Gene: Lef1 (lymphoid enhancer binding factor 1) Rattus norvegicus
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Symbol: Lef1
Name: lymphoid enhancer binding factor 1
Description: ENCODES a protein that exhibits armadillo repeat domain binding (ortholog); beta-catenin binding (ortholog); C2H2 zinc finger domain binding (ortholog); INVOLVED IN animal organ regeneration; cell adhesion; kidney development; PARTICIPATES IN Wnt signaling, canonical pathway; acute myeloid leukemia pathway; arrhythmogenic right ventricular cardiomyopathy pathway; ASSOCIATED WITH Femoral Fractures; Animal Disease Models (ortholog); B-Cell Chronic Lymphocytic Leukemia (ortholog); FOUND IN nucleus; beta-catenin-TCF complex (ortholog); cytoplasm (ortholog); INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 1,2-dimethylhydrazine; 1,3-dinitrobenzene
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: LEF-1; lymphoid enhancer binding factor 1 short isoform; lymphoid enhancer-binding factor 1
Orthologs:
Homo sapiens (human) : LEF1 (lymphoid enhancer binding factor 1)  HGNC  Alliance
Mus musculus (house mouse) : Lef1 (lymphoid enhancer binding factor 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Lef1 (lymphoid enhancer binding factor 1)
Pan paniscus (bonobo/pygmy chimpanzee) : LEF1 (lymphoid enhancer binding factor 1)
Canis lupus familiaris (dog) : LEF1 (lymphoid enhancer binding factor 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Lef1 (lymphoid enhancer binding factor 1)
Sus scrofa (pig) : LEF1 (lymphoid enhancer binding factor 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.02236,232,115 - 236,345,061 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.02254,781,171 - 254,893,756 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42228,550,263 - 228,673,131 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12228,537,002 - 228,659,871 (+)NCBI
Celera2211,924,784 - 212,018,812 (+)NCBICelera
Cytogenetic Map2q43NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Lef1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 620241
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-01-30
Status: ACTIVE