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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Vascular System Injuries
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Accession:DOID:9000352 term browser browse the term
Definition:Injuries to blood vessels caused by laceration, contusion, puncture, or crush and other types of injuries. Symptoms vary by site and mode of injuries and may include bleeding, bruising, swelling, pain, and numbness. It does not include injuries secondary to pathologic function or diseases such as ATHEROSCLEROSIS.
Synonyms:exact_synonym: Vascular Injuries;   Vascular Injury;   Vascular System Injury
 primary_id: MESH:D057772;   RDO:0007794



show annotations for term's descendants           Sort by:
Vascular System Injuries term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace angiotensin I converting enzyme susceptibility IAGP
ISO
DNA:repeat:intron:IVS13+40(CA)?-26 (rat)
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:19258495 PMID:9484988 RGD:8157602 NCBI chr10:91,410,129...91,430,246
Ensembl chr10:90,910,316...90,931,131
JBrowse link
G Agtr1a angiotensin II receptor, type 1a ISO CTD Direct Evidence: marker/mechanism CTD PMID:16982965 NCBI chr17:34,383,397...34,435,523
Ensembl chr17:34,174,429...34,226,946
JBrowse link
G Agtr2 angiotensin II receptor, type 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16982965 NCBI chr  X:116,914,320...116,918,504
Ensembl chr  X:112,120,228...112,124,057
JBrowse link
G Apoe apolipoprotein E IEP
ISO
protein:decreased expression:plasma (rat) RGD PMID:21416056 PMID:21163611 RGD:5509868, RGD:6904145 NCBI chr 1:88,481,889...88,485,816
Ensembl chr 1:79,353,916...79,357,932
JBrowse link
G Atp7a ATPase copper transporting alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:20671235 NCBI chr  X:75,159,635...75,267,094
Ensembl chr  X:71,094,202...71,198,354
JBrowse link
G Bdkrb1 bradykinin receptor B1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16982965 NCBI chr 6:130,275,631...130,284,968
Ensembl chr 6:124,510,870...124,513,747
JBrowse link
G Bdkrb2 bradykinin receptor B2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16982965 NCBI chr 6:130,237,055...130,267,205
Ensembl chr 6:124,472,566...124,502,497
JBrowse link
G Grk2 G protein-coupled receptor kinase 2 IEP protein:increased expression:aorta (rat) RGD PMID:28653218 RGD:13513975 NCBI chr 1:211,010,259...211,031,013
Ensembl chr 1:201,581,480...201,601,582
JBrowse link
G Hmox1 heme oxygenase 1 ISO CTD Direct Evidence: therapeutic CTD PMID:19234301 NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Id2 inhibitor of DNA binding 2 IEP protein:increased expression:carotid artery, blood vessel wall (rat) RGD PMID:11706002 RGD:619536 NCBI chr 6:47,469,162...47,470,995
Ensembl chr 6:41,728,946...41,744,400
JBrowse link
G Iqgap1 IQ motif containing GTPase activating protein 1 IEP RGD PMID:15217908 RGD:11049588 NCBI chr 1:144,088,788...144,178,989
Ensembl chr 1:134,679,586...134,769,755
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 ISO CTD Direct Evidence: therapeutic CTD PMID:19234301 NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Pecam1 platelet and endothelial cell adhesion molecule 1 IDA RGD PMID:22552115 RGD:6484736 NCBI chr10:92,090,263...92,152,002
Ensembl chr10:91,590,521...91,652,116
JBrowse link
G Pf4 platelet factor 4 ISO RGD PMID:23568488 RGD:329901761 NCBI chr14:17,582,477...17,583,392
Ensembl chr14:17,298,308...17,299,365
JBrowse link
G S1pr1 sphingosine-1-phosphate receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29609002 NCBI chr 2:206,309,715...206,314,070
Ensembl chr 2:203,621,587...203,629,681
JBrowse link
G Sell selectin L ameliorates IMP RGD PMID:1717513 RGD:597015750 NCBI chr13:78,950,100...78,969,604
Ensembl chr13:76,416,915...76,436,456
JBrowse link
G Spp1 secreted phosphoprotein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11868353 NCBI chr14:5,613,569...5,620,695
Ensembl chr14:5,308,885...5,315,162
JBrowse link
G Tnf tumor necrosis factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:19234301 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,622,011...3,624,629
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 19142
    Wounds and Injuries 998
      Vascular System Injuries 18
        vascular toxicity 0
Path 2
Term Annotations click to browse term
  disease 19142
    disease of anatomical entity 18455
      cardiovascular system disease 5547
        vascular disease 4029
          Vascular System Injuries 18
            vascular toxicity 0
paths to the root