Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Ifnl3 (interferon, lambda 3) Rattus norvegicus
Analyze
Symbol: Ifnl3
Name: interferon, lambda 3
RGD ID: 1589046
Description: Predicted to have signaling receptor binding activity. Predicted to be involved in defense response to virus; innate immune response; and mucosal immune response. Predicted to localize to extracellular space. Human ortholog(s) of this gene implicated in cryoglobulinemia; hepatitis C; liver cirrhosis; and thrombocytopenia. Orthologous to several human genes including IFNL3 (interferon lambda 3); PARTICIPATES IN Jak-Stat signaling pathway; INTERACTS WITH bisphenol A; benzo[a]pyrene (ortholog); folic acid (ortholog).
Type: protein-coding
RefSeq Status: MODEL
Also known as: Il28b; interferon lambda-2-like; interleukin 28B; LOC685840; LOC685861; similar to interferon-lambda2
Orthologs:
Homo sapiens (human) : IFNL3 (interferon lambda 3)  HGNC  Alliance
Mus musculus (house mouse) : Ifnl2 (interferon lambda 2)  MGI  Alliance
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0185,236,243 - 85,237,775 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl185,236,243 - 85,237,775 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0186,450,831 - 86,452,363 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4183,617,808 - 83,619,340 (-)NCBIRGSC3.4rn4RGSC3.4
Celera178,209,346 - 78,210,878 (+)NCBICelera
Cytogenetic Map1q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Ifnl3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1589046
Created: 2006-11-19
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.