Endog (endonuclease G) - Rat Genome Database

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Gene: Endog (endonuclease G) Rattus norvegicus
Symbol: Endog
Name: endonuclease G
RGD ID: 1310763
Description: Enables DNA nuclease activity. Involved in several processes, including cellular response to glucose stimulus; positive regulation of apoptotic DNA fragmentation; and positive regulation of hydrogen peroxide-mediated programmed cell death. Located in perikaryon and perinuclear region of cytoplasm. Biomarker of brain ischemia; congestive heart failure; muscular atrophy; and visual epilepsy. Orthologous to human ENDOG (endonuclease G); PARTICIPATES IN apoptotic cell death pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol; acetamide.
Type: protein-coding
Previously known as: endonuclease G, mitochondrial; LOC362100
RGD Orthologs
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Rat AssemblyChrPosition (strand)SourceGenome Browsers
mRatBN7.2313,449,113 - 13,451,715 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl313,449,086 - 13,451,932 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx316,521,074 - 16,523,700 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.031,414,746 - 1,417,374 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0323,359,321 - 23,361,921 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.038,741,833 - 8,744,414 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl38,741,766 - 8,744,592 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0314,094,275 - 14,096,910 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.439,184,023 - 9,187,524 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera38,222,701 - 8,225,752 (+)NCBICelera
Cytogenetic Map3p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-Tetrandrine  (ISO)
(1->4)-beta-D-glucan  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-methylcholine  (ISO)
3-chloropropane-1,2-diol  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroperoxycyclophosphamide  (ISO)
4-nitrophenol  (ISO)
5-fluorouracil  (ISO)
acetamide  (EXP)
acrylamide  (ISO)
aldehydo-D-glucose  (EXP,ISO)
amitrole  (EXP)
anthra[1,9-cd]pyrazol-6(2H)-one  (EXP)
arsane  (ISO)
arsenic atom  (ISO)
atrazine  (ISO)
Auriculasin  (ISO)
bisphenol A  (EXP,ISO)
bufalin  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (EXP)
canertinib  (ISO)
cantharidin  (ISO)
carbamazepine  (ISO)
casticin  (ISO)
chromium(6+)  (EXP,ISO)
chrysazin  (ISO)
cisplatin  (ISO)
clofibrate  (ISO)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) chloride  (ISO)
copper(II) sulfate  (ISO)
cycloheximide  (ISO)
cyclosporin A  (ISO)
D-glucose  (EXP,ISO)
deguelin  (ISO)
dexamethasone  (ISO)
dibutyl phthalate  (EXP)
diclofenac  (ISO)
dicrotophos  (ISO)
dimethyl sulfoxide  (ISO)
dioxygen  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
elemental selenium  (ISO)
ellagic acid  (ISO)
ethanol  (ISO)
fisetin  (ISO)
folic acid  (ISO)
gentamycin  (EXP)
glucose  (EXP,ISO)
hydrogen peroxide  (EXP,ISO)
isoflavones  (ISO)
Lupiwighteone  (ISO)
methotrexate  (ISO)
N-acetyl-L-cysteine  (ISO)
ochratoxin A  (EXP)
ouabain  (ISO)
ozone  (ISO)
paracetamol  (EXP,ISO)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phorbol 13-acetate 12-myristate  (ISO)
pirinixic acid  (ISO)
potassium dichromate  (ISO)
quercetin  (ISO)
resveratrol  (ISO)
rotenone  (ISO)
SB 431542  (ISO)
selenium atom  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenite  (ISO)
sulforaphane  (ISO)
sulindac  (ISO)
tebufenpyrad  (ISO)
tetrachloroethene  (ISO)
tetracycline  (ISO)
thapsigargin  (ISO)
thioacetamide  (EXP)
thiomalic acid  (EXP)
titanium dioxide  (ISO)
tributylstannane  (ISO)
trichostatin A  (ISO)
Triptolide  (ISO)
triptonide  (ISO)
trovafloxacin  (ISO)
tungsten  (ISO)
tunicamycin  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
vitamin E  (ISO)

Molecular Pathway Annotations     Click to see Annotation Detail View

References - curated
# Reference Title Reference Citation
1. A Ca2+-induced mitochondrial permeability transition causes complete release of rat liver endonuclease G activity from its exclusive location within the mitochondrial intermembrane space. Identification of a novel endo-exonuclease activity residing within the mitochondrial matrix. Davies AM, etal., Nucleic Acids Res. 2003 Feb 15;31(4):1364-73.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. Involvement of endonuclease G in nucleosomal DNA fragmentation under sustained endogenous oxidative stress. Ishihara Y and Shimamoto N, J Biol Chem. 2006 Mar 10;281(10):6726-33. Epub 2006 Jan 4.
5. Naringenin prevents high glucose-induced mitochondria-mediated apoptosis involving AIF, Endo-G and caspases. Kapoor R, etal., Apoptosis. 2013 Jan;18(1):9-27. doi: 10.1007/s10495-012-0781-7.
6. Age-related differences in apoptosis with disuse atrophy in soleus muscle. Leeuwenburgh C, etal., Am J Physiol Regul Integr Comp Physiol. 2005 May;288(5):R1288-96. Epub 2005 Jan 13.
7. Mitochondrial fission controls DNA fragmentation by regulating endonuclease G. Li J, etal., Free Radic Biol Med. 2010 Aug 15;49(4):622-31. doi: 10.1016/j.freeradbiomed.2010.05.021. Epub 2010 Jun 1.
8. Intranuclear localization of apoptosis-inducing factor and endonuclease G involves in peroxynitrite-induced apoptosis of spiral ganglion neurons. Liu W, etal., Neurol Res. 2012 Dec;34(10):915-22. doi: 10.1179/1743132812Y.0000000098. Epub 2012 Sep 20.
9. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
10. Endonuclease G expression in thalamic reticular nucleus after global cerebral ischemia. Nielsen M, etal., Exp Brain Res. 2008 Sep;190(1):81-9. doi: 10.1007/s00221-008-1452-3. Epub 2008 Jun 21.
11. Ovariectomy and 17beta-estradiol replacement play a role on the expression of Endonuclease-G and phosphorylated cyclic AMP response element-binding (CREB) protein in hippocampus. Pereira RT, etal., Mol Cell Endocrinol. 2014 Jan 25;382(1):227-33. doi: 10.1016/j.mce.2013.09.037. Epub 2013 Oct 9.
12. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
13. GOA pipeline RGD automated data pipeline
14. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
15. Natural terpenes prevent mitochondrial dysfunction, oxidative stress and release of apoptotic proteins during nimesulide-hepatotoxicity in rats. Singh BK, etal., PLoS One. 2012;7(4):e34200. doi: 10.1371/journal.pone.0034200. Epub 2012 Apr 3.
16. Response of caspase-independent apoptotic factors to high salt diet-induced heart failure. Siu PM, etal., J Mol Cell Cardiol. 2007 Mar;42(3):678-86. Epub 2007 Jan 9.
17. Protective effect of caspase inhibition on compression-induced muscle damage. Teng BT, etal., J Physiol. 2011 Jul 1;589(Pt 13):3349-69. doi: 10.1113/jphysiol.2011.209619. Epub 2011 May 3.
18. Overexpression of SOD1 in transgenic rats attenuates nuclear translocation of endonuclease G and apoptosis after spinal cord injury. Yu F, etal., J Neurotrauma. 2006 May;23(5):595-603.
19. BNIP3 upregulation and EndoG translocation in delayed neuronal death in stroke and in hypoxia. Zhang Z, etal., Stroke. 2007 May;38(5):1606-13. Epub 2007 Mar 22.
20. Nuclear translocation of mitochondrial cytochrome c, lysosomal cathepsins B and D, and three other death-promoting proteins within the first 60 minutes of generalized seizures. Zhao S, etal., J Neurosci Res. 2010 Jun;88(8):1727-37. doi: 10.1002/jnr.22338.
Additional References at PubMed
PMID:14651853   PMID:14663139   PMID:16754658   PMID:16767516   PMID:16873557   PMID:17050806   PMID:18312415   PMID:18614015   PMID:19737385   PMID:21437288   PMID:21979051  


Comparative Map Data
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
mRatBN7.2313,449,113 - 13,451,715 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl313,449,086 - 13,451,932 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx316,521,074 - 16,523,700 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.031,414,746 - 1,417,374 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0323,359,321 - 23,361,921 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.038,741,833 - 8,744,414 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl38,741,766 - 8,744,592 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0314,094,275 - 14,096,910 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.439,184,023 - 9,187,524 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera38,222,701 - 8,225,752 (+)NCBICelera
Cytogenetic Map3p12NCBI
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh389128,818,500 - 128,822,676 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl9128,818,500 - 128,822,676 (+)EnsemblGRCh38hg38GRCh38
GRCh379131,580,779 - 131,584,955 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 369130,620,600 - 130,624,776 (+)NCBINCBI36Build 36hg18NCBI36
Build 349128,660,332 - 128,664,509NCBI
Celera9102,231,564 - 102,235,740 (+)NCBICelera
Cytogenetic Map9q34.11NCBI
HuRef9101,189,778 - 101,193,954 (+)NCBIHuRef
CHM1_19131,731,780 - 131,735,956 (+)NCBICHM1_1
T2T-CHM13v2.09141,023,301 - 141,027,477 (+)NCBIT2T-CHM13v2.0
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm39230,061,525 - 30,064,057 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl230,061,505 - 30,064,081 (+)EnsemblGRCm39 Ensembl
GRCm38230,171,408 - 30,174,069 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl230,171,493 - 30,174,069 (+)EnsemblGRCm38mm10GRCm38
MGSCv37230,027,044 - 30,029,589 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36229,993,533 - 29,996,078 (+)NCBIMGSCv36mm8
Celera229,875,396 - 29,877,941 (+)NCBICelera
Cytogenetic Map2BNCBI
cM Map221.29NCBI
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
ChiLan1.0 EnsemblNW_0049555701,200,996 - 1,203,566 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555701,200,461 - 1,203,566 (+)NCBIChiLan1.0ChiLan1.0
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
NHGRI_mPanPan1910,530,841 - 10,534,838 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0999,941,856 - 99,945,957 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.19128,609,839 - 128,613,353 (+)NCBIpanpan1.1PanPan1.1panPan2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
CanFam3.1954,809,470 - 54,812,795 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl954,809,530 - 54,813,042 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha954,004,973 - 54,008,297 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0955,730,508 - 55,733,832 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl955,730,568 - 55,734,098 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1954,491,141 - 54,494,468 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0954,803,909 - 54,807,233 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0954,897,321 - 54,900,646 (-)NCBIUU_Cfam_GSD_1.0
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
HiC_Itri_2NW_024404947196,513,430 - 196,519,544 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648716,282,398 - 16,285,418 (+)EnsemblSpeTri2.0
SpeTri2.0NW_00493648716,282,115 - 16,285,486 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
Sscrofa11.1 Ensembl1269,154,090 - 269,157,788 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11269,153,955 - 269,157,789 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21303,170,007 - 303,173,838 (+)NCBISscrofa10.2Sscrofa10.2susScr3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
ChlSab1.1129,322,828 - 9,326,833 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl129,322,892 - 9,326,549 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666096150,312 - 154,313 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
HetGla_female_1.0 EnsemblNW_0046247606,193,173 - 6,196,374 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247606,193,168 - 6,196,209 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Variants in Endog
19 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:85
Count of miRNA genes:77
Interacting mature miRNAs:79
Prediction methods:Microtar, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
70202Alc19Alcohol consumption QTL 192.5drinking behavior trait (VT:0001422)ethanol intake volume to total fluid intake volume ratio (CMO:0001591)3127494778Rat
631679Cm10Cardiac mass QTL 107.340.0001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)3131158234Rat
631831Alc8Alcohol consumption QTL 82.7consumption behavior trait (VT:0002069)calculated ethanol drink intake rate (CMO:0001615)3133230976Rat
61468Bp15Blood pressure QTL 154.4blood pressure trait (VT:0000183)diastolic blood pressure (CMO:0000005)3133278763Rat
61468Bp15Blood pressure QTL 154.4blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)3133278763Rat
61468Bp15Blood pressure QTL 154.4blood pressure trait (VT:0000183)pulse pressure (CMO:0000292)3133278763Rat
631545Bp85Blood pressure QTL 853.1arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3133278763Rat
4889966Bss95Bone structure and strength QTL 954.4tibia area (VT:1000281)tibia-fibula cross-sectional area (CMO:0001718)3136847613Rat
2312664Scl62Serum cholesterol level QTL 620.05blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)3138710544Rat
631568Bp92Blood pressure QTL 922.20.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3139874793Rat
2290452Scl56Serum cholesterol level QTL 562.26blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)3191609953Rat
1298526Arunc3Aerobic running capacity QTL 32.2exercise endurance trait (VT:0002332)maximum distance run on treadmill (CMO:0001406)3822719433703538Rat
10401810Kidm53Kidney mass QTL 53kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)3822719447233430Rat
70203Gcr2Gastric cancer resistance QTL 22.6stomach morphology trait (VT:0000470)stomach tumor susceptibility score (CMO:0002043)3865816227494778Rat
1358357Srcrtb1Stress Responsive Cort Basal QTL 16.360.002blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)3865816227494778Rat
6893355Bw101Body weight QTL 1010.40.38body mass (VT:0001259)body weight (CMO:0000012)31077870430357018Rat
6893363Bw105Body weight QTL 1052.60.0036body mass (VT:0001259)body weight (CMO:0000012)31077870430357018Rat
1558654Bw56Body weight QTL 564.50.0000171body mass (VT:0001259)body weight (CMO:0000012)31077870430357018Rat
70191BpQTLcluster4Blood pressure QTL cluster 43arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)31077870450302886Rat
70191BpQTLcluster4Blood pressure QTL cluster 43arterial blood pressure trait (VT:2000000)absolute change in systolic blood pressure (CMO:0000607)31077870450302886Rat
1558647Cm46Cardiac mass QTL 465.40.0000055heart mass (VT:0007028)heart wet weight (CMO:0000069)31077882330356773Rat
1558650Cm48Cardiac mass QTL 4840.0001heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)31077882330356773Rat
1558657Cm43Cardiac mass QTL 436.60.0000000293heart mass (VT:0007028)heart wet weight (CMO:0000069)31077882330356773Rat
1358905Hrtrt17Heart rate QTL 175.90.000014heart pumping trait (VT:2000009)heart rate (CMO:0000002)31086191289878372Rat

Markers in Region
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2313,451,323 - 13,451,508 (+)MAPPERmRatBN7.2
Rnor_6.038,744,023 - 8,744,207NCBIRnor6.0
Rnor_5.0314,096,519 - 14,096,703UniSTSRnor5.0
RGSC_v3.439,187,133 - 9,187,317UniSTSRGSC3.4
Celera38,225,361 - 8,225,545UniSTS
RH 3.4 Map352.5UniSTS
Cytogenetic Map3p12UniSTS
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2313,451,794 - 13,451,908 (+)MAPPERmRatBN7.2
Rnor_6.038,744,494 - 8,744,607NCBIRnor6.0
Rnor_5.0314,096,990 - 14,097,103UniSTSRnor5.0
RGSC_v3.439,187,604 - 9,187,717UniSTSRGSC3.4
Celera38,225,832 - 8,225,945UniSTS
RH 3.4 Map351.81UniSTS
Cytogenetic Map3p12UniSTS
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2313,451,266 - 13,451,420 (+)MAPPERmRatBN7.2
Rnor_6.038,743,966 - 8,744,119NCBIRnor6.0
Rnor_5.0314,096,462 - 14,096,615UniSTSRnor5.0
RGSC_v3.439,187,076 - 9,187,229UniSTSRGSC3.4
Celera38,225,304 - 8,225,457UniSTS
Cytogenetic Map3p12UniSTS


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
Medium 43 2 2 2 8 11 18 20 3 8
Low 3 55 39 19 39 56 15 38 11
Below cutoff


RefSeq Acc Id: ENSRNOT00000021531   ⟹   ENSRNOP00000021531
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl313,449,086 - 13,451,932 (+)Ensembl
Rnor_6.0 Ensembl38,741,766 - 8,744,592 (+)Ensembl
RefSeq Acc Id: NM_001034938   ⟹   NP_001030110
Rat AssemblyChrPosition (strand)Source
mRatBN7.2313,449,113 - 13,451,715 (+)NCBI
Rnor_6.038,741,833 - 8,744,414 (+)NCBI
Rnor_5.0314,094,275 - 14,096,910 (+)NCBI
RGSC_v3.439,184,023 - 9,187,524 (+)RGD
Celera38,222,701 - 8,225,752 (+)RGD
Protein Sequences
Protein RefSeqs NP_001030110 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein BAE44115 (Get FASTA)   NCBI Sequence Viewer  
  EDL93340 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001030110   ⟸   NM_001034938
- Peptide Label: precursor
- UniProtKB: Q3V5X8 (UniProtKB/TrEMBL),   A6JTV7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000021531   ⟸   ENSRNOT00000021531

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q3V5X8-F1-model_v2 AlphaFold Q3V5X8 1-294 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1310763 AgrOrtholog
BioCyc Gene G2FUF-50231 BioCyc
Ensembl Genes ENSRNOG00000016033 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000021531 ENTREZGENE
  ENSRNOP00000021531.3 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000021531 ENTREZGENE
  ENSRNOT00000021531.7 UniProtKB/TrEMBL
Gene3D-CATH 3.40.570.10 UniProtKB/TrEMBL
InterPro DNA/RNA_endonuclease_AS UniProtKB/TrEMBL
  DNA/RNA_non-sp_Endonuclease UniProtKB/TrEMBL
  DNA/RNA_non-sp_Endonuclease_sf UniProtKB/TrEMBL
  Extracellular_endonuc_su_A UniProtKB/TrEMBL
  His-Me_finger_sf UniProtKB/TrEMBL
  Non-specific_endonuclease UniProtKB/TrEMBL
KEGG Report rno:362100 UniProtKB/TrEMBL
  PTHR13966 UniProtKB/TrEMBL
Pfam Endonuclease_NS UniProtKB/TrEMBL
PhenoGen Endog PhenoGen
SMART Endonuclease_NS UniProtKB/TrEMBL
Superfamily-SCOP SSF54060 UniProtKB/TrEMBL
UniProt Secondary Q3V5X8 UniProtKB/TrEMBL

Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2005-12-06 Endog  endonuclease G  Endog_predicted  endonuclease G (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Endog_predicted  endonuclease G (predicted)      Symbol and Name status set to approved 70820 APPROVED