Mir223 (microRNA 223) - Rat Genome Database

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Gene: Mir223 (microRNA 223) Rattus norvegicus
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Symbol: Mir223
Name: microRNA 223
RGD ID: 2325543
Description: Involved in several processes, including cellular response to mechanical stimulus; negative regulation of cardiac muscle cell apoptotic process; and negative regulation of cytokine production. Localizes to blood microparticle and extracellular exosome. Used to study acute myocardial infarction; brain ischemia; pulmonary hypertension; thrombophlebitis; and transient cerebral ischemia. Biomarker of artery disease (multiple); brain infarction (multiple); peptic esophagitis; and pulmonary fibrosis. Human ortholog(s) of this gene implicated in lung non-small cell carcinoma. Orthologous to human MIR223 (microRNA 223); INTERACTS WITH 2,5-hexanedione; aflatoxin B1; amphetamine.
Type: ncrna
RefSeq Status: PROVISIONAL
Also known as: microRNA mir-223; rno-mir-223
RGD Orthologs
Human
Mouse
Dog
Alliance Genes
More Info more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2X61,141,887 - 61,141,996 (+)NCBI
Rnor_6.0 EnsemblX65,367,812 - 65,367,921 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0X65,367,812 - 65,367,921 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0X66,205,958 - 66,206,067 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
CeleraX61,554,814 - 61,554,923 (+)NCBICelera
Cytogenetic MapXq22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
References

References - curated
1. Brianza-Padilla M, etal., PeerJ. 2018 Sep 13;6:e5567. doi: 10.7717/peerj.5567. eCollection 2018.
2. Calvente CJ, etal., J Clin Invest. 2019 Jul 11;130:4091-4109. doi: 10.1172/JCI122258.
3. Chen L, etal., Mol Immunol. 2018 Jan;93:38-46. doi: 10.1016/j.molimm.2017.11.008. Epub 2017 Nov 13.
4. Chen Y, etal., Exp Mol Med. 2017 Jun 23;49(6):e348. doi: 10.1038/emm.2017.80.
5. Chyrchel B, etal., Platelets. 2015;26(6):593-7. doi: 10.3109/09537104.2014.974527. Epub 2014 Oct 28.
6. Cuomo O, etal., Mol Ther Nucleic Acids. 2019 Dec 6;18:1063-1071. doi: 10.1016/j.omtn.2019.10.022. Epub 2019 Oct 28.
7. Dou L, etal., Oncol Res. 2019 Feb 5;27(2):261-268. doi: 10.3727/096504018X15219188894056. Epub 2018 Apr 3.
8. Giray BG, etal., Mol Biol Rep. 2014 Jul;41(7):4513-9. doi: 10.1007/s11033-014-3322-3. Epub 2014 Mar 5.
9. Hao S, etal., J Cell Physiol. 2019 May;234(5):6324-6335. doi: 10.1002/jcp.27363. Epub 2018 Sep 24.
10. He X, etal., Parasit Vectors. 2013 Sep 20;6:272. doi: 10.1186/1756-3305-6-272.
11. He Y, etal., Hepatology. 2019 Oct;70(4):1150-1167. doi: 10.1002/hep.30645. Epub 2019 Jun 5.
12. Hyrina A, etal., EBioMedicine. 2017 Sep;23:68-78. doi: 10.1016/j.ebiom.2017.08.020. Epub 2017 Aug 24.
13. Imura S, etal., Anticancer Res. 2017 Oct;37(10):5877-5883. doi: 10.21873/anticanres.12033.
14. Jacobsen DP, etal., Stress. 2020 Jan;23(1):77-86. doi: 10.1080/10253890.2019.1642320. Epub 2019 Jul 24.
15. Ji D, etal., Aging (Albany NY). 2020 Jan 29;12(2):1643-1655. doi: 10.18632/aging.102705. Epub 2020 Jan 29.
16. Jimenez Calvente C, etal., Mol Ther. 2020 Feb 5;28(2):653-663. doi: 10.1016/j.ymthe.2019.09.013. Epub 2019 Sep 13.
17. Kawashita Y, etal., J Hepatobiliary Pancreat Sci. 2017 Oct;24(10):576-583. doi: 10.1002/jhbp.500. Epub 2017 Oct 12.
18. Lee W, etal., Mol Cell Toxicol. 2016;12(3):243-253. doi: 10.1007/s13273-016-0029-7. Epub 2016 Oct 7.
19. Li HL, etal., Eur Rev Med Pharmacol Sci. 2020 Feb;24(4):2020-2027. doi: 10.26355/eurrev_202002_20380.
20. Li M, etal., Gut. 2017 Apr;66(4):705-715. doi: 10.1136/gutjnl-2016-311861. Epub 2016 Sep 27.
21. Li S, etal., Acta Neurobiol Exp (Wars). 2019;79(2):205-216.
22. Li Y, etal., J Biol Chem. 2019 Jul 5;294(27):10438-10448. doi: 10.1074/jbc.RA119.007755. Epub 2019 May 22.
23. Liu A, etal., Cell Prolif. 2019 Mar;52(2):e12550. doi: 10.1111/cpr.12550. Epub 2018 Dec 3.
24. Liu X, etal., Cell Physiol Biochem. 2018;46(4):1439-1454. doi: 10.1159/000489185. Epub 2018 Apr 19.
25. Liu X, etal., J Mol Cell Cardiol. 2018 May;118:133-146. doi: 10.1016/j.yjmcc.2018.03.018. Epub 2018 Mar 31.
26. Long Y, etal., Cardiovasc Toxicol. 2017 Jan;17(1):42-48. doi: 10.1007/s12012-015-9354-7.
27. Lu FB, etal., Mol Cells. 2019 Dec 31;42(12):906-918. doi: 10.14348/molcells.2019.2283.
28. Meloche J, etal., Am J Physiol Cell Physiol. 2015 Sep 15;309(6):C363-72. doi: 10.1152/ajpcell.00149.2015. Epub 2015 Jun 17.
29. Moen A, etal., J Transl Med. 2017 May 1;15(1):89. doi: 10.1186/s12967-017-1194-8.
30. Neudecker V, etal., Sci Transl Med. 2017 Sep 20;9(408). pii: 9/408/eaah5360. doi: 10.1126/scitranslmed.aah5360.
31. Oksuz Z, etal., Mol Biol Rep. 2015 Mar;42(3):713-20. doi: 10.1007/s11033-014-3819-9. Epub 2014 Nov 13.
32. Qadir XV, etal., Am J Pathol. 2015 Dec;185(12):3141-51. doi: 10.1016/j.ajpath.2015.08.020.
33. Qu SJ, etal., Eur Rev Med Pharmacol Sci. 2020 Apr;24(7):3951-3958. doi: 10.26355/eurrev_202004_20864.
34. RGD automated import pipeline for gene-chemical interactions
35. Schueller F, etal., Clin Sci (Lond). 2017 Jul 13;131(15):1971-1987. doi: 10.1042/CS20170218. Print 2017 Aug 1.
36. Sha R, etal., Med Sci Monit. 2019 Jun 25;25:4723-4733. doi: 10.12659/MSM.917213.
37. Shaker OG and Senousy MA, J Viral Hepat. 2017 Aug;24(8):636-644. doi: 10.1111/jvh.12696. Epub 2017 Mar 13.
38. Shan Z, etal., J Am Coll Cardiol. 2015 Jun 16;65(23):2526-37. doi: 10.1016/j.jacc.2015.03.570.
39. Song L, etal., Arch Biochem Biophys. 2012 Dec 15;528(2):204-11. doi: 10.1016/j.abb.2012.08.015. Epub 2012 Oct 6.
40. Streppel MM, etal., Clin Cancer Res. 2013 Aug 1;19(15):4067-78. doi: 10.1158/1078-0432.CCR-13-0601. Epub 2013 Jun 11.
41. Uemura R, etal., Int J Mol Sci. 2017 Jul 25;18(8). pii: ijms18081611. doi: 10.3390/ijms18081611.
42. Vickers KC, etal., Proc Natl Acad Sci U S A. 2014 Oct 7;111(40):14518-23. doi: 10.1073/pnas.1215767111. Epub 2014 Sep 22.
43. Wang B, etal., Biomed Pharmacother. 2019 Jun;114:108683. doi: 10.1016/j.biopha.2019.108683. Epub 2019 Apr 1.
44. Wang H, etal., IUBMB Life. 2018 Jun;70(6):479-490. doi: 10.1002/iub.1747. Epub 2018 Apr 29.
45. Wang X, etal., PLoS One. 2017 Sep 8;12(9):e0184292. doi: 10.1371/journal.pone.0184292. eCollection 2017.
46. Wu Y, etal., Zhonghua Er Ke Za Zhi. 2014 Jan;52(1):28-33.
47. Xie XJ, etal., Mol Pain. 2017 Jan-Dec;13:1744806917706582. doi: 10.1177/1744806917706582.
48. Xu J, etal., Mol Carcinog. 2011 Feb;50(2):136-42. doi: 10.1002/mc.20712. Epub 2010 Dec 10.
49. Yang F, etal., Cell Death Dis. 2018 Jan 9;9(1):12. doi: 10.1038/s41419-017-0020-9.
50. Yang F, etal., Cell Physiol Biochem. 2014;34(6):2137-52. doi: 10.1159/000369658. Epub 2014 Dec 2.
51. Yu CH, etal., Dig Dis Sci. 2009 Nov;54(11):2362-6. doi: 10.1007/s10620-008-0629-8. Epub 2008 Dec 23.
52. Yuen CM, etal., Am J Transl Res. 2017 Apr 15;9(4):1651-1666. eCollection 2017.
53. Zhao ZH, etal., Mol Cell Biochem. 2018 Jun;443(1-2):47-56. doi: 10.1007/s11010-017-3209-4. Epub 2017 Nov 7.
54. Zhou J, etal., Mol Med Rep. 2018 Oct;18(4):4051-4057. doi: 10.3892/mmr.2018.9385. Epub 2018 Aug 13.
Additional References at PubMed
PMID:16381832   PMID:16766679   PMID:18278031   PMID:18723672   PMID:18762567   PMID:18791161   PMID:19147652   PMID:20403161   PMID:20439489   PMID:21247879   PMID:24205035   PMID:25313822  
PMID:25792377   PMID:25875646   PMID:27226563   PMID:27322747   PMID:27979484   PMID:27999792   PMID:29663740   PMID:31210320   PMID:31212858   PMID:31799641   PMID:32337949   PMID:32926923  


Genomics

Comparative Map Data
Mir223
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2X61,141,887 - 61,141,996 (+)NCBI
Rnor_6.0 EnsemblX65,367,812 - 65,367,921 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0X65,367,812 - 65,367,921 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0X66,205,958 - 66,206,067 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
CeleraX61,554,814 - 61,554,923 (+)NCBICelera
Cytogenetic MapXq22NCBI
MIR223
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 EnsemblX66,018,870 - 66,018,979 (+)EnsemblGRCh38hg38GRCh38
GRCh38X66,018,870 - 66,018,979 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X65,238,712 - 65,238,821 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X65,155,436 - 65,155,545 (+)NCBINCBI36hg18NCBI36
CeleraX65,585,857 - 65,585,966 (+)NCBI
Cytogenetic MapXq12NCBI
HuRefX59,065,818 - 59,065,927 (+)NCBIHuRef
CHM1_1X65,131,742 - 65,131,851 (+)NCBICHM1_1
Mir223
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X95,286,423 - 95,286,532 (+)NCBIGRCm39mm39
GRCm39 EnsemblX95,286,423 - 95,286,532 (+)Ensembl
GRCm38X96,242,817 - 96,242,926 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX96,242,817 - 96,242,926 (+)EnsemblGRCm38mm10GRCm38
MGSCv37X93,438,156 - 93,438,265 (+)NCBIGRCm37mm9NCBIm37
CeleraX83,247,617 - 83,247,726 (+)NCBICelera
Cytogenetic MapXC3NCBI
MIR223
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X50,838,131 - 50,838,233 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX50,838,131 - 50,838,233 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX41,675,998 - 41,676,100 (+)NCBI
ROS_Cfam_1.0X51,802,379 - 51,802,481 (+)NCBI
UMICH_Zoey_3.1X49,766,866 - 49,766,968 (+)NCBI
UNSW_CanFamBas_1.0X51,114,791 - 51,114,893 (+)NCBI
UU_Cfam_GSD_1.0X51,030,133 - 51,030,235 (+)NCBI


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
61430Cia18Collagen induced arthritis QTL 183.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)X15688119127888215Rat
1598837Memor13Memory QTL 133.2exploratory behavior trait (VT:0010471)difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X44320616158345622Rat
738035Stresp1Stress response QTL 14.960.000011stress-related behavior trait (VT:0010451)defensive burying - copingX44557974120045269Rat
70221Bp56Blood pressure QTL 564.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)X6139809770352120Rat

miRNA Target Status

Confirmed Targets
Gene TargetMature miRNAMethod NameResult TypeData TypeSupport TypePMID
Vimrno-miR-223-3pMirtarbaseexternal_infoMicroarrayFunctional MTI (Weak)18258830

Predicted Targets
Summary Value
Count of predictions:12615
Count of gene targets:7052
Count of transcripts:7639
Interacting mature miRNAs:rno-miR-223-3p, rno-miR-223-5p
Prediction methods:Microtar, Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 8 2 6
Low 7 37 21 11 21 6 6 3 5 13 5 6
Below cutoff 10 8 8 8 1 1 1 3 3 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NR_031936 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JACYVU010000417 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000053628
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 EnsemblX65,367,812 - 65,367,921 (+)Ensembl
RefSeq Acc Id: NR_031936
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X61,141,887 - 61,141,996 (+)NCBI
Rnor_6.0X65,367,812 - 65,367,921 (+)NCBI
Rnor_5.0X66,205,958 - 66,206,067 (+)NCBI
CeleraX61,554,814 - 61,554,923 (+)NCBI
Sequence:
Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2325543 AgrOrtholog
Ensembl Genes ENSRNOG00000035505 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000053628 ENTREZGENE
miRBase MI0000963 ENTREZGENE
NCBI Gene 100314060 ENTREZGENE
PhenoGen Mir223 PhenoGen
RNAcentral URS00000D5CE2 RNACentral
  URS00000F11D1 RNACentral
  URS00006291D1 RNACentral


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-08-14 Mir223  microRNA 223  Mir223  microRNA mir-223  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2010-06-02 Mir223  microRNA mir-223      Symbol and Name status set to provisional 70820 PROVISIONAL