozone exposure is iron dependent. Ghio AJ, etal., Am J Physiol Lung Cell Mol Physiol. 2007 Jan;292(1):L134-43. Epub 2006 Aug 11.
5. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
6. A phase 2 randomized, double-blind, placebo-controlled study of the safety and efficacy of talactoferrin in patients with severe sepsis. Guntupalli K, etal., Crit Care Med. 2013 Mar;41(3):706-16. doi: 10.1097/CCM.0b013e3182741551.
7. Involvement of protein kinase C in C5a-primed neutrophils for ANCA-mediated activation. Hao J, etal., Mol Immunol. 2013 May;54(1):68-73. doi: 10.1016/j.molimm.2012.10.041. Epub 2012 Nov 28.
8. Human lactoferrin-derived peptide's antifungal activities against disseminated Candida albicans infection. Lupetti A, etal., J Infect Dis. 2007 Nov 1;196(9):1416-24. Epub 2007 Oct 2.
9. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
10. Biliary lactoferrin concentrations are increased in active inflammatory bowel disease: a factor in the pathogenesis of primary sclerosing cholangitis? Pereira SP, etal., Clin Sci (Lond). 1998 Nov;95(5):637-44.
11. GOA pipeline RGD automated data pipeline
12. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
13. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
14. Comprehensive gene review and curation RGD comprehensive gene curation
15. Acute inflammatory proteins constitute the organic matrix of prostatic corpora amylacea and calculi in men with prostate cancer. Sfanos KS, etal., Proc Natl Acad Sci U S A. 2009 Mar 3;106(9):3443-8. doi: 10.1073/pnas.0810473106. Epub 2009 Feb 6.
16. ANCA with specificity for lactoferrin in systemic lupus erythematosus (SLE). Sinico RA, etal., Adv Exp Med Biol. 1993;336:385-7.
Additional References at PubMed
PMID:1599934   PMID:2981589   PMID:9596699   PMID:9727055   PMID:11083624   PMID:11907569   PMID:12037568   PMID:12390874   PMID:12522210   PMID:12788072   PMID:15155221   PMID:15166119  
PMID:15572693   PMID:16502470   PMID:16650524   PMID:17023661   PMID:17567961   PMID:18714013   PMID:19199708   PMID:20345905   PMID:21630459   PMID:22664934   PMID:23376485   PMID:23533145  
PMID:23580065   PMID:24383868   PMID:25193851   PMID:27313089   PMID:34716503  


Comparative Map Data
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
mRatBN7.28110,999,948 - 111,022,795 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl8110,999,948 - 111,022,795 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx8116,614,671 - 116,637,494 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.08114,813,884 - 114,836,711 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.08112,656,706 - 112,679,539 (+)NCBIRnor_WKY
Rnor_6.08119,290,416 - 119,313,261 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8119,290,416 - 119,313,261 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08118,632,730 - 118,655,575 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48115,417,764 - 115,440,609 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.18115,437,256 - 115,458,062 (+)NCBI
Celera8110,282,264 - 110,305,105 (+)NCBICelera
Cytogenetic Map8q32NCBI
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38346,435,645 - 46,485,234 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl346,435,645 - 46,485,234 (-)EnsemblGRCh38hg38GRCh38
GRCh37346,477,136 - 46,526,724 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36346,452,500 - 46,481,399 (-)NCBINCBI36Build 36hg18NCBI36
Build 34346,452,500 - 46,481,399NCBI
Celera346,414,868 - 46,443,775 (-)NCBICelera
Cytogenetic Map3p21.31NCBI
HuRef346,519,882 - 46,548,964 (-)NCBIHuRef
CHM1_1346,427,517 - 46,456,606 (-)NCBICHM1_1
T2T-CHM13v2.0346,451,475 - 46,501,054 (-)NCBIT2T-CHM13v2.0
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm399110,848,360 - 110,871,834 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl9110,848,339 - 110,871,835 (+)EnsemblGRCm39 Ensembl
GRCm389111,019,292 - 111,042,766 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9111,019,271 - 111,042,767 (+)EnsemblGRCm38mm10GRCm38
MGSCv379110,921,796 - 110,945,270 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv369110,864,108 - 110,887,582 (+)NCBIMGSCv36mm8
Celera9110,742,738 - 110,766,162 (+)NCBICelera
Cytogenetic Map9F2NCBI
cM Map960.79NCBI
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
ChiLan1.0 EnsemblNW_00495542025,580,359 - 25,604,331 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542025,580,449 - 25,604,277 (+)NCBIChiLan1.0ChiLan1.0
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
PanPan1.1347,442,440 - 47,471,532 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl347,442,440 - 47,471,532 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0346,337,738 - 46,367,476 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
CanFam3.12042,231,994 - 42,263,202 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2042,231,994 - 42,263,202 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2042,147,994 - 42,179,342 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02042,714,382 - 42,745,648 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2042,698,084 - 42,745,648 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12041,955,622 - 41,986,941 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02042,357,046 - 42,388,364 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02042,637,942 - 42,669,274 (+)NCBIUU_Cfam_GSD_1.0
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
HiC_Itri_2NW_024405118200,795,136 - 200,824,718 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936596344,274 - 373,952 (-)EnsemblSpeTri2.0
SpeTri2.0NW_004936596344,287 - 373,788 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
Sscrofa11.1 Ensembl1329,413,886 - 29,445,739 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11329,413,886 - 29,445,751 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21332,577,743 - 32,609,425 (-)NCBISscrofa10.2Sscrofa10.2susScr3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
ChlSab1.1227,867,332 - 7,896,403 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl227,867,286 - 7,894,521 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041159,254,403 - 159,283,476 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
HetGla_female_1.0 EnsemblNW_00462473074,636,522 - 74,656,886 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473074,636,554 - 74,656,817 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Variants in Ltf
117 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:292
Count of miRNA genes:177
Interacting mature miRNAs:201
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631650Stl6Serum triglyceride level QTL 640.0019blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)810378157112202585Rat
1554321Bmd3Bone mineral density QTL 37.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)840952565123900184Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)846531639119088624Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)846531639119088624Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)absolute change in systolic blood pressure (CMO:0000607)846531639119088624Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)846531639119088624Rat
2303171Bp331Blood pressure QTL 3315.570.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)861290298119084929Rat
631653Bp125Blood pressure QTL 1253.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)866142385111142385Rat
631210Bw3Body weight QTL35.9mesenteric fat pad mass (VT:0010427)mesenteric fat pad weight to body weight ratio (CMO:0000654)869349194112783834Rat
1300171Bp184Blood pressure QTL 1843.66arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)870513503118219066Rat
8694446Bw170Body weight QTL 17012.070.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)871888757116888757Rat
9590292Uminl3Urine mineral level QTL 33.620.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)871888757116888757Rat
8694200Abfw4Abdominal fat weight QTL 49.070.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)871888757116888757Rat
8694392Bw161Body weight QTL 1618.060.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)871888757116888757Rat
1549909Stresp11Stress response QTL 116.830.0019stress-related behavior trait (VT:0010451)number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)873473045118473045Rat
2300181Bmd55Bone mineral density QTL 555.70.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)876468691121468691Rat
61437Cia6Collagen induced arthritis QTL 6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)882460758122812818Rat
2313400Anxrr25Anxiety related response QTL 25aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)889265192114019816Rat
738011Anxrr9Anxiety related response QTL 96.1exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)893535351123900184Rat
1358893Bp263Blood pressure QTL 2635.01arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)893965141123900184Rat
1358903Bp252Blood pressure QTL 25270.0001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)893965141123900184Rat
738014Anxrr15Anxiety related response QTL 153.60.005locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)895718998123900184Rat
2300182Bmd56Bone mineral density QTL 565.4femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)895718998123900184Rat
724539Cm19Cardiac mass QTL 192.6heart mass (VT:0007028)calculated heart weight (CMO:0000073)8100149864120994388Rat


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
Low 1 7 8 21 1
Below cutoff 2 8 15 6 11 6 6 7 9 29 16 10 6


Reference Sequences
RefSeq Acc Id: ENSRNOT00000047752   ⟹   ENSRNOP00000048806
RefSeq Status:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl8110,999,948 - 111,022,795 (+)Ensembl
Rnor_6.0 Ensembl8119,290,416 - 119,313,261 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000095263   ⟹   ENSRNOP00000090955
RefSeq Status:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl8110,999,948 - 111,020,561 (+)Ensembl
RefSeq Acc Id: NM_001106864   ⟹   NP_001100334
Rat AssemblyChrPosition (strand)Source
mRatBN7.28110,999,948 - 111,022,795 (+)NCBI
Rnor_6.08119,290,416 - 119,313,261 (+)NCBI
Rnor_5.08118,632,730 - 118,655,575 (+)NCBI
RGSC_v3.48115,417,764 - 115,440,609 (+)RGD
Celera8110,282,264 - 110,305,105 (+)RGD
Protein Sequences
Protein RefSeqs NP_001100334 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL77040 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_001100334   ⟸   NM_001106864
- Peptide Label: precursor
- UniProtKB: D3ZAB1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000048806   ⟸   ENSRNOT00000047752
RefSeq Acc Id: ENSRNOP00000090955   ⟸   ENSRNOT00000095263
Protein Domains

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZAB1-F1-model_v2 AlphaFold D3ZAB1 1-709 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13696344
Promoter ID:EPDNEW_R6868
Type:single initiation site
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database,
Experiment Methods:Single-end sequencing.
Rat AssemblyChrPosition (strand)Source
Rnor_6.08119,290,416 - 119,290,476EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1305445 AgrOrtholog
BioCyc Gene G2FUF-29037 BioCyc
Ensembl Genes ENSRNOG00000031779 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000048806 ENTREZGENE
  ENSRNOP00000048806.2 UniProtKB/TrEMBL
  ENSRNOP00000090955.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000047752 ENTREZGENE
  ENSRNOT00000047752.3 UniProtKB/TrEMBL
  ENSRNOT00000095263.1 UniProtKB/TrEMBL
InterPro Peptidase_S60 UniProtKB/TrEMBL
  Transferrin UniProtKB/TrEMBL
  Transferrin_Fe_BS UniProtKB/TrEMBL
KEGG Report rno:301034 UniProtKB/TrEMBL
Pfam Transferrin UniProtKB/TrEMBL
PhenoGen Ltf PhenoGen
PIRSF Transferrin UniProtKB/TrEMBL

Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Ltf  lactotransferrin   Ltf_predicted  lactotransferrin (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Ltf_predicted  lactotransferrin (predicted)      Symbol and Name status set to approved 70820 APPROVED