Ltf (lactotransferrin) - Rat Genome Database

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Gene: Ltf (lactotransferrin) Rattus norvegicus
Analyze
Symbol: Ltf
Name: lactotransferrin
RGD ID: 1305445
Description: Predicted to enable several functions, including heparin binding activity; lipopolysaccharide binding activity; and membrane destabilizing activity. Predicted to be involved in several processes, including defense response to symbiont; positive regulation of cell population proliferation; and regulation of signal transduction. Predicted to be located in cell surface and specific granule. Predicted to be part of protein-containing complex. Predicted to be active in endosome; extracellular space; and plasma membrane. Human ortholog(s) of this gene implicated in candidiasis; lung non-small cell carcinoma; and renal cell carcinoma. Orthologous to human LTF (lactotransferrin); INTERACTS WITH 17alpha-ethynylestradiol; 3,3',4,4',5-pentachlorobiphenyl; apigenin.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: lactoferrin
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88119,878,344 - 119,901,189 (+)NCBIGRCr8
mRatBN7.28110,999,948 - 111,022,795 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl8110,999,948 - 111,022,795 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx8116,614,671 - 116,637,494 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.08114,813,884 - 114,836,711 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.08112,656,706 - 112,679,539 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.08119,290,416 - 119,313,261 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8119,290,416 - 119,313,261 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08118,632,730 - 118,655,575 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48115,417,764 - 115,440,609 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.18115,437,256 - 115,458,062 (+)NCBI
Celera8110,282,264 - 110,305,105 (+)NCBICelera
Cytogenetic Map8q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(S)-nicotine  (ISO)
1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane  (ISO)
1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane  (ISO)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
3,3',5,5'-tetrabromobisphenol A  (ISO)
4-hydroxy-17beta-estradiol  (ISO)
4-nonylphenol  (ISO)
4-octylphenol  (ISO)
afimoxifene  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
aluminium oxide  (ISO)
apigenin  (EXP)
Aroclor 1254  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
atrazine  (ISO)
atropine  (ISO)
azathioprine  (ISO)
beclomethasone  (ISO)
benzo[a]pyrene  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bis(2-ethylhexyl) phthalate  (EXP)
bisphenol A  (EXP,ISO)
budesonide  (ISO)
cadmium atom  (ISO)
calcitriol  (ISO)
capsaicin  (ISO)
carbon nanotube  (ISO)
carnosic acid  (ISO)
chlordecone  (ISO)
chlorpyrifos  (ISO)
cisplatin  (ISO)
copper(II) chloride  (ISO)
corosolic acid  (ISO)
cyclophosphamide  (ISO)
cyclosporin A  (ISO)
DDT  (ISO)
dexamethasone  (EXP)
dextran sulfate  (ISO)
diamminedichloroplatinum  (ISO)
diazinon  (ISO)
Dibutyl phosphate  (ISO)
diethylstilbestrol  (ISO)
disodium selenite  (ISO)
doxorubicin  (ISO)
enzyme inhibitor  (ISO)
epoxiconazole  (ISO)
fenarimol  (EXP)
fonofos  (ISO)
fulvestrant  (ISO)
genistein  (EXP,ISO)
genistein 7-O-beta-D-glucoside  (ISO)
irinotecan  (ISO)
lead diacetate  (ISO)
lipopolysaccharide  (ISO)
lipoteichoic acid  (ISO)
MeIQx  (EXP)
mercury atom  (ISO)
mercury(0)  (ISO)
methotrexate  (ISO)
methoxychlor  (ISO)
myricetin  (EXP)
N,N-dimethylformamide  (ISO)
naloxone  (EXP)
nickel atom  (ISO)
nicotine  (ISO)
nitric oxide  (EXP)
Nonylphenol  (ISO)
ozone  (ISO)
paracetamol  (ISO)
parathion  (ISO)
perfluorohexanesulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
phloretin  (EXP)
phosphatidylcholine  (ISO)
phytosterols  (ISO)
prednisolone  (ISO)
progesterone  (ISO)
pyridaben  (ISO)
reactive oxygen species  (EXP)
senecionine  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenite  (ISO)
sodium dodecyl sulfate  (ISO)
sodium fluoride  (ISO)
sulforaphane  (ISO)
tacrolimus hydrate  (ISO)
tamoxifen  (EXP,ISO)
terbufos  (ISO)
thalidomide  (ISO)
theophylline  (ISO)
titanium dioxide  (ISO)
transplatin  (ISO)
tremolite asbestos  (ISO)
tributylstannane  (ISO)
triphenyl phosphate  (ISO)
tropan-3alpha-yl 3-hydroxy-2-phenylpropanoate  (ISO)
tungsten  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Influence of lactoferrin feeding and injection against systemic staphylococcal infections in mice. Bhimani RS, etal., J Appl Microbiol. 1999 Jan;86(1):135-44.
2. A randomized, double-blind, placebo-controlled, phase II study of oral talactoferrin in combination with carboplatin and paclitaxel in previously untreated locally advanced or metastatic non-small cell lung cancer. Digumarti R, etal., J Thorac Oncol. 2011 Jun;6(6):1098-103. doi: 10.1097/JTO.0b013e3182156250.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. Lung injury after ozone exposure is iron dependent. Ghio AJ, etal., Am J Physiol Lung Cell Mol Physiol. 2007 Jan;292(1):L134-43. Epub 2006 Aug 11.
5. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
6. A phase 2 randomized, double-blind, placebo-controlled study of the safety and efficacy of talactoferrin in patients with severe sepsis. Guntupalli K, etal., Crit Care Med. 2013 Mar;41(3):706-16. doi: 10.1097/CCM.0b013e3182741551.
7. Involvement of protein kinase C in C5a-primed neutrophils for ANCA-mediated activation. Hao J, etal., Mol Immunol. 2013 May;54(1):68-73. doi: 10.1016/j.molimm.2012.10.041. Epub 2012 Nov 28.
8. Human lactoferrin-derived peptide's antifungal activities against disseminated Candida albicans infection. Lupetti A, etal., J Infect Dis. 2007 Nov 1;196(9):1416-24. Epub 2007 Oct 2.
9. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
10. Biliary lactoferrin concentrations are increased in active inflammatory bowel disease: a factor in the pathogenesis of primary sclerosing cholangitis? Pereira SP, etal., Clin Sci (Lond). 1998 Nov;95(5):637-44.
11. GOA pipeline RGD automated data pipeline
12. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
13. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
14. Comprehensive gene review and curation RGD comprehensive gene curation
15. Acute inflammatory proteins constitute the organic matrix of prostatic corpora amylacea and calculi in men with prostate cancer. Sfanos KS, etal., Proc Natl Acad Sci U S A. 2009 Mar 3;106(9):3443-8. doi: 10.1073/pnas.0810473106. Epub 2009 Feb 6.
16. ANCA with specificity for lactoferrin in systemic lupus erythematosus (SLE). Sinico RA, etal., Adv Exp Med Biol. 1993;336:385-7.
Additional References at PubMed
PMID:1599934   PMID:2981589   PMID:9596699   PMID:9727055   PMID:11083624   PMID:11907569   PMID:12037568   PMID:12390874   PMID:12522210   PMID:12788072   PMID:15155221   PMID:15166119  
PMID:15572693   PMID:16502470   PMID:16650524   PMID:17023661   PMID:17567961   PMID:18714013   PMID:19199708   PMID:20345905   PMID:21630459   PMID:22664934   PMID:23376485   PMID:23533145  
PMID:23580065   PMID:24383868   PMID:25193851   PMID:27313089   PMID:34716503  


Genomics

Comparative Map Data
Ltf
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88119,878,344 - 119,901,189 (+)NCBIGRCr8
mRatBN7.28110,999,948 - 111,022,795 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl8110,999,948 - 111,022,795 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx8116,614,671 - 116,637,494 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.08114,813,884 - 114,836,711 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.08112,656,706 - 112,679,539 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.08119,290,416 - 119,313,261 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8119,290,416 - 119,313,261 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08118,632,730 - 118,655,575 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48115,417,764 - 115,440,609 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.18115,437,256 - 115,458,062 (+)NCBI
Celera8110,282,264 - 110,305,105 (+)NCBICelera
Cytogenetic Map8q32NCBI
LTF
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38346,435,645 - 46,485,234 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl346,435,645 - 46,485,234 (-)EnsemblGRCh38hg38GRCh38
GRCh37346,477,136 - 46,526,724 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36346,452,500 - 46,481,399 (-)NCBINCBI36Build 36hg18NCBI36
Build 34346,452,500 - 46,481,399NCBI
Celera346,414,868 - 46,443,775 (-)NCBICelera
Cytogenetic Map3p21.31NCBI
HuRef346,519,882 - 46,548,964 (-)NCBIHuRef
CHM1_1346,427,517 - 46,456,606 (-)NCBICHM1_1
T2T-CHM13v2.0346,451,475 - 46,501,054 (-)NCBIT2T-CHM13v2.0
Ltf
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399110,848,360 - 110,871,834 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl9110,848,339 - 110,871,835 (+)EnsemblGRCm39 Ensembl
GRCm389111,019,292 - 111,042,766 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9111,019,271 - 111,042,767 (+)EnsemblGRCm38mm10GRCm38
MGSCv379110,921,796 - 110,945,270 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv369110,864,108 - 110,887,582 (+)NCBIMGSCv36mm8
Celera9110,742,738 - 110,766,162 (+)NCBICelera
Cytogenetic Map9F2NCBI
cM Map960.79NCBI
Ltf
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542025,580,359 - 25,604,331 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542025,580,449 - 25,604,277 (+)NCBIChiLan1.0ChiLan1.0
LTF
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2246,394,851 - 46,423,796 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1346,399,619 - 46,428,572 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0346,337,738 - 46,367,476 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1347,442,440 - 47,471,532 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl347,442,440 - 47,471,532 (-)Ensemblpanpan1.1panPan2
LTF
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12042,231,994 - 42,263,202 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2042,231,994 - 42,263,202 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2042,147,994 - 42,179,342 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02042,714,382 - 42,745,648 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2042,698,084 - 42,745,648 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12041,955,622 - 41,986,941 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02042,357,046 - 42,388,364 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02042,637,942 - 42,669,274 (+)NCBIUU_Cfam_GSD_1.0
Ltf
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118200,795,136 - 200,824,718 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936596344,274 - 373,952 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936596344,287 - 373,788 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LTF
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1329,413,886 - 29,445,739 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11329,413,886 - 29,445,751 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21332,577,743 - 32,609,425 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LTF
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1227,867,332 - 7,896,403 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl227,867,286 - 7,894,521 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041159,254,403 - 159,283,476 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ltf
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473074,636,522 - 74,656,886 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473074,636,554 - 74,656,817 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Ltf
119 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:292
Count of miRNA genes:177
Interacting mature miRNAs:201
Transcripts:ENSRNOT00000047752
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2303171Bp331Blood pressure QTL 3315.570.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)861290298119084929Rat
1549909Stresp11Stress response QTL 116.830.0019stress-related behavior trait (VT:0010451)number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)873473045118473045Rat
631210Bw3Body weight QTL35.9mesenteric fat pad mass (VT:0010427)mesenteric fat pad weight to body weight ratio (CMO:0000654)869349194112783834Rat
1358903Bp252Blood pressure QTL 25270.0001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)893965141123900184Rat
1554321Bmd3Bone mineral density QTL 37.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)840952565123900184Rat
9590292Uminl3Urine mineral level QTL 33.620.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)871888757116888757Rat
8694446Bw170Body weight QTL 17012.070.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)871888757116888757Rat
631650Stl6Serum triglyceride level QTL 640.0019blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)810378157112202585Rat
631653Bp125Blood pressure QTL 1253.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)866142385111142385Rat
724539Cm19Cardiac mass QTL 192.6heart mass (VT:0007028)calculated heart weight (CMO:0000073)8100149864120994388Rat
738011Anxrr9Anxiety related response QTL 96.1exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)893535351123900184Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)846531639119088626Rat
738014Anxrr15Anxiety related response QTL 153.60.005locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)895718998123900184Rat
2300182Bmd56Bone mineral density QTL 565.4femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)895718998123900184Rat
2300181Bmd55Bone mineral density QTL 555.70.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)876468691121468691Rat
1300171Bp184Blood pressure QTL 1843.66arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)870513503118219066Rat
1358893Bp263Blood pressure QTL 2635.01arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)893965141123900184Rat
2313400Anxrr25Anxiety related response QTL 25aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)889265192114019816Rat
8694200Abfw4Abdominal fat weight QTL 49.070.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)871888757116888757Rat
8694392Bw161Body weight QTL 1618.060.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)871888757116888757Rat
61437Cia6Collagen induced arthritis QTL 6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)882460758122812818Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 7 12 39 45 44 14 25 14 6 121 56 19 36 56 30

Sequence


Ensembl Acc Id: ENSRNOT00000047752   ⟹   ENSRNOP00000048806
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl8110,999,948 - 111,022,795 (+)Ensembl
Rnor_6.0 Ensembl8119,290,416 - 119,313,261 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000095263   ⟹   ENSRNOP00000090955
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl8110,999,948 - 111,020,561 (+)Ensembl
RefSeq Acc Id: NM_001106864   ⟹   NP_001100334
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88119,878,344 - 119,901,189 (+)NCBI
mRatBN7.28110,999,948 - 111,022,795 (+)NCBI
Rnor_6.08119,290,416 - 119,313,261 (+)NCBI
Rnor_5.08118,632,730 - 118,655,575 (+)NCBI
RGSC_v3.48115,417,764 - 115,440,609 (+)RGD
Celera8110,282,264 - 110,305,105 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001100334 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL77040 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000048806.2
  ENSRNOP00000090955.1
RefSeq Acc Id: NP_001100334   ⟸   NM_001106864
- Peptide Label: precursor
- UniProtKB: D3ZAB1 (UniProtKB/TrEMBL),   A6I3I7 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000048806   ⟸   ENSRNOT00000047752
Ensembl Acc Id: ENSRNOP00000090955   ⟸   ENSRNOT00000095263
Protein Domains
Transferrin-like

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZAB1-F1-model_v2 AlphaFold D3ZAB1 1-709 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13696344
Promoter ID:EPDNEW_R6868
Type:single initiation site
Name:Ltf_1
Description:lactotransferrin
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.08119,290,416 - 119,290,476EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1305445 AgrOrtholog
BioCyc Gene G2FUF-29037 BioCyc
Ensembl Genes ENSRNOG00000031779 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000047752.3 UniProtKB/TrEMBL
  ENSRNOT00000095263.1 UniProtKB/TrEMBL
Gene3D-CATH Periplasmic binding protein-like II UniProtKB/TrEMBL
InterPro Peptidase_S60 UniProtKB/TrEMBL
  Transferrin UniProtKB/TrEMBL
  Transferrin_Fe_BS UniProtKB/TrEMBL
KEGG Report rno:301034 UniProtKB/TrEMBL
NCBI Gene 301034 ENTREZGENE
PANTHER LACTOTRANSFERRIN UniProtKB/TrEMBL
  TRANSFERRIN UniProtKB/TrEMBL
Pfam Transferrin UniProtKB/TrEMBL
PhenoGen Ltf PhenoGen
PIRSF Transferrin UniProtKB/TrEMBL
PRINTS TRANSFERRIN UniProtKB/TrEMBL
PROSITE TRANSFERRIN_LIKE_1 UniProtKB/TrEMBL
  TRANSFERRIN_LIKE_2 UniProtKB/TrEMBL
  TRANSFERRIN_LIKE_3 UniProtKB/TrEMBL
  TRANSFERRIN_LIKE_4 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000031779 RatGTEx
SMART TR_FER UniProtKB/TrEMBL
Superfamily-SCOP Periplasmic binding protein-like II UniProtKB/TrEMBL
UniProt A0A8I6APJ2_RAT UniProtKB/TrEMBL
  A6I3I7 ENTREZGENE, UniProtKB/TrEMBL
  D3ZAB1 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Ltf  lactotransferrin   Ltf_predicted  lactotransferrin (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Ltf_predicted  lactotransferrin (predicted)      Symbol and Name status set to approved 70820 APPROVED